Rémi Quirion
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Canadian researcher
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Neuroscience
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Biochemistry
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Biology
Rémi Quirion's Degrees
- PhD Neuroscience McGill University
- Masters Neuroscience McGill University
Why Is Rémi Quirion Influential?
(Suggest an Edit or Addition)According to Wikipedia, Rémi Quirion, is a Canadian scientist. He is the first Chief Scientist of Quebec. Born in Lac-Drolet, Quebec, Quirion received a Ph.D. from Université de Sherbrooke in 1980. He was a Professor of Psychiatry at McGill University and Scientific Director of the Douglas Hospital Research Centre.
Rémi Quirion's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. (1998) (879)
- International Union of Pharmacology. XXXII. The Mammalian Calcitonin Gene-Related Peptides, Adrenomedullin, Amylin, and Calcitonin Receptors (2002) (748)
- A proposal for the classification of sigma binding sites. (1992) (706)
- Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease. (1995) (613)
- Autoradiographic localization of angiotensin II receptors in rat brain. (1984) (568)
- Alzheimer’s disease and the basal forebrain cholinergic system: relations to β-amyloid peptides, cognition, and treatment strategies (2002) (561)
- Neuroanatomical Localization, Pharmacological Characterization and Functions of CGRP, Related Peptides and Their Receptors (1997) (493)
- Neuropeptide Y and neuropeptide Y receptor subtypes in brain and peripheral tissues (1992) (376)
- The ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by β‐amyloid (2000) (350)
- Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. (2005) (349)
- Decreased expression of the embryonic form of the neural cell adhesion molecule in schizophrenic brains. (1995) (334)
- hCGRP8-37, a calcitonin gene-related peptide antagonist revealing calcitonin gene-related peptide receptor heterogeneity in brain and periphery. (1990) (333)
- Comparative Alterations of Nicotinic and Muscarinic Binding Sites in Alzheimer's and Parkinson's Diseases (1992) (330)
- Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity. (1997) (330)
- Differential Alteration of Various Cholinergic Markers in Cortical and Subcortical Regions of Human Brain in Alzheimer's Disease (1988) (325)
- The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y (2002) (324)
- Psychosis pathways converge via D2High dopamine receptors (2006) (322)
- Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression. (2000) (313)
- Say NO to Alzheimer’s disease: the putative links between nitric oxide and dementia of the Alzheimer’s type (2001) (313)
- Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide‐related toxicity in cultured hippocampal neurons (2000) (307)
- Neuroprotective effects of resveratrol against β‐amyloid‐induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C (2004) (306)
- A comparison of the anatomical distribution of substance P and substance P receptors in the rat central nervous system (1984) (303)
- The effects of chronic antidepressant treatment in an animal model of anxiety (2004) (301)
- Neuroprotective effects of green and black teas and their catechin gallate esters against β‐amyloid‐induced toxicity (2006) (280)
- Atrial natriuretic factor (ANF) binding sites in brain and related structures (1984) (278)
- Psychiatry as a clinical neuroscience discipline. (2005) (273)
- Neuroprotective action of resveratrol. (2015) (273)
- Chemokines and chemokine receptors in the CNS: a possible role in neuroinflammation and patterning. (1999) (271)
- Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies. (2002) (268)
- Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage. (1999) (267)
- Classification and nomenclature of phencyclidine and sigma receptor sites (1987) (262)
- Cytokine indices in Alzheimer's temporal cortex: no changes in mature IL-1β or IL-1RA but increases in the associated acute phase proteins IL-6, α2-macroglobulin and C-reactive protein (1993) (257)
- Circadian rhythms of melatonin and cortisol in aging (1989) (251)
- Distinct electrophysiological properties of glutamatergic, cholinergic and GABAergic rat septohippocampal neurons: novel implications for hippocampal rhythmicity (2003) (242)
- Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype. (1999) (241)
- Structure-activity profile of calcitonin gene-related peptide in peripheral and brain tissues. Evidence for receptor multiplicity. (1989) (240)
- Phencyclidine (angel dust)/sigma "opiate" receptor: visualization by tritium-sensitive film. (1981) (238)
- Autoradiographic distribution of substance P receptors in rat central nervous system (1983) (229)
- Comparative signaling pathways of insulin‐like growth factor‐1 and brain‐derived neurotrophic factor in hippocampal neurons and the role of the PI3 kinase pathway in cell survival (2004) (217)
- Nucleus basalis neuronal loss, neuritic plaques and choline acetyltransferase activity in advanced Alzheimer's disease (1986) (214)
- Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completers. (2009) (212)
- Facilitation of acetylcholine release and cognitive performance by an M(2)-muscarinic receptor antagonist in aged memory-impaired (1995) (210)
- Comparative characterization and autoradiographic distribution of neuropeptide Y receptor subtypes in the rat brain (1993) (207)
- β-Amyloid peptides as direct cholinergic neuromodulators: a missing link? (1998) (202)
- Quantitative autoradiographic localization of [125I]insulin‐like growth factor I, [125I]insulin‐like growth factor II, and [125I]insulin receptor binding sites in developing and adult rat brain (1993) (201)
- Species differences in the expression and distribution of the neuropeptide Y Y1, Y2, Y4, and Y5 receptors in rodents, guinea pig, and primates brains (1998) (197)
- Natural extracts as possible protective agents of brain aging (2002) (196)
- Rediscovering an old friend, IGF-I: potential use in the treatment of neurodegenerative diseases. (1997) (195)
- Interleukin-2 as a neuroregulatory cytokine (1995) (195)
- Decreased binding of dopamine D3 receptors in limbic subregions after neonatal bilateral lesion of rat hippocampus (1996) (189)
- Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus (2002) (187)
- The Neuropeptide Y (NPY) Y1 Receptor Subtype Mediates NPY-induced Antidepressant-like Activity in the Mouse Forced Swimming Test (2002) (186)
- Comparative localization of neurotensin receptors on nigrostriatal and mesolimbic dopaminergic terminals (1985) (186)
- A possible role of neuropeptide Y in depression and stress (2010) (186)
- Reduction in p140-TrkA Receptor Protein within the Nucleus Basalis and Cortex in Alzheimer's Disease (1997) (181)
- Characterization of CGRP1 and CGRP2 Receptor Subtypes a (1992) (179)
- The Ginkgo biloba Extract (EGb 761) Protects and Rescues Hippocampal Cells Against Nitric Oxide‐Induced Toxicity (2000) (178)
- Apoptosis-inducing factor: A matter of neuron life and death (2007) (177)
- Localization of interleukin-2 immunoreactivity and interleukin-2 receptors in the rat brain: interaction with the cholinergic system (1989) (177)
- cAMP Response Element-Binding Protein (CREB): A Possible Signaling Molecule Link in the Pathophysiology of Schizophrenia (2018) (174)
- A comparison of the effects of diazepam versus several typical and atypical anti-depressant drugs in an animal model of anxiety (2004) (168)
- Autoradiographic distribution of [3H]neurotensin receptors in rat brain: Visualization by tritium-sensitive film (1982) (167)
- Alterations in hippocampal network oscillations and theta–gamma coupling arise before Aβ overproduction in a mouse model of Alzheimer's disease (2013) (166)
- Oxytocin-Induced Analgesia and Scratching Are Mediated by the Vasopressin-1A Receptor in the Mouse (2010) (165)
- Neuropeptide Y receptors in rat brain: Autoradiographic localization (1986) (165)
- Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene. (2005) (165)
