Richard A. Solano Beach Houghten
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Chemistry
Richard A. Solano Beach Houghten's Degrees
- PhD Chemistry University of California, San Diego
- Bachelors Chemistry University of California, San Diego
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(Suggest an Edit or Addition)Richard A. Solano Beach Houghten's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. (1985) (1415)
- Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery (1991) (1024)
- Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence (1982) (795)
- The structure of an antigenic determinant in a protein (1984) (794)
- Folding of immunogenic peptide fragments of proteins in water solution. I. Sequence requirements for the formation of a reverse turn. (1988) (599)
- Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity. (2004) (442)
- Folding of immunogenic peptide fragments of proteins in water solution. II. The nascent helix. (1988) (435)
- The Current Status of Heterocyclic Combinatorial Libraries. (1997) (430)
- The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein (1984) (427)
- An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes. (1988) (394)
- Shifting from the single to the multitarget paradigm in drug discovery. (2013) (373)
- Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition. (1983) (360)
- A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform. (1997) (343)
- Topology of the 32‐kd liver gap junction protein determined by site‐directed antibody localizations. (1988) (335)
- Design of model amphipathic peptides having potent antimicrobial activities. (1992) (321)
- The value of antimicrobial peptides in the age of resistance. (2020) (312)
- Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries. (1992) (308)
- Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immunodominant T-cell domains map to the polymorphic regions of the molecule. (1988) (263)
- Hemolytic and antimicrobial activities of the twenty-four individual omission analogues of melittin. (1991) (255)
- Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease (1999) (235)
- Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes (1990) (208)
- Mapping the Prion Protein Using Recombinant Antibodies (1998) (205)
- Structure of the von Willebrand factor domain interacting with glycoprotein Ib. (1988) (205)
- The immunodominant site of a synthetic immunogen has a conformational preference in water for a type-II reverse turn (1985) (201)
- Polyarginines Are Potent Furin Inhibitors* (2000) (197)
- Mixture-based synthetic combinatorial libraries. (1999) (186)
- Synthetic factor VIII peptides with amino acid sequences contained within the C2 domain of factor VIII inhibit factor VIII binding to phosphatidylserine. (1990) (185)
- Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology. (1998) (184)
- Identification of an epitope in the major envelope protein of Epstein-Barr virus that mediates viral binding to the B lymphocyte EBV receptor (CR2) (1989) (182)
- Identification of a site in the alpha chain of platelet glycoprotein Ib that participates in von Willebrand factor binding. (1990) (174)
- Chemical basis of antigenic variation in foot-and-mouth disease virus (1983) (171)
- Cytotoxic T cells specific for the circumsporozoite protein of Plasmodium falciparum (1988) (165)
- Interleukin 2 production in vitro by peripheral lymphocytes in response to human papillomavirus-derived peptides: correlation with cervical pathology. (1996) (161)
- A single amino acid interchange yields reciprocal CTL specificities for HIV-1 gp160. (1989) (156)
- An epitope in hepatitis C virus core region recognized by cytotoxic T cells in mice and humans (1994) (155)
- Polyalanine-based peptides as models for self-associated beta-pleated-sheet complexes. (1997) (154)
- Human cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein. (1991) (151)
- Probing degeneracy in T-cell recognition using peptide combinatorial libraries. (1998) (151)
- Characterization of Activity Landscapes Using 2D and 3D Similarity Methods: Consensus Activity Cliffs (2009) (149)
- Induction of broadly cross-reactive cytotoxic T cells recognizing an HIV-1 envelope determinant. (1992) (145)
- Peptide libraries: Determination of relative reaction rates of protected amino acids in competitive couplings (1994) (144)
- Influence of protein flexibility and peptide conformation on reactivity of monoclonal anti-peptide antibodies with a protein alpha-helix. (1987) (143)
- "Libraries from libraries": chemical transformation of combinatorial libraries to extend the range and repertoire of chemical diversity. (1994) (142)
- Induction of neonatal tolerance by plasmid DNA vaccination of mice. (1996) (140)
- Chemoinformatic Analysis of Combinatorial Libraries, Drugs, Natural Products, and Molecular Libraries Small Molecule Repository (2009) (136)
- Specificity and degeneracy of T cells. (2004) (132)
- Simplified procedure for carrying out simultaneous multiple hydrogen fluoride cleavages of protected peptide resins. (2009) (130)
- Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells. (2005) (129)
- Visualization of the Chemical Space in Drug Discovery (2008) (125)
- Expanding the medicinally relevant chemical space with compound libraries. (2012) (123)
- Peptides: The Wave of the Future (2001) (121)
- The importance of dominant negative effects of amino acid side chain substitution in peptide-MHC molecule interactions and T cell recognition. (1993) (119)
- An immunogenic region within residues Val1670-Glu1684 of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor. (1988) (117)
- Reduction of sulfoxides in peptides and proteins. (1979) (116)
- Degeneracy of Antigen Recognition as the Molecular Basis for the High Frequency of Naive A2/Melan-A Peptide Multimer+ CD8+ T Cells in Humans (2002) (114)
- Exploring immunological specificity using synthetic peptide combinatorial libraries. (1999) (114)
- Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods. (2008) (113)
- Inhibition of Furin by Polyarginine-containing Peptides (2004) (112)
- A T cell clone directed at the circumsporozoite protein which protects mice against both Plasmodium yoelii and Plasmodium berghei. (1992) (111)
- Integrating virtual screening and combinatorial chemistry for accelerated drug discovery. (2011) (107)
- Inhibition of platelet function with synthetic peptides designed to be high-affinity antagonists of fibrinogen binding to platelets. (1986) (104)
- Immune response to uncoupled peptides of foot-and-mouth disease virus. (1987) (104)
- Site-directed serology with synthetic peptides representing the large glycoprotein G of respiratory syncytial virus. (1987) (104)
- Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein (1989) (99)
- beta-Endorphin: stability, clearance behavior, and entry into the central nervous system after intravenous injection of the tritiated peptide in rats and rabbits. (1980) (99)
- Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors. (2008) (95)
- Cellular, Biochemical, and Genetic Analysis of Mechanism of Small Molecule IAP Inhibitors* (2004) (94)
- Novel antimicrobial compounds identified using synthetic combinatorial library technology. (1996) (93)
- Induced conformational states of amphipathic peptides in aqueous/lipid environments. (1995) (93)
- Advances in the use of synthetic combinatorial chemistry: Mixture-based libraries (2003) (92)
- Immunological priming with synthetic peptides of foot-and-mouth disease virus. (1985) (92)
- Solid-phase synthesis of trisubstituted bicyclic guanidines via cyclization of reduced N-acylated dipeptides (1998) (90)
- Investigation of antigen-antibody interactions using a soluble, non-support-bound synthetic decapeptide library composed of four trillion (4 x 10(12) sequences. (1994) (89)
- Identification of substrate-analog trypsin inhibitors through the screening of synthetic peptide combinatorial libraries. (1993) (88)
- Conserved T and B cell epitopes on the M protein of group A streptococci. Induction of bactericidal antibodies. (1992) (87)
- Identification of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a combinatorial chemical library. (1995) (86)
- The Use of Synthetic Peptides in the Formation of Biophysically and Biologically Active Pulmonary Surfactants (1991) (85)
- Mu-Opioid receptor biased ligands: A safer and painless discovery of analgesics? (2017) (84)
- Irradiated sporozoite vaccine induces HLA-B8-restricted cytotoxic T lymphocyte responses against two overlapping epitopes of the Plasmodium falciparum sporozoite surface protein 2 (1995) (84)
- Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIII heavy chain. (1988) (83)
- The Role of Amphipathicity in the Folding, Self-association and Biological Activity of Multiple Subunit Small Proteins (*) (1995) (83)
- Immunoreactivity of a 10-kDa antigen of Mycobacterium tuberculosis. (1992) (83)
- An epitope in human immunodeficiency virus 1 reverse transcriptase recognized by both mouse and human cytotoxic T lymphocytes. (1990) (79)
