Renate E. Gay
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(Suggest an Edit or Addition)Renate E. Gay's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny. (1980) (891)
- Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. (2008) (858)
- Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice. (1996) (647)
- Synovial fibroblasts: key players in rheumatoid arthritis. (2006) (588)
- Fibroblast biology: Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis (2000) (498)
- MicroRNA-29, a key regulator of collagen expression in systemic sclerosis. (2010) (492)
- Angiogenic and angiostatic factors in the molecular control of angiogenesis. (2003) (432)
- Interleukin-6 Modulates the Expression of the Bone Morphogenic Protein Receptor Type II Through a Novel STAT3–microRNA Cluster 17/92 Pathway (2009) (388)
- RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via Toll-like receptor 3. (2005) (383)
- Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. (2007) (381)
- Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. (2011) (332)
- Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: toll-like receptor expression in early and longstanding arthritis. (2008) (323)
- Mechanisms of Disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis (2005) (318)
- Collagen content and types in the intestinal strictures of Crohn's disease. (1988) (314)
- Uncontrolled Expression of Vascular Endothelial Growth Factor and Its Receptors Leads to Insufficient Skin Angiogenesis in Patients With Systemic Sclerosis (2004) (314)
- Selective COX-2 Inhibition Improves Endothelial Function in Coronary Artery Disease (2003) (311)
- Anti-tumor necrosis factor-alpha treatment improves endothelial function in patients with rheumatoid arthritis. (2002) (310)
- Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium. (2003) (303)
- DNA hypomethylation in rheumatoid arthritis synovial fibroblasts. (2009) (287)
- Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers (2002) (281)
- Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: two cellular mechanisms explain joint destruction? (1993) (276)
- Pre-B cell colony-enhancing factor/visfatin, a new marker of inflammation in rheumatoid arthritis with proinflammatory and matrix-degrading activities. (2007) (269)
- The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles. (2005) (263)
- Expression of osteoclast differentiation factor in rheumatoid arthritis. (2000) (246)
- Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression. (2000) (215)
- Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients. (2007) (213)
- Chemokine Secretion of Rheumatoid Arthritis Synovial Fibroblasts Stimulated by Toll-Like Receptor 2 Ligands1 (2004) (207)
- Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll-like receptor signaling. (2003) (206)
- Galectin 3 and its binding protein in rheumatoid arthritis. (2003) (190)
- Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction (1999) (184)
- Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of patients with rheumatoid arthritis. (2004) (184)
- Immunohistologic demonstration of platelet-derived growth factor (PDGF) and sis-oncogene expression in scleroderma. (1989) (182)
- Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis. (2007) (178)
- Human IL-1Ra gene transfer into human synovial fibroblasts is chondroprotective. (1997) (178)
- The role of Toll-like receptor signalling in the pathogenesis of arthritis. (2005) (175)
- Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis (2013) (168)
- Detection of interleukin 1beta (IL-1beta), IL-6, and tumor necrosis factor-alpha in skin of patients with fibromyalgia. (2003) (167)
- Overexpression of monocyte chemoattractant protein 1 in systemic sclerosis: role of platelet-derived growth factor and effects on monocyte chemotaxis and collagen synthesis. (2001) (166)
- A new model for rheumatoid arthritis generated by engraftment of rheumatoid synovial tissue and normal human cartilage into SCID mice. (1994) (166)
- Molecular and cellular basis of rheumatoid joint destruction. (2006) (165)
- Expression of sentrin, a novel antiapoptotic molecule, at sites of synovial invasion in rheumatoid arthritis. (2000) (160)
- Differential expression pattern of membrane-type matrix metalloproteinases in rheumatoid arthritis. (2000) (159)
- Increased serum levels of non-collagenous matrix proteins (cartilage oligomeric matrix protein and melanoma inhibitory activity) in marathon runners. (2000) (158)
- Cysteine proteinase cathepsin K mRNA is expressed in synovium of patients with rheumatoid arthritis and is detected at sites of synovial bone destruction. (1998) (154)
- Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis. (2007) (153)
- Epigenetic control in rheumatoid arthritis synovial fibroblasts (2009) (151)
- AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension. (2014) (151)
- SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance (2011) (150)
- Ultrastructural demonstration of apoptosis, Fas and Bcl-2 expression of rheumatoid synovial fibroblasts. (1996) (148)
- Cathepsin B in synovial cells at the site of joint destruction in rheumatoid arthritis. (2010) (148)
- Transitions in collagen types during matrix-induced cartilage, bone, and bone marrow formation. (1977) (146)
- Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance. (2012) (141)
- Expression of the collagenolytic and Ras-induced cysteine proteinase cathepsin L and proliferation-associated oncogenes in synovial cells of MRL/I mice and patients with rheumatoid arthritis. (1990) (140)
- Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts (2007) (138)
- Expression of interleukin-21 receptor in epidermis from patients with systemic sclerosis. (2005) (135)
- The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts (2014) (126)
- DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts (2011) (126)
- Interleukin‐16, produced by synovial fibroblasts, mediates chemoattraction for CD4+ T lymphocytes in rheumatoid arthritis (1998) (120)
- Differential Effects of Selective Cyclooxygenase-2 Inhibitors on Endothelial Function in Salt-Induced Hypertension (2003) (120)
- Synovial tissue protease gene expression and joint erosions in early rheumatoid arthritis. (2001) (120)
- Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3 (2003) (118)
- Simvastatin improves endothelial function in patients with rheumatoid arthritis. (2005) (114)
- Characteristics of bone marrow fibroblast colony-forming cells (CFU-F) and their progeny in patients with myeloproliferative disorders. (1982) (112)
- MicroRNAs in Rheumatoid Arthritis (2012) (112)
- Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions (2017) (111)
- Invasiveness of synovial fibroblasts is regulated by p53 in the SCID mouse in vivo model of cartilage invasion. (2001) (111)
- Dual Role of Autophagy in Stress‐Induced Cell Death in Rheumatoid Arthritis Synovial Fibroblasts (2014) (111)
- Collagenase, cathepsin B and cathepsin L gene expression in the synovial membrane of patients with early inflammatory arthritis. (1999) (110)
- Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCID mouse model. (1999) (110)
- Transcription Factor Fos-Related Antigen-2 Induces Progressive Peripheral Vasculopathy in Mice Closely Resembling Human Systemic Sclerosis (2009) (106)
- Histone deacetylase 7, a potential target for the antifibrotic treatment of systemic sclerosis. (2009) (105)
- Synovial activation in rheumatoid arthritis. (2004) (103)
- Expression of osteopontin messenger RNA and protein in rheumatoid arthritis: effects of osteopontin on the release of collagenase 1 from articular chondrocytes and synovial fibroblasts. (2000) (102)
- Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts. (2012) (102)
- Expression of transient receptor potential vanilloid 1 (TRPV1) in synovial fibroblasts from patients with osteoarthritis and rheumatoid arthritis. (2007) (100)
- Mechanisms of Disease: molecular insights into aseptic loosening of orthopedic implants (2007) (100)
- Collagen formation by the hepatocyte in primary monolayer culture and in vivo. (1983) (99)
- The relationship between plasma microparticles and disease manifestations in patients with systemic sclerosis. (2008) (97)
- Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression. (2010) (95)
- Trichostatin A sensitises rheumatoid arthritis synovial fibroblasts for TRAIL-induced apoptosis (2005) (94)
- Monocyte chemoattractant protein 1 released from glycosaminoglycans mediates its profibrotic effects in systemic sclerosis via the release of interleukin-4 from T cells. (2006) (94)
- Chemokine Secretion of Rheumatoid Arthritis Synovial Fibroblasts Stimulated by Toll-Like Receptor 2 Ligands (2004) (93)
- Expression of vascular cell adhesion molecule-1 mRNA and protein in rheumatoid synovium demonstrated by in situ hybridization and immunohistochemistry. (1995) (93)
- FLICE-inhibitory protein expression in synovial fibroblasts and at sites of cartilage and bone erosion in rheumatoid arthritis. (2002) (91)
- Abundant expression of the interleukin (IL)23 subunit p19, but low levels of bioactive IL23 in the rheumatoid synovium: differential expression and Toll-like receptor-(TLR) dependent regulation of the IL23 subunits, p19 and p40, in rheumatoid arthritis (2008) (91)
- Functional characterization of adherent synovial fluid cells in rheumatoid arthritis: destructive potential in vitro and in vivo. (2003) (89)
- Cooperation of Ras- and c-Myc-dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis. (2004) (89)
- Fra-2 transgenic mice as a novel model of pulmonary hypertension associated with systemic sclerosis (2012) (89)
- Increased DNA fragmentation and ultrastructural changes in fibromyalgic muscle fibres (2004) (88)
- Increased serum levels of antibodies against human cytomegalovirus and prevalence of autoantibodies in systemic sclerosis. (1999) (87)
- Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patients. (1994) (86)
- Expression and function of EZH2 in synovial fibroblasts: epigenetic repression of the Wnt inhibitor SFRP1 in rheumatoid arthritis (2011) (84)
- Comparative analysis of cathepsin L, cathepsin D, and collagenase messenger RNA expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis, by in situ hybridization. (1995) (83)
- Vascular endothelial growth factor aggravates fibrosis and vasculopathy in experimental models of systemic sclerosis (2013) (81)
- MicroRNA-18a Enhances the Interleukin-6-mediated Production of the Acute-phase Proteins Fibrinogen and Haptoglobin in Human Hepatocytes* (2011) (78)
- S100A4 is expressed at site of invasion in rheumatoid arthritis synovium and modulates production of matrix metalloproteinases (2006) (78)
- Galectin-3 is induced in rheumatoid arthritis synovial fibroblasts after adhesion to cartilage oligomeric matrix protein (2004) (77)
- Detection of synovial macrophages in an experimental rabbit model of antigen-induced arthritis: ultrasmall superparamagnetic iron oxide-enhanced MR imaging. (2004) (77)
- Anti-interleukin-1 and anti-CD44 interventions producing significant inhibition of cartilage destruction in an in vitro model of cartilage invasion by rheumatoid arthritis synovial fibroblasts. (2000) (77)
