Richard D Kolodner

Richard D Kolodner's AcademicInfluence.com Rankings

Richard D Kolodner

Biology

#5358

World Rank

#7816

Historical Rank

Cell Biology

#146

World Rank

#153

Historical Rank

Molecular Biology

#471

World Rank

#481

Historical Rank

Biochemistry

#619

World Rank

#713

Historical Rank

biology Degrees

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Biology

Richard D Kolodner's Degrees

PhD Biochemistry University of California, Berkeley
Bachelors Chemistry University of California, Berkeley

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Richard D Kolodner's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer (1993) (2439)
Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer (1994) (2147)
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. (1998) (2005)
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. (1997) (1549)
α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models (2006) (1278)
Eukaryotic DNA mismatch repair. (1999) (896)
Saccharomyces Ku70, Mre11/Rad50, and RPA Proteins Regulate Adaptation to G2/M Arrest after DNA Damage (1998) (780)
Biochemistry and genetics of eukaryotic mismatch repair. (1996) (636)
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. (1996) (590)
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. (1996) (588)
Meiotic Pachytene Arrest in MLH1-Deficient Mice (1996) (578)
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. (1993) (537)
The evolution of genes: the chicken preproinsulin gene (1980) (527)
Maintenance of Genome Stability in Saccharomyces cerevisiae (2002) (501)
Rewiring of Genetic Networks in Response to DNA Damage (2010) (458)
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. (2000) (444)
A Novel Mutation Avoidance Mechanism Dependent on S. cerevisiae RAD27 Is Distinct from DNA Mismatch Repair (1997) (437)
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. (1997) (398)
Mammalian MutS homologue 5 is required for chromosome pairing in meiosis (1999) (391)
The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model. (2007) (378)
Mutation in the Mismatch Repair Gene Msh6 Causes Cancer Susceptibility (1997) (378)
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants (1999) (377)
The structure and evolution of the two nonallelic rat preproinsulin genes (1979) (371)
Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae (2001) (359)
Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions. (1992) (357)
Germ-line msh6 mutations in colorectal cancer families. (1999) (349)
An overview of Cdk1-controlled targets and processes (2010) (342)
Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines. (1995) (339)
Identification of mismatch repair genes and their role in the development of cancer. (1995) (325)
Suppression of Spontaneous Chromosomal Rearrangements by S Phase Checkpoint Functions in Saccharomyces cerevisiae (2001) (323)
Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility. (2003) (323)
SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination (2001) (315)
Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families (1996) (313)
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. (1994) (312)
Mismatch repair: mechanisms and relationship to cancer susceptibility. (1995) (306)
The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. (1998) (299)
Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations. (1994) (289)
Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coli. (1989) (270)
Protein interactions in genetic recombination in Escherichia coli. Interactions involving RecO and RecR overcome the inhibition of RecA by single-stranded DNA-binding protein. (1994) (263)
A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations (2003) (258)
Biochemical interaction of the Escherichia coli RecF, RecO, and RecR proteins with RecA protein and single-stranded DNA binding protein. (1993) (253)
The molecular size and conformation of the chloroplast DNA from higher plants. (1975) (248)
A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor. (2002) (247)
Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex (2000) (242)
Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. (1994) (241)
Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression (2002) (239)
MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae. (1999) (228)
Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics. (2007) (224)