- The molecular pharmacology of CGRP and related peptide receptor subtypes. (2000) (163)
- Insulin-like Growth Factor-1-induced Phosphorylation of the Forkhead Family Transcription Factor FKHRL1 Is Mediated by Akt Kinase in PC12 Cells* (2000) (162)
- Molecular basis of programmed cell death involved in neurodegeneration (2005) (161)
- Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons. (2002) (161)
- Quantitative autoradiographic distribution of multiple neurokinin binding sites in rat spinal cord (1990) (160)
- Amyloid β‐Peptide Inhibits High‐Affinity Choline Uptake and Acetylcholine Release in Rat Hippocampal Slices (1998) (160)
- Autoradiographic distribution of [125I]Leu31,Pro34]PYY and [125I]PYY3–36 binding sites in the rat brain evaluated with two newly developed Y1 and Y2 receptor radioligands (1996) (159)
- Substance P and Neurokinins (1987) (159)
- Chronic morphine exposure increases the phosphorylation of MAP kinases and the transcription factor CREB in dorsal root ganglion neurons: an in vitro and in vivo study (2001) (158)
- Interactions between neurotensin and dopamine in the brain: An overview (1983) (155)
- Characterization and distribution of receptors for the atrial natriuretic peptides in mammalian brain. (1986) (154)
- Effects of aging on nicotinic and muscarinic autoreceptor function in the rat brain: relationship to presynaptic cholinergic markers and binding sites (1990) (153)
- Expression and Characterization of the Neuropeptide Y Y5 Receptor Subtype in the Rat Brain (1998) (151)
- Multiple receptors for neuropeptide Y in the hippocampus: putative roles in seizures and cognition (1999) (151)
- Insulin-like growth factor-1 (somatomedin-C) receptors in the rat brain: distribution and interaction with the hippocampal cholinergic system (1989) (147)
- Multiple tachykinin receptors (1985) (138)
- Multiple neurokinin receptors: Recent developments (1988) (135)
- The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid. (2000) (135)
- Neuropeptide Y (NPY) and depression: from animal studies to the human condition. (2002) (134)
- [3H]1,3-di(2-tolyl)guanidine and [3H](+)pentazocine binding sites in the rat brain: Autoradiographic visualization of the putative sigma1 and sigma2 receptor subtypes (1997) (132)
- The pharmacology of Adrenomedullin 2/Intermedin (2012) (132)
- Noxious thermal and chemical stimulation induce increases in 3H-phorbol 12,13-dibutyrate binding in spinal cord dorsal horn as well as persistent pain and hyperalgesia, which is reduced by inhibition of protein kinase C (1995) (131)
- Pharmacological characterization of human NPFF(1) and NPFF(2) receptors expressed in CHO cells by using NPY Y(1) receptor antagonists. (2002) (130)
- The ERK/MAPK pathway, as a target for the treatment of neuropathic pain (2005) (130)
- Blockade and reversal of spinal morphine tolerance by peptide and non‐peptide calcitonin gene‐related peptide receptor antagonists (2000) (127)
- The chemokine interleukin‐8 acutely reduces Ca2+ currents in identified cholinergic septal neurons expressing CXCR1 and CXCR2 receptor mRNAs (2001) (127)
- Calcitonin gene-related peptide in viscerosensitive response to colorectal distension in rats. (1997) (127)
- A microdialysis profile of β-endorphin and catecholamines in the rat nucleus accumbens following alcohol administration (2003) (125)
- Beta-amyloid-related peptides inhibit potassium-evoked acetylcholine release from rat hippocampal slices (1996) (125)
- Dopamine D1, receptor ligands modulate cognitive performance and hippocampal acetylcholine release in memory-impaired aged rats (1995) (124)
- BIIE0246, a potent and highly selective non‐peptide neuropeptide Y Y2 receptor antagonist (2000) (123)
- Characterization of neuropeptide Y binding sites in rat brain membrane preparations using [125I][Leu31,Pro34]peptide YY and [125I]peptide YY3-36 as selective Y1 and Y2 radioligands. (1995) (123)
- Characterization of N‐[3H]Methylcarbamylcholine Binding Sites and Effect of N‐Methylcarbamylcholine on Acetylcholine Release in Rat Brain (1988) (123)
- Neuropeptide Y (NPY) Y2 receptors mediate behaviour in two animal models of anxiety: evidence from Y2 receptor knockout mice (2003) (123)
- Localization and modulation of calcitonin gene-related peptide-receptor component protein-immunoreactive cells in the rat central and peripheral nervous systems (2003) (122)
- Characterization and visualization of cholecystokinin receptors in rat brain using [3H]pentagastrin (1983) (122)
- Distribution and levels of [125I]IGF-I, [125I]IGF-II and [125I]insulin receptor binding sites in the hippocampus of aged memory-unimpaired and -impaired rats (1997) (121)
- Enhanced Amphetamine Sensitivity and Increased Expression of Dopamine D2 Receptors in Postpubertal Rats after Neonatal Excitotoxic Lesions of the Medial Prefrontal Cortex (1996) (121)
- Ontogeny of substance P receptor binding sites in rat brain (1986) (120)
- Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice (2009) (119)
- Inflammatory mediators modulating the transient receptor potential vanilloid 1 receptor: therapeutic targets to treat inflammatory and neuropathic pain (2007) (118)
- Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway. (2000) (118)
- Localization and characterization of brain somatostatin receptors as studied with somatostatin-14 and somatostatin-28 receptor radioautography (1985) (117)
- Neuropeptide Y: localization in the central nervous system and neuroendocrine functions (1990) (115)
- Visualization of neurokinin-3 receptor sites in rat brain using the highly selective ligand [3H]senktide (1990) (114)
- Autoradiographic localization of mu, delta and kappa opioid receptor binding sites in rat and guinea pig spinal cord (1985) (112)
- Differential distribution of neuropeptide Y1 and Y2 receptors in the rat brain. (1990) (112)
- Interleukin‐2 Modulates Evoked Release of [3H]Dopamine in Rat Cultured Mesencephalic Cells (1993) (112)
- Effect of Chronic Nicotine Treatment on Nicotinic Autoreceptor Function and N‐[3H]Methylcarbamylcholine Binding Sites in the Rat Brain (1989) (112)
- Distribution of mu, delta, and kappa opiate receptor types in the forebrain and midbrain of pigeons (1989) (112)
- Immunoautoradiographic localization of interleukin 2-like immunoreactivity and interleukin 2 receptors (Tac antigen-like immunoreactivity) in the rat brain (1991) (111)
- Modulation of hippocampal acetylcholine release: a potent central action of interleukin-2 (1993) (110)
- A calcitonin gene-related peptide receptor antagonist prevents the development of tolerance to spinal morphine analgesia (1996) (109)
- Comparative ontogenic profile of cholinergic markers, including nicotinic and muscarinic receptors, in the rat brain (1996) (108)
- Morphological reorganization after repeated corticosterone administration in the hippocampus, nucleus accumbens and amygdala in the rat (2009) (106)
- NCAM‐180 knockout mice display increased lateral ventricle size and reduced prepulse inhibition of startle (1998) (106)
- Selective Mediation of Nerve Injury-Induced Tactile Hypersensitivity by Neuropeptide Y (2002) (105)
- Binding sites for [3H]AF-DX 116 and effect of AF-DX 116 on endogenous acetylcholine release from rat brain slices (1989) (105)
- Differential neurobehavioral effects of neurotensin and structural analogues (1981) (103)
- Neurotransmitter and Receptor Deficits in Senile Dementia of the Alzheimer Type (1986) (102)
- Specific Plasma Membrane Binding Sites for Polyphenols, Including Resveratrol, in the Rat Brain (2006) (102)
- An in vivo profile of β-endorphin release in the arcuate nucleus and nucleus accumbens following exposure to stress or alcohol (2004) (102)
- A microdialysis profile of dynorphin A(1-8) release in the rat nucleus accumbens following alcohol administration. (2006) (101)
- Estrogen effects on object memory and cholinergic receptors in young and old female mice (2002) (101)
- THE STIMULATORY EFFECTS OF NEUROTENSIN AND RELATED PEPTIDES IN RAT STOMACH STRIPS AND GUINEA‐PIG ATRIA (1980) (101)
