Renae Ryan
#123,928
Most Influential Person Now
Australian neuroscientist
Renae Ryan's AcademicInfluence.com Rankings
Renae Ryanbiology Degrees
Biology
#14386
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#18121
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Neuroscience
#2761
World Rank
#2833
Historical Rank
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Biology
Renae Ryan's Degrees
- PhD Neuroscience Monash University
Why Is Renae Ryan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Professor Renae Monique Ryan is the academic director of the Science in Australia Gender Equity Program at the University of Sydney, and a researcher in neuroscience, pharmacology and membrane transport proteins. She argues for systemic change to increase academic diversity.
Renae Ryan's Published Works
Published Works
- Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter (2007) (455)
- Mechanisms of glutamate transport. (2013) (259)
- Targeting glutamine transport to suppress melanoma cell growth (2014) (188)
- The Chloride Permeation Pathway of a Glutamate Transporter and Its Proximity to the Glutamate Translocation Pathway* (2004) (108)
- Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria. (2011) (106)
- Binding and uptake of pulmonary surfactant protein (SP-A) by pulmonary type II epithelial cells. (1989) (105)
- The uncoupled chloride conductance of a bacterial glutamate transporter homolog (2007) (104)
- Functional Characterization of a Na+-dependent Aspartate Transporter from Pyrococcus horikoshii* (2009) (103)
- Distinct Conformational States Mediate the Transport and Anion Channel Properties of the Glutamate Transporter EAAT-1* (2002) (73)
- Position of the Third Na+ Site in the Aspartate Transporter GltPh and the Human Glutamate Transporter, EAAT1 (2012) (69)
- Glycine transport inhibitors for the treatment of pain. (2014) (57)
- Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5 (2018) (51)
- Slips, leaks and channels in glutamate transporters (2008) (44)
- Prostaglandin E2 inhibits calcium current in two sub‐populations of acutely isolated mouse trigeminal sensory neurons (2002) (44)
- Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways (2018) (37)
- A channel in a transporter (2005) (36)
- The position of an arginine residue influences substrate affinity and K+ coupling in the human glutamate transporter, EAAT1 (2010) (34)
- Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma. (2017) (33)
- The domain interface of the human glutamate transporter EAAT1 mediates chloride permeation. (2014) (33)
- Transport Rates of a Glutamate Transporter Homologue Are Influenced by the Lipid Bilayer* (2015) (32)
- Allosteric modulation of neurotransmitter transporters at excitatory synapses. (2004) (31)
- Molecular Determinants for Functional Differences between Alanine-Serine-Cysteine Transporter 1 and Other Glutamate Transporter Family Members* (2013) (31)
- Elevating the alternating-access model (2016) (30)
- Glutamate transporters have a chloride channel with two hydrophobic gates (2021) (30)
- Amino Acid Transporters and Exchangers from the SLC1A Family: Structure, Mechanism and Roles in Physiology and Cancer (2020) (29)
- Monoterpene Glycoside ESK246 from Pittosporum Targets LAT3 Amino Acid Transport and Prostate Cancer Cell Growth (2014) (28)
- Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2. (2017) (25)
- Extracellular Loops 2 and 4 of GLYT2 Are Required for N-Arachidonylglycine Inhibition of Glycine Transport* (2009) (24)
- Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2. (2017) (24)
- Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain. (2019) (22)
- Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2 (2016) (21)
- Na+ Interactions with the Neutral Amino Acid Transporter ASCT1* (2014) (21)
- The Split Personality of Glutamate Transporters: A Chloride Channel and a Transporter (2016) (20)
- Water and urea permeation pathways of the human excitatory amino acid transporter EAAT1. (2011) (19)
- Regulation of Glutamate, GABA and Dopamine Transporter Uptake, Surface Mobility and Expression (2021) (18)
- How and Why Are Channels in Transporters? (2005) (18)
- The Role of Cation Binding in Determining Substrate Selectivity of Glutamate Transporters* (2009) (17)
- Lipid inhibitors of high affinity glycine transporters: Identification of a novel class of analgesics (2014) (17)
- Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics (2019) (16)
