Reina Bendayan

Reina Bendayan's AcademicInfluence.com Rankings

Reina Bendayan

Medical

#3716

World Rank

#4219

Historical Rank

Pharmacology

#484

World Rank

#543

Historical Rank

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Medical

Why Is Reina Bendayan Influential?

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According to Wikipedia, Reina Bendayan is a Canadian pharmacologist. She is a professor in the Department of Pharmaceutical Sciences in the Leslie Dan Faculty of Pharmacy at the University of Toronto and Career Scientist at the Ontario HIV Treatment Network.

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Reina Bendayan's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles. (2007) (503)
Nanotechnological advances for the delivery of CNS therapeutics. (2012) (411)
A Mechanistic Study of Enhanced Doxorubicin Uptake and Retention in Multidrug Resistant Breast Cancer Cells Using a Polymer-Lipid Hybrid Nanoparticle System (2006) (339)
Drug transporters in the central nervous system: brain barriers and brain parenchyma considerations. (2001) (327)
A New Polymer–Lipid Hybrid Nanoparticle System Increases Cytotoxicity of Doxorubicin Against Multidrug-Resistant Human Breast Cancer Cells (2006) (295)
Multidrug Resistance-Associated Proteins: Expression and Function in the Central Nervous System (2006) (281)
The complexities of antiretroviral drug-drug interactions: role of ABC and SLC transporters. (2010) (220)
Nanotechnology applications for improved delivery of antiretroviral drugs to the brain. (2010) (199)
In Situ Localization of P-glycoprotein (ABCB1) in Human and Rat Brain (2006) (193)
Functional expression and localization of P‐glycoprotein at the blood brain barrier (2002) (188)
Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new polymer-lipid hybrid nanoparticles (PLN) for enhanced treatment of multidrug-resistant breast cancer. (2006) (181)
Development of solid lipid nanoparticles containing ionically complexed chemotherapeutic drugs and chemosensitizers. (2004) (174)
Solid Lipid Nanoparticles Enhance the Delivery of the HIV Protease Inhibitor, Atazanavir, by a Human Brain Endothelial Cell Line (2008) (166)
HIV-1 Viral Envelope Glycoprotein gp120 Triggers an Inflammatory Response in Cultured Rat Astrocytes and Regulates the Functional Expression of P-Glycoprotein (2006) (148)
Functional Expression and Localization of P-glycoprotein in the Central Nervous System: Relevance to the Pathogenesis and Treatment of Neurological Disorders (2004) (119)
Up‐regulation of P‐glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line (2009) (113)
Design and characterization of HER-2-targeted gold nanoparticles for enhanced X-radiation treatment of locally advanced breast cancer. (2010) (107)
Medicinal and recreational marijuana use by patients infected with HIV. (2004) (106)
Cellular localization and functional expression of P‐glycoprotein in rat astrocyte cultures (2004) (102)
In vivo evaluation of a new polymer-lipid hybrid nanoparticle (PLN) formulation of doxorubicin in a murine solid tumor model. (2007) (100)
Clinical Pharmacokinetics of Non-Opiate Abused Drugs (1989) (97)
HIV‐1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein‐1 (Mrp1) in glial cells (2008) (96)
A study of doxorubicin loading onto and release from sulfopropyl dextran ion-exchange microspheres. (2001) (93)
Functional Expression of the Multidrug Resistance Protein 1 in Microglia (2003) (93)
Regulation of ABC membrane transporters in glial cells: Relevance to the pharmacotherapy of brain HIV‐1 infection (2008) (93)
Functional expression of P-glycoprotein in rat brain microglia. (2001) (92)
Acute effects of focused ultrasound-induced increases in blood-brain barrier permeability on rat microvascular transcriptome (2017) (83)
Multidrug Resistance Protein (MRP) 4- and MRP 5-Mediated Efflux of 9-(2-Phosphonylmethoxyethyl)adenine by Microglia (2004) (82)
