Ralph DeBerardinis
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American scientist
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Ralph DeBerardinisbiology Degrees
Biology
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Biochemistry
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Biology
Ralph DeBerardinis's Degrees
- Doctorate Medicine University of Pennsylvania
- PhD Biochemistry University of Pennsylvania
Why Is Ralph DeBerardinis Influential?
(Suggest an Edit or Addition)According to Wikipedia, Ralph J. DeBerardinis is an American physician-scientist, the chief of the Division of Pediatric Genetics and Metabolism at the Children’s Medical Center Research Institute at UT Southwestern and a professor at the University of Texas Southwestern Medical Center. DeBerardinis became a Howard Hughes Medical Institute Investigator in 2018. DeBerardinis was elected to the National Academy of Medicine in 2020. DeBerardinis is known for his contributions to research on cancer and pediatric inborn errors of metabolism.
Ralph DeBerardinis's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. (2008) (3478)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
- Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis (2007) (2213)
- Fundamentals of cancer metabolism (2016) (1718)
- Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction (2008) (1709)
- Understanding the Intersections between Metabolism and Cancer Biology (2017) (1324)
- Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer (2010) (1106)
- Reductive carboxylation supports growth in tumor cells with defective mitochondria (2011) (1105)
- Metabolic pathways promoting cancer cell survival and growth (2015) (1014)
- Role of PFKFB3-Driven Glycolysis in Vessel Sprouting (2013) (1013)
- Brick by brick: metabolism and tumor cell growth. (2008) (975)
- High Frequency Retrotransposition in Cultured Mammalian Cells (1996) (944)
- Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation. (2010) (928)
- The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. (2010) (916)
- Glutamine and cancer: cell biology, physiology, and clinical opportunities. (2013) (911)
- Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth. (2007) (878)
- Oxidative stress inhibits distant metastasis by human melanoma cells (2015) (868)
- Autophagy in metazoans: cell survival in the land of plenty (2005) (811)
- AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo. (2013) (763)
- Lactate Metabolism in Human Lung Tumors (2017) (763)
- Metabolic Heterogeneity in Human Lung Tumors (2016) (753)
- Metabolic reprogramming and cancer progression (2020) (662)
- Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research. (2011) (642)
- Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us? (2012) (638)
- Exon shuffling by L1 retrotransposition. (1999) (618)
- Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases (2014) (535)
- NRF2 regulates serine biosynthesis in non-small cell lung cancer (2015) (512)
- A Broad Nanoparticle-Based Strategy for Tumor Imaging by Nonlinear Amplification of Microenvironment Signals (2013) (496)
- Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport. (2014) (488)
- Hypoxia induces heart regeneration in adult mice (2016) (483)
- 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated glioma patients (2011) (479)
- A roadmap for interpreting (13)C metabolite labeling patterns from cells. (2015) (468)
- Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo. (2012) (460)
- Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase (2011) (437)
- Many human L1 elements are capable of retrotransposition (1997) (436)
- Pyruvate carboxylase is required for glutamine-independent growth of tumor cells (2011) (428)
- Reductive carboxylation supports redox homeostasis during anchorage-independent growth (2016) (426)
- Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling. (2009) (388)
- The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid β-oxidation (2005) (363)
- The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. (2007) (359)
- TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions. (2016) (348)
- Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. (2012) (336)
- Ascorbate regulates haematopoietic stem cell function and leukaemogenesis (2017) (329)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
- We need to talk about the Warburg effect (2020) (321)
- A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth. (2014) (287)
- Metabolism of [U‐13C]glucose in human brain tumors in vivo (2012) (283)
- Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects. (2014) (268)
- Determination of L1 retrotransposition kinetics in cultured cells. (2000) (260)
- Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity (2019) (247)
- Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development (2013) (245)
- The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling. (2013) (241)
- Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth. (2015) (237)
- Mechanisms and Implications of Metabolic Heterogeneity in Cancer. (2019) (236)
- The gut commensal Bacteroides thetaiotaomicron exacerbates enteric infection through modification of the metabolic landscape. (2014) (225)
