Ralph M. Steinman | Academic Influence

Why Is Ralph M. Steinman Influential?

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According to Wikipedia, Ralph Marvin Steinman was a Canadian physician and medical researcher at Rockefeller University, who in 1973 discovered and named dendritic cells while working as a postdoctoral fellow in the laboratory of Zanvil A. Cohn, also at Rockefeller University. Steinman was one of the recipients of the 2011 Nobel Prize in Physiology or Medicine.

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Ralph M. Steinman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Papers

Dendritic cells and the control of immunity (1998) (15235)
The dendritic cell system and its role in immunogenicity. (1991) (5043)
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor (1992) (4088)
Dendritic Cells Specialized and Regulated Antigen Processing Machines (2001) (2333)
Taking dendritic cells into medicine (2007) (2070)
Proliferating dendritic cell progenitors in human blood (1994) (2064)
Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo (2001) (1973)
Tolerogenic dendritic cells. (2003) (1796)
IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE (1973) (1726)
Antigen-Specific Inhibition of Effector T Cell Function in Humans after Injection of Immature Dendritic Cells (2001) (1503)
Differential Antigen Processing by Dendritic Cell Subsets in Vivo (2007) (1398)
Efficient Targeting of Protein Antigen to the Dendritic Cell Receptor DEC-205 in the Steady State Leads to Antigen Presentation on Major Histocompatibility Complex Class I Products and Peripheral CD8+ T Cell Tolerance (2002) (1348)
Endocytosis and the recycling of plasma membrane (1983) (1347)
The Induction of Tolerance by Dendritic Cells That Have Captured Apoptotic Cells (2000) (1319)
Vaccination with Mage-3a1 Peptide–Pulsed Mature, Monocyte-Derived Dendritic Cells Expands Specific Cytotoxic T Cells and Induces Regression of Some Metastases in Advanced Stage IV Melanoma (1999) (1318)
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance (2002) (1240)
Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro (1985) (1141)
IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE (1974) (1103)
Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells (2002) (1073)
Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. (1999) (1017)
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing (1995) (1017)
Direct Expansion of Functional CD25+ CD4+ Regulatory T Cells by Antigen-processing Dendritic Cells (2003) (995)
Decisions about dendritic cells: past, present, and future. (2012) (994)
In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination (2004) (924)
Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking. (1998) (919)
TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor (1997) (912)
Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine. (2001) (891)
Dendritic cells: translating innate to adaptive immunity. (2006) (885)
DC-SIGN (CD209) Mediates Dengue Virus Infection of Human Dendritic Cells (2003) (846)
Developmental regulation of MHC class II transport in mouse dendritic cells (1997) (841)
Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice. (1978) (796)
CD25+ CD4+ T Cells, Expanded with Dendritic Cells Presenting a Single Autoantigenic Peptide, Suppress Autoimmune Diabetes (2004) (764)
Activation of Natural Killer T Cells by α-Galactosylceramide Rapidly Induces the Full Maturation of Dendritic Cells In Vivo and Thereby Acts as an Adjuvant for Combined CD4 and CD8 T Cell Immunity to a Coadministered Protein (2003) (756)
Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood. (1996) (751)
Interleukin‐12 is produced by dendritic cells and mediates T helper 1 development as well as interferon‐γ production by T helper 1 cells (1996) (734)
Efficient Presentation of Phagocytosed Cellular Fragments on the Major Histocompatibility Complex Class II Products of Dendritic Cells (1998) (721)
IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE (1973) (712)
Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature. (1994) (708)
Migration and maturation of Langerhans cells in skin transplants and explants (1990) (688)
Dendritic cells pulsed with protein antigens in vitro can prime antigen- specific, MHC-restricted T cells in situ [published erratum appears in J Exp Med 1990 Oct 1;172(4):1275] (1990) (686)
The CD8+ Dendritic Cell Subset Selectively Endocytoses Dying Cells in Culture and In Vivo (2002) (676)
The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro (1994) (671)
Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells. (1992) (666)
Dendritic cells in the T‐cell areas of lymphoid organs (1997) (619)
The Linkage of Innate to Adaptive Immunity via Maturing Dendritic Cells In Vivo Requires CD40 Ligation in Addition to Antigen Presentation and CD80/86 Costimulation (2004) (616)
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant (2009) (598)
The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies (1990) (596)
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas (2010) (571)
Membrane flow during pinocytosis. A stereologic analysis (1976) (569)
Dendritic Cells: Features and Functions (1980) (566)
The Dendritic Cell Receptor for Endocytosis, Dec-205, Can Recycle and Enhance Antigen Presentation via Major Histocompatibility Complex Class II–Positive Lysosomal Compartments (2000) (551)
Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1 (1994) (546)
Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells (1989) (545)
Transport of peptide-MHC class II complexes in developing dendritic cells. (2000) (534)
Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo (1993) (534)
Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells (1987) (522)
Immune Tolerance After Delivery of Dying Cells to Dendritic Cells In Situ (2002) (504)
Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro (1979) (500)
Identification of proliferating dendritic cell precursors in mouse blood (1992) (488)
Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells. (1999) (485)
Prolonged IFN-γ–producing NKT response induced with α-galactosylceramide–loaded DCs (2002) (475)
The TRAF Family of Signal Transducers Mediates NF-κB Activation by the TRANCE Receptor* (1998) (470)
Dendritic Cells as Adjuvants for Immune-mediated Resistance to Tumors (1997) (469)
Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow. (1993) (467)
Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a). (2005) (466)
Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral Tolerance (2003) (464)
Inaugural Article : avoiding horror autotoxicus. The importance of dendritic cells in peripheral T cell tolerance (2002) (458)
The Formation of Immunogenic Major Histocompatibility Complex Class II–Peptide Ligands in Lysosomal Compartments of Dendritic Cells Is Regulated by Inflammatory Stimuli (2000) (444)
Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients (2005) (442)
Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity (2005) (441)
Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium (1993) (431)
CD8+CD205+ Splenic Dendritic Cells Are Specialized to Induce Foxp3+ Regulatory T Cells1 (2008) (428)
The distinct surface of human blood dendritic cells, as observed after an improved isolation method. (1990) (415)
THE INTERACTION OF SOLUBLE HORSERADISH PEROXIDASE WITH MOUSE PERITONEAL MACROPHAGES IN VITRO (1972) (408)
Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion. (1999) (403)
Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humans. (2002) (399)
Dendritic cells: Understanding immunogenicity (2007) (396)
Trance, a Tumor Necrosis Factor Family Member, Enhances the Longevity and Adjuvant Properties of Dendritic Cells in Vivo (2000) (372)
Immature Dendritic Cells Selectively Replicate Macrophagetropic (M-Tropic) Human Immunodeficiency Virus Type 1, while Mature Cells Efficiently Transmit both M- and T-Tropic Virus to T Cells (1998) (370)
Exploiting dendritic cells to improve vaccine efficacy. (2002) (364)
Human Cd4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1 (2000) (362)
TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells. (1999) (356)
Antigen Presentation by Dendritic Cells after Immunization with DNA Encoding a Major Histocompatibility Complex Class II–restricted Viral Epitope (1997) (347)
Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release (1984) (341)
Dendritic cell–expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice (2007) (339)
The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymus. (1989) (339)
High Levels of a Major Histocompatibility Complex II–Self Peptide Complex on Dendritic Cells from the T Cell Areas of Lymph Nodes (1997) (327)
A subset of dendritic cells induces CD4+ T cells to produce IFN-γ by an IL-12–independent but CD70-dependent mechanism in vivo (2007) (325)
Contribution of dendritic cells to stimulation of the murine syngeneic mixed leukocyte reaction (1980) (325)
Some interfaces of dendritic cell biology (2003) (325)
The endocytic activity of dendritic cells (1995) (323)
Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients. (2006) (321)
Active immunization against cancer with dendritic cells: The near future (2001) (320)
Pillars Article: Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J. Exp. Med.1973. 137: 1142-1162. (2007) (317)
Local and systemic effects of intradermal recombinant interferon-gamma in patients with lepromatous leprosy. (1986) (315)
Replication of HIV-1 in Dendritic Cell-Derived Syncytia at the Mucosal Surface of the Adenoid (1996) (313)
Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages. (2007) (303)
Dendritic cells in transplantation--friend or foe? (2001) (299)
The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine (2008) (298)
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation. (2004) (295)
Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells. (1994) (292)
TRANCE, a Tumor Necrosis Factor Family Member Critical for CD40 Ligand–independent T Helper Cell Activation (1999) (291)
PINOCYTOSIS IN FIBROBLASTS (1974) (290)
Dendritic cells: versatile controllers of the immune system (2007) (287)
Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication (1983) (286)
Langerhans cell (eosinophilic) granulomatosis. A clinicopathologic study encompassing 50 years. (1996) (285)
Antigen processing for amateurs and professionals. (1998) (285)
Dendritic cells in vivo: a key target for a new vaccine science. (2008) (282)
Dendritic cells expand antigen‐specific Foxp3+CD25+CD4+ regulatory T cells including suppressors of alloreactivity (2006) (280)
Antigen capture, processing, and presentation by dendritic cells: recent cell biological studies. (1999) (270)
The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vitro. (1992) (270)
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A (2011) (269)
Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors (1996) (268)
Direct activation of CD8+ cytotoxic T lymphocytes by dendritic cells (1987) (268)
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes (2007) (266)
Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses (2006) (265)
Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A (1986) (262)
A monoclonal antibody specific for mouse dendritic cells. (1982) (260)
Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells. (2005) (259)
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans (2011) (259)
Dendritic cells are accessory cells for the development of anti- trinitrophenyl cytotoxic T lymphocytes (1980) (254)
Macrophages Control the Retention and Trafficking of B Lymphocytes in the Splenic Marginal Zone (2003) (254)
Dendritic cell maturation by innate lymphocytes (2005) (252)
A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels. (1998) (252)
Specialized role of migratory dendritic cells in peripheral tolerance induction. (2013) (251)
Rapid infection of oral mucosal-associated lymphoid tissue with simian immunodeficiency virus. (1999) (251)
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25− T cells into islet-protective Foxp3+ regulatory T cells (2007) (251)
Identification of a novel cell type in peripheral lymphoid organs of mice. IV. Identification and distribution in mouse spleen (1975) (250)
Low levels of HIV-1 infection in cutaneous dendritic cells promote extensive viral replication upon binding to memory CD4+ T cells (1995) (247)
Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves (2009) (245)
Intensified and protective CD4+ T cell immunity in mice with anti–dendritic cell HIV gag fusion antibody vaccine (2006) (244)
Dendritic cells and macrophages can mature independently from a human bone marrow-derived, post-colony-forming unit intermediate. (1996) (241)
Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs. (2002) (240)
Identification of macrophages and dendritic cells in the osteopetrotic (op/op) mouse. (1993) (240)
Recombinant adenovirus is an efficient and non‐perturbing genetic vector for human dendritic cells (1999) (240)
A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals. (1999) (236)
Myeloid dendritic cells (1999) (235)
Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. I. Expression on dendritic cells and other subsets of mouse leukocytes. (1995) (235)
Dendritic cells and the control of immunity: enhancing the efficiency of antigen presentation. (2001) (228)
Lymphokine enhances the expression and synthesis of Ia antigens on cultured mouse peritoneal macrophages (1980) (226)
Immunologic properties of purified epidermal Langerhans cells. Distinct requirements for stimulation of unprimed and sensitized T lymphocytes (1986) (225)
Dendritic cells stimulate primary human cytolytic lymphocyte responses in the absence of CD4+ helper T cells (1990) (223)
The interaction of HIV with dendritic cells: outcomes and pathways (2007) (223)
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide of Streptococcus pneumoniae in the marginal zone of mouse spleen (2003) (222)
Sequestration from immune CD4+ T cells of mycobacteria growing in human macrophages. (1993) (221)
