Randy Schekman
#1,768
Most Influential Person Now
Nobel prize winning American cell biologist
Randy Schekman's AcademicInfluence.com Rankings
Randy Schekmanbiology Degrees
Biology
#49
World Rank
#92
Historical Rank
#30
USA Rank
Cell Biology
#4
World Rank
#4
Historical Rank
#1
USA Rank
Molecular Biology
#27
World Rank
#27
Historical Rank
#18
USA Rank
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Biology
Randy Schekman's Degrees
- PhD Cell Biology Stanford University
Why Is Randy Schekman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Randy Wayne Schekman is an American cell biologist at the University of California, Berkeley, former editor-in-chief of Proceedings of the National Academy of Sciences and former editor of Annual Review of Cell and Developmental Biology. In 2011, he was announced as the editor of eLife, a new high-profile open-access journal published by the Howard Hughes Medical Institute, the Max Planck Society and the Wellcome Trust launching in 2012. He was elected to the National Academy of Sciences in 1992. Schekman shared the 2013 Nobel Prize for Physiology or Medicine with James Rothman and Thomas C. Südhof for their ground-breaking work on cell membrane vesicle trafficking.
Randy Schekman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway (1980) (1728)
- A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides (1988) (1370)
- COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum (1994) (1310)
- Coat Proteins and Vesicle Budding (1996) (967)
- Bi-directional protein transport between the ER and Golgi. (2004) (887)
- Order of events in the yeast secretory pathway (1981) (753)
- Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway (1990) (694)
- COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes (1998) (628)
- Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole (1982) (543)
- Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae (1979) (509)
- Multiple Cargo Binding Sites on the COPII Subunit Sec24p Ensure Capture of Diverse Membrane Proteins into Transport Vesicles (2003) (495)
- Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle (2005) (481)
- SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER (1993) (468)
- Vesicle-mediated protein sorting. (1992) (447)
- Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation (1997) (434)
- Protein Translocation Across Biological Membranes (2005) (427)
- Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction (2016) (420)
- COPII–cargo interactions direct protein sorting into ER-derived transport vesicles (1998) (412)
- A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum (1987) (400)
- Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes (1995) (387)
- Requirement for a GTPase-activating protein in vesicle budding from the endoplasmic reticulum. (1993) (376)
- Sec61p and BiP directly facilitate polypeptide translocation into the ER (1992) (356)
- The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis (2013) (353)
- Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum. (1992) (352)
- Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex (1991) (349)
- Glycosylation and processing of prepro-α-factor through the yeast secretory pathway (1984) (335)
- Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast (1989) (315)
- TANGO1 Facilitates Cargo Loading at Endoplasmic Reticulum Exit Sites (2009) (314)
- Reconstitution of SEC gene product-dependent intercompartmental protein transport (1988) (311)
- Dynamics of the COPII coat with GTP and stable analogues (2001) (304)
- COPII and the regulation of protein sorting in mammals (2011) (293)
- A Primer on Vesicle Budding (1999) (291)
- Ubiquitin-dependent regulation of COPII coat size and function (2012) (286)
- A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome (1993) (285)
- Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal endoplasmic-reticulum-to-Golgi trafficking (2006) (276)
- Cargo selection into COPII vesicles is driven by the Sec24p subunit (2002) (276)
- Lyticase: Endoglucanase and Protease Activities That Act Together in Yeast Cell Lysis (1980) (274)
- COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast (1995) (269)
- Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast (1981) (264)
- BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum. (1995) (255)
- A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast (1988) (255)
- Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion (2015) (249)
- Annual review of cell and developmental biology. (2007) (248)
