Ralph L. Brinster | Academic Influence

Ralph L. Brinster's AcademicInfluence.com Rankings

Ralph L. Brinster

Biology

#538

World Rank

#947

Historical Rank

#310

USA Rank

Genetics

#86

World Rank

#121

Historical Rank

#56

USA Rank

biology Degrees

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Biology

Ralph L. Brinster's Degrees

Bachelors Animal Science Rutgers University

Why Is Ralph L. Brinster Influential?

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According to Wikipedia, Ralph Lawrence Brinster is an American geneticist, National Medal of Science laureate, and Richard King Mellon Professor of Reproductive Physiology at the School of Veterinary Medicine, University of Pennsylvania.

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Ralph L. Brinster's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice (1985) (1744)
Spermatogenesis following male germ-cell transplantation. (1994) (1485)
Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes (1982) (1303)
Germline transmission of donor haplotype following spermatogonial transplantation. (1994) (1063)
Germ-line transformation of mice. (1986) (1062)
Production of transgenic rabbits, sheep and pigs by microinjection (1985) (1041)
Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. (1985) (963)
Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells. (2004) (888)
Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast (1990) (771)
Introns increase transcriptional efficiency in transgenic mice. (1988) (688)
Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice (1989) (681)
Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs (1981) (676)
Metallothionein-human GH fusion genes stimulate growth of mice. (1983) (669)
Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. (1994) (628)
Replacement of diseased mouse liver by hepatic cell transplantation. (1994) (589)
Transplantation of testis germinal cells into mouse seminiferous tubules. (2003) (556)
THE EFFECT OF CELLS TRANSFERRED INTO THE MOUSE BLASTOCYST ON SUBSEQUENT DEVELOPMENT (1974) (529)
β1- and α6-integrin are surface markers on mouse spermatogonial stem cells (1999) (527)
Heterologous introns can enhance expression of transgenes in mice. (1991) (484)
Transgenic mice harboring SV40 t-antigen genes develop characteristic brain tumors (1984) (478)
Regulation of spermatogonial stem cell self-renewal in mammals. (2008) (478)
Growth enhancement of transgenic mice expressing human insulin-like growth factor I. (1988) (463)
A METHOD FOR IN VITRO CULTIVATION OF MOUSE OVA FROM TWO-CELL TO BLASTOCYST. (1963) (463)
Spermatogonial stem cells share some, but not all, phenotypic and functional characteristics with other stem cells (2003) (461)
Germline Stem Cell Transplantation and Transgenesis (2002) (454)
Abnormal sexual development in transgenic mice chronically expressing Müllerian inhibiting substance (1990) (449)
Insulin-like growth factor I increases brain growth and central nervous system myelination in tTransgenic mice (1993) (433)
Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene (1987) (426)
The germline stem cell niche unit in mammalian testes. (2012) (424)
The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells (1988) (422)
Genetic engineering of livestock. (1989) (409)
Spermatogonial stem cell enrichment by multiparameter selection of mouse testis cells. (2000) (399)
Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene (1991) (396)
Identifying genes important for spermatogonial stem cell self-renewal and survival. (2006) (390)
STUDIES ON THE DEVELOPMENT OF MOUSE EMBRYOS IN VITRO. II. THE EFFECT OF ENERGY SOURCE. (1964) (389)
An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. (1987) (388)
Rat spermatogenesis in mouse testis (1996) (371)
Erythroid‐specific expression of human beta‐globin genes in transgenic mice. (1985) (354)
Genetically haploid spermatids are phenotypically diploid (1989) (348)
A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene. (1984) (347)
Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice. (1990) (347)
Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice. (1987) (346)
Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells (1988) (337)
Pattern and kinetics of mouse donor spermatogonial stem cell colonization in recipient testes. (1999) (334)
Culture Conditions and Single Growth Factors Affect Fate Determination of Mouse Spermatogonial Stem Cells1 (2004) (327)
The effect of thymus environment on T cell development and tolerance (1988) (324)
Transplantation of male germ line stem cells restores fertility in infertile mice (2000) (321)
Reconstitution of spermatogenesis from frozen spermatogonial stem cells (1996) (320)
Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring (1982) (318)
Transgenic mice produced by retroviral transduction of male germ-line stem cells (2001) (312)
Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulinlike growth factor-1. (1988) (311)
Maintenance of Mouse Male Germ Line Stem Cells In Vitro1 (2003) (311)