Use of complementary and alternative medicine by HIV-infected outpatients in Ontario, Canada. (2003) (79)
Expression of ATP-Binding Cassette Membrane Transporters in Rodent and Human Sertoli Cells: Relevance to the Permeability of Antiretroviral Therapy at the Blood-Testis Barrier (2012) (75)
Regulation of P‐glycoprotein by orphan nuclear receptors in human brain microvessel endothelial cells (2011) (72)
Regulation of Multidrug Resistance Protein 1 by Tumor Necrosis Factor α in Cultured Glial Cells: Involvement of Nuclear Factor-κB and c-Jun N-Terminal Kinase Signaling Pathways (2010) (68)
Expression of the ATP-binding Cassette Membrane Transporter, ABCG2, in Human and Rodent Brain Microvessel Endothelial and Glial Cell Culture Systems (2007) (68)
1α,25‐Dihydroxyvitamin D3‐liganded vitamin D receptor increases expression and transport activity of P‐glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells (2012) (67)
Role of Drug Efflux and Uptake Transporters in Atazanavir Intestinal Permeability and Drug-Drug Interactions (2013) (66)
Differential Role of Organic Anion-Transporting Polypeptides in Estrone-3-Sulphate Uptake by Breast Epithelial Cells and Breast Cancer Cells (2012) (58)
Regulation of Breast Cancer Resistant Protein by Peroxisome Proliferator-Activated Receptor α in Human Brain Microvessel Endothelial Cells (2012) (56)
Role of P-Glycoprotein in the Distribution of the HIV Protease Inhibitor Atazanavir in the Brain and Male Genital Tract (2013) (54)
In vitro investigation of ionic polysaccharide microspheres for simultaneous delivery of chemosensitizer and antineoplastic agent to multidrug-resistant cells. (1999) (53)
pH Dependence of Organic Anion-Transporting Polypeptide 2B1 in Caco-2 Cells: Potential Role in Antiretroviral Drug Oral Bioavailability and Drug–Drug Interactions (2010) (53)
Involvement of P-Glycoprotein in the Transport of Saquinavir and Indinavir in Rat Brain Microvessel Endothelial and Microglia Cell Lines (2004) (51)
Delivery of an anticancer drug and a chemosensitizer to murine breast sarcoma by intratumoral injection of sulfopropyl dextran microspheres (2003) (48)
Glutathione Stability in Whole Blood: Effects of Various Deproteinizing Acids (2001) (48)
Antiretroviral drug transporters and metabolic enzymes in human testicular tissue: potential contribution to HIV-1 sanctuary site. (2016) (45)
Renal Drug Transport: A Review (1996) (43)
Induction of P-Glycoprotein by Antiretroviral Drugs in Human Brain Microvessel Endothelial Cells (2013) (42)
Immune tolerance properties of the testicular tissue as a viral sanctuary site in ART-treated HIV-infected adults (2016) (42)
In vivo induction of P‐glycoprotein expression at the mouse blood–brain barrier: an intracerebral microdialysis study (2013) (41)
Role and modulation of drug transporters in HIV-1 therapy. (2016) (40)
HIV-1 Alters Intestinal Expression of Drug Transporters and Metabolic Enzymes: Implications for Antiretroviral Drug Disposition (2016) (40)
Polypharmacy in HIV: impact of data source and gender on reported drug utilization. (2004) (39)
Medication use patterns in HIV-positive patients. (1993) (39)
Multidrug resistance protein 1-mediated transport of saquinavir by microglia (2004) (38)
Xenobiotic Nuclear Receptors Pregnane X Receptor and Constitutive Androstane Receptor Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier (2017) (37)
Regulation of P‐glycoprotein by human immunodeficiency virus‐1 in primary cultures of human fetal astrocytes (2011) (36)
Localization of P-glycoprotein at the nuclear envelope of rat brain cells. (2007) (35)
A novel zidovudine uptake system in microglia. (2001) (32)
Role of anti-inflammatory compounds in human immunodeficiency virus-1 glycoprotein120-mediated brain inflammation (2014) (32)
Functional expression of drug transporters in glial cells: potential role on drug delivery to the CNS. (2014) (32)
Regulation of Reduced Folate Carrier (RFC) by Vitamin D Receptor at the Blood-Brain Barrier. (2017) (32)