- Enhanced immune activity of cytotoxic T-lymphocyte epitope analogs derived from positional scanning synthetic combinatorial libraries. (2001) (79)
- Combinatorial chemistry: libraries from libraries, the art of the diversity-oriented transformation of resin-bound peptides and chiral polyamides to low molecular weight acyclic and heterocyclic compounds. (2004) (79)
- T cell multideterminant regions in the human immunodeficiency virus envelope: toward overcoming the problem of major histocompatibility complex restriction. (1989) (78)
- Immunogenicity. I. Use of peptide libraries to identify epitopes that activate clonotypic CD4+ T cells and induce T cell responses to native peptide ligands. (1999) (78)
- Human immune responses to synthetic peptides from the Epstein-Barr nuclear antigen. (1985) (77)
- Development of cross-reactive antibodies to plasminogen during the immune response to dengue virus infection. (1991) (76)
- Elucidation of discontinuous linear determinants in peptides. (1990) (75)
- Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis. (2005) (75)
- The antimicrobial activity of hexapeptides derived from synthetic combinatorial libraries. (1995) (74)
- Contribution of Individual Amino Acids Within MHC Molecule or Antigenic Peptide to TCR Ligand Potency1 (2000) (73)
- Induction of cytotoxic T cells to a cross-reactive epitope in the hepatitis C virus nonstructural RNA polymerase-like protein (1992) (72)
- HTS by NMR of combinatorial libraries: a fragment-based approach to ligand discovery. (2013) (72)
- Biochemical and pharmacological evidence for opioid receptor multiplicity in the central nervous system. (1983) (71)
- A review of the utility of soluble peptide combinatorial libraries (1995) (71)
- Minimal peptide length requirements for CD4(+) T cell clones--implications for molecular mimicry and T cell survival. (2000) (71)
- A Similarity‐based Data‐fusion Approach to the Visual Characterization and Comparison of Compound Databases (2007) (71)
- Selective Ligands for the μ, δ, and κ Opioid Receptors Identified from a Single Mixture Based Tetrapeptide Positional Scanning Combinatorial Library* (1998) (70)
- Generation and characterization of peptide-specific antibodies that inhibit von Willebrand factor binding to glycoprotein IIb-IIIa without interacting with other adhesive molecules. Selectivity is conferred by Pro1743 and other amino acid residues adjacent to the sequence Arg1744-Gly1745-Asp1746. (1988) (69)
- Autoantibody production in hepatitis B e antigen transgenic mice elicited with a self T-cell peptide and inhibited with nonself peptides. (1991) (69)
- Elucidation of a protease-sensitive site involved in the binding of calcium to C-reactive protein. (1989) (68)
- Effect of positional environmental domains on the variation of high-performance liquid chromatographic peptide retention coefficients. (1987) (68)
- Delineation of a cross-reactive idiotype on human autoantibodies with antibody against a synthetic peptide (1984) (68)
- Synthetic combinatorial libraries: novel discovery strategy for identification of antimicrobial agents (1996) (67)
- Identification of a β-endorphin-like peptide in cultured human placental cells (1982) (67)
- Combinatorial Libraries As a Tool for the Discovery of Novel, Broad-Spectrum Antibacterial Agents Targeting the ESKAPE Pathogens. (2015) (67)
- T and B cell responses of Plasmodium falciparum malaria-immune individuals to synthetic peptides corresponding to sequences in different regions of the P. falciparum antigen Pf155/RESA. (1989) (66)
- HLA-A2-restricted cytotoxic T lymphocyte responses to multiple Plasmodium falciparum sporozoite surface protein 2 epitopes in sporozoite-immunized volunteers. (1995) (66)
- T cell responses to cleaved rabies virus glycoprotein and to synthetic peptides. (1984) (66)
- Short Polybasic Peptide Sequences Are Potent Inhibitors of PC5/6 and PC7: Use of Positional Scanning-Synthetic Peptide Combinatorial Libraries as a Tool for the Optimization of Inhibitory Sequences (2007) (66)
- Anti-peptide antibodies detect oncogene-related proteins in urine. (1985) (65)
- Analysis of the epitopes of proliferating cell nuclear antigen recognized by monoclonal antibodies. (1993) (65)
- Identification of Inhibitors of Prohormone Convertases 1 and 2 Using a Peptide Combinatorial Library* (1998) (64)
- Identification of antimicrobial peptides by using combinatorial libraries made up of unnatural amino acids (1994) (64)
- Opiate binding in calf thalamic membranes: a selective mu 1 binding assay. (1988) (64)
- The degradation of dynorphin A in brain tissue in vivo and in vitro (1987) (63)
- Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen. (1994) (63)
- Combinatorial peptide libraries as an alternative approach to the identification of ligands for tumor-reactive cytolytic T lymphocytes. (2001) (63)
- Insights into native epitopes of proliferating cell nuclear antigen using recombinant DNA protein products (1990) (62)
- β-Endorphin: Characteristics of binding sites in the rat brain (1979) (62)
- High frequency of malaria‐specific T cells in non‐exposed humans (1992) (61)
- Influence of tryptophan residues on melittin's hemolytic activity. (1993) (60)
- Combinatorial chemistry: from peptides and peptidomimetics to small organic and heterocyclic compounds. (1998) (60)
- Simultaneous Multiple Peptide Synthesis: The Rapid Preparation of Large Numbers of Discrete Peptides for Biological, Immunological, and Methodological Studies (1987) (58)
- Formation of an Extremely Stable Polyalanine β-Sheet Macromolecule (1995) (57)
- Autoradiography of [3H]β-endorphin binding in brain (1983) (57)
- Characterization of human rheumatoid factors with seven antiidiotypes induced by synthetic hypervariable region peptides (1985) (57)
- Anti-hypervariable region antibody induced by a defined peptide: an approach for studying the structural correlates of idiotypes. (1984) (57)
- Multitarget Structure-Activity Relationships Characterized by Activity-Difference Maps and Consensus Similarity Measure (2011) (56)
- Location of human cytotoxic T cell epitopes within a polymorphic domain of the Plasmodium falciparum circumsporozoite protein. (1991) (56)
- Positional Scanning-Synthetic Peptide Library-Based Analysis of Self- and Pathogen-Derived Peptide Cross-Reactivity with Tumor-Reactive Melan-A-Specific CTL1 (2002) (56)
- Inhibition of a plant virus infection by analogs of melittin. (1995) (55)
- Epitopes of the Mycobacterium tuberculosis 65-kilodalton protein antigen as recognized by human T cells. (1988) (55)
- Versatility of positional scanning synthetic combinatorial libraries for the identification of individual compounds (1994) (53)
- Analysis of human T cell clones specific for conserved peptide sequences within malaria proteins. Paucity of clones responsive to intact parasites. (1994) (52)
- Solid phase synthesis of heterocyclic compounds from linear peptides: Cyclic ureas and thioureas (1997) (52)
- Localization of neutralizing regions of the envelope gene of feline leukemia virus by using anti-synthetic peptide antibodies (1987) (52)
- Parallel array and mixture-based synthetic combinatorial chemistry: tools for the next millennium. (2000) (51)
- Identification of Two Novel, Potent, Low-Liability Antinociceptive Compounds from the Direct In Vivo Screening of a Large Mixture-Based Combinatorial Library (2010) (51)
- Rapid identification of compounds with enhanced antimicrobial activity by using conformationally defined combinatorial libraries. (1996) (49)
- RGDV peptide selectively inhibits platelet-dependent thrombus formation in vivo. Studies using a baboon model. (1989) (48)
- Discovery of Novel Inhibitors of a Disintegrin and Metalloprotease 17 (ADAM17) Using Glycosylated and Non-glycosylated Substrates* (2012) (47)
- Development of two monoclonal antibodies against Plasmodium falciparum sporozoite surface protein 2 and mapping of B-cell epitopes (1997) (46)
- Secondary structure induction in aqueous vs membrane‐like environments (1997) (46)
- The Magainins: sequence factors relevant to increased antimicrobial activity and decreased hemolytic activity. (1988) (46)
- Functionalized Protein-like Structures from Conformationally Defined Synthetic Combinatorial Libraries (*) (1996) (46)
- Findings on T cell specificity revealed by synthetic combinatorial libraries. (2002) (45)
- Toward Targeted Oral Vaccine Delivery Systems: Selection of Lectin Mimetics from Combinatorial Libraries (2003) (45)
- Identification of a sequence of human activated protein C (residues 390-404) essential for its anticoagulant activity. (1991) (45)
- [3H]-beta-endorphin binding in rat brain (1984) (45)
- Immune activation in cervical neoplasia: cross-sectional association between plasma soluble interleukin 2 receptor levels and disease. (1997) (44)
- Solid phase synthesis of 1,3,4,7-Tetrasubstituted Perhydro-1,4-diazepine-2,5-diones (1997) (44)
- Major population differences in T cell response to a malaria sporozoite vaccine candidate. (1990) (44)
- Synthetic idiotypes: The third hypervariable region of murine anti-dextran antibodies (1983) (44)
- The use of synthetic peptide combinatorial libraries for the determination of peptide ligands in radio-receptor assays: Opioid peptides (1993) (44)
- Distinction between immunogenicity and tolerogenicity among HBcAg T cell determinants. Influence of peptide-MHC interaction. (1989) (44)
- Prodynorphin peptide immunocytochemistry in rhesus monkey brain (1985) (43)
- Selected peptides targeted to the NMDA receptor channel protect neurons from excitotoxic death (1998) (43)
- Vaccine for enterotoxigenic Escherichia coli based on synthetic heat-stable toxin crossed-linked to the B subunit of heat-labile toxin. (1983) (43)
- Activity of ADAM17 (a Disintegrin and Metalloprotease 17) Is Regulated by Its Noncatalytic Domains and Secondary Structure of its Substrates* (2013) (42)
- The Multi-Leu Peptide Inhibitor Discriminates Between PACE4 and Furin And Exhibits Antiproliferative Effects On Prostate Cancer Cells (2012) (42)
- A linear hexapeptide somatostatin antagonist blocks somatostatin activity in vitro and influences growth hormone release in rats. (1998) (42)
- A small molecule inhibitor of XIAP induces apoptosis and synergises with vinorelbine and cisplatin in NSCLC (2009) (42)
- Combinatorial peptide library‐based identification of peptide ligands for tumor‐reactive cytolytic T lymphocytes of unknown specificity (2002) (40)
- Small-molecule XIAP antagonist restores caspase-9 mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells. (2007) (40)
- Recombinant pseudorabies virus carrying a plasmodium gene: herpesvirus as a new live viral vector for inducing T- and B-cell immunity. (1992) (40)
- Cytotoxic T lymphocyte (CTL) low-responsiveness to the Plasmodium falciparum circumsporozoite protein in naturally-exposed endemic populations: analysis of human CTL response to most known variants. (1993) (39)
- The synthesis of peptidomimetic combinatorial libraries through successive amide alkylations. (1996) (39)
- A traceless approach for the parallel solid-phase synthesis of 2-(arylamino)quinazolinones. (2002) (38)
- Characterization of an epibody. An antiidiotype that reacts with both the idiotype of rheumatoid factors (RF) and the antigen recognized by RF (1985) (38)
- A Synthetic Combinatorial Strategy for Developing α-Conotoxin Analogs as Potent α7 Nicotinic Acetylcholine Receptor Antagonists* (2009) (38)
- Synthesis of 4-amino-3,4-dihydro-2(1H)-quinolinonesvia β-lactam intermediates on the solid-phase (1997) (38)
- Functional importance of amino acid residues making up peptide antigenic determinants. (1993) (37)
- Determination of the secondary structure of selected melittin analogues with different haemolytic activities. (1994) (37)
- Cyclic peptide template combinatorial libraries: synthesis and identification of chymotrypsin inhibitors. (1994) (37)
- Use of a synthetic peptide antigen to generate antisera reactive with a proteolytic processing site in native human proinsulin: demonstration of cleavage within clathrin-coated (pro)secretory vesicles. (1987) (37)
- IMMUNISATION OF VOLUNTEERS WITH A SYNTHETIC PEPTIDE VACCINE FOR ENTEROTOXIGENIC ESCHERICHIA COLI (1986) (36)
- Peptide libraries: criteria and trends. (1993) (35)
- CYCLOPEPTIDE ALKALOIDS. SYNTHESIS OF THE RING SYSTEM AND ITS ION AFFINITY (1978) (35)
- Conformation and dynamics of an Fab'-bound peptide by isotope-edited NMR spectroscopy. (1992) (35)
- Mapping of functional and antigenic domains of the alpha 4 protein of herpes simplex virus 1 (1988) (35)
- Human immunodeficiency virus reverse transcriptase T helper epitopes identified in mice and humans: correlation with a cytotoxic T cell epitope. (1991) (35)
- Solid-phase synthesis of linear ureas tethered to hydantoins and thiohydantoins. (2002) (34)
- Antibodies of predetermined specificity against chemically synthesized peptides of human interleukin 2. (1984) (34)
- Solid-phase synthesis of 1,5-disubstituted 2-aryliminoimidazolidines. (2002) (34)
- Inhibition of beta-amyloid-induced neurotoxicity by imidazopyridoindoles derived from a synthetic combinatorial library. (2000) (33)
- The use of soluble synthetic peptide combinatorial libraries to determine antigen recognition of T cells. (2009) (33)
- Binding of 3H-β-endorphin in rat brain (1982) (33)
- Synthesis of cyclic peptides through direct aminolysis of peptide thioesters catalyzed by imidazole in aqueous organic solutions. (2009) (32)
- Activation of bee venom phospholipase A2 through a peptide‐enzyme complex (1995) (32)
- Protection against human and porcine enterotoxigenic strains of Escherichia coli in rats immunized with a cross-linked toxoid vaccine (1983) (32)
- Preparation and properties of tritiated human beta-endorphin with high specific radioactivity. (2009) (32)
- Parallel solid phase synthesis of tetrasubstituted diethylenetriamines via selective amide alkylation and exhaustive reduction of N-acylated dipeptides (1999) (32)
- Detection of high molecular weight forms of platelet-derived growth factor by sequence-specific antisera. (1984) (31)
- Small-Molecule Inhibitors Targeting Topoisomerase I as Novel Antituberculosis Agents (2016) (31)
- Synthetic peptide combinatorial libraries (SPCLs): identification of the antigenic determinant of beta-endorphin recognized by monoclonal antibody 3E7. (1993) (31)
- Peptide, peptidomimetic, and organic synthetic combinatorial libraries (1995) (31)
- Improved, high yield synthesis of 3H-quinazolin-4-ones, the key intermediates of recently developed drugs. (2004) (31)
- Protection in rabbits immunized with a vaccine of Escherichia coli heat-stable toxin cross-linked to the heat-labile toxin B subunit (1983) (30)
- Increased Diversity of Libraries from Libraries: Chemoinformatic Analysis of Bis‐Diazacyclic Libraries (2011) (30)
- Properties of synthetically produced Escherichia coli heat-stable enterotoxin (1983) (30)
- Selective Agonists and Antagonists of Formylpeptide Receptors: Duplex Flow Cytometry and Mixture-Based Positional Scanning Libraries (2013) (30)
- Immunological properties of purified Klebsiella pneumoniae heat-stable enterotoxin (1983) (29)
- Enzyme-linked immunosorbent assay for Escherichia coli heat-stable enterotoxin (1984) (29)
- Human somatotropin. Reaction with hydrogen peroxide. (1977) (29)
- Chemical synthesis of an octadecapeptide with the biological and immunological properties of human heat-stable Escherichia coli enterotoxin. (1984) (29)
- Generation and use of nonsupport-bound peptide and peptidomimetic combinatorial libraries. (1996) (29)
- Scaffold ranking and positional scanning utilized in the discovery of nAChR-selective compounds suitable for optimization studies. (2013) (28)
- A chemically synthesized peptide which elicits humoral and cellular immune responses to mycobacterial antigens (1986) (28)
- The broad utility of soluble peptide libraries for drug discovery. (1993) (27)
- Modeling of peptides containing D-amino acids: implications on cyclization (2009) (26)
- A completely synthetic toxoid vaccine containing Escherichia coli heat-stable toxin and antigenic determinants of the heat-labile toxin B subunit (1985) (26)
- Discovery of a Potent and Selective α3β4 Nicotinic Acetylcholine Receptor Antagonist from an α-Conotoxin Synthetic Combinatorial Library (2014) (26)
- Parallel solid-phase synthesis of 2-imino-4-oxo-1,3,5-triazino[1,2-a]benzimidazoles via tandem aza-Wittig/heterocumulene-mediated annulation reaction. (2003) (25)
- Palladium-catalyzed C-H functionalization using guanidine as a directing group: ortho arylation and olefination of arylguanidines. (2012) (25)
- Human and murine CD4 T cell epitopes map to the same region of the malaria circumsporozoite protein: limited immunogenicity of sporozoites and circumsporozoite protein. (1988) (25)
- Tethered libraries: solid-phase synthesis of substituted urea-linked bicyclic guanidines. (2001) (25)
- Toward synthetic combinatorial peptide libraries in positional scanning format (PS-SCL)-based identification of CD8+ Tumor-reactive T-Cell Ligands: a comparative analysis of PS-SCL recognition by a single tumor-reactive CD8+ cytolytic T-lymphocyte clone. (2002) (25)
- Soluble combinatorial libraries of organic, peptidomimetic and peptide diversities (1995) (24)
- Identification of Inhibitors of Melittin Using Nonsupport-bound Combinatorial Libraries (*) (1996) (24)
- Perturbation of peptide conformations induced in anisotropic environments (1992) (24)
- Immunization with soluble protein-pulsed spleen cells induces class I-restricted cytotoxic T lymphocytes that recognize immunodominant epitopic peptides from Plasmodium falciparum and HIV-1. (1992) (24)
- Induction of murine cytotoxic T lymphocytes against Plasmodium falciparum sporozoite surface protein 2 (1994) (24)
- Solid-Phase Synthesis of Trisubstituted 2-Imidazolidones and 2-Imidazolidinethiones (1999) (24)
- Solid phase synthesis of 1,4-benzothiazepin-5-one derivatives (1999) (24)
- Functional identification of agretopic and epitopic residues within an HBcAg T cell determinant. (1989) (24)