Dendritic Cell-Specific Intercellular Adhesion Molecule 3-Grabbing Nonintegrin/CD209 Is Abundant on Macrophages in the Normal Human Lymph Node and Is Not Required for Dendritic Cell Stimulation of the Mixed Leukocyte Reaction1 (2005) (219)
Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody. (1984) (219)
The use of dendritic cells in cancer immunotherapy. (2003) (219)
Mature dendritic cells boost functionally superior CD8(+) T-cell in humans without foreign helper epitopes. (2000) (218)
Features of the dendritic cell lineage (2010) (218)
Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain (1990) (217)
Dendritic cells are specialized accessory cells along with TGF- for the differentiation of Foxp3+ CD4+ regulatory T cells from peripheral Foxp3 precursors. (2007) (216)
Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction. (2006) (215)
Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGN. (2001) (212)
Accessory cell-T lymphocyte interactions. Antigen-dependent and - independent clustering (1986) (206)
Dendritic cells are the principal cells in mouse spleen bearing immunogenic fragments of foreign proteins (1990) (204)
The Unenlarged Lymph Nodes of HIV-1–infected, Asymptomatic Patients with High CD4 T Cell Counts Are Sites for Virus Replication and CD4 T Cell Proliferation. The Impact of Highly Active Antiretroviral Therapy (1998) (203)
DC-SIGN A Guide to Some Mysteries of Dendritic Cells (2000) (202)
CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain (2008) (200)
Dendritic Cells Charged with Apoptotic Tumor Cells Induce Long-Lived Protective CD4+ and CD8+ T Cell Immunity against B16 Melanoma 1 (2003) (197)
Interleukin 1 enhances T-dependent immune responses by amplifying the function of dendritic cells (1987) (196)
Flt3 signaling-dependent dendritic cells protect against atherosclerosis. (2011) (195)
An electron microscopic study of ciliogenesis in developing epidermis and trachea in the embryo of Xenopus laevis. (1968) (192)
Synthetic Double-Stranded RNAs Are Adjuvants for the Induction of T Helper 1 and Humoral Immune Responses to Human Papillomavirus in Rhesus Macaques (2009) (192)
Dendritic cells are critical accessory cells for thymus-dependent antibody responses in mouse and in man. (1983) (192)
Protein-specific helper T-lymphocyte formation initiated by dendritic cells. (1985) (190)
Isolation of Dendritic Cells (1998) (188)
Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis (1983) (188)
Specific antimononuclear phagocyte monoclonal antibodies. Application to the purification of dendritic cells and the tissue localization of macrophages (1983) (186)
Influenza Virus–induced Dendritic Cell Maturation Is Associated with the Induction of Strong T Cell Immunity to a Coadministered, Normally Nonimmunogenic Protein (2003) (185)
The control of immunity and tolerance by dendritic cell. (2003) (183)
SIGN-R1, a novel C-type lectin expressed by marginal zone macrophages in spleen, mediates uptake of the polysaccharide dextran. (2003) (181)
The anatomy of peripheral lymphoid organs with emphasis on accessory cells: light-microscopic immunocytochemical studies of mouse spleen, lymph node, and Peyer's patch. (1984) (180)
The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells. (2008) (180)
Antibody to Langerin/CD207 localizes large numbers of CD8α+ dendritic cells to the marginal zone of mouse spleen (2009) (179)
The Cutaneous Infiltrates of Leprosy (1982) (176)
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain (2011) (176)
Clustering of dendritic cells, helper T lymphocytes, and histocompatible B cells during primary antibody responses in vitro (1984) (175)
The interaction of immunodeficiency viruses with dendritic cells. (2003) (174)
Cutting Edge: Langerin/CD207 Receptor on Dendritic Cells Mediates Efficient Antigen Presentation on MHC I and II Products In Vivo1 (2008) (168)
Cross-presentation of glycolipid from tumor cells loaded with α-galactosylceramide leads to potent and long-lived T cell–mediated immunity via dendritic cells (2007) (166)
Dendritic cell‐targeted protein vaccines: a novel approach to induce T‐cell immunity (2012) (164)
Direct Type I IFN but Not MDA5/TLR3 Activation of Dendritic Cells Is Required for Maturation and Metabolic Shift to Glycolysis after Poly IC Stimulation (2014) (164)
Functional comparison of the mouse DC-SIGN, SIGNR1, SIGNR3 and Langerin, C-type lectins. (2004) (163)
Stimulation of lymphokine release from T lymphoblasts. Requirement for mRNA synthesis and inhibition by cyclosporin A (1984) (162)
Control of the immune response at the level of antigen-presenting cells: a comparison of the function of dendritic cells and B lymphocytes. (1989) (162)
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q (2006) (160)
Innate Vα14+ natural killer T cells mature dendritic cells, leading to strong adaptive immunity (2007) (160)
Small amounts of superantigen, when presented on dendritic cells, are sufficient to initiate T cell responses (1993) (158)
Glycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice (2006) (152)
High and low affinity carbohydrate ligands revealed for murine SIGN-R1 by carbohydrate array and cell binding approaches, and differing specificities for SIGN-R3 and langerin. (2004) (152)
Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates (1985) (151)
The membrane proteins of the vacuolar system. II. Bidirectional flow between secondary lysosomes and plasma membrane (1980) (149)
Mechanisms of mouse spleen dendritic cell function in the generation of influenza-specific, cytolytic T lymphocytes (1992) (146)
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice (2008) (146)
Accessory cell requirements for the mixed-leukocyte reaction and polyclonal mitogens, as studied with a new technique for enriching blood dendritic cells. (1988) (142)
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates (2011) (142)
Immunotherapy: Bewitched, Bothered, and Bewildered No More (2004) (138)
Maturation and migration of cutaneous dendritic cells. (1995) (138)
The interactions of dendritic cells with antigen-specific, regulatory T cells that suppress autoimmunity. (2006) (138)
Virus replication begins in dendritic cells during the transmission of HIV-1 from mature dendritic cells to T cells (1999) (138)
Anatomy of germinal centers in mouse spleen, with special reference to "follicular dendritic cells" (1978) (137)
Dendritic cells in the immune response: characteristics and recommended nomenclature (A report from the Reticuloendothelial Society Committee on Nomenclature). (1982) (136)
A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells. (2000) (135)
Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates. (2010) (135)
Lipopolysaccharide or Whole Bacteria Block the Conversion of Inflammatory Monocytes into Dendritic Cells In Vivo (2003) (134)
Dendritic cells and the replication of HIV‐1 (1996) (133)
Dendritic Cell Numbers in the Blood of HIV-1 Infected Patients Before and After Changes in Antiretroviral Therapy (2004) (133)
