Richard C. Mulligan
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American molecular biologist
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Richard C. Mulliganbiology Degrees
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Molecular Biology
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Biology
Richard C. Mulligan's Degrees
- PhD Molecular Biology University of California, Berkeley
- Bachelors Biology University of California, Berkeley
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Why Is Richard C. Mulligan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Richard C. Mulligan is an American scientist who is the Mallinckrodt Professor of Genetics at Harvard Medical School, the Director of the Harvard Gene Therapy Initiative and a visiting scientist at the Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology. He is also the head of SanaX at Sana Biotechnology.
Richard C. Mulligan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo (1996) (2990)
- Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. (1993) (2825)
- Dystrophin expression in the mdx mouse restored by stem cell transplantation (1999) (1901)
- "Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells (2002) (1782)
- The basic science of gene therapy. (1993) (1671)
- Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus (1983) (1657)
- Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene (1991) (1327)
- PTH/PTHrP Receptor in Early Development and Indian Hedgehog--Regulated Bone Growth (1996) (1293)
- Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6 (2006) (1229)
- Engineering vascularized skeletal muscle tissue (2005) (1217)
- Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species (1997) (1150)
- Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene. (1994) (1117)
- Physiological consequences of loss of plasminogen activator gene function in mice (1994) (1107)
- A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. (1996) (971)
- Telomere dysfunction induces metabolic and mitochondrial compromise (2011) (960)
- Construction and applications of a highly transmissible murine retrovirus shuttle vector (1984) (851)
- Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. (1988) (850)
- Developmental potential and dynamic behavior of hematopoietic stem cells (1986) (826)
- Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase. (1981) (810)
- Expression of a bacterial gene in mammalian cells. (1980) (640)
- Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. (1998) (591)
- Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites (1998) (581)
- Induction of immunity to prostate cancer antigens: results of a clinical trial of vaccination with irradiated autologous prostate tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor using ex vivo gene transfer. (1999) (506)
- Isolation and Transplantation of Autologous Circulating Endothelial Cells Into Denuded Vessels and Prosthetic Grafts: Implications for Cell-Based Vascular Therapy (2003) (472)
- Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse (1984) (456)
- Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer. (1997) (453)
- Heterogeneity of the Angiogenic Response Induced in Different Normal Adult Tissues by Vascular Permeability Factor/Vascular Endothelial Growth Factor (2000) (428)
- Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis. (1993) (417)
- Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids (1981) (390)
- Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells. (1995) (359)
- High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range. (1984) (353)
- Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization. (1993) (351)
- N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility (2001) (343)
- Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways. (1996) (337)
- Implantation of vascular grafts lined with genetically modified endothelial cells. (1989) (326)
- Unexpectedly efficient homing capacity of purified murine hematopoietic stem cells. (2004) (315)
- TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells. (2004) (315)
- Lineage-specific expression of a human β-globin gene in murine bone marrow transplant recipients reconstituted with retrovirus-transduced stem cells (1988) (301)
- Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma. (2003) (298)
- Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer (2001) (295)
- Dose-dependent response of FGF-2 for lymphangiogenesis. (2004) (285)
- Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow. (2006) (284)
- Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene (1992) (284)
- Failure of bone marrow to reconstitute lung epithelium. (2005) (280)
- Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma. (2003) (280)
- Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice. (1996) (279)
- Synthesis of rabbit β-globin in cultured monkey kidney cells following infection with a SV40 β-globin recombinant genome (1979) (276)
- Expression of an exogenous growth hormone gene by transplantable human epidermal cells. (1987) (263)
- Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors (1981) (260)
- Exogenous control of mammalian gene expression through modulation of RNA self-cleavage (2004) (251)
- Generation and characterization of urokinase receptor-deficient mice. (1996) (236)
- Demonstration of a rational strategy for human prostate cancer gene therapy. (1994) (214)
- Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells (1986) (198)
- Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene. (1995) (194)
- Negative regulation of human c-fos expression by thes retinoblastoma gene product (1990) (193)
- Expression of human class II major histocompatibility complex antigens using retrovirus vectors. (1987) (190)
- Surfactant metabolism in transgenic mice after granulocyte macrophage-colony stimulating factor ablation. (1996) (189)
- Retrovirus-mediated transfer of human adenosine deaminase gene sequences into cells in culture and into murine hematopoietic cells in vivo. (1986) (181)
- Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens (1986) (179)
- Two dominant-acting selectable markers for gene transfer studies in mammalian cells. (1988) (171)
- Telomere dysfunction induces metabolic and mitochondrial compromise (2011) (168)
- A chicken-yeast chimeric β-tubulin protein is incorporated into mouse microtubules in vivo (1986) (164)
- VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis (2006) (162)
- Comparative Analysis of Genetically Modified Dendritic Cells and Tumor Cells as Therapeutic Cancer Vaccines (2000) (161)
- Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer (2006) (156)
- Gene transfer as cancer therapy. (1995) (150)
- Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination. (1993) (150)
- Protection of bone marrow transplant recipients from lethal doses of methotrexate by the generation of methotrexate-resistant bone marrow (1987) (146)
- Efficiency of transduction of highly purified murine hematopoietic stem cells by lentiviral and oncoretroviral vectors under conditions of minimal in vitro manipulation. (2005) (145)
- Hoechst dye efflux reveals a novel CD7(+)CD34(-) lymphoid progenitor in human umbilical cord blood. (2000) (144)
- Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector (1987) (143)
- Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit. (1988) (143)
- Bioactive murine and human interleukin-12 fusion proteins which retain antitumor activity in vivo (1997) (143)
- High efficiency gene transfer into primary human tumor explants without cell selection. (1993) (132)
- Noninvasive Bioluminescence Imaging of Luciferase Expressing Intracranial U87 Xenografts: Correlation with Magnetic Resonance Imaging Determined Tumor Volume and Longitudinal Use in Assessing Tumor Growth and Antiangiogenic Treatment Effect (2006) (131)
- Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice. (2003) (131)
- Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome. (2008) (130)
- Long-Lived Antitumor CD8+ Lymphocytes for Adoptive Therapy Generated Using an Artificial Antigen-Presenting Cell (2007) (129)
- Repression of the IgH enhancer in teratocarcinoma cells associated with a novel octamer factor. (1989) (126)
- Retrovirus-mediated transduction of adult hepatocytes. (1988) (126)
- Genetically modified keratinocytes transplanted to wounds reconstitute the epidermis. (1994) (126)
- Pre-proparathyroid hormone: a direct translation product of parathyroid messenger RNA. (1974) (124)
- Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes. (1990) (122)
- Factors governing the expression of a bacterial gene in mammalian cells. (1981) (121)
- Ovulation efficiency is reduced in mice that lack plasminogen activator gene function: functional redundancy among physiological plasminogen activators. (1995) (120)
- Ultrastructural Localization of the Vascular Permeability Factor/Vascular Endothelial Growth Factor (VPF/VEGF) Receptor-2 (FLK-1, KDR) in Normal Mouse Kidney and in the Hyperpermeable Vessels Induced by VPF/VEGF-expressing Tumors and Adenoviral Vectors (2000) (118)
- Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors (2002) (115)
- Oligomerization-Dependent Regulation of Motility and Morphogenesis by the Collagen Xviii Nc1/Endostatin Domain (2001) (113)
- XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice. (2006) (113)
- Negative regulation of human c-fos expression by the retinoblastoma gene product (1991) (110)
- Retroviral transfer of a murine cDNA for multidrug resistance confers pleiotropic drug resistance to cells without prior drug selection. (1988) (109)
- Soluble receptor-mediated selective inhibition of VEGFR and PDGFRβ signaling during physiologic and tumor angiogenesis (2008) (102)
- Tissue-specific and ectopic expression of genes introduced into transgenic mice by retroviruses. (1986) (102)
- Development of retrovirus vectors useful for expressing genes in cultured murine embryonal cells and hematopoietic cells in vivo (1988) (98)
- Expression of human adenosine deaminase in mice reconstituted with retrovirus-transduced hematopoietic stem cells. (1990) (97)
- Increased levels of spliced RNA account for augmented expression from the MFG retroviral vector in hematopoietic cells. (1996) (96)
- Insertion of the bacterial gpt gene into the germ line of mice by retroviral infection. (1985) (96)
- Involvement of interleukin-3 in delayed-type hypersensitivity. (1998) (94)
- Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan: clinical and immunological findings. (2004) (90)
- Retroviral expression of the human IL‐2 gene in a murine T cell line results in cell growth autonomy and tumorigenicity. (1987) (86)
- Characterization of ryudocan glycosaminoglycan acceptor sites. (1994) (85)
- Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages. (2010) (85)
- A phase I trial of adeno-associated virus serotype 1-γ-sarcoglycan gene therapy for limb girdle muscular dystrophy type 2C. (2012) (83)
- Gene therapy of metastatic cancer by in vivo retroviral gene targeting (1995) (82)
- Biological Effects of Disruption of the Tissue‐Type Plasminogen Activator, Urokinase‐Type Plasminogen Activator, and Plasminogen Activator Inhibitor‐1 Genes in Mice a (1994) (82)
- PPARα Deficiency in Inflammatory Cells Suppresses Tumor Growth (2007) (82)
- Peripheral blood progenitors as a target for genetic correction of p47phox-deficient chronic granulomatous disease. (1993) (80)
- Cancer cells engineered to secrete granulocyte-macrophage colony-stimulating factor using ex vivo gene transfer as vaccines for the treatment of genitourinary malignancies (2000) (79)
- Macrophage Growth Factors Introduced into the Kidney Initiate Renal Injury (1996) (77)
- One-day ex vivo culture allows effective gene transfer into human nonobese diabetic/severe combined immune-deficient repopulating cells using high-titer vesicular stomatitis virus G protein pseudotyped retrovirus. (1999) (75)
- A phase I study of vaccination with autologous, irradiated melanoma cells engineered to secrete human granulocyte-macrophage colony stimulating factor. (1997) (75)
- Pathway-specific regulation of the synthesis of anticoagulantly active heparan sulfate. (1994) (73)
- Efficient repopulation of denuded rabbit arteries with autologous genetically modified endothelial cells. (1994) (73)
- Autologous CLL cell vaccination early after transplant induces leukemia-specific T cells. (2013) (71)
- Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells (2007) (71)
- Nitric oxide is a regulator of hematopoietic stem cell activity. (2004) (68)
- Genetically engineered T cells to target EGFRvIII expressing glioblastoma (2009) (68)
