Raymond Gesteland

Raymond Gesteland's AcademicInfluence.com Rankings

Raymond Gesteland

Biology

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#11549

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Genetics

#849

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#943

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Biology

Why Is Raymond Gesteland Influential?

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According to Wikipedia, Raymond Gesteland is an American geneticist, currently Distinguished Professor Emeritus at University of Utah. He received his Ph.D. at Harvard University in Biochemistry and his B.S. and M.S. at the University of Wisconsin, also in Biochemistry.

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Raymond Gesteland's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The neurofibromatosis type 1 gene encodes a protein related to GAP (1990) (1068)
A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations (1990) (1055)
New goals for the U.S. Human Genome Project: 1998-2003. (1998) (838)
Processing of Adenovirus 2-Induced Proteins (1973) (658)
The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae (1990) (637)
Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme (1995) (473)
Deletion of Selenoprotein P Alters Distribution of Selenium in the Mouse* (2003) (431)
Isolation and characterization of ribonuclease I mutants of Escherichia coli. (1966) (387)
A dual-luciferase reporter system for studying recoding signals. (1998) (379)
Recoding: dynamic reprogramming of translation. (1996) (337)
Capillary gel electrophoresis for rapid, high resolution DNA sequencing. (1990) (300)
Primary structure of the Saccharomyces cerevisiae GAL4 gene (1984) (253)
Life Before DNA. (Book Reviews: The RNA World. The Nature of Modern RNA Suggests a Prebiotic RNA World.) (1993) (251)
Slippery runs, shifty stops, backward steps, and forward hops: -2, -1, +1, +2, +5, and +6 ribosomal frameshifting. (1987) (242)
The signal for a leaky UAG stop codon in several plant viruses includes the two downstream codons. (1991) (226)
Recoding: translational bifurcations in gene expression. (2002) (218)
SOME PHYSICAL PROPERTIES OF BACTERIOPHAGE R17 AND ITS RIBONUCLEIC ACID. (1964) (217)
In vitro Synthesis of Bacteriophage Lysozyme (1967) (216)
Direct repeats flank three small nuclear RNA pseudogenes in the human genome (1981) (216)
Location and identification of the genes for adenovirus type 2 early polypeptides (1976) (213)
Reading frame switch caused by base‐pair formation between the 3′ end of 16S rRNA and the mRNA during elongation of protein synthesis in Escherichia coli. (1988) (210)
Enhanced differential synthesis of proteins in a mammalian cell-free system by addition of polyamines. (1975) (209)
Unfolding of Escherichia coli ribosomes by removal of magnesium. (1966) (208)
Programmed ribosomal frameshifting in decoding the SARS-CoV genome (2005) (205)
Translation of MuLV and MSV RNAs in nuclease-treated reticulocyte extracts: Enhancement of the gag-pol polypeptide with yeast suppressor tRNA (1978) (197)
Ribosome gymnastics—Degree of difficulty 9.5, style 10.0 (1990) (185)
Recoding: reprogrammed genetic decoding. (1992) (177)
Evidence that a downstream pseudoknot is required for translational read-through of the Moloney murine leukemia virus gag stop codon. (1991) (155)
E. coli ribosomes re-phase on retroviral frameshift signals at rates ranging from 2 to 50 percent. (1989) (152)
The adsorption of bacteriophage R-17 (1964) (142)
Probing the structure of the Escherichia coli 10Sa RNA (tmRNA). (1997) (139)
Stimulation of stop codon readthrough: frequent presence of an extended 3′ RNA structural element (2011) (138)
Transcriptional slippage occurs during elongation at runs of adenine or thymine in Escherichia coli. (1990) (138)
Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: antizyme 3. (2000) (131)