- Comparative effects of cyclo‐oxygenase and nitric oxide synthase inhibition on the development and reversal of spinal opioid tolerance (1999) (101)
- Evidence for an endogenous peptide ligand for the phencyclidine receptor (1984) (100)
- Neuropeptide receptors in developing and adult rat spinal cord: An in vitro quantitative autoradiography study of calcitonin gene‐related peptide, neurokinins, μ‐opioid, galanin, somatostatin, neurotensin and vasoactive intestinal polypeptide receptors (1995) (100)
- Cell‐type specific activation of p38 and ERK mediates calcitonin gene‐related peptide involvement in tolerance to morphine‐induced analgesia (2009) (99)
- The possible role of the Akt signaling pathway in schizophrenia (2012) (99)
- Reactivity to novelty in cognitively-impaired and cognitively-unimpaired aged rats and young rats (1998) (98)
- Muscarinic receptor subtypes in human neurodegenerative disorders: focus on Alzheimer's disease. (1989) (98)
- Human gliomas and epileptic foci express high levels of a mRNA related to rat testicular sulfated glycoprotein 2, a purported marker of cell death. (1991) (97)
- Characterization of neuropeptide Y, Y2 receptor knockout mice in two animal models of learning and memory processing (2007) (97)
- Increased phosphorylation of cyclic AMP response element-binding protein (CREB) in the superficial dorsal horn neurons following partial sciatic nerve ligation (2001) (97)
- Transthyretin: A key gene involved in the maintenance of memory capacities during aging (2008) (96)
- A microdialysis profile of Met-enkephalin release in the rat nucleus accumbens following alcohol administration. (2005) (96)
- FKHRL1 and its homologs are new targets of nerve growth factor Trk receptor signaling (2002) (95)
- Lewis and Fischer rats: a comparison of dopamine transporter and receptors levels (1998) (95)
- Postnatal handling reduces novelty-induced fear and increases [3H]flunitrazepam binding in rat brain. (1987) (95)
- Insulin-like growth factors-I and -II differentially regulate endogenous acetylcholine release from the rat hippocampal formation. (1997) (94)
- Expression of the purported sigma1 (σ1) receptor in the mammalian brain and its possible relevance in deficits induced by antagonism of the NMDA receptor complex as revealed using an antisense strategy (2000) (93)
- Evidence for the existence of three classes of neurokinin receptors in brain. Differential ontogeny of neurokinin-1, neurokinin-2 and neurokinin-3 binding sites in rat cerebral cortex (1988) (93)
- Insulin-like growth factor-1 (IGF-1) induces the activation/phosphorylation of Akt kinase and cAMP response element-binding protein (CREB) by activating different signaling pathways in PC12 cells (2006) (90)
- Successful Cognitive Aging in Rats: A Role for mGluR5 Glutamate Receptors, Homer 1 Proteins and Downstream Signaling Pathways (2012) (90)
- Synthesis of peptides by the solid-phase method. 6. Neurotensin, fragments, and analogues. (1981) (89)
- Inhibition of neurokinin‐1–substance P receptor and prostanoid activity prevents and reverses the development of morphine tolerance in vivo and the morphine‐induced increase in CGRP expression in cultured dorsal root ganglion neurons (2003) (89)
- International Union of Pharmacology. LXIX. Status of the Calcitonin Gene-Related Peptide Subtype 2 Receptor (2008) (89)
- Autoradiographic distribution of non-dopaminergic binding sites labeled by [3H]haloperidol in rat brain (1987) (88)
- Morphine treatment induced calcitonin gene-related peptide and substance P increases in cultured dorsal root ganglion neurons (2000) (87)
- Inhibition of Src-like Kinases Reveals Akt-dependent and -independent Pathways in Insulin-like Growth Factor I-mediated Oligodendrocyte Progenitor Survival* (2005) (86)
- Muscarinic and nicotinic modulation of cortical acetylcholine release monitored by in vivo microdialysis in freely moving adult rats (1994) (85)
- Localization of sulfated glycoprotein‐2/clusterin mRNA in the rat brain by in situ hybridization (1993) (85)
- Acetylcholine induces neuritic outgrowth in rat primary olfactory bulb cultures (2000) (85)
- High resolution radioautographic localization of [125I]FK-33-824-labelled mu opioid receptors in the spinal cord of normal and deafferented rats (1991) (85)
- Neuronal and inducible nitric oxide synthase expressions and activities in the hippocampi and cortices of young adult, aged cognitively unimpaired, and impaired Long–Evans rats (2002) (84)
- Cholinergic markers in aged cognitively impaired long-evans rats (1995) (84)
- Up‐regulation of interleukin‐6 induced by prostaglandin E2 from invading macrophages following nerve injury: an in vivo and in vitro study (2005) (83)
- Long-Lasting Rescue of Age-Associated Deficits in Cognition and the CNS Cholinergic Phenotype by a Partial Agonist Peptidomimetic Ligand of TrkA (2004) (83)
- Polyphenols as potential inhibitors of amyloid aggregation and toxicity: possible significance to Alzheimer's disease. (2008) (82)
- Evidence That the Inhibition of Luteinizing Hormone Secretion Exerted by Central Administration of Neuropeptide Y (NPY) in the Rat Is Predominantly Mediated by the NPY-Y5 Receptor Subtype1. (1999) (82)
- Peptide E and other proenkephalin-derived peptides are potent kappa opiate receptor agonists (1983) (81)
- Nociceptin receptor antagonists display antidepressant-like properties in the mouse forced swimming test (2002) (79)
- cDNA microarray and proteomic approaches in the study of brain diseases: focus on schizophrenia and Alzheimer's disease. (2003) (79)
- Dopamine D-5 receptor modulates hippocampal acetylcholine release. (2000) (79)
- Autoradiographic localization of a calcium channel antagonist, [3H]nitrendipine, binding site in rat brain (1983) (78)
- Autoradiographic distribution of brain neurokinin-1/substance P receptors using a highly selective ligand [3H]-[Sar9,Met(O2)11]-substance P (1990) (78)
- Possible functions of a new genetic marker in central nervous system: The sulfated glycoprotein‐2 (SGP‐2) (1992) (78)
- Does COX2-dependent PGE2 play a role in neuropathic pain? (2008) (78)
- Further evidence for differential affinity states of the serotonin1A receptor in rat hippocampus (1992) (77)
- Multiple tachykinin receptors in guinea pig brain. High densities of substance K (neurokinin a) binding sites in the substantia nigra (1985) (77)
- Tyrosine-based rivastigmine-loaded organogels in the treatment of Alzheimer's disease. (2010) (77)
- Expression of calcitonin gene-related peptide, substance P and protein kinase C in cultured dorsal root ganglion neurons following chronic exposure to mu, delta and kappa opiates (2002) (76)
- Comparative affinities and antagonistic potencies of various human calcitonin gene-related peptide fragments on calcitonin gene-related peptide receptors in brain and periphery. (1991) (76)
- The hypotensive effect of centrally administered neurotensin in rats. (1981) (76)
- Postweaning social isolation enhances morphological changes in the neonatal ventral hippocampal lesion rat model of psychosis (2008) (76)
- Effect of MPTP and l‐Deprenyl on Antioxidant Enzymes and Lipid Peroxidation Levels in Mouse Brain (1995) (76)
- Calcitonin gene-related peptide as a regulator of neuronal CaMKII–CREB, microglial p38–NFκB and astroglial ERK–Stat1/3 cascades mediating the development of tolerance to morphine-induced analgesia (2010) (75)
- Neuroprotective effects of resveratrol and epigallocatechin gallate polyphenols are mediated by the activation of protein kinase C gamma (2013) (74)
- Post-training injection of the acetylcholine M2 receptor antagonist AF-DX 116 improves memory (1990) (74)
- Antidepressant--anxiolytic interaction: decreased density of benzodiazepine receptors in rat brain following chronic administration of antidepressants. (1984) (73)
- Autoradiographic distribution and receptor binding profile of [125I]Bolton Hunter-rat amylin binding sites in the rat brain. (1994) (73)
