Raymond Dwek
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Most Influential Person Now
British chemist
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Chemistry
Raymond Dwek's Degrees
- PhD Chemistry University of Oxford
Why Is Raymond Dwek Influential?
(Suggest an Edit or Addition)According to Wikipedia, Raymond Allen Dwek CBE FRS FRSC is a scientist at the University of Oxford and co-founder of the biotechnology company Oxford GlycoSciences Ltd. Biography Dwek was educated at Carmel College, and the University of Manchester, where he studied chemistry . He then went to Oxford University and Lincoln College, Oxford, where he completed his DPhil in physical chemistry in 1966. He became Professor of Glycobiology in 1988 in the Department of Biochemistry. He is an emeritus fellow of Exeter College, Oxford and co-director of the Oxford Glycobiology Institute, which he founded in 1991. From 2000 to 2006, he was also head of the Department of Biochemistry. He was a member of the Board of Scientific Governors at The Scripps Research Institute from 2007 to 2015 and an Institute Professor there in 2008. Dwek was President of the Institute of Biology from 2008 to 2010, overseeing the merger with the UK Science Federation to form the Royal Society of Biology. Dwek was the Kluge Chair of Technology and Society at the Library of Congress in the US in 2007. He was scientific advisor to the presidents of Ben-Gurion University of the Negev in Israel from 1997 to 2019, where he helped to build the National Institute of Biotechnology in the Negev. He was also scientific advisor to the Institute of Biochemistry in Bucharest. Dwek was co-chair of the UK/Israel Science Council from 2012 to 2017. Since 2013, Dwek has been a member of the scientific governing board of the newly established ShanghaiTech University.
Raymond Dwek's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Glycobiology: Toward Understanding the Function of Sugars. (1996) (2334)
- Glycosylation and the immune system. (2001) (1386)
- The impact of glycosylation on the biological function and structure of human immunoglobulins. (2007) (1185)
- Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG (1985) (1102)
- Crystal Structure of a Neutralizing Human IgG Against HIV-1: A Template for Vaccine Design (2001) (875)
- Biochemistry and Molecular Biology of Gelatinase B or Matrix Metalloproteinase-9 (MMP-9) (2002) (848)
- Glycobiology (2018) (775)
- Glycosylation changes of IgG associated with rheumatooid arthritis can activate complement via the mannose-binding protein (1995) (751)
- Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition (2003) (745)
- Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis (2000) (713)
- The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120 (2002) (700)
- Concepts and principles of O-linked glycosylation. (1998) (697)
- Glycosyl-phosphatidylinositol moiety that anchors Trypanosoma brucei variant surface glycoprotein to the membrane. (1988) (586)
- Antibodies inhibit prion propagation and clear cell cultures of prion infectivity (2001) (519)
- A rapid high-resolution high-performance liquid chromatographic method for separating glycan mixtures and analyzing oligosaccharide profiles. (1996) (459)
- Statistical analysis of the protein environment of N-glycosylation sites: implications for occupancy, structure, and folding. (2003) (446)
- N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis. (1994) (427)
- HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software. (2008) (424)
- The Mannose Receptor Mediates Dengue Virus Infection of Macrophages (2008) (420)
- Glycosylation: heterogeneity and the 3D structure of proteins. (1997) (407)
- The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives (2003) (404)
- The Glycosylation and Structure of Human Serum IgA1, Fab, and Fc Regions and the Role of N-Glycosylation on Fcα Receptor Interactions* (1998) (394)
- Targeting glycosylation as a therapeutic approach (2002) (393)
- Emerging Principles for the Therapeutic Exploitation of Glycosylation (2014) (375)
- Comparison of the methods for profiling glycoprotein glycans--HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study. (2007) (365)
- Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG. (2007) (359)
- Molecular Mechanical and Molecular Dynamic Simulations of Glycoproteins and Oligosaccharides. 1. GLYCAM_93 Parameter Development (1995) (355)
- Conformational studies of oligosaccharides and glycopeptides: complementarity of NMR, X-ray crystallography, and molecular modelling. (2002) (355)
- Complete structure of the glycosyl phosphatidylinositol membrane anchor of rat brain Thy-1 glycoprotein (1988) (353)
- Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase (2004) (346)
- Use of targeted glycoproteomics to identify serum glycoproteins that correlate with liver cancer in woodchucks and humans. (2005) (345)
- Sequencing of N-linked oligosaccharides directly from protein gels: in-gel deglycosylation followed by matrix-assisted laser desorption/ionization mass spectrometry and normal-phase high-performance liquid chromatography. (1997) (330)
- Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens (2010) (320)
- Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirimycin. (1997) (316)
- Secretory IgA N- and O-Glycans Provide a Link between the Innate and Adaptive Immune Systems* (2003) (305)
- Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis. (2003) (304)
- Inhibition of HIV replication by amino‐sugar derivatives (1988) (297)
- Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease (2007) (297)
- Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: implications for the development of broad spectrum anti-hepatitis virus agents. (1999) (295)
- Glycoforms modify the dynamic stability and functional activity of an enzyme. (1994) (283)
- Glycoprotein Structural Genomics: Solving the Glycosylation Problem (2007) (282)
- GlycoBase and autoGU: tools for HPLC-based glycan analysis (2008) (274)
- Altered glycosylation pattern allows the distinction between prostate-specific antigen (PSA) from normal and tumor origins. (2003) (273)
- Age-related galactosylation of the N-linked oligosaccharides of human serum IgG (1988) (267)
- Glycoproteins: glycan presentation and protein-fold stability. (1999) (266)
- Glycosylation differences between the normal and pathogenic prion protein isoforms. (1999) (265)
- Agalactosyl glycoforms of IgG autoantibodies are pathogenic. (1994) (261)
- α‐Glucosidase inhibitors as potential broad based anti‐viral agents (1998) (260)
- Aminosugar derivatives as potential anti-human immunodeficiency virus agents. (1988) (252)
- Proposal for a standard system for drawing structural diagrams of N‐ and O‐linked carbohydrates and related compounds (2009) (246)
- Exploiting the defensive sugars of HIV-1 for drug and vaccine design (2007) (243)
- Roles for glycosylation of cell surface receptors involved in cellular immune recognition. (1999) (242)
- Function and glycosylation of plant-derived antiviral monoclonal antibody (2003) (242)
- Inhibition of glycosphingolipid biosynthesis: application to lysosomal storage disorders. (2000) (241)
- Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin. (1999) (241)
- Structural Characterization of the 1918 Influenza Virus H1N1 Neuraminidase (2008) (239)
- Contrasting IgG structures reveal extreme asymmetry and flexibility. (2002) (233)
- Sustained therapeutic effects of oral miglustat (Zavesca, N-butyldeoxynojirimycin, OGT 918) in type I Gaucher disease (2004) (232)
- The Glycan Shield of HIV Is Predominantly Oligomannose Independently of Production System or Viral Clade (2011) (219)
- Detailed structural analysis of N-glycans released from glycoproteins in SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions. (2006) (218)
- GALACTOSYLATION OF IgG ASSOCIATED OLIGOSACCHARIDES: REDUCTION IN PATIENTS WITH ADULT AND JUVENILE ONSET RHEUMATOID ARTHRITIS AND RELATION TO DISEASE ACTIVITY (1988) (212)
- Effector functions of a monoclonal aglycosylated mouse IgG2a: binding and activation of complement component C1 and interaction with human monocyte Fc receptor. (1985) (205)
- Antiviral Effects of an Iminosugar Derivative on Flavivirus Infections (2002) (201)
- A strategy to reveal potential glycan markers from serum glycoproteins associated with breast cancer progression. (2008) (200)
- Analysis of glycoprotein-associated oligosaccharides. (1993) (198)
- Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses. (2005) (198)
- Storage solutions: treating lysosomal disorders of the brain (2005) (197)
- Tissue‐specific N‐glycosylation, site‐specific oligosaccharide patterns and lentil lectin recognition of rat Thy‐1. (1987) (196)
- Structural and quantitative analysis of N-linked glycans by matrix-assisted laser desorption ionization and negative ion nanospray mass spectrometry. (2008) (191)
- Variations in oligosaccharide-protein interactions in immunoglobulin G determine the site-specific glycosylation profiles and modulate the dynamic motion of the Fc oligosaccharides. (1997) (191)
- A comparative analysis of disease-associated changes in the galactosylation of serum IgG. (1989) (191)
- Conformation-Independent Binding of Monoglucosylated Ribonuclease B to Calnexin (1997) (189)
- Accumulation of Glycosphingolipids in Niemann-Pick C Disease Disrupts Endosomal Transport* (2004) (186)
- Towards complete analysis of the platelet proteome (2002) (185)
- Recognition of carbohydrate by major histocompatibility complex class I- restricted, glycopeptide-specific cytotoxic T lymphocytes (1994) (185)
- Concepts and principles of glycobiology (1993) (184)
- Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteins. (2004) (182)
- Secretion of human hepatitis B virus is inhibited by the imino sugar N-butyldeoxynojirimycin. (1994) (179)
- An analytical and structural database provides a strategy for sequencing O-glycans from microgram quantities of glycoproteins. (2002) (177)
- Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling. (2004) (175)
- Novel serum biomarker candidates for liver fibrosis in hepatitis C patients. (2007) (174)
- The Hemopexin and O-Glycosylated Domains Tune Gelatinase B/MMP-9 Bioavailability via Inhibition and Binding to Cargo Receptors* (2006) (174)
- Structure, biosynthesis, and function of glycosylphosphatidylinositols. (1990) (174)
- N-butyldeoxygalactonojirimycin inhibits glycolipid biosynthesis but does not affect N-linked oligosaccharide processing. (1994) (173)