rRNA-mRNA base pairing stimulates a programmed -1 ribosomal frameshift (1994) (131)
Isolation and preliminary characterization of the GAL4 gene, a positive regulator of transcription in yeast. (1982) (123)
Mapping of late adenovirus genes by cell-free translation of RNA selected by hybridization to specific DNA fragments. (1975) (121)
RNA worlds : from life's origins to diversity in gene regulation (2011) (119)
Normal tRNAs promote ribosomal frameshifting (1979) (118)
Readthrough of dystrophin stop codon mutations induced by aminoglycosides (2004) (114)
Presence and location of modified nucleotides in Escherichia coli tmRNA: structural mimicry with tRNA acceptor branches (1998) (114)
A second mammalian antizyme: conservation of programmed ribosomal frameshifting. (1998) (108)
Cell-free synthesis of adenovirus 2 proteins programmed by fractionated messenger RNA: a comparison of polypeptide products and messenger RNA lengths. (1974) (106)
Synthesis of polyoma proteins in vitro. (1973) (106)
The Selenium-rich C-terminal Domain of Mouse Selenoprotein P Is Necessary for the Supply of Selenium to Brain and Testis but Not for the Maintenance of Whole Body Selenium* (2007) (102)
Human U1 Loci: Genes for human U1 RNA have dramatically similar genomic environments (1982) (100)
Conservation of polyamine regulation by translational frameshifting from yeast to mammals (2000) (100)
The 22nd Amino Acid (2002) (100)
Structural probing and mutagenic analysis of the stem-loop required for Escherichia coli dnaX ribosomal frameshifting: programmed efficiency of 50%1 (1997) (98)
Frameshifting in gene 10 of bacteriophage T7 (1991) (97)
P-site tRNA is a crucial initiator of ribosomal frameshifting. (2004) (94)
Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit (2000) (93)
Multiwavelength fluorescence detection for DNA sequencing using capillary electrophoresis. (1991) (93)
Ribosomal frameshifting from -2 to +50 nucleotides. (1990) (92)
Reading two bases twice: mammalian antizyme frameshifting in yeast. (1996) (90)
Recoding : expansion of decoding rules enriches gene expression (2010) (90)
Thermodynamic calculations and statistical correlations for oligo-probes design. (2003) (89)
Sequences that direct significant levels of frameshifting are frequent in coding regions of Escherichia coli (2003) (86)
Towards a genetic dissection of the basis of triplet decoding, and its natural subversion: programmed reading frame shifts and hops. (1991) (86)
A Functional –1 Ribosomal Frameshift Signal in the Human Paraneoplastic Ma3 Gene* (2006) (85)
Nonlinearity in genetic decoding: homologous DNA replicase genes use alternatives of transcriptional slippage or translational frameshifting. (2000) (82)
Computational identification of putative programmed translational frameshift sites (2002) (81)
Pseudoknot‐dependent read‐through of retroviral gag termination codons: importance of sequences in the spacer and loop 2. (1994) (81)
Release factor 2 frameshifting sites in different bacteria (2002) (80)
A rapid in vitro method for obtaining RNA accessibility patterns for complementary DNA probes: correlation with an intracellular pattern and known RNA structures. (1997) (78)
Analysis of the roles of tRNA structure, ribosomal protein L9, and the bacteriophage T4 gene 60 bypassing signals during ribosome slippage on mRNA. (2001) (77)
Identification of sequence motifs in oligonucleotides whose presence is correlated with antisense activity. (2000) (72)
Translation: The twenty-first amino acid (2000) (70)
Transcriptional slippage in bacteria: distribution in sequenced genomes and utilization in IS element gene expression (2005) (70)
Thermodynamic criteria for high hit rate antisense oligonucleotide design. (2003) (69)
Gene Order in the Bacteriophage R17 RNA : 5′–;A Protein–Coat Protein–Synthetase–3′ (1970) (69)
One protein from two open reading frames: mechanism of a 50 nt translational bypass (2000) (68)
Coupling of open reading frames by translational bypassing. (2000) (67)
tRNA hopping: enhancement by an expanded anticodon. (1989) (66)
RECODE: a database of frameshifting, bypassing and codon redefinition utilized for gene expression (2001) (65)
Programmed ribosomal frameshifting: much ado about knotting! (1999) (62)
An efficient Shine-Dalgarno sequence but not translation is necessary for lacZ mRNA stability in Escherichia coli (1994) (61)
Functional and structural analysis of a pseudoknot upstream of the tag-encoded sequence in E. coli tmRNA. (1999) (61)
Efficient stimulation of site-specific ribosome frameshifting by antisense oligonucleotides. (2004) (60)
Stability of capillary gels for automated sequencing of DNA (1992) (60)
A mutation in ribosomal protein L9 affects ribosomal hopping during translation of gene 60 from bacteriophage T4. (1994) (60)
The genes sup-7 X and sup-5 III of C. elegans suppress amber nonsense mutations via altered transfer RNA (1983) (59)
Yeast suppressors of UAA and UAG nonsense codons work efficiently in vitro via tRNA (1976) (58)
Programmed translational −1 frameshifting on hexanucleotide motifs and the wobble properties of tRNAs (2003) (57)
Quadruplet codons: implications for code expansion and the specification of translation step size. (2000) (56)
An analysis of sequences stimulating frameshifting in the decoding of gene 10 of bacteriophage T7. (1991) (55)
Class of promoter sites for Escherichia coli DNA-dependent RNA polymerase (1974) (55)
Expression Levels Influence Ribosomal Frameshifting at the Tandem Rare Arginine Codons AGG_AGG and AGA_AGA in Escherichia coli (2005) (52)
Functional tRNAs with altered 3′ ends. (1993) (52)
tRNA anticodon replacement experiments show that ribosomal frameshifting can be caused by doublet decoding. (1986) (51)
Influence of the stacking potential of the base 3' of tandem shift codons on -1 ribosomal frameshifting used for gene expression. (2002) (50)
Electrophoretic analysis of proteins from normal and cesium chloride-treated Escherichia coli ribosomes. (1967) (49)
Structural studies of the RNA pseudoknot required for readthrough of the gag-termination codon of murine leukemia virus. (1999) (49)
Analysis of leaky viral translation termination codons in vivo by transient expression of improved β-glucuronidase vectors (1990) (48)
Ribosomal protein L9 interactions with 23 S rRNA: the use of a translational bypass assay to study the effect of amino acid substitutions. (1996) (48)
Identification of two proteins encoded by the Saccharomyces cerevisiae GAL4 gene (1984) (47)
Folding of an mRNA pseudoknot required for stop codon readthrough: effects of mono- and divalent ions on stability. (1997) (47)
Pattern of Protein Synthesis in Monkey Cells Infected by Simian Virus 40 (1972) (47)
A nickel complex cleaves uridine in folded RNA structures: application to E. coli tmRNA and related engineered molecules. (1998) (46)
A three-way junction and constituent stem-loops as the stimulator for programmed -1 frameshifting in bacterial insertion sequence IS911. (1999) (46)
The 23 S rRNA environment of ribosomal protein L9 in the 50 S ribosomal subunit. (2000) (46)
Seven, eight and nine-membered anticodon loop mutants of tRNA(2Arg) which cause +1 frameshifting. Tolerance of DHU arm and other secondary mutations. (1992) (46)
Characterization of ribosomal frameshift events by protein sequence analysis. (1986) (45)
Maintenance of the correct open reading frame by the ribosome (2003) (45)
A case for trans translation (1996) (45)
Overriding standard decoding: implications of recoding for ribosome function and enrichment of gene expression. (2001) (44)
Genome-based peptide fingerprint scanning (2002) (42)
Specific cleavage of bacteriophage R17 RNA by an endonuclease isolated from E. coli MRE-600. (1968) (42)