- Metabolic heterogeneity confers differences in melanoma metastatic potential (2019) (222)
- Human Enteric Defensins (1996) (222)
- Mechanical regulation of glycolysis via cytoskeleton architecture (2020) (219)
- Phosphatidylinositol 3-Kinase-dependent Modulation of Carnitine Palmitoyltransferase 1A Expression Regulates Lipid Metabolism during Hematopoietic Cell Growth* (2006) (219)
- Is cancer a disease of abnormal cellular metabolism? New angles on an old idea (2008) (207)
- Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism (2017) (199)
- Designing a broad-spectrum integrative approach for cancer prevention and treatment. (2015) (194)
- A mouse model of human L1 retrotransposition (2002) (192)
- CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (2017) (191)
- 6-phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumor growth by inhibiting LKB1-AMPK signaling (2014) (189)
- A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals (2013) (186)
- Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8+ T Cells. (2019) (186)
- Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis. (2016) (177)
- An actively retrotransposing, novel subfamily of mouse L1 elements (1998) (174)
- Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells. (2012) (172)
- Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis (2015) (170)
- Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition (2014) (164)
- Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo. (2018) (164)
- PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth. (2015) (161)
- Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases. (2019) (161)
- Lipoic acid metabolism and mitochondrial redox regulation (2017) (160)
- Glutamine: pleiotropic roles in tumor growth and stress resistance (2011) (159)
- Systematic Identification of Molecular Subtype-Selective Vulnerabilities in Non-Small-Cell Lung Cancer (2013) (156)
- The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy. (2012) (155)
- MCT4 defines a glycolytic subtype of pancreatic cancer with poor prognosis and unique metabolic dependencies. (2014) (153)
- Dysregulated metabolism contributes to oncogenesis. (2015) (152)
- Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis (2018) (145)
- LKB1 and KEAP1/NRF2 pathways cooperatively promote metabolic reprogramming with enhanced glutamine dependence in KRAS-mutant lung adenocarcinoma. (2019) (142)
- Rapid amplification of a retrotransposon subfamily is evolving the mouse genome (1998) (139)
- Tumor Microenvironment, Metabolism, and Immunotherapy. (2020) (131)
- Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications (2018) (123)
- Applications of metabolomics to study cancer metabolism. (2018) (119)
- Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in acute lymphoblastic leukemia (2015) (116)
- Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers. (2018) (114)
- Role of Glutamine in Cancer: Therapeutic and Imaging Implications (2011) (113)
- MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses (2014) (110)
- Comparison of kinetic models for analysis of pyruvate‐to‐lactate exchange by hyperpolarized 13C NMR (2012) (108)
- Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels. (2014) (106)
- Cytochrome c Oxidase Activity Is a Metabolic Checkpoint that Regulates Cell Fate Decisions During T Cell Activation and Differentiation. (2017) (106)
- Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity. (2019) (104)
- Metabolic diversity in human non-small cell lung cancer (2014) (101)
- Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone (2015) (101)
- Regulation of Mitochondrial Biogenesis in Erythropoiesis by mTORC1-Mediated Protein Translation (2017) (96)
- Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth. (2014) (95)
- MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer (2019) (90)
- Serine metabolism: some tumors take the road less traveled. (2011) (89)
- Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia (2015) (89)
- IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma (2019) (85)
- Differential Glucose Requirement in Skin Homeostasis and Injury Identifies a Therapeutic Target for Psoriasis (2018) (85)
- Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation. (2019) (84)
- Spectrum of mutations in the renin–angiotensin system genes in autosomal recessive renal tubular dysgenesis (2012) (82)
- MYC-Driven Small-Cell Lung Cancer is Metabolically Distinct and Vulnerable to Arginine Depletion (2019) (82)
- Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid (2017) (81)
- Metabolic dysregulation in monogenic disorders and cancer — finding method in madness (2015) (80)
- Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart (2016) (79)
- Genetically-defined metabolic reprogramming in cancer (2012) (78)
- Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells (2013) (74)
- A comparative study of short‐ and long‐TE 1H MRS at 3 T for in vivo detection of 2‐hydroxyglutarate in brain tumors (2013) (74)
- Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer (2018) (73)