- Extensive analysis of the human platelet proteome by two‐dimensional gel electrophoresis and mass spectrometry (2004) (163)
- Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA. (2006) (162)
- Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals (2007) (160)
- A strategy for the comparative analysis of serum proteomes for the discovery of biomarkers for hepatocellular carcinoma (2003) (160)
- The Glycosylation of the Complement Regulatory Protein, Human Erythrocyte CD59* (1997) (158)
- Glycosylation Changes on Serum Glycoproteins in Ovarian Cancer May Contribute to Disease Pathogenesis (2009) (158)
- The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy (2009) (157)
- Treatment with miglustat reverses the lipid-trafficking defect in Niemann–Pick disease type C (2004) (154)
- The C1q receptor site on immunoglobulin G (1980) (150)
- Human Serum IgM Glycosylation (2005) (150)
- The alpha-glucosidase inhibitor N-butyldeoxynojirimycin inhibits human immunodeficiency virus entry at the level of post-CD4 binding (1995) (148)
- Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases (2006) (145)
- Treatment of chronic hepadnavirus infection in a woodchuck animal model with an inhibitor of protein folding and trafficking (1998) (145)
- Detailed glycan analysis of serum glycoproteins of patients with congenital disorders of glycosylation indicates the specific defective glycan processing step and provides an insight into pathogenesis. (2003) (144)
- Effects of the imino sugar N-butyldeoxynojirimycin on the N-glycosylation of recombinant gp120. (1993) (143)
- Prion glycoprotein: structure, dynamics, and roles for the sugars. (2001) (141)
- Binding of sugar ligands to Ca(2+)-dependent animal lectins. I. Analysis of mannose binding by site-directed mutagenesis and NMR. (1994) (140)
- Therapeutic applications of imino sugars in lysosomal storage disorders. (2003) (139)
- Study of the Mechanism of Antiviral Action of Iminosugar Derivatives against Bovine Viral Diarrhea Virus (2001) (139)
- Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus (2007) (139)
- Cell-type-specific and site-specific N-glycosylation of type I and type II human tissue plasminogen activator. (1989) (138)
- Two edged role of mannose binding lectin in rheumatoid arthritis: a cross sectional study. (2000) (135)
- N-butyldeoxygalactonojirimycin: a more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin, in vitro and in vivo. (2000) (135)
- Mannan binding lectin and its interaction with immunoglobulins in health and in disease. (2006) (134)
- Characterization of the cross-reacting determinant (CRD) of the glycosyl-phosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoprotein. (1988) (131)
- Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity. (1999) (131)
- Oligosaccharide sequencing technology (1997) (130)
- "Internal residue loss": rearrangements occurring during the fragmentation of carbohydrates derivatized at the reducing terminus. (2002) (128)
- Site-specific glycosylation of human immunoglobulin G is altered in four rheumatoid arthritis patients. (1996) (127)
- Nuclear Magnetic Resonance in Biochemistry: Applications to Enzyme Systems (1973) (127)
- Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion. (1997) (127)
- Molecular mechanism of lipopeptide presentation by CD1a. (2005) (126)
- NMR in Biological Research: Peptides and Proteins (1978) (125)
- The O-linked glycosylation of secretory/shed MUC1 from an advanced breast cancer patient's serum. (2008) (124)
- Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis (2000) (122)
- Proton relaxation enhancement (PRE) in biochemistry: A critical survey (1979) (121)
- The β1 → 2‐d‐xylose and α1 → 3‐l‐fucose substituted N‐linked oligosaccharides from Erythrina cristagalli lectin (1987) (121)
- Extensive Glycosphingolipid Depletion in the Liver and Lymphoid Organs of Mice Treated with N-Butyldeoxynojirimycin* (1997) (120)
- Glycosylation and the complement system. (2002) (119)
- NSAIDs increase survival in the Sandhoff disease mouse: Synergy with N‐butyldeoxynojirimycin (2004) (118)
- Complement regulation at the molecular level: the structure of decay-accelerating factor. (2004) (118)
- High resolution1H- and13C-N.M.R spectra ofD-glucopyranose, 2-acetamido-2-deoxy-D-glucopyranose, and related compounds in aqueous media (1977) (118)
- Enhanced survival in Sandhoff disease mice receiving a combination of substrate deprivation therapy and bone marrow transplantation. (2001) (115)
- The high degree of internal flexibility observed for an oligomannose oligosaccharide does not alter the overall topology of the molecule. (1998) (115)
- Genes contributing to prion pathogenesis. (2008) (114)
- Altered glycosylation of proteins in cancer: what is the potential for new anti-tumour strategies. (2008) (114)
- Mutations at Critical N-Glycosylation Sites Reduce Tyrosinase Activity by Altering Folding and Quality Control* (2000) (114)
- Structure of the major carbohydrate fragment of the Leishmania donovani lipophosphoglycan. (1987) (114)
- A statistical analysis of N- and O-glycan linkage conformations from crystallographic data. (1999) (113)
- Human Follicular Lymphoma Cells Contain Oligomannose Glycans in the Antigen-binding Site of the B-cell Receptor* (2007) (113)
- EUROCarbDB: An open-access platform for glycoinformatics (2010) (113)
- Hepatitis B Virus Requires Intact Caveolin-1 Function for Productive Infection in HepaRG Cells (2009) (111)
- Glycobiology: more functions for oligosaccharides (1995) (111)
- N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with changes in antibody recognition of the V1/V2 region of gp120 (1996) (110)
- Matrix remodelling enzymes, the protease cascade and glycosylation. (2001) (109)
- Inhibition of substrate synthesis as a strategy for glycolipid lysosomal storage disease therapy (2001) (109)
- Structural characterization of the asparagine-linked oligosaccharides from Trypanosoma brucei type II and type III variant surface glycoproteins. (1991) (107)
- Glycobiology: "towards understanding the function of sugars". (1996) (107)
- Recovery of intact 2-aminobenzamide-labeled O-glycans released from glycoproteins by hydrazinolysis. (2002) (107)
- Increased Levels of Galactose-Deficient Anti-Gal Immunoglobulin G in the Sera of Hepatitis C Virus-Infected Individuals with Fibrosis and Cirrhosis (2007) (105)
- Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody. (2004) (105)
- Agalactosyl IgG in inflammatory bowel disease: correlation with C-reactive protein. (1990) (104)
- Cell-specific Glycoforms of Sialoadhesin and CD45 Are Counter-receptors for the Cysteine-rich Domain of the Mannose Receptor* (1999) (102)
- Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression. (2005) (101)
- N-glycosylation and in vitro enzymatic activity of human recombinant tissue plasminogen activator expressed in Chinese hamster ovary cells and a murine cell line. (1989) (101)
- Glycobiology: “Towards Understanding the Function of Sugars” (1995) (101)
- Glucosylceramide modulates membrane traffic along the endocytic pathway Published, JLR Papers in Press, August 16, 2002. DOI 10.1194/jlr.M200232-JLR200 (2002) (101)
- Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2 (2009) (101)
- A Glycoconjugate Antigen Based on the Recognition Motif of a Broadly Neutralizing Human Immunodeficiency Virus Antibody, 2G12, Is Immunogenic but Elicits Antibodies Unable To Bind to the Self Glycans of gp120 (2008) (100)
- Rapid, sensitive sequencing of oligosaccharides from glycoproteins. (1997) (100)
- Protein-protein interactions: modeling the hepatitis C virus ion channel p7. (2006) (100)
- The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin1 (2004) (100)
- The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator. (1995) (99)
- Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein (2010) (99)
- The Glycosylation of the Influenza A Virus Hemagglutinin by Mammalian Cells (1997) (99)
- Conformational transitions in N-linked oligosaccharides. (1986) (98)
- Sugar-mediated ligand-receptor interactions in the immune system. (2004) (97)
- Glycosylation of serum ribonuclease 1 indicates a major endothelial origin and reveals an increase in core fucosylation in pancreatic cancer. (2007) (97)
- A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI‐activated platelets: Involvement of G6f, a novel platelet Grb2‐binding membrane adapter (2006) (97)
- Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin. (1999) (96)
- Glycosphingolipid lysosomal storage diseases: therapy and pathogenesis (2002) (96)
- Effects of glycosylation on protein structure and dynamics in ribonuclease B and some of its individual glycoforms. (1993) (93)
- The conformational effects of N-glycosylation on the tailpiece from serum IgM. (1991) (93)
- Structural analysis of the N-glycans from human immunoglobulin A1: comparison of normal human serum immunoglobulin A1 with that isolated from patients with rheumatoid arthritis. (1994) (92)
- Differential glycosylation of polymeric and monomeric IgA: a possible role in glomerular inflammation in IgA nephropathy. (2006) (92)
- Solution conformations of N-linked oligosaccharides. (1987) (92)
- Fast sequencing of oligosaccharides: the reagent-array analysis method. (1992) (92)
- Glycan structures of ocular surface mucins in man, rabbit and dog display species differences (2008) (90)
- Glycobiology: 'the function of sugar in the IgG molecule'. (1995) (89)
- Evidence that N-linked glycosylation is necessary for hepatitis B virus secretion. (1995) (88)
- Structure of the phosphosaccharide-inositol core of the Leishmania donovani lipophosphoglycan. (1989) (88)
- Protein surface oligosaccharides and protein function (1994) (86)
- Probes for the conformational transitions of phosphorylase b. Effect of ligands studied by proton relaxation enhancement, fluorescence and chemical reactivities. (1971) (86)
- Antiviral Effect ofN-Butyldeoxynojirimycin against Bovine Viral Diarrhea Virus Correlates with Misfolding of E2 Envelope Proteins and Impairment of Their Association into E1-E2 Heterodimers (2001) (85)
- Correction: The Mannose Receptor Mediates Dengue Virus Infection of Macrophages (2008) (85)
- Effects of N-glycosylation on in vitro activity of Bowes melanoma and human colon fibroblast derived tissue plasminogen activator. (1989) (85)
- Separation‐based Glycoprofiling Approaches using Fluorescent Labels (2007) (84)