Dwarf mice produced by genetic ablation of growth hormone-expressing cells. (1988) (307)
Germ cell genotype controls cell cycle during spermatogenesis in the rat. (1998) (302)
Glial Cell Line-derived Neurotrophic Factor Regulation of Genes Essential for Self-renewal of Mouse Spermatogonial Stem Cells Is Dependent on Src Family Kinase Signaling* (2007) (293)
Remodeling of the postnatal mouse testis is accompanied by dramatic changes in stem cell number and niche accessibility (2001) (291)
Colony stimulating factor 1 is an extrinsic stimulator of mouse spermatogonial stem cell self-renewal (2009) (290)
Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice. (1993) (284)
Culture of mouse spermatogonial stem cells. (1998) (275)
Conservation of spermatogonial stem cell self-renewal signaling between mouse and rat. (2005) (274)
A transgenic mouse model of the chronic hepatitis B surface antigen carrier state. (1985) (274)
Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice (1987) (270)
Male Germline Stem Cells: From Mice to Men (2007) (270)
Long-term survival of human spermatogonial stem cells in mouse testes. (2002) (267)
Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth (1985) (265)
Oncogene-induced liver neoplasia in transgenic mice. (1989) (259)
Peripheral tolerance to an islet cell‐specific hemagglutinin transgene affects both CD4+ and CD8+ T cells (1992) (256)
Antigen presenting function of class II MHC expressing pancreatic beta cells (1988) (255)
The dopamine β-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice (1991) (252)
Transplantation of germ cells from rabbits and dogs into mouse testes. (1999) (249)
Spermatogonial stem cells† (2018) (249)
Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice (1986) (247)
T-cell tolerance by clonal anergy in transgenic mice with nonlymphoid expression of MHC class II I–E (1989) (246)
Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice. (1989) (239)
Diversity of alpha-fetoprotein gene expression in mice is generated by a combination of separate enhancer elements. (1987) (239)
In vitro development of mouse oocytes. (1970) (233)
Effects of Aging and Niche Microenvironment on Spermatogonial Stem Cell Self‐Renewal (2006) (232)
MicroRNA-21 regulates the self-renewal of mouse spermatogonial stem cells (2011) (232)
Recipient preparation is critical for spermatogonial transplantation in the rat. (1999) (228)
Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice. (1987) (228)
Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice (1993) (226)
Xenogeneic spermatogenesis following transplantation of hamster germ cells to mouse testes. (1999) (225)
Regulation of metallothionein–thymidine kinase fusion plasmids injected into mouse eggs (1982) (224)
A strain-specific modifier on mouse chromosome 4 controls the methylation of independent transgene loci (1991) (224)
Complete reconstitution of mouse liver with xenogeneic hepatocytes. (1995) (221)
Primate Spermatogonial Stem Cells Colonize Mouse Testes1 (2001) (221)
Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator (1990) (220)
SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice (1985) (219)
Studies on the development of mouse embyros in vitro. II. The effect of energy source (1965) (219)
STUDIES ON THE DEVELOPMENT OF MOUSE EMBRYOS IN VITRO. I. THE EFFECT OF OSMOLARITY AND HYDROGEN ION CONCENTRATION. (1965) (217)
Protamine 3'-untranslated sequences regulate temporal translational control and subcellular localization of growth hormone in spermatids of transgenic mice. (1989) (217)
Dramatic pituitary hyperplasia in transgenic mice expressing a human growth hormone-releasing factor gene. (1988) (217)
Human gamma- to beta-globin gene switching in transgenic mice. (1990) (216)
No simple solution for making transgenic mice (1989) (207)
Specific expression of an elastase–human growth hormone fusion gene in pancreatic acinar cells of transgenic mice (1985) (205)
Spermatid-specific expression of protamine 1 in transgenic mice. (1987) (205)
Expression of insulin-like growth factor I stimulates normal somatic growth in growth hormone-deficient transgenic mice. (1990) (197)
A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice. (1989) (196)
Transgenic mice overexpressing the mouse homoeobox-containing gene Hox-1.4 exhibit abnormal gut development (1989) (195)
Expression of insulin-like growth factor I in transgenic mice with elevated levels of growth hormone is correlated with growth. (1988) (191)
An experimental protocol for fertility preservation in prepubertal boys recently diagnosed with cancer: a report of acceptability and safety. (2010) (191)
Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice (1984) (190)
A novel MHC class II epitope expressed in thymic medulla but not cortex (1989) (188)
A rapid whole-mount staining procedure for nuclei of mammalian embryos (1985) (184)
Glomerular lesions in mice transgenic for growth hormone and insulinlike growth factor-I. I. Relationship between increased glomerular size and mesangial sclerosis. (1990) (178)