Genetic recombination of bacterial plasmid DNA: effect of RecF pathway mutations on plasmid recombination in Escherichia coli (1985) (223)
Structure of the human MLH1 locus and analysis of a large hereditary nonpolyposis colorectal carcinoma kindred for mlh1 mutations. (1995) (223)
Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations inMSH2 and MLH1 (2000) (223)
Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins. (1992) (219)
Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro (1997) (204)
Inverted repeats in chloroplast DNA from higher plants. (1979) (203)
Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. (1998) (203)
Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. (1997) (200)
Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families. (2002) (200)
exo1-Dependent Mutator Mutations: Model System for Studying Functional Interactions in Mismatch Repair (2001) (196)
Visualization of Eukaryotic DNA Mismatch Repair Reveals Distinct Recognition and Repair Intermediates (2011) (191)
An essential Saccharomyces cerevisiae single‐stranded DNA binding protein is homologous to the large subunit of human RP‐A. (1990) (184)
Identification of EpCAM as the gene for congenital tufting enteropathy. (2008) (183)
Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas. (1995) (179)
Characterization of DNA-binding and strand-exchange stimulation properties of y-RPA, a yeast single-strand-DNA-binding protein. (1992) (172)
Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin (2003) (170)
Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination. (1998) (168)
The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. (2000) (166)
Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae (2002) (164)
Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility. (2004) (162)
Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair. (1998) (160)
The genetic dependence of recombination in recD mutants of Escherichia coli. (1988) (153)
The Evolutionarily Conserved Zinc Finger Motif in the Largest Subunit of Human Replication Protein A Is Required for DNA Replication and Mismatch Repair but Not for Nucleotide Excision Repair* (1998) (151)
Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches. (1994) (149)
Functional analysis of human MLH1 variants using yeast and in vitro mismatch repair assays. (2007) (146)
Interpretation of genetic test results for hereditary nonpolyposis colorectal cancer: implications for clinical predisposition testing. (1999) (145)
Saccharomyces cerevisiae chromatin-assembly factors that act during DNA replication function in the maintenance of genome stability (2003) (141)
Zea mays chloroplast ribosomal RNA genes are part of a 22,000 base pair inverted repeat (1977) (140)
recA-independent general genetic recombination of plasmids (1981) (136)
Mutation screening in the hMLH1 gene in Swedish hereditary nonpolyposis colon cancer families. (1995) (134)
The Structure of Chloroplast DNA (1979) (134)
Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16. (1996) (132)
Analysis of the Interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 Complexes with DNA Using a Reversible DNA End-blocking System* (2005) (132)
Specific pathways prevent duplication-mediated genome rearrangements (2009) (131)
Physicochemical characterization of mitochondrial DNA from pea leaves. (1972) (131)
Biochemical Characterization of the Interaction between theSaccharomyces cerevisiae MSH2-MSH6 Complex and Mispaired Bases in DNA* (1999) (131)
Physical interaction between components of DNA mismatch repair and nucleotide excision repair. (1998) (130)
The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA. (2007) (128)
Identification of a locus on chromosome 1q44 for familial cold urticaria. (2000) (127)
Characterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication. (1991) (124)
Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice (2005) (123)
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae. (2007) (122)
Transfer of the MSH2·MSH6 Complex from Proliferating Cell Nuclear Antigen to Mispaired Bases in DNA* (2003) (122)
The mismatch repair complex hMutS alpha recognizes 5-fluorouracil-modified DNA: implications for chemosensitivity and resistance. (2004) (122)
A biological network in Saccharomyces cerevisiae prevents the deleterious effects of endogenous oxidative DNA damage. (2005) (121)