EBNA1-specific CD4+ T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function. (2001) (132)
During HIV‐1 infection most blood dendritic cells are not productively infected and can induce allogeneic CD4+ T cells clonal expansion (1992) (131)
Generation or large numbers of immature and mature dendritic cells from rat bone marrow cultures (1998) (130)
Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program (2007) (130)
Dendritic Cells Cross-Present Latency Gene Products from Epstein-Barr Virus–Transformed B Cells and Expand Tumor-Reactive Cd8+ Killer T Cells (2001) (130)
Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. II. Expression in situ in lymphoid and nonlymphoid tissues. (1995) (129)
APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection (2006) (128)
Accessory cells in murine Peyer's patch. I. Identification and enrichment of a functional dendritic cell (1983) (128)
Identification of immunostimulatory dendritic cells in the synovial effusions of patients with rheumatoid arthritis. (1985) (127)
Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti-human DEC205 monoclonal antibody. (2010) (127)
The effect of immunosuppressive agents on the induction of nuclear factors that bind to sites on the interleukin 2 promoter (1990) (127)
Presentation of a viral T cell epitope expressed in the CDR3 region of a self immunoglobulin molecule. (1993) (127)
The Thy-1-bearing cell of murine epidermis. A distinctive leukocyte perhaps related to natural killer cells (1985) (126)
Dendritic cells: antigen presentation, accessory function and clinical relevance. (1993) (126)
Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed leukocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes (1987) (125)
Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells. (2009) (125)
Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. (2008) (124)
Identification and expression of mouse Langerin (CD207) in dendritic cells. (2002) (122)
CD141+ dendritic cells produce prominent amounts of IFN-α after dsRNA recognition and can be targeted via DEC-205 in humanized mice. (2013) (121)
Dendritic cell development and maturation. (1997) (121)
THE INTERACTION OF PARTICULATE HORSERADISH PEROXIDASE (HRP)-ANTI HRP IMMUNE COMPLEXES WITH MOUSE PERITONEAL MACROPHAGES IN VITRO (1972) (120)
Canarypox Virus-Induced Maturation of Dendritic Cells Is Mediated by Apoptotic Cell Death and Tumor Necrosis Factor Alpha Secretion (2000) (120)
Coexpression of NF-kappa B/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia. (1995) (119)
Unusual phenotype of B cells in the thymus of normal mice (1988) (119)
Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells (2005) (119)
An antigen-independent contact mechanism as an early step in T cell- proliferative responses to dendritic cells (1989) (119)
Selective iodination and polypeptide composition of pinocytic vesicles (1980) (118)
Active replication of HIV-1 at the lymphoepithelial surface of the tonsil. (1997) (117)
Liver macrophages in murine listeriosis. Cell-mediated immunity is correlated with an influx of macrophages capable of generating reactive oxygen intermediates (1985) (116)
Invariant natural killer T cells are preserved in patients with glioma and exhibit antitumor lytic activity following dendritic cell‐mediated expansion (2004) (115)
Use of the fluorescence activated cell sorter to enrich dendritic cells from mouse spleen. (1990) (113)
Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism (1983) (113)
IL-6/IFN-beta 2 in synovial effusions of patients with rheumatoid arthritis and other arthritides. Identification of several isoforms and studies of cellular sources. (1989) (112)
Dendritic cells initiate a two-stage mechanism for T lymphocyte proliferation (1983) (111)
Latent HIV-1 infection in enriched populations of blood monocytes and T cells from seropositive patients. (1991) (111)
DEC-205, a 205-kDa protein abundant on mouse dendritic cells and thymic epithelium that is detected by the monoclonal antibody NLDC-145: purification, characterization, and N-terminal amino acid sequence. (1995) (108)
Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2 (1983) (107)
Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis. (2010) (107)
Targeting of antigens to skin dendritic cells: possibilities to enhance vaccine efficacy (2010) (107)
Mature Dendritic Cells Respond to SDF-1, but not to Several β-Chemokines (1998) (106)
Linking innate to adaptive immunity through dendritic cells. (2008) (105)
Signals arising from antigen-presenting cells. (1991) (105)
Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract (2013) (105)
Quantitation of surface antigens on cultured murine epidermal Langerhans cells: rapid and selective increase in the level of surface MHC products. (1988) (104)
Cell type-dependent retention and transmission of HIV-1 by DC-SIGN. (2003) (104)
Will the Making of Plasmacytoid Dendritic Cells in Vitro Help Unravel Their Mysteries? (2000) (103)
Both dendritic cells and memory T lymphocytes emigrate from organ cultures of human skin and form distinctive dendritic-T-cell conjugates. (1995) (101)
The Hematopoietic Development of Dendritic Cells: A Distinct Pathway for Myeloid Differentiation (1996) (99)
Infection and apoptotic cell death of CD4+ T cells during an immune response to HIV-1-pulsed dendritic cells. (1994) (99)
Specialized antigen-presenting cells. Splenic dendritic cells and peritoneal-exudate cells induced by mycobacteria activate effector T cells that are resistant to suppression (1982) (97)
Distinct features of dendritic cells and anti-Ig activated B cells as stimulators of the primary mixed leukocyte reaction (1989) (97)
The cutaneous infiltrates of leprosy: cellular characteristics and the predominant T-cell phenotypes. (1982) (95)
Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program (2007) (95)
Distribution of horseradish peroxidase (HRP)-anti-HRP immune complexes in mouse spleen with special reference to follicular dendritic cells (1978) (94)
Induction of murine interleukin 1: stimuli and responsive primary cells. (1987) (94)
Neutralizing Monoclonal Antibodies Block Human Immunodeficiency Virus Type 1 Infection of Dendritic Cells and Transmission to T Cells (1998) (93)
Antigen-specific T lymphocytes efficiently cluster with dendritic cells in the human primary mixed-leukocyte reaction. (1988) (90)
Association of SIGNR1 with TLR4-MD-2 enhances signal transduction by recognition of LPS in gram-negative bacteria. (2005) (89)
Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice (2011) (87)
Induction of Epstein-Barr virus-specific cytotoxic T-lymphocyte responses using dendritic cells pulsed with EBNA-3A peptides or UV-inactivated, recombinant EBNA-3A vaccinia virus. (1999) (87)
Classical Flt3L-dependent dendritic cells control immunity to protein vaccine (2014) (86)
Susceptibility of dendritic cells to HIV‐1 infection in vitro (1994) (86)
Calcitonin Gene-Related Peptide Decreases Expression of HLA-DR and CD86 by Human Dendritic Cells and Dampens Dendritic Cell-Driven T Cell-Proliferative Responses Via the Type I Calcitonin Gene-Related Peptide Receptor1 (2000) (85)