- Cutting Edge: Critical Role of Glycolysis in Human Plasmacytoid Dendritic Cell Antiviral Responses (2016) (73)
- Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors (2012) (71)
- NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone (2015) (69)
- Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells (2014) (67)
- A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels. (2014) (66)
- Meta‐analysis of clinical metabolic profiling studies in cancer: challenges and opportunities (2016) (65)
- Quantitative metabolic flux analysis reveals an unconventional pathway of fatty acid synthesis in cancer cells deficient for the mitochondrial citrate transport protein. (2017) (65)
- Analysis of hypoxia-induced metabolic reprogramming. (2014) (63)
- Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth. (2016) (61)
- LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment. (2015) (61)
- D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2 (2015) (60)
- A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles (2015) (60)
- Hypoxic metabolism in human hematopoietic stem cells (2015) (60)
- RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells (2018) (60)
- Analysis of the promoter from an expanding mouse retrotransposon subfamily. (1999) (59)
- Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism (2017) (57)
- The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1-mutant lung cancer (2020) (54)
- Simultaneous Steady-state and Dynamic 13C NMR Can Differentiate Alternative Routes of Pyruvate Metabolism in Living Cancer Cells* (2014) (52)
- Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma (2020) (52)
- The Hypoxic Epicardial and Subepicardial Microenvironment (2012) (51)
- The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism (2017) (51)
- Measurement of glycine in the human brain in vivo by 1H‐MRS at 3 T: application in brain tumors (2011) (50)
- Real-time Detection of Hepatic Gluconeogenic and Glycogenolytic States Using Hyperpolarized [2-13C]Dihydroxyacetone* (2014) (50)
- Metabolic changes in cancer cells upon suppression of MYC (2013) (49)
- Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone (2015) (48)
- p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas. (2019) (47)
- Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells (2015) (46)
- Penicillamine therapy for pediatric cystinuria: experience from a cohort of American children. (2008) (45)
- NRF 2 regulates serine biosynthesis in non-small cell lung cancer (2016) (44)
- Mutations in mitochondrial enzyme GPT2 cause metabolic dysfunction and neurological disease with developmental and progressive features (2016) (44)
- Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma (2016) (43)
- A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma (2019) (43)
- Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow. (2012) (42)
- Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma. (2017) (41)
- Exploring a glycolytic inhibitor for the treatment of an FH-deficient type-2 papillary RCC (2011) (41)
- Lkb1 deficiency confers glutamine dependency in polycystic kidney disease (2018) (41)
- EVIDENCE OF GLYCOLYSIS UPREGULATION AND PYRUVATE MITOCHONDRIAL OXIDATION MISMATCH DURING MECHANICAL UNLOADING OF THE FAILING HUMAN HEART: IMPLICATIONS FOR CARDIAC RELOADING AND CONDITIONING (2016) (40)
- Mitochondrial NADP+ is essential for proline biosynthesis during cell growth (2021) (39)
- Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer (2019) (38)
- Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans (2019) (38)
- A novel radiotracer to image glycogen metabolism in tumors by positron emission tomography. (2014) (38)
- Myoclonus in a patient with a deletion of the ε‐sarcoglycan locus on chromosome 7q21 (2003) (36)
- The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts (2017) (36)
- Loss of a Negative Regulator of mTORC1 Induces Aerobic Glycolysis and Altered Fiber Composition in Skeletal Muscle (2018) (35)
- Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria (2020) (34)
- γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A. (2019) (34)
- Analyzing Tumor Metabolism In Vivo (2017) (33)
- Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation (2019) (33)
- AACR Cancer Progress Report 2016 (2016) (32)
- Glutathione Depletion, Pentose Phosphate Pathway Activation, and Hemolysis in Erythrocytes Protecting Cancer Cells from Vitamin C-induced Oxidative Stress* (2016) (32)
- Isocitrate dehydrogenase 1/2 mutational analyses and 2‐hydroxyglutarate measurements in Wilms tumors (2011) (32)
- Glucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine (2016) (32)
- Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI. (2017) (31)
- 1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer (2020) (31)
- Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction (2014) (31)
- Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non–Small Cell Lung Cancer and Its Potential as a Circulating Biomarker (2015) (29)
- Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism (2018) (28)
- Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs. (2015) (28)
- Selectively Impairs p 53-Deficient Tumor Cell Growth Systemic Treatment with the Antidiabetic Drug Metformin (2007) (27)
- Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small cell lung cancer. (2020) (26)
- Cancer metabolism: When more is less (2012) (25)
- Myoclonus in a patient with a deletion of the epsilon-sarcoglycan locus on chromosome 7q21. (2003) (25)
- Glycine by MR spectroscopy is an imaging biomarker of glioma aggressiveness. (2020) (25)
- Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer (2021) (25)
- Oxidation of [U‐13C]glucose in the human brain at 7T under steady state conditions (2017) (25)
- Wilms Tumor in a Child with L-2-hydroxyglutaric Aciduria (2010) (24)
- 2-hydroxyglutarate detection by magnetic resonance spectroscopy in subjects with IDH-mutated gliomas (2015) (24)
- Gain‐of‐function variants in the ODC1 gene cause a syndromic neurodevelopmental disorder associated with macrocephaly, alopecia, dysmorphic features, and neuroimaging abnormalities (2018) (22)
- Using a novel NQO1 bioactivatable drug, beta‐lapachone (ARQ761), to enhance chemotherapeutic effects by metabolic modulation in pancreatic cancer (2017) (20)
- The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity (2021) (20)
- Compartmentalized metabolism supports midgestation mammalian development (2022) (20)
- Metabolic analysis as a driver for discovery, diagnosis, and therapy (2022) (18)
- Does Tumor FDG-PET-Avidity Represent Enhanced Glycolytic Metabolism in Non-Small Cell Lung Cancer? (2019) (18)
- Using arterial–venous analysis to characterize cancer metabolic consumption in patients (2020) (17)
- Isotope tracing reveals glycolysis and oxidative metabolism in childhood tumors of multiple histologies. (2021) (17)
- Stable isotope tracing to assess tumor metabolism in vivo (2021) (17)
- Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness. (2022) (17)
- p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen (2020) (16)
- Genomic regression analysis of coordinated expression (2017) (16)
- The cancer cell ‘energy grid’: TGF-β1 signaling coordinates metabolism for migration (2015) (16)
- EWS-FLI1–regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth (2020) (16)
- Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model (2020) (14)
- In vivo analysis of lung cancer metabolism: nothing like the real thing. (2015) (14)
- Carbon source availability drives nutrient utilization in CD8+ T cells (2022) (14)
- Metabolic Plasticity of Neutrophils: Relevance to Pathogen Responses and Cancer. (2021) (14)
- A male-derived nonribosomal peptide pheromone controls female schistosome development (2022) (14)
- Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells (2022) (13)
- Full-Length L1 Elements Have Arisen Recently in the Same 1-kb Region of the Gorilla and Human Genomes (1998) (13)
- De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma (2022) (13)
- Silencing a Metabolic Oncogene (2013) (12)
- Good neighbours in the tumour stroma reduce oxidative stress (2012) (12)
- The transcription factors aryl hydrocarbon receptor and MYC cooperate in the regulation of cellular metabolism (2020) (11)
- In vivo detection of citrate in brain tumors by 1H magnetic resonance spectroscopy at 3T (2014) (9)
- Active pyruvate dehydrogenase and impaired gluconeogenesis in Orthotopic Hepatomas of rats. (2019) (9)
- Conditions for (13)C NMR detection of 2-hydroxyglutarate in tissue extracts from isocitrate dehydrogenase-mutated gliomas. (2015) (9)
- Concentration-dependent Early Antivascular and Antitumor Effects of Itraconazole in Non–Small Cell Lung Cancer (2020) (9)
- Assessment of Rapid Hepatic Glycogen Synthesis in Humans Using Dynamic 13C Magnetic Resonance Spectroscopy (2020) (8)
- A pathogenic UFSP2 variant in an autosomal recessive form of pediatric neurodevelopmental anomalies and epilepsy (2021) (8)
- A renal cell carcinoma tumorgraft platform to advance precision medicine (2021) (8)
- Vitamin B6-dependent epilepsy due to pyridoxal phosphate-binding protein (PLPBP) defect – First case report from Pakistan and review of literature (2020) (8)
- A mitochondrial power play in lymphoma. (2012) (8)
- Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells (2021) (7)
- In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors (2022) (7)
- Blocking fatty acid synthesis reduces lung tumor growth in mice (2016) (7)
- DiGeorge anomaly in a patient with isochromosome 18p born to a diabetic mother (2005) (7)
- Erratum: An actively retrotransposing, novel subfamily of mouse L1 elements (The EMBO Journal (1998) 17 (590-597)) (2001) (7)
- Hepatic gluconeogenesis influences 13C enrichment in lactate in human brain tumors during metabolism of [1,2-13C]acetate (2016) (7)
- Erratum: NRF2 regulates serine biosynthesis in non–small cell lung cancer (2016) (7)
- Systematic Analysis of Gene Expression in Lung Adenocarcinoma and Squamous Cell Carcinoma with a Case Study of FAM83A and FAM83B (2019) (7)
- Erratum: Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo (Cell Metabolism (2012) 16 (394-406)) (2012) (6)
- Clinically relevant T cell expansion media activate distinct metabolic programs uncoupled from cellular function (2022) (6)