- Ribozymes that inhibit the production of matrix metalloproteinase 1 reduce the invasiveness of rheumatoid arthritis synovial fibroblasts. (2004) (76)
- Chinese hamster lung cells synthesize and confine to the cellular domain a collagen composed solely of B chains. (1980) (75)
- Tumor necrosis factor α-induced microRNA-18a activates rheumatoid arthritis synovial fibroblasts through a feedback loop in NF-κB signaling. (2013) (75)
- Cartilage destruction mediated by synovial fibroblasts does not depend on proliferation in rheumatoid arthritis. (2003) (75)
- Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis (2009) (75)
- Synovial fluid CD146 (MUC18), a marker for synovial membrane angiogenesis in rheumatoid arthritis. (1999) (74)
- Molecular biology of cartilage and bone destruction. (1998) (72)
- Innate immunity, epigenetics and autoimmunity in rheumatoid arthritis. (2009) (72)
- THE MOLECULAR CONTROL OF ANGIOGENESIS (2002) (70)
- Collagen molecules comprised of alpha 1(V)-chains (B-chains): an apparent localization in the exocytoskeleton. (1980) (70)
- Osteoclast-independent bone resorption by fibroblast-like cells (2003) (69)
- Inhibition of fibroblast activation protein and dipeptidylpeptidase 4 increases cartilage invasion by rheumatoid arthritis synovial fibroblasts. (2010) (69)
- Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway (2002) (65)
- Cyclooxygenase- and lipoxygenase-derived eicosanoids in bronchoalveolar lavage fluid from patients with scleroderma lung disease: an imbalance between proinflammatory and antiinflammatory lipid mediators. (2005) (65)
- IL-15 and its role in rheumatoid arthritis (2003) (63)
- Role of nuclear factor κb in synovial inflammation (2002) (63)
- Virus-like particles in synovial fluids from patients with rheumatoid arthritis. (1993) (63)
- Activation of synoviocytes (2000) (62)
- Characterization of the in vitro stromal microenvironment of human bone marrow. (1986) (61)
- Expression, regulation, and signaling of the pattern-recognition receptor nucleotide-binding oligomerization domain 2 in rheumatoid arthritis synovial fibroblasts. (2009) (61)
- Modulation of fibroblast-mediated cartilage degradation by articular chondrocytes in rheumatoid arthritis. (2000) (61)
- Retroviral gene transfer of an antisense construct against membrane type 1 matrix metalloproteinase reduces the invasiveness of rheumatoid arthritis synovial fibroblasts. (2005) (60)
- Collagen types synthesized in dermal fibroblast cultures from patients with early progressive systemic sclerosis. (1980) (58)
- Targeting cathepsin L (CL) by specific ribozymes decreases CL protein synthesis and cartilage destruction in rheumatoid arthritis (2004) (58)
- Changes in the distribution of fibronectin and collagen during development of the neonatal rat heart. (1982) (58)
- Expression of cathepsin K and matrix metalloproteinase 1 indicate persistent osteodestructive activity in long-standing ankylosing spondylitis (2008) (57)
- Nucleofection: a new, highly efficient transfection method for primary human keratinocytes * (2005) (57)
- Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation (2002) (57)
- The role of membrane lipids in the induction of macrophage apoptosis by microparticles (2007) (56)
- The TNF superfamily member LIGHT contributes to survival and activation of synovial fibroblasts in rheumatoid arthritis. (2007) (56)
- The collagens of the joint. (1980) (55)
- Citrullination enhances the pro-inflammatory response to fibrin in rheumatoid arthritis synovial fibroblasts (2012) (55)
- Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts (2004) (55)
- The L1 Retroelement-related p40 Protein Induces p38δ MAP Kinase (2004) (55)
- Demonstration of granzyme A and perforin messenger RNA in the synovium of patients with rheumatoid arthritis. (1995) (55)
- Oncogene activation in rheumatoid synovium (1992) (54)
- Downregulation of miR-193b in systemic sclerosis regulates the proliferative vasculopathy by urokinase-type plasminogen activator expression (2014) (54)
- Inhibition of Spermidine/Spermine N1‐Acetyltransferase Activity: A New Therapeutic Concept in Rheumatoid Arthritis (2014) (53)
- Elevated levels of leukotriene B4 and leukotriene E4 in bronchoalveolar lavage fluid from patients with scleroderma lung disease. (2003) (53)
- Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of a cell surface-targeted plasmin inhibitor. (2000) (51)
- Development and characteristics of a synovial-like interface membrane around cemented tibial hemiarthroplasties in a novel rat model of aseptic prosthesis loosening. (2001) (51)
- Rheumatoid myositis. Clinical and histologic features and possible pathogenesis. (1984) (51)
- The different stages of synovitis: acute vs chronic, early vs late and non-erosive vs erosive. (2005) (51)
- Expression of E-selectin messenger RNA and protein in rheumatoid arthritis. (1995) (50)
- Oncogenes, growth factors, and matrix in the pathogenesis of systemic sclerosis. (1994) (50)
- Association of collagen with preimplantation and peri-implantation mouse embryos. (1980) (50)
- Alteration of the connective tissue network of striated muscle in copper deficient rats. (1985) (50)
- Detection of kappa and delta opioid receptors in skin--outside the nervous system. (2005) (50)
- Synovial fluid exoglycosidases are predictors of rheumatoid arthritis and are effective in cartilage glycosaminoglycan depletion. (2003) (49)
- Persistent high serum levels of cartilage oligomeric matrix protein in a subgroup of patients with traumatic knee injury (1998) (49)