- Differential trafficking and timed localization of two chitin synthase proteins, Chs2p and Chs3p [published erratum appears in J Cell Biol 1996 Dec;135(6 Pt 2):1925] (1996) (247)
- Protein localization and membrane traffic in yeast. (1985) (242)
- Functional compartments of the yeast Golgi apparatus are defined by the sec7 mutation. (1989) (241)
- Localization of components involved in protein transport and processing through the yeast Golgi apparatus (1991) (241)
- The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins. (1993) (236)
- Topology and functional domains of Sec63p, an endoplasmic reticulum membrane protein required for secretory protein translocation (1992) (232)
- UNC93B1 mediates differential trafficking of endosomal TLRs (2013) (228)
- The yeast clathrin adaptor protein complex 1 is required for the efficient retention of a subset of late Golgi membrane proteins. (2002) (224)
- ER export: public transportation by the COPII coach. (2001) (220)
- Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREs. (1998) (214)
- Gene dosage-dependent secretion of yeast vacuolar carboxypeptidase Y (1986) (210)
- Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure (2009) (205)
- In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles (2009) (203)
- COPII-mediated vesicle formation at a glance (2011) (201)
- Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes. (1998) (201)
- Broad role for YBX1 in defining the small noncoding RNA composition of exosomes (2017) (201)
- A possible role for RNA polymerase in the initiation of M13 DNA synthesis. (1971) (198)
- Mammalian Sec23p homologue is restricted to the endoplasmic reticulum transitional cytoplasm. (1991) (196)
- Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi network (2012) (196)
- Transparency in authors’ contributions and responsibilities to promote integrity in scientific publication (2017) (192)
- SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer (1992) (187)
- Protein sorting at the trans-Golgi network. (2014) (185)
- RNA synthesis initiates in vitro conversion of M13 DNA to its replicative form. (1972) (184)
- The genetic basis of a craniofacial disease provides insight into COPII coat assembly. (2007) (183)
- A test of clathrin function in protein secretion and cell growth. (1985) (179)
- Regulated import and degradation of a cytosolic protein in the yeast vacuole (1991) (179)
- Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70 (1993) (175)
- SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum (1989) (175)
- Purification and characterization of SAR1p, a small GTP-binding protein required for transport vesicle formation from the endoplasmic reticulum. (1993) (175)
- Localized secretion of acid phosphatase reflects the pattern of cell surface growth in saccharomyces cerevisiae (1980) (175)
- The yeasts Rho1p and Pkc1p regulate the transport of chitin synthase III (Chs3p) from internal stores to the plasma membrane (2003) (172)
- Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles. (1991) (170)
- Chs1p and Chs3p, two proteins involved in chitin synthesis, populate a compartment of the Saccharomyces cerevisiae endocytic pathway. (1996) (170)
- GTP/GDP exchange by Sec12p enables COPII vesicle bud formation on synthetic liposomes (2004) (169)
- Multienzyme Systems of DNA Replication (1974) (168)
- Binding of Secretory Precursor Polypeptides to a Translocon Subcomplex Is Regulated by BiP (1997) (168)
- Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment (2014) (163)
- SEC11 is required for signal peptide processing and yeast cell growth (1988) (160)
- GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction. (1990) (160)
- A subset of yeast vacuolar protein sorting mutants is blocked in one branch of the exocytic pathway (2002) (156)
- The Lumenal Domain of Sec63p Stimulates the ATPase Activity of BiP and Mediates BiP Recruitment to the Translocon in Saccharomyces cerevisiae (1997) (155)
- Chs6p-dependent anterograde transport of Chs3p from the chitosome to the plasma membrane in Saccharomyces cerevisiae. (1998) (155)
- Lst1p and Sec24p Cooperate in Sorting of the Plasma Membrane Atpase into Copii Vesicles in Saccharomyces cerevisiae (2000) (148)
- New mutants of Saccharomyces cerevisiae affected in the transport of proteins from the endoplasmic reticulum to the Golgi complex. (1996) (147)
- Myosin V transports secretory vesicles via a Rab GTPase cascade and interaction with the exocyst complex. (2011) (147)
- Sec31 encodes an essential component of the COPII coat required for transport vesicle budding from the endoplasmic reticulum. (1997) (146)