- Real-Time Estimates of Hepatic Gluconeogenesis 1 Real-Time Detection of Hepatic Gluconeogenic and Glycogenolytic States Using Hyperpolarized [ 2-13 C ] Dihydroxyacetone * (2014) (5)
- Hydrophilic interaction liquid chromatography coupled with MS/MS to detect and quantify dicarboxyethyl glutathione, a metabolic biomarker of the fumarate hydratase deficient cancer cell. (2013) (5)
- SNAT7 regulates mTORC1 via macropinocytosis (2022) (5)
- Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2–dependent glutaminolysis pathway (2022) (5)
- Erratum: Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma (2016) (5)
- Proliferating Cells Conserve Nitrogen to Support Growth. (2016) (5)
- Differential requirements for mitochondrial electron transport chain components in the adult murine liver (2021) (5)
- Carbon-13 nuclear magnetic resonance for analysis of metabolic pathways (2010) (4)
- Metabolism: Growth in the fat lane (2015) (4)
- Targeting acetylcholine signaling modulates persistent drug tolerance in EGFR-mutant lung cancer and impedes tumor relapse (2022) (4)
- Mitochondrial enzyme GPT2 regulates metabolic mechanisms required for neuron growth and motor function in vivo. (2021) (4)
- Detection of glucose-derived d- and l-lactate in cancer cells by the use of a chiral NMR shift reagent (2021) (4)
- 2010 Keystone Symposium: Metabolism and Cancer Progression. (2010) (4)
- Targeting BCAT1 combined with α-ketoglutarate triggers metabolic synthetic lethality in glioblastoma. (2022) (4)
- Metabolism of Cell Growth and Proliferation (2008) (4)
- α-ketobutyrate links alterations in cystine metabolism to glucose oxidation in mtDNA mutant cells (2020) (4)
- Leveraging insights into cancer metabolism—a symposium report (2019) (3)
- Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (2019) (3)
- Metabolic impact of pathogenic variants in the mitochondrial glutamyl‐tRNA synthetase EARS2 (2021) (3)
- Q&A: Targeting metabolism to diagnose and treat cancer (2014) (3)
- DDRE-29. DE NOVO PYRIMIDINE SYNTHESIS IS A TARGETABLE VULNERABILITY IN IDH-MUTANT GLIOMA (2021) (3)
- Metabolic vulnerability in tumours illuminated (2019) (3)
- Real-time Detection of Hepatic Gluconeogenic and Glycogenolytic States Using Hyperpolarized (2014) (3)
- In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma (2022) (2)
- A Pan-Cancer Assessment of RB1/TP53 Co-Mutations (2022) (2)
- Abstract 2806: Oxidative stress limits metastasis of human melanoma cells (2016) (2)
- Metabolic heterogeneity in cancer (2014) (2)
- MCT 4 Defines a Glycolytic Subtype of Pancreatic Cancer with Poor Prognosis and Unique Metabolic Dependencies Graphical (2014) (2)
- RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells (2018) (2)
- Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers. (2021) (2)
- Mechanical regulation of glycolysis via cytoskeleton architecture (2020) (2)
- From “N of 1” to N of more (2015) (2)
- Liposuction: Extracellular Fat Removal Promotes Proliferation. (2016) (2)
- Principles of reproducible metabolite profiling of enriched lymphocytes in tumors and ascites from human ovarian cancer (2022) (2)
- Assessing consistency across functional screening datasets in cancer cells (2021) (2)
- Engineering approaches to study cancer metabolism. (2017) (2)
- Targeting the metabolic flexibility of cancer cells: Straighten up and die right (2011) (2)
- Molecular characterization of Pfeiffer syndrome: Implications for prognosis and genetic counseling. (2003) (2)
- Abstract 965: An oncogenic metabolic switch mediates resistance to NOTCH1 inhibition in T-ALL (2014) (1)
- Author response: Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria (2020) (1)
- Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma (2020) (1)
- G6PD deficiency sensitizes metastasizing melanoma cells to oxidative stress and glutaminolysis (2021) (1)
- Adipocytes reprogram glucose metabolism in cancer cells promoting metastasis (2022) (1)
- Obesity is associated with altered tumor metabolism in metastatic melanoma. (2022) (1)
- The hexosamine biosynthesis pathway is a targetable liability in lung cancers with concurrent KRAS and LKB1 mutations (2020) (1)
- Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples (2022) (1)
- Metabolic Pathway Analysis in Cancer (2013) (1)
- Author response: Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria (2020) (1)
- Methodologies for Metabolomics: Carbon-13 Nuclear Magnetic Resonance for Analysis of Metabolic Pathways (2013) (1)
- In vivo detection of IDH mutations in gliomas by 1 H-MRS (2010) (1)
- Abstract 4710: Evaluation of the glutaminase inhibitor CB-839 in non-small cell lung cancer (2015) (1)
- Erratum to: The Hypoxic Epicardial and Subepicardial Microenvironment (2012) (1)
- "Reversed" Krebs cycle can feed tumors. (2012) (1)
- The anti-angiogenic compound dimethyl fumarate inhibits the serine synthesis pathway and increases glycolysis in endothelial cells (2021) (1)
- Glioblastoma cellsrequire glutamate dehydrogenase to survive impairments of glucose metabolism or akt signaling (Cancer Research (2009) 69, (7986-7993)) (2010) (1)
- Analysis of Mitochondrial Metabolism in Cancer Cells by Combining Hyperpolarization and Isotopomer Analysis (2010) (1)