Characterization of polypeptides made in vitro from bacteriophage lambda DNA. (1973) (42)
Polyamine sensing during antizyme mRNA programmed frameshifting. (2005) (41)
Recode 2003 (2003) (39)
Programmed frameshifting in the synthesis of mammalian antizyme is +1 in mammals, predominantly +1 in fission yeast, but -2 in budding yeast. (1998) (39)
Binding Site on R17 RNA for Coat Protein (1969) (39)
A novel soybean mitochondrial transcript resulting from a DNA rearrangement involving the 5S rRNA gene. (1984) (38)
Cell culture analysis of the regulatory frameshift event required for the expression of mammalian antizymes (2001) (38)
Translation of bacteriophage R17 and Qbeta RNA in a mammalian cell-free system. (1973) (38)
Flexibility of the nascent polypeptide chain within the ribosome--contacts from the peptide N-terminus to a specific region of the 30S subunit. (1998) (37)
Structural organization of Escherichia coli tmRNA. (1996) (36)
Localization of human U1 small nuclear RNA genes to band p36.3 of chromosome 1 by in situ hybridization (1984) (36)
The Drosophila Gene for Antizyme Requires Ribosomal Frameshifting for Expression and Contains an Intronic Gene for snRNP Sm D3 on the Opposite Strand (1998) (35)
Factors That Influence Selection of Coding Resumption Sites in Translational Bypassing (2004) (35)
Drop-off during ribosome hopping. (2001) (34)
Comparative studies of frameshifting and nonframeshifting RNA pseudoknots: a mutational and NMR investigation of pseudoknots derived from the bacteriophage T2 gene 32 mRNA and the retroviral gag-pro frameshift site. (2002) (32)
In vitro suppression of UAG and UGA mutants in the thymidine kinase gene of herpes simplex virus. (1979) (31)
Utilization of selenocysteyl-tRNA[Ser]Sec and seryl-tRNA[Ser]Sec in protein synthesis. (1994) (31)
A new procedure for the preparation of highly labeled intact 32P RNA from bacteriophage R-17. (1970) (30)
Upstream stimulators for recoding. (1995) (30)
Identification of a New Antizyme mRNA +1 Frameshifting Stimulatory Pseudoknot in a Subset of Diverse Invertebrates and its Apparent Absence in Intermediate Species (2004) (29)
Diverse bacterial genomes encode an operon of two genes, one of which is an unusual class-I release factor that potentially recognizes atypical mRNA signals other than normal stop codons (2006) (29)
A multi‐recombination model for the mtDNA rearrangements seen in maize cmsT regenerated plants (1992) (29)
Enzyme-linked fluorescent detection for automated multiplex DNA sequencing. (1994) (29)
The role of EF-Tu and other translation components in determining translocation step size. (1990) (28)
Artificial neural network prediction of antisense oligodeoxynucleotide activity. (2002) (28)
Phylogenetic analysis of tmRNA genes within a bacterial subgroup reveals a specific structural signature. (2001) (26)
Uridine-33 in yeast tRNA not essential for amber suppression (1983) (26)
Eubacterial tmRNAs: everywhere except the alpha-proteobacteria? (1999) (26)
Evaluation of random cDNA clones as probes for human restriction fragment polymorphisms. (1983) (24)
Chimeric organization of two genes for the soybean mitochondrial ATPase subunit 6 (2004) (24)
Discontinuous Triplet Decoding with or without Re-Pairing by Peptidyl tRNA (1995) (24)
Maize mitochondrial DNA rearrangements between the normal type, the Texas male sterile cytoplasm, and a fertile revertant cms-T regenerated plant (1987) (23)
Evolutionary specialization of recoding: frameshifting in the expression of S. cerevisiae antizyme mRNA is via an atypical antizyme shift site but is still +1. (2006) (22)
Characterization of small nuclear RNA U1 gene candidates and pseudogenes from the human genome. (1981) (22)
Bends in SV40 DNA: use of mutagenesis to identify the critical bases involved. (1988) (22)
Replacement of anticodon loop nucleotides to produce functional tRNAs: amber suppressors derived from yeast tRNAPhe. (1982) (21)