- Alternatively spliced CS-1 fibronectin isoform and its receptor VLA-4 in rheumatoid arthritis synovium. (1997) (48)
- Epigenome Analysis Reveals TBX5 as a Novel Transcription Factor Involved in the Activation of Rheumatoid Arthritis Synovial Fibroblasts (2014) (48)
- Immunohistochemical localization of HTLV-I p19- and p24-related antigens in synovial joints of patients with rheumatoid arthritis. (1989) (46)
- p53 in rheumatoid arthritis synovial fibroblasts at sites of invasion (2003) (46)
- Collagen autoantibodies in patients with vasculitis and systemic lupus erythematosus. (1991) (45)
- Evidence of 5-lipoxygenase overexpression in the skin of patients with systemic sclerosis: a newly identified pathway to skin inflammation in systemic sclerosis. (2001) (41)
- Progressive joint destruction in a human immunodeficiency virus-infected patient with rheumatoid arthritis. (1995) (41)
- Cysteine protease activity is up-regulated in inflamed ankle joints of rats with adjuvant-induced arthritis and decreases with in vivo administration of a vinyl sulfone cysteine protease inhibitor. (2001) (40)
- Discrepancy between mRNA and protein expression of tumour suppressor maspin in synovial tissue may contribute to synovial hyperplasia in rheumatoid arthritis (2004) (40)
- Role of nuclear factor kappaB in synovial inflammation. (2002) (40)
- Analysis of cartilage oligomeric matrix protein (COMP) in synovial fibroblasts and synovial fluids. (1998) (38)
- Regulation and function of SIRT1 in rheumatoid arthritis synovial fibroblasts (2016) (38)
- Prolactin and prolactin-like polypeptides in rheumatoid arthritis. (1999) (38)
- Localization of type V collagen with monoclonal antibodies in developing dental and peridental tissues of the rat and hamster. (1986) (38)
- Activation of the IL-4 STAT Pathway in Rheumatoid Synovium1 (2000) (38)
- Kappa and delta opioid receptors are expressed but down-regulated in fibroblast-like synoviocytes of patients with rheumatoid arthritis and osteoarthritis. (2005) (37)
- Membrane-type-1 matrix metalloproteinase is abundantly expressed in fibroblasts and osteoclasts at the bone-implant interface of aseptically loosened joint arthroplasties in situ. (1999) (37)
- Dual inhibition of 5-lipoxygenase and cyclooxygenases 1 and 2 by ML3000 reduces joint destruction in adjuvant arthritis. (2001) (36)
- Mechanism of joint destruction in rheumatoid arthritis. (1998) (36)
- ATP Induced Brain-Derived Neurotrophic Factor Expression and Release from Osteoarthritis Synovial Fibroblasts Is Mediated by Purinergic Receptor P2X4 (2012) (36)
- Analgesic action of acetaminophen in symptomatic osteoarthritis of the knee. (2006) (35)
- Immunohistochemical and molecular studies of serotonin, substance P, galanin, pituitary adenylyl cyclase-activating polypeptide, and secretoneurin in fibromyalgic muscle tissue. (1998) (34)
- Immunohistochemical Demonstration of Basement Membrane Collagen in Normal Human Skin and in Psoriasis (1979) (33)
- Cellular pathways of joint destruction. (1997) (32)
- Characterisation of the cell type-specificity of collagenase 3 mRNA expression in comparison with membrane type 1 matrix metalloproteinase and gelatinase A in the synovial membrane in rheumatoid arthritis (2002) (32)
- Synovial cell activation (2006) (32)
- Toll-like receptors in rheumatoid arthritis joint destruction mediated by two distinct pathways (2004) (31)
- The SCID mouse model: novel therapeutic targets – lessons from gene transfer (2003) (31)
- Cartilage destruction in granulomatosis with polyangiitis (Wegener's granulomatosis) is mediated by human fibroblasts after transplantation into immunodeficient mice. (2012) (30)
- Expression of proteolytic cathepsins B, D, and L in periodontal gingival fibroblasts and tissues. (1995) (30)
- Smoking induces transcription of the heat shock protein system in the joints (2014) (29)
- Immunohistochemical localization of Type III collagen in the dentin of patients with osteogenesis imperfecta and hereditary opalescent dentin. (1980) (29)
- Protein Tyrosine Phosphatase Nonreceptor Type 2: An Important Regulator of lnterleukin‐6 Production in Rheumatoid Arthritis Synovial Fibroblasts (2015) (28)
- S100A4 (Mts1): is there any relation to the pathogenesis of rheumatoid arthritis? (2006) (28)
- Detection of activated complement complex C5b-9 and complement receptor C5a in skin biopsies of patients with systemic sclerosis (scleroderma). (2000) (27)
- A new double labeling technique for combined in situ hybridization and immunohistochemical analysis. (1994) (27)
- SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts (2014) (27)
- Altered diurnal rhythm of prolactin in systemic sclerosis. (2000) (27)
- Fine structure of cultured human gingival fibroblasts and demonstration of simultaneous synthesis of types I and III collagen. (1980) (27)
- Detection of insulin-like growth factor I and II in synovial tissue specimens of patients with rheumatoid arthritis and osteoarthritis by in situ hybridization. (1995) (26)
- The dual inhibitor of lipoxygenase and cyclooxygenase ML3000 decreases the expression of CXCR3 ligands (2007) (26)
- Immunohistological studies of bone marrow collagen. (1984) (25)
- The pattern-recognition receptor nucleotide-binding oligomerization domain--containing protein 1 promotes production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts. (2012) (25)
- Tie2 as a novel key factor of microangiopathy in systemic sclerosis (2015) (25)