- Critical Role for Hematopoietic Cell Kinase (Hck)-mediated Phosphorylation of Gab1 and Gab2 Docking Proteins in Interleukin 6-induced Proliferation and Survival of Multiple Myeloma Cells* (2004) (68)
- Expression of Bcl-XL Restores Cell Survival, but Not Proliferation and Effector Differentiation, in Cd28-Deficient T Lymphocytes (2000) (68)
- Cytokine production and function in c-mpl-deficient mice: no physiologic role for interleukin-3 in residual megakaryocyte and platelet production. (1998) (67)
- Secretion of human parathyroid hormone from rat pituitary cells infected with a recombinant retrovirus encoding preproparathyroid hormone. (1984) (67)
- Introduction of a selectable gene into different animal tissue by a retrovirus recombinant vector. (1984) (67)
- Activities of granulocyte-macrophage colony-stimulating factor revealed by gene transfer and gene knockout studies. (1994) (63)
- Versatile Retrovirus Vector Systems for Regulated Gene Expression In Vitro and In Vivo (1997) (61)
- Induction of Antigen-Specific Tumor Immunity by Genetic and Cellular Vaccines against MAGE: Enhanced Tumor Protection by Coexpression of Granulocyte-Macrophage Colony-Stimulating Factor and B7-1 (1996) (61)
- Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. (2006) (60)
- Individual adenovirus type 5 early region 1A gene products elicit distinct alterations of cellular morphology and gene expression (1985) (59)
- A novel stem-cell population in adult liver with potent hematopoietic-reconstitution activity. (2005) (58)
- Restoration of growth potential in paraclones of human keratinocytes by a viral oncogene. (1989) (57)
- Exogenous control of mammalian gene expression via modulation of translational termination (2006) (56)
- Subtyping Analysis of Fanconi Anemia by Immunoblotting and Retroviral Gene Transfer (1998) (53)
- Engineering high-speed allosteric hammerhead ribozymes (2007) (52)
- Lack of toxicity of alpha-sarcoglycan overexpression supports clinical gene transfer trial in LGMD2D (2008) (51)
- Simian virus 40 DNA directs synthesis of authentic viral polypeptides in a linked transcription-translation cell-free system. (1975) (48)
- Adenovirus-mediated delivery of a soluble form of the VEGF receptor Flk1 delays the growth of murine and human pancreatic adenocarcinoma in mice. (2002) (48)
- Prolonged xenograft survival of islets infected with small doses of adenovirus expressing CTLA4Ig. (1999) (48)
- Construction and properties of replication-competent murine retroviral vectors encoding methotrexate resistance (1989) (47)
- Response to Comments on " 'Stemness': Transcriptional Profiling of Embryonic and Adult Stem Cells" and "A Stem Cell Molecular Signature" (2003) (46)
- Efficient and stable expression of recombinant fibronectin polypeptides. (1987) (46)
- Genetic interventions for vein bypass graft disease: a review. (2002) (45)
- Gene Therapy of Prostate Cancer with the Soluble Vascular Endothelial Growth Factor Receptor Fk1 (2002) (44)
- Antisense RNA complementary to 3' coding and noncoding sequences of creatine kinase is a potent inhibitor of translation in vivo. (1989) (42)
- PPAR\(\alpha\) Deficiency in Inflammatory Cells Suppresses Tumor Growth (2007) (41)
- Erratum: Telomere dysfunction induces metabolic and mitochondrial compromise (Nature (2011) 470 (359-365)) (2011) (41)
- Structural Requirements of SLP-76 in Signaling via the High-Affinity Immunoglobulin E Receptor (FcεRI) in Mast Cells (2003) (39)
- Direct biochemical mapping of eukaryotic viral DNA by means of a linked transcription-translation cell-free system. (1976) (39)
- Induction of protective anti-tumor immunity by gene-modified dendritic cells. (1995) (38)
- Construction of Highly Transmissible Mammalian Cloning Vehicles Derived from Murine Retroviruses (1983) (36)
- A biochemical and ultrastructural evaluation of the type 2 Gaucher mouse. (1995) (35)
- Successful inhibition of intracranial human glioblastoma multiforme xenograft growth via systemic adenoviral delivery of soluble endostatin and soluble vascular endothelial growth factor receptor-2: laboratory investigation. (2008) (34)
- A TVA–Single-Chain Antibody Fusion Protein Mediates Specific Targeting of a Subgroup A Avian Leukosis Virus Vector to Cells Expressing a Tumor-Specific Form of Epidermal Growth Factor Receptor (2000) (32)