The membrane proteins of the vacuolar system I. Analysis of a novel method of intralysosomal iodination (1980) (84)
A comparison of murine epidermal Langerhans cells with spleen dendritic cells. (1985) (84)
Presentation of proteins encapsulated in sterically stabilized liposomes by dendritic cells initiates CD8(+) T-cell responses in vivo. (2000) (82)
Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice (2012) (82)
The function of Ia+ dendritic cells and Ia- dendritic cell precursors in thymocyte mitogenesis to lectin and lectin plus interleukin 1 (1988) (81)
Mature Dendritic Cells Infected with Canarypox Virus Elicit Strong Anti-Human Immunodeficiency Virus CD8+and CD4+ T-Cell Responses from Chronically Infected Individuals (2001) (81)
An analysis of in vitro T cell responsiveness in lepromatous leprosy (1985) (80)
HIV-1 Selectively Infects a Subset of Nonmaturing BDCA1-Positive Dendritic Cells in Human Blood1 (2006) (79)
Dendritic cells and immune-based therapies. (1996) (79)
Two populations of splenic dendritic cells detected with M342, a new monoclonal to an intracellular antigen of interdigitating dendritic cells and some B lymphocytes (1992) (77)
Dendritic Cells Initiate Immune Control of Epstein-Barr Virus Transformation of B Lymphocytes In Vitro (2003) (75)
Intralysosomal accumulation of polyanions. I. Fusion of pinocytic and phagocytic vacuoles with secondary lysosomes (1982) (75)
Endogenously Expressed nef Uncouples Cytokine and Chemokine Production from Membrane Phenotypic Maturation in Dendritic Cells1 (2002) (75)
Macrophages, but not dendritic cells, accumulate colloidal carbon following administration in situ. (1993) (72)
Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus. (2004) (71)
The phenotype of dendritic cells and macrophages. (1983) (70)
A small number of anti-CD3 molecules on dendritic cells stimulate DNA synthesis in mouse T lymphocytes (1989) (70)
DC-SIGN ( CD 209 ) Mediates Dengue Virus Infection of Human Dendritic Cells (2003) (70)
Single Injection of CD34+ Progenitor-Derived Dendritic Cell Vaccine Can Lead to Induction of T-Cell Immunity in Patients With Stage IV Melanoma (2003) (70)
Network of dendritic cells within the muscular layer of the mouse intestine. (2005) (69)
Dendritic cells generated from blood monocytes of HIV-1 patients are not infected and act as competent antigen presenting cells eliciting potent T-cell responses. (1999) (69)
Dendritic Cell Targeting of Survivin Protein in a Xenogeneic Form Elicits Strong CD4+ T Cell Immunity to Mouse Survivin1 (2006) (69)
A new synthetic TLR4 agonist, GLA, allows dendritic cells targeted with antigen to elicit Th1 T‐cell immunity in vivo (2012) (69)
Expression of a Functional Eotaxin (CC Chemokine Ligand 11) Receptor CCR3 by Human Dendritic Cells1 2 3 (2002) (67)
The innate functions of dendritic cells in peripheral lymphoid tissues. (2005) (66)
Targeting of LcrV virulence protein from Yersinia pestis to dendritic cells protects mice against pneumonic plague (2010) (65)
Intraepidermal lymphocytes in psoriatic lesions are activated GMP‐17(TIA‐1)+CD8+CD3+ CTLs as determined by phenotypic analysis (1998) (64)
EVIDENCE THAT CYCLOSPORINE INHIBITS CELL‐MEDIATED IMMUNITY PRIMARILY AT THE LEVEL OF THE T LYMPHOCYTE RATHER THAN THE ACCESSORY CELL (1988) (64)
Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance (2014) (63)
Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8+ T cells (2010) (62)
Production of monoclonal antibodies that recognize the extracellular domain of mouse langerin/CD207. (2007) (62)
Detection and activation of human Vα24+ natural killer T cells using α-galactosyl ceramide-pulsed dendritic cells☆ (2003) (61)
Dendritic cells of the mouse: identification and characterization. (1980) (61)
Mass spectrometry analysis and quantitation of peptides presented on the MHC II molecules of mouse spleen dendritic cells. (2011) (61)
The Decreased Replicative Capacity of Simian Immunodeficiency Virus SIVmac239Δnef Is Manifest in Cultures of Immature Dendritic Cells and T Cells (2000) (61)
Generation and application of new rat monoclonal antibodies against synthetic FLAG and OLLAS tags for improved immunodetection. (2008) (60)
Clonal expansion of human T lymphocytes initiated by dendritic cells (1989) (59)
Glycolipid alpha-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice. (2006) (57)
The Metabolism and Physiology of the Mononuclear Phagocytes (1974) (57)
Broad T cell immunity to the LcrV virulence protein is induced by targeted delivery to DEC‐205/CD205‐positive mouse dendritic cells (2008) (57)
Influence of delayed immune reactions on human epidermal keratinocytes. (1986) (56)
Presentation of Epstein‐Barr virus latency antigens to CD8+, interferon‐γ‐secreting, T lymphocytes (1999) (55)
DEC‐205/CD205+ dendritic cells are abundant in the white pulp of the human spleen, including the border region between the red and white pulp (2008) (55)
The Human Cancer Antigen Mesothelin Is More Efficiently Presented to the Mouse Immune System when Targeted to the DEC‐205/CD205 Receptor on Dendritic Cells (2009) (55)
Clustering with dendritic cells precedes and is essential for T-cell proliferation in a mitogenesis model. (1988) (54)
A New Triggering Receptor Expressed on Myeloid Cells (Trem) Family Member, Trem-Like 4, Binds to Dead Cells and Is a DNAX Activation Protein 12-Linked Marker for Subsets of Mouse Macrophages and Dendritic Cells1 (2009) (54)
Immunogenicity: Role of dendritic cells (1989) (54)
Stimulation of the primary mixed leukocyte reaction. (1985) (52)
Dendritic cells at a DNA vaccination site express the encoded influenza nucleoprotein and prime MHC class I-restricted cytolytic lymphocytes upon adoptive transfer. (2000) (50)
Epitopes on CD45R [T200] molecules define differentiation antigens on murine B and T lymphocytes. (1988) (50)
Efficient loading of identical viral peptide onto class II molecules by antigenized immunoglobulin and influenza virus (1993) (49)
Cytokines amplify the function of accessory cells. (1988) (49)
Dll4–Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice (2012) (47)
Expression of B7 costimulator molecules on mouse dendritic cells. (1995) (47)
HIV gag protein is efficiently cross‐presented when targeted with an antibody towards the DEC‐205 receptor in Flt3 ligand‐mobilized murine DC (2009) (46)
Dendritic Cells, Infected with Vesicular Stomatitis Virus-Pseudotyped HIV-1, Present Viral Antigens to CD4+ and CD8+ T Cells from HIV-1-Infected Individuals1 (2000) (45)
An IFN-γ-IL-18 Signaling Loop Accelerates Memory CD8+ T Cell Proliferation (2008) (44)
Induction of pulmonary mucosal immune responses with a protein vaccine targeted to the DEC-205/CD205 receptor. (2012) (44)
Mature dendritic cells respond to SDF-1, but not to several beta-chemokines. (1998) (44)
Immunogenicity and efficacy of immunodeficiency virus-like particles pseudotyped with the G protein of vesicular stomatitis virus. (2006) (43)