Plant tRNA genes: putative soybean genes for tRNAasp and tRNAmet. (1985) (21)
Guanine tracts enhance sequence directed DNA bends. (1990) (21)
Identification of amber and ochre mutants of the human virus Ad2+ND1. (1977) (21)
In vitro synthesis of T4 lysozyme by suppression of amber mutations. (1967) (21)
ODNBase-a web database for antisense oligonucleotide effectiveness studies (2000) (20)
Rapid cycle sequencing in an air thermal cycler. (1993) (19)
The origin and destiny of adenovirus proteins. (1975) (19)
Biochemistry. The 22nd amino acid. (2002) (19)
Saturation mutagenesis of a DNA region of bend. Base steps other than ApA influence the bend. (1990) (18)
Poking a Hole in the Sanctity of the Triplet Code: Inferences for Framing (2000) (17)
Characterization of lysozyme messenger and lysozyme synthesized in vitro. (1969) (17)
An automated film reader for DNA sequencing based on homomorphic deconvolution (1994) (17)
Simian virus 40-specific polypeptides in AD2+ ND1- and Ad2+ ND4-infected cells (1976) (16)
Mutants of translational components that alter reading frame by two steps forward or one step back. (1988) (16)
Complex organization of the soybean mitochondrial genome: recombination repeats and multiple transcripts at the atpA loci (1993) (16)
Suppression of amber mutants in vitro induced by low temperature. (1978) (16)
P-site pairing subtleties revealed by the effects of different tRNAs on programmed translational bypassing where anticodon re-pairing to mRNA is separated from dissociation. (2005) (16)
Serine-inserting UAA suppression mediated by yeast tRNASer. (1981) (16)
Translation of R-17 RNA fragments. (1969) (15)
Reported translational bypass in a trpR'-lacZ' fusion is accounted for by unusual initiation and +1 frameshifting. (1997) (15)
Effects of Dietary Sodium Fluoride on Dairy Cows. VI. In Young Heifers (1961) (15)
24 Dynamics of the Genetic Code (1999) (15)
Line scanning system for direct digital chemiluminescence imaging of DNA sequencing blots. (1993) (14)
Does antizyme exist in Escherichia coli? (1998) (13)
Synthesis of Bacteriophage λ Proteins in vitro (1972) (12)
1 Physical Properties of RNA Bacteriophages and Their RNA (1975) (12)
−1 Frameshifting at a CGA AAG Hexanucleotide Site Is Required for Transposition of Insertion Sequence IS1222 (2004) (12)
Novel antizyme gene in Danio rerio expressed in brain and retina. (2007) (11)
Polyamine analogs with xylene rings induce antizyme frameshifting, reduce ODC activity, and deplete cellular polyamines. (2006) (11)
Intricacies of ribosomal frameshifting (1999) (11)
Assignment of the human antizyme gene (OAZ) to chromosome 19p13.3 by fluorescence in situ hybridization. (1996) (10)
tRNA and mRNA both in the same molecule (1996) (10)
Decoding of tandem quadruplets by adjacent tRNAs with eight-base anticodon loops. (2000) (10)
Electrophoresis, autoradiography and electroblotting of peptides: T4 gene 60 hopping. (1992) (9)
Low fluorescence background electroblotting membrane for DNA sequencing (1992) (9)
Cell-free synthesis of herpes simplex virus proteins (1977) (9)
Structure of human ornithine decarboxylase antizyme 2 gene. (1999) (8)
Purification and Properties of a New Enzyme from Escherichia coli: Nucleoside Phosphoacyl Hydrolase (1970) (8)
Genomes to Life "Center for Molecular and Cellular Systems": a research program for identification and characterization of protein complexes. (2002) (7)
The forms of tRNATrp found in avian sarcoma virus and uninfected chicken cells have structural identity but functional distinctions. (1980) (7)
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides: application to HIV genome (2004) (6)
Resolution of the discrepancy between a gene translation--termination codon and the deduced sequence for release of the encoded polypeptide. (1983) (5)
Effects of 3'-terminal phosphates in RNA produced by ribozyme cleavage. (1998) (5)