- Ionotropic glutamate receptor subtypes in the aged memory-impaired and unimpaired Long–Evans rat (1996) (73)
- Agonist‐ and antagonist‐induced sequestration/internalization of neuropeptide Y Y1 receptors in HEK293 cells (2003) (72)
- Proteomic approaches in brain research and neuropharmacology. (2004) (72)
- Cholinergic markers in Alzheimer disease and the autoregulation of acetylcholine release. (1993) (70)
- Stimulation of Protein Kinase C Modulates Insulin-like Growth Factor-1-induced Akt Activation in PC12 Cells* (2000) (70)
- Nerve Growth Factor Rapidly Induces Prolonged Acetylcholine Release from Cultured Basal Forebrain Neurons: Differentiation between Neuromodulatory and Neurotrophic Influences (2001) (70)
- Increased calcitonin gene‐related peptide in neuroma and invading macrophages is involved in the up‐regulation of interleukin‐6 and thermal hyperalgesia in a rat model of mononeuropathy (2006) (69)
- Role of serotonin (5-HT) in the antidepressant-like properties of neuropeptide Y (NPY) in the mouse forced swim test (2005) (69)
- Peptide YY derivatives as selective neuropeptide Y/peptide YY Y1 and Y2 agonists devoided of activity for the Y3 receptor sub-type. (1994) (68)
- Potent and selective tools to investigate neuropeptide Y receptors in the central and peripheral nervous systems: BIB03304 (Y1) and CGP71683A (Y5). (2000) (67)
- Characteristics and regulation of angiotensin II receptors in pituitary, circumventricular organs and kidney. (1983) (67)
- Differential Binding Profile and Internalization Process of Neurotensin via Neuronal and Glial Receptors (1997) (66)
- Potent human p140-TrkA agonists derived from an anti-receptor monoclonal antibody (1996) (66)
- Group 1 Metabotropic Glutamate Receptor Function and Its Regulation of Learning and Memory in the Aging Brain (2012) (66)
- Acetylcholine release is elicited in the visual cortex, but not in the prefrontal cortex, by patterned visual stimulation: A dual in vivo microdialysis study with functional correlates in the rat brain (2005) (66)
- Evidence that Somatostatin Enhances Endogenous Acetylcholine Release in the Rat Hippocampus (1990) (63)
- Altered Calcitonin Gene‐related Peptide, Substance P and Enkephalin Immunoreactivities and Receptor Binding Sites in the Dorsal Spinal Cord of the Polyarthritic Rat (1994) (63)
- Phencyclidine binding sites in the nucleus accumbens and phencyclidine-induced hyperactivity are decreased following lesions of the mesolimbic dopamine system. (1985) (62)
- Imipramine treatment differentially affects platelet 3H-imipramine binding and serotonin uptake in depressed patients. (1985) (62)
- Therapeutic potential of CNS-active M2 antagonists: novel structures and pharmacology. (1993) (62)
- Neurotoxic consequences of central long-term administration of interleukin-2 in rats (1997) (62)
- Effects of dorsal rhizotomy on neurokinin receptor sub-types in the rat spinal cord: a quantitative autoradiographic study (1991) (61)
- Possible interactions between dynorphin and dopaminergic systems in rat basal ganglia and substantia nigra (1985) (61)
- Distribution and levels of insulin-like growth factor (IGF-I and IGF-II) and insulin receptor binding sites in the spinal cords of amyotrophic lateral sclerosis (ALS) patients. (1996) (61)
- Protective Action of Resveratrol in Human Skin: Possible Involvement of Specific Receptor Binding Sites (2010) (61)
- α7 Nicotinic receptor activation reduces β‐amyloid‐induced apoptosis by inhibiting caspase‐independent death through phosphatidylinositol 3‐kinase signaling (2011) (61)
- Agonist and antagonist activities on human NPFF2 receptors of the NPY ligands GR231118 and BIBP3226 (2001) (60)
- Evidence that the inhibition of luteinizing hormone secretion exerted by central administration of neuropeptide Y (NPY) in the rat is predominantly mediated by the NPY-Y5 receptor subtype. (1999) (60)
- Characterization and autoradiographic distribution of hemicholinium‐3 high‐affinity choline uptake sites in mammalian brain (1987) (60)
- Androgen binding sites in human temporal cortex. (1990) (60)
- A role for adrenomedullin as a pain-related peptide in the rat (2006) (60)
- The role of spinal neuropeptides and prostaglandins in opioid physical dependence (2002) (59)
- Pharmacological characterization of neurotensin receptors in the rat isolated portal vein using analogues and fragments of neurotensin. (1980) (59)
- Heterogeneous binding of [3H]4‐DAMP to muscarinic cholinergic sites in the rat brain: Evidence from membrane binding and autoradiographic studies (1991) (59)
- Dynorphins: Similar relative potencies on μ-, δ- and κ-opiate receptors (1981) (59)
- Quantitative autoradiographic distribution of [125i]bolton-hunter neuropeptide y receptor binding sites in rat brain. comparison with [125i]peptide yy receptor sites (1990) (59)
- Apparent affinity and potency of BIBP3226, a non-peptide neuropeptide Y receptor antagonist, on purported neuropeptide Y Y1, Y2 and Y3 receptors. (1995) (59)
- A role for bombesin in sensory processing in the spinal cord (1984) (59)
- Comparative behavioral changes between male and female postpubertal rats following neonatal excitotoxic lesions of the ventral hippocampus (2003) (59)
- Role of the central benzodiazepine receptor system in behavioral habituation to novelty. (1989) (58)
- Hippocampal GABAergic neurons are susceptible to amyloid-β toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model. (2012) (58)
- Quantitative autoradiographic localization of [125I] neuropeptide Y receptor binding sites in rat spinal cord and the effects of neonatal capsaicin, dorsal rhizotomy and peripheral axotomy (1992) (58)
- gamma-Preprotachykinin-(72-92)-peptide amide: an endogenous preprotachykinin I gene-derived peptide that preferentially binds to neurokinin-2 receptors. (1990) (58)
- Entorhinal cortex lesion induces differential responses in [125I]insulin-like growth factor I, [125I]insulin-like growth factor II and [125I]insulin receptor binding sites in the rat hippocampal formation (1993) (58)
- Comparative laminar distribution of various autoradiographic cholinergic markers in adult rat main olfactory bulb (1995) (58)
- Glutamate Acting on N-Methyl-d-aspartate Receptors Attenuates Insulin-like Growth Factor-1 Receptor Tyrosine Phosphorylation and Its Survival Signaling Properties in Rat Hippocampal Neurons* (2009) (57)
- Cholecystokinin Receptors in Mammalian Brain: A Comparative Characterization and Visualization (1985) (57)
- Insulin‐like growth factor‐I and its receptor in the frontal cortex, hippocampus, and cerebellum of normal human and Alzheimer disease brains (2000) (57)
- Biochemical characterization and autoradiographic localization of central substance P receptors using [125I]physalaemin (1985) (56)
- Comparative pharmacological properties and autoradiographic distribution of [3H]ethylketocyclazocine binding sites in rat and guinea pig brain. (1983) (56)
- Characterization and autoradiographic distribution of [3H]AF-DX 384 binding to putative muscarinic M2 receptors in the rat brain. (1992) (56)
- Pharmacological characterization and autoradiographic localization of substance P receptors in guinea pig brain (1986) (55)
- Neurotrophins differentially enhance acetylcholine release, acetylcholine content and choline acetyltransferase activity in basal forebrain neurons (2001) (55)
- Inhibiting tumor necrosis factor-α before amyloidosis prevents synaptic deficits in an Alzheimer's disease model (2016) (55)
- Compound 48/80 inhibits neurotensin-induced hypotension in rats. (1980) (54)
- Local modulation of hippocampal acetylcholine release by dopamine D1 receptors: a combined receptor autoradiography and in vivo dialysis study (1995) (54)
- Injured nerve-derived COX2/PGE2 contributes to the maintenance of neuropathic pain in aged rats (2010) (54)
- NGF level of is not decreased in the serum, brain-spinal fluid, hippocampus, or parietal cortex of individuals with Alzheimer's disease. (1993) (54)
- Expression of Neuropeptide Y Receptors mRNA and Protein in Human Brain Vessels and Cerebromicrovascular Cells in Culture (1999) (53)