Effect of 8-oxoguanine on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II. (2004) (120)
Links between replication, recombination and genome instability in eukaryotes. (2000) (118)
Saccharomyces cerevisiae Mer3 Helicase Stimulates 3′–5′ Heteroduplex Extension by Rad51 Implications for Crossover Control in Meiotic Recombination (2004) (117)
Chloroplast DNA from higher plants replicates by both the Cairns and the rolling circle mechanism (1975) (117)
Mismatch Repair, But Not Heteroduplex Rejection, Is Temporally Coupled to DNA Replication (2011) (115)
The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions. (1995) (115)
Genetic recombination of bacterial plasmid DNA. Analysis of the effect of recombination-deficient mutations on plasmid recombination. (1982) (114)
Homologous pairing and strand exchange promoted by the Escherichia coli RecT protein. (1994) (111)
An FHA domain–mediated protein interaction network of Rad53 reveals its role in polarized cell growth (2006) (104)
Exonuclease 1-dependent and independent mismatch repair. (2015) (104)
Saccharomyces cerevisiae Msh2-Msh3 Acts in Repair of Base-Base Mispairs (2007) (102)
Strand exchange protein 1 from Saccharomyces cerevisiae. A novel multifunctional protein that contains DNA strand exchange and exonuclease activities. (1991) (102)
Saccharomyces cerevisiae pol30(Proliferating Cell Nuclear Antigen) Mutations Impair Replication Fidelity and Mismatch Repair (1999) (100)
Characterization of hereditary nonpolyposis colorectal cancer families from a population-based series of cases. (2001) (100)
Chromosome healing by de novo telomere addition in Saccharomyces cerevisiae (2006) (100)
The Recombination-deficient Mutant RPA (rfa1-t11) Is Displaced Slowly from Single-stranded DNA by Rad51 Protein* (2003) (99)
Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA. (1997) (99)
Checkpoint proteins control morphogenetic events during DNA replication stress in Saccharomyces cerevisiae (2006) (97)
Genetic and physical analysis of plasmid recombination in recB recC sbcB and recB recC sbcA Escherichia coli K-12 mutants. (1989) (97)
Mononucleotide microsatellite instability and germlineMSH6 mutation analysis in early onset colorectal cancer (1999) (97)
Perspectives on the DNA damage and replication checkpoint responses in Saccharomyces cerevisiae. (2009) (96)
Inhibition of Msh6 ATPase activity by mispaired DNA induces a Msh2(ATP)-Msh6(ATP) state capable of hydrolysis-independent movement along DNA. (2006) (96)
Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants. (2000) (96)
Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae (1998) (94)
Dynamic Changes in Protein-Protein Interaction and Protein Phosphorylation Probed with Amine-reactive Isotope Tag*S (2005) (94)
Targeting of nonexpressed genes in embryonic stem cells via homologous recombination. (1989) (94)
Molecular size and conformation of chloroplast deoxyribonucleic acid from pea leaves. (1972) (92)
DNA Strand Invasion Promoted by Escherichia coli RecT Protein* (1998) (91)
Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. (2019) (89)
Purification and characterization of the Escherichia coli RecO protein. Renaturation of complementary single-stranded DNA molecules catalyzed by the RecO protein. (1994) (88)
Genetic recombination of bacterial plasmid DNA. Physical and genetic analysis of the products of plasmid recombination in Escherichia coli. (1983) (88)
New insights into the mechanism of DNA mismatch repair (2015) (88)
Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control (1995) (87)
Specificity of mismatch repair following transformation of Saccharomyces cerevisiae with heteroduplex plasmid DNA. (1989) (87)
Requirement of Rrm3 Helicase for Repair of Spontaneous DNA Lesions in Cells Lacking Srs2 or Sgs1 Helicase (2004) (87)
Induction of genome instability by DNA damage in Saccharomyces cerevisiae. (2003) (86)
Regulation and intracellular localization of Saccharomyces cerevisiae strand exchange protein 1 (Sep1/Xrn1/Kem1), a multifunctional exonuclease (1995) (86)
Molecular and genetic analysis of the gene encoding the Saccharomyces cerevisiae strand exchange protein Sep1 (1991) (85)
Partial purification of an enzyme from Saccharomyces cerevisiae that cleaves Holliday junctions. (1985) (85)
Purification and characterization of an activity from Saccharomyces cerevisiae that catalyzes homologous pairing and strand exchange. (1987) (85)