- Sugar printing rheumatic diseases: a potential method for disease differentiation using immunoglobulin G oligosaccharides. (1999) (84)
- Analysis of glycosylation changes in IgG using lectins. (1990) (83)
- O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organization of the enzyme. (2000) (83)
- An iminosugar with potent inhibition of dengue virus infection in vivo. (2013) (83)
- Neutral N-glycans in adult rat brain tissue--complete characterisation reveals fucosylated hybrid and complex structures. (1998) (83)
- N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with impaired gp120 shedding and gp41 exposure (1996) (82)
- Unraveling adaptive evolution: how a single point mutation affects the protein coregulation network (2006) (82)
- Reversible infertility in male mice after oral administration of alkylated imino sugars: A nonhormonal approach to male contraception (2002) (80)
- Glycosylation and prion protein. (2002) (80)
- Structure and dynamics in oligomannose-type oligosaccharides. (1987) (80)
- Tissue specific O-linked glycosylation of the neural cell adhesion molecule (N-CAM). (1989) (80)
- Solution structure of the glycosylphosphatidylinositol membrane anchor glycan of Trypanosoma brucei variant surface glycoprotein. (1989) (79)
- Effects of glycosylation on protein conformation and amide proton exchange rates in RNase B (1992) (79)
- Sialylated N-glycans in adult rat brain tissue--a widespread distribution of disialylated antennae in complex and hybrid structures. (1998) (78)
- 1-N-glycyl beta-oligosaccharide derivatives as stable intermediates for the formation of glycoconjugate probes. (1992) (78)
- O-linked oligosaccharides from human serum immunoglobulin A1. (1989) (78)
- Comparisons of ring-current shifts calculated from the crystal structure of egg white lysozyme of hen with the proton nuclear magnetic resonance spectrum of lysozyme in solution. (1980) (78)
- Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum alpha-glucosidase inhibition. (2008) (77)
- Controlled glycosylation of therapeutic antibodies in plants. (2004) (77)
- Sugar Determines Antibody Activity (2006) (77)
- Structure of an antibody combining site by magnetic resonance (1977) (77)
- Immunoglobulin G as a glycoprotein. (1986) (77)
- Beneficial effects of substrate reduction therapy in a mouse model of GM1 gangliosidosis. (2008) (76)
- Peptide anchor residue glycosylation: effect on class I major histocompatibility complex binding and cytotoxic T lymphocyte recognition (1995) (76)
- Improved outcome of N-butyldeoxygalactonojirimycin-mediated substrate reduction therapy in a mouse model of Sandhoff disease (2004) (76)
- Preparation, biochemical characterization and biological properties of radiolabelled N-alkylated deoxynojirimycins. (2002) (74)
- Tyrosinase folding and copper loading in vivo: a crucial role for calnexin and alpha-glucosidase II. (1999) (74)
- Inhibition of N-Glycan Processing in B16 Melanoma Cells Results in Inactivation of Tyrosinase but Does Not Prevent Its Transport to the Melanosome* (1997) (73)
- Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans. (2010) (73)
- Glycosylation of human pancreatic ribonuclease: differences between normal and tumor states. (2003) (72)
- Novel sequential solid-phase synthesis of N-linked glycopeptides from natural sources (1998) (71)
- The lanthanide cations as probes in biological systems. Proton relaxation enhancement studies for model systems and lysozyme. (1971) (70)
- Structural aspects of glycomes with a focus on N-glycosylation and glycoprotein folding. (2006) (70)
- Synthesis and Biological Characterisation of Novel N‐Alkyl‐Deoxynojirimycin α‐Glucosidase Inhibitors (2009) (70)
- Treatment of hepatitis B virus-infected cells with alpha-glucosidase inhibitors results in production of virions with altered molecular composition and infectivity. (2007) (69)
- 500-picosecond molecular dynamics in water of the Man alpha 1----2Man alpha glycosidic linkage present in Asn-linked oligomannose-type structures on glycoproteins. (1990) (69)
- Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody. (2007) (68)
- Tertiary structure in N-linked oligosaccharides. (1987) (68)
- Localization and characterization of polysialic acid-containing N-linked glycans from bovine NCAM. (2002) (67)
- The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12. (2003) (67)
- Development of a single column method for the separation of lipid- and protein-derived oligosaccharides. (2009) (67)
- Accumulation of glucosylceramide in murine testis, caused by inhibition of beta-glucosidase 2: implications for spermatogenesis. (2007) (67)
- Design, Synthesis, and Biological Evaluation of Enantiomeric β‐N‐Acetylhexosaminidase Inhibitors LABNAc and DABNAc as Potential Agents against Tay‐Sachs and Sandhoff Disease (2009) (67)
- Identification of Specific Glycoforms of Major Histocompatibility Complex Class I Heavy Chains Suggests That Class I Peptide Loading Is an Adaptation of the Quality Control Pathway Involving Calreticulin and ERp57* (2002) (66)
- Glycosylation Influences the Lectin Activities of the Macrophage Mannose Receptor* (2005) (66)
- Pre-eclampsia is associated with an increase in trophoblast glycogen content and glycogen synthase activity, similar to that found in hydatidiform moles. (1993) (65)
- Changes of serum glycans during sepsis and acute pancreatitis. (2007) (65)
- Biological importance of glycosylation. (1998) (65)
- Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells (2010) (65)
- Analytical and preparative separation of anionic oligosaccharides by weak anion-exchange high-performance liquid chromatography on an inert polymer column. (1994) (64)
- Characterisation of oligosaccharides from Drosophila melanogaster glycoproteins. (1991) (63)
- Substrate reduction therapy in mouse models of the glycosphingolipidoses. (2003) (63)
- The glycosylphosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoprotein. (1988) (63)
- Site-specific glycosylation of recombinant rat and human soluble CD4 variants expressed in Chinese hamster ovary cells. (1993) (62)
- Diversification of the IgG molecule by oligosaccharides. (1991) (62)
- Small-molecule therapeutics for the treatment of glycolipid lysosomal storage disorders. (2003) (62)
- Principles and Problems in Physical Chemistry for Biochemists (1974) (61)
- Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases—Not Glycolipid Processing Enzymes (2016) (60)
- Two-domain structure of the native and reactive centre cleaved forms of C1 inhibitor of human complement by neutron scattering. (1990) (60)
- Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin† ‡ (2007) (60)
- Structures of the sugar chains of rabbit immunoglobulin G: occurrence of asparagine-linked sugar chains in Fab fragment. (1985) (60)
- The solution conformation of the Leχ group (1991) (59)
- High-performance liquid chromatography analysis of ganglioside carbohydrates at the picomole level after ceramide glycanase digestion and fluorescent labeling with 2-aminobenzamide. (2001) (58)
- The combination of interferon alpha-2b and n-butyl deoxynojirimycin has a greater than additive antiviral effect upon production of infectious bovine viral diarrhea virus (BVDV) in vitro: implications for hepatitis C virus (HCV) therapy. (2002) (58)
- Selective Deactivation of Serum IgG: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions (2012) (58)
- Effects of Interferon, Ribavirin, and Iminosugar Derivatives on Cells Persistently Infected with Noncytopathic Bovine Viral Diarrhea Virus (2004) (57)
- Tyrosinase and glycoprotein folding: roles of chaperones that recognize glycans. (2000) (57)
- Inhibition of hybrid- and complex-type glycosylation reveals the presence of the GlcNAc transferase I-independent fucosylation pathway. (2006) (57)
- Iminosugar antivirals: the therapeutic sweet spot (2017) (57)
- Glycan analysis of monoclonal antibodies secreted in deposition disorders indicates that subsets of plasma cells differentially process IgG glycans. (2006) (57)
- Characterisation of the asparagine-linked oligosaccharides from Trypanosoma brucei type-I variant surface glycoproteins. (1990) (56)
- Reduction of the infectivity of hepatitis C virus pseudoparticles by incorporation of misfolded glycoproteins induced by glucosidase inhibitors. (2007) (56)
- Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum. (2007) (55)
- N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery (2008) (55)
- Structures of the N-linked oligosaccharides of Gp63, the major surface glycoprotein, from Leishmania mexicana amazonensis. (1990) (54)
- Identification of highly fucosylated N-linked oligosaccharides from the human parotid gland. (1998) (54)
- Identification of Lectin‐Purified Neural Glycoproteins, GPs 180, 116, and 110, with NMDA and AMPA Receptor Subunits: Conservation of Glycosylation at the Synapse (1998) (53)
- Inhibition of Glucosylceramide Synthase Does Not Reverse Drug Resistance in Cancer Cells* (2004) (52)
- Chromophore structure in the photocycle of the cyanobacterial phytochrome Cph1. (2006) (52)
- Alkylated Imino Sugars, Reversible Male Infertility-Inducing Agents, Do Not Affect the Genetic Integrity of Male Mouse Germ Cells During Short-Term Treatment Despite Induction of Sperm Deformities1 (2005) (52)
- Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited. (1997) (51)
- Interaction of Clq with DNA (1982) (51)
- Applying proteomics technology to platelet research. (2005) (51)
- An n.m.r. study of keto–enol tautomerism in β-diketones (1966) (51)
- Targeted drug delivery (1986) (51)
- Remarkable selective glycosylation of the immunoglobulin variable region in follicular lymphoma. (2008) (51)
- Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody (2006) (50)
- Antiviral effect of alpha-glucosidase inhibitors on viral morphogenesis and binding properties of hepatitis C virus-like particles. (2006) (49)
- A Proteomic Approach for the Discovery of Early Detection Markers of Hepatocellular Carcinoma (2002) (49)
- Monitoring endoplasmic reticulum-to-Golgi traffic of a plant calreticulin by protein glycosylation analysis. (2002) (49)
- Major Histocompatibility Complex Class I Molecules Expressed with Monoglucosylated N-Linked Glycans Bind Calreticulin Independently of Their Assembly Status* (2004) (49)
- Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d (2010) (49)
- Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure (2004) (47)
- A transient rise in agalactosyl IgG correlating with free interleukin 2 receptors, during episodes of erythema nodosum leprosum. (1989) (47)