Partial correction of murine hereditary growth disorder by germ-line incorporation of a new gene (1984) (176)
Protein content of the mouse embryo during the first five days of development. (1967) (175)
Technology Insight: in vitro culture of spermatogonial stem cells and their potential therapeutic uses (2006) (174)
Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in κ transgenic mice (1984) (173)
Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice (1983) (172)
Prepubertal human spermatogonia and mouse gonocytes share conserved gene expression of germline stem cell regulatory molecules (2009) (171)
Functional analysis of spermatogonial stem cells in Steel and cryptorchid infertile mouse models. (2000) (170)
Glomerular epithelial, mesangial, and endothelial cell lines from transgenic mice. (1988) (168)
Germline and somatic mosaicism in transgenic mice. (1986) (167)
Pancreatic tumor pathogenesis reflects the causative genetic lesion. (1991) (164)
Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice. (1995) (164)
Restoration of Fertility by Germ Cell Transplantation Requires Effective Recipient Preparation1 (2003) (161)
Computer assisted image analysis to assess colonization of recipient seminiferous tubules by spermatogonial stem cells from transgenic donor mice (1999) (159)
Transmission distortion and mosaicism in an unusual transgenic mouse pedigree (1984) (158)
Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice. (1987) (158)
Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells (1989) (156)
Development of porcine ova that were centrifuged to permit visualization of pronuclei and nuclei. (1985) (156)
Phenotypic and functional characteristics of spermatogonial stem cells in rats. (2004) (147)
Peripheral neuropathies, hepatocellular carcinomas and islet cell adenomas in transgenic mice (1985) (146)
Studies on the development of mouse embryos in vitro. IV. Interaction of energy sources. (1965) (146)
Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver (1993) (142)
beta1- and alpha6-integrin are surface markers on mouse spermatogonial stem cells. (1999) (141)
Oxygen consumption of preimplantation mouse embryos (1967) (135)
Growth allometry of the organs in giant transgenic mice. (1987) (135)
Restoration of Spermatogenesis in Infertile Mice by Sertoli Cell Transplantation1 (2003) (132)
Development of Mouse Embryos in Organ Cultures of Fallopian Tubes on A Chemically Defined Medium (1962) (132)
Development of eight-cell mouse embryos in vitro. (1966) (132)
STUDIES ON THE DEVELOPMENT OF MOUSE EMBRYOS IN VITRO. 3. THE EFFECT OF FIXED-NITROGEN SOURCE. (1965) (132)
Transgenic mice selectively lacking MHC class II (I-E) antigen expression on B cells: An in vivo approach to investigate la gene function (1987) (130)
Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains [published erratum appears in J Exp Med 1989 Jun 1;169(6):2269] (1988) (125)
Fertile offspring derived from mouse spermatogonial stem cells cryopreserved for more than 14 years. (2012) (124)
Human sickle hemoglobin in transgenic mice. (1990) (123)
Transgenic mice with mu and kappa genes encoding antiphosphorylcholine antibodies (1986) (121)
Carbon dioxide production from glucose by the preimplantation mouse embryo. (1967) (120)
Glomerulosclerosis and renal cysts in mice transgenic for the early region of SV40. (1987) (119)
A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes. (1997) (119)
Directed expression of an oncogene to Sertoli cells in transgenic mice using mullerian inhibiting substance regulatory sequences. (1992) (116)
Induction of mouse metallothionein-I mRNA by bacterial endotoxin is independent of metals and glucocorticoid hormones. (1984) (116)
Targeted correction of a major histocompatibility class II E alpha gene by DNA microinjected into mouse eggs. (1989) (113)
Developmental regulation of alpha-fetoprotein genes in transgenic mice (1985) (112)
Development of germ cell transplants in mice. (1998) (111)
P0 promoter directs expression of reporter and toxin genes to schwann cells of transgenic mice (1992) (110)
Expression of the chicken transferrin gene in transgenic mice (1983) (109)
Culture of rodent spermatogonial stem cells, male germline stem cells of the postnatal animal. (2008) (108)
Somatic hypermutation of an immunoglobulin transgene in K transgenic mice (1987) (107)
Ultrastructural observations of spermatogenesis following transplantation of rat testis cells into mouse seminiferous tubules. (1996) (106)
Analysis of the mouse protamine 1 promoter in transgenic mice. (1993) (105)
Stem cell and niche development in the postnatal rat testis. (2003) (104)
The sensitivity of one-cell mouse embryos to pyruvate and lactate. (1973) (104)
Novel developmental specificity in the nervous system of transgenic animals expressing growth hormone fusion genes (1985) (104)
Synthesis of functional human hemoglobin in transgenic mice. (1989) (103)