Newcastle Disease Virus Expressing a Dendritic Cell-Targeted HIV Gag Protein Induces a Potent Gag-Specific Immune Response in Mice (2010) (43)
Paucity of functional T-cell memory to melanoma antigens in healthy donors and melanoma patients. (2000) (42)
Some active areas of DC research and their medical potential (2010) (42)
T Cell Studies in a Peptide-Induced Model of Systemic Lupus Erythematosus (2001) (41)
The passenger leukocyte—A fresh look (1988) (40)
Interleukin 1 production during accessory cell-dependent mitogenesis of T lymphocytes (1989) (40)
Interleukin-1 production by mononuclear cells from rheumatoid synovial effusions. (1988) (40)
CD8+ T cells from most HIV‐1‐infected patients, even when challenged with mature dendritic cells, lack functional recall memory to HIV gag but not other viruses (2005) (39)
Bone marrow-derived chimerism in non-irradiated, cyclosporin-treated rats receiving microvascularized limb transplants: evidence for donor-derived dendritic cells in recipient lymphoid tissues. (1995) (38)
Zanvil Alexander Cohn 1926-1993 (1994) (38)
Properties of memory T lymphocytes isolated from the mixed leukocyte reaction. (1985) (38)
Presentation of SIVgag to monkey T cells using dendritic cells transfected with a recombinant adenovirus (2000) (37)
Presentation of mycobacterial antigens by human dendritic cells: lack of transfer from infected macrophages (1993) (37)
Dendritic cells efficiently immunoselect mycobacterial-reactive T cells in human blood, including clonable antigen-reactive precursors. (1992) (36)
SnapShot: Dendritic Cells (2011) (34)
Targeting of envelope domain III protein of DENV type 2 to DEC-205 receptor elicits neutralizing antibodies in mice. (2013) (34)
Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity (2013) (34)
Properties of isolated red pulp macrophages from mouse spleen (1988) (33)
Donor‐derived chimerism in recipients of organ transplants (1993) (33)
Flt3L-dependence helps define an uncharacterized subset of murine cutaneous dendritic cells (2013) (33)
Atraumatic Oral Spray Immunization with Replication-Deficient Viral Vector Vaccines (2007) (31)
Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells. (2002) (31)
Dendritic cells expand Epstein Barr virus specific CD8+ T cell responses more efficiently than EBV transformed B cells. (2005) (31)
Antigen presentation and related immunological aspects of HIV-1 vaccines. (1998) (30)
Human CD 4 1 T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen EBNA (2000) (30)
Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells. (2013) (30)
CpG oligonucleotides induce strong humoral but only weak CD4+ T cell responses to protein antigens in rhesus macaques in vivo. (2005) (30)
siRNA Knockdown of PD-L1 and PD-L2 in Monocyte-Derived Dendritic Cells only Modestly Improves Proliferative Responses to Gag by CD8+ T Cells from HIV-1-Infected Individuals (2009) (29)
normoglycemia in diabetic NOD mice (2007) (29)
IL‐6 enhances the generation of cytolytic T lymphocytes in the allogeneic mixed leucocyte reaction (1992) (29)
Enhanced T-Cell Responses to Glioma Cells Coated With the Anti-EGF Receptor Antibody and Targeted to Activating FcγRs on Human Dendritic Cells (2008) (28)
Treml4, an Ig Superfamily Member, Mediates Presentation of Several Antigens to T Cells In Vivo, Including Protective Immunity to HER2 Protein (2012) (27)
CD45 epitope mapping of human CD1a+ dendritic cells and peripheral blood dendritic cells. (1991) (27)
Increased Macrophage Infection upon Subcutaneous Inoculation of Rhesus Macaques with Simian Immunodeficiency Virus-Loaded Dendritic Cells or T Cells but Not with Cell-Free Virus (2002) (27)
Isolation of Dendritic Cells (1998) (27)
Dendritic Cells and Vaccines (2008) (26)
Mouse spleen lymphoblasts generated in vitro. Recovery in high yield and purity after floatation in dense bovine plasma albumin solutions (1978) (26)
The Sensitization Phase of T‐Cell‐Mediated Immunity a (1988) (25)
Dendritic cells. (1981) (25)
The cell surface of mouse lymphoid dendritic cells. (1982) (25)
Detection and activation of human Valpha24+ natural killer T cells using alpha-galactosyl ceramide-pulsed dendritic cells. (2003) (24)
Induction of interleukin 1 alpha mRNA during the antigen-dependent interaction of sensitized T lymphoblasts with macrophages (1988) (23)
Interleukin 6 is the principal cytolytic T lymphocyte differentiation factor for thymocytes in human leukocyte conditioned medium. (1989) (23)
Growth factor production and requirements during the proliferative response of human T lymphocytes to anti-CD3 monoclonal antibody. (1989) (23)
The Simian Immunodeficiency Virus Δnef Vaccine, after Application to the Tonsils of Rhesus Macaques, Replicates Primarily within CD4+ T Cells and Elicits a Local Perforin-Positive CD8+ T-Cell Response (2002) (22)
Inhibitory effects of colchicine on ciliogenesis in ectoderm of Xenopus laevis. (1970) (21)
Dendritic cell-T cell conjugates that migrate from normal human skin are an explosive site of infection for HIV-1. (1995) (20)
New monoclonal anti-mouse DC-SIGN antibodies reactive with acetone-fixed cells. (2010) (19)
Contrasting efficacy of presentation by major histocompatibility complex class I and class II products when peptides are administered within a common protein carrier, self immunoglobulin (1993) (19)
A single vaccination with attenuated SIVmac 239 via the tonsillar route confers partial protection against challenge with SIVmac 251 at a distant mucosal site, the rectum. (2007) (19)
Spleen deposition of Cryptococcus neoformans capsular glucuronoxylomannan in rodents occurs in red pulp macrophages and not marginal zone macrophages expressing the C-type lectin SIGN-R1. (2008) (18)
CHAPTER 35 – Dendritic cells during infection with HIV-1 and SIV (2001) (18)
Introduction: Cutaneous Dendritic Cells: Distinctive Antigen-Presenting Cells for Experimental Models and Disease States (1995) (18)
Stimulation of human anti-viral CD8+ cytolytic T lymphocytes by dendritic cells. (1995) (18)
Most CD4+ T cells from human immunodeficiency virus-1 infected patients can undergo prolonged clonal expansion. (1989) (17)
Short Communication: The Immunodeficiency Virus Coreceptor, Bonzo/STRL33/TYMSTR, Is Expressed by Macaque and Human Skin- and Blood-Derived Dendritic Cells (2000) (17)
Phagocytosis and fluid-phase pinocytosis. (1982) (17)
Dendritic cell maturation by innate lymphocytes: Coordinated stimulation of innate and adaptive immunity (2020) (16)
APOBEC 3 G / 3 F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection (2006) (16)
Dendritic cells: from the fabric of immunology. (2004) (16)
THE DENDRITIC CELL AND ITS ROLE IN IMMUNOGENICITY SYSTEM (1991) (16)
PINOCYTOSIS IN FIBROBLASTS Quantitative Studies In Vitro (2003) (16)
Generation of anti-human DEC205/CD205 monoclonal antibodies that recognize epitopes conserved in different mammals. (2012) (15)
Localization and intracellular transport of MHC class II molecules in bone marrow-derived dendritic cells. (1997) (15)