- Precision mapping of the mouse brain metabolome (2020) (1)
- Clinically-relevant T cell expansion protocols activate distinct cellular metabolic programs and phenotypes (2021) (1)
- Reductive carboxylation mediated oxidative stress defense supports anchorage independent cell growth (2014) (1)
- Abstract 308: Reductive Carboxylation Contributes to Cardiac Adaptation in Response to the Oncometabolite D2-hydroxyglutarate (2020) (1)
- Abstract 4614: β-lapachone suppresses glucose metabolism in a NQO1-dependent, tumor-selective manner. (2013) (1)
- Abstract C42: Mitochondrial glutaminase regulation and small molecule inhibition of glutamine metabolism (2013) (1)
- Medical and Neuro-Oncology (2010) (1)
- Metabolon formation regulates branched-chain amino acid oxidation and homeostasis (2022) (1)
- Metabolic changes in cancer cells upon suppression of MYC (2013) (1)
- Abstract 3344: Inhibiting base excision repair synergistically enhances beta-lapachone-mediated ‘kiss of death’ for tumor-selective therapy of pancreatic cancer. (2013) (1)
- Identifying metabolomic features that predict metastasis of melanoma from a primary site (2014) (1)
- Abstract 53: Epigenetic silencing of krebs cycle metabolism in kidney cancer (2016) (1)
- Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance (2022) (1)
- Abstract IA08: Oxidative stress inhibits distant metastasis by human melanoma cells (2016) (1)
- Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells. (2022) (1)
- N-Acetyl Cysteine Abrogates Silver-Induced Reactive Oxygen Species in Human Cells Without Altering Silver-based Antimicrobial Activity (2019) (1)
- The Role of Altered Metabolic States in Cancer and Other Human Diseases (2018) (0)
- Abstract SY26-01: Mitochondrial metabolism in the survival and growth of cancer cells (2011) (0)
- Genetic Mouse Models (GEMMS) (2018) (0)
- Hypoxic metabolism in human hematopoietic stem cells (2015) (0)
- Decision letter: Underlying dyslipidemia postpartum in women with a recent GDM pregnancy who develop type 2 diabetes (2020) (0)
- Abstract 3685: Targeting a novel cell surface serine protease TMPRSS11B for lung cancer therapy (2023) (0)
- Enhancement of 2-hydroxyglutarate detectability by triple-refocusing difference editing at 3 T in vivo (2012) (0)
- Abstract 5714: Targeting serine metabolism impairs tumor growth in preclinical models of Ewing sarcoma (2020) (0)
- Metabolic outliers in human disease (2022) (0)
- Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer (2021) (0)
- Multi-echo time approach for study of metabolic profiles in brain tumors at 3T (2010) (0)
- Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency (2022) (0)
- Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers (2023) (0)
- Decision letter: Restored TDCA and valine levels imitate the effects of bariatric surgery (2020) (0)
- P1.03-020 FDG-PET SUVmax Does Not Correlate with Glucose Metabolism in Non-Small Cell Lung Cancer: Topic: Radiology (2017) (0)
- Metabolic heterogeneity confers differences in melanoma metastatic potential (2019) (0)
- Improving PET Evaluation of Brain Tumors. (2015) (0)
- 725 Epidermal deletion of Glut1 highlights essential roles for glucose metabolism in wound healing and the response to UVB irradiation (2017) (0)
- Abstract 787: DNA repair and metabolism inhibitors are tumor-selective when combined with NQO1 bioactivatable drugs for therapy against pancreatic and nonsmall cell lung cancers (2014) (0)
- Abstract 1155: Regulation of glutamine metabolism: Allosteric activation and inhibition of mitochondrial glutaminase (2015) (0)
- A08 MYC-Driven SCLC Has Unique Metabolic Vulnerabilities (2020) (0)
- Mitochondrial pyruvate supports lymphoma proliferation by fueling a non-canonical glutamine metabolism pathway (2022) (0)
- HEMATOPOIESIS AND STEM CELLS Pro fi lin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow (2014) (0)
- Xiaoye hematopoietic stem cells in bone marrow Profilin 1 is essential for retention and metabolism of mouse (2014) (0)
- Decision letter: Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma (2018) (0)
- Using arterial–venous analysis to characterize cancer metabolic consumption in patients (2020) (0)
- L-2-hydroxyglutaric aciduria – review of literature and case series (2023) (0)
- MCT4-Dependent Lactate Secretion Suppresses Antitumor Immunity in LKB1-Deficient NSCLC (2022) (0)
- Abstract B04: NRF2 regulates serine biosynthesis in pancreatic ductal adenocarcinoma (2016) (0)
- IgE Cross-Linking Downregulates Expression of Glycolytic Genes in Human Plasmacytoid Dendritic Cells (2012) (0)
- 669 In vivo characterization of melanoma metabolism in human patients through intraoperative [U-13C] glucose infusions (2021) (0)
- Abstract SY02-01: Understanding metabolic phenotypes in human tumors (2017) (0)
- Integrated Metabolic Profiling and Gene Expression Analysis Reveals Therapeutic Modalities in Breast Cancer (2020) (0)
- Genomic regression analysis of coordinated expression (2017) (0)
- Decision letter: Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice (2019) (0)
- Abstract 271: MYC mediates enhanced lactate reutilization and resistance to anti-angiogenesis therapy in preclinical models of LKB1-deficient NSCLC (2023) (0)
- Reductive carboxylation mediated oxidative stress defense supports anchorage independent cell growth (2014) (0)
- Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells (2021) (0)
- Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis (2018) (0)
- Metabolic heterogeneity in cancer (2014) (0)
- Abstract #4413: The role of fatty acid desaturation in tumor cell proliferation. (2009) (0)
- T-cell therapy targets glioblastoma. (2015) (0)
- Decision letter: Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability (2019) (0)
- Relationship Between Neuroendocrine and Immune Gene Expression in Small Cell Lung Cancer (2020) (0)
- Integrated Systems and Technologies A Novel Radiotracer to Image Glycogen Metabolism in Tumors by Positron Emission Tomography (2014) (0)
- 521 Immune regulatory metabolites in human ovarian cancer (2020) (0)
- Quantitative Proteomic and Transcriptomic Analysis Reveals Post-Transcriptional Regulation of Mitochondrial Biogenesis during Erythropoiesis (2015) (0)
- Targeting Disease through Metabolism (2016) (0)
- Metabolic Adjustments following Glutaminase Inhibition by CB-839 in Glioblastoma Cell Lines (2023) (0)
- Science Journals — AAAS (2016) (0)
- Cellular ultrastructures as key to understanding tumor in situ energy metabolism : biological significance of the Warburg effect (2017) (0)
- Retrotransposition and evolution of L1 sequences in mammalian genomes (1998) (0)
- Amelioration Of Cytotoxic And Metabolic Effects Of Silver Cations On Respiratory Epithelial Cells By N-Acetyl Cysteine (2011) (0)
- Profiling Carbohydrate Metabolism in Liver and Hepatocellular Carcinoma with [13C]-Glycerate Probes. (2021) (0)
- Abstract 6572: A lung cancer cell line explorer (2023) (0)
- 2-Hydroxyglutarate in Gliomas with IDH Gene Mutation Using High Resolution 1 H-NMR Spectroscopy of Tissue Extracts (2011) (0)
- Mitochondrial metabolism in primary and metastatic human kidney cancers (2023) (0)
- Citrate increases in gliomas in adult patients , as measured by 1 H-MRS at 3 T in vivo (2012) (0)
- Mitochondrial fatty acid synthesis: not just another way to make fatty acids (2020) (0)
- Decision letter: Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever (2021) (0)
- M eta-analysis of clinical metabolic profiling studies in cancer : challenges and opportunities (2016) (0)
- Abstract P5-05-01: Metabolite profiling and RNA-seq identifies novel metabolomic-genomic biomarker and therapeutic options for rapidly proliferating breast cancers (2022) (0)
- Mitochondrial fatty acid synthesis coordinates mitochondrial oxidative metabolism (2020) (0)
- Q&A: Targeting metabolism to diagnose and treat cancer (2014) (0)
- Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative magnetic resonance imaging. (2017) (0)
- Abstract IA21: Developing a new functional classification of lung cancer based on tumor acquired vulnerabilities. (2014) (0)
- Clinico-Pathological and Molecular Spectrum of Biotinidase Deficiency- Experience from a Lower Middle-Income Country. (2021) (0)
- Mitochondria Coordinate Intracellular Metabolism and Epigenetic Gene Regulation during Erythropoiesis (2016) (0)
- Mitochondrial NADP+ is essential for proline biosynthesis during cell growth (2021) (0)
- Abstract SY21-01: Analyzing tumor metabolism in patients (2019) (0)
- Pyruvate dehydrogenase activity is required for optimal growth under lipid deficient conditions (2014) (0)
- Measurement of elevated 2-hydroxyglutaric acid in brain tumors by difference editing at 3T in vivo (2011) (0)
- AIF: an acquired metabolic liability in lung cancer (2019) (0)
- Decision letter: Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma (2020) (0)
- Abstract IA21: Metabolic phenotypes and liabilities in human cancer (2020) (0)
- Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity (2019) (0)
- Abstract IA27: MYC drives molecular and therapeutically distinct subtype of SCLC (2018) (0)
- Chronic STING-dependent activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism in mice (2016) (0)
- Abstract 871: KYNU expression is a prognostic factor in KEAP1/STK11 co-mutated lung adenocarcinoma (2021) (0)
- MS32.01 Genetic Mouse Models (GEMMS) (2018) (0)
- Abstract A17: Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth (2016) (0)
- Cancer-specific production of N-acetylaspartate via NAT 8 L overexpression in non-small cell lung cancer and its potential as a circulating biomarker Running Title : Cancer-specific production of N-acetylaspartate in NSCLC (2015) (0)
- Noninvasive quantitation of metabolic flux in cancer cells 1 Simultaneous steady-state and dynamic 13 C NMR can differentiate alternative routes of pyruvate metabolism in living cancer cells * (2013) (0)
- Abstract 245: Glutamine fuels the TCA cycle inVHLandFHmutant renal cell carcinoma (2020) (0)
- EXPANDED NEWBORN SCREENING: A REVIEW FOR THE PEDIATRIC PATHOLOGIST. (2010) (0)
- The small cell lung cancer neuroendocrine transdifferentiation explorer (2022) (0)
- Abstract C16: Mapping synthetic vulnerabilities in non-small cell lung cancer (2013) (0)
- Abstract A23: Reversible metabolic changes in human melanoma cells enable distant metastasis (2016) (0)