Infertility in male transgenic mice: disruption of sperm development by HSV-tk expression in postmeiotic germ cells. (1990) (103)
Expression of NGF in sympathetic neurons leads to excessive axon outgrowth from ganglia but decreased terminal innervation within tissues (1993) (102)
Lactate dehydrogenase activity in the preimplanted mouse embryo. (1965) (102)
Immortalized differentiated hepatocyte lines derived from transgenic mice harboring SV40 T-antigen genes. (1988) (101)
Spermatogonial stem cell transplantation, cryopreservation and culture. (1998) (99)
High expression of cloned immunoglobulin k gene in transgenic mice is restricted to B lymphocytes (1984) (99)
Elastase I promoter directs expression of human growth hormone and SV40 T antigen genes to pancreatic acinar cells in transgenic mice. (1985) (99)
Sequences 5' of the homeobox of the Hox-1.4 gene direct tissue-specific expression of lacZ during mouse development. (1993) (98)
Spermatogonial transplantation and reconstitution of donor cell spermatogenesis in recipient mice (1998) (97)
Uptake and incorporation of amino acids by the preimplantation mouse embryo. (1971) (95)
Spermatogonial Stem Cell Self-Renewal Requires ETV5-Mediated Downstream Activation of Brachyury in Mice1 (2011) (94)
Regulation of Mouse Spermatogonial Stem Cell Differentiation by STAT3 Signaling1 (2010) (93)
Efficient generation of transgenic rats through the male germline using lentiviral transduction and transplantation of spermatogonial stem cells. (2006) (92)
Male germ-line stem cell potential is predicted by morphology of cells in neonatal rat testes (2002) (91)
Use of gene transfer to increase animal growth. (1985) (91)
Functional Analysis of Stem Cells in the Adult Rat Testis1 (2002) (91)
The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice (1987) (91)
Heart and bone tumors in transgenic mice. (1988) (91)
Spermatogonial stem cells. (2006) (89)
Progress on gene transfer in farm animals. (1987) (89)
Clonal deletion of V beta 5+ T cells by transgenic I-E restricted to thymic medullary epithelium. (1993) (88)
The POU Domain Transcription Factor POU3F1 Is an Important Intrinsic Regulator of GDNF-Induced Survival and Self-Renewal of Mouse Spermatogonial Stem Cells1 (2010) (88)
Tissue-specific posttranslational processing of pre-prosomatostatin encoded by a metallothionein-somatostatin fusion gene in transgenic mice (1985) (88)
Lentiviral vector transduction of male germ line stem cells in mice (2002) (87)
Germ Line Stem Cell Competition in Postnatal Mouse Testes1 (2002) (86)
Poly(A) and synthesis of polyadenylated RNA in the preimplantation mouse embryo. (1978) (85)
Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice. (1991) (85)
Lactate dehydrogenase isozymes in the early mouse embryo. (1967) (84)
Immortalized retinal neurons derived from SV40 T-antigen-induced tumors in transgenic mice (1990) (84)
Leuprolide, a gonadotropin-releasing hormone agonist, enhances colonization after spermatogonial transplantation into mouse testes. (1998) (83)
Transgenic mice express the human phenylethanolamine N-methyltransferase gene in adrenal medulla and retina. (1988) (81)
DIFFERENTIAL IMMUNOFLUORESCENCE OF FERTILIZED MOUSE EGGS WITH H-2 AND NON H-2 ANTIBODY (1971) (80)
Testicular tissue cryopreservation in prepubertal male children: An analysis of parental decision‐making (2014) (79)
Embryo development. (1974) (79)
Cell-specific expression from the human dopamine beta-hydroxylase promoter in transgenic mice is controlled via a combination of positive and negative regulatory elements (1994) (79)
Introduction of genes into the germ line of animals. (1984) (77)
Retrovirus-Mediated Modification of Male Germline Stem Cells in Rats1 (2002) (76)
Some neuronal cell populations express human dopamine β-hydroxylase-lacZ transgenes transiently during embryonic development (1991) (75)
Expression of mouse IgA by transgenic mice, pigs and sheep (1991) (75)
Glial cell line‐derived neurotrophic factor and endothelial cells promote self‐renewal of rabbit germ cells with spermatogonial stem cell properties (2011) (71)
Leukemia inhibitory factor induces neurotransmitter switching in transgenic mice. (1994) (70)
Oxidation of pyruvate and glucose by oocytes of the mouse and rhesus monkey. (1971) (70)
Expression and performance in transgenic pigs. (2020) (70)
Translation of globin messenger RNA by the mouse ovum (1980) (65)
Ultrastructural observations of spermatogenesis in mice resulting from transplantation of mouse spermatogonia. (1996) (64)
7 – CULTIVATION OF THE MAMMALIAN EMBRYO (1972) (62)
Expression from the transferrin gene promoter in transgenic mice (1989) (61)
Genetic engineering of mammalian embryos. (1986) (61)
BIOMETRICAL PROBLEMS IN THE STUDY OF EARLY MAMMALIAN EMBRYOS IN VITRO. (1965) (60)
Glucose 6-phosphate-dehydrogenase activity in the preimplantation mouse embryo. (1966) (59)
Regulation of fat and muscle development by transforming growth factor alpha in transgenic mice and in cultured cells. (1993) (59)
High-level erythroid expression of human alpha-globin genes in transgenic mice. (1989) (59)