Anti–CTLA‐4 synergizes with dendritic cell–targeted vaccine to promote IL‐3–dependent CD4+ effector T cell infiltration into murine pancreatic tumors (2019) (15)
A triple tribute to the experiment that transformed biology (1994) (15)
The HIV-1 life cycle is blocked at two different points in mature dendritic cells. (1997) (14)
The immunodeficiency virus coreceptor, Bonzo/STRL33/TYMSTR, is expressed by macaque and human skin- and blood-derived dendritic cells. (2000) (14)
Dendritic Cells Induce a Subpopulation of IL-12Rβ2-Expressing Treg that Specifically Consumes IL-12 to Control Th1 Responses (2016) (14)
Dendritic Cells and Macrophages — Current Knowledge of Their Distinctive Properties and Functions (1980) (13)
Erratum: Identification and expression of mouse Langerin (CD207) in dendritic cells (International Immunology (2002) vol. 14 (433-444)) (2002) (13)
The simian immunodeficiency virus deltaNef vaccine, after application to the tonsils of Rhesus macaques, replicates primarily within CD4(+) T cells and elicits a local perforin-positive CD8(+) T-cell response. (2002) (13)
Vaccines to Treat Drug Addiction (2004) (12)
Studies with a monoclonal antibody to mouse dendritic cells. (1983) (12)
Donor Leukocyte Migration Following Extremity Transplantation in an Experimental Model (1992) (12)
Migration of Donor Leukocytes from Limb Allografts into Host Lymphoid Tissues (1990) (12)
High and low af ® nity carbohydrate ligands revealed for murine SIGN-R 1 by carbohydrate array and cell binding approaches , and differing speci ® cities for SIGN-R 3 and langerin (12)
Dendritic cells: clinical aspects. (1989) (12)
Mechanisms of host resistance to infectious agents, tumors, and allografts : a conference in recognition of the Trudeau Institute centennial (1986) (11)
14 – Antigen Presentation by Dendritic Cells (1988) (11)
Dendritic and B-cell function during antibody responses in normal and immunodeficient (xid) mouse spleen cultures. (1987) (11)
The binding of antigen presenting cells to T lymphocytes. (1988) (10)
The dendritic cell in clinical immunology: the AIDS example. (1996) (10)
Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance (2014) (10)
EBNA 1-specific CD 4 + T cells in healthy carriers of Epstein-Barr virus are primarily Th 1 in function (2000) (9)
Identification of a 24-kDa cytokine that is required for development of cytolytic T lymphocytes. (1988) (9)
An approach to isolating T cell lines that react to antigens presented on the surface of dendritic cells (1991) (9)
IMMUNOLOGIC PROPERTIES OF PURIFIED EPIDERMAL LANGERHANS CELLS (2003) (9)
Dendritic cells as immunogens for human CTL responses. (1997) (9)
Membrane Flow During Endocytosis (1980) (9)
A NOVEL ADHERENT CELL IN MOUSE LYMPHOID ORGANS (1975) (9)
Strategy for Identifying Dendritic Cell-Processed CD4+ T Cell Epitopes from the HIV Gag p24 Protein (2012) (9)
ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis (2015) (8)
Research on human subjects in the JEM (2005) (8)
Tolerizing mice to human leukocytes: a step toward the production of monoclonal antibodies specific for human dendritic cells. (1993) (8)
Association of SIGNR 1 with TLR 4 – MD2 enhances signal transduction by recognition of LPS in gram-negative bacteria (2005) (8)
In vivo targeting of protein antigens to dendritic cells using anti‐DEC‐205 single chain antibody improves HIV Gag specific CD4+ T cell responses protecting from airway challenge with recombinant vaccinia‐gag virus (2017) (8)
Calcitonin gene-related peptide decreases expression of HLA-DR and CD86 by human dendritic cells and dampens dendritic cell-driven T cell- proliferative responses via the type I calcitonin gene-related peptide receptor (2020) (7)
Dendritic cells crossprime allo-specific self-restricted CD4(+) T cells after coculture with dead allogeneic cells. (2002) (7)
Induction of neutralising antibodies restricts the use of human granulocyte/macrophage colony stimulating factor for vaccine studies in rhesus macaques. (2004) (7)
Dendritic Cells: Important Adjuvants During DNA Vaccination (2013) (7)
Epitope mapping on the dendritic cell-specific ICAM-3-grabbing non-integrin (DC-SIGN) pathogen-attachment factor. (2010) (7)
Cutaneous dendritic cells promote replication of immunodeficiency viruses. (1997) (7)
The immunological and infectious sequelae of the acquired immune deficiency syndrome (1988) (7)
Antibody responses to T-dependent antigens: contributions of dendritic cells and helper T lymphocytes. (1985) (7)
The dendritic cell advantage: New focus for immune-based therapies. (2000) (7)
THE PRIMARY MIXED LEUKOCYTE REACTION IN MICE (1983) (6)
Insertion of myoglobin T-cell epitopes into the Escherichia coli alkaline phosphatase. (1990) (6)
Bioassays for the detection of a cytokine that enhances the development of cytolytic T lymphocytes. (1987) (6)
Difficulties in obtaining monoclonal antibodies to subsets of human leukocytes, using neonatal tolerance induction in mice. (1995) (6)
Mononuclear phagocytes as targets for cytolytic T lymphocytes. (1987) (6)
Some Scientific and Organizational Challenges in Cancer Immunology (2009) (5)
DENDRITIC CELLS, AN IMPORTANT NEW CELL TYPE IN MHC-LINKED FUNCTIONS (1980) (5)
GM-CSF — A Granulocyte/Macrophage/Dendritic Cell Stimulating Factor1 (1993) (5)
Correction: Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity (2013) (5)
Harnessing the Immune System Against Human Glioma (2005) (4)
Some Biological Features of Dendritic Cells in the Mouse (2007) (4)
Intracellular iodination of lysosome membrane for studies of membrane composition and recycling. (1983) (4)
PE-Cy5.5 conjugates bind to the cells expressing mouse DEC205/CD205. (2012) (4)
Purification and Characterization of Epidermal Langerhans Cells (1987) (4)
: Dendritic cells bring home the Lasker (2007) (4)
The Role and Mechanism of Action of Dendritic Cells in Transplantation Immunity (1986) (4)
Immunogens and Antigen Processing: Report from a Global HIV Vaccine Enterprise Working Group (2010) (3)
Properties of resident and inflammatory macrophages in mouse liver (1985) (3)
Mechanisms of lymphocyte activation and immune regulation X : innate immunity (2005) (3)
Anti-DEC205 Mediated Delivery of Self-Antigen to Dendritic Cell Restores Tolerance in Spontaneous EAU (2012) (3)
HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt 3 ligand-mobilized murine dendritic cells (2011) (3)
The central nervous system in mucosal vaccination of rhesus macaques with simian immunodeficiency virus Deltanef. (2007) (2)
The Homogeneity and Discreteness of Membrane Domains (1985) (2)
Systemic Lupus Erythematosus T Cell Studies in a Peptide-Induced Model of and Betty Diamond (2001) (2)
Nobel Prize to immunology (2011) (2)
The central nervous system in mucosal vaccination of rhesus macaques with simian immunodeficiency virus Δnef (2007) (2)
A simple method to grow large numbers of dendritic cells from human peripheral blood (1994) (2)
In vivo targeting of HIV gag to dendritic cells in combination with poly ICLC is safe and immunogenic in healthy volunteers (2012) (2)
The Janus Face of Macrophages in Immunity (2014) (2)
