Regina Murphy
#175,356
Most Influential Person Now
American chemical engineer
Regina Murphy's AcademicInfluence.com Rankings
Regina Murphychemistry Degrees
Chemistry
#5478
World Rank
#6667
Historical Rank
Chemical Engineering
#777
World Rank
#798
Historical Rank

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Chemistry
Regina Murphy's Degrees
- Masters Chemical Engineering Stanford University
- PhD Chemical Engineering California Institute of Technology
Why Is Regina Murphy Influential?
(Suggest an Edit or Addition)According to Wikipedia, Regina Mary Murphy is an American chemical engineer. She is the Robert Byron Bird Department Chair in Chemical and Biological Engineering at the University of Wisconsin–Madison. In 2010, Murphy was elected a Fellow of the American Institute for Medical and Biological Engineering for "pioneering discoveries on protein aggregation in neurodegenerative disease."
Regina Murphy's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A mathematical model of the kinetics of beta-amyloid fibril growth from the denatured state. (2001) (248)
- Solvent effects on self-assembly of beta-amyloid peptide. (1995) (243)
- Correlation of beta-amyloid aggregate size and hydrophobicity with decreased bilayer fluidity of model membranes. (2000) (231)
- Peptide aggregation in neurodegenerative disease. (2002) (215)
- A Strategy for Designing Inhibitors of β-Amyloid Toxicity* (1996) (202)
- Structure-function relationships for inhibitors of beta-amyloid toxicity containing the recognition sequence KLVFF. (2001) (194)
- Recognition sequence design for peptidyl modulators of beta-amyloid aggregation and toxicity. (1999) (182)
- Kinetics of amyloid formation and membrane interaction with amyloidogenic proteins. (2007) (144)
- Examining polyglutamine peptide length: a connection between collapsed conformations and increased aggregation. (2009) (135)
- Kinetics of aggregation of synthetic β-amyloid peptide (1992) (132)
- Beta-amyloid peptide blocks the fast-inactivating K+ current in rat hippocampal neurons. (1996) (125)
- Affinity-Based Inhibition of β-Amyloid Toxicity† (2002) (108)
- Profile of Changes in Lipid Bilayer Structure Caused by β-Amyloid Peptide† (2001) (92)
- Probing the Kinetics of β-Amyloid Self-Association (2000) (88)
- Inhibition of insulin fibrillogenesis with targeted peptides (2006) (87)
- Light scattering analysis of fibril growth from the amino-terminal fragment beta(1-28) of beta-amyloid peptide. (1993) (86)
- Reconsidering the mechanism of polyglutamine peptide aggregation. (2007) (83)
- Characterization of the interaction of β-amyloid with transthyretin monomers and tetramers. (2010) (72)
- Kinetics of inhibition of β-amyloid aggregation by transthyretin (2006) (72)
- Kinetics of adsorption of β-amyloid peptide Aβ(1–40) to lipid bilayers (2003) (67)
- Serotonin receptor subtypes and the modulation of pain transmission. (1988) (67)
- Model discrimination and mechanistic interpretation of kinetic data in protein aggregation studies. (2009) (66)
- Effect of acid predissolution on fibril size and fibril flexibility of synthetic beta-amyloid peptide. (1994) (64)
- Size and structure of antigen-antibody complexes. Electron microscopy and light scattering studies. (1988) (61)
- Identification of beta-amyloid-binding sites on transthyretin. (2012) (56)
- Misbehaving proteins : protein (mis)folding, aggregation, and stability (2006) (56)
- Selective serotonin1A/1B agonists differentially affect spinal nociceptive reflexes (1990) (55)
- Design of peptidyl compounds that affect beta-amyloid aggregation: importance of surface tension and context. (2005) (51)
- Effect of beta-amyloid block of the fast-inactivating K+ channel on intracellular Ca2+ and excitability in a modeled neuron. (1996) (50)
- Transthyretin as both a sensor and a scavenger of β-amyloid oligomers. (2013) (50)
- Insights into the molecular mechanism of protein native-like aggregation upon glycation. (2013) (49)