- Mixture-Based Synthetic Combinatorial Libraries (1999) (23)
- Human major histocompatibility complex class I antigens: residues 61-83 of the HLA-B7 heavy chain specify an alloreactive site. (1985) (23)
- Synthetic compound peptide simulating antigenicity of conformation-dependent autoepitope. (1994) (23)
- Antibodies of predetermined specificity detect two retroviral oncogene products and inhibit their kinase activities. (1983) (23)
- Localization of the binding site for a factor VIII activity neutralizing antibody to amino acid residues Asp1663-Ser1669. (1988) (23)
- Solid-phase synthesis of 2,3,5-trisubstituted 4H-imidazolones. (2001) (23)
- Solid-phase synthesis of 5-aminotetrazoles (2004) (23)
- An N-methyl-d-aspartate receptor channel blocker with neuroprotective activity (2001) (22)
- Tools of the Trade Combinatorial Libraries: Finding the needle in the haystack (1994) (22)
- Solid-phase synthesis of alpha,alpha-difluoro-beta-amino acids via the Reformatsky reaction. (2001) (22)
- Solid-Phase Synthesis of Substituted 2,3-Diketopiperazines from Reduced Polyamides (2000) (22)
- Orphanin FQ/Nociceptin receptor binding studies (2000) (22)
- Identification of a Novel Polyamine Scaffold With Potent Efflux Pump Inhibition Activity Toward Multi-Drug Resistant Bacterial Pathogens (2018) (22)
- The Current Status of Heterocyclic Combinatorial Libraries (1997) (22)
- De novo identification of highly active fluorescent kappa opioid ligands from a rhodamine labeled tetrapeptide positional scanning library. (2004) (21)
- Effect of chronic exercise on beta-endorphin receptor levels in rats. (1986) (21)
- A Synthetic Factor VIII Peptide of Eight Amino Acid Residues (1677-1684) Contains the Binding Region of an Anti-Factor VIII Antibody which Inhibits the Binding of Factor VIII to von Willebrand Factor (1990) (21)
- SOLID PHASE SYNTHESIS OF 2,4,5-TRISUBSTITUTED THIOMORPHOLIN-3-ONES (1998) (21)
- Identification of Related Peptides Recognized by a Monoclonal Antibody Using a Synthetic Peptide Combinatorial Library (1992) (21)
- Efficient solid phase synthesis of 3,5-disubstituted hydantoins (1998) (21)
- Degradation of [3H]β-endorphin in rat plasma is increased with chronic stress (1989) (20)
- Studies on pituitary prolactin. 39. Reaction of the ovine hormone with hydrogen peroxide. (1976) (20)
- Mixture-Based Heterocyclic Combinatorial Positional Scanning Libraries: Discovery of Bicyclic Guanidines Having Potent Antifungal Activities against Candida albicans andCryptococcus neoformans (1999) (20)
- Parallel Synthesis of Hexahydrodiimidazodiazepines Heterocyclic Peptidomimetics and Their in Vitro and in Vivo Activities at μ (MOR), δ (DOR), and κ (KOR) Opioid Receptors. (2015) (20)
- Evaluation of peptide-peptide interactions using reversed-phase high-performance liquid chromatography. (1992) (20)
- A traceless approach to amide and peptide construction from thioacids and dithiocarbamate-terminal amines (2013) (20)
- The immune response to Epstein-Barr nuclear antigen: conformational and structural features of antibody binding to synthetic peptides. (1984) (19)
- Solid-phase synthesis of branched thiohydantoin benzimidazolinethiones and branched thiohydantoin tetrahydroquinoxalinediones (2000) (19)
- Use and implications of the harmonic mean model on mixtures for basic research and drug discovery. (2011) (19)
- A Novel Class of Common Docking Domain Inhibitors That Prevent ERK2 Activation and Substrate Phosphorylation. (2019) (19)
- Identification of Tetrapeptides from a Mixture Based Positional Scanning Library That Can Restore nM Full Agonist Function of the L106P, I69T, I102S, A219V, C271Y, and C271R Human Melanocortin-4 Polymorphic Receptors (hMC4Rs) (2014) (18)
- The Mathematics of a Successful Deconvolution: A Quantitative Assessment of Mixture-Based Combinatorial Libraries Screened Against Two Formylpeptide Receptors (2013) (18)
- Formation of an extremely stable polyalanine beta-sheet macromolecule. (1995) (18)
- Analysis of a subclass-restricted HIV-1 gp41 epitope by omission peptides. (1989) (18)
- Synthesis of cyclic disulfide peptides: comparison of oxidation methods (1997) (18)
- The chemistry of site-directed serology for HIV infections. (1989) (18)
- Novel α-glucosidase inhibitors identified using multiple cyclic peptide combinatorial libraries (1996) (18)
- Solid-phase synthesis of substituted imidazoline-tethered 2,3-diketopiperazines, cyclic ureas, and cyclic thioureas. (2001) (18)
- Solid-phase synthesis of bis-heterocyclic compounds from resin-bound orthogonally protected lysine. (2001) (18)
- Conformation-opioid activity relationships of bicyclic guanidines from 3D similarity analysis. (2008) (18)
- A study of human T-cell lines generated from multiple sclerosis patients and controls by stimulation with peptides of myelin basic protein (1996) (18)
- Synthesis of pure p-chlorophenyl-L-alanine from L-phenylalanine. (1974) (18)
- Parallel synthesis of chiral pentaamines and pyrrolidine containing bis-heterocyclic libraries. Multiple scaffolds with multiple building blocks: a double diversity for the identification of new antitubercular compounds. (2009) (18)
- Synthetic Small-Molecule Prohormone Convertase 2 Inhibitors (2009) (18)
- Rapid Scanning Structure-Activity Relationships in Combinatorial Data Sets: Identification of Activity Switches (2013) (17)
- Soluble Combinatorial Libraries: Extending the Range and Repertoire of Chemical Diversity (1994) (17)
- Glycosylation of a disintegrin and metalloprotease 17 affects its activity and inhibition. (2014) (17)
- Generation and utilization of synthetic combinatorial libraries. (1995) (17)
- Macrolactonization of peptide thioesters catalyzed by imidazole and its application in the synthesis of kahalalide B and analogues. (2010) (17)
- Dissociation of Antimicrobial and Hemolytic Activities of Gramicidin S through N‐Methylation Modification (2013) (17)
- Use of combinatorial library screening to identify inhibitors of a bacterial two-component signal transduction kinase (2004) (17)
- Probing the relationships between the structure and hemolytic activity of melittin with a complete set of leucine substitution analogs. (1991) (16)
- Synthesis and biological evaluations of novel endomorphin analogues containing α-hydroxy-β-phenylalanine (AHPBA) displaying mixed μ/δ opioid receptor agonist and δ opioid receptor antagonist activities. (2015) (16)
- The pharmacological properties of a novel MCH1 receptor antagonist isolated from combinatorial libraries. (2009) (16)
- "Volatilizable" supports for high-throughput organic synthesis. (2005) (16)
- An efficient approach for solid-phase synthesis of peptidomimetics based on 4-imidazolidinones (2002) (16)
- Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis (2016) (16)
- Synthetic peptide derived from the epstein‐barr virus encoded early diffuse antigen (ea‐d) reactive with human antibodies (1987) (16)
- A novel approach for solid-phase synthesis of substituted imidazolines and bis-imidazolines. (2001) (16)
- Use of 10% sulfuric acid/dioxane for removal of N‐α‐tertiary‐butyloxycarbonyl group during solid phase peptide synthesis (2009) (15)
- Peptide binding domains determined through chemical modification of the side-chain functional groups. (1995) (15)
- Binding of [3H]dynorphin A to apparent kappa opioid receptors in deep layers of guinea pig cerebral cortex. (1984) (15)
- Properties of cross-linked toxoid vaccines made with hyperantigenic forms of synthetic Escherichia coli heat-stable toxin (1984) (15)
- In vitro and direct in vivo testing of mixture-based combinatorial libraries for the identification of highly active and specific opiate ligands (2006) (15)
- Identification of a lymphocyte-activating pentapeptide sequence in the Fc region of human IgG1. (1987) (14)
- A murine monoclonal anti-factor VIII inhibitory antibody and two human factor VIII inhibitors bind to different areas within a twenty amino acid segment of the acidic region of factor VIII heavy chain. (1990) (14)
- Solid-phase synthesis of 1,2,5-trisubstituted 4-imidazolidinones. (2002) (14)
- SAR Studies of Exosite-Binding Substrate-Selective Inhibitors of A Disintegrin And Metalloprotease 17 (ADAM17) and Application as Selective in Vitro Probes. (2015) (14)
- Identification of Small Molecule Inhibitors of Human As(III) S-Adenosylmethionine Methyltransferase (AS3MT) (2015) (14)
- Differences in cross-protection in rats immunized with the B subunits of cholera toxin and Escherichia coli heat-labile toxin (1984) (14)
- [3H] dynorphin binding to guinea pig and rat brain. (1983) (13)
- Structural characterization and 5′‐mononucleotide binding of polyalanine β‐sheet complexes (1996) (13)
- The role of imidazole in peptide cyclization by transesterification: parallels to the catalytic triads of serine proteases. (2013) (13)
- Evidence that mammalian ribonucleotide reductase is a nuclear membrane associated glycoprotein. (1990) (13)
- Peptidic complex mixtures as therapeutic agents in CNS autoimmunity. (2004) (13)
- Solid phase synthesis of [3,5,7]-1H-imidazo[1,5-a]imidazol-2(3H)-ones (2001) (13)
- Solid-phase parallel synthesis of 2-aminoimidazolidin-4-ones (2002) (13)
- Solid-phase synthesis of bis-2-imidazolidinethiones from resin-bound tripeptides. (2000) (13)
- Novel approaches for the solid-phase synthesis of biheterocyclic dihydroimidazole analogues. (2002) (13)
- Immunochemistry of the dominating antigenic region Ala582 to Cys604 in the transmembranous protein of simian and human immunodeficiency virus. (1989) (13)
- Elucidation of monoclonal antibody polyspecificity using a synthetic combinatorial library. (1995) (13)
- Mucosal antitoxin response in volunteers to immunization with a synthetic peptide of Escherichia coli heat-stable enterotoxin (1985) (13)
- Solid-phase synthesis of indolines via palladium-catalyzed cyclization (2003) (13)
- Discovery of novel antinociceptive α-conotoxin analogues from the direct in vivo screening of a synthetic mixture-based combinatorial library. (2013) (12)
- Tea bag synthesis of positional scanning synthetic combinatorial libraries and their use for mapping antigenic determinants. (1996) (12)
- Anti-HLA antibodies of predetermined specificity: a chemically synthesized peptide induces antibodies specific for HLA-A,B heavy chain. (1983) (12)
- Comparison of 55% TFA/CH2Cl2 and 100% TFA for Boc group removal during solid-phase peptide synthesis. (2009) (12)
- Highly specific, cross-reactive sequences recognized by an anti-HBsAg antibody identified from a positional scanning synthetic combinatorial library. (1996) (12)
- Conditional Probabilistic Analysis for Prediction of the Activity Landscape and Relative Compound Activities (2013) (12)
- A novel approach for the solid-phase synthesis of substituted cyclic guanidines, their respective bis analogues, and N-acylated guanidines from N-acylated amino acid amides. (2001) (12)
- Abnormal aza-Wittig reaction on the solid-phase: chemoselectivity studies towards the parallel synthesis of 3-aryl-2,4-dioxo-1,3,5-triazino[1,2-a]benzimidazoles (2003) (12)
- Solid-phase synthesis of 1,7-disubstituted-1,3,5-triazepane-2,4-diones. (2001) (12)
- Ligand/kappa-opioid receptor interactions: insights from the X-ray crystal structure. (2013) (12)
- Libraries from libraries: Generation and comparison of screening profiles (1996) (12)
- A traceless approach for the solid-phase synthesis of 6-amino-1,3,5-triazine-2,4-diones. (2004) (11)
- An efficient two-step synthesis of mono-, di- and triureas from resin-bound amides (2000) (11)
- Scaffold approach for solid-phase synthesis of 2,3-disubstituted 8-arylamino-3H-imidazo[4,5-g]quinazolines. (2007) (11)
- IDENTIFICATION OF MU-SELECTIVE POLYAMINE ANTAGONISTS FROM A SYNTHETIC COMBINATORIAL LIBRARY (1995) (11)
- Identification of novel small-molecule Ulex europaeus I mimetics for targeted drug delivery. (2003) (11)
- Chapter 17. Progress in Antimicrobial Peptides (1992) (11)
- Enzyme linked immunosorbent assay (ELISA) for β-endorphin and its antibodies (1983) (11)
- Identification, structure-activity relationships and molecular modeling of potent triamine and piperazine opioid ligands. (2009) (11)
- Conformational landscape of platinum(II)-tetraamine complexes: DFT and NBO studies (2010) (11)
- Reduction of sulfoxides in peptides and proteins. (1979) (11)
- Solid-phase parallel synthesis of trisubstituted dihydroimidazolyl dihydroquinoxalin-2(1H)-ones (2002) (11)
- Identification of potent and highly selective chiral tri-amine and tetra-amine mu opioid receptors ligands: an example of lead optimization using mixture-based libraries. (2006) (11)
- Immunologic and functional characterization of anti-HLA-DR rabbit antibodies induced by synthetic peptides. (1984) (11)
- Mapping the detailed specificity of a calcium-dependent monoclonal antibody through the use of soluble positional scanning combinatorial libraries: Identification of potent calcium-independent antigens (1995) (11)
- Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2. (2017) (11)
- Determination of isokinetic ratios necessary for equimolar incorporation of carboxylic acids in the solid-phase synthesis of mixture-based combinatorial libraries. (2002) (11)
- Inclusion volume solid‐phase synthesis (1996) (11)
- A traceless approach for the solid-phase parallel synthesis of trisubstituted oxindoles. (2007) (11)
- A Novel Probe for Spliceosomal Proteins that Induces Autophagy and Death of Melanoma Cells Reveals New Targets for Melanoma Drug Discovery (2020) (11)
- The Systematic Development of Peptides Having Potent Antimicrobial Activity Against E. coli Through the Use of Synthetic Peptide Combinatorial Libraries (1993) (11)
- Opioid activity of 4-imidazolidinone positional analogues of Leu-Enkephalin. (2002) (11)
- Solid-phase synthesis of skeletally diverse benzofused sultams via palladium-catalyzed cyclization (2011) (11)
- Halogenoalkyl isocyanates as bifunctional reagents in an Aza-Wittig/heterocyclization reaction on the solid phase: efficient entry into new tetracyclic benzimidazole systems. (2004) (10)
- Peptide immunization can elicit malaria protein-specific memory helper but not proliferative T cells. (1990) (10)
- Studies on the reaction between human growth hormone and oleic acid using polyacrylamide gel electrophoresis. (1979) (10)
- Comparison of the binding of α‐helical and β‐sheet peptides to a hydrophobic surface (2009) (10)
- Solid-phase synthesis of 3-amino-1,2,4-triazoles (2003) (10)
- A comparison of combinatorial library approaches for the study of opioid compounds (1995) (10)
- Solid phase synthesis of mixture-based acyclic and heterocyclic small molecule combinatorial libraries from resin-bound polyamides. (2001) (10)
- Parallel synthesis of 4,5-dihydro-1H-1,4-benzodiazepine-2,3-diones (2001) (10)
- Human beta-endorphin: synthesis and characterization of analogs iodinated and tritiated at tyrosine residues 1 and 27. (1980) (10)
- alpha-Neo-endorphin: receptor binding properties of the tritiated ligand. (1983) (10)
- Discovery of novel peptidic dopamine transporter ligands by screening a positional scanning combinatorial hexapeptide library (1999) (10)
- Mixture-based combinatorial libraries: from peptides and peptidomimetics to small molecule acyclic and heterocyclic compounds. (2003) (10)
- A novel method for the determination of isokinetic ratios and its application in the synthesis of two new positional scanning libraries. (2012) (10)
- Identification of a nonameric H-2Kk-restricted CD8+ cytotoxic T lymphocyte epitope on the Plasmodium falciparum circumsporozoite protein (1995) (9)
- Solid phase synthesis of 1,6-disubstituted 2,3-diketopiperazines and 1,2-disubstituted piperazines from N-acylated amino acids (1999) (9)
- A CTL epitope on the circumsporozoite protein of P. yoelii. (1990) (9)
- Bicyclic guanidino ketones (1979) (9)
- All D‐amino acid hexapeptide inhibitors of melittin's cytolytic activity derived from synthetic combinatorial libraries (1996) (9)
- Parallel solid-phase synthesis of trisubstituted triazinobenzimidazolediones. (2002) (9)
- Solid-phase synthesis of bis-cyclic guanidines from tripeptides (2001) (9)
- Efficient solid-phase synthesis of 1,3,5-trisubstituted 1,3,5-triazine-2,4,6-triones. (2002) (9)
- From rapid In Vitro screening to rapid In Vivo screening in the drug discovery process (2009) (9)
- Identification of 5,6-dihydroimidazo[2,1-b]thiazoles as a new class of antimicrobial agents. (2016) (9)
- Integrating computational and mixture-based screening of combinatorial libraries (2011) (9)
- Highly Selective and Potent α4β2 nAChR Antagonist Inhibits Nicotine Self-Administration and Reinstatement in Rats. (2017) (9)
- Polyalkylamine chemical combinatorial libraries (1995) (9)
- High throughput synthesis of peptide alpha-thioesters through the use of "volatilizable" support. (2008) (9)
- Identification of novel antitumor agents from mixture-based synthetic combinatorial libraries using cell-based assays (1998) (8)
- Identification of B Cell and T Cell Epitopes Using Synthetic Peptide Combinatorial Libraries (2001) (8)
- Affinity purification of β-endorphin-like material from NG108CC15 hybrid cells by means of the monoclonal β-endorphin antibody 3-E7 (1985) (8)
- Solid phase synthesis of 1,3-disubstituted succinimides (2000) (8)
- Scaffold Ranking and Positional Scanning Identify Novel Neurite Outgrowth Promoters with Nanomolar Potency. (2018) (8)
- An expedient method for the solid-phase synthesis of α-aminoalkyl phosphonopeptides (2002) (8)
- Exploring the chemical space of peptides for drug discovery: a focus on linear and cyclic penta-peptides (2018) (8)
- Synthetic peptides from P. falciparum sexual stage 25-kDa protein induce antibodies that react with the native protein: the role of IL-2 and conformational structure on immunogenicity of Pfs25. (1995) (8)
- Reaction of ovine prolactin with 2-(2-nitrophenylsulfenyl)-3-methyl-3'-bromoindolemine. (2009) (8)
- Solid-phase parallel synthesis of substituted dihydroimidazolyl dihydrobenzimidazol-2-ones (2002) (8)
- Identification of a Small Molecule That Selectively Inhibits Mouse PC2 over Mouse PC1/3: A Computational and Experimental Study (2013) (7)