- Structure and expression of HLA-DQα and -DXα genes: interallelic alternate splicing of the HLA-DQα gene and functional splicing of the HLA-DXα gene using a retroviral vector (2004) (32)
- Tissue-specific expression of functionally rearranged lambda 1 Ig gene through a retrovirus vector. (1987) (30)
- Gene therapy to target dendritic cells from blood to lymph nodes (2003) (30)
- Adoptive immunotherapy of cancer with activated lymph node cells primed in vivo with autologous tumor cells transduced with the GM-CSF gene. (1996) (29)
- Lineage specific expression of a human beta-globin gene in murine bone marrow transplant recipients. (1988) (29)
- Retrovirus-mediated transfer of the human glucocerebrosidase gene to Gaucher fibroblasts. (1986) (29)
- Tumor metastasis biopsy as a surrogate marker of response to melanoma immunotherapy. (1999) (28)
- Expression of HLA-DR antigen in human class II mutant B-cell lines by double infection with retrovirus vectors (1987) (28)
- In vivo and in vitro Modulation of Immune Stimulatory Capacity of Primary Dendritic Cells by Adenovirus-Mediated Gene Transduction (1998) (27)
- Synthesis of rabbit beta-globin in cultured monkey kidney cells following infection with a SV40 beta-globin recombinant genome. (1979) (27)
- Transplantation of islets transduced with CTLA4-Ig and TGFbeta using adenovirus and lentivirus vectors. (2004) (26)
- Glucose-induced Toxicity in Insulin-producing Pituitary Cells That Coexpress GLUT2 and Glucokinase (2001) (26)
- The molecular biology of Gaucher disease and the potential for gene therapy. (1986) (24)
- Progress reports on immune gene therapy for stage IV renal cell cancer using lethally irradiated granulocyte-macrophage colony-stimulating factor-transduced autologous renal cancer cells (2000) (22)
- Side Population Hematopoietic Stem Cells Promote Wound Healing in Diabetic Mice (2007) (21)
- Targeting Avian Leukosis Virus Subgroup A Vectors by Using a TVA-VEGF Bridge Protein (2001) (21)
- Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli. (2007) (21)
- Cell encapsulation technology as a novel strategy for human anti-tumor immunotherapy (2011) (21)
- Direct delivery of leptin to the hypothalamus using recombinant adeno-associated virus vectors results in increased therapeutic efficacy (2001) (20)
- Purification and characterization of retrovirally transduced hematopoietic stem cells. (1992) (19)
- Rescue of type I collagen-deficient phenotype by retroviral-vector-mediated transfer of human pro alpha 1(I) collagen gene into Mov-13 cells (1987) (18)
- Recombinant adeno-associated virus type 2 pseudotypes: comparing safety, specificity, and transduction efficiency in the primate striatum. Laboratory investigation. (2011) (17)
- A case report: Immune responses and clinical course of the first human use of granulocyte/macrophage-colony-stimulating-factor-transduced autologous melanoma cells for immunotherapy (1997) (17)
- Long-term in vivo expression of the MFG-ADA retroviral vector in rhesus monkeys transplanted with transduced bone marrow cells. (1997) (16)
- Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells. (2003) (15)
- Eukaryotic chromosome transfer: linkage of the murine major histocompatibility complex to an inserted dominant selectable marker. (1984) (15)
- Detecting T-cell reactivity to whole cell vaccines (2012) (15)
- Metaphase chromosome transfer of introduced selectable markers. (1984) (14)
- Retroviral-mediated transfer and expression of human beta-globin genes in cultured murine and human erythroid cells. (1988) (14)
- Transfer of a mutant dihydrofolate reductase gene into pre- and postimplantation mouse embryos by a replication-competent retrovirus vector (1989) (13)
- Advanced renal cell carcinoma treated with granulocyte‐macrophage colony‐stimulating factor gene therapy: A clinical course of the first Japanese experience (2002) (13)
- Use of CD9 expression to enrich for porcine hematopoietic progenitors. (2002) (13)
- Transgenic animals as tools for the study of fibrinolysis in vivo (1994) (12)
- Transduction of LacZ gene into leukemia cells using viral vectors of retrovirus and adenovirus. (1995) (11)
- High efficiency gene transfer into murine T cell clones using a retroviral vector. (1986) (11)