- Glycine transporter2 inhibitors: Getting the balance right (2016) (16)
- The amino acid transporter, SLC1A3, is plasma membrane‐localised in adipocytes and its activity is insensitive to insulin (2017) (14)
- Characterization of the Inward- and Outward-Facing Substrate Binding Sites of the Prokaryotic Aspartate Transporter, GltPh. (2016) (13)
- Tuning the ion selectivity of glutamate transporter–associated uncoupled conductances (2016) (10)
- Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia (2021) (9)
- Design, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPK (2014) (8)
- Ataxia-linked SLC1A3 mutations alter EAAT1 chloride channel activity and glial regulation of CNS function (2021) (6)
- Glutamate transporters contain a conserved chloride channel with two hydrophobic gates (2020) (5)
- Correction: Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2 (2016) (5)
- Amino Acid Transporters and Exchangers from the SLC1A Family: Structure, Mechanism and Roles in Physiology and Cancer (2020) (4)
- Site-directed mutagenesis in the study of membrane transporters. (2010) (4)
- Microscopic Characterization of the Chloride Permeation Pathway in the Human Excitatory Amino Acid Transporter 1 (EAAT1) (2021) (3)
- Microscopic Characterization of the Chloride Permeation Pathway in the Human Excitatory Amino Acid Transporter 1 (EAAT1). (2022) (3)
- Site-directed mutagenesis in the study of membrane transporters. (2003) (3)
- Synthesis and in vitro evaluation of diverse heterocyclic diphenolic compounds as inhibitors of DYRK1A. (2018) (3)
- Flexible Analogues of Azaindole DYRK1A Inhibitors Elicit Cytotoxicity in Glioblastoma Cells (2018) (2)
- Acetyl-CoA-Mediated Post-Biosynthetic Modification of Desferrioxamine B Generates N- and N-O-Acetylated Isomers Controlled by a pH Switch. (2022) (2)
- Characterizing unexpected interactions of a glutamine transporter inhibitor with members of the SLC1A transporter family (2022) (2)
- Allosteric Modulation of Glutamate Transporters (2004) (1)
- Author response: Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics (2019) (1)
- Regulation of SLC1A4 and SLC1A5 in Prostate Cancer—Letter (2018) (1)
- Brain transporters: From genes and genetic disorders to function and drug discovery (2016) (1)
- Design , Synthesis , and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p 38 a MAPK (2015) (1)
- Ataxia-linked SLC1A3 mutations alter EAAT1 chloride channel activity and glial regulation of CNS function. (2023) (0)
- The Split Personality of Glutamate Transporters: A Chloride Channel and a Transporter (2015) (0)
- The twisting elevator mechanism of glutamate transporters reveals the structural basis for the dual transport-channel functions. (2022) (0)
- Crystal structure of GltPh in complex with TBOA (2007) (0)
- Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways (2018) (0)
- Molecular Basis for Substrate and Inhibitor Interactions with the Glycine Transporter, GlyT2 (2015) (0)
- 鉛の無い圧電材料(1-x)Na0.5Bi0.5TiO3‐(x)BaTiO3における構造と特性の関係 (2016) (0)
- Crystal Structure of Wild-Type GltPh in complex with L-aspartate (2018) (0)
- A Novel Chloride Conducting Conformation in Human Glutamate Transporters (2021) (0)
- Crystal Structure of GltPh R397C in complex with L-Serine (2018) (0)
- The Split Personality of Glutamate Transporters: a Channel and a Transporter (2018) (0)
- Crystal Structure of GltPh R397C in complex with S-Benzyl-L-Cysteine (2018) (0)
- Faculty Opinions recommendation of Mechanisms of anion conduction by coupled glutamate transporters. (2015) (0)
- Cryo-EM structure of the GltPh L152C-G321C mutant in the intermediate state (2021) (0)
- Crystal structure of GltPh in complex with L-aspartate and sodium ions (2007) (0)
- Cryo-EM structure of the GltPh L152C-G321C mutant in the intermediate chloride conducting state. (2021) (0)
- Crystal Structure of GltPh R397C in complex with L-Cysteine (2018) (0)
- Cryo-EM structure of GltPh L152C-G351C mutant in the intermediate outward-facing state. (2021) (0)
- Directed Mutagenesis in Structure Activity Studies of Neurotransmitter Transporters (2013) (0)
- Crystal structure of GltPh in complex with L-Asp (2007) (0)
- Glutamate transporters have a chloride channel with two hydrophobic gates (2021) (0)
- Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5 (2018) (0)
- Glutamate Transporters (EAATS) Contain a Conserved Chloride Channel with Two Hydrophobic Gates (2021) (0)
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Renae Ryan is affiliated with the following schools: