Rebecca Heald
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Biology
Rebecca Heald's Degrees
- PhD Molecular and Cell Biology University of California, Berkeley
- Bachelors Biology Stanford University
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Why Is Rebecca Heald Influential?
(Suggest an Edit or Addition)According to Wikipedia, Rebecca W. Heald is an American professor of cell and developmental biology. She is currently a Professor in the Department of Molecular & Cell Biology at the University of California, Berkeley. In May 2019, she was elected to the National Academy of Sciences. She has published over 120 research articles in peer reviewed journals.
Rebecca Heald's Published Works
Published Works
- Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts (1996) (980)
- Genome evolution in the allotetraploid frog Xenopus laevis (2016) (691)
- Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis (1990) (608)
- Visualization of a Ran-GTP Gradient in Interphase and Mitotic Xenopus Egg Extracts (2002) (574)
- Dissection of the Mammalian Midbody Proteome Reveals Conserved Cytokinesis Mechanisms (2004) (506)
- Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated cdc2 kinase (1993) (449)
- A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity (1998) (415)
- Analysis of a RanGTP-regulated gradient in mitotic somatic cells (2006) (381)
- Mechanisms of mitotic spindle assembly and function. (2008) (370)
- Importin β Is a Mitotic Target of the Small GTPase Ran in Spindle Assembly (2001) (362)
- Spindle Assembly in Xenopus Egg Extracts: Respective Roles of Centrosomes and Microtubule Self-Organization (1997) (355)
- Mechanisms and Molecules of the Mitotic Spindle (2004) (351)
- Formation of Spindle Poles by Dynein/Dynactin-Dependent Transport of Numa (2000) (342)
- The RanGTP gradient – a GPS for the mitotic spindle (2008) (284)
- A Rae1-Containing Ribonucleoprotein Complex Is Required for Mitotic Spindle Assembly (2005) (275)
- Cytoplasmic Volume Modulates Spindle Size During Embryogenesis (2013) (217)
- Importin beta is a mitotic target of the small GTPase Ran in spindle assembly. (2001) (212)
- Importazole, a small molecule inhibitor of the transport receptor importin-β. (2011) (207)
- Nuclear Size Is Regulated by Importin α and Ntf2 in Xenopus (2010) (206)
- Katanin Contributes to Interspecies Spindle Length Scaling in Xenopus (2011) (186)
- Genome-wide analysis demonstrates conserved localization of messenger RNAs to mitotic microtubules (2007) (173)
- Investigating mitotic spindle assembly and function in vitro using Xenopus laevis egg extracts (2006) (148)
- Thirty years of search and capture: The complex simplicity of mitotic spindle assembly (2015) (143)
- Histone H1 is essential for mitotic chromosome architecture and segregation in Xenopus laevis egg extracts (2005) (136)
- A computational model predicts Xenopus meiotic spindle organization (2010) (136)
- Altered actin and troponin binding of amino-terminal variants of chicken striated muscle alpha-tropomyosin expressed in Escherichia coli. (1987) (126)
- Motor Function in the Mitotic Spindle Minireview (2000) (120)
- REEP3/4 ensure endoplasmic reticulum clearance from metaphase chromatin and proper nuclear envelope architecture. (2013) (115)
- Mechanisms of intracellular scaling. (2012) (114)
- Xenopus tropicalis egg extracts provide insight into scaling of the mitotic spindle (2007) (107)
- Mitotic spindle scaling during Xenopus development by kif2a and importin α (2013) (107)
- The structure of the amino terminus of tropomyosin is critical for binding to actin in the absence and presence of troponin. (1988) (106)
- Methods for studying spindle assembly and chromosome condensation in Xenopus egg extracts. (2006) (101)