- Pharmacological studies of neurotensin, several fragments and analogous in the isolated perfused rat heart. (1980) (53)
- High Resolution Dissection of Reactive Glial Nets in Alzheimer’s Disease (2016) (53)
- Localization of angiotensin II receptors in rat and monkey kidney by in vitro autoradiography. (1987) (53)
- Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease (2015) (52)
- Aged neuropeptide Y transgenic rats are resistant to acute stress but maintain spatial and non-spatial learning (2004) (52)
- Cloning and Characterization of a Novel Mammalian PP2C Isozyme* (1998) (52)
- Selective blockade of neurotensin-induced coronary vessel constriction in perfused rat hearts by a neurotensin analogue. (1980) (52)
- Autoradiographic distribution of phencyclidine receptors in the rat brain using [3H]1-(1-(2-thienyl)cyclohexyl)piperidine ([3H]TCP) (1986) (51)
- Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors (2005) (51)
- Neuroprotective Effects of Natural Products: Interaction with Intracellular Kinases, Amyloid Peptides and a Possible Role for Transthyretin (2007) (51)
- Comparison of [125I]Bolton-Hunter neuropeptide Y binding sites in the forebrain of various mammalian species (1987) (51)
- Neurotensin receptor binding sites in monkey and human brain: Autoradiographic distribution and effects of 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine treatment (1987) (51)
- FoxO-dependent and -independent mechanisms mediate SirT1 effects on IGFBP-1 gene expression. (2005) (51)
- Calcitonin gene-related peptide (hCGRPα) binding sites in the nucleus accumbens. Atypical structural requirements and marked phylogenic differences (1991) (51)
- Insulin‐like growth factor 1 prevents neuronal cell death induced by corticosterone through activation of the PI3k/Akt pathway (2004) (51)
- Natural antioxidants and neurodegenerative diseases. (2004) (50)
- Platelet 3H-imipramine binding distinguishes depression from Alzheimer dementia. (1985) (50)
- Neuropeptide Y and the Calcitonin Gene‐related Peptide Attenuate Learning Impairments Induced by MK‐801 via a Sigma Receptor‐related mechanism (1997) (50)
- Pain, nociception and spinal opioid receptors (1984) (50)
- Tolerance to the antinociceptive properties of morphine in the rat spinal cord: alteration of calcitonin gene-related peptide-like immunostaining and receptor binding sites. (1995) (50)
- Evidence for the involvement of apoptosis-inducing factor-mediated caspase-independent neuronal death in Alzheimer disease. (2010) (49)
- Applications and current challenges of proteomic approaches, focusing on two-dimensional electrophoresis (2007) (49)
- Opioid receptor subtypes associated with ventral tegmental facilitation and periaqueductal gray inhibition of feeding (1987) (48)
- Characterization of neuropeptide Y receptor subtypes in the normal human brain, including the hypothalamus (1997) (48)
- Potential neurotrophic factors in the mammalian central nervous system: functional significance in the developing and aging brain. (1990) (48)
- [Nphe1]‐Nociceptin (1‐13)‐NH2, a nociceptin receptor antagonist, reverses nociceptin‐induced spatial memory impairments in the Morris water maze task in rats (2000) (48)
- Neuropeptide Y receptor binding sites in human brain. Possible alteration in Alzheimer's disease (1990) (48)
- Chronic phencyclidine treatment decreases phencyclidine and dopamine receptors in rat brain (1982) (48)
- Clozapine administration reverses behavioral, neuronal, and nitric oxide disturbances in the neonatal ventral hippocampus rat (2012) (48)
- Reduction in Acetylcholine Release in the Hippocampus of Dopamine D5 Receptor-Deficient Mice (2004) (48)
- Lipopolysaccharide induces calcitonin gene‐related peptide in the RAW264.7 macrophage cell line (2010) (47)
- Chronic estradiol treatment alters central cholinergic function in the female rat: effect on choline acetyltransferase activity, acetylcholine content, and nicotinic autoreceptor function (1990) (47)
- Widely expressed transcripts for chemokine receptor CXCR1 in identified glutamatergic, γ‐aminobutyric acidergic, and cholinergic neurons and astrocytes of the rat brain: A single‐cell reverse transcription‐multiplex polymerase chain reaction study (2003) (47)
- Neuroprotective and neurorescuing effects of isoform‐specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta‐amyloid toxicity (2001) (47)
- Antisense oligodeoxynucleotides against the muscarinic m2, but not m4, receptor supports its role as autoreceptors in the rat hippocampus. (1999) (47)
- Protective and Rescuing Abilities of IGF‐I and Some Putative Free Radical Scavengers against β‐Amyloid‐Inducing Toxicity in Neurons (1999) (47)
- Effect of nicotine and nicotinic receptor agonists on latent inhibition in the rat. (1996) (47)
- Expression of the neuropeptide Y Y1 receptor mRNA in the human brain: an in situ hybridization study (1996) (46)
- Systemic administration of kainic acid induces selective time dependent decrease in [125I]insulin-like growth factor I, [125I]insulin-like growth factor II and [125I]insulin receptor binding sites in adult rat hippocampal formation (1997) (46)
- Amyloid beta-peptide inhibits high-affinity choline uptake and acetylcholine release in rat hippocampal slices. (1998) (46)
- Comparative behavioral changes in postpubertal rats after neonatal excitotoxic lesions of the ventral hippocampus and the prefrontal cortex (2005) (46)
- Distribution of Peripherally Injected Peptide YY ([125I] PYY (3–36)) and Pancreatic Polypeptide ([125I] hPP) in the CNS: Enrichment in the Area Postrema (2007) (46)
- Comparative Neuroprotective Properties of Stilbene and Catechin Analogs: Action Via a Plasma Membrane Receptor Site? (2009) (46)
- Autoradiographic distribution of multiple classes of opioid receptor binding sites in human forebrain (1987) (46)
- Quantitative autoradiographic distribution of calcitonin gene‐related peptide (hCGRPα) binding sites in the rat and monkey spinal cord (1992) (45)
- Role of neuropeptide Y Y1 and Y2 receptors on behavioral despair in a rat model of depression with co-morbid anxiety (2012) (45)
- AN ANALYSIS OF THE NEGATIVE INOTROPIC ACTION OF SOMATOSTATIN (1979) (45)
- Binding profile of a selective calcitonin gene-related peptide (CGRP) receptor antagonist ligand, [125I-Tyr]hCGRP8-37, in rat brain and peripheral tissues. (1994) (44)
- Autoradiographic localization of substance P receptors using 125I substance P (1982) (44)
- Neuropeptide Y Receptors: Autoradiographic Distribution in the Brain and Structure‐Activity Relationships a (1990) (44)
- Neuropeptide y: role in emotion and alcohol dependence. (2006) (44)
- Multiple cholinergic markers are unexpectedly not altered in the rat dentate gyrus following entorhinal cortex lesions (1994) (44)
- Receptor autoradiography as mean to explore the possible functional relevance of neuropeptides: focus on new agonists and antagonists to study natriuretic peptides, neuropeptide Y and calcitonin gene-related peptides (2004) (44)
- Hypothalamic-pituitary-adrenal activity during chronic central administration of interleukin-2. (1994) (44)
- Comparative autoradiographic distribution of neuropeptide Y Y-1 receptors visualized with the Y1 receptor agonist [125l][Leu31, Pro34]PYY and the non‐peptide antagonist [3H]BIBP3226 (1996) (44)
- Presynaptic Cholinergic Mechanisms in the Rat Cerebellum: Evidence for Nicotinic, but Not Muscarinic Autoreceptors (1989) (44)
- Loss of Quinone Reductase 2 Function Selectively Facilitates Learning Behaviors (2010) (44)
- Application of in vivo microdialysis to the study of cholinergic systems. (2001) (44)
- Evidence for direct and indirect mechanisms in the potent modulatory action of interleukin‐2 on the release of acetylcholine in rat hippocampal slices (1997) (44)
- STRUCTURE‐ACTIVITY STUDIES WITH NEUROTENSIN: ANALYSIS OF POSITIONS 9, 10 and 11 (1980) (44)
- The spinal basis of opioid tolerance and physical dependence: Involvement of calcitonin gene-related peptide, substance P, and arachidonic acid-derived metabolites (2005) (43)