Raltegravir Permeability across Blood-Tissue Barriers and the Potential Role of Drug Efflux Transporters (2015) (32)
A Na(+)-dependent nucleoside transporter in microglia. (2000) (31)
In vitro toxicity to breast cancer cells of microsphere-delivered mitomycin C and its combination with doxorubicin. (2006) (31)
Role of nuclear receptors in the regulation of drug transporters in the brain. (2013) (31)
Role of P-glycoprotein in the renal transport of dideoxynucleoside analog drugs. (1999) (31)
Triton‐X‐100‐modified polymer and microspheres for reversal of multidrug resistance (2001) (30)
Synthesis and characterization of surface-hydrophobic ion-exchange microspheres and the effect of coating on drug release rate. (2000) (29)
Expression, activity and regulation of CYP3A in human and rodent brain. (2008) (29)
Peroxisome proliferator-activated receptor-gamma: potential molecular therapeutic target for HIV-1-associated brain inflammation (2017) (28)
Expression of Membrane Drug Efflux Transporters in the Sigmoid Colon of HIV‐Infected and Uninfected Men (2013) (27)
Upregulation of reduced folate carrier by vitamin D enhances brain folate uptake in mice lacking folate receptor alpha (2019) (26)
Peroxisome Proliferator-Activated Receptor-gamma agonists exhibit anti-inflammatory and antiviral effects in an EcoHIV mouse model (2019) (25)
Two‐Step Targeted Hybrid Nanoconstructs Increase Brain Penetration and Efficacy of the Therapeutic Antibody Trastuzumab against Brain Metastasis of HER2‐Positive Breast Cancer (2018) (25)
Estrone-3-Sulphate, a Potential Novel Ligand for Targeting Breast Cancers (2013) (22)
Expression of membrane transporters and metabolic enzymes involved in estrone-3-sulphate disposition in human breast tumour tissues (2014) (21)
Uptake properties of lamivudine (3TC) by a continuous renal epithelial cell line. (2001) (21)
Interactions between phytochemical components of Sutherlandia frutescens and the antiretroviral, atazanavir in vitro: implications for absorption and metabolism. (2012) (21)
Expression, Activity and Regulation of CYP3A in Human and Rodent Brain (2008) (21)
In vivo and ex vivo regulation of breast cancer resistant protein (Bcrp) by peroxisome proliferator‐activated receptor alpha (Pparα) at the blood–brain barrier (2015) (20)
Inhibition kinetics of cationic drugs on N'-methylnicotinamide uptake by brush border membrane vesicles from the dog kidney cortex. (1990) (19)
Characterization of cimetidine transport in LLCPK1 cells. (1994) (18)
Longitudinal trends in antiretroviral use in a cohort of men and women in Ontario, Canada. (2006) (18)
“HIV isn't me…”: HIV+ adolescents' experiences in a positive context of support and treatment (2011) (18)
Interaction of 3′‐Azido‐3′‐Deoxythymidine With the Organic Base Transporter in a Cultured Renal Epithelium (1995) (18)
Drug Transporters At Brain Barriers (2013) (18)
Effect of cimetidine and ranitidine on the hepatic and renal elimination of nicotine in humans (2004) (17)
Expression of ATP-binding cassette membrane transporters in a HIV-1 transgenic rat model. (2014) (17)
Solid Lipid Nanoparticles for Anti-Tumor Drug Delivery (2006) (17)
Drug transporters at brain barriers: expression and regulation by neurological disorders. (2012) (16)
In Vitro and In Situ Evaluation of pH-Dependence of Atazanavir Intestinal Permeability and Interactions with Acid-Reducing Agents (2014) (16)
Clinical Implications of Folate Transport in the Central Nervous System. (2020) (16)
Role of CNS transporters in the pharmacotherapy of HIV-1 associated neurological disorders. (2014) (14)
Multidrug Resistance in Solid Tumor and Its Reversal (2009) (14)
Molecular and functional characterization of P-glycoprotein in vitro. (2011) (13)
Gentamicin uptake by LLCPK1 cells: effect of intracellular and extracellular pH changes. (1998) (11)
Digoxin pharmacokinetics and dosage requirements in pediatric patients. (1983) (10)