The role of heteroduplex correction in gene conversion in Saccharomyces cerevisiae (1987) (84)
Oxygen metabolism and reactive oxygen species cause chromosomal rearrangements and cell death (2007) (84)
PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair. (2014) (82)
A conserved MutS homolog connector domain interface interacts with MutL homologs (2009) (81)
Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P (2003) (80)
The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase (2007) (77)
Novel dominant mutations in Saccharomyces cerevisiae MSH6 (2000) (75)
Exonuclease VIII of Escherichia coli. II. Mechanism of action. (1983) (74)
Purification and preliminary characterization of the Escherichia coli K-12 recF protein (1990) (74)
Replication protein A is required for meiotic recombination in Saccharomyces cerevisiae. (2002) (74)
The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. (2001) (74)
‘Saccharomyces cerevisiae MSH2/6 Complex Interacts with Holliday Junctions and Facilitates Their Cleavage by Phage Resolution Enzymes* (1999) (73)
Saccharomyces cerevisiae RRM3, a 5′ to 3′ DNA Helicase, Physically Interacts with Proliferating Cell Nuclear Antigen* (2002) (72)
Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements (2013) (71)
EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer. (2003) (70)
Molecular analysis of the Escherichia coli recO gene (1989) (67)
Cloning and characterization of the human and Caenorhabditis elegans homologs of the Saccharomyces cerevisiae MSH5 gene. (1998) (67)
The effect of DNA mismatches on the ATPase activity of MSH1, a protein in yeast mitochondria that recognizes DNA mismatches. (1994) (67)
Intramolecular recombination of linear DNA catalyzed by the Escherichia coli RecE recombination system. (1985) (67)
Isolation and Characterization of New Proliferating Cell Nuclear Antigen (POL30) Mutator Mutants That Are Defective in DNA Mismatch Repair (2002) (67)
Peroxiredoxin Tsa1 Is the Key Peroxidase Suppressing Genome Instability and Protecting against Cell Death in Saccharomyces cerevisiae (2009) (65)
Control of Translocations between Highly Diverged Genes by Sgs1, the Saccharomyces cerevisiae Homolog of the Bloom'sSyndrome Protein (2006) (65)
Escherichia coli MutS Tetramerization Domain Structure Reveals That Stable Dimers but Not Tetramers Are Essential for DNA Mismatch Repair in Vivo* (2007) (64)
Regulation of the Human MSH6 Gene by the Sp1 Transcription Factor and Alteration of Promoter Activity and Expression by Polymorphisms (2003) (64)
Dominant Saccharomyces cerevisiae msh6 Mutations Cause Increased Mispair Binding and Decreased Dissociation from Mispairs by Msh2-Msh6 in the Presence of ATP* (2002) (63)
Saccharomyces cerevisiae Mer3 Is a DNA Helicase Involved in Meiotic Crossing Over (2002) (63)
Replication of duplex DNA by bacteriophage T7 DNA polymerase and gene 4 protein is accompanied by hydrolysis of nucleoside 5'-triphosphates. (1977) (63)
Multiple functions of MutS- and MutL-related heterocomplexes. (1999) (62)
A Genetic and Structural Study of Genome Rearrangements Mediated by High Copy Repeat Ty1 Elements (2011) (62)
Recombination and the Tel1 and Mec1 checkpoints differentially effect genome rearrangements driven by telomere dysfunction in yeast (2004) (62)
Tumour predisposition and cancer syndromes as models to study gene–environment interactions (2020) (61)
Checkpoint kinases regulate a global network of transcription factors in response to DNA damage. (2013) (61)
Gene conversion in Escherichia coli. Resolution of heteroallelic mismatched nucleotides by co-repair. (1986) (60)
Cloning and direct examination of a structurally abnormal human beta 0-thalassemia globin gene. (1980) (59)
Saccharomyces cerevisiae as a Model System To Define the Chromosomal Instability Phenotype (2005) (58)
Mismatch repair and cancer susceptibility. (1994) (58)
Chromosome healing through terminal deletions generated by de novo telomere additions in Saccharomyces cerevisiae. (2004) (57)
Analysis of gross-chromosomal rearrangements in Saccharomyces cerevisiae. (2006) (57)
A human compound heterozygote for two MLH1 missense mutations (1997) (56)
Reconstitution of long and short patch mismatch repair reactions using Saccharomyces cerevisiae proteins (2013) (56)
The MER3 Helicase Involved in Meiotic Crossing Over Is Stimulated by Single-stranded DNA-binding Proteins and Unwinds DNA in the 3′ to 5′ Direction* (2001) (55)