- Stereospecific displacement of [3H]phencyclidine (PCP) receptor binding by an enantiomeric pair of PCP analogs. (1981) (43)
- Evidence for in vivo interactions between neuropeptide Y-related peptides and sigma receptors in the mouse hippocampal formation (1993) (43)
- Involvement of spinal lipoxygenase metabolites in hyperalgesia and opioid tolerance. (2004) (43)
- Stimulation of Dopamine Release from Cultured Rat Mesencephalic Cells by Naturally Occurring Excitatory Amino Acids: Involvement of Both N‐Methyl‐D‐Aspartate (NMDA) and Non‐NMDA Receptor Subtypes (1990) (43)
- Neuropeptide Y-induced contraction is mediated by neuropeptide Y Y2 and Y4 receptors in the rat colon. (1999) (43)
- Quantitative autoradiographic distribution of [3H]AF‐DX 116 muscarinic‐M2 receptor binding sites in rat brain (1989) (43)
- Effects of neonatal ventral hippocampal lesion in rats on stress‐induced acetylcholine release in the prefrontal cortex (2004) (43)
- Endogenous Neurotensin Regulates Hypothalamic‐Pituitary‐Adrenal Axis Activity and Peptidergic Neurons in the Rat Hypothalamic Paraventricular Nucleus (1997) (42)
- Atrial natriuretic factors and the brain: an update (1988) (42)
- Alteration of expression levels of neuronal nitric oxide synthase and haem oxygenase-2 messenger RNA in the hippocampi and cortices of young adult and aged cognitively unimpaired and impaired Long–Evans rats (2000) (42)
- Possible interactions between neurotensin and prostaglandins in the isolated rat portal vein. (1980) (42)
- Neonatal ventral hippocampus lesion leads to reductions in nerve growth factor inducible-B mRNA in the prefrontal cortex and increased amphetamine response in the nucleus accumbens and dorsal striatum (2003) (42)
- Stimulation of CRH‐Mediated ACTH Secretion by Central Administration of Neurotensin: Evidence for the Participation of the Paraventricular Nucleus (1995) (42)
- High levels of specific neuropeptide Y/pancreatic polypeptide receptors in the rat hypothalamus and brainstem. (1996) (41)
- DNA microarrays in neuropsychopharmacology. (2001) (41)
- Deficits in the somatostatin SS1 receptor sub-type in frontal and temporal cortices in Alzheimer's disease (1992) (41)
- Comparative developmental profile of the neuropeptide Y Y1 receptor gene and protein in the rat brain. (1997) (41)
- Alterations in dopaminergic modulation of prefrontal cortical acetylcholine release in post‐pubertal rats with neonatal ventral hippocampal lesions (2004) (41)
- Interleukin‐2 increases choline acetyltransferase activity in septal‐cell cultures (1997) (41)
- Evaluation of truncated neuropeptide Y analogues with modifications of the tyrosine residue in position 1 on Y1, Y2 and Y3 receptor sub-types. (1993) (41)
- Structure-activity study of hCGRP8-37, a calcitonin gene-related peptide receptor antagonist. (1992) (40)
- Neurotensin binding sites in the forebrain and midbrain of the pigeon (1986) (40)
- Hypotensive effects of centrally and peripherally administered neurotensin and neurotensin derivatives in rats (1981) (40)
- Impaired structural hippocampal plasticity is associated with emotional and memory deficits in the olfactory bulbectomized rat (2013) (40)
- [125I]‐GR231118: a high affinity radioligand to investigate neuropeptide Y Y1 and Y4 receptors (2000) (40)
- International perspectives on engaging the public in neuroethics (2005) (39)
- Possible involvement of programmed cell death pathways in the neuroprotective action of polyphenols. (2011) (39)
- A potent and selective CGRP2 agonist, ys(Et)2,7]hCGRPα: comparison in prototypical CGRP1 and CGRP2 in vitro ioassays (1997) (39)
- Glucocorticoid binding sites in human temporal cortex (1988) (39)
- Distribution of Neurotensin Receptors in Mammalian Brain (1992) (39)
- Forkhead box O transcription factors as possible mediators in the development of major depression (2015) (39)
- Expression of cortical and hippocampal apoptosis-inducing factor (AIF) in aging and Alzheimer's disease (2007) (39)
- The involvement of spinal bovine adrenal medulla 22‐like peptide, the proenkephalin derivative, in modulation of nociceptive processing (2007) (38)
- Structural study of the N-terminal segment of neuropeptide tyrosine. (1990) (37)
- Heme oxygenase 1: Another possible target to explain the neuroprotective action of resveratrol, a multifaceted nutrient-based molecule (2010) (37)
- Neonatal exposure to morphine increases mu opiate binding in the adult forebrain. (1983) (37)
- Cellular distribution of insulin-like growth factor-II/mannose-6-phosphate receptor in normal human brain and its alteration in Alzheimer's disease pathology (2006) (37)
- Adrenomedullin receptor binding sites in rat brain and peripheral tissues. (2003) (37)
- Chronotropic and inotropic effects of neurotensin on spontaneously beating auricles. (1978) (36)
- Estradiol valerate and alcohol intake: a comparison between Wistar and Lewis rats and the putative role of endorphins (2003) (36)
- Secretin receptors in the rat kidney: Adenylate cyclase activation and renal effects (1986) (36)
- The distribution of somatostatin binding sites in the brain of gymnotiform fish, Apteronotus leptorhynchus (1994) (36)
- Behavioral and neurochemical alterations following repeated phencyclidine administration in rats with neonatal ventral hippocampal lesions (2000) (36)
- Human brain receptor autoradiography using whole hemisphere sections: A general method that minimizes tissue artefacts (1987) (36)
- Hippocampal gene expression profiling reveals the possible involvement of Homer1 and GABAB receptors in scopolamine‐induced amnesia (2007) (36)
- Long-term effects of BIBN-99, a selective muscarinic M2 receptor antagonist, on improving spatial memory performance in aged cognitively impaired rats (2003) (36)
- Subtypes of excitatory amino acid receptors involved in the stimulation of [3H]dopamine release from cell cultures of rat ventral mesencephalon (1990) (35)
- Phenotypic Alterations in Hippocampal NPY- and PV-Expressing Interneurons in a Presymptomatic Transgenic Mouse Model of Alzheimer’s Disease (2017) (35)
- Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation (2006) (35)
- Rediscovering good old friend IGF-I in the new millenium: possible usefulness in Alzheimer's disease and stroke. (2000) (35)
- Tritium-sensitive film autoradiography of [3H]cholecystokinin-5/pentagastrin receptors in rat brain. (1983) (35)
- Comparative structural requirements of brain neuropeptide Y binding sites and vas deferens neuropeptide Y receptors. (1990) (35)
- Discrete distribution of the neuropeptide Y Y5 receptor gene in the human brain: an in situ hybridization study. (1998) (35)
- Galanin Receptor Binding Sites in Adult Rat Spinal Cord Respond Differentially to Neonatal Capsaicin, Dorsal Rhizotomy and Peripheral Axotomy (1994) (34)
- The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway (2017) (34)
- Comparative localization of putative pre- and postsynaptic markers of muscarinic cholinergic nerve terminals in rat brain. (1985) (34)
- Characterization of binding sites for two classes of calcium channel antagonists in human forebrain. (1985) (34)
- EGb 761 is a neuroprotective agent against beta-amyloid toxicity. (2002) (34)
- Amyloid β peptides and central cholinergic neurons: functional interrelationship and relevance to Alzheimer's disease pathology (2004) (33)
- Certain calcium antagonists are potent displacers of [3H]phencyclidine (PCP) binding in rat brain. (1982) (33)
- Association of neuropeptide Y Y1 receptors with glutamate‐positive and NPY‐positive neurons in rat hippocampal cultures (2000) (33)
- Comparative potencies of substance P, substance K and neuromedin K on brain substance P receptors (1984) (33)
- Blockade of neurotensin binding in the rat hypothalamus and of the central action of neurotensin on the hypothalamic-pituitary-adrenal axis with non-peptide receptor antagonists. (1994) (33)
- Visualization of growth factor receptor sites in rat forebrain (1988) (33)