Differential expression of α-fetoprotein genes on the inactive X chromosome in extraembryonic and somatic tissues of a transgenic mouse line (1986) (58)
Integration, expression and germ-line transmission of growth-related genes in pigs. (1990) (57)
Hexokinase activity in the preimplantation mouse embryo. (1968) (56)
Effect of the GnRH-agonist leuprolide on colonization of recipient testes by donor spermatogonial stem cells after transplantation in mice. (2001) (56)
Tissue‐specific, inducible and functional expression of the E alpha d MHC class II gene in transgenic mice. (1985) (56)
Synthesis of tubulin and actin during the preimplantation development of the mouse. (1978) (55)
Expression of human metallothionein-III in transgenic mice (1995) (52)
Carbon dioxide production from lactate and pyruvate by the preimplantation mouse embryo. (1967) (51)
Protein metabolism in preimplanted mouse ova. (1976) (51)
Expression of human HPRT in the central nervous system of transgenic mice (1985) (50)
Incorporation of carbon from glucose and pyruvate into the preimplantation mouse embryo. (1969) (50)
Energy metabolism in primordial germ cells of the mouse. (1977) (50)
Expression of human or bovine growth hormone gene with a mouse metallothionein-1 promoter in transgenic swine alters the secretion of porcine growth hormone and insulin-like growth factor-I. (1989) (50)
Enrichment and transplantation of spermatogonial stem cells. (2000) (50)
In vitro culture of mammalian embryos. (1968) (50)
Simian virus 40 (SV40)-transgenic mice that develop tumors are specifically tolerant to SV40 T antigen (1987) (50)
Expression of a mouse Zfy-1/lacZ transgene in the somatic cells of the embryonic gonad and germ cells of the adult testis. (1994) (49)
Oncogene expression in retinal horizontal cells of transgenic mice results in a cascade of neurodegeneration (1993) (49)
Ig lambda-producing B cells do not show feedback inhibition of gene rearrangement. (1988) (49)
In vitro cultivation of mammalian ova. (1970) (46)
Protein degradation during preimplantation development of the mouse. (1981) (46)
Spermatogonial Stem Cells Derived from Infertile Wv/Wv Mice Self-Renew In Vitro and Generate Progeny Following Transplantation1 (2009) (46)
Requirements for blastocyst development in vitro. (1979) (46)
Ectopic expression of metallothionein-III causes pancreatic acinar cell necrosis in transgenic mice. (1998) (45)
Transferrin- and albumin-directed expression of growth-related peptides in transgenic sheep. (1991) (44)
Transgenic mice (1985) (44)
Relative growth of the skull and postcranium in giant transgenic mice. (1990) (44)
A recessive defect in lymphocyte or granulocyte function caused by an integrated transgene. (1992) (44)
Gonadotroph-specific expression of metallothionein fusion genes in pituitaries of transgenic mice. (1986) (44)
Identification of Glial Cell Line-Derived Neurotrophic Factor-Regulated Genes Important for Spermatogonial Stem Cell Self-Renewal in the Rat1 (2009) (43)
A chicken transferrin gene in transgenic mice escapes X-chromosome inactivation. (1987) (43)
Mouse oocytes transcribe injected Xenopus 5S RNA gene. (1981) (43)
Influence of reduced glucose levels on the in vitro hatching, attachment, and trophoblast outgrowth of the mouse blastocyst. (1976) (42)
DNA rearrangement causes hepatocarcinogenesis in albumin-plasminogen activator transgenic mice. (1992) (42)
Immunohistochemical analysis of human growth hormone-releasing hormone gene expression in transgenic mice. (1989) (42)
Histology of Testicular Biopsies Obtained for Experimental Fertility Preservation Protocol in Boys with Cancer. (2015) (42)
Effects of α-amanitin on RNA synthesis by mouse embryos in culture (1978) (40)
Metallothionein-vasopressin fusion gene expression in transgenic mice. Nephrogenic diabetes insipidus and brain transcripts localized to magnocellular neurons. (1989) (39)
Glycogen content of preimplantation mouse embryos (1966) (39)
Active chloride transport in the isolated rabbit oviduct. (1971) (39)
Effects of alpha-amanitin on the development of mouse ova in culture. (1977) (38)
Induced chimaerism by transplanting embryonic cells into mouse blastocysts. (1972) (38)
Leucine uptake and incorporation at three stages of mouse oocyte maturation. (1974) (37)
Culture of two-cell rabbit embryos to morulae. (1970) (36)
Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene [published erratum appears in J Exp Med 1989 Aug 1;170(2):619] (1989) (36)
Changes in membrane potential during mouse egg development. (1973) (35)
Protein degradation in the mouse blastocyst. (1979) (35)
Expression of an avian protamine in transgenic mice disrupts chromatin structure in spermatozoa. (1995) (34)
Malic dehydrogenase activity in the preimplantation mouse embryo. (1966) (34)
Genes Involved in Post‐Transcriptional Regulation Are Overrepresented in Stem/Progenitor Spermatogonia of Cryptorchid Mouse Testes (2008) (33)