Interaction between the Msh2 and Msh6 Nucleotide-binding Sites in the Saccharomyces cerevisiae Msh2-Msh6 Complex* (2010) (55)
Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae. (1998) (55)
Repair of heteroduplex plasmid DNA after transformation into Saccharomyces cerevisiae (1986) (55)
Sensitivity and speciﬁcity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1 (2000) (54)
Identification and Characterization of the Escherichia coli RecT Protein, a Protein Encoded by the recE Region That Promotes Renaturation of Homologous Single-Stranded DNA (1993) (52)
Suppression of spontaneous genome rearrangements in yeast DNA helicase mutants (2006) (51)
Mitotic checkpoint function in the formation of gross chromosomal rearrangements in Saccharomyces cerevisiae. (2004) (51)
Exonuclease VIII of Escherichia coli. I. Purification and physical properties. (1983) (51)
The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination. (1995) (50)
Genetic recombination of homologous plasmids catalyzed by cell-free extracts of saccharomyces cerevisiae (1983) (50)
DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals (2013) (49)
Aneuploidy Drives a Mutator Phenotype in Cancer (2011) (49)
Dominant Mutations in S. cerevisiae PMS1 Identify the Mlh1-Pms1 Endonuclease Active Site and an Exonuclease 1-Independent Mismatch Repair Pathway (2013) (48)
Electron microscopic visualization of RecT protein and its complexes with DNA. (1995) (48)
Nucleotide sequence of the Escherichia coli recJ chromosomal region and construction of recJ-overexpression plasmids (1991) (48)
Post-Replication Repair Suppresses Duplication-Mediated Genome Instability (2010) (47)
Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases. (2009) (47)
A Saccharomyces cerevisiae RNase H2 Interaction Network Functions To Suppress Genome Instability (2014) (47)
Identification and characterization of the Escherichia coli RecT protein, a protein encoded by the recE region that promotes renaturation of homologous single-stranded DNA (1993) (47)
Functional analysis of human mismatch repair gene mutations identifies weak alleles and polymorphisms capable of polygenic interactions (2010) (46)
Coupling distant sites in DNA during DNA mismatch repair (2007) (45)
Mispair-specific Recruitment of the Mlh1-Pms1 Complex Identifies Repair Substrates of the Saccharomyces cerevisiae Msh2-Msh3 Complex* (2014) (45)
Mismatch correction catalyzed by cell-free extracts of Saccharomyces cerevisiae. (1986) (45)
Identification and characterization of Saccharomyces cerevisiae EXO 1 , a gene encoding an exonuclease that interacts with MSH 2 (1997) (44)
Chimeric Saccharomyces cerevisiae Msh6 protein with an Msh3 mispair-binding domain combines properties of both proteins (2007) (43)
Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae (2009) (42)
Presence of displacement loops in the covalently closed circular chloroplast deoxyribonucleic acid from higher plants. (1975) (42)
Mutational analysis of the hMSH2 gene reveals a three base pair deletion in a family predisposed to colorectal cancer development. (1994) (42)
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways (2019) (41)
Determination of gross chromosomal rearrangement rates. (2010) (41)
Initial description of the human NLRP3 promoter (2008) (40)
Pathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiae (2017) (40)
Replication of bacteriophage T7 DNA by purified proteins. (1979) (39)
A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair. (2016) (39)
Probing DNA- and ATP-mediated Conformational Changes in the MutS Family of Mispair Recognition Proteins Using Deuterium Exchange Mass Spectrometry* (2010) (39)
A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers (2016) (38)
Physical studies on the size and structure of the covalently closed circular chloroplast DNA from higher plants. (1976) (38)
FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination (2020) (38)
The MER3 DNA Helicase Catalyzes the Unwinding of Holliday Junctions* (2002) (37)
Alternative splicing regulates stochastic NLRP3 activity (2019) (37)
A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6–Bre1 to cell cycle progression (2011) (37)
Hallmarks of homology recognition by RecA‐like recombinases are exhibited by the unrelated Escherichia coli RecT protein (2003) (36)
Functional Studies and Homology Modeling of Msh2-Msh3 Predict that Mispair Recognition Involves DNA Bending and Strand Separation (2010) (36)