- Ontogenic profile of the expression of the mu opioid receptor gene in the rat telencephalon and diencephalon: an in situ hybridization study (2000) (33)
- Neurotensin Regulation of Endogenous Acetylcholine Release from Rat Cerebral Cortex: Effect of Quinolinic Acid Lesions of the Basal Forebrain (1990) (33)
- Levomepromazine receptor binding profile in human brain—implications for treatment—resistant schizophrenia (1993) (33)
- Emotional behavior in aged neuropeptide Y (NPY) Y2 knockout mice (2007) (33)
- Spinal administration of lipoxygenase inhibitors suppresses behavioural and neurochemical manifestations of naloxone‐precipitated opioid withdrawal (2003) (32)
- Kappa opioid receptors in human lumbo-sacral spinal cord (1986) (32)
- Spinal modulation of calcitonin gene-related peptide by endocannabinoids in the development of opioid physical dependence (2006) (32)
- Early environment contributes to developmental disruption of MPFC after neonatal ventral hippocampal lesions in rats (2003) (32)
- 125I-FK 33-824: A selective probe for radioautographic labeling of μ opioid receptors in the brain (1986) (32)
- Preferential expression of the neuropeptide Y Y1 over the Y2 receptor subtype in cultured hippocampal neurones and cloning of the rat Y2 receptor (1998) (32)
- An organelle proteomic method to study neurotransmission‐related proteins, applied to a neurodevelopmental model of schizophrenia (2007) (32)
- Platelet 3H-imipramine binding: A state-dependent marker in depression (1984) (31)
- Autoradiographic distribution of putative muscarinic receptor sub-types in mammalian brain. (1993) (31)
- Phencyclidine ("angel dust") analogs and sigma opiate benzomorphans cause cerebral arterial spasm. (1983) (31)
- Cloning and in situ hybridization analysis of the expression of polysialyltransferase mRNA in the developing and adult rat brain. (1997) (31)
- On the possible role of ERK, p38 and CaMKII in the regulation of CGRP expression in morphine-tolerant rats (2011) (30)
- Developmental profiles of various cholinergic markers in the rat main olfactory bulb using quantitative autoradiography (1996) (30)
- Sleep-Wake Cycle Dysfunction in the TgCRND8 Mouse Model of Alzheimer’s Disease: From Early to Advanced Pathological Stages (2015) (30)
- Identification of benzomorphan‐κ opiate receptors in cerebral arteries which subserve relaxation (1984) (30)
- Neurotensin-induced coronary vessels constriction in perfused rat hearts. (1979) (30)
- Quantitative autoradiographic localisation of [125I]endothelin-1 binding sites in spinal cord and dorsal root ganglia of the rat (1991) (29)
- Knockdown of Prodynorphin Gene Prevents Cognitive Decline, Reduces Anxiety, and Rescues Loss of Group 1 Metabotropic Glutamate Receptor Function in Aging (2013) (29)
- Characteristics of 3H-substance P binding sites in rat brain membranes (1984) (29)
- Quantitative radioautographic study of somatostatin receptors heterogeneity in the rat extrahypothalamic brain (1990) (29)
- Glutamate presynaptic vesicular transporter and postsynaptic receptor levels correlate with spatial memory status in aging rat models (2015) (29)
- Characterization of intracellular translocation of Forkhead transcription factor O (FoxO) members induced by NGF in PC12 cells (2011) (29)
- βCTF-correlated burst of hippocampal TNFα occurs at a very early, pre-plaque stage in the TgCRND8 mouse model of Alzheimer's disease. (2013) (28)
- Rabies susceptibility and acetylcholine receptor (1990) (28)
- Upregulation of adrenomedullin in the spinal cord and dorsal root ganglia in the early phase of CFA-induced inflammation in rats (2009) (28)
- Selective reduction in ventral hippocampal acetylcholine release in awake galanin-treated rats and galanin-overexpressing transgenic mice (2004) (28)
- MECHANISMS OF THE CARDIOVASCULAR EFFECTS OF NEUROTENSIN * (1982) (28)
- Increased production of inositol phosphates and diacylglycerol in aged cognitively impaired rats after stimulation of muscarinic, metabotropic-glutamate and endothelin receptors. (1995) (28)
- Systemic administration of kainic acid in adult rat stimulates expression of the chemokine receptor CCR5 in the forebrain (2002) (28)
- Role of Central Calcitonin Gene-Related Peptide (CGRP) in Locomotor and Anxiety- and Depression-Like Behaviors in Two Mouse Strains Exhibiting a CGRP-Dependent Difference in Thermal Pain Sensitivity (2009) (28)
- Distribution of 125I‐neurotensin binding sites in human forebrain: Comparison with the localization of acetylcholinesterase (1990) (27)
- Forkhead family transcription factor FoxO and neural differentiation (2012) (27)
- Autoradiographic distribution of adrenomedullin receptors in the rat brain. (2001) (27)
- A novel muscarinic M(4) receptor antagonist provides further evidence of an autoreceptor role for the muscarinic M(2) receptor sub-type. (1999) (27)
- The role of prostaglandins in hypertension. I. The release of prostaglandins by aorta strips of renal, DOCA-salt, and spontaneously hypertensive rats. (1977) (27)
- Characterization of [3H]AF‐DX 116 binding sites in the rat brain: Evidence for heterogeneity of muscarinic‐M2 receptor sites (1989) (27)
- Developmental and aging aspects of the cholinergicinnervation of the olfactory bulb (1998) (27)
- Neurochemical Deficits in Pathological Brain Aging: Specificity and Possible Relevance for Treatment Strategies (1990) (26)
- A Role for Protein Kinase C-Dependent Upregulation of Adrenomedullin in the Development of Morphine Tolerance in Male Rats (2010) (26)
- Direct visualization of brain M2 muscarinic receptors using the selective antagonist [3H]AF-DX116. (1987) (26)
- Central administration of the neurotensin receptor antagonist, SR48692, modulates diurnal and stress-related hypothalamic-pituitary-adrenal activity. (1997) (26)
- The distribution of tachykinin binding sites in the brain of an electric fish (Apteronotus leptorhynchus) (1994) (26)
- Alteration of calcitonin gene related peptide and its receptor binding sites during the development of tolerance to μ and δ opioids (1995) (26)
- Genomic and proteomic strategies to identify novel targets potentially involved in learning and memory. (2011) (26)
- Effect of Mas‐related gene (Mrg) receptors on hyperalgesia in rats with CFA‐induced inflammation via direct and indirect mechanisms (2013) (26)
- Gene expression profiling following chronic NMDA receptor blockade‐induced learning deficits in rats (2003) (26)
- High density of [3H]Ro 5-4864 'peripheral' benzodiazepine binding sites in the pineal gland. (1984) (25)
- Lithium ions attenuate serum-deprivation-induced apoptosis in PC12 cells through regulation of the Akt/FoxO1 signaling pathways (2016) (25)
- Central Administration of Neurotensin Stimulates Hypothalamic‐Pituitary‐Adrenal Activity (1992) (25)
- The rabbit ileum: a sensitive and selective preparation for the neuropeptide Y Y5 receptor. (1997) (25)
- Strain differences in the behavioural outcome of neonatal ventral hippocampal lesions are determined by the postnatal environment and not genetic factors (2001) (25)
- Possible Role of Dynorphins in Alzheimer's Disease and Age-Related Cognitive Deficits (2013) (25)
- The dog saphenous vein: a sensitive and selective preparation for the Y2 receptor of neuropeptide Y. (1997) (25)
- Morphological evidence for the involvement of microglial p38 activation in CGRP-associated development of morphine antinociceptive tolerance (2010) (24)
- Alterations in Behavioral Responses to a Cholinergic Agonist in Post-Pubertal Rats with Neonatal Ventral Hippocampal Lesions: Relationship to Changes in Muscarinic Receptor Levels (2005) (24)
- Transmitter-replacement Therapy in Alzheimer's Disease Using Intracerebroventricular Infusions of Receptor Agonists (1986) (24)
- Neonatal administration of N-omega-nitro-l-arginine induces permanent decrease in NO levels and hyperresponsiveness to locomotor activity by d-amphetamine in postpubertal rats (2008) (24)
- The effect of L-deprenyl, D-deprenyl and MDL72974 on mitochondrial respiration: a possible mechanism leading to an adaptive increase in superoxide dismutase activity. (1997) (24)