- Characterization of heterotypic adherence between transformed human lymphoblastic cells and marrow stromal cells: VCAM-1 is a ligand for one of the leukemia cell adhesion proteins. (1992) (24)
- Bucillamine induces the synthesis of vascular endothelial growth factor dose-dependently in systemic sclerosis fibroblasts via nuclear factor-kappaB and simian virus 40 promoter factor 1 pathways. (2004) (23)
- Gene therapy in rheumatoid arthritis: how to target joint destruction? (1999) (23)
- Binding of serum immunoglobulins to collagens in IgA nephropathy and HIV infection. (1992) (22)
- “Inverse wrap”: an improved implantation technique for virus-transduced synovial fibroblasts in the SCID mouse model for rheumatoid arthritis (2001) (22)
- The extracellular matrix in "sclerosing" follicular center cell lymphomas: an immunohistochemical and ultrastructural study. (1986) (22)
- Immunohistologic demonstration of type II collagen in synovial fluid phagocytes of osteoarthritis and rheumatoid arthritis patients. (1989) (22)
- The epigenetic architecture at gene promoters determines cell type-specific LPS tolerance. (2017) (21)
- MTX affects inflammation and tissue destruction differently in the rat AA model. (2001) (21)
- Epigenetic deregulation in rheumatoid arthritis. (2011) (21)
- The expression of cyclooxygenase-1, cyclooxygenase-2 and 5-lipoxygenase in inflammatory muscle tissue of patients with polymyositis and dermatomyositis. (2004) (21)
- Growth factors, extracellular matrix, and oncogenes in scleroderma. (1992) (20)
- Morphological studies of the epiphyseal growth zone in the brachymorphic (bm/bm) mouse (1984) (20)
- [Rheumatoid arthritis: new developments in the pathogenesis with special reference to synovial fibroblasts]. (2001) (20)
- Levels of target activation predict antifibrotic responses to tyrosine kinase inhibitors (2013) (20)
- Collagen profile in the transplanted heart. (1990) (20)
- Deficient expression of interleukin-10 receptor alpha chain in rheumatoid arthritis synovium: limitation of animal models of inflammation. (2005) (19)
- Expression of the apoptosis accelerator Bax in rheumatoid arthritis synovium (2003) (19)
- Gene transfer: from concept to therapy (2000) (19)
- DREAM is reduced in synovial fibroblasts of patients with chronic arthritic pain: is it a suitable target for peripheral pain management? (2008) (18)
- Inhibitor of DNA binding/differentiation 2 induced by hypoxia promotes synovial fibroblast-dependent osteoclastogenesis. (2009) (17)
- The L1 retroelement-related p40 protein induces p38delta MAP kinase. (2004) (17)
- Expression and Regulation of PIWIL-Proteins and PIWI-Interacting RNAs in Rheumatoid Arthritis (2016) (16)
- TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles (2018) (16)
- MicroRNAs interfere with DNA methylation in rheumatoid arthritis synovial fibroblasts (2016) (16)
- Expression and function of EZH 2 in synovial fibroblasts : epigenetic repression of the Wnt inhibitor SFRP 1 in rheumatoid arthritis (2011) (15)
- Signaling and effector pathways. (1999) (15)
- Histological and immunohistological identification of collagens in basement membranes of Schwann cells of neurofibromas (1983) (15)
- Prevalence of TTV DNA and GBV-C RNA in patients with systemic sclerosis, rheumatoid arthritis, and osteoarthritis does not differ from that in healthy blood donors (2001) (15)
- Pathological basis of orthopaedic and rheumatic disease (2002) (14)
- Expression of collagenase and potential transcriptional factors c-fos and egr-1 in periodontal gingival fibroblasts. (1992) (14)
- Ex vivo gene transfer in the years to come (2001) (14)
- Changes in the surface of the mouse blastocyst at implantation. (1978) (14)
- Autoantibodies to Basement Membrane Collagen: Epidermolysis Bullosa Simplex versus Bullous Pemphigoid (1980) (14)
- Expression of collagenase and potential transcriptional factors in the MRL/l mouse arthropathy. (1992) (14)
- Gene analysis for exploring the effects of drugs in rheumatoid arthritis. (2005) (14)
- Humoral sensitivity to native collagen types I-VI in the arthritis of MRL/l mice. (1987) (14)
- [Molecular and cellular basis of joint destruction in rheumatoid arthritis]. (2006) (14)
- Functional autoantibodies against serpin E2 in rheumatoid arthritis. (2010) (13)
- Trex-1 deficiency in rheumatoid arthritis synovial fibroblasts. (2010) (13)
- Antisense strategies in degenerative joint diseases: sense or nonsense? (2006) (13)
- Cellular basis and oncogene expression of rheumatoid joint destruction (2004) (13)
- Technology Insight: gene transfer and the design of novel treatments for rheumatoid arthritis (2006) (13)
- Abnormal Accumulation of Basement Membrane (Type IV) and Cytoskeletal (Type V) Collagens in the Strictures of Crohn's Disease (1985) (13)
- Up-regulation of delta-opioid receptors and kappa-opioid receptors in the skin of fibromyalgia patients. (2007) (13)
- Gene transfer as a future therapy for rheumatoid arthritis (2003) (12)
- Gene therapy in osteoarthritis. (2000) (12)
- Retroviral sequences in rheumatoid arthritis synovium. (1998) (12)
- Immunolocalization of types V and XI collagen in cartilage using monoclonal antibodies. (1991) (11)
- Influence of ibuprofen-arginine on serum levels of nitric oxide metabolites in patients with chronic low back pain--a single-blind, placebo controlled pilot trial (ISRCTN18723747). (2006) (11)
- Effects of a novel tyrosine kinase inhibitor in rheumatoid arthritis synovial fibroblasts (2007) (10)
- Small ubiquitin-like modifier 1 [corrected] mediates the resistance of prosthesis-loosening fibroblast-like synoviocytes against Fas-induced apoptosis. (2009) (10)
- Functional genomics of fibroblasts (2004) (10)
- Trichostatin-A sensitizes rheumatoid arthritis synovial fibroblasts for TRAIL-induced apoptosis (2005) (10)
- Cartilage destruction in rheumatoid arthritis (2002) (9)
- Absence of inducible retroviruses from synovial fibroblasts and synovial fluid cells of patients with rheumatoid arthritis. (2002) (9)
- Expression of the precursor of secretoneurin, secretogranin II, in the synovium of patients with rheumatoid arthritis and osteoarthritis. (2000) (8)
- Multiple collagen gene expression with type III predominance in rat mucosal keratinocytes. (1982) (8)
- Detection of mRNA by non-radioactive direct primed in situ reverse transcription (2001) (7)
- Bone Marrow Derived Cells Express Human T‐Cell Lymphotropic Virus Type I (HTLV‐I)‐Related Antigens in Patients with Multiple Sclerosis (1988) (7)
- Expression and localization of opioid receptors in muscle satellite cells: no difference between fibromyalgia patients and healthy subjects. (2003) (7)
- AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts (2016) (7)
- Induction of p16 at sites of cartilage invasion in the SCID mouse coimplantation model of rheumatoid arthritis. (2003) (7)
- [Fusion of vertebrae and the sacroiliac joint by cartilaginous tissue in HLA-B27 transgenic rats]. (1996) (6)
- Rectovaginal constriction (RVC) in Jersey cattle: VI. Immunohistochemical studies of collagen. (1986) (6)
- Intracellular secretory pathway and ultrastructural localization of interstitial procollagenase in human gingival fibroblasts. (1990) (6)
- AspIrin causes in vivo synthesis of type i collagen by atrophic articular cartilage. (1983) (6)
- Increased expression of the gene for the pro alpha 1(IV) chain of basement-membrane procollagen in cultured skin fibroblasts from two variants of osteogenesis imperfecta. (1989) (6)
- Delivery of antisense constructs and ribozymes to inhibit cartilage destruction in the SCID mouse model of RA (2001) (6)
- Dermal fibrosis in spinal cord injury patients: a scleroderma variant? (1980) (6)
- Gene targeting: Roadmap to future therapies (2004) (5)
- HIF-1 mediated upregulation of VEGF and VEGF-R in systemic sclerosis (SSc): Imbalance with angiostatic factors suggests VEGF as a novel option for the treatment of ischemia in patients with SSc (2002) (5)
- Novel strategies for the therapy of rheumatoid arthritis. (1997) (5)
- Chemokines and chemokine receptors in the pathogenesis of systemic sclerosis (2002) (5)
- Synovial mesenchymal reaction as a perpetuating principle. (1995) (4)
- Toll-like receptor expression in synovial fibroblasts and normal skin fibroblasts and induction of matrix metallo-proteinase expression by various Toll-like receptor ligands (2005) (4)
- [Rheumatoid arthritis: new molecular and cellular aspects]. (1999) (3)
- BAFF levels in patients with ankylosing spondylitis and response to anti-tumor necrosis factor treatment. (2013) (3)
- Differential gene expression of proliferating synovial fibroblasts in rheumatoid arthritis (2002) (3)
- Double and triple gene transfer in arthritis (2001) (3)
- UvA-DARE ( Digital Academic Repository ) SIRT 1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance (2017) (3)
- The extracellular matrix in large-cell lymphomas: a histopathologic, immunohistochemical, and ultrastructural study. (1989) (3)
- Activation of Synovial Fibroblasts in Rheumatoid Arthritis (1999) (2)
- FRI0351 The Feedback Loop between Long Noncoding RNA NRON and NFAT5 Regulates the Inflammatory Response of Rheumatoid Arthritis Synovial Fibroblasts (2014) (2)
- [Synovial fibroblasts from patients with rheumatoid arthritis transplanted in SCID mice destroy normal human cartilage and expressed VCAM-1 and cathepsins]. (1996) (2)
- MiRs in RA: possible biomarkers and therapeutic targets (2012) (2)
- AB0071 Dual role of autophagy in stress-induced cell death in rheumatoid arthritis synovial fibroblasts (2013) (2)
- Transfer of protease inhibitors to inhibit cartilage destruction (2001) (1)
- FRI0077 Levels of mir-16 in serum associate with response to therapy in patients with early rheumatoid arthritis (2013) (1)
- Expression of focal adhesion kinase, Akt/PKB, Elk-1 and p90RSK in rheumatoid arthritis tissues but not at sites of cartilage invasion (2003) (1)
- Inhibition of RNA polymerases by digoxigenin-labeled UTP. (1994) (1)
- Molecular basis of rheumatoid joint destruction: analogies to the pathogenesis of autoimmunity in diabetes. (1996) (1)
- A one-day double-labelling technique for tissue specimens: Immunogold-silver staining forin situ hybridization combined with alkaline phosphatase-anti-alkaline phosphatase (APAAP) immunohistochemistry for antigens (1996) (1)
- OP0022 Molecular profile of rheumatoid arthritis-synovial fibroblasts during proliferation (2001) (1)
- A3.19 mIR-193B induces UPA in SSC and contributes to the proliferative vasculopathy via uPAR independent pathways (2013) (1)
- Enzymatic detection systems for non-isotopic in situ hybridization using biotinylated cDNA probes (1995) (1)
- AAA-ATPase p 97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts (2017) (1)
- AB0032 Toll-like receptor stimulation induces tolerizable and non-tolerizable effects in rheumatoid arthritis synovial fibroblasts (2013) (1)
- THU0115 Epigenetic Repression of the Long Noncoding Rna Hotair Regulates NF-KB Signalling and the Expression of Matrix Metalloproteases in Synovial Fibroblasts (2013) (1)
- Effects of TIMP-1 and TIMP-3 gene transfer on invasiveness, proliferation and apoptosis of rheumatoid arthritis (RA) synovial fibroblasts (RA-SF) (2002) (1)