- Membrane disruption and cytotoxicity of hydrophobic N-alkylated imino sugars is independent of the inhibition of protein and lipid glycosylation. (2003) (47)
- Identification of phosphorylated 3-deoxy-manno-octulosonic acid as a component of Haemophilus influenzae lipopolysaccharide. (1987) (47)
- O-Glycan Sialylation and the Structure of the Stalk-like Region of the T Cell Co-receptor CD8* (2003) (47)
- COVID-19 therapeutics: Challenges and directions for the future (2022) (46)
- Binding of complement subcomponent C1q to mouse IgG1, IgG2a and IgG2b: a novel C1q binding assay. (1984) (45)
- Glycolipid depletion in antimicrobial therapy (2003) (44)
- The glycosylation of glycoprotein lectins. Intra- and inter-genus variation in N-linked oligosaccharide expression. (1991) (44)
- Making autoantibodies safe (2008) (44)
- Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody. (2007) (44)
- Nef-mediated lipid raft exclusion of UbcH7 inhibits Cbl activity in T cells to positively regulate signaling. (2005) (43)
- Looking glass inhibitors: L-DMDP, a more potent and specific inhibitor of alpha-glucosidases than the enantiomeric natural product DMDP. (2004) (43)
- Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type" neutral N-glycans. (1999) (43)
- Discovery of Novel Biomarker Candidates for Liver Fibrosis in Hepatitis C Patients: A Preliminary Study (2012) (43)
- The role of IgG glycoforms in the pathogenesis of rheumatoid arthritis (2005) (43)
- N-glycosylation processing and glycoprotein folding-lessons from the tyrosinase-related proteins. (2000) (43)
- Studies on the interaction of ligands with phosphorylase b using a spin-label probe. (1972) (43)
- Protein specific N-glycosylation of tyrosinase and tyrosinase-related protein-1 in B16 mouse melanoma cells. (1999) (42)
- Remnant epitopes, autoimmunity and glycosylation. (2006) (42)
- Cellular effects of deoxynojirimycin analogues: inhibition of N-linked oligosaccharide processing and generation of free glucosylated oligosaccharides. (2004) (42)
- Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4 (2016) (41)
- Oligosaccharide analysis and molecular modeling of soluble forms of glycoproteins belonging to the Ly-6, scavenger receptor, and immunoglobulin superfamilies expressed in Chinese hamster ovary cells. (1999) (41)
- Use of large-scale hydrazinolysis in the preparation ofN-linked oligosaccharide libraries: application to brain tissue (1992) (40)
- The lanthanide cations as nuclear magnetic resonance probes of biological systems (1970) (40)
- Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral Spike (2021) (40)
- Comparative analysis of the N-glycans of rat, mouse and human Thy-1. Site-specific oligosaccharide patterns of neural Thy-1, a member of the immunoglobulin superfamily. (1993) (40)
- The interaction of protein A and Fc fragment of rabbit immunoglobulin G as probed by complement-fixation and nuclear-magnetic-resonance studies. (1977) (39)
- Structural characterization of the N-glycan moiety and site of glycosylation in vitellogenin from the decapod crustacean Cherax quadricarinatus. (2004) (39)
- Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease. (2015) (39)
- Imino Sugars That are Less Toxic but More Potent as Antivirals, In Vitro, Compared with N-n-Nonyl DNJ (2002) (39)
- The Activation of Type 1 and Type 2 Plasminogen by Type I and Type II Tissue Plasminogen Activator (*) (1995) (39)
- Cellular effects of deoxynojirimycin analogues: uptake, retention and inhibition of glycosphingolipid biosynthesis. (2004) (39)
- Structural Studies on the Combining Site of the Myeloma Protein MOPC 315 (1975) (39)
- Synthetic glycosylation of proteins using N-(beta-saccharide) iodoacetamides: applications in site-specific glycosylation and solid-phase enzymic oligosaccharide synthesis. (1994) (39)
- Interaction of mannan binding lectin with alpha2 macroglobulin via exposed oligomannose glycans: a conserved feature of the thiol ester protein family? (2006) (39)
- Inhibition of host ER glucosidase activity prevents Golgi processing of virion-associated bovine viral diarrhea virus E2 glycoproteins and reduces infectivity of secreted virions. (2002) (38)
- Soluble Tyrosinase is an Endoplasmic Reticulum (ER)-associated Degradation Substrate Retained in the ER by Calreticulin and BiP/GRP78 and Not Calnexin* (2005) (38)
- Immunology. Sugar determines antibody activity. (2006) (38)
- Direct deprotected glycosyl-asparagine ligation. (2006) (38)
- Proteome analysis of a human uveal melanoma primary cell culture by 2‐DE and MS (2005) (38)
- The binding of lanthanides to non-immune rabbit immunoglobulin G and its fragments. (1975) (38)
- Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design. (2003) (38)
- A human T-cell receptor recognizes 'O'-linked sugars from the hinge region of human IgA1 and IgD. (1994) (37)
- Structural determination of the N-glycans of a lepidopteran arylphorin reveals the presence of a monoglucosylated oligosaccharide in the storage protein. (2003) (37)
- Identification of N-glycans from Ebola virus glycoproteins by matrix-assisted laser desorption/ionisation time-of-flight and negative ion electrospray tandem mass spectrometry. (2010) (37)
- The binding of monosaccharide inhibitors to hen egg-white lysozyme by proton magnetic resonance at 270 MHz and analysis by ring-current calculations. (1981) (37)
- Isomerization of deoxyhexoses: green bioproduction of 1-deoxy-d-tagatose from l-fucose and of 6-deoxy-d-tagatose from d-fucose using Enterobacter agglomerans strain 221e (2008) (36)
- Liposome-Mediated Delivery of Iminosugars Enhances Efficacy against Dengue Virus In Vivo (2012) (36)
- Fragmentation of negative ions from N-linked carbohydrates, part 4. Fragmentation of complex glycans lacking substitution on the 6-antenna. (2010) (36)
- A Human Embryonic Kidney 293T Cell Line Mutated at the Golgi α-Mannosidase II Locus* (2009) (35)
- Design and synthesis of iminosugar-based inhibitors of glucosylceramide synthase: the search for new therapeutic agents against Gaucher disease (2005) (35)
- The combining site of the dinitrophenyl-binding immunoglobulin A myeloma protein MOPC 315. (1977) (35)
- Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells. (2000) (35)
- The Inhibition of Early N-Glycan Processing Targets TRP-2 to Degradation in B16 Melanoma Cells* (2003) (35)
- Chemical and enzymatic N-glycan release comparison for N-glycan profiling of monoclonal antibodies expressed in plants. (2010) (35)
- Separation and analysis of the glycoform populations of ribonuclease B using capillary electrophoresis (1992) (34)
- Detection of Multisulphated N‐Linked Glycans in the L2/HNK‐1 Carbohydrate Epitope Expressing Neural Adhesion Molecule P0 (1992) (34)
- Glycosylation of interleukin-6 purified from normal human blood mononuclear cells. (1992) (34)
- O-Linked Glycosylation in Focus (2000) (32)
- Synthesis of and NMR studies on the four diastereomeric 1-deoxy-d-ketohexoses (2007) (32)
- Mutant analysis reveals an alternative pathway for N-linked glycosylation in Drosophila melanogaster. (1998) (32)
- The isolation by ligand affinity chromatography of a novel form of alpha-L-fucosidase from almond. (1990) (32)
- Structural analysis of the CD5 antigen--expression, disulphide bond analysis and physical characterisation of CD5 scavenger receptor superfamily domain 1. (1998) (32)
- Cholesterol Depletion of Hepatoma Cells Impairs Hepatitis B Virus Envelopment by Altering the Topology of the Large Envelope Protein (2011) (32)
- Rheumatoid arthritis as a glycosylation disorder. (1988) (32)
- Building blocks for solid-phase glycopeptide synthesis: 2-acetamido-2-deoxy-β-D-glycosides of FmocSerOH and FmocThrOH (1994) (31)
- Multiple-step relayed correlation spectroscopy: sequential resonance assignments in oligosaccharides. (1984) (31)
- Looking glass inhibitors: efficient synthesis and biological evaluation of D-deoxyfuconojirimycin. (2005) (30)
- Proton relaxation enhancement probes: Applications and limitations to systems containing macromolecules (1972) (30)
- Relationship between conformationally sensitive probe binding sites on phosphorylase b. (1971) (30)
- Nuclear electron double resonance and scalar interactions in solutions (1966) (30)
- Solution conformation of biantennary complex type oligosaccharides (1983) (30)
- Determining the Structure of Oligosaccharides N‐ and O‐Linked to Glycoproteins (2000) (30)
- pH-sensitive liposomes are efficient carriers for endoplasmic reticulum-targeted drugs in mouse melanoma cells. (2002) (30)
- The identification and characterization of xenoantigenic nonhuman carbohydrate sequences in membrane proteins from porcine kidney (2006) (30)
- N-glycosylation and the production of recombinant glycoproteins (1989) (30)
- The mechanism of water-proton relaxation in enzyme paramagnetic-ion complexes. 1. The Gd(3)-lysozyme complex. (1974) (30)
- Analytical strategies to investigate plant N-glycan profiles in the context of plant-made pharmaceuticals. (2006) (30)
- Solution conformation of the biantennary N‐linked oligosaccharide of human serotransferrin using 1H NMR nuclear Overhauser effect measurements (1982) (29)
- α-Galactosylceramide and Novel Synthetic Glycolipids Directly Induce the Innate Host Defense Pathway and Have Direct Activity against Hepatitis B and C Viruses (2004) (29)
- Proteomic analysis of HepaRG cells: a novel cell line that supports hepatitis B virus infection. (2009) (29)
- Suppression of allogeneic reactivity in vitro by the syncytiotrophoblast membrane glycocalyx of the human term placenta is carbohydrate dependent. (1994) (29)
- Modulation of THP-1 macrophage and cholesterol-loaded foam cell apolipoprotein E levels by glycosphingolipids. (2002) (29)
- Efficient synthesis from d-lyxonolactone of 2-acetamido-1,4-imino-1,2,4-trideoxy-l-arabinitol LABNAc, a potent pyrrolidine inhibitor of hexosaminidases (2007) (28)
- Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides. (2006) (28)
- Isolation synthesis and glycosidase inhibition profile of 3-epi-casuarine (2006) (28)
- Cytokine and protease glycosylation as a regulatory mechanism in inflammation and autoimmunity. (1998) (27)
- An Inducible Mouse Model of Late Onset Tay–Sachs Disease (2002) (27)
- Long-term non-hormonal male contraception in mice using N-butyldeoxynojirimycin. (2006) (27)
- Comparative glycosylation in neural adhesion molecules. (1992) (27)
- Structure-Activity Relationship of a New Class of Anti-Hepatitis B Virus Agents (2002) (27)