- MOLECULAR CANCER THERAPEUTICS | CANCER BIOLOGYAND TRANSLATIONAL STUDIES EWS-FLI1–regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth (2020) (0)
- PI3K-DEPENDENT MODULATION OF CPT1A EXPRESSION REGULATES LIPID METABOLISM DURING HEMATOPOIETIC CELL GROWTH (2006) (0)
- Abstract SY10-01: Understanding metabolic heterogeneity in cancer (2014) (0)
- Abstract IA12: Developing precision medicine-based new lung cancer therapeutics (2018) (0)
- 3089 – ELUCIDATING NEW MECHANISMS OF ACQUIRED RESISTANCE TO IDH INHIBITION BY SATURATION VARIANT SCREENING OF BASE-EDITED LEUKEMIA CELLS (2021) (0)
- FASN-Deficiency Induces a Cytosol-to-Mitochondria Citrate Flux to Mitigate Oxidative Stress During Metastatic Transition (2022) (0)
- Abstract B47: Modulating the NQO1-dependent ‘kiss of death’ mechanism of action of NQO1 bioactivatable drugs (2015) (0)
- Pyruvate dehydrogenase activity is required for optimal growth under lipid deficient conditions (2014) (0)
- Abstract B22: Acyl-CoA synthetase long-chain family member 3 dependent lipid homeostasis is required for mutant KRAS driven lung cancer (2016) (0)
- Abstract IA03: Metabolic heterogeneity in cancer cells and tumors (2016) (0)
- Lkb1 deficiency confers glutamine dependency in polycystic kidney disease (2018) (0)
- Abstract B1-55: Predictive modeling of drug sensitivity in non-small cell lung cancer (2015) (0)
- Abstract 1248: Enhanced glutamine metabolism contributes to docetaxel resistance in DU145 prostate cancer cells (2011) (0)
- Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells (2013) (0)
- 639 Metabolic reprogramming maintains skin integrity in the absence of glucose transport and identifies a therapeutic vulnerability in psoriasiform hyperplasia (2018) (0)
- Dissecting Molecular, Pathological, and Clinical Features Associated with Tumor Neural/Neuroendocrine Heterogeneity (2022) (0)
- Abstract IA23: Metabolic complexity in cancer cells and tumors (2018) (0)
- Metabolic diversity in human non-small cell lung cancer (2014) (0)
- We need to talk about the Warburg effect (2020) (0)
- Metabolomics Profiling of Mouse Oral Squamous Cell Carcinoma (AT 84) after Irradiation Under Normoxia and Hypoxia Conditions (2019) (0)
- Optimized protocol for stable isotope tracing and steady-state metabolomics in mouse HER2+ breast cancer brain metastasis (2022) (0)
- Metabolic Perturbations Include Homocysteine Degradation and Polyamine Synthesis in Pathogenesis of Bronchopulmonary Dysplasia (2019) (0)
- Lactate metabolism is essential in early-onset mitochondrial myopathy (2023) (0)
- Hypoxia is a common finding in advanced human tumors and is often associated with metastatic dissemination and poor prognosis (2014) (0)
- Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells (2015) (0)
- Abstract PR003: OXPHOS impairing mitochondrial DNA mutations suppress melanoma growth and metastatic progression (2023) (0)
- Abstract IA07: Metabolic heterogeneity in cancer cells and tumors (2016) (0)
- A comparative study of neuroendocrine heterogeneity in SCLC and NBL (2022) (0)
- An actively retrotransposing, novel subfamily of mouse L1 elements (2013) (0)
- A tribute to Beth Levine (1960-2020). (2020) (0)
- Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
- A non-canonical convergence of carbohydrate and glutamine metabolism is required after metabolic rewiring in 3D environment (2021) (0)
- Targeting Cell Adhesion Molecules in IDH Mutant Myeloid Malignances (2022) (0)
- 3160 – METABOLIC REWIRING IN AML-INITIATING CELLS CREATES A SELECTIVE DEPENDENCY ON BCAA METABOLISM (2022) (0)
- FDA approved drugs with antiviral activity against SARS-CoV-2: From structure-based repurposing to host-specific mechanisms (2023) (0)
- Conditions for 13 C NMR Detection of 2-Hydroxyglutarate in Tissue Extracts from IDH-Mutated Gliomas (2015) (0)
- Integrated Metabolic and Gene Expression Profiling Reveals New Therapeutic Modalities for Rapidly Proliferating Breast Cancers (2021) (0)
- Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (2019) (0)
- Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation (2019) (0)
- Identification of FDA Approved Drugs with Antiviral Activity against SARS-CoV-2: A Tale from structure-based drug repurposing to host-cell mechanistic investigation (2023) (0)
- Evidence for an alternative fatty acid desaturation pathway that increases 1 metabolic plasticity in cancer cells 2 (2019) (0)
- Detection of glucose-derived d- and l-lactate in cancer cells by the use of a chiral NMR shift reagent (2021) (0)
- Abstract A35: Cytosolic reductive carboxylation is required for mitochondrial redox homeostasis during anchorage-independent cell growth (2016) (0)
- FASN-deficiency induces a cytosol-to-mitochondria citrate flux to mitigate detachment-induced oxidative stress (2023) (0)
- Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone (2015) (0)
- Abstract 4708: Mammalian glutamine metabolism controls circadian rhythm through regulation of reactive oxygen species (2015) (0)
- Identifying metabolomic features that predict metastasis of melanoma from a primary site (2014) (0)
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