Characterization of a Microsphere Formulation Containing Glucose Oxidase and its In Vivo Efficacy in a Murine Solid Tumor Model (2009) (10)
Drug Transport in the Brain (2006) (10)
Potential pharmacological approaches for the treatment of HIV-1 associated neurocognitive disorders (2020) (9)
Selective peroxisome proliferator‐activated receptor‐gamma modulator, INT131 exhibits anti‐inflammatory effects in an EcoHIV mouse model (2019) (8)
Efflux transporters in cancer resistance: Molecular and functional characterization of P-glycoprotein (2020) (8)
Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment (2013) (8)
Transporters in Drug Development: International Transporter Consortium Update on Emerging Transporters of Clinical Importance (2022) (8)
Interaction of dipyridamole, a nucleoside transport inhibitor, with the renal transport of organic cations by LLCPK1 cells. (1997) (7)
(125)I-Labelled 2-Iodoestrone-3-sulfate: synthesis, characterization and OATP mediated transport studies in hormone dependent and independent breast cancer cells. (2015) (7)
Nuclear respiratory factor 1 (NRF‐1) upregulates the expression and function of reduced folate carrier (RFC) at the blood‐brain barrier (2020) (7)
Interaction between dolutegravir and folate transporters and receptor in human and rodent placenta (2021) (5)
Pharmacokinetic interaction between zidovudine and trimethoprim/sulphamethoxazole in HIV-1 infected children. (2000) (5)
Impact of in-utero antiretroviral drug exposure on expression of membrane-associated transporters in mouse placenta and fetal brain (2021) (5)
Functional Expression of the Multidrug Resistance Protein 1 (MRP1) in Microglia. (2003) (5)
HIV-1 Sanctuary Sites—the Role of Membrane-Associated Drug Transporters and Drug Metabolic Enzymes (2020) (5)
Drug efflux transporters and metabolic enzymes in human circulating and testicular T-cell subsets: relevance to HIV pharmacotherapy. (2020) (5)
Renal Drug Transport and Drug-Drug Interactions (2002) (4)
Regulation of Multidrug Resistance Protein 1 by Tumor Necrosis Factor (cid:1) in Cultured Glial Cells: Involvement of Nuclear Factor- (cid:2) B and c-Jun N-Terminal Kinase Signaling Pathways (2010) (4)
Aryl hydrocarbon receptor upregulates IL-1β expression in hCMEC/D3 human cerebral microvascular endothelial cells after TCDD exposure. (2017) (4)
MRP4‐ and MRP5‐mediated efflux of 9‐(2‐phosphonylmethoxyethyl)adenine (PMEA) by microglia (2004) (3)
Antiretroviral Drug Transporters and Metabolic Enzymes in Circulating Monocytes and Monocyte-Derived Macrophages of ART-Treated People Living With HIV and HIV-Uninfected Individuals (2021) (3)
Regulation of ABC Drug Efflux Transporters in Human T-Cells Exposed to an HIV Pseudotype (2021) (3)
New Drug Interactions with Zidovudine (1997) (3)
Novel localization of folate transport systems in the murine central nervous system (2022) (3)
The journey to AAPS 2020: a reflection from strategic planning to PharmSci 360 (2018) (3)
Xenobiotic Nuclear Receptors PXR and CAR Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier (2017) (2)
Role of anti-inflammatory compounds in human immunodeficiency virus-1 glycoprotein120-mediated brain inflammation (2014) (2)
Regulation of Multidrug Resistance Protein 1 (Mrp1) by Tumor Necrosis Factor Alpha (TNF-α) in Cultured Glial Cells: Involvement of Nuclear Factor-κB (NF-κB) and c-Jun N-terminal Kinase (JNK) Signaling Pathways (2010) (2)
Interaction of dipyridamole, a nucleoside transport inhibitor, with the renal transport of organic cations by LLCPK1 cells (1997) (2)
Differential effects of antiretroviral drug toxicity in male versus female children who are HIV-exposed but uninfected. (2020) (2)
Lack of effect of cimetidine on cigarette smoking (2004) (2)
Role of Drug Efflux and Uptake Transporters in Atazanavir Intestinal Permeability and Drug-Drug Interactions (2012) (1)
Pharmacokinetic considerations to optimize clinical outcomes for COVID-19 drugs (2022) (1)