Expression, Allelic Exclusion and Somatic Mutation of Mouse Immunoglobulin Kappa Genes (1986) (32)
A C/EBP-binding site in the transferrin promoter is essential for expression in the liver but not the brain of transgenic mice (1993) (32)
Carbon dioxide production from glucose by the preimplantation rabbit embryo. (1968) (31)
The uptake of hexoses by pre-implantation mouse embryos in vitro. (1968) (31)
Promoter and enhancer elements from the rat elastase I gene function independently of each other and of heterologous enhancers (1987) (30)
Pulmonary carcinogenesis in transgenic mice. (1991) (29)
Participation of teratocarcinoma cells in mouse embryo development. (1976) (29)
Expression of creatine kinase isoenzyme during oogenesis and embryogenesis in the mouse. (1983) (29)
In-vitro fertilization of mouse ova within the explanted fallopian tube. (1965) (29)
Radioactive carbon dioxide production from pyruvate and lactate by the preimplantation rabbit embryo. (1969) (29)
Expression of human beta-globin genes in transgenic mice: effects of a flanking metallothionein-human growth hormone fusion gene (1985) (28)
Effect of glutathione on the development of two-cell mouse embryos in vitro. (1968) (27)
Stem cells and transgenic mice in the study of development. (1993) (27)
Pre-B cells in κ-transgenic mice (1985) (26)
The fate of transplanted cells in mouse blastocysts in vitro. (1972) (26)
Insertion, expression and physiology of growth-regulating genes in ruminants. (1990) (26)
Regulated Expression of α-Fetoprotein Genes in Transgenic Mice (1985) (26)
Influence of ions, inhibitors and anoxia on transtrophoblast potential of rabbit blastocyst. (1970) (26)
Expression of Mouse Protamine 1 Genes in Transgenic Mice a (1989) (25)
Developmental study of SV40 large T antigen expression in transgenic mice with choroid plexus neoplasia. (1988) (25)
In Vivo and In Vitro Aging Is Detrimental to Mouse Spermatogonial Stem Cell Function1 (2011) (25)
INSERTION OF GROWTH HORMONE GENES INTO PIG EMBRYOS (1989) (24)
Rabbit α-globin messenger RNA translation by the mouse ovum (1983) (24)
Developmental Regulation of ox-Fetoprotein Genes in Transgenic Mice (24)
Tissue distribution and molecular heterogeneity of human growth hormone-releasing factor in the transgenic mouse. (1990) (22)
Translation and stability of ovalbumin messenger RNA injected into growing oocytes and fertilized ova of mice. (1984) (22)
Development of germ cell transplants: morphometric and ultrastructural studies. (1999) (22)
Lactic Dehydrogenase Activity in Preimplantation Rat Embryo (1967) (21)
Lactate dehydrogenase isozymes in mouse blastocyst cultures. (1968) (21)
Carbon dioxide production from pyruvate and glucose by bovine oocytes. (1973) (21)
Histologic Characterization of Hepatic Carcinogenesis in Transgenic Mice Expressing SV40 T-antigens (1993) (21)
Lactate dehydrogenase activity in the preimplantion rabbit embryo (1967) (21)
Selective expression of class II E alpha d gene in transgenic mice. (1989) (21)
DNase I super-hypersensitive sites direct high level erythroid expression of human alpha-, beta- and beta s- globin genes in transgenic mice. (1989) (20)
FGF9 promotes mouse spermatogonial stem cell proliferation mediated by p38 MAPK signalling (2020) (20)
Lactate dehydrogenase activity in the oocytes of mammals. (1968) (20)
Chemokine (C-X-C) Ligand 12 Facilitates Trafficking of Donor Spermatogonial Stem Cells (2016) (20)
Estrogen regulation of the avian transferrin gene in transgenic mice (1986) (19)
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. 1982. (1992) (19)
Tumorigenesis in transgenic mice by a nuclear transport-defective SV40 large T-antigen gene. (1987) (18)
Odontogenic tumors in mice carrying albumin-myc and albumin-ras transgenes (1992) (18)
Elevation of 1,2-diacylglycerol in ras-transformed neonatal liver and pancreas of transgenic mice. (1989) (18)
Parental glucose phosphate isomerase activity in three-day mouse embryos (1973) (17)
RESEARCH BRIEFS (2017) (17)
Trans membrane potential of the rabbit blastocyst trophoblast. (1969) (17)
Cloning of a gamma 2b gene encoding anti-Pseudomonas aeruginosa H chains and its introduction into the germ line of mice. (1988) (17)
Spermatogonial Stem Cell Transplantation to the Testis. (2017) (16)
β-AND α 6- INTEGRINES ARE SURFACE MARKERS ON MOUSE SPERMATOGONIAL STEM CELLS (1999) (16)
Tissue‐specific Expression of Pancreatic Genes in Transgenic Mice a (1986) (16)
Induction of foreign genes in animals (1982) (16)
Somatostatin is targeted to the regulated secretory pathway of gonadotrophs in transgenic mice expressing a metallothionein-somatostatin gene. (1986) (16)
Stimulation of growth hormone synthesis by glucose in islets of Langerhans isolated from transgenic mice. (1986) (15)
Female Mice Delay Reproductive Aging in Males1 (2009) (15)
In Vivo and In Vitro Aging Is Detrimental to Mouse Spermatogonial Stem Cell Function 1 (2011) (15)
Alteration of neurotransmitter phenotype in noradrenergic neurons of transgenic mice. (1992) (15)
Metabolism of the Ovum Between Conception and Nidation (1970) (14)