- Cell structure and dynamics. (2011) (98)
- Regulation of Op18 during Spindle Assembly in Xenopus Egg Extracts (2001) (98)
- The perichromosomal layer (2005) (95)
- Nuclear actin and protein 4.1: Essential interactions during nuclear assembly in vitro (2003) (93)
- A Comparative Analysis of Spindle Morphometrics across Metazoans (2015) (88)
- Motor function in the mitotic spindle. (2000) (87)
- Centrosome proteins form an insoluble perinuclear matrix during muscle cell differentiation (2009) (81)
- Importin α Partitioning to the Plasma Membrane Regulates Intracellular Scaling (2019) (77)
- TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts (2014) (69)
- Xorbit/CLASP links dynamic microtubules to chromosomes in the Xenopus meiotic spindle (2006) (68)
- Mitotic noncoding RNA processing promotes kinetochore and spindle assembly in Xenopus (2016) (67)
- Interplay between spindle architecture and function. (2013) (67)
- Micromanipulation studies of chromatin fibers in Xenopus egg extracts reveal ATP-dependent chromatin assembly dynamics. (2006) (64)
- Microtubules: 50 years on from the discovery of tubulin (2016) (63)
- A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts. (1999) (61)
- Identification of a novel protein regulating microtubule stability through a chemical approach. (2004) (59)
- The condensin complex is required for proper spindle assembly and chromosome segregation in Xenopus egg extracts (2003) (59)
- Morphology and function of membrane-bound organelles. (2014) (51)
- Paternal chromosome loss and metabolic crisis contribute to hybrid inviability in Xenopus (2017) (51)
- Multiple Domains of Human CLASP Contribute to Microtubule Dynamics and Organization In Vitro and in Xenopus Egg Extracts (2012) (48)
- Chromosome movement: Dynein-out at the kinetochore (2001) (47)
- Microtubule-based motor function in mitosis. (1999) (47)
- Mitotic Spindle Assembly around RCC1-Coated Beads in Xenopus Egg Extracts (2011) (45)
- Histone H1 compacts DNA under force and during chromatin assembly (2012) (41)
- Synthesis and biological evaluation of myoseverin derivatives: microtubule assembly inhibitors. (2001) (40)
- Spindles get the ran around. (2000) (40)
- Xnf7 Contributes to Spindle Integrity through Its Microtubule-Bundling Activity (2005) (38)
- Two Distinct Domains of Protein 4.1 Critical for Assembly of Functional Nuclei in Vitro * (2002) (38)
- N-terminal phosphorylation of p60 katanin directly regulates microtubule severing. (2013) (37)
- Discovery of selective aminothiazole aurora kinase inhibitors. (2008) (37)
- Biological Scaling Problems and Solutions in Amphibians. (2015) (37)
- Adenomatous Polyposis Coli Associates with the Microtubule-Destabilizing Protein XMCAK (2004) (34)
- Mitotic chromosome size scaling in Xenopus (2011) (33)
- Enzymatically Generated CRISPR Libraries for Genome Labeling and Screening. (2015) (33)
- RanGTP and CLASP1 cooperate to position the mitotic spindle (2013) (32)
- The Long and the Short of it: Linker Histone H1 is Required for Metaphase Chromosome Compaction (2006) (30)
- Essential roles for cohesin in kinetochore and spindle function in Xenopus egg extracts (2006) (28)
- Preparation of Cellular Extracts from Xenopus Eggs and Embryos. (2018) (27)
- Microtubule dynamics. (2002) (27)
- Subcellular scaling: does size matter for cell division? (2018) (25)
- Functional Comparison of H1 Histones in Xenopus Reveals Isoform-Specific Regulation by Cdk1 and RanGTP (2010) (24)
- Two Protein 4.1 Domains Essential for Mitotic Spindle and Aster Microtubule Dynamics and Organization in Vitro* (2004) (24)
- Katanin-like protein Katnal2 is required for ciliogenesis and brain development in Xenopus embryos. (2018) (24)
- Regulatory remodeling in the allo-tetraploid frog Xenopus laevis (2017) (21)