- Synthesis of 1-N-glycyl beta-oligosaccharide derivatives. Reactivity of Lens culinaris lectin with a fluorescent labeled streptavidin pseudoglycoprotein and immobilized neoglycolipid. (1992) (27)
- N‐butyldeoxynojirimycin causes weight loss as a result of appetite suppression in lean and obese mice (2007) (27)
- New therapeutics for the treatment of glycosphingolipid lysosomal storage diseases. (2003) (27)
- Abnormal glycosylation with hypersialylated O-glycans in patients with Sialuria. (2006) (26)
- Oligosaccharides of recombinant mouse gelatinase B variants. (1998) (26)
- Sialylation of urinary prothrombin fragment 1 is implicated as a contributory factor in the risk of calcium oxalate kidney stone formation (2006) (26)
- Spirodiketopiperazines of mannofuranose: carbopeptoid α-amino acid esters at the anomeric position of mannofuranose (1998) (26)
- The gross architecture of an antibody-combining site as determined by spin-label mapping. (1977) (26)
- Cancer-associated glycoforms of gelatinase B exhibit a decreased level of binding to galectin-3. (2006) (25)
- Oligosaccharides modulate the apoptotic activity of glycodelin. (2006) (25)
- Formation of complement subcomponent C1q-immunoglobulin G complex. Thermodynamic and chemical-modification studies. (1982) (25)
- A novel approach to water proton relaxation in paramagnetic ion-macromolecule complexes. (1977) (25)
- New Approaches for Biomarker Discovery: The Search for Liver Fibrosis Markers in Hepatitis C Patients (2011) (25)
- Changes in carbohydrate structure of IgG in rheumatoid arthritis. (1988) (25)
- Synthesis of 2-C-branched derivatives of d-mannose: 2-C-aminomethyl-d-mannose binds to the human C-type lectin DC-SIGN with affinity greater than an order of magnitude compared to that of d-mannose (2007) (25)
- Inhibition of glycogen breakdown by imino sugars in vitro and in vivo. (2004) (24)
- Sugar amino acids at the anomeric position of carbohydrates : synthesis of spirocyclic amino acids of 6-deoxy-L-lyxofuranose (2006) (24)
- Uncertainties in structural determinations of oligosaccharide conformation, using measurements of nuclear Overhauser effects. (1990) (24)
- Identification and removal of O-linked and non-covalently linked sugars from recombinant protein produced using Pichia pastoris. (2004) (24)
- The pestivirus E(rns) glycoprotein interacts with E2 in both infected cells and mature virions. (2003) (24)
- Glycoproteins: rapid sequencing technology for N-linked and GPI anchor glycans. (1999) (24)
- Abnormal cell cycle regulation in primary human uveal melanoma cultures (2004) (24)
- Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids (2015) (23)
- A galactopyranose analogue of hydantocidin (1996) (23)
- The carbohydrate moiety of serum IgM from Atlantic cod (Gadus morhua L.). (2002) (23)
- The identification of abnormal glycoforms of serum transferrin in carbohydrate deficient glycoprotein syndrome type i by capillary zone electrophoresis (1996) (23)
- Neutron scattering studies of subcomponent C1q of first component C1 of human complement and its association with subunit C1r2C1s2 within C1. (1984) (23)
- Monosialylated biantennary N-glycoforms containing GalNAc-GlcNAc antennae predominate when human EPO is expressed in goat milk. (2008) (23)
- The beta 1----2-D-xylose and alpha 1----3-L-fucose substituted N-linked oligosaccharides from Erythrina cristagalli lectin. Isolation, characterisation and comparison with other legume lectins. (1987) (23)
- Primary sequence dependence of conformation in oligomannose oligosaccharides (2006) (23)
- The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein (2011) (22)
- Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins (2013) (22)
- Comparison of the N-linked glycans from soluble and GPI-anchored CD59 expressed in CHO cells. (2002) (22)
- Dynamic polarization of protons and fluorine nuclei in solutions of free radicals (1967) (22)
- Tyrosinase-related protein-2 and -1 are trafficked on distinct routes in B16 melanoma cells. (2005) (22)
- Towards the biotechnological isomerization of branched sugars: d-tagatose-3-epimerase equilibrates both enantiomers of 4-C-methyl-ribulose with both enantiomers of 4-C-methyl-xylulose (2008) (22)
- Dropping anchor with the lipophosphoglycans (1991) (21)
- Molecular characterization of Limulus polyphemus C-reactive protein. II. Asparagine-linked oligosaccharides. (1993) (21)
- Improved cellular inhibitors for glycoprotein processing α-glucosidases: biological characterisation of alkyl- and arylalkyl-N-substituted deoxynojirimycins (2009) (21)
- Human immunoglobulin glycosylation and the lectin pathway of complement activation. (2005) (21)
- Antibody--hapten interactions in solution. (1975) (21)
- Plant N-glycan profiling of minute amounts of material. (2008) (21)
- Comparison of the fine specificity of anti-dinitrophenyl-combining site composed of either VL dimer or VL and VH of protein 315. (1977) (21)
- Long alkylchain iminosugars block the HCV p7 ion channel. (2005) (21)
- δ-Lactams: synthesis from D-glucose, and preliminiary evaluation as a fucosidase inhibitor, of L-fuconic-δ-lactam (1988) (21)
- Proteomics in uveal melanoma research: opportunities and challenges in biomarker discovery (2007) (21)
- The glycan processing and site occupancy of recombinant Thy-1 is markedly affected by the presence of a glycosylphosphatidylinositol anchor. (1999) (20)
- Spin-labelled phosphofructokinase and its interactions with ATP and metal-ATP complexes as studied by magnetic-resonance methods. (1973) (20)
- Green syntheses of new 2-C-methyl aldohexoses and 5-C-methyl ketohexoses: d-tagatose-3-epimerase (DTE)—a promiscuous enzyme (2008) (20)
- Probes for the Conformational Transitions of Phosphorylase a (1972) (20)
- Targeting ER α-glucosidase I with a single-dose iminosugar treatment protects against lethal influenza and dengue virus infections. (2020) (20)
- Some recent applications of the use of paramagnetic centres to probe biological systems using nuclear magnetic resonance (1977) (20)
- Determining the Structure of Glycan Moieties by Mass Spectrometry (2000) (20)
- Role of N-glycan trimming in the folding and secretion of the pestivirus protein E(rns). (2004) (20)
- Hepatitis B Virus Large and Middle Glycoproteins Are Degraded by a Proteasome Pathway in Glucosidase-Inhibited Cells but Not in Cells with Functional Glucosidase Enzyme (2005) (20)
- Brefeldin A inhibits pestivirus release from infected cells, without affecting its assembly and infectivity. (2006) (20)
- Synthesis of 1,5-dideoxy-3-O-(α-D-mannopyranosyl)-1,5-imino-D-mannitol and 1,5-dideoxy-3-O-(α-D-glucopyranosyl)-1,5-imino-D-mannitol: Powerful inhibitors of endomannosidase (1993) (20)
- One-Dimensional Inverse-Detected Methods for Measurement of Long-Range Proton-Carbon Coupling Constants. Application to Saccharides (1994) (19)
- N-glycosylation pattern of E2 glycoprotein from classical swine fever virus. (2009) (19)
- The glycosylation of Bowes melanoma tissue plasminogen activator: lectin mapping, reaction with anti-L2/HNK-1 antibodies and the presence of sulphated/glucuronic acid containing glycans. (1996) (19)
- Iminosugars in Combination with Interferon and Ribavirin Permanently Eradicate Noncytopathic Bovine Viral Diarrhea Virus from Persistently Infected Cells (2008) (19)
- A structural study by 19 F-nuclear-magnetic resonance of the binding of sugars to lysozyme. (1972) (19)
- The conformational properties of the Glc3Man unit suggest conformational biasing within the chaperone-assisted glycoprotein folding pathway. (2009) (18)
- Carbopeptoids: peptides and diketopiperazines incorporating the anomeric centre of mannopyranose (2001) (18)
- Abnormalities in the glycosylation of IgG in spouses of patients with rheumatoid arthritis. A family study. (1991) (18)
- Cell surface oligosaccharides on Dictyostelium during development (1991) (18)
- Proton-electron double resonance in organic compounds (1967) (18)
- Structural and conformational analysis of immunoglobulin-derived N-linked oligosaccharides. (1983) (18)
- Role of disulfide bond formation in the folding and assembly of the envelope glycoproteins of a pestivirus (2002) (18)
- Piperidine analogues of D-galactose as potent inhibitors of α-galactosidase: Synthesis by stannane-mediated hydroxymethylation of 5-azido-1,4-lactones. Structural relationships between D-galactosidase and L-rhamnosidase inhibitors (1999) (18)
- Difficulties in determining accurate molecular motion parameters from proton relaxation enhancement measurements as illustrated by the immunoglobulin G-Gd(III) system. (1976) (18)
- The proton relaxation of methyl cyanide in the presence of Ni(II) ions, as studied by spin-echo techniques (1971) (17)
- The conformation of subcomponent C1q of the first component of human complement (1980) (17)
- Magnetic resonance studies on manganese-activated phosphofructokinase. (1972) (17)
- Inhibition of α-Glucosidases I and II Increases the Cell Surface Expression of Functional Class A Macrophage Scavenger Receptor (SR-A) by Extending Its Half-life* (2004) (17)
- Demonstration that endoplasmic reticulum-associated degradation of glycoproteins can occur downstream of processing by endomannosidase. (2011) (17)
- Syncytiotrophoblast membrane protein glycosylation patterns in normal human pregnancy and changes with gestational age and parturition (1991) (17)
- 9-Fluorenylmethoxycarbonyl (Fmoc)-glycine coupling of saccharide beta-glycosylamines for the fractionation of oligosaccharides and the formation of neoglycoconjugates. (1994) (17)
- Conformational changes in glycogen phosphorylase studied with a spin-label probe. (1976) (17)
- Antiviral effect of a-glucosidase inhibitors on viral morphogenesis and binding properties of hepatitis C virus-like particles (2006) (17)
- The dependence of the fluorine-electron Overhauser effect upon the correlation time of the molecular motion in liquids (1966) (16)
- Full simulation of ROESY, including the Hartmann-Hahn effects (1990) (16)
- Spirodiketopiperazines at the anomeric position of mannopyranose: Novel N- linked glycopeptides incorporating an α- amino acid at the anomeric position of mannopyranose (1995) (16)
- Heterotropic interactions of ligands with phosphorylase b. (1976) (16)
- Glycosylation of CD4 and Thy-1. (1993) (16)
- Interactions of the lanthanide- and hapten-binding sites in the Fv fragment from the myeloma protein MOPC 315. (1976) (16)
- Dynamic polarization of photophosphorus-31 nuclei. Some effects of chemical environment (1969) (16)