Changes in protein synthesis following fertilization of the mouse ovum. (1980) (14)
c-myc-induced lymphomagenesis in transgenic mice and the role of the Pvt-1 locus in lymphoid neoplasia. (1986) (14)
Expression of Immunoglobulin Genes in Transgenic Mice and Transfected Cells a (1988) (14)
Actin and tubulin synthesis in murine blastocyst outgrowths. (1978) (14)
Human 7- to -globin gene switching in transgenic mice (2007) (13)
Insertional mutation at the ld locus (again!) in a line of transgenic mice. (1990) (13)
Embryo culture, stem cells and experimental modification of the embryonic genome. An interview with Professor Ralph Brinster.. Interview by Juan Aréchaga. (1998) (13)
Blastocyst development of mouse pre-implantation embryos in the rabbit Fallopian tube. (1969) (12)
Expression of Growth Hormone Genes in Transgenic Mice. (1985) (11)
Lactate dehydrogenase activity in the preimplantation rabbit embryo. (1967) (10)
Secretion of protein by the fertilized mouse ovum. (1981) (10)
Transgenic progeny inherit tissue-specific expression of rat elastase I genes. (1986) (10)
Synthesis and secretion of ovalbumin by mouse-growing oocytes following microinjection of chick ovalbumin mRNA. (1983) (9)
Transgenic mice containing growth hormone fusion genes. (1984) (9)
The myc oncogene and lymphoid neoplasia: from translocations to transgenic mice. (1987) (9)
Isolation, Cryopreservation, and Transplantation of Spermatogonial Stem Cells. (2019) (8)
Isolation of the Spermatogonial Stem Cell-Containing Fraction from Testes. (2017) (8)
Spermatogonial stem cell spermatogenesis (2000) (8)
Lactate dehydrogenase activity in human, squirrel monkeys, and rhesus monkey oocytes☆ (1967) (8)
Activity of mitochondrial enzymes in mouse embryos. (1973) (8)
Culture and Expansion of Primary Undifferentiated Spermatogonial Stem Cells. (2017) (8)
Effect of bovine growth hormone gene expression, sex and age on plasma gonadotropins, estrone and testosterone in prepuberal pigs. (1991) (8)
Control of Expression of Immunoglobulin Genes (1989) (7)
Effects of alpha-amanitin on RNA synthesis by mouse embryos in culture. (1978) (7)
Glucose 6-phosphate dehydrogenase activity in the early rabbit and mouse embryo (1970) (7)
Lactate dehydrogenase isozymes in the preimplantation rabbit embryo (1973) (7)
SV40 T-antigen is a histocompatibility antigen of SV40-transgenic mice (1988) (7)
I-E transgenic mice: A model system to dissect the regulation and function of MHC class II genes in vivo (1990) (6)
Delay of Early B-Lymphocyte Development by Gamma 2b Immunoglobulin Transgene: Effect on Differentiation-Specific Molecules (1990) (6)
Stability of rabbit globin and its messenger RNA in the mouse ovum. (1982) (5)
SIMIAN VIRUS 40 ( SV 40 )-TRANSGENIC MICE THAT DEVELOP TUMORS ARE SPECIFICALLY TOLERANT TO SV 40 T ANTIGEN (1987) (5)
Transplantation and Culture of Spermatogonial Stem Cells (2017) (5)
Gene insertion: Role and limitations of technique in farm animals as a key to growth (1988) (5)
Roles of Stra8 and Tcerg1l in retinoic acid induced spermatogonial differentiation in mouse (2021) (5)
Cleavage of pig embryos after labeling with fluorescent dyes (1985) (4)
Regulated expression of alpha-fetoprotein genes in transgenic mice. (1985) (4)
Expression of a metallothionein-vasopressin fusion gene in transgenic mice produces hypervasopressinemia and manifestations of nephrogenic diabetes insipidus. (1988) (4)
Antisense oligodeoxynucleoside methylphosphonate inhibition of mouse c-myc p65 protein expression in E mu-c-myc transgenic mice. (1991) (4)
Clonal anergy of I-E-tolerant T cells in transgenic mice with pancreatic expression of MHC class II I-E. (1989) (4)
Tolerance to class II MHC in transgenic mice. (1989) (4)
Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. 1982. (1992) (4)
Title: the Pou Domain Transcription Factor Pou3f1 Is an Important Intrinsic Regulator of Gdnf- Induced Survival and Self-renewal of Mouse Spermatogonial Stem Cells Short Title: Pou3f1 Regulation of Ssc Survival and Self-renewal (2010) (4)
INHIBITION OF IMMUNOGLOBULIN GENE REARRANGEMENT BY THE EXPRESSION OF A A2 TRANSGENE (2003) (4)
Visualization and ablation of phenylethanolamineN-methyltransferase producing cells in transgenic mice (1994) (3)
Germ Cell Transplantation (2014) (3)
Atrial natriuretic peptide synthesis in atrial tumors of transgenic mice. (1992) (3)
Effects of cordycepin on macromolecular synthesis and development in the preimplantation mouse embryo. (1977) (3)
Phosphofructokinase activity in the preimplantation mouse embryo (1971) (3)
Effects of a nonsteroidal antifertility agent (U-11100A) on pregnancy in mice. (1969) (3)
Possible energy sources for the development of the early mouse embryo (1964) (2)
The effect of cells transferred into the mouse blastocyst subsequent development. Abstr. (1974) (2)
Rearrangement and expression of immunoglobulin genes in transgenic mice. (1992) (2)
BRINSTER, ENRICHMENT AND TRANSPLANTATION OF SPERMATOGONIAL STEM CELLS (2000) (2)
Rabbit alpha-globin messenger RNA translation by the mouse ovum. (1983) (2)
De novo pyrimidine nucleotide synthesis in the preimplantation mouse embryo. (1981) (2)
REQUIREMENTS FOR BLASTOCYST DEVELOPMENT (1979) (2)
Studies of the development of mouse embryos in vitro Energy metabolism (2008) (2)
Spermatogonial Stem Cell Transplantation and Culture (2011) (1)
Gene transplants into germ cells. (1987) (1)
Islet endocrine cell MHC antigen expression in allograft rejection. (1990) (1)
The regulation of alpha-foetoprotein minigene expression in the germline of mice. (1986) (1)
Targeted expression of cloned genes in transgenic mice. (1987) (1)
Progressive Gbomeru loscerosis Develops in Transgenic MiceChronically Expressing Growth Hormone andGrowth Hormone Releasing Factor butNotinThose Expressing Insulinlike Growth Factor-i (1988) (1)
Gene transfer for increased animal growth (1988) (1)
Activity of 6-phosphogluconate dehydrogenase in the preimplantation mouse and rabbit embryo (1971) (1)
FUNCTIONAL DECIPHERING OF THE CORE SIGNALING MECHANISM FOR SPERMATOGONIAL STEM CELL SELF-RENEWAL AND SURVIVAL (2007) (1)
Pre-B cells in kappa-transgenic mice. (1985) (1)
Reestablishment of spermatogenesis after more than 20 years of cryopreservation of rat spermatogonial stem cells reveals an important impact in differentiation capacity (2022) (1)
Control of dna sequences-transcriptional. (1982) (0)
1998 Carl G. Hartman Award. (1998) (0)
Positions available (1995) (0)
Short Title: STAT3 regulation of SSC differentiation Summary Sentence: Impairment of STAT3 signaling altered SSC fate decisions leading to a greater rate of self-renewal and blocked spermatogonial differentiation within mouse seminiferous tubules. (2010) (0)
The regulation of α-foetoprotein minigene expression in the germline of mice (1986) (0)
SCHWANN-CEIL-SPECIFIC GENE EXPRESSION IN TRANSGENIC MICE: 138 (1989) (0)
Promoter andEnhancer Elements fromtheRatElastase IGene Function Independently ofEachOtherandofHeterologous Enhancers (1987) (0)
Clonal Anergy in Transgenic Mice with Pancreatic Expression of MHC Class II I-E (1990) (0)
DEVELOPMENTAL STUDY OF SV*** GENE EXPRESSION IN TRANSGENIC MICE WITH DISORDERS OF CHOROID PLEXUS, THYMUS AND KIDNEY: 125 (1987) (0)
Summary Sentence: Reduction of POU3F1 expression in mouse SSCs impairs their self- renewal and survival in vitro; whereas, similar reduction of POU5F1 expression has no effect. (2010) (0)
Spontaneous amyloidosis and renal disease in strain A/Sn mice. (1960) (0)
Short Title: Females delay reproductive aging in males. Summary Sentence: Cohabitation with females during aging dramatically increases the reproductive lifespan of male mice. (2009) (0)
An investigation into the possibility of neuraminidase-like action of salmonella bacteria. (1960) (0)
Short title: Genetic Regulation of SSC self-renewal in rats. Summary sentence: Bcl6b, Etv5, Bhlhe40, Hoxc4, and Tec are glial cell line-derived neurotrophic factor-regulated and important for spermatogonial stem cell self-renewal in the rat. (2009) (0)
High plasma levels of immunoreactive somatostatin in transgenic mice expressing a metallothionein-somatostatin fusion gene. (1984) (0)
Chemokine ( CXC ) Ligand 12 Facilitates Trafficking of Donor Spermatogonial Stem Cells (2016) (0)
TRANSFER OF THE MOUSE METALLOTHIONEIN-I GENE INTO CULTURED CELLS AND INTO ANIMALS (1982) (0)
Multiple sequences regulate human beta-globin gene expression in transgenic mice. (1987) (0)
Spermatogenesis following male germ-cell transplantation ( spermatogonia / stem cd / testes / nsc mice ) (0)
Immunoglobulin Transgene" Effect on Differentiation- Specific Molecules (1990) (0)
Introns increase transcriptional efficiency in transgenic mice ( intervening sequences / gene expression / gene transfer (2003) (0)
Animals aren't drugs (2008) (0)
Scientists and rights (2008) (0)
Transplantation of Cryopreserved Spermatogonia (0)
A Remembrance of Mark and Lila Allam (1998) (0)
Development of Germ Cell Transplants in Mice1 (1998) (0)
United States Patent ( 19 ) Evans et al . ( 54 ) METHOD OF OBTAINING GENE PRODUCT THROUGH THE GENERATION OF TRANSGENIC ANIMALS (2017) (0)
A Transgenic Mouse Model for Human Sickle Cell Disease (1990) (0)
In Vitro Development of Mouse Oocytes1 (2004) (0)
Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice (2019) (0)
Participation of TeratocarcinomaCells in Mouse Embryo Development1 (1976) (0)
Principles and Practice of Fertility Preservation: Transplantation of cryopreserved spermatogonia (2011) (0)
The homeobox, a highly conserved 183 bp sequence found in several classes of development-regulating genes in Drosophila, is also conserved in the genome of organisms as evolutionarily diverse as sea urchins and mammals (1996) (0)
Spermatogonial Transplantation and Spermatogonial Stem Cell Competence (2014) (0)
The Transfer of New Genes into Mice (1984) (0)
Immunologic consequence of class II+ pancreatic islet allografts on recipient responsiveness. (1990) (0)

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