MDR reversal for effective chemotherapy in breast cancer (2020) (1)
Functional expression of P-glycoprotein in a rat brain endothelial cell line (2001) (1)
Peroxisome proliferator-activated receptor-gamma: potential molecular therapeutic target for HIV-1-associated brain inflammation (2017) (1)
Localization of the Folate Transport Systems in the Murine Central Nervous System (2021) (1)
Microvessel Endothelial Cells Antiretroviral Drugs in Human Brain Induction of P-Glycoprotein by (2014) (0)
Reviewer Acknowledgments (2009) (0)
OATP mediated transport studies in hormone dependent and independent breast cancer cells (2015) (0)
Differential Role of OATPs in Estrone-3-Sulphate Uptake by Breast Epithelial Cells and Breast Cancer Cells i (2012) (0)
The Journey to AAPS 2020: a Reflection from Strategic Planning to PharmSci 360 (2018) (0)
Furosemide and extracellular acidification enhance gentamicin “g” uptake by llcpk1 monolayer cells (1996) (0)
Functional expression of P-glycoprotein in primary rat astrocyte cultures and an immortalized rat astrocyte cell line (2002) (0)
The journey to AAPS 2020: a reflection from strategic planning to PharmSci 360 (2018) (0)
Abstract 3929: Estrone-3-sulphate, a potential novel ligand for targeting breast cancers. (2013) (0)
Peroxisome Proliferator-Activated Receptor-gamma agonists exhibit anti-inflammatory and antiviral effects in an EcoHIV mouse model (2019) (0)
The Journey to AAPS 2020: a Reflection from Strategic Planning to PharmSci 360 (2018) (0)
Protected rituximab aims at brain metastases (2019) (0)
A Na 1-Dependent Nucleoside Transporter in Microglia 1 (1999) (0)
Potential pharmacological approaches for the treatment of HIV-1 associated neurocognitive disorders (2020) (0)
Uptake properties of zidovudine (ZDV) by an HIV‐I target brain parenchyma cell line (1999) (0)
Human Immunodeficiency Viral Disease (2008) (0)
The Journey to AAPS 2020: a Reflection from Strategic Planning to PharmSci 360 (2018) (0)
Is P‐glycoprotein (P‐gp) involved in the renal tubular transport of nucleoside analog drugs (NADs)? (1999) (0)
SARS-CoV-2 infection dysregulates the expression of clinically relevant drug metabolizing enzymes in Vero E6 cells and membrane transporters in human lung tissues (2023) (0)
In vitro interaction of 3' azido 3' deoxythymidine with the uptake of N1-methylnicotinamide (1990) (0)
The Journey to AAPS 2020: a Reflection from Strategic Planning to PharmSci 360 (2018) (0)
In Vitro and In Situ Evaluation of pH-Dependence of Atazanavir Intestinal Permeability and Interactions with Acid-Reducing Agents (2014) (0)
2-Iodoestrone-3-sulfate: Synthesis, radioiodination and OATP mediated transport in hormone dependent and independent breast cancer cells (2014) (0)
Characterization of uridine transport properties by a rat intestinal epithelial cell line (IEC‐6) (1999) (0)
Raltegravir Permeability across Blood-Tissue Barriers : Potential Role of Drug Efflux 1 Transporters (2015) (0)
Antiretroviral drugs efavirenz, dolutegravir and bictegravir dysregulate blood-brain barrier integrity and function (2023) (0)
Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment (2013) (0)
Role of P-glycoprotein in the distribution of the HIV-protease inhibitor, atazanavir, in the (2013) (0)
Abstract 377: Organic Anion Transporting Polypeptides (OATPs): A potential new molecular target for imaging/therapy of hormone dependent breast cancers (2012) (0)
Folate Transporters Are Found Throughout the Colon of Humans and Their mRNA Expression Appears to Be Unaffected by Low Dose Folic Acid Supplementation (2021) (0)
Transport properties of thymidine by a rat microglia cell line (1999) (0)

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Other Resources About Reina Bendayan

en.wikipedia.org

What Schools Are Affiliated With Reina Bendayan?

Reina Bendayan is affiliated with the following schools:

University of Toronto