- Identification of B Cell and T Cell Epitopes Using Synthetic Peptide Combinatorial Libraries (2001) (7)
- Anomalous reversed-phase high-performance liquid chromatographic behavior of synthetic peptides related to antigenic helper T cell sites. (1992) (7)
- Separation of inorganic isomers by thin-layer chromatography : VI. Isomers of the non-metals boron, phosphorus and silica (1976) (7)
- Synthetic peptides as binding-step based catalytic mimics. (1994) (7)
- Potent μ-Opioid Receptor Agonists from Cyclic Peptides Tyr-c[D-Lys-Xxx-Tyr-Gly]: Synthesis, Biological, and Structural Evaluation. (2016) (7)
- Characterization of a helper T cell epitope recognized by mice of a low responder major histocompatibility type. (1990) (7)
- Reaction of human choriomammotropin with hydrogen peroxide. (1977) (7)
- Solid-Phase Synthesis, Characterization, and Screening of a 43,000- Compound Tetrahydroisoquinoline Combinatorial Library. (1997) (7)
- High Throughput Synthesis of 2,3,6-Trisubstituted-5,6-Dihydroimidazo[2,1-b]thiazole Derivatives. (2011) (7)
- Peptides: the wave of the future : proceedings of the second International and the seventeenth American Peptide Symposium, June 9-14, 2001, San Diego, California, U.S.A. (2001) (7)
- Solid phase synthesis of 3,4,7-trisubstituted 4,5,8,9-tetrahydro-3H-imidazo[1,2-a][1,3,5]triazepin-2(7H)-thiones and N-alkyl-4,5,7,8-tetrahydro-3H-imidazo[1,2-a][1,3,5]triazepin-2-amines. (2006) (7)
- The combined solid/solution-phase synthesis of nitrosamines: the evolution of the "libraries from libraries" concept. (2003) (6)
- Peptidomimetic synthetic combinatorial libraries (1997) (6)
- Autoradiography of [3H]beta-endorphin binding in brain. (1983) (6)
- Solid phase synthesis of styrylquinazolinones (2000) (6)
- Fluorescent mu selective opioid ligands from a mixture based cyclic peptide library. (2012) (6)
- Parallel solid-phase synthesis of disubstituted 1,6-piperazine-2-ones. (2002) (6)
- Identification of a Hit Series of Antileishmanial Compounds through the Use of Mixture-Based Libraries. (2017) (6)
- Traceless Approach for the Synthesis of 3,5-Disubstituted Thiohydantoins on Functionalized Ionic-Liquid Support (2010) (6)
- Solid phase synthesis of 1-substituted pyroglutamates (2000) (6)
- Assessment of human cytotoxic T cell activity using synthetic peptides: potential for field application. (1991) (6)
- Mobility and evolutionary variability factors in protein antigenicity (reply) (1985) (6)
- Site-directed antisera to the chromophore binding site of phytochrome: characterization and cross-reactivity. (1986) (5)
- Solid-phase synthesis of 2-alkylidene-6-alkyl-imidazo[2,1-b]thiazole-3,5[2H,6H]-dione derivatives (2009) (5)
- Induction of human B cell differentiation by Fc region activators. I. Identification of an active tetrapeptide. (1989) (5)
- Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734 821 Pyrrolidine Bis-piperazines (2015) (5)
- An evaluation of the advantages and effectiveness of picric acid monitoring during solid phase peptide synthesis. (1990) (5)
- Is automated peptide synthesis slowing the advance of biomedical research (1987) (5)
- Use of Vilsmeier reagent for the solid-phase synthesis of 1,5-disubstituted 4,5-dihydro-1H-imidazoles and disubstituted 4,5-dihydro-1H-imidazolylbenzimidazoles. (2002) (5)
- Traceless solid-phase synthesis of N-substituted 3,5-bis(substituted-idene)piperidin-4-one derivatives (2010) (5)
- Identification of a beta-endorphin-like peptide in cultured human placental cells. (1982) (5)
- Synthesis of platinum(II) chiral tetraamine coordination complexes. (2006) (5)
- Preparative isotachophoresis on polyacrylamide gels: resolution as a function of time and wattage. (1977) (5)
- Toleration of amino acid substitutions within hepatitis B virus envelope protein epitopes established by peptide replacement set analysis. II. Region S(122-136). (1992) (5)
- Characterization of antigen-antibody interactions using single substitution analogs and mixture-based synthetic combinatorial libraries. (2009) (5)
- Novel alpha-glucosidase inhibitors identified using multiple cyclic peptide combinatorial libraries. (1996) (5)
- Discovery of Polypharmacological Melanocortin-3 and -4 Receptor Probes and Identification of a 100-Fold Selective nM MC3R Agonist versus a μM MC4R Partial Agonist. (2019) (5)
- Peralkylation. "Libraries from libraries": chemical transformation of synthetic combinatorial libraries. (1998) (5)
- Molecular diversity comes of age ! (1995) (4)
- One-pot high-throughput synthesis of beta-turn cyclic peptidomimetics via "volatilizable" supports. (2009) (4)
- Isolation and properties of two fragments from plasmin digests of human choriomammotropin. (2009) (4)
- Peripheral kappa opioid receptor activation drives cold hypersensitivity in mice (2020) (4)
- Selective cleavage at the single tryptophan residue in bovine somatotropin by 2-(2-nitrophenylsulfenyl)-3-methyl-3' -bromoindolemine. (2009) (4)
- Modified solid-phase methods for the rapid synthesis of opioid peptides. (2010) (4)
- Novel Pyrrolidine Diketopiperazines Selectively Inhibit Melanoma Cells via Induction of Late-Onset Apoptosis (2014) (4)
- Novel peripheral peptidic kappa agonists (1999) (4)
- Analyses of human rheumatoid factors with anti-idiotypes induced by synthetic peptides. (1987) (4)
- Generation and Characterization of Peptide-specific Antibodies That Inhibit Von Willebrand Factor Binding to Glycoprotein IIb-IIIa without Interacting with Other Adhesive Molecules (2001) (4)
- Combinatorial Chemistry: Libraries from Libraries, the Art of the Diversity‐Oriented Transformation of Resin‐Bound Peptides and Chiral Polyamides to Low Molecular Weight Acyclic and Heterocyclic Compounds (2004) (4)
- CHARACTERIZATION OF A HIGH AFFINITY 3H-βh-ENDORPHIN RECEPTOR IN RAT BRAIN CRUDE SYNAPTOSOMAL FRACTION (1980) (4)
- Palladium-Catalyzed C—H Functionalization Using Guanidine as a Directing Group: ortho-Arylation and Olefination of Arylguanidines. (2013) (4)
- Endorphin : Stability , clearance behavior , and entry into the central nervous system after intravenous injection of the tritiated peptide in rats and rabbits (4)
- HUMAN β‐ENDORPHIN: SYNTHESIS AND CHARACTERIZATION OF ANALOGS IODINATED AND TRITIATED AT TRYOSINE RESIDUES 1 AND 27 (2009) (4)
- Inhibition of melittin’s hemolytic activity using synthetic peptide combinatorial libraries (1993) (4)
- Two antipeptide monoclonal antibodies that recognize adhesive sequences in fibrinogen: identification of antigenic determinants and unrelated sequences using synthetic combinatorial libraries. (1995) (4)
- Specificity of Rabbit Antibodies Elicited by Related Synthetic Peptides (1986) (4)
- Solid-phase synthesis of N-substituted 3,4-dihydroquinazolinone derivatives (2011) (4)
- Identification of Linear HLA Class II Amino Acid Sequences Recognized by Rabbit Antisera against Native Molecules (1987) (3)
- A Comparative Study of BOP as a Coupling Agent Using Simultaneous Multiple Peptide Synthesis (1994) (3)
- Membrane Protecting Sequences and New Antimicrobial Peptides Identified through the Screening of Synthetic Peptide Combinatorial Libraries (1994) (3)
- The Antigenic Structure of the Rabies Virus Glycoprotein (1985) (3)
- Extending the range of molecular diversity through amide alkylation of peptide libraries (1995) (3)
- Novel Antifungal Compounds Derived from Heterocyclic Positional Scanning Combinatorial Libraries (1999) (3)
- Optimal peptide length determination using synthetic peptide combinatorial libraries (1994) (3)
- Preparation of synthetic peptide combinatorial libraries on cotton carriers and their application to the identification of trypsin inhibitors (1993) (3)
- Identification of an antigenic determinant for the surface antigen of hepatitis B virus using peptide libraries (1994) (3)
- Solid-phase parallel synthesis of substituted dihydroimidazolylbutyl dihydroimidazol-3-ium salts (2002) (3)
- The Versatility of Nonsupport‐Bound Combinatorial Libraries (2007) (3)
- Soluble Combinatorial Libraries of Peptides, Peptidomimetics, and Organics: Fundamental Tools for Basic Research and Drug Discovery (1999) (3)
- Exploring antibody polyspecificity using synthetic combinatorial libraries (1996) (3)
- Solid-phase synthesis of 2,3,4,5-tetrahydro-1 H-benzo[ e][1,4]diazepine derivatives (2011) (3)
- Binding of 3H-beta-endorphin in rat brain. (1982) (3)
- Rabbit Antipeptide Antibodies against Restricted Domains of the Histocompatibility Complex (1984) (3)
- Small-Molecule XIAP Inhibitors Derepress Downstream Effector Caspases and Induce Apoptosis of Leukemia Cell Lines and Patient Samples. (2004) (3)
- Solid‐phase synthesis of 4,8‐disubstituted‐8,9‐dihydropyrazino[2,3‐g]quinazolin‐7(6H)‐ones (2008) (3)
- A one-pot multicomponent approach to a new series of morphine derivatives and their biological evaluation. (2017) (2)
- Detailed studies of antibody specificity using synthetic peptide combinatorial libraries (1995) (2)
- Soluble Chemical Combinatorial Libraries: Current Capabilities and Future Possibilities (1996) (2)