16 The Shapely mRNA: Knotting Ventured, Knotting Gained (2006) (5)
Messenger Ribonucleic Acids from Mutant Myeloma Cells (1975) (5)
Uninterrupted translation through putative 12-nucleotide coding gap in sequence of carA: business as usual (1994) (5)
A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations. (1990) (5)
Reloading and stability of polyacrylamide slab gels for automated DNA sequencing. (1994) (4)
The synthetase gene of the RNA phages R17, MS2 and f2 has a single UAG terminator codon (1975) (4)
THE ASSOCIATION FOR MOLECULAR PATHOLOGY, THE AMERICAN COLLEGE OF MEDICAL GENETICS, THE AMERICAN SOCIETY FOR CLINICAL PATHOLOGY, THE COLLEGE OF AMERICAN PATHOLOGISTS, HAIG KAZAZIAN, MD, (2010) (3)
Bringing RNA into View: RNA and Its Roles in Biology. (2000) (3)
Sequence of E.coli K12 valU operon which contains 3 genes for tRNA(Val1) and 1 gene for tRNA(Lys). (1990) (3)
Imaging of fluorescent and chemiluminescent DNA hybrids using a 2-D CCD camera (1990) (2)
Erratum: A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations (Cell 62, 193-201, 1990; July 13 issue) (1990) (2)
mRNA readout at 40 (2001) (2)
Location of identification of the genes for adenovirus type 2 polypeptides. (1976) (1)
Class of promotor sites for Escherichia coli DNA-dependent RNA polymerase. (1974) (1)
Mutants of tRNA, Ribosomes and mRNA Affecting Frameshifting, Hopping or Stop Codon Read-Through (1993) (1)
PROPERTIES OF A YEAST tRNAPhe AMBER SUPPRESSOR (1982) (1)
Degeneracy of the Genetic Code (2002) (1)
Synthesis of bacteriophage lambda proteins in vitro. (1972) (1)
Recoding: Site- or mRNA-Specific Alteration of Genetic Readout Utilized for Gene Expression (2013) (0)
Macromolecular Synthesis and Growth. Ronald A. Malt (1969) (0)
business as usual. 12-nucleotide coding gap in sequence of carA: Uninterrupted translation through putative (2013) (0)
News & Views Layout (1999) (0)
Science Education on the Internet: Conference for Developers of OnLine Curricula ''Learning Strategies for Science Education Websites'' (2000) (0)
Erratum: Quadruplet codons: Implications for code expansion and the specification of translation step size (Journal of Molecular Biology (2000) 298 (195-209)) (2000) (0)
Features of the gene 60 nascent peptide, an in cis element of the translationa bypass (1996) (0)
Preface/Front Matter (1993) (0)
23 Regulatory Recoding (1996) (0)
Advanced Sequencing Technology - Final Technical Report for period February 1, 1994 to January 31, 1997 (1997) (0)
DOI: 10.1126/science.282.5389.682 (2008) (0)
Erratum: The role of EF-Tu and other translation components in determining translocation step size (BBAEXP 92116) (Biochimica et Biophysica Acta, Vol 1050 (1990) 274-278)) (1990) (0)
Crystallization of the MS2 translational repressor alone and complexed to bromouridine (1995) (0)
The efficiency of gene 60 translational bypass revisited (1996) (0)
Advanced sequenching technology (1992) (0)
24of the Genetic Code (1999) (0)
The C‐terminal Domain of Selenoprotein P Is Needed for Maintenance of Selenium Homeostasis (2006) (0)
Gene Expression: Frameshifting (2007) (0)
Saving Science, Saving Lives: Why Choices You Make When Publishing Matter (2003) (0)
AnEfficient Shine-Dalgarno Sequence butNotTranslation Is Necessary forlacZmRNA Stability inEscherichia coli (1994) (0)
Analysis of Antisense Oligodeoxynucleotides Based on Sequence Motif Content to Predict Effectiveness (2000) (0)
Bacteriophage T4 lysozyme mRNA. (1969) (0)
Replacement of anticodon-loop nucleotides to produce functional tRNAs (1984) (0)
Advanced sequenching technology. Second year progress report (1992) (0)
Purification and properties of a new enzyme from Escherichia coli: nucleoside phosphocyl hydrolase. (1970) (0)
Recoding: getting more out of the message by shifting reading frame and redefining codon meaning (2008) (0)

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