- Protein Misfolding and Aggregation (2008) (48)
- Urea modulation of β‐amyloid fibril growth: Experimental studies and kinetic models (2004) (46)
- Quantitative analysis of protein synthesis inhibition by transferrin-toxin conjugates. (1994) (45)
- Phage display affords peptides that modulate beta-amyloid aggregation. (2006) (44)
- Solvent Effects on Self-Assembly of 1B-Amyloid Peptide (2005) (42)
- Coupled cellular trafficking and diffusional limitations in delivery of immunotoxins to multicell tumor spheroids. (1999) (39)
- Length-dependent aggregation of uninterrupted polyalanine peptides. (2011) (39)
- Transthyretin-derived peptides as β-amyloid inhibitors. (2014) (39)
- Aggregation state-dependent binding of beta-amyloid peptide to protein and lipid components of rat cortical homogenates. (1995) (37)
- Kinetics of inhibition of beta-amyloid aggregation by transthyretin. (2006) (36)
- Aggregation kinetics of interrupted polyglutamine peptides. (2011) (33)
- Recognition Sequence Design for Peptidyl Modulators of ‚-Amyloid Aggregation (1999) (33)
- Quasi-elastic light scattering of antigen-antibody complexes. (1988) (30)
- Evaluation of Nanoparticle Tracking for Characterization of Fibrillar Protein Aggregates. (2014) (28)
- Targeted Control of Kinetics of β-Amyloid Self-association by Surface Tension-modifying Peptides* (2003) (25)
- Asparagine Repeat Peptides: Aggregation Kinetics and Comparison with Glutamine Repeats. (2015) (25)
- Profile of changes in lipid bilayer structure caused by beta-amyloid peptide. (2001) (25)
- Influence of cellular trafficking on protein synthesis inhibition of immunotoxins directed against the transferrin receptor. (1995) (24)
- Elongation kinetics of polyglutamine peptide fibrils: a quartz crystal microbalance with dissipation study. (2012) (23)
- Probing the kinetics of beta-amyloid self-association. (2000) (23)
- Identification of a novel 5-HT1 binding site in rat spinal cord (1990) (21)
- Transthyretin variants with improved inhibition of β-amyloid aggregation. (2016) (21)
- Size and structure of antigen-antibody complexes: thermodynamic parameters. (1990) (21)
- Mechanism of Accelerated Assembly of β-Amyloid Filaments into Fibrils by KLVFFK6 (2004) (21)
- Kinetics of aggregation of synthetic beta-amyloid peptide. (1992) (21)
- Kinetics of adsorption of beta-amyloid peptide Abeta(1-40) to lipid bilayers. (2003) (20)
- Design of a pH-sensitive pore-forming peptide with improved performance. (2008) (20)
- Insights into the mechanism of cystatin C oligomer and amyloid formation and its interaction with β-amyloid (2017) (19)
- A Cyclic Peptide Mimic of the β-Amyloid Binding Domain on Transthyretin. (2015) (18)
- Affinity-based inhibition of beta-amyloid toxicity. (2002) (18)
- Synthesis and characterization of membrane-active GALA-OKT9 conjugates. (2001) (17)
- Functional change in the 5-HT presynaptic receptor in spinal cord of aged rats (1989) (17)
- Transthyretin Mimetics as Anti‐β‐Amyloid Agents: A Comparison of Peptide and Protein Approaches (2018) (16)
- Differential effects of substance P on serotonin-modulated spinal nociceptive reflexes (2005) (14)
- Structural characterization of apomyoglobin self-associated species in aqueous buffer and urea solution. (2006) (14)
- Cerebrospinal Fluid Proteins as Regulators of Beta-amyloid Aggregation and Toxicity. (2017) (14)
- Expression, purification, and characterization of human cystatin C monomers and oligomers. (2016) (13)
- Differential modification of Cys10 alters transthyretin's effect on beta-amyloid aggregation and toxicity. (2009) (13)
- Evaluation of nanoparticle tracking analysis for the detection of rod-shaped particles and protein aggregates. (2019) (12)
- Location trumps length: polyglutamine-mediated changes in folding and aggregation of a host protein. (2011) (12)
- Determining molecular weight distributions of antigen–antibody complex by quasi‐elastic light scattering (1991) (12)