- Presence and differential internalization of two distinct insulin-like growth factor receptors in rat hippocampal neurons (1997) (24)
- Olfactory bulbectomy alters NMDA receptor levels in the rat prefrontal cortex (2000) (24)
- Amiodarone-Induced Retinal Neuronal Cell Apoptosis Attenuated by IGF-1 via Counter Regulation of the PI3k/Akt/FoxO3a Pathway (2017) (24)
- Correlation of regional brain metabolism with receptor localization during ketamine anesthesia: combined autoradiographic 2-[3H]deoxy-D-glucose receptor binding technique. (1982) (24)
- An overview of neuropeptide Y: pharmacology to molecular biology and receptor localization. (2006) (24)
- Cholecystokinin antagonists proglumide, lorglumide and benzotript, but not L-364,718, interact with brain opioid binding sites (1990) (23)
- Neurotoxicity induced by interleukin‐2: Involvement of infiltrating immune cells (1996) (23)
- Signaling pathways relevant to cognition-enhancing drug targets. (2015) (23)
- Targeting invading macrophage- derived PGE2, IL-6 and calcitonin gene-related peptide in injured nerve to treat neuropathic pain (2006) (23)
- Neuropeptide y receptor types in the mammalian brain: Species differences and status in the human central nervous system (1997) (23)
- Developmental profile of neuregulin receptor ErbB4 in postnatal rat cerebral cortex and hippocampus (2007) (23)
- Selective Neurokinin Receptor Radioligands a (1991) (23)
- Autoradiographic evidence for the modulation of in vivo sigma receptor labeling by neuropeptide Y and calcitonin gene-related peptide in the mouse brain. (1996) (23)
- Modulation of NMDA receptors by intrathecal administration of the sensory neuron-specific receptor agonist BAM8–22 (2008) (22)
- Aging and long-term caloric restriction regulate neuropeptide Y receptor subtype densities in the rat brain (2013) (22)
- Insulin-Like Growth Factor-1 – Induced Phosphorylation of Transcription Factor FKHRL 1 Is Mediated by Phosphatidylinositol 3-Kinase / Akt Kinase and Role of This Pathway in Insulin-Like Growth Factor-1 – Induced Survival of Cultured Hippocampal Neurons (2002) (22)
- Radioautographic analysis of somatostatin receptor sub-type in rat hypothalamus (1989) (22)
- Coexistence of central and peripheral benzodiazepine binding sites in the human pineal gland. (1987) (22)
- Localization of kappa opioid receptor binding sites in human forebrain using [3H]U69,593: Comparison with [3H]bremazocine (1987) (21)
- Platelet imipramine binding in patients with panic disorder and major familial depression. (1987) (21)
- BODIPY®‐conjugated neuropeptide Y ligands: new fluorescent tools to tag Y1, Y2, Y4 and Y5 receptor subtypes (2005) (21)
- Characterization and effects on cAMP accumulation of adrenomedullin and calcitonin gene‐related peptide (CGRP) receptors in dissociated rat spinal cord cell culture (2006) (21)
- Characterization of a new neuropeptide Y Y5 agonist radioligand: [125I][cPP(1–7), NPY(19–23), Ala31, Aib32, Gln34]hPP (2004) (21)
- Glucose increases hippocampal extracellular acetylcholine levels upon activation of septal GABA receptors (2003) (21)
- Comparative distribution of neuropeptide Y immunoreactivity and receptor autoradiography in rat forebrain (1988) (21)
- Unchanged platelet 3H-imipramine binding in normal subject after imipramine administration (1985) (21)
- Chronic administration of the Y2 receptor antagonist, JNJ-31020028, induced anti-depressant like-behaviors in olfactory bulbectomized rat (2012) (21)
- An interaction between inositol hexakisphosphate (IP6) and insulin-like growth factor II receptor binding sites in the rat brain. (1994) (21)
- Possible Involvement of Transthyretin in Hippocampal β-Amyloid Burden and Learning Behaviors in a Mouse Model of Alzheimer’s Disease (TgCRND8) (2010) (20)
- Opioid receptor binding profile of [3H]dynorphin A-(1-8) in rat and guinea pig brain. (1984) (20)
- A novel receptor for calcitonin gene‐related peptide (CGRP) mediates secretion in the rat colon: implications for secretory function in colitis (2000) (20)
- Chapter IX Neuropeptide Y, peptide YY and pancreatic polypeptide receptor proteins and mRNAs in mammalian brains (2000) (20)
- Neurotensin Regulation of Endogenous Acetylcholine Release from Rat Striatal Slices Is Independent of Dopaminergic Tone (1991) (20)
- Characterization, distribution and plasticity of atrial natriuretic factor binding sites in brain. (1988) (20)
- Localization of cholecystokinin receptors in relation to the nigrostriatal and mesolimbic dopaminergic pathways (1987) (20)
- Growth Factors and Lymphokines: Modulators of Cholinergic Neuronal Activity (1991) (20)
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- Upregulation of astrocytic α7 nicotinic receptors in Alzheimer's disease brain- possible relevant to amyloid pathology (2012) (0)
- Characterization of 5-HT1D receptor binding sites in post-mortem human brain cortex. (1991) (0)
- Anti-apoptotic action of polyphenols derived from red wine and green tea against beta-amyloid in hippocampal cells (2010) (0)
- Anxiety state and memory abilities in rodent models of successful aging: The free-feeding Lou/C/Jall rat and calorie-restricted Sprague Dawley rat (2012) (0)
- Possible role of various receptor subtypes in modulating the effects of NPY in anxiety and mood disorders (2008) (0)
- Amiodarone-Induced Retinal Neuronal Cell Apoptosis Attenuated by IGF-1 via Counter Regulation of the PI3k/Akt/FoxO3a Pathway (2016) (0)
- 1153 holinergic and peptidergic markers in the Alzheimer's brain: Possible relevance to therapy (1996) (0)
- [3H]phorbol 12,13-dibutyrate/PKC binding in thoracic spinal cord: no change in amyotrophic lateral sclerosis. (1995) (0)
- Reply from Quirion et al. (1988) (0)
- Guest Editorial for the Special Issue Peptide Receptors: Focus on Neuropeptides and Kinins (2010) (0)
- Proteomic changes in the prefrontal cortex of a rat model of schizophrenia (2006) (0)
- Any facts behind the DHEA hype (1997) (0)
- Autoradiographic Distribution of Multiple Opioid, Sigma, and Phencyclidine Receptor Binding Sites in the Human Brain (2020) (0)
- Introduction (2001) (0)
- Forkhead family transcription factor FoxO and neural differentiation (2012) (0)
- The functional analysis of the muscarinic m2 vs. m4 receptors regulating the rat hippocampal acetylcholine release by antisense oligonucleotides (1998) (0)
- Organelle proteomic changes in the prefrontal cortex before the onset of schizophrenia-related symptoms (2007) (0)
- Early expression of cyclin D1 in vulnerable brain areas of TgCRND8 mouse model of Alzheimer's disease (2010) (0)
- Characterization of glutamate receptor subunits in memory-impaired and memory-unimpaired Long Evans aged rats (2010) (0)
- Mitochondrial proteomic changes in the prefrontal cortex of a rat model of schizophrenia (2005) (0)
- Substance P and opioid mechanisms in antinociception produced by noxious cutaneous stimulation in the rat — A physiological and receptor binding study (1992) (0)
- Simvastatin improves cerebrovascular function and reduces soluble amyloid-beta, inflammation and oxidative stress in aged APP mice (2009) (0)
- The Douglas Hospital Research Centre: celebrating 25 years of innovation in mental health research. (2005) (0)
- Nicotine prevents β-amyloid-induced apoptosis by inhibiting mitochondrial death pathway: A role for α7 nicotinic receptor and phosphatidylinositol 3-kinase (PI3K) (2010) (0)
- Brain organoids: are they for real? (2023) (0)
- 24 Apolipoprotein E4 modulates cholinergic activity and cholinergic drug responsiveness in Alzheimer's disease but demonstrates impaired regulation in vivo (1996) (0)
- Contents, Vol. 51, 1990 (1990) (0)
- Differential regulation of human CNS m1–m5 muscarine acetylcholine receptor gene expression in Alzheimer's diseased and age-matched post-mortem control tissues (1993) (0)
- Comparative autoradiographic development of neurokinin receptors in rat brain (1988) (0)
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