- High-performance cation-exchange chromatography and pulsed amperometric detection for the separation, detection, and quantitation of N-alkylated imino sugars in biological samples. (2000) (16)
- Spin labelling methods in molecular biology: By G. I. Likhtenstein. (Translated from the Russian by P. S. Shelnitz.) Pp 258. John Wiley and Sons Ltd. £26.00 or $39.00 (1977) (16)
- The Thy-1 glycoprotein: a three-dimensional model. (1988) (16)
- HPLC Strategies for Profiling and Sequencing Oligosaccharides (1997) (16)
- Configurational dependencies of 19F-shifts in fluoromonosaccharides (1971) (15)
- Carbohydrate receptor depletion as an antimicrobial strategy for prevention of urinary tract infection. (2001) (15)
- Glycolipid precursors for the membrane anchor of Trypanosoma brucei variant surface glycoproteins. I. Can structure of the phosphatidylinositol-specific phospholipase C sensitive and resistant glycolipids. (1990) (15)
- Interaction of C1q with DNA. (1982) (15)
- The 220 MHz proton magnetic resonance spectra of derivatives of 5-deoxy-5-iodo-α-d-xylo-pentofuranose (1970) (15)
- Neutron scattering studies of the isolated C1r2C1s2 subunit of first component of human complement in solution. (1983) (15)
- Disruption of α‐mannosidase processing induces non‐canonical hybrid‐type glycosylation (2007) (15)
- Hepatitis B virus MHBs antigen is selectively sensitive to glucosidase-mediated processing in the endoplasmic reticulum. (2001) (15)
- The binding of 2,4,6-trinitrophenyl derivatives to the mouse myeloma immunoglobulin A protein MOPC 315. (1978) (15)
- Agalactosyl IgG, antibodies to heat shock proteins, and acute rheumatic fever. (1990) (15)
- A method for the rapid assignment of 1H NMR spectra of oligosaccharides using homonuclear Hartmann-Hahn spectroscopy. (1987) (14)
- Analysis of SARS-CoV-2 spike glycosylation reveals shedding of a vaccine candidate (2020) (14)
- New methods for measurement of long-range proton-carbon coupling constants in oligosaccharides (1992) (13)
- Lysosomal storage of oligosaccharide and glycosphingolipid in imino sugar treated cells (2010) (13)
- The determination of molecular-motion parameters from proton-relaxation-enhancement measurements in a number of Gd(III) - antibody-fragment complexes. A comparative study. (1977) (13)
- A family of novel, acidic N-glycans in Bowes melanoma tissue plasminogen activator have L2/HNK-1-bearing antennae, many with sulfation of the fucosylated chitobiose core. (2001) (13)
- Glycosylation and the Complement System (2002) (13)
- Glycosylation and the immune system. (1999) (13)
- Fluorocarbohydrates : Part XIX. The molecular structure of 3,4,6-tri-O-acetyl-2-bromo-2-deoxy-α-d-mannopyranosyl fluoride and related compounds (1969) (13)
- Does rapid oligomerization of hepatitis B envelope proteins play a role in resistance to proteasome degradation and enhance chronicity? (2006) (13)
- Dynamic Polarization of 31P Nuclei: Some Evidence for Stereospecific Hyperfine Interactions in Liquids (1969) (13)
- The analysis of coupling networks in a complex oligosaccharide mixture derived from the Fc region of rabbit immunoglobulin G using 1H-1H correlated NMR spectroscopy combined with double quantum NMR spectroscopy. (1984) (13)
- Synovial stimulatory protein fragments copurify with woodchuck hepatitis virus: implications for the etiology of arthritis in chronic hepatitis B virus infection. (2001) (13)
- Mobility and symmetry in the Fc and pFc' fragments as probed by 1H NMR. (1979) (13)
- Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing (2007) (13)
- Scalar interactions in phosphorus-31 systems as studied by dynamic nuclear polarization (1967) (13)
- The goat mammary glandular epithelial (GMGE) cell line promotes polyfucosylation and N,N'-diacetyllactosediaminylation of N-glycans linked to recombinant human erythropoietin. (2007) (13)
- Synthesis of major histocompatibility complex class I binding glycopeptides (1995) (13)
- Analysis of carbohydrate-protein interactions with synthetic N-linked neoglycoconjugate probes. (1993) (12)
- The role of nitro groups in the binding of nitroaromatics to protein MOPC 315. (1978) (12)
- GALACTOSYLATION OF IgG ASSOCIATED OLIGOSACCHARIDES (1988) (12)
- Glycosylation: disease targets and therapy. (2005) (12)
- Role of glycan processing in hepatitis B virus envelope protein trafficking. (1998) (12)
- The role of oligosaccharides in modifying protein function. (1989) (12)
- New developments in treating glycosphingolipid storage diseases. (2005) (12)
- Structure-function relationships in immunoglobulins. (1984) (12)
- Detailed N-glycan analysis of mannose receptor purified from murine spleen indicates tissue specific sialylation. (2009) (12)
- High-throughput screening of glycan-binding proteins using miniature pig kidney N-glycan-immobilized beads. (2008) (12)
- Commercialising University Research: Threats and Opportunities--The Oxford Model (2008) (12)
- The use of two-dimensional correlated spectroscopy to obtain new assignments in the high-resolution 1H nuclear magnetic resonance spectrum of the biantennary complex oligosaccharide isolated from human serum transferrin by hydrazinolysis. (1983) (12)
- Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesis. (2005) (12)
- Application of ring-current theory based on the Johnson-Bovey equation to the aromatic amino acids. (1977) (11)
- Comparison of the dimensions of the combining sites of the dinitrophenyl-binding immunoglobulin A myeloma proteins MOPC 315, MOPC 460 and XRPC 25 by spin-label mapping. (1977) (11)
- Fast sequencing of oligosaccharides using arrays of enzymes (1992) (11)
- Nuclear magnetic resonance of aqueous solutions of sodium perrhenate (1970) (11)
- Artefacts formed by addition of urea to N-linked glycans released with peptide-N-glycosidase F for analysis by mass spectrometry. (2004) (11)
- The role of N-linked glycosylation in the secretion of hepatitis B virus. (1998) (11)
- Structural basis of recognition in the immune response. (1978) (11)
- A strategy for anti-viral intervention: the use of alpha-glucosidase inhibitors to prevent chaperone-mediated folding of viral envelope glycoproteins. (1997) (11)
- The simultaneous binding of lanthanide and N-acetylglucosamine inhibitors to hen egg-white lysozyme in solution by 1H and 13C nuclear magnetic resonance. (1981) (11)
- Productive Folding of Tyrosinase Ectodomain Is Controlled by the Transmembrane Anchor* (2006) (11)
- Proton relaxation studies of dimethyl sulphoxide in dilute solutions of nickel (II) ions (1968) (11)
- The use of gadolinium as a probe in the Fc region of a homogeneous anti-(type-III pneumococcal polysaccharide) antibody. (1977) (11)
- Fluorine chemical shifts in some monosaccharide derivatives. (1970) (10)
- A theory for the intermolecular nucleus-electron scalar interaction and its application to dynamic polarisation results of phosphorus-31 nuclei (1970) (10)
- Spin label and lanthanide binding sites on glyceraldehyde-3-phosphate dehydrogenase. (1975) (10)
- Specificity of interactions of hapten side chains with the combining site of the myeloma protein MOPC 315. (1977) (10)
- Crystallization of the Fv fragment of mouse myeloma protein M315. (1979) (10)
- Effect of SerineO-Glycosylation onCis-TransProline Isomerization (1996) (10)
- Imino sugar therapy for type 1 Gaucher disease. (2000) (10)
- Investigation of the intracellular transport of tyrosinase and tyrosinase related protein (TRP)-1. The effect of endoplasmic reticulum (ER)-glucosidases inhibition. (1999) (10)
- Identification of high-mannose and multiantennary complex-type N-linked glycans containing α-galactose epitopes from Nurse shark IgM heavy chain (2009) (10)
- The mechanism of water-proton relaxation in enzyme-paramagnetic-ion complexes. 2. The Mn(II)-ATP-phosphofructokinase ternary complex. (1974) (10)
- Interaction of saccharide haptens with myeloma proteins. A 270-MHz proton nuclear magnetic resonance study. (1981) (10)
- The N-glycosylation of classical swine fever virus E2 glycoprotein extracellular domain expressed in the milk of goat. (2010) (9)
- Lectin-carbohydrate interactions in disease. T-cell recognition of IgA and IgD; mannose binding protein recognition of IgG0. (1995) (9)
- Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution. (2006) (9)
- Potent SARS-CoV-2 neutralizing antibodies selected from a human antibody library constructed decades ago (2020) (9)
- Toward a carbohydrate-based HIV-1 vaccine (2006) (9)
- The Role of Antigen in Autoimmune Responses with Special Reference to Changes in Carbohydrate Structure of IgG in Rheumatoid Arthritis (1989) (9)
- Strategies for spectral assignment in the 1H NMR spectra of a 25 000 M r murine antibody fragment: (i) in vivo deuteration and (ii) use of a denaturant (1981) (9)
- Role of tyrosines in the combining site of the dinitrophenyl-binding IgA myeloma M315: specific nitration and high-resolution hydrogen-1 nuclear magnetic resonance studies. (1982) (9)
- Neutralizing Antibodies to SARS‐CoV‐2 Selected from a Human Antibody Library Constructed Decades Ago (2021) (8)
- Glycosylation and the function of the T cell co-receptor CD8. (2005) (8)
- Extracting subspectra from overlapping regions. DOUBLE TOCSY (1990) (8)
- Disruption of alpha-mannosidase processing induces non-canonical hybrid-type glycosylation. (2007) (8)
- Review article: HCV ? STAT-C era of therapy (2010) (8)
- Phosphorus-31 nuclear magnetic resonance probes for the combining site of the myeloma protein M315. (1979) (8)
- Study of molecular motion in liquids by measurement of nuclear relaxation (1967) (8)
- Lectin-Carbohydrate Interactions in Disease (1995) (8)
- A combined proton and phosphorus-31 nuclear magnetic resonance investigation of the combining site of M603, a phosphocholine-binding myeloma protein. (1982) (8)
- Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model (2016) (7)
- Phosphorus-31 nuclear electron Overhauser studies of phosphorus chalcogenides (1969) (7)
- Spin-labelled phosphofructokinase. A simple and direct approach to the study of allosteric equilibria under near-physiological conditions. (1975) (7)
- The importance of including local correlation times in the calculation of inter-proton distances from NMR measurements: ignoring local correlation times leads to significant errors in the conformational analysis of the Glc alpha1-2Glc alpha linkage by NMR spectroscopy. (2006) (7)
- The glycosylation of the complement regulatory protein, human erythrocyte CD59. (1997) (7)