- A mechanistic model to predict effects of cathepsin B and cystatin C on β-amyloid aggregation and degradation (2017) (11)
- Mechanism of accelerated assembly of beta-amyloid filaments into fibrils by KLVFFK(6). (2004) (11)
- Role of spinal serotonin1 receptor subtypes in thermally and mechanically elicited nociceptive reflexes (2005) (11)
- Kinetics of cellular trafficking and cytotoxicity of 9.2.27-gelonin immunotoxins targeted against the high-molecular-weight melanoma-associated antigen (1999) (10)
- Laser Light Scattering as an Indispensable Tool for Probing Protein Aggregation (2006) (10)
- Quantitative analysis of protein synthesis inhibition and recovery in CRM107 immunotoxin-treated HeLa cells. (1998) (10)
- Synthesis and disaggregation of asparagine repeat‐containing peptides (2014) (10)
- BMY 7378: Partial agonist at spinal cord 5-HT1A receptors (1990) (9)
- TANGO-Inspired Design of Anti-Amyloid Cyclic Peptides. (2016) (9)
- Retinol-Binding Protein Interferes with Transthyretin-Mediated β-Amyloid Aggregation Inhibition. (2018) (9)
- Membrane Remodeling and Stimulation of Aggregation Following α-Synuclein Adsorption to Phosphotidylserine Vesicles. (2021) (9)
- Selective 5-HT1B agonists identify the 5-HT autoreceptor in lumbar spinal cord of rat (1988) (8)
- Predicting Solvent and Aggregation Effects of Peptides Using Group Contribution Calculations (2006) (8)
- Templated assembly of the pH-sensitive membrane-lytic peptide GALA. (2004) (7)
- Protein Folding, Misfolding, Stability, and Aggregation (2006) (6)
- Biomaterials for Drug and Cell Delivery: Symposium Held November 29-December 1, 1993, Boston, Massachusetts, U.S.A (1994) (6)
- Necroptosis is associated with Rab27‐independent expulsion of extracellular vesicles containing RIPK3 and MLKL (2022) (4)
- When More Is Not Better: Expanded Polyglutamine Domains in Neurodegenerative Disease (2012) (4)
- Nanoparticle tracking analysis and statistical mixture distribution analysis to quantify nanoparticle-vesicle binding. (2022) (4)
- A strategy for generating polyglutamine 'length libraries' in model host proteins. (2008) (3)
- Staphylococcal protein A adsorption in neoplastic disease: analysis of physicochemical aspects. (1989) (3)
- Light Scattering Analysis of Fibril Growth from the Amino-terminal Fragment 13(1-28) of 13-Amyloid Peptide (2005) (3)
- Inhibition of Protein Synthesis in Small Cell Lung Cancer Cells Induced by the Diphtheria Toxin-related Fusion Protein DAB 389 GRP ' (2006) (3)
- SIZE AND STRUCTURE OF ANTIGEN-ANTIBODY COMPLEXES (2005) (3)
- ROSETTA-informed design of structurally stabilized cyclic anti-amyloid peptides. (2019) (3)
- Kinetic analysis of aggregation data. (2013) (2)
- Nanoparticle Tracking for Protein Aggregation Research. (2018) (2)
- Retinol binding protein IV purified from Escherichia coli using intein-mediated cleavage as a suitable replacement for serum sources. (2019) (1)
- f3-Amyloid Peptide Blocks the Fast-inactivating K+ Current in Rat Hippocampal Neurons (2005) (0)
- Design and screening of M13 phage libraries directed against beta amyloid (2003) (0)
- Book Review of Protein Folding, Misfolding and Aggregation: Classical Themes and Novel Approaches Protein Folding, Misfolding and Aggregation: Classical Themes and Novel Approaches. Edited by Victor Muñoz (University of Maryland, College Park, USA and Center for Biological Investigations, Madrid, S (2008) (0)
- Insights into the molecular mechanism of protein native-like aggregation upon methylglyoxal glycation (2011) (0)
- Kinetics of Peptide Aggregation in Neurodegenerative Disease (2009) (0)
- An in vitro model for vitamin A transport across the human blood-brain barrier (2023) (0)
- Quantitative autoradiographic mapping of a novel serotonin receptor-5-HT1S. (1992) (0)
- Q&A: repeat-containing proteins (2015) (0)
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