- Structure of the Sec23p/24p and Sec13p/31p complexes of COPII (2001) (145)
- SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus. (1988) (144)
- Clathrin: a role in the intracellular retention of a Golgi membrane protein. (1989) (144)
- Endoplasmic Reticulum Stress-Activated Transcription Factor ATF6α Requires the Disulfide Isomerase PDIA5 To Modulate Chemoresistance (2014) (144)
- Out of the ER--outfitters, escorts and guides. (1999) (144)
- Protein transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast (1988) (143)
- Sec16p potentiates the action of COPII proteins to bud transport vesicles (2002) (142)
- Unconventional Secretion, Unconventional Solutions (2013) (141)
- A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum (2010) (140)
- The yeast SEC17 gene product is functionally equivalent to mammalian alpha-SNAP protein. (1992) (140)
- COPII and secretory cargo capture into transport vesicles. (1997) (140)
- Ceramide Biosynthesis Is Required for the Formation of the Oligomeric H+-ATPase Pma1p in the Yeast Endoplasmic Reticulum* (2002) (139)
- The yeast SEC53 gene encodes phosphomannomutase. (1988) (139)
- Genetic and biochemical analysis of vesicular traffic in yeast (1992) (138)
- Climate change and the integrity of science. (2010) (137)
- Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles (1991) (137)
- GPI anchor attachment is required for Gas1p transport from the endoplasmic reticulum in COP II vesicles. (1996) (137)
- Concentrative sorting of secretory cargo proteins into COPII-coated vesicles (2002) (136)
- Sec12p-dependent membrane binding of the small GTP-binding protein Sar1p promotes formation of transport vesicles from the ER (1991) (136)
- Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro (1993) (134)
- Coordination of COPII vesicle trafficking by Sec23. (2008) (134)
- The engagement of Sec61p in the ER dislocation process. (1999) (134)
- Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme (1985) (133)
- Exomer: a coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast (2006) (132)
- An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast. (1983) (130)
- Reconstitution of Retrograde Transport from the Golgi to the ER In Vitro (1998) (128)
- COPII - a flexible vesicle formation system. (2013) (127)
- The role of stress proteins in membrane biogenesis. (1988) (127)
- Yeast beta- and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic. (1994) (127)
- Nuclear congression and membrane fusion: two distinct events in the yeast karyogamy pathway (1994) (123)
- Mechanism of Polypeptide Translocation into the Endoplasmic Reticulum* (1996) (123)
- Initiation of DNA synthesis: synthesis of phiX174 replicative form requires RNA synthesis resistant to rifampicin. (1972) (122)
- Structural and functional dissection of Sec62p, a membrane-bound component of the yeast endoplasmic reticulum protein import machinery (1990) (121)
- The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae. (2000) (121)
- Sec23p and a novel 105-kDa protein function as a multimeric complex to promote vesicle budding and protein transport from the endoplasmic reticulum. (1992) (119)
- Export of major cell surface proteins is blocked in yeast secretory mutants (1983) (119)
- Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes (2019) (119)
- Remodeling of ER‐exit sites initiates a membrane supply pathway for autophagosome biogenesis (2017) (118)
- Cloning and functional characterization of mammalian homologues of the COPII component Sec23. (1996) (118)
- Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro (1996) (118)
- GAL2 codes for a membrane-bound subunit of the galactose permease in Saccharomyces cerevisiae (1986) (117)
- Characteristics of endoplasmic reticulum-derived transport vesicles (1994) (117)
- Surface structure of the COPII-coated vesicle (2001) (116)
- Structure, assembly, and secretion of octameric invertase. (1987) (115)
- Lasker Basic Medical Research Award (2002) (115)
- Yeast secretory mutants that block the formation of active cell surface enzymes (1984) (115)
- The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function. (2007) (114)
- Localized deposition of chitin on the yeast cell surface in response to mating pheromone. (1979) (113)
- The karyogamy gene KAR2 and novel proteins are required for ER-membrane fusion (1994) (112)
- Interaction between BiP and Sec63p is required for the completion of protein translocation into the ER of Saccharomyces cerevisiae (1995) (111)
- Selective Uptake of Cytosolic, Peroxisomal, and Plasma Membrane Proteins into the Yeast Lysosome for Degradation (*) (1996) (110)