- Repopulation of injured arteries with genetically modified endothelial cells. (1992) (10)
- High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range. 1984. (1992) (10)
- Evidence that the level of the p55 component of the interleukin (IL) 2 receptor can control IL 2 responsiveness in a murine IL 3‐dependent cell (1990) (9)
- A phase I study of vaccination with lethally irradiated, autologous nonsmall cell lung carcinoma cells engineered by adenoviral mediated gene transfer to secrete human granulocyte-macrophage colony stimulating factor (2000) (9)
- 1. Generation by Homologous Recombination and Characterization (1993) (9)
- A gene transfer system establishes interleukin-6 neither promotes nor suppresses renal injury. (1996) (8)
- Inactivation of the mouse urokinase-receptor gene (1994) (7)
- Gene therapy for pancreatic cancer. (2002) (7)
- Isolation and Functional Properties of Murine Hematopoietic Stem Cells that are Replicating In Vivo By Margaret A. Goodell, Katja Brose, Glenn Paradis,* (1996) (7)
- Somatic gene transfer in the development of an animal model for primary hyperparathyroidism. (1992) (7)
- Production of spliced DNA copies of the cottontail rabbit papillomavirus genome in a retroviral vector. (1986) (7)
- Gaucher disease: A tale of two species (1995) (6)
- FORMATION OF β-GLOBIN FOLLOWING INFECTION WITH RECOMBINANTS CONTAINING RABBIT β-GLOBIN cDNA AT DIFFERENT LOCATIONS OF SV40's LATE REGION (1980) (6)
- H-2Ld antigen encoded by a recombinant retrovirus genome is expressed on the surface of infected cells (1985) (6)
- Genetically modified endothelial cells in the treatment of human diseases. (1989) (6)
- Use of retroviral vectors for mapping of splice sites in cottontail rabbit papillomavirus. (1988) (5)
- Corrigendum: VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis (2009) (5)
- Gene transfer and gene therapy (1988) (5)
- Regulation of the fibrinolytic system during gonadotropin-induced ovulation in mice with inactivation of the genes encoding tPA, uPA or PAI-i (1994) (4)
- Development of gene transfer technology. (2014) (3)
- II. Effects on Hemostasis, Thrombosis, and Thrombolysis (1993) (3)
- A mammalian cell-based assay for screening inhibitors of RNA cleavage. (2009) (3)
- Development ofRetrovirus Vectors Useful forExpressing Genesin Cultured MurineEmbryonal Cells andHematopoietic Cells InVivo (1988) (3)
- Critical role for Hck-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin-6-induced proliferation and survival of multiple myeloma cells. (2003) (2)
- Gene transfer of macrophage growth factors into the kidney of lpr mice initiates renal injury. (1996) (2)
- hematopoietic-reconstitution activity A novel stem-cell population in adult liver with potent (2005) (1)
- Generation of a high-titer retroviral vector capable of expressing high levels of the human ( 8-globin gene ( hemoglobinopathies / gene therapy / locus control region ) (2005) (1)
- Critical role for Hck-mediated phosphorylation of Gab1 and Gab2 docking proteins in IL-6- induced proliferation and survival of MM cells (2004) (1)
- Hypoxia-Independent Regulation of Hepatic Erythropoietin Production by Vascular Endothelial Growth Factor. (2004) (1)
- Dispensable sequence motifs in the RAGI and RAG-2 genes for plasmid V ( D ) J recombination ( recombination activating genes / cysteine-rich motifs / topoisomerase homology ) (2005) (1)
- Amelioration Of Emphysema In Mice Via Lentiviral Transduction Of Long-lived Pulmonary Alveolar Macrophages (2010) (0)
- Lentivirus-Based Expression of Human Alpha-1 Antitrypsin Ameliorates Emphysema in Mice. (2009) (0)
- MODULATION OF IMMUNE RESPONSES INDUCED BY GENE TRANSDUCED DENDRITIC CELLS (1998) (0)
- RescueofTypeICollagen-Deficient Phenotype byRetroviral- Vector-Mediated Transfer ofHumanprocl(I) Collagen Geneinto Mov-13Cells (1987) (0)
- Off the Shelf, GMP Grade Artificial APC Efficiently Generates Large Numbers of Antigen Specific CTLs Sufficient for the Treatment of Cancer and Infectious Disease. (2004) (0)
- Cellules epitheliales exprimant un materiau genetique etranger (1986) (0)
- Arteries With Autologous Genetically Modified Endothelial Cells (2005) (0)
- Gene transfer using genetically altered cells transplanted on biodegradable polymer scaffolds into newborn fischer rats (1992) (0)