- N-fluoroacetyl-alpha-D-glucosamine as a molecular probe of lysozyme structure by using ( 19 F) fluorine nuclear-magnetic-resonance techniques. (1971) (7)
- Positive enhancement of proton resonances by dynamic nuclear polarization (1966) (7)
- The isolation of a globular fragment of rabbit immunoglobulin G probably corresponding to the intact C gamma 2 homology region. (1979) (7)
- Dynamic nuclear polarization in phosphonitrilic ring compounds (1969) (7)
- Glycoprotein glycosylation and the immunosuppressive effects of human pregnancy serum. (1992) (6)
- Identifying protein production in wound healing: current techniques. (2002) (6)
- Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry of N-Linked Carbohydrates and Related Compounds (2000) (6)
- Small-angle neutron scattering studies of the conformation of myeloma protein MOPC315 and its Fab fragment, and the interaction with a monovalent dinitrophenyl hapten (1981) (6)
- On the contribution of tryptophan to the affinity and specificity of anti-dinitrophenyl antibodies. (1981) (6)
- Characterisation of tissue-specific oligosaccharides from rat brain and kidney membrane preparations enriched in Na+,K+-ATPase (1999) (6)
- Accumulation of Glucosylceramide in Murine Testis, Caused by Inhibition of β-Glucosidase 2 (2007) (6)
- Protein-Protein Interactions : Modeling the Hepatitis C Virus Ion Channel p 7 (6)
- Enantiomeric 2-acetamido-1,4-dideoxy-1,4-iminoribitols as potential pyrrolidine hexosaminidase inhibitors (2011) (5)
- Journeys in science: glycobiology and other paths. (2014) (5)
- Structural glycobiology in medicine: Carbohydrates and glycoconjugates (2006) (5)
- Nitrogen relaxation of methyl cyanide in the presence of Ni(II) ions (1971) (5)
- Investigation of hapten—antibody interactions in McPC603 by 1H and 31P NMR spectroscopy (1977) (5)
- Antibody specificity: a 270-MHz hydrogen-1 nuclear magnetic resonance study of the binding of dinitrophenyl compounds to the VL dimer of protein 315. (1981) (5)
- Interaction of Mannan Binding Lectin with α2 Macroglobulin via Exposed Oligomannose Glycans (2006) (5)
- Relaxation theory: I. Variation of N.M.R. line-widths in AB systems (1967) (5)
- Emerging Principles for the Therapeutic Exploitation of (2016) (5)
- Pathogen‐induced inflammation is attenuated by the iminosugar MON‐DNJ via modulation of the unfolded protein response (2021) (5)
- The use of protein A and concanavalin A to examine the possible role of the carbohydrate of IgG in the binding of Clq. (1981) (5)
- Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design. (2005) (4)
- Directing stem cell differentiation with antibodies (2013) (4)
- Synthetic glycosylation of peptides using unprotected saccharide β-glycosylamines (1993) (4)
- Structural studies in solution on the combining site of the myeloma protein MOPC 315. (1977) (4)
- Glycosylation influences the ligand binding activities of mannose receptor. (2005) (4)
- Selective Inverse Correlation by Using Chemical-Shift-Selective Filters and Selective Pulses (1993) (4)
- Determining the Structure of Oligosaccharides N‐ and O‐Linked to Glycoproteins (2000) (4)
- Roles for glycosylation in the anti-inflammatory molecule CD59. (1997) (4)
- Specific spin labeling of the Fc region of immunoglobulins. FEBS Lett. 80, 133 (1977) (4)
- Can P-glycoprotein influence the bioavailability of iminosugar-based glucosylceramide synthase inhibitors? (2006) (4)
- 1,2:3,4-Di- O -isopropylidene-- D -psicofuranose (2005) (4)
- Structural and conformational analysis of immunoglobulin-derived N-linked oligosaccharides. (1983) (4)
- The preparation and properties of pyruvate kinase from yeast. (1974) (4)
- AN ANTIBODY BINDING SITE: A COMBINED MAGNETIC RESONANCE AND CRYSTALLOGRAPHIC APPROACH (1979) (4)
- The glycosylation of tyrosinase in melanoma cells and the effect on antigen presentation. (2003) (3)
- The variability of nitro group--protein interaction in the 2,4-dinitrophenyl-binding antibodies M315, M460 and X25 investigated by resonance Raman spectroscopy. (1981) (3)
- Comparison by1H NMR of the hapten environment in the combining site of the dinitrophenyl binding IgA protein 315 and its fragments (1978) (3)
- Proton-relaxation-enhancement studies on the binding to yeast pyruvate kinase of a substrate and effectors. (1972) (3)
- Physicochemical Studies on Regulatory Enzymes (1973) (3)
- Role of Nonbonded Interactions in Determining Solution Conformations of Oligosaccharides (1994) (3)
- THE STRUCTURE OF AN ANTIBODY COMBINING SITE (1978) (3)
- On Boiling an Egg (1972) (3)
- On the role of Tyr 34L in the antibody combining site of the dinitrophenyl binding protein 315. (1979) (3)
- Structural Studies on the Glycophospholipid Membrane Anchor of Trypanosoma Brucei Variant Surface Glycoprotein (1987) (2)
- Fluorocarbohydrates : Part XXII. 3-Deoxy-3-fluoro-D-gluconic acid (1972) (2)
- Conformational Studies of Oligosaccharides and Glycopeptides: Complementary of NMR, X-Ray Crystallography, and Molecular Modelling (2002) (2)
- Host-targeting oral antiviral drugs to prevent pandemics (2022) (2)
- Looking glass inhibitors: l-DMDP, a more potent and specific inhibitor of ?-glucosidases than the enantiomeric natural product DMDPThis work has been generously supported jointly by the Royal Society of London and the Chinese Academy of Sciences.Electronic supplementary information (ESI) available: (2004) (2)
- 1,2:3,4‐Di‐O‐isopropylidene‐α‐d‐tagatofuranose (2005) (2)
- Oxygen-17 nuclear magnetic resonance and oxygen exchange in aqueous solutions of iodate (1971) (2)
- N.m.r. investigation of hapten binding to the myeloma protein M460 (1980) (2)
- Comment on the article by Tomana et al. (1989) (2)
- Looking Glass Inhibitors: L‐DMDP, a More Potent and Specific Inhibitor of α‐Glucosidases than the Enantiomeric Natural Product DMDP. (2005) (2)
- Lanthanide Ions as Probes in Antibodies (1978) (2)
- GALACTOSE RESIDUES IN CHRONIC INFLAMMATORY DISEASE (1988) (2)
- Probe Studies on the Role of Protein-Protein Interactions and Enzyme Conformation in Control (1972) (2)
- Antibodies and antigens: It's all about the numbers game (2009) (2)
- Chapter 7 - Glycobiology: a Quantum Leap in Carbohydrate Chemistry (1996) (2)
- Chemical applications of magnetic resonance (1966) (2)
- Effect of serine O-glycosylation on cis-trans proline isomerization. (1996) (2)
- The significance of changes in IgG carbohydrate in rheumatoid arthritis and tuberculosis (1990) (2)
- Dynamic nuclear polarization in phosphorus compounds at 74 gauss (1969) (2)
- Phosphorylated prodrugs as glycosidase inhibitors (1990) (1)
- Holistic approaches to glycobiology (2001) (1)
- GALACTOSE RESIDUES IN CHRONIC INFLAMMATORY DISEASE - REPLY (1988) (1)
- Enzyme conformation and control. (1973) (1)
- Carbohydrates and glycoconjugates. (1995) (1)
- Iminosugars and methods of treatment of viral diseases (2010) (1)
- Structure Function Studies on Leishmania Surface Membrane Proteins (1989) (1)
- Probes for the conformational transitions of phosphorylase . Effect of ligands studied by proton-relaxation enhancement, and chemical reactivities. (1972) (1)
- Dynamic polarisation of phosphorus-31 nuclei at 12,500 gauss (1966) (1)
- THE HEPATITIS C VIRUS E2p7 LOCALIZATION AND TOPOLOGY IN A RECOMBINANT SYSTEM (2009) (1)
- Differential glycosylation of gelatinase B from neutrophils and breast cancer cells. (2005) (1)
- Glycoproteomics: High-Throughput Sequencing of Oligosaccharide Modifications to Proteins (2001) (1)
- ROLES FOR GLYCOSYLATION IN RECEPTOR- LIGAND INTERACTIONS IN THE IMMUNE SYSTEM (2005) (1)
- Targeting the host ER alpha glucosidases I and II as antiviral therapy (2007) (1)
- Oxford University's first spin-off company: Oxford GlycoSystems (2008) (1)
- Supporting Information for Practical Review DOI 10.1002/pmic.200700640 (2007) (1)
- P.161 Alpha-glucosidase inhibitors prevent the assembly and induce a reduction of HCV infectivity (2006) (1)
- N-alkyl deoxynojirimycins as antiviral compounds. (2002) (1)
- Studies on the Molecular Aspects of Phosphorylase b → a Conversion (1974) (1)
- The solution conformation of the Le chi group. (1991) (1)
- Structural studies on bromoglycosyl fluorides (1968) (1)
- Glycobiology at Oxford: A personal view (2006) (1)
- A novel method for mapping antibody combining sites by 1H nuclear magnetic resonance spectroscopy (1979) (1)
- substrate deprivation therapy and bone marrow transplantation Enhanced survival in Sandhoff disease mice receiving a combination of (2013) (1)
- Correction for Muindi et al., Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphinogolipids presented by CD1d (2010) (1)
- Direct Deprotected Glycosyl—Asparagine Ligation. (2006) (1)
- Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients using proteomics (2014) (1)
- Glucosidase inhibitors induce HCV glycoproteins misfolding, impair viral assembly and release, and reduce the infectivity of residually secreted HCV particles (2006) (1)
- Analysis of N‐ and O‐linked glycans of glycoproteins (2005) (1)
- Configurational dependencies of (19F) fluorine chemical shifts and coupling constants in fluoromonosaccharides. (1971) (1)
- Using n-butyl-deoxynojirimycin for the treatment of herpes. (1989) (0)
- The diagnostic method for the detection of rheumatoid arthritis or osteoarthritis (1986) (0)
- Use of n-alkyl derivatives of deoxynojirimycin long chain for the manufacture of a medicament for the treatment of diseases glycolipid storage. (1999) (0)
- The Localization of Effector Sites on Immunoglobulin G (1983) (0)
- Use of n-alkyl derivatives of 1,5-dideoxy-1,5-imino-d-glucitol for the treatment of infections Hepatitis B Virus. (1994) (0)
- MHC Class I binding glycopeptides (1995) (0)
- Pharmacological impairment of acrosome formation and sperm head morphogenesis reveals essential role of glycosphingolipids in spermiogenesis (2002) (0)
- A Galactopyranose Analogue of Hydantocidin. (2010) (0)
- A specific glycoform of MHC1 is required for the formation of the multimolecular complex involved in the assembly of the MHC1:peptide complexes (2002) (0)
- STUDIES ON THE MECHANISM OF ACTION OF N-BUTYL-DEOXYNOJIRIMYCIN AS AN INHIBITOR OF HIV REPLICATION (1995) (0)
- ANALYSIS OF GL YCOPROTEIN-ASSOC IATED OLIGOSACCHARIDES (1993) (0)
- Correction to N-Glycosylation Processing and Glycoprotein Folding-Lessons from the Tyrosinase-Related Proteins. (2020) (0)
- Synthesis of an IgA1 hinge region glycopeptide (1995) (0)