- The Secretory Process and Yeast Cell-surface Assembly (1982) (110)
- Yeast Sec23p acts in the cytoplasm to promote protein transport from the endoplasmic reticulum to the Golgi complex in vivo and in vitro. (1989) (109)
- COPII-coated vesicles: flexible enough for large cargo? (2005) (108)
- How journals like Nature, Cell and Science are damaging science (2013) (108)
- SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion (2013) (107)
- Protein Translocation How Hsp70 Pulls It Off (1999) (104)
- Self-correction in science at work (2015) (104)
- The structure of the COPII transport-vesicle coat assembled on membranes (2013) (104)
- Analysis of polypeptide transit through yeast secretory pathway. (1991) (99)
- Sec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex (1994) (99)
- Uncoupled Packaging of Amyloid Precursor Protein and Presenilin 1 into Coat Protein Complex II Vesicles* (2005) (97)
- Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat (2012) (95)
- Peroxisomes are juxtaposed to strategic sites on mitochondria. (2014) (94)
- Ten proteins required for conversion of phiX174 single-stranded DNA to duplex form in vitro. Resolution and reconstitution. (1975) (93)
- Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor (2016) (91)
- Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins (2008) (91)
- Reconstitution of transport from endoplasmic reticulum to Golgi complex using endoplasmic reticulum-enriched membrane fraction from yeast. (1992) (90)
- Clustering and endocytosis of membrane receptors can be induced in mature erythrocytes of neonatal but not adult humans. (1976) (89)
- Structural and functional characterization of Sec66p, a new subunit of the polypeptide translocation apparatus in the yeast endoplasmic reticulum. (1993) (88)
- Traffic COPs and the formation of vesicle coats. (1996) (88)
- Early steps in processing of yeast glycoproteins. (1984) (88)
- Sec24p and Iss1p function interchangeably in transport vesicle formation from the endoplasmic reticulum in Saccharomyces cerevisiae. (2000) (86)
- Biochemical requirements for the targeting and fusion of ER-derived transport vesicles with purified yeast Golgi membranes (1996) (85)
- Interaction of Sla2p's ANTH domain with PtdIns(4,5)P2 is important for actin-dependent endocytic internalization. (2004) (85)
- Pho86p, an endoplasmic reticulum (ER) resident protein in Saccharomyces cerevisiae, is required for ER exit of the high-affinity phosphate transporter Pho84p. (2000) (84)
- Coat assembly directs v-SNARE concentration into synthetic COPII vesicles. (1998) (83)
- Multibudded tubules formed by COPII on artificial liposomes (2011) (83)
- Selective packaging of cargo molecules into endoplasmic reticulum-derived COPII vesicles. (1997) (83)
- Role of Vma21p in assembly and transport of the yeast vacuolar ATPase. (2004) (83)
- Does COPI Go Both Ways? (1997) (82)
- The secretory pathway in yeast (1982) (82)
- Avoidance of Autophagy Mediated by PlcA or ActA Is Required for Listeria monocytogenes Growth in Macrophages (2015) (81)
- Polypeptide translocation across the endoplasmic reticulum membrane. (1992) (81)
- Sec61p serves multiple roles in secretory precursor binding and translocation into the endoplasmic reticulum membrane. (1998) (80)
- COPII-coated membranes function as transport carriers of intracellular procollagen I (2017) (78)
- The role of coat proteins in the biosynthesis of secretory proteins. (1995) (76)
- Genetic and biochemical characterization of clathrin-deficient Saccharomyces cerevisiae (1987) (75)
- Chs5/6 complex: a multiprotein complex that interacts with and conveys chitin synthase III from the trans-Golgi network to the cell surface. (2006) (75)
- The ADP ribosylation factor-nucleotide exchange factors Gea1p and Gea2p have overlapping, but not redundant functions in retrograde transport from the Golgi to the endoplasmic reticulum. (2001) (75)
- A new form of DNA polymerase 3 and a copolymerase replicate a long, single-stranded primer-template. (1973) (75)
- Yeast clathrin has a distinctive light chain that is important for cell growth (1990) (74)
- A hitchhiker's guide to analysis of the secretory pathway in yeast. (1989) (73)
- Biogenesis of γ-secretase early in the secretory pathway (2007) (72)
- Structural and functional dissection of a membrane glycoprotein required for vesicle budding from the endoplasmic reticulum (1991) (72)
- Genes required for completion of import of proteins into the endoplasmic reticulum in yeast (1984) (71)