- 227 DIFFERENTIAL “PAIN” GENE EXPRESSION AND MODULATION EXERTED BY ATP IN SYNOVIAL FIBROBLASTS FROM PATIENTS WITH SYMPTOMATIC OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS (2009) (1)
- OP0110 Bet Bromodomain Proteins Regulate the Matrix Degrading and Inflammatory Properties of Rheumatoid Arthritis Synovial Fibroblasts (2014) (1)
- THU0043 AAA-ATPASE P97 Regulates Apoptotic and Autophagy-Associated Cell Death in Arthritis (2015) (1)
- A3.09 Synovial fibroblasts as determinants for arthritis specific pattern of joint involvement (2016) (1)
- In situ hybridization of synovial tissue. (2007) (1)
- Gene transfer in rheumatoid arthritis: a novel therapeutic approach. (2000) (1)
- Bacterial peptidoglycan stimulates integrin expression and MMP production of synovial fibroblasts (2002) (1)
- [Synovial fibroblasts : Main players in rheumatoid arthritis]. (2016) (1)
- SAT0063 Functional analysis of the primary cilium in rheumatoid arthritis synovial fibroblasts (2013) (1)
- Viral, Nonviral and Peptide-Mediated Intra-Articular Transfer of Genes and Proteins (2001) (1)
- OP0106 The Impact of Pro-Inflammatory Cytokines on the Expression and Function of Long Noncoding RNA (LNCRNA) in Rheumatoid Arthritis Synovial Fibroblasts (2014) (1)
- Cigarette smoke downregulates HDAC2 in rheumatoid arthritis synovial fibroblasts (2012) (1)
- Long-term treatment of the MRL/lpr mouse with methotrexate and 10-deazaaminopterin (2005) (1)
- OP0133 DNA Demethylation Pathway Analysis in Rheumatoid Arthritis Synovial Fibroblasts and Macrophages (2016) (0)
- OP0040 Bucillamine and its metabolites induce synthesis of vegf dose dependently in systemic sclerosis fibroblasts via the nf-kb pathway (2001) (0)
- THU0104 In vivo and in vitro investigations of the tumour suppressor p16 in rheumatoid arthritis (2001) (0)
- OP0181 Vegf induces vasculopathy and fibrosis in vivo closely resembling human systemic sclerosis (2013) (0)
- Dermal fibrosis secondary to autonomic dysfunction following spinal cord injury (1984) (0)
- A7.3 Association of Circulating miR-223 and miR-16 with Disease Activity in Patients with Early Rheumatoid Arthritis (2013) (0)
- In Vitro and in Vivo Gene Delivery using a Lentiviral Vector (2001) (0)
- Floating anchorage-independent fibroblast-like cells mediate cartilage destruction independently from the hyperplastic synovial tissue (2003) (0)
- THU0049 Protein kinase inhibition enhances steady state mrna levels encoding il -16 but reduces il-18 encoding message levels in fibroblasts (2001) (0)
- Ultrastructural pathway of human fibroblast collagenase and distribution in tissues of rheumatoid joint destruction. (1992) (0)
- Molecular pain signalling in joints (2003) (0)
- Rheumatoid Synovium Activation of the IL-4 STAT Pathway in (2000) (0)
- [Systemic sclerosis. Objectives for the treatment]. (2009) (0)
- THU0113 Expression of galectin-3 in rheumatoid arthritis synovium (2001) (0)
- CHARACTERIZATION OF THE COLLAGEN TYPES IN NORMAL AND INFLAMMED HUMAN INTESTINE (1984) (0)
- Update on the Contralateral Effect in Rabbit and Mouse Models (2001) (0)
- SAT0230 Microrna-29C Limits the Effects of Methyl Donors on DNA Methylation in Rheumatoid Arthritis Synovial Fibroblasts (2015) (0)
- AB0028 Smoking induces expression of mic ligands of the activating immune receptor nkg2d (2013) (0)
- AB0348 The adverse effect of methotrexate on synovial fibroblasts in vitro (2013) (0)
- Induction of Synovial Apoptosis by Gene Transfer and Peptide Mediated Protein Transduction (2001) (0)
- [Messenger RNA expression of alternatively spliced CS-1 fibronectin isoforms in Rheumatoid arthritis (RA) synovium]. (1996) (0)
- THU0056 Expression of Piwi-interacting RNA in Rheumatoid Arthritis (2015) (0)
- THU0092 The l1 mrna in rheumatoid arthritis encodes a functional retrotransposable element (2001) (0)
- FRI0049 Surface proteins on microparticles can induce resistance of rheumatoid arthritis synovial fibroblasts to apoptosis mediated by death receptors (2013) (0)
- OP0229 MIR-193B Induces uPA in SSC and Contributes to the Proliferative Vasculopathy Via uPAR Independent Pathways (2013) (0)
- AB0027 A Novel Transcription Factor NFAT5 Plays An Important Role as Critical Regulator in The Inflammatory Response of Rheumatoid Arthritis Fibroblasts Mediated via Toll-Like Receptor 4 Signaling Pathways (2016) (0)
- Transfer and Intra-Articular Expression of the IL-1Ra cDNA in Human Rheumatoid Joints (2001) (0)
- A9.13 TNF-Induced- Protein Tyrosine Phosphatase Nonreceptor Type 2 (PTPN2) as a Negative Regulator of Inflammation in Rheumatoid Arthritis (2013) (0)
- AB0837 Circulating micrornas in systemic sclerosis patients reflect microrna profile of cultured scleroderma fibroblasts and correlate with distinct disease features (2013) (0)
- FRI0359 Methyl Donors Change the Expression Profile of Mir-203 and Mir-29C in Rheumatoid Arthritis Synovial Fibroblasts (2014) (0)
- THU0071 Protein Tyrosine Phosphatase Nonreceptor Type 2 (PTPN2) is an Important Regulator of Inflammation and Autophagy in Rheumatoid Arthritis (2013) (0)
- AB0186 BAFF levels in patients with ankylosing spondylitis and response to anti-tumor necrosis factor treatment (2013) (0)
- "Inverse wrap": an improved implantation technique for virus-transduced synovial fibroblasts in the SCID mouse model for rheumatoid arthritis (2001) (0)
- OP0256 SIRT1 Regulates Cigarette Smoke-Induced IL8 Expression and TNFA-Mediated Il6 Release in Rheumatoid Arthritis Synovial Fibroblasts (2013) (0)
- Galectin-3 and galectin-3 binding protein in rheumatoid arthritis (2003) (0)