Production of Interleukin‐6 and a Cytolytic T Lymphocyte Differentiation Factor by Mononuclear Cells (1989) (1)
Immunocytochemical studies of human mononuclear phagocytes and dendritic cells (1985) (1)
Introduction to Some of the Issues and Mysteries Considered in this Book on Dendritic Cells (2008) (1)
Vaccines Based on Dendritic Cell Biology (2016) (1)
Identification and Characterization of Interleukin‐6/Interferon‐β2 in Synovial Effusions of Patients with Rheumatoid Arthritis and Other Arthritides (1989) (1)
OF EXOGENOUS PROTEIN ANTIGENS BY DENDRITIC CELLS TO T CELL CLONES Intact Protein Is Presented Best by Immature , Epidermal Langerhans Cells (2003) (1)
James Gerald Hirsch. (2004) (1)
Dendritic cell subsets (2010) (1)
Ralph Steinman--pioneering new perspectives on the immune system and infectious diseases. Interviewed by Marilynn Larkin. (2003) (1)
Development of Cytolytic T Lymphocytes in Thymus Culture Requires a Cytokine Sharing Homology with IL‐6 a (1989) (1)
Uptake and presentation of phagocytosed antigens by dendritic cells (1999) (1)
Dendritic Cells in Transplantation— Review Friend or Foe? (2001) (1)
Frontline : Broad T cell immunity to the LcrV virulence protein is induced by targeted delivery to DEC-205 / CD 205-positive mouse dendritic cells (2008) (1)
Leukocyte Reaction Dendritic Cell Stimulation of the Mixed for Human Lymph Node and Is Not Required Abundant on Macrophages in the Normal Molecule 3-Grabbing Nonintegrin/CD209 Is Dendritic Cell-Specific Intercellular Adhesion (2005) (1)
Peptide Receptor Via the Type I Calcitonin Gene-Related Cell-Driven T Cell-Proliferative Responses Dendritic Cells and Dampens Dendritic Expression of HLA-DR and CD 86 by Human Calcitonin Gene-Related Peptide Decreases (2000) (0)
Bewildered No More Immunotherapy: Bewitched, Bothered, and (2008) (0)
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The distinct surface of human blood dendritic cells as observed following an improved isolation method (2020) (0)
Dendritic cells: function 1 (WS-024a) Chairpersons: Atsushi Kumanogoh, Paola Castagnoli (2010) (0)
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It's Those Snacks [196-?] (1960) (0)
by dendritic cells initiates CD8+ T-cell responses in vivo Presentation of proteins encapsulated in sterically stabilized liposomes (2013) (0)
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Virus to T Cells Cells Efficiently Transmit both Mand T-Tropic Immunodeficiency Virus Type 1 , while Mature Macrophagetropic ( M-Tropic ) Human Immature Dendritic Cells Selectively Replicate (1998) (0)
THE REGULATION OF TRANCE EXPRESSION ON T CELLS IN VITRO AND IN VIVO DURING ACUTE HEART ALLOGRAFT REJECTION AND ALLOGRAFT TOLERANCE (1999) (0)
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Human Dendritic Cells Chemokine Ligand 11) Receptor CCR3 by Expression of a Functional Eotaxin (CC (2002) (0)
Immunity to HER 2 Protein T Cells In Vivo , Including Protective Mediates Presentation of Several Antigens to Treml 4 , an Ig Superfamily Member (2011) (0)
Cell Immunity to Mouse Survivin in a Xenogeneic Form Elicits Strong CD4+ T Dendritic Cell Targeting of Survivin Protein (2013) (0)
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Small amounts of superantigen on dendritic cells are sufficient to initiate T cell responses (2020) (0)
Nonmaturing BDCA 1-Positive Dendritic HIV-1 Selectively Infects a Subset of (2005) (0)
7th International Workshop on Langerhans Cells (2010) (0)
Dendritic cells: linking innate to different forms of adaptive immunity (2009) (0)
The Tissue Distribution o f the B7-2 Cost imulator in Mice: Abundant Express ion on Dendri t ic Cells In Situ and D u r i n g Maturat ion In Vitro (2003) (0)
INABA AND STEINMAN 249 methyl mannoside (2003) (0)
Initiating protective T cell immunity by targeting antigens directly to maturing dendritic cells in lymphoid tissues (2005) (0)
Dendritic cell-initiated T lymphocyte activation (1985) (0)
Proliferating Dendritic Cell Progenitors in H u m a n Blood (2003) (0)
Cancer vaccines :sixth international symposium (2009) (0)
Newcastle Disease Virus Expressing a Dendritic Cell-Targeted HIV Gag Protein Induces a Potent Gag-Speciﬁc Immune Response in Mice (cid:1) (2011) (0)
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Regulatory T + Specialized to Induce Foxp3 Splenic Dendritic Cells Are + CD205+ CD8 (2008) (0)
The Simian Immunodeﬁciency Virus (cid:2) nef Vaccine, after Application to the Tonsils of Rhesus Macaques, Replicates Primarily within CD4 (cid:1) T Cells and Elicits a Local Perforin-Positive CD8 (cid:1) T-Cell Response (2001) (0)
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Comprar Annals of the New York Academy of Sciences, Volume 1062, Human Immunology: Patient-Based Research | Ralph M. Steinman | 9781573316071 | Wiley (2008) (0)
Dr. Zanvil A. Cohn (1926-1993) (1993) (0)
Dendritic Cells in Fundamental and Clinical Immunology: Life in Venice (1998) (0)
cells and CD163 + FXIIIA + macrophages (2007) (0)
The JEM and the JCB (2004) (0)
The JEM and the JCB (2004) (0)
The initiation of cell-mediated immune responses (1992) (0)
Method and composition for the production of mature dendritic cells (1998) (0)
Mixed leukocyte reaction in mice. (1983) (0)
Molecular analysis of microenvironment (1993) (0)
Introduction: Keystone Symposium on Macrophage Biology (1999) (0)
Vaccines that target dendritic cells (ML10) Chairperson: Kayo Inaba (2010) (0)
Dendritic Cells Membrane Phenotypic Maturation in Cytokine and Chemokine Production from Uncouples nef Endogenously Expressed (2002) (0)
PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version (2005) (0)
DENDRITIC CELLS PLUS TGF-BETA1 DIFFERENTIATED NAÏVE CD4+ T CELLS BUT NOT NATURAL REGULATORY T CELLS PROTECT ALLOGRAFTS: 510 (2008) (0)
The Nobel Prizes of 2011 Dendritic cells ( DC ) and their Toll-like receptors ( TLR ) : Vital elements at the core of all individual immune responses (2012) (0)
A molecular strategy to identify molecules that are specific for dendritic cells and/or critical to their unique immunostimulatory function. (1995) (0)
Foreword (2005) (0)
Dendritic cells mobilize NKT lymphocytes as adjuncts and adjuvants for anti-tumor immunity (2006) (0)
Dendritic cells arecritical accessory cells forthymus-dependent antibody responses inmouseandinman (1983) (0)
Ralph Steinman Speaks about Dendritic Cells and Immune-Based Vaccines (2011) (0)
Pillars Article: Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking. Science. 1998. 282: 480-483. (2017) (0)
Book Review:The Macrophage. Volume 2 of Biological Structure and Function. B. Vernon-Roberts (1974) (0)
Subcutaneous immunization to HIV gag is potentiated by Flt3L and develops through classical rather than migratory dendritic cells (2013) (0)
Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients (2007) (0)
Symposium on surface molecules in leukocyte interactions (1988) (0)
Ralph Steinman: Dendritic cells bring home the Lasker (2007) (0)

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