- Functional Studies of Human Bone Marrow Derived Side Population Cells. (2004) (0)
- Specific Killing of EGFRvIII Expressing Tumor Cells by Genetically Engineered Cytotoxic T Lymphocytes (1998) (0)
- InVivoGeneDelivery andStable Transduction of Nondividing Cells bya Lentiviral Vector (2016) (0)
- Antiangiogenic gene therapy delays growth of murine and human pancreatic adenocarcinoma in mice (2001) (0)
- Analysis of the metabolic requirements for the creation of immunoresistant β cell surrogates (2000) (0)
- Efficient andstable expression ofrecombinant fibronectin polypeptides (1987) (0)
- COMPARISON OF LOCAL VS. SYSTEMIC CTLA4Ig IN THE PROLONGATION OF ISLET XENOGRAFT SURVIVAL (1998) (0)
- Factors governing the expression of a bacterial gene in mammalian cells (1981) (0)
- Keratinocytes Express an Intracellular Marker Gene and Regenerate the Epidermis in Porcine Full-Thickness Wounds After Retroviral Gene Transfer (1995) (0)
- Adoptive immunotherapy of human melanoma in a HU/SCID model: 479 (1997) (0)
- Useful retroviral vectors for gene therapy (1991) (0)
- 617 Preclinical animal model of immunogene therapy for lung cancer (1997) (0)
- Binding protein VEGF for blocking angiogenesis (2012) (0)
- Radiation therapy plus ADFlk1-Fc has a synergistic effect against fibrosarcoma T241 in mice (2001) (0)
- Data ‘ Stemness ’ : Transcriptional Profiling of Embryonic and Adult Stem Cells (0)
- RABBIT β GLOBIN SYNTHESIS IN CULTURED MONKEY KIDNEY CELLS INFECTED WITH SV40 β GLOBIN RECOMBINANT GENOMES (1979) (0)
- A Novel Secreted Form of the Angiogenesis Inhibitor Endostatin Prolongs Survival in Mice Inoculated with U-87 Tumor Xenografts (1998) (0)
- Human β-Globin Expression in Murine Bone Marrow Transplant Recipients Reconstituted with Retrovirally Transduced Stem Cells (1989) (0)
- 998 Immunotherapy with autologous, irradiated melanoma cells transduced with the GM-CSF gene (1995) (0)
- Intradermal vaccination with GM-CSF-transduced autologous melanoma induces dendritic cell migration: 476 (1997) (0)
- Reparation genique a induction de clivage d'adn bicatenaire en un site cible chromosomique (2000) (0)
- Immune response to vaccination with autologous melanoma transduced to secrete GM-CSF: 107 (1997) (0)
- Vegf bining protein to block angiogeneses (2012) (0)
- Unexpected Functions of Granulocyte-Macrophage Colony Stimulating Factor (1996) (0)
- Genetic alteration of endothelial cells (1991) (0)
- Chimeric T-cell Receptor Therapy for Glioblastoma Multiforme: 895 (2006) (0)
- Gene Therapy Gene Therapy for Wiskott Aldrich Syndrome-Rescue of T-Cell Signaling and Amelioration of Colitis upon Transplantation of Retrovirally Transduced Hematopoietic Stem Cells in Mice (2002) (0)
- Bioactive fusion proteins of IL-12. (1996) (0)
- Transduktionsveränderte fibroblasts and their application. (1988) (0)
- Procedes et compositions de regulation de l'expression genique (2006) (0)
- Long-term expression of human parathyroid hormone in rats after gene transfer into syngeneic fibroblasts: A model for osteoclast-mediated bone resorption (1990) (0)
- Rapid Publication Generation and Characterization of Urokinase Receptor-deficient Mice (1996) (0)
- Gene transfer and gene therapy : proceedings of an E.I. du Pont de Nemours-UCLA Symposium, held at Tamarron, Colorado, February 6-12, 1988 (1989) (0)
- Gene therapy for malignant melanoma: clinical aspects (1997) (0)
- 4980286 In vivo introduction and expression of foreign genetic material in epithelial cells (1986) (0)
- Retroviral expression ofthehumanIL-2geneina murineT cell line results incell growth autonomyandtumorigenicity (1987) (0)
- Preparative and Clinical Studies of Immunogene Therapy Using Autologous GM-CSF Transduced Tumor Vaccines for Stage IV Renal Cell Cancer (1999) (0)
- SUSTAINED INHIBITION OF BRAIN TUMOR GROWTH BY RECOMBINANT ADENO-ASSOCIATED VIRUS ENCODING ENDOST ATIN (2017) (0)
- Modified hepatocytes and their application (1989) (0)
- Common Marmoset as a New Preclinical Animal Model for Human Gene Therapy of Hematological Disorders (1996) (0)
- Utilisation of albumin to enhance in vivo delivery of sirna across the vascular endothelium (2011) (0)
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