- P05-11. Yeast mannan genetics controls the molecular specificity of anti-carbohydrate antibodies cross-reactive to the HIV envelope (2009) (0)
- OP15 Discovery of new liver fibrosis markers in hepatitis C patients using proteomics (2011) (0)
- Exploring Functions for Glycosylation in Host Defence using Novel Oligosaccharide Sequencing Technology (2000) (0)
- 2-Acetamido-N-benzyl-1,4-imino-1,2,4-trideoxy-l-ribitol (2005) (0)
- Use of the 5- and 6-membered heterocyclic compounds for the manufacture of a composition for the treatment of patients infected with HIV (1988) (0)
- In: M. Fukada and Ole Hindsgaul, Editors, , Oxford University Press (1994) ISBN 0 19 963386 X, p. xiii. (1995) (0)
- Deoxynojirimycin analogues and D-arabinitol and methods of use (2007) (0)
- Decay accelerating factor (CD55): the structure of an intact human complement regulator. (2004) (0)
- Introduction to the spectroscopy of biological polymers: Edited by D. W. Jones, Pp. 328. Academic Press, London, New York and San Francisco. 1977. £11.60 or $25.50 (1977) (0)
- Process for the preparation of an anti-viral compound (1988) (0)
- Iminoazúcares for use in the treatment of bunyavirus and togavirus diseases (2010) (0)
- 1,2:3,4-Di-O-isopropylidene-a-D-tagatofuranose (2005) (0)
- Use of long chain N-alkyl derivatives of deoxynojirimycin for the manufacture of a medicament for the treatment of accumulation with glycolipids related diseases (1999) (0)
- Inhibitors of alpha glucosidases impair HCV pseudoparticles morphogenesis, prevent viral secretion and entry into hepatoma cells (2005) (0)
- Patent Number : 5 , 103 , 008 ( 45 ) Date of Patent : Apr . 7 , 1992 (2017) (0)
- An MRI technique for the quantification of atherosclerotic lesions in the ApoE knockout mouse (2002) (0)
- Pathogen-induced inflammation is attenuated by the iminosugar MON-DNJ via modulation of the unfolded protein response (2021) (0)
- Glycobiology – discovery, diagnosticsand drugs (2007) (0)
- S3.4 Preliminary studies on the structure of the putative second messenger of insulin (1993) (0)
- Erratum to “Design and synthesis of iminosugar-based inhibitors of glucosylceramide synthase: the search for new therapeutic agents against Gaucher disease”: [Tetrahedron: Asymmetry 16 (2005) 1747] (2005) (0)
- Iminosugars in combination with interferon and ribavirin permanently eradicate non-cytopathic bovine viral diarrhoea virus from persistently infected cells Running title: Iminosugars, IFN, and ribavirin clear BVDV infection (2008) (0)
- Glycolipids in cell biology and medicine - Introduction (2003) (0)
- A method for the treatment of CNS-diseases involving lysosomal storage (1998) (0)
- FAB 2G12 unliganded (2003) (0)
- Neutron scattering studies of the isolated Clr 2 Cis 2 sutbunit of first component of human complement in solution ( glycoproteins / ultracentrifugation ) (0)
- 2‐Acetamido‐N‐benzyl‐1,4‐imino‐1,2,4‐trideoxy‐l‐arabinitol 0.33‐hydrate (2005) (0)
- Contemporary Topics in Molecular Immunology (1977) (0)
- Using 1,5-dideoxy-1,5-imino-d-glucitol n-alkyl derivatives for the treatment of hepatitis B infections (1994) (0)
- Liberation ciblee de medicaments (2002) (0)
- Immunogenicity of calreticulin-bound murine leukemia virus glycoprotein gp90. (2005) (0)
- Piperidine Analogues of D-Galactose as Potent Inhibitors of α-Galactosidase: Synthesis by Stannane-Mediated Hydroxymethylation of 5-Azido-1,4-lactones. Structural Relationships Between D-Galactosidase and L-Rhamnosidase Inhibitors. (2010) (0)
- Misfolded middle surface antigen of hepatitis B virus, accumulating in glucosidase inhibited cells, inhibits new rounds of viral morphogenesis (2003) (0)
- Structural and Functional Studies of Serum Amyloid P Component (1991) (0)
- The use of long chain N-alkyl derivatives of deoxynojirimycin for the manufacture of a medicament for the treatment of diseases glycolipidophobnings (1999) (0)
- Prodrugs phosphorylated glycosidase inhibitors. (1990) (0)
- Bypass of quality control in protein folding pathways induces specific misfolding of HIV envelope V2 loop: implications for iminosugars as antivirals (2014) (0)
- Biomedical Aspects of Glycoconjugate Recognition (2009) (0)
- Syncytiotrophoblast membrane N-linked oligosaccharides and their effect on allogeneic reactivity (1989) (0)
- Production of synthetic n-linked glycoconjugate (1992) (0)
- LC-MS based discovery of novel protein biomarkers and their quantitation in HCV fibrosis and NASH diseased human serum (2014) (0)
- Towards the First Antibody-Free Serum Biomarker Assay for NAFLD (2017) (0)
- N-Glycosylation Processing and Glycoprotein Folding—Lessons from the Tyrosinase-Related Proteins (2001) (0)
- Mannan-Binding Lectin Oligomannose Structures for Interaction with IgE and the Accessibility of Identified The Glycosylation of Human Serum IgD and (2004) (0)
- Magnetic Resonance of Biomolecules: By P. F. Knowles, D. Marsh and M. E. W. Rattle, Pp.344. John Wiley & Sons, 1976. £9.75 or $19.75 hardback, £4.75 or $8.75 paperback (1976) (0)
- III HPLC Strategies for Profiling and Sequencing Oligosaccharides (0)
- Integrated strategy for identifying and screening potential cancer biomarkers (2008) (0)
- Human GM3 synthase deficiency: Autosomal recessive infantile onset symptomatic epilepsy syndrome. (2004) (0)
- Perspectives in glycobiology: Glycobiology-concepts, technology and the future (1993) (0)
- Approach to inhibit virus (1988) (0)
- N-Linked Oligosaccharide Expression in Whole Tissue and Specific Glycoproteins of Rodent CNS (1997) (0)
- 5- and 6-membered heterocyclic compounds and pharmaceutically acceptable salt derivatives for use in the treatment of AIDS (1988) (0)
- Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences: 358 (1433) (2003) (0)
- Glycobiology against viruses: Antiviral drug discovery (2006) (0)
- DEOXYNOURIMYCIN AND D-ARABINTOL ANALOGS AND METHODS OF USING CROSS-REFERENCE TO RELATED APPLICATION (2017) (0)
- Comparison by 1H NMR of the hapten environment in the combining site of the dinitrophenyl binding IgA protein 315 and its fragments. (1978) (0)
- Nuclear magnetic resonance studies of macromolecules with fluorine nuclei as probes. (1971) (0)
- A 11 Patent Number : 5 , 525 , 616 45 Date of Patent : Jun . 11 , 1996 (2017) (0)
- 77. Glycosphingolipid profiling of tissues from mouse models of human lysosomal storage disorders (2008) (0)
- Crystal Structure of Fab 2G12 bound to Man1->2Man (2003) (0)
- Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins (2013) (0)
- CD8alpha-alpha in complex with YTS 105.18 Fab (2006) (0)
- Inhibition of Glycosphingolipid Biosynthesis: Application to Lysosomal Storage Disorders (2001) (0)
- Effect of correlation time on the sign of the Overhauser effect in liquids (1966) (0)
- Keystone Symposium on Complex Carbohydrates in Biology and Medicine: Cancer' (2006) (0)
- Proteomics in viral disease (2006) (0)
- Folding and activity of glycoenzymes is dependent on the lectins calnexin and calreticulin (2000) (0)
- Synthesis of 1,5-Dideoxy-3-O-(α-D-mannopyranosyl)-1,5-imino-D- mannitol (XI) and 1,5-Dideoxy-3-O-(α-D-glucopyranosyl)-1,5-imino- D-mannitol (IX): Powerful Inhibitors of Endomannosidase. (1994) (0)
- Crystal Structure of Fab 2G12 bound to Man9GlcNAc2 (2003) (0)
- A process for producing synthetic N-linked glycoconjugates (1990) (0)
- HUMAN IgG glycosylation-DETERMINATION. (1988) (0)
- Glucosidase/protein folding inhibitors as possible mutation-proof, anti-hepatitis B & C agents (2003) (0)
- Apoptosis of Burkitt ' s Lymphoma Cells via Gb 3 / CD 77 , a Neutral Glycolipid Antigen (2005) (0)
- Human GM3 synthase deficiency: A novel form of hereditary childhood epilepsy (2005) (0)
- Differential proteome analysis of CRP-activated platelets (2005) (0)
- New proteomic approaches for biomarker discovery: The search for novel liver fibrosis markers in hepatitis C patients (2014) (0)
- P19-03. Molecular mechanisms for enhancing the antigenicity of the carbohydrate epitope of the broadly neutralizing anti-HIV-1 antibody 2G12 (2009) (0)
- P12-06. A 'non-self' mimic of the natural epitope of anti-HIV antibody 2G12 shows enhanced antigenicity (2009) (0)
- Deactivation of human IgG1 Fc by endoglycosidase treatment (2012) (0)
- Convergent pathways for synthesis and degradation in the quality control of protein folding (2011) (0)
- Proteome analysis of human uveal melanoma cells by two-dimensional gel electrophoresis and mass spectrometry (2005) (0)
- Corrections (2008) (0)
- Recognition of Carbohydrate by Major Histocompatibility Complex Class 1-restricted, Glyeopeptide-specific (2003) (0)
- Substrate reduction therapy in lysosomal storage diseases: a clarification (2004) (0)
- Glycolipid mimetics induce an innate host response and have anti-HBV and HCV activity, in vitro (2004) (0)
- Determining the Structure of Glycan Moieties by Mass Spectrometry (2000) (0)
- “Holistic approaches to glycobiology” (2001) (0)
- derivatives using deoxygalactonojirimycin to inhibition of glycolipid synthesis (1994) (0)
- Book Review:Biological Magnetic Resonance. Lawrence J. Berliner, Jacques Reuben (1980) (0)
- Dwek, Raymond A.: From Antibodies to Glycobiology (2007) (0)
- The Oxford model: The threats and opportunities of commercializing university research (2008) (0)
- Neutron scattering studies oftheisolated Clr2Cis2 sutbunit offirst component ofhumancomplement insolution (1983) (0)
- Spirodiketopiperazines at the Anomeric Position of Mannopyranose: Novel N-Linked Glycopeptides Incorporating an α-Amino Acid at the Anomeric Position of Mannopyranose. (2010) (0)
- 1-N-Glycyl .beta.-oligosaccharide derivatives as stable intermediates for the formation of glycoconjugate probes. [Erratum to document cited in CA117(21):212840h] (1993) (0)
- Glycosylation Studies of Monoclonal Immunoglobulin Deposition Disorders (2004) (0)
- Carbopeptoids: Peptides and Diketopiperazines Incorporating the Anomeric Centre of Mannopyranose. (2001) (0)
- 1,2:3,4-Di-O-isopropylidene-b-D-psicofuranose (2005) (0)
- Table of Contents (1987) (0)
- Clinical diagnosis of liver fibrosis APOL1 using human serum as a biomarker (2007) (0)
- Iminosugars and methods of treating infections caused by arenaviruses (2010) (0)
- Topics in Carbon-13 NMR Spectroscopy, Volume 3 : Edited by George C. Levy Wiley; Brisbane, Chichester, New York, Toronto, 1979 xii + 397 pages. £21.40 (1980) (0)
- Haptens and Antibodies (2007) (0)
- Method for the isolation of unreduced oligosaccharides from glycoproteins and glycohormones (1986) (0)
- Obituary: Alan Williams 1945–1992 (1992) (0)
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