Suppression of gross chromosomal rearrangements by the multiple functions of the Mre11-Rad50-Xrs2 complex in Saccharomyces cerevisiae. (2005) (35)
Purification and characterization of a protein from Saccharomyces cerevisiae that binds tightly to single-stranded DNA and stimulates a cognate strand exchange protein. (1989) (35)
Denaturation mapping studies on the circular chloroplast deoxyribonucleic acid from pea leaves. (1975) (35)
Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners (2018) (34)
Effect of DNA structure and nucleotide sequence on Holliday junction resolution by a Saccharomyces cerevisiae endonuclease. (1988) (34)
Genetic recombination of bacterial plasmid DNA: electron microscopic analysis of in vitro intramolecular recombination. (1980) (34)
Stabilization of Dicentric Translocations through Secondary Rearrangements Mediated by Multiple Mechanisms in S. cerevisiae (2009) (33)
Mlh2 Is an Accessory Factor for DNA Mismatch Repair in Saccharomyces cerevisiae (2014) (33)
Biochemical basis for dominant mutations in the Saccaromyces cerevisiae Msh6 gene (2006) (32)
The molecular size of the herpes simplex virus type 1 genome. (1974) (32)
Renaturation of DNA by a Saccharomyces cerevisiae protein that catalyzes homologous pairing and strand exchange. (1988) (30)
Checkpoint functions are required for normal S-phase progression in Saccharomyces cerevisiae RCAF- and CAF-I-defective mutants. (2006) (29)
Mapping of Escherichia coli chromosomal Tn5 and F insertions by pulsed field gel electrophoresis. (1988) (29)
Gene 4 protein of bacteriophage T7. Purification physical properties, and stimulation of T7 DNA polymerase during the elongation of polynucleotide chains. (1978) (28)
Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System* (2015) (27)
Low frequency of hMSH2 mutations in Swedish HNPCC families (1997) (27)
Genetic analysis of ionizing radiation-induced mutagenesis in Saccharomyces cerevisiae reveals TransLesion Synthesis (TLS) independent of PCNA K164 SUMOylation and ubiquitination. (2006) (25)
Isolation of genetic elements that increase frequencies of plasmid recombinants (1983) (25)
Effect of terminal non-homology on intramolecular recombination of linear plasmid substrates in Escherichia coli. (1992) (25)
Gene conversion in Escherichia coli: the recF pathway for resolution of heteroduplex DNA (1989) (25)
Germline characterization of early-aged onset of hereditary non-polyposis colorectal cancer. (2001) (24)
Escherichia coli strains containing mutations in the structural gene for topoisomerase I are recombination deficient (1984) (24)
Human peroxiredoxin PrxI is an orthologue of yeast Tsa1, capable of suppressing genome instability in Saccharomyces cerevisiae. (2008) (24)
The Saccharomyces cerevisiae Rad6 Postreplication Repair and Siz1/Srs2 Homologous Recombination-Inhibiting Pathways Process DNA Damage That Arises in asf1 Mutants (2009) (23)
Analysis of the recE locus of Escherichia coli K-12 by use of polyclonal antibodies to exonuclease VIII (1988) (23)
Bioinformatic identification of genes suppressing genome instability (2012) (23)
Reconstitution of Saccharomyces cerevisiae DNA polymerase ε-dependent mismatch repair with purified proteins (2017) (22)
Gene 4 protein of bacteriophage T7. Characterization of the product synthesized by the T7 DNA polymerase and gene 4 protein in the absence of ribonucleoside 5'-triphosphates. (1978) (21)
Human mismatch repair genes and their association with hereditary non-polyposis colon cancer. (1994) (21)
The properties of Msh2–Msh6 ATP binding mutants suggest a signal amplification mechanism in DNA mismatch repair (2018) (20)
The presence of covalently linked ribonucleotides in the closed circular deoxyribonucleic acid from higher plants. (1975) (20)
Recruiting research participants at community education sites. (2005) (20)
Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q (2008) (20)
Origin, transmission, and segregation of mitochondrial DNA dimers in mouse hybrid and cybrid cell lines (1984) (19)
An Escherichia coli cell-free system that catalyzes the repair of symmetrically methylated heteroduplex DNA. (1984) (19)
Accurate, high-throughput "snapshot" detection of hMLH1 mutations by two-dimensional DNA electrophoresis. (1998) (18)
DNA Repair Pathway Selection Caused by Defects in TEL1, SAE2, and De Novo Telomere Addition Generates Specific Chromosomal Rearrangement Signatures (2014) (18)