- SAT0024 Epigenetic Analysis of Lps-Induced Tolerance in Rheumatoid Arthritis Synovial Fibroblasts and Macrophages (2016) (0)
- OP0018 Microrna-145 down-regulation in systemic sclerosis is limited to skin fibroblasts and influenced by epigenetic modifications and negative feedback loop by TGF-β (2013) (0)
- THU0109 The destructive process of rheumatoid arthritis synovial fibroblasts (ra-sf) is independent of p53 (2001) (0)
- University of Birmingham Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis (2013) (0)
- OP0259 The Bromodomain Protein BRD1 Regulates the Matrix Degrading and Inflammatory Properties of Rheumatoid Arthritis Synovial Fibroblasts (2015) (0)
- SAT0064 The expression of HDAC6 is reduced in rheumatoid arthritis synovial fibroblasts (2013) (0)
- Toll-Like Receptor 2 Ligands Arthritis Synovial Fibroblasts Stimulated by Chemokine Secretion of Rheumatoid (2003) (0)
- SAT0056 Dna methylation analysis identified TBX5 as an important transcription factor in rheumatoid arthritis (2013) (0)
- Pathobiochemistry of connective tissue in breast cancer. (1985) (0)
- High-resolution molecular analysis for research in rheumatology (2006) (0)
- Expression , regulation and signaling of the pattern-recognition receptor NOD 2 in rheumatoid arthritis synovial fibroblasts (2009) (0)
- OP0154 Altered lymph node stromal cells during the earliest phases of rheumatoid arthritis (2017) (0)
- Immune cell - derived microparticles contribute to the resistance of rheumatoid arthritis synovial fibroblasts to death receptor-mediated apoptosis (2012) (0)
- Year : 2002 Ex vivo gene transfer in the years to come Pap (2007) (0)
- Activation of synovial fibroblasts via Toll-like receptor signaling (2003) (0)
- OP0257 Characterization of a DNA Demethylation Pathway During Inflammation in Macrophages (2015) (0)
- OP0326 Epigenetically-driven distal expression of the lncrna hottip shapes inflammatory, adhesive and proliferative characteristics of hand synovial fibroblasts in arthritis (2017) (0)
- Mechanisms of resistance against Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts (2003) (0)
- SAT0126 Expression of opioid receptors in chronic pain patients with fibromyalgia, osteoarthritis, psychosis, rheumatoid arthritis and healthy controls (2001) (0)
- THU0043 The expression of cyclooxygenase, lipooxygenase and neuropeptides in muscle tissue of patients with polymyositis and dermatomyositis (2001) (0)
- Regulation and function of SIRT1 in rheumatoid arthritis synovial fibroblasts (2015) (0)
- P 3 Clinical evaluation of autologous chondrocytes for joint repair (2001) (0)
- OP0256 Changes of Microrna Expression in Lymph Node Stromal Cells of Rheumatoid Arthritis Patients (2014) (0)
- Gene transfer of protective cytokines in rheumatoid arthritis. (2001) (0)
- SAT0565 The Expression and Regulation of the Argonaute Protein Family Member PIWIL4 in RA (2014) (0)
- THU0097 The discrepancy between mrna and protein expression of the tumour-suppressor gene maspin in synovial tissue might contribute to synovial hyperplasia in rheumatoid arthritis (ra) (2001) (0)
- 228 EXPRESSION OF BRAIN DERIVED NEUROTROPHIC FACTOR IN SYNOVIAL FIBROBLASTS FROM PATIENTS WITH OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS (2009) (0)
- FRI0350 The Scaffold Protein P62 Regulates Cell Death, Autophagy and the Ubiquitin-Proteasome System in Rheumatoid Arthritis Synovial Fibroblasts (2014) (0)
- AB0114 Comparative Analysis of the Expression of Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2) in Autoimmune Disease (2014) (0)
- Do antivirals have any utility in the treatment of arthritis? (1998) (0)
- SP0099 Synovial fibroblasts degrading cartilage and bone (2001) (0)
- Microparticles from inflammatory cells are strong inducers of matrix metalloproteinases and inflammatory cytokines in synovial fibroblasts (2005) (0)
- THU0041 Microparticle-Associated Poly(I:C) is Resistant to Rnase III Degradation and Protects Rheumatoid Arthritis Synovial Fibroblasts from Trail-Induced Apoptosis (2013) (0)
- OP0007 Deep Rna Sequencing Reveals Arthritis-Specific Lncrna Transcriptomes of Synovial Fibroblasts at Different Anatomic Locations (2016) (0)
- Insufficient Skin Angiogenesis in Patients With Systemic Sclerosis Uncontrolled Expression of Vascular Endothelial Growth Factor and Its Receptors Leads (2004) (0)
- Expression of galectin-3 in rheumatoid arthritis synovium (2002) (0)
- SAT0105 Circulating MIR-223 is downregulated in SERA of patients with early RA after treatment with methotrexate (2013) (0)
- The inhibitor of differentiation-2 promotes synovial fibroblast-dependent osteoclastogenesis in rheumatoid arthritis (2005) (0)
- O008 Altered lymph node stromal cells during the earliest phases of rheumatoid arthritis (2017) (0)
- THU0076 Differential Dna Methylation of TBX5 Transcription Factor in Synovial Fibroblasts from Resolving Arthritis and Rheumatoid Arthritis at Different Stages of Evolution (2013) (0)
- AB0206 Investigation of the inducibility of retroviruses from rheumatoid arthritis synovial fibroblasts (ra-sf) and ra-synovial fluid cells (ra-sfc) (2001) (0)
- SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts (2014) (0)
- OP0071 Positional Coding and Noncoding Transcriptomes of Synovial Fibroblasts in Joint Specific Patterns of Arthritis (2015) (0)
- OP0017 The tnf-alpha-induced MIR-18A activates rheumatoid arthritis synovial fibroblast through a positive feedback loop in NF-KAPPA B signalling (2013) (0)
- Smoking induces expression of ligands of the immune receptor NKG2D (2012) (0)
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