- The mechanism of replication of phi X174 single-stranded DNA. 3. An enzymic study of the structure of the replicative form II DNA. (1971) (71)
- A novel GTP-binding protein–adaptor protein complex responsible for export of Vangl2 from the trans Golgi network (2013) (70)
- SSS1 encodes a stabilizing component of the Sec61 subcomplex of the yeast protein translocation apparatus. (1994) (70)
- ϵ‐COP is a structural component of coatomer that functions to stabilize α‐COP (1998) (68)
- Invertase beta-galactosidase hybrid proteins fail to be transported from the endoplasmic reticulum in Saccharomyces cerevisiae (1984) (67)
- Product of SEC53 is required for folding and glycosylation of secretory proteins in the lumen of the yeast endoplasmic reticulum. (1987) (66)
- Replication of bacteriophage M13. I. Sedimentation analysis of crude lysates of M13-infected bacteria. (1969) (66)
- Expression of concern. (2008) (65)
- Domains of receptor mobility and endocytosis in the membranes of neonatal human erythrocytes in the membranes of neonatal human erythrocytes and reticulocytes are deficient in spectrin (1979) (63)
- The protein-vesicle network of autophagy. (2014) (63)
- Vps10p transport from the trans-Golgi network to the endosome is mediated by clathrin-coated vesicles. (2001) (61)
- Secretory vesicles externalize the major plasma membrane ATPase in yeast (1988) (61)
- Actin from Saccharomyces cerevisiae (1982) (61)
- 23 Genes, 23 years later (2004) (61)
- The role of the endoplasmic reticulum in peroxisome biogenesis. (2013) (60)
- Genetic and biochemical evaluation of eucaryotic membrane protein topology: multiple transmembrane domains of Saccharomyces cerevisiae 3-hydroxy-3-methylglutaryl coenzyme A reductase (1990) (60)
- Unique COPII component AtSar1a/AtSec23a pair is required for the distinct function of protein ER export in Arabidopsis thaliana (2015) (59)
- Glycosylation and processing of prepro-alpha-factor through the yeast secretory pathway. (1984) (59)
- Self‐assembly of minimal COPII cages (2003) (59)
- The exomer coat complex transports Fus1p to the plasma membrane via a novel plasma membrane sorting signal in yeast. (2009) (59)
- Peroxisomes: Another Branch of the Secretory Pathway? (2005) (59)
- Characterization of a gene product (Sec53p) required for protein assembly in the yeast endoplasmic reticulum (1985) (58)
- SEC mutants and the secretory apparatus (2002) (57)
- "BFA bodies": a subcompartment of the endoplasmic reticulum. (1993) (56)
- Active recycling of yeast Golgi mannosyltransferase complexes through the endoplasmic reticulum. (2000) (55)
- Unconventional secretion of FABP4 by endosomes and secretory lysosomes (2018) (54)
- TFG facilitates outer coat disassembly on COPII transport carriers to promote tethering and fusion with ER–Golgi intermediate compartments (2017) (54)
- Ent3p and Ent5p exhibit cargo-specific functions in trafficking proteins between the trans-Golgi network and the endosomes in yeast. (2007) (53)
- The ER-Golgi intermediate compartment feeds the phagophore membrane (2014) (53)
- Distinct processes mediate glycoprotein and glycopeptide export from the endoplasmic reticulum in Saccharomyces cerevisiae. (1992) (50)
- Coatomer-rich endoplasmic reticulum. (1994) (49)
- Avl9p, a member of a novel protein superfamily, functions in the late secretory pathway. (2007) (47)
- COPII and the regulation of protein sorting in mammals (2012) (46)
- Coincident localization of secretory and plasma membrane proteins in organelles of the yeast secretory pathway (1988) (45)
- Interorganelle transfer and glycosylation of yeast invertase in vitro. (1986) (43)
- Extracellular Vesicles and Cancer: Caveat Lector (2018) (43)
- Vesicle budding from endoplasmic reticulum. (2002) (43)
- ER-Golgi transport defects are associated with mutations in the Sed5p-binding domain of the COPII coat subunit, Sec24p. (2005) (42)
- Charting the Secretory Pathway in a Simple Eukaryote (2010) (42)
- TANGO1 and SEC12 are copackaged with procollagen I to facilitate the generation of large COPII carriers (2018) (41)
- SEC23-SEC31 the Interface Plays Critical Role for Export of Procollagen from the Endoplasmic Reticulum (2012) (40)
- Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin. (2011) (39)
- Sorting Signals That Mediate Traffic of Chitin Synthase III between the TGN/Endosomes and to the Plasma Membrane in Yeast (2012) (38)
- Defective plasma membrane assembly in yeast secretory mutants (1984) (38)
- Sec59 encodes a membrane protein required for core glycosylation in Saccharomyces cerevisiae (1989) (38)
- Uncoupled Packaging of Targeting and Cargo Molecules during Transport Vesicle Budding from the Endoplasmic Reticulum (*) (1995) (38)
- Site of catabolite inactivation (1994) (36)
- Molecular machinery required for protein transport from the endoplasmic reticulum to the golgi complex (1990) (36)
- A CLN6-CLN8 complex recruits lysosomal enzymes at the ER for Golgi transfer (2019) (36)
- Phosphoregulatory protein 14-3-3 facilitates SAC1 transport from the endoplasmic reticulum (2015) (35)
- ALG-2 Attenuates COPII Budding In Vitro and Stabilizes the Sec23/Sec31A Complex (2013) (35)
- Vps10p cycles between the TGN and the late endosome via the plasma membrane in clathrin mutants. (2002) (34)
- Membrane fusion: Ready ⃛ aim ⃛ fire! (1998) (33)
- Biogenesis of autophagosomal precursors for LC3 lipidation from the ER-Golgi intermediate compartment (2015) (33)
- Molecular Mechanism of Protein Folding in the Cell (2011) (33)
- The use of liposomes to study COPII- and COPI-coated vesicle formation and membrane protein sorting. (2000) (33)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Regulation of LC3 lipidation by the autophagy-specific class III phosphatidylinositol-3 kinase complex (2019) (32)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- Differential Trafficking and Timed Localization of Two Chitin Synthase Proteins , Chs 2 p and Chs 3 p (2002) (30)
- Reforming research assessment (2013) (29)
- Advancing research (2014) (29)
- Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates (2021) (28)
- Isolation of secretory vesicles from Saccharomyces cerevisiae. (1987) (28)
- Lasker Basic Medical Research Award. SEC mutants and the secretory apparatus. (2002) (28)
- Translocation gets a push (1994) (28)
- 4 Heat Shock Cognate Proteins and Polypeptide Translocation Across the Endoplasmic Reticulum Membrane (1994) (27)
- BAR Domains Go on a Bender (2004) (27)
- Isolation of glucose-containing high-mannose glycoprotein core oligosaccharides. (1984) (26)
- Insights into Golgi function through mutants in yeast and animal cells (1997) (24)
- Calcium control of Saccharomyces cerevisiae actin assembly (1982) (24)
- Discovery of the cellular and molecular basis of cholesterol control (2013) (23)
- The ins and outs of presenilin 1 membrane topology. (2004) (23)
- The eLife approach to peer review (2013) (22)
- Editorial Expression of Concern: A bifunctional tRNA import receptor from Leishmania mitochondria (2010) (22)
- Reconstitution of protein transport using broken yeast spheroplasts. (1989) (22)
- Two distinct subfractions in isolated Saccharomyces cerevisiae plasma membranes (1983) (21)
- Glycosyl-phosphatidylinositol anchor attachment in a yeast in vitro system. (1997) (21)
- New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells (2019) (20)
- Neurodegeneration-associated mutant TREM2 proteins abortively cycle between the ER and ER–Golgi intermediate compartment (2017) (19)
- A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum (2011) (19)
- Mitotic Misregulation and Human Aging (2000) (18)
- Regulated Oligomerization Induces Uptake of a Membrane Protein into COPII Vesicles Independent of Its Cytosolic Tail (2014) (18)
- Polynucleotide ligase and phiX174 single strand synthesis. (1971) (18)
- Merging cultures in the study of membrane traffic (2004) (17)
- Fatty-acid binding protein 5 modulates the SAR1 GTPase cycle and enhances budding of large COPII cargoes (2019) (17)
- A mechanism for differential sorting of the planar cell polarity proteins Frizzled6 and Vangl2 at the trans-Golgi network (2018) (16)
- Interleaflet clear space is reduced in the membrane of COP I and COP II-coated buds/vesicles. (1996) (16)
- Cargo sorting into multivesicular bodies in vitro (2009) (16)
- Regulation of membrane traffic in the secretory pathway. (1994) (16)
- Cell biology: A channel for protein waste (2004) (15)
- Phosphorylation of Chs2p regulates interaction with COPII (2013) (14)
- Polypeptide translocation machinery of the yeast endoplasmic reticulum (1996) (14)
- Small sequence variations between two mammalian paralogs of the small GTPase SAR1 underlie functional differences in coat protein complex II assembly (2020) (14)
- Polypeptide Translocation: A Pretty Picture Is Worth a Thousand Words (1996) (14)
- Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase (2021) (14)
- Editorial Expression of Concern and Corrections (2008) (13)
- Yeast secretory mutants: isolation and characterization. (1983) (13)
- Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D1 (2021) (13)
- [64] Yeast secretory mutants: Isolation and characterization (1983) (13)
- Coat proteins and selective protein packaging into transport vesicles. (1995) (12)
- Replication of bacteriophage M13. 3. Identification of the intracellular single-straned DNA. (1969) (12)
- Promoter Recognition As Measured by Binding of Polymerase to Nontemplate Strand Oligonucleotide (1997) (11)
- Coordinating a new approach to basic research into Parkinson’s disease (2019) (10)
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- Using Many Social Media Platforms Linked With Depression, Anxiety Risk (2017) (9)
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- Profile of Aziz Sancar. (2005) (8)
- Distinct stages in the recognition, sorting, and packaging of proTGFα into COPII-coated transport vesicles (2016) (8)
- Launching eLife, Part 1 (2012) (8)
- Cell-free Generation of COPII-coated Procollagen I Carriers. (2017) (8)
- Profile of Alec J. Jeffreys. (2006) (8)
- Characterization and comparison of metal accumulation in two Escherichia coli strains expressing either CopA or MntA, heavy metal-transporting bacterial P-type adenosine triphosphatases (2004) (7)
- Cell biology. BAR domains go on a bender. (2004) (7)
- PNAS allows authors to keep copyright (2009) (7)
- Use of sec mutants to define intermediates in protein transport from endoplasmic reticulum. (1992) (6)
- How sterols regulate protein sorting and traffic (2007) (6)
- Clathrin: a matter of life or death? (1988) (6)
- A year in the life of eLife (2013) (6)
- An interview with Randy Schekman and Thomas Südhof. (2014) (6)
- PNAS takes action regarding breach of NIH embargo policy on a PNAS paper (2009) (5)
- Retraction for Liu et al., Production and secretion of fatty acids in genetically engineered cyanobacteria (2010) (5)
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- Editorial Expression of Concern: Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichiapastoris (2010) (3)
- APA to Provide Framework to Evaluate Mobile Health Apps (2017) (3)
- Profile of Xiaodong Wang. (2006) (3)
- Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers (2022) (3)
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- Purification of yeast Sec23 protein by complementation of mutant cell lysates deficient in endoplasmic reticulum-to-Golgi transport. (1992) (2)
- Recognizing the importance of new tools and resources for research (2015) (2)
- Profile of Randy Schekman: Reflections on his first year as PNAS Editor-in-Chief (2008) (2)
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- Researchers Develop New Method for Tracking Serotonin Transport (2016) (0)
- To Minimize Medication Withdrawal, Taper Slowly (2021) (0)
- Research Identifies Gene Linked to Cannabis-Induced Psychosis (2016) (0)
- Journal Digest: IRT; Motivational Therapy; Mental Health Apps; and More (2023) (0)
- Two-Part Assessment May Help Predict Suicidal Behavior, Study Finds (2015) (0)
- Genetic Variant May Foretell Cognitive Response to Antipsychotics (2018) (0)
- Verbal De-Escalation May Not Be Best for Children With Aggressive Behavior (2019) (0)
- New Analysis Suggests There Is No Such Thing as Harmless Head Contact in Football (2019) (0)
- Caplyta Now Approved for Bipolar Depression (2022) (0)
- Editors Select AJP Articles That Stood Out in 2016 (2017) (0)
- APA Releases ‘Guideline Watch’ for Dementias (2015) (0)
- Integrated Care Can Be Improved By Better Understanding of Culture (2015) (0)
- NIMH Director Describes Ways to Better Target Therapy (2020) (0)
- NIH Partners With Industry to Stem Opioid Crisis (2017) (0)
- Journal Digest: Discrimination and Alcohol Abuse; COVID-19 Education and Stress; Bumetanide and ASD Symptoms; OUD Patients and Hospitalization (2020) (0)
- Recovery After Disaster Involves Reaching Out—and Reaching In (2017) (0)
- Alcohol Misuse No Reason to Avoid Exposure Therapy for PTSD (2019) (0)
- FDA Database Supports Antidepressant Actions of Four Drugs (2017) (0)
- Growing Recognition of Prevalence of Disorders Brought on by Prenatal Alcohol Exposure (2015) (0)
- Alzheimer’s Blood Test Shows Clinical Potential (2020) (0)
- Brain Region That Produces Spinal Fluid Implicated in Psychosis (2019) (0)
- People With Psychiatric Illness Tend to Partner With Each Other (2016) (0)
- Less Than Half of Seniors With Dementia Get Cognitive Testing (2015) (0)
- Researchers Make Advances in Neural Stem Cell Therapy (2016) (0)
- Innovation Zone Adds New Touches to a Familiar Formula (2020) (0)
- Smoking Cessation App That Teaches Acceptance Shows Promise (2020) (0)
- Study Finds Selenium, Vitamin E Do Not Prevent Dementia (2017) (0)
- Nonprofit Matches Volunteer Physicians With Communities in Need (2017) (0)
- Experts Present Protocol for Accelerated Antidepressant Trials (2022) (0)
- Amyloid-Busting Antibody Wins FDA Approval, but Courts Controversy (2021) (0)
- Psychiatrists Can Do More to Help Patients Quit Smoking (2019) (0)
- Updated Rules for Human Research Become Effective in January (2018) (0)
- NIDA Sessions to Examine Treating Substance Use During Pandemic (2022) (0)
- Tools to Help Burnout, Attention Problems Among Winners at 2019 APA Innovation Lab (2019) (0)
- Virtual Reality May Soon Become Clinical Reality in Psychosis Care (2018) (0)
- Acting May Help Break Down Barriers for Patients With Mental Illness (2016) (0)
- New Genetic Analysis Provides Clues to Schizophrenia Origins (2020) (0)
- FDA’s Streamlined Health App Approval: Better for Patients or Companies? (2019) (0)
- U.S. Experiences Uptick In Rates of Suicide (2016) (0)
- EduTours Will Give Inside Look at Two Major N.Y. Institutions (2018) (0)
- Computer-Based Tool Can Offer Rapid Screening After TBI (2016) (0)
- Session to Separate Fact From Fiction on Gun Violence, Mental Health Link (2018) (0)
- Mental Health Apps Miss the Mark on Usability Standards, Study Shows (2019) (0)
- Free Service Connects Clinicians With Perinatal Psychiatry Experts (2019) (0)
- Genetic Analysis Identifies Possible Acamprosate Biomarker (2014) (0)
- BBRF Celebrates 30-Year Anniversary While Honoring Innovative Researchers (2017) (0)
- Emergency Department Intervention May Reduce Suicide Attempts in At-Risk Patients (2017) (0)
- Exposure to Alcohol, Cannabis in Womb Can Have Long-Term Consequences (2020) (0)
- Translocation Gets a Push Minireview (2003) (0)
- (chitin synthase/zymogen activation/asymmetric membrane asse (2016) (0)
- Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes (2023) (0)
- Cell and Developmental Biology (2009) (0)
- Editorial Board (1981) (0)
- Chemical disaggregation of alpha-synuclein fibrils as a therapy for synucleinopathies. (2023) (0)
- Initiation of DNA Synthesis: Requires RNA Synthesis Resistant to Rifampicin* Synthesis of 4x174 Replicative Form (dd gene product/dnaB gene product/Ml3 DNA/spermidine) (1979) (0)
- RNA Synthesis Initiates InVitro Conversion ofM113DNA toItsReplicativ (1972) (0)
- Saylor.org BIO301: UC Berkeley's "Membrane Transport Permeases and Channels" (2011) (0)
- Editorial Board (2010) (0)
- Invertase 3-Galactosidase HybridProteins FailToBeTransported fromtheEndoplasmic Reticulum inSaccharomyces cerevisiae (1984) (0)
- Editorial Board (2013) (0)
- Meeting Abstracts of the first meeting of the American Society for Intercellular Communication 2021 (2022) (0)
- Topology andFunctional DomainsofSec63p, an Endoplasmic Reticulum MembraneProtein Required forSecretory Protein Translocation (1992) (0)
- The Journal of Cell Biology: Letter from the editors (1999) (0)
- Lyticase: Endoglucanase andProtease Activities ThatAct Together inYeast Cell Lysis (1980) (0)
- Characterization of Thylakoid Immunophilins in Arabidopsis By Veder Joel García A dissertation submitted in partial satisfaction of the requirements for the degree of Doctor of Philosophy (2013) (0)
- ChemoresistanceIsomerase PDIA5 To Modulate Requires the α Transcription Factor ATF6 Endoplasmic Reticulum Stress-Activated (2014) (0)
- Progress and promise (2019) (0)
- Change is good: life outside the nucleus (2009) (0)
- Editorial Expression of Concern for multiple articles (2008) (0)
- Saylor.org BIO301: UC Berkeley's "Cell Communication" (2011) (0)
- Selective sorting of microRNAs into exosomes by phase-1 separated YBX 1 condensates 2 Alternative title : Condensation of YBX 1 into processing bodies reveals mechanisms for 3 selective sorting of microRNAs into exosomes 4 (2021) (0)
- Letter From The Editors (1999) (0)
- Initiation ofDNA Synthesis: Synthesis ofoX174Replicative Form Requires RNA Synthesis Resistant toRifampicin* (dnaAgeneproduct/dnaB geneproduct/M13 DNA/spermidine) (1972) (0)
- Annexin A6 mediates calcium-dependent secretion of exosomes (2022) (0)
- D.C. Psychiatric Society Hosts Panel On Nutrition and Psychiatry (2017) (0)
- Saylor.org BIO301: UC Berkeley's "Transport Into and Out of Nucleus II and Intracellular Transport..." (2011) (0)
- Enlarged Crystalline Patches on the Plasma Membrane of Yeast Protoplasts (1980) (0)
- Retraction for Venters et al., A new mechanism of neurodegeneration: A proinflammatory cytokine inhibits receptor signaling by a survival peptide (2009) (0)
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