- Identi fi cation of Small Molecule Inhibitors of Human As ( III ) S ‐ Adenosylmethionine Methyltransferase ( AS 3 MT ) (2019) (2)
- IDENTIFICATION OF FOLDED STRUCTURES IN IMMUNOGENIC PEPTIDES BY 2D NMR SPECTROSCOPY (1987) (2)
- Positional scanning synthetic peptide combinatorial libraries (1993) (2)
- Manual Multiple Synthesis Methods (2000) (2)
- Crystal structure of deltakephalin: a delta-selective opioid peptide with a novel beta-bend-like conformation. (1994) (2)
- Recognition of HLA Class II Molecules by Antipeptide Antibodies Elicited by Synthetic Peptides Selected from Regions of HLA-DP Antigens (1987) (2)
- Tritiated porcine dynorphin (1-17): synthesis and characterization. (1982) (2)
- Syntheses and titrations of unknown acids: A general chemistry laboratory experiment (1967) (2)
- Libraries from libraries: The generation of peptidomimetic combinatorial diversities (1995) (2)
- 1 Soluble Synthetic Combinatorial Libraries: The Use of Molecular Diversities for Drug Discovery (1996) (2)
- Comparison of structural and functional approaches for the study of peptide-mAb interactions (1992) (2)
- Solid-Phase Synthesis of 2,3,5,6-Tetrahydro-1H-imidazo[1,2-a]benzo[d]-[1,3]diazepinesvia Pd(OAc)2/Cu(OAc)2-CocatalyzedCyclization (2011) (2)
- Solid‐Phase Synthesis of Heterocycles from Peptides and Amino Acids (2011) (2)
- Antagonists of IAP-family anti-apoptotic proteins - Probe 2 (2010) (2)
- Comparison of the binding of alpha-helical and beta-sheet peptides to a hydrophobic surface. (1998) (2)
- Induced conformations of peptides during RPHPLC: Positional dependence of methionine oxidation (1991) (2)
- Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput "Unbiased" Screening Campaign. (2021) (2)
- 10 – Soluble Chemical Combinatorial Libraries: Current Capabilities and Future Possibilities (1995) (2)
- Design of conformationally defined combinatorial libraries (1995) (2)
- Structural characterization and 5'-mononucleotide binding of polyalanine beta-sheet complexes. (1996) (2)
- Measurement of Phagocytosis, Phagosome Acidification, and Intracellular Killing of Staphylococcus aureus (2012) (2)
- Enzyme Linked Immunosorbent Assay (ELISA) for -endorphin and its antibodies (1986) (2)
- The use of a peptide library composed of 34 012 224 hexamers for basic research and drug discovery (1992) (1)
- Title : Mu-Opioid receptor-biased ligands : safe , pain-free analgesics (2017) (1)
- Study of peptide-antibody interactions using a decapeptide positional scanning library (1995) (1)
- Advances in the Use of Synthetic Combinatorial Chemistry: Mixture‐Based Libraries (2003) (1)
- Multideterminant regions of the HIV-1 envelope with sites seen by murine and human helper T cells: circumventing the MHC restriction problem (1990) (1)
- Combinatorial chemistry: Solid-phase synthesis of heterocyclic compounds from C α -functionalized amino acids (2002) (1)
- Inhibition of XIAP Enhances Specific Cytotoxic T Lymphocyte (CTL) Killing and CD20-Directed Antibody-Dependent Cellular Cytotoxicity of Chronic Lymphocytic Leukemia B Cells. (2004) (1)
- Multiple epitope specificity of monoclonal antibodies to a single synthetic peptide: use in the characterization of the GP IIb-IIIa binding domain of von Willebrand factor. (1990) (1)
- Crystal structure of deltakephalin: a γ‐selective opioid peptide with a novel β‐bend‐like conformation (2009) (1)
- A Facile Approach to the Synthesis of 3,4-Disubstituted-2-Aminothiazolium Derivatives through the Use of A "Volatilizable" Support. (2010) (1)
- ISOLATION OF α-MELANOTROPIN AND N, O-DIACETYLSERINE1-α-MELANOTROPIN FROM PORCINE PITUITARY EXTRACTS (2009) (1)
- Libraries from Libraries: A Series of Sulfonamide Linked Heterocycles Derived from the Same Scaffold. (2013) (1)
- Selection by site-directed antibodies of small regions of peptides which are ordered in water. (2007) (1)
- Tetrakis(Pyridine)Silver(2+)Peroxydisulfate (2007) (1)
- A chemically synthesized peptide with mycobacterial characteristics (1987) (1)
- Peptides as precursors in the synthesis of heterocyclic positional scanning combinatorial libraries (2002) (1)
- Synthetic Combinatorial Libraries: A New Tool for Antimicrobial Agent Discovery (2000) (1)
- Combinatorial libraries: Equimolar incorporation of benzaldehyde mixtures in reductive alkylation reactions (2002) (1)
- Peptide-monoclonal antibody interactions defined at the amino acid level: Advantages of competitive ELISA techniques (1991) (1)
- Functional Mixture-Based Positional Scan Identifies a Library of Antagonist Tetrapeptide Sequences (LAtTeS) with Nanomolar Potency for the Melanocortin-4 Receptor and Equipotent with the Endogenous AGRP(86-132) Antagonist. (2021) (1)
- Identification of B Cell and T Cell Epitopes Using Synthetic Peptide Combinatorial Libraries (2022) (1)
- A Robust and Cost-Effective Luminescent-Based High-Throughput Assay for Fructose-1,6-Bisphosphate Aldolase A (2020) (1)
- Solid-phase synthesis of 3-alkyl-8-arylamino-1H-imidazo[4,5-g]quinazolin-2(3H)-thiones and 3-alkyl-8-arylamino-1H-imidazo[4,5-g]quinazolin-2(3H)-ones (2007) (1)
- Parallel synthesis of 1,6-disubstituted-1,2,4-triazin-3-ones on solid-phase. (2013) (1)
- A large scale classification of molecular fingerprints for the chemical space representation and SAR analysis (2012) (1)
- A priori determination of peptide ligands for opiate receptors using synthetic peptide combinatorial libraries (1993) (1)
- Antipeptide Antibodies: Do They Distinguish HLA-Alloantigens? (1986) (1)
- Generation of rabbit antipeptide antibodies to HLA-class II antigens by the use of synthetic peptides. (1988) (1)
- The theory and practice of combinatorial chemistry (1995) (1)
- Novel Cyclic Lipopeptides Fusaricidin Analogs for Treating Wound Infections (2021) (1)
- Rapidly Expanding Molecular Diversity: Libraries from Libraries (1998) (1)
- Enzyme linked immunosorbent assay (ELISA) for beta-endorphin and its antibodies. (1986) (1)
- Synthesis and Screening of Positional Scanning Synthetic Combinatorial Libraries (2001) (1)
- The effect of induced conformation on antimicrobial and hemolytic activity of amphipathic peptides (1991) (1)
- TETRAKIS(PYRIDINE)SILVER(2+)PEROXYDISULFATE : 2AGNO3 + 8C5H5N + 3K2S2S8 2AG(C5H5N)4S2O8 + 2K2SO4 + 2KNO3 (1998) (1)
- The determination of the precise amino acids involved, and their relative importance, in peptide antigen/monoclonal antibody interactions (1988) (1)
- beta-Endorphin: characteristics of binding sites in the rat brain. (1979) (1)
- The genome-linked proteins of aphthoviruses: specific immunoprecipitation of the three species detected on virus RNA and identification of possible precursors. (1986) (1)
- Degradation of [3H]beta-endorphin in rat plasma is increased with chronic stress. (1989) (1)
- Activity-difference maps and consensus similarity measure characterize structure-activity relationships (2012) (1)
- Simultaneous Multiple Peptide Synthesis: The Rapid Preparation of Large Numbers of Peptides (1987) (1)
- Generation of Peralkylated Peptidomimetic Combinatorial Libraries (1997) (1)
- SYNTHESIS OF PURE P-CHLOROPHENYL-L-ALANINE FROM L-PHENYLALANINE (1974) (1)
- Solid-Phase Synthesis of α-Difluoro-β-amino Acids by a Reformatsky Reaction (2001) (1)
- Combinatorial chemistry: mixture-based combinatorial libraries of acyclic and heterocyclic compounds from amino acids and short peptides. (2003) (1)
- Exploring the chemical space of peptides for drug discovery: a focus on linear and cyclic penta-peptides (2018) (0)
- Sequence Homology Identification of Agonist Ligands with No Recognition Based on Peptide Scans Leads to the Cutting Edge: Predictable TCR Antigen (1998) (0)
- Parallel Array and Mixture-Based Synthetic Combinatorial Chemistry: Tools for the Next Millennium (2000) (0)
- PREPARATION OF [3,5,7] -1H-imidazo [1,5-a] imidazole-2 (3H) -one compounds (2000) (0)
- Solid-Phase Synthesis of Heterocyclic Compounds from Amino Acids and Linear Peptides (2001) (0)
- Cyclic peptide template synthetic combinatorial libraries (1995) (0)
- United States Patent ( 19 ) Houghten 54 MEANS FOR SEQUENTIAL (2017) (0)
- Antibodies of predetermined -specif oncogene products. and inhibit thei) (2016) (0)
- High-throughput parallel synthesis of 3,4-disubstituted 1-(ω-hydroxyalkyl) imidazolin-2-ones on ‘volatilizable’ supports (2008) (0)
- 427 POSTER Preclinical development of xiapuradamib therapy for lung cancer (2006) (0)
- Determination of multiple binding specificities of a monoclonal antibody using a synthetic peptide combinatorial library (1993) (0)
- A BINDS SELECTIVELY TO GUINEA PIG BRAIN (2002) (0)
- to Native Peptide Ligands T Cells and Induce T Cell Responses + CD4 Clonotypic to Identify Epitopes That Activate Immunogenicity. I. Use of Peptide Libraries (1999) (0)
- Table 5, Submission of Probe and analogs (2011) (0)
- HIV-1gp4lepitope byomission peptides (1989) (0)
- Table 3, Binding affinity to the XIAP-BIR1/2 and BIR3 domains for representative examples (2011) (0)
- PREPARATION OF i3,5,7ö-1H-IMIDAZOi1,5-AöIMIDAZOL-2 (3H) -one compounds (2000) (0)