- SnapShot: Motor Proteins in Spindle Assembly (2008) (20)
- A dynamic duo of microtubule modulators (2000) (20)
- Analysis of microtubule polymerization in vitro and during the cell cycle in Xenopus egg extracts. (2006) (19)
- Glutamylation of Nap1 modulates histone H1 dynamics and chromosome condensation in Xenopus (2015) (18)
- Atomic force microscope imaging of chromatin assembled in Xenopus laevis egg extract (2010) (16)
- Kif2a Scales Meiotic Spindle Size in Hymenochirus boettgeri (2019) (14)
- Role of chromosomes in assembly of meiotic and mitotic spindles. (1997) (14)
- A versatile multivariate image analysis pipeline reveals features of Xenopus extract spindles (2016) (13)
- Scratch n' screen for inhibitors of cell migration. (2005) (13)
- Methods for the study of centrosome-independent spindle assembly in Xenopus extracts. (2001) (12)
- Transcription brings the complex(ity) to the centromere (2017) (12)
- Kinetochore function: The complications of becoming attached (2001) (12)
- Xenopus Hybrids Provide Insight Into Cell and Organism Size Control (2018) (11)
- Centrosomes and kinetochores, who needs 'Em? The role of noncentromeric chromatin in spindle assembly. (2003) (8)
- Identification and characterization of centromeric sequences in Xenopus laevis (2020) (7)
- Mitotic Spindle Assembly Mechanisms (2009) (7)
- Regulation of Op 18 during Spindle Assembly in Xenopus Egg Extracts (2001) (7)
- Serving Up a Plate of Chromosomes (2006) (6)
- Spindle assembly in egg extracts of the Marsabit clawed frog, Xenopus borealis (2018) (6)
- TPX 2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts (2014) (6)
- Xenopus Egg Extracts Increase Dynamics of Histone H1 on Sperm Chromatin (2010) (5)
- Correction: Mitotic noncoding RNA processing promotes kinetochore and spindle assembly in Xenopus (2016) (5)
- Cell division: Burning the spindle at both ends (2004) (5)
- Emergent properties of mitotic chromosomes. (2020) (5)
- The power of amphibians to elucidate mechanisms of size control and scaling. (2020) (5)
- Generation of Xenopus Haploid, Triploid, and Hybrid Embryos. (2019) (4)
- Scaling of biosynthesis and metabolism with cell size (2022) (4)
- Cryptic no longer: arrays of CLASP1 TOG domains. (2013) (4)
- Challenges facing the biologist doing chemical genetics (2006) (4)
- The Incredible Shrinking Spindle. (2018) (3)
- Size Control in Biology: From Organelles to Organisms (2015) (3)
- The Use of Cell-Free Xenopus Extracts to Investigate Cytoplasmic Events. (2018) (3)
- Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs (2021) (3)
- Dodecaploid Xenopus longipes provides insight into the emergence of size scaling relationships during development (2022) (3)
- In vitro Assays for Mitotic Spindle Assembly and Function (2006) (3)
- Cell biology. Serving up a plate of chromosomes. (2006) (2)
- A lab co-op helps young faculty members to thrive (2018) (2)
- Endgame: AIDS in black America (2012) (2)
- Molecular conflicts disrupting centromere maintenance contribute to Xenopus hybrid inviability (2022) (2)
- Altering membrane topology with Sar1 does not impair spindle assembly in Xenopus egg extracts (2012) (2)
- Centromere Glue Provides Spindle Cue (2004) (2)
- Infectious disease surveillance update (2012) (2)
- RUVs drive chromosome decondensation after mitosis. (2014) (2)
- Mechanisms of Mitotic Spindle Assembly and Function (2007) (2)
- Cell Biology: The Health Hazards of Super-Sizing (2019) (1)
- Brinkley-fest of mitosis. (2007) (1)
- A DNA Crosslinker Collects Mitotic Chromosomes. (2017) (1)
- Regulatory remodeling in the allo-tetraploid frog Xenopus laevis (2017) (1)
- Faculty Opinions recommendation of Human chromokinesin KIF4A functions in chromosome condensation and segregation. (2004) (1)
- Ploidy modulates cell size and metabolic rate in Xenopus embryos (2022) (1)
- Mitotic spindles and microtubule dynamics inXenopusegg extracts (1996) (1)
- Chromosome congression: another fine mesh we've gotten into. (2005) (1)
- Faculty Opinions recommendation of Reconstitution of physiological microtubule dynamics using purified components. (2002) (1)
- Reconstitution of muscle cell microtubule organization in vitro (2022) (1)
- Mitotic Spindle Assembly In Vitro (2001) (1)
- How to explain Parkinson's disease to a child Virginia Ironside (2014) (0)
- Faculty Opinions recommendation of The microtubule-destabilizing kinesin XKCM1 is required for chromosome positioning during spindle assembly. (2002) (0)
- Mitotic chromosomes scale to nucleo-cytoplasmic ratio and cell size in Xenopus (2022) (0)
- Nuclear actin is essential for assembly and maintenance of nuclear structure (2003) (0)
- Polyploidy in Xenopus lowers metabolic rate by decreasing total cell surface area (2023) (0)
- model predicts Xenopus meiotic spindle organization. (2010) (0)
- A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: Biochemical identification using Xenopus egg extracts (chemical librariesycell cycle) (1999) (0)
- Faculty Opinions recommendation of A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. (2002) (0)
- Mechanisms of Nuclear, Spindle and Mitotic Chromosome Scaling (2012) (0)
- Characterization of a novel cdk inhibitor using Xenopus egg extracts. (1998) (0)
- A chemistry-based approach to identify factors involved in spindle assembly (1999) (0)
- ReviewMechanisms and Molecules of the Mitotic Spindle (2018) (0)
- spindle scaling during development by kif2a and importin α. (2013) (0)
- egg extracts increase dynamics of histone H1 on sperm (2010) (0)
- Monitoring the compaction of single DNA molecules in Xenopus egg extract in real time (2023) (0)
- Micromanipulation studies of chromatin fibers in Xenopus egg extracts reveal ATP-dependent nucleosome assembly dynamics (2017) (0)
- The Role of Chromosome Architecture in Spindle Assembly and Anaphase: The Condensed Version (2003) (0)
- Faculty Opinions recommendation of C. elegans condensin promotes mitotic chromosome architecture, centromere organization, and sister chromatid segregation during mitosis and meiosis. (2002) (0)
- Author response: Mitotic spindle scaling during Xenopus development by kif2a and importin α (2012) (0)
- Faculty Opinions recommendation of Developmental regulation of central spindle assembly and cytokinesis during vertebrate embryogenesis. (2008) (0)
- Title Enzymatically Generated CRISPR Libraries for Genome Labeling and Screening Permalink (0)
- Molecular conflicts disrupting centromere assembly contribute to Xenopus hybrid inviability (2022) (0)
- Limiting Cytoplasmic Components Couple Spindle Size to Cell Size during Embryogenesis (2014) (0)
- Observing dynamics of chromatin fibers in Xenopus egg extracts by single DNA manipulation using a transverse magnetic tweezer setup (2005) (0)
- Faculty Opinions recommendation of Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis. (2003) (0)
- 54th ASTRO annual meeting (2012) (0)
- Infectious disease surveillance update (2012) (0)
- Session 11 fast static RAMs (1987) (0)
- The Role of Ran in Mitosis (2003) (0)
- Symposium: Chromosome Architecture and Function (2012) (0)
- Durhane Wong-Rieger: championing patients. (2014) (0)
- PTEN link between cancer and diabetes (2012) (0)
- Cover Image, Volume 75, Issue 6 (2018) (0)
- Yellow Jack: chaos in Memphis (2013) (0)
- Ashamed to die (2012) (0)
- Rebecca Heald (2010) (0)
- Strengthening the voices of the unheard (2013) (0)
- A lab co-op helps young faculty members to thrive (2018) (0)
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