- Identification and optimization of antigens for T cell clones of clinical relevance using positional scanning combinatorial libraries (2002) (0)
- Silica-Phase Synthesis of Kahalalide B and Its Analogues (2010) (0)
- Electromagnetic Measurements, Operation TEAPOT. (1957) (0)
- Synthesis of equimolar multiple oligomeric mixtures, in particular of oligopeptide mixtures (1991) (0)
- Cytokine regulating agents and methods for their use in pathology and conditions associated with varying levels of cytokines (1996) (0)
- Polyamines as Intermediates for the Synthesis of Heterocyclic Compounds and Oligomeric Heterocyclic Compounds from Resin-Bound Polyamides (2001) (0)
- Traceless Approach for the Synthesis of 3,5‐Disubstituted Thiohydantoins on Functionalized Ionic‐Liquid Support. (2010) (0)
- Patent Number : ( 45 ) Date of Patent : 5 , 182 , 366 Jan . 26 , 1993 (2017) (0)
- AFFINITY PURIFICATION OF f 3-ENDORPHIN-LIKE MATERIAL FROM NGI 08 CC 15 HYBRID CELLS BY MEANS OF THE MONOCLONAL f 3-ENDORPHIN ANTIBODY 3E 7 (2009) (0)
- AnEpitope inHepatitis C Virus CoreRegion Recognized by Cytotoxic T Cells inMiceandHumans (1994) (0)
- Immuneresponsetouncoupled peptides of foot-and-mouth disease virus (1987) (0)
- New opioid peptide, selective for kappa receptor (1996) (0)
- 491 POSTER Trageting XIAP in paediatric cancers (2006) (0)
- Patent Number : 5 , 786 , 448 45 ) Date of Patent : Jul . 28 , 1998 (2017) (0)
- Table of Contents (1988) (0)
- Figure 1, Key SAR for our first library (2011) (0)
- Novel D-amino acid hexapeptide calmodulin antagonists identified from synthetic combinatorial libraries (2002) (0)
- Synthetic combinatorial libraries for the study of molecular mimicry: Identification of an all D-amino acid peptide recognized by an anti-carbohydrate antibody (2002) (0)
- Solid Phase Synthesis of 1,2,5-Substituted Derivatives of 4-Imidazolidinone (2001) (0)
- Lymphocytaktiverende polypeptides and their use (1987) (0)
- Solid-Phase Synthesis of 3,4-Dihydroquin-azolinones (2011) (0)
- An Efficient Solid-Phase Synthesis of Quinazoline Derivatives (2007) (0)
- Mixture-Based Combinatorial Libraries: from Peptides and Peptidomimetics to Small Molecule Acyclic and Heterocyclic Compounds (2005) (0)
- Peptides that inhibit von Willebrand Factor binding to the platelet SPIB receptor (1994) (0)
- to TCR Ligand Potency Within MHC Molecule or Antigenic Peptide Contribution of Individual Amino Acids (1999) (0)
- Solid-Phase Synthesis of Substituted Dihydroimidazoles and Their Bis Analogs (2001) (0)
- Rapid parallel synthesis of 584 betides, peptides composed largely of beta-amino acids with side-chains not found in natural peptides (2002) (0)
- Synthesis of equimolar mixtures vielzähliger oligomeric, especially oligopeptide (1991) (0)
- Solid-Phase Synthesis of Mixture-Based Acyclic and Heterocyclic Small Molecule Combinatorial Libraries from Resin-Bound Polyamides. (2002) (0)
- The relationship between potential induced conformation of melittin and its hemolytic activity (1992) (0)
- Determination of antigenic binding sites in antibodies directed against a mycobacterial peptide by deletion and substitution of single amino acids. (1989) (0)
- WT ERK2 with compound 2507-8 (2019) (0)
- Assay of anti-Epstein-Barr virus nuclear antigen antibodies with synthetic polypeptides (1990) (0)
- Solid-Phase Synthesis of Tetrahydrobenzo-diazepine Derivatives (2011) (0)
- Inhibition of XIAP Renders Newly CD40-Activated Chronic Lymphocytic Leukemia Cells Sensitive to Fas (CD95) Mediated Apoptosis. (2004) (0)
- Glycosylation of A Disintegrin And Metalloprotease 17 (ADAM17) Affects its Activity and Inhibition (2015) (0)
- Synthesis and Screening of Positional Scanning Combinatorial Libraries (1998) (0)
- Synthesis of cyclic ureas and cyclic thioureas from acyl dipeptides (2002) (0)
- First Japanese Conference on Combinatorial Chemistry and High Throughput Screening (1997) (0)
- Deletion analogs of magaininpeptiden. (1989) (0)
- United States Patent 19 Blondelle et al . ( 54 ) PEPTIDES OF THE FORMULA ( KFMOC ) ZZZ AND THEIR USES (2017) (0)
- Strategies for the Use of Mixture‐Based Synthetic Combinatorial Libraries: Scaffold Ranking, Direct Testing in vivo, and Enhanced Deconvolution by Computational Methods. (2008) (0)
- Isolation of alpha-melanotropin and N, O-diacetylserine1-alpha-melanotropin from porcine pituitary extracts. (1981) (0)
- Table 8, Summary of in vitro ADMET/PK Properties of West Nile Virus Inhibitor Probes (2011) (0)
- Running title : Small molecule PC 2 inhibitors (2008) (0)
- Direct determination of the extent of racemization during post peptide synthesis reactions (1995) (0)
- Novel N-acetylated opioid peptides determined through the use of synthetic peptide combinatorial libraries (1993) (0)
- Induction of Anti-RF Antibodies with PGL 1 Peptide 325 (2003) (0)
- Figure 4, TRAIL Sensitization Studies of Cancer Cells Pre-Treated with Probe CID 44176340 (MLS-0412053) [ML183] (2011) (0)
- Synthesis of oligomeric multiple equimolar mixtures, especially mixtures oligopeptide. (1991) (0)
- Preclinical development of xiapuradamib therapy for lung cancer (2006) (0)
- Cytokine-retentive materials (1995) (0)
- XIAP-positive diffuse large B-cell lymphoma cells Small-molecule XIAP antagonist restores caspase-9-mediated apoptosis in (2012) (0)
- Cytokine-absorbing substances (1994) (0)
- The generation of peptide combinatorial libraries using tea-bag synthesisIdentification of B-cell epitopes (1996) (0)
- Preparation of heterocyclic positional scanning combinatorial libraries from peptides (1999) (0)
- Screening of peptidomimetic libraries for antitumor activity (2000) (0)
- Solid Phase Synthesis of 1,2,4-Triazinan-3-ones (2001) (0)
- The generation of peptide combinatorial libraries using tea-bag synthesis (1996) (0)
- Peptides that inhibit binding of von Willebrand factor. (1987) (0)
- TNFα-Based Peptides as Bioprobes for Exosites of ADAM Proteases (2013) (0)
- Table 1, PubChem Assay Summaries for Probe project (2010) (0)
- Utility of Soluble Peptide Combinatorial Libraries (1995) (0)
- Solid phase synthesis of heterocyclic combinatorial libraries derived from peptides (2002) (0)
- Method for producing proteins of Mycobacterium tuberculosis and antigenic peptides thereof. (1988) (0)
- Electromagnetic measurements, Operation Teapot. Final report (1957) (0)
- Chemical basis for variation in the major antigenic site elicting neutralizing antibodies in foot-and-mouth disease virus (1984) (0)
- (/sup 3/H)-beta-endorphin binding in rat brain (1984) (0)
- New Antiproliferative Agents from a Peptidomimetic Library (2001) (0)
- From Tens to Trillions - Advances in Synthetic Combinatorial Chemistry of Peptides, Peptidomimetics and Heterocyclic Compounds Derived from Peptides (2006) (0)
- Restricting agents cytokines. (1994) (0)
- Activation of human class-II restricted T cell clones by short peptides (1998) (0)
- Table 2, Reagents used for the uHTS experiments (2010) (0)
- Figure 2, Protein surfaces of BIR2 (A) and BIR3 (B) at the SMAC binding site; docked poses of CID25241665 (MLS-0391005) in BIR2 (C) and CID25241639 (MLS-0390982) in BIR3 (D) (2010) (0)
- Identification of Novel Ligands for Vasopressin V2 Receptor from Positional Scanning Libraries (2001) (0)
- Isolation of Populations of Antipeptide Antibodies Directed against Different Epitopes of the Same Fragment (1985) (0)
- Figure 2, Key SAR for our second library (2011) (0)
- Peptide used for purification of factor viii (1988) (0)
- Human T cell responses to myelin basic protein isoforms (1993) (0)
- Operation Sandstone. Nuclear explosions. 1948. Scientific Director's report of atomic weapon tests. Annex 7, Part 2. Technical photography measurements. Sandstone report No. 28 (1950) (0)
- Immunodominant ctl epitope of hiv 1 envelope protein the relationship between viral mutation and ctl specificity (1990) (0)
- Discovery of Selective Nanomolar Potent Melanocortin-3 Receptor Ligands (2018) (0)
- Mycobacterial recombinant and peptide (1988) (0)
- CB&DD Editorial Advisory Board (fourth in series) (2006) (0)
- Synthetic polypeptide for detecting mycobacterial infection (1994) (0)
- Synthesis of compounds (3,5,7) -1-H-imidazo (1,5-a) imidazole-2 (3H) -one. (2000) (0)
- Enzyme linked immunosorbent assay (ELISA) for beta-endorphin and its antibodies. (1983) (0)
- The central effect of MCH system studied using a specific MCH 1R antagonist isolated from combinatorial libraries (2006) (0)
- Table A1, Bir1/2 vs Bir3 potency and selectivity data for 153 additional compounds (2011) (0)
- Corrigendum to "A Study Of Human T-Cell Lines Generated From Multiple Sclerosis Patients And Controls By Stimulation With Peptides Of Myelin Basic Protein" (J. Neuroimmunol. 70, 65-74) (1997) (0)
- The design of self-assembling peptide complexes using conformationally defined libraries (1996) (0)
- Combinatorial Chemistry: Mixture-Based Combinatorial Libraries of Acyclic and Heterocyclic Compounds from Amino Acids and Short Peptides (2003) (0)
- Accuracy and Reliability of a Short-Baseline Narol System (1957) (0)
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