Structure of the Human MLH 1 Locus and Analysis of a Large Hereditary Nonpolyposis Colorectal Carcinoma Kindred for mihi Mutations ' (2006) (18)
Clinical presentation correlates with the type of mismatch repair gene involved in hereditary nonpolyposis colon cancer. (2003) (17)
Interaction of a Saccharomyces cerevisiae strand exchange stimulatory factor with DNA. (1990) (16)
Intron splice acceptor site sequence variation in the hereditary non-polyposis colorectal cancer gene hMSH2. (1994) (16)
Construction of a synthetic Holliday junction analog and characterization of its interaction with a Saccharomyces cerevisiae endonuclease that cleaves Holliday junctions. (1987) (16)
Cdc73 suppresses genome instability by mediating telomere homeostasis (2018) (15)
Loss of the Thioredoxin Reductase Trr1 Suppresses the Genomic Instability of Peroxiredoxin tsa1 Mutants (2014) (15)
The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects (2018) (15)
Germ-line msh 6 Mutations in Colorectal Cancer Families 1 (1999) (14)
The activity of the Saccharomyces cerevisiae strand exchange protein 1 intrinsic exonuclease during joint molecule formation. (1994) (14)
Stimulation of precise excision and recombination by conjugal proficient F′ plasmids (1986) (14)
Genetic recombination catalyzed by cell-free extracts of Saccharomyces cerevisiae. (1984) (14)
EXO 1 Variants Occur Commonly in Normal Population : Evidence against a Role in Hereditary Nonpolyposis Colorectal Cancer 1 (2002) (14)
Structure of Chloroplast DNA (1977) (14)
Rapid Analysis of Saccharomyces cerevisiae Genome Rearrangements by Multiplex Ligation–Dependent Probe Amplification (2012) (14)
Engineered Disulfide-forming Amino Acid Substitutions Interfere with a Conformational Change in the Mismatch Recognition Complex Msh2-Msh6 Required for Mismatch Repair* (2012) (14)
DNA repair: Guarding against mutation (2000) (13)
Ligation of newly replicated DNA controls the timing of DNA mismatch repair (2021) (13)
Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability (2016) (12)
Saccharomyces cerevisiae pms2 mutations are alleles of MLH1, and pms2-2 corresponds to a hereditary nonpolyposis colorectal carcinoma-causing missense mutation (1996) (11)
SUMO E3 ligase Mms21 prevents spontaneous DNA damage induced genome rearrangements (2017) (11)
S-Score: A Scoring System for the Identification and Prioritization of Predicted Cancer Genes (2014) (10)
Plasmid recombination intermediates generated in a Saccharomyces cerevisiae cell-free recombination system (1985) (9)
Plasmids of Shigella dysenteriae Y6R: a Defective Col Factor (1973) (9)
Analyzing Genome Rearrangements in Saccharomyces cerevisiae. (2018) (9)
Regulation of the reverse transcriptase of human immunodeficiency virus type 1 by dNTPs. (1992) (9)
Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. (2019) (8)
Rad27 and Exo1 function in different excision pathways for mismatch repair in Saccharomyces cerevisiae (2021) (8)
Advances in Brief A Hereditary Nonpolyposis Colorectal Carcinoma Case Associated with Hypermethylation of the MLH 1 Gene in Normal Tissue and Loss of Heterozygosity of the Unmethylated Allele in the Resulting Microsatellite Instability-High Tumor 1 (2002) (8)
Mechanisms underlying genome instability mediated by formation of foldback inversions in Saccharomyces cerevisiae (2020) (7)
Purification of a strand exchange stimulatory factor from Saccharomyces cerevisiae. (1990) (7)
The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc 9 DNA ligase (2007) (7)
Cis lethal genetic interactions attenuate and alter p53 tumorigenesis (2010) (7)
Erratum: Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair (Cancer Cell (2019) 35(3) (504–518.e7), (S1535610819300546), (10.1016/j.ccell.2019.01.020)) (2019) (7)
Essential Saccharomyces cerevisiae genome instability suppressing genes identify potential human tumor suppressors (2019) (7)
Molecular Biology of Neoplastic Transformation of the Large Bowel: Identification of Two Etiologic Pathways (1994) (7)
Enzymology of homologous recombination in Saccharomyces cerevisiae. (1993) (6)
Instability-High Tumor Unmethylated Allele in the Resulting Microsatellite Normal Tissue and Loss of Heterozygosity of the Gene in MLH 1 Associated with Hypermethylation of the A Hereditary Nonpolyposis Colorectal Carcinoma Case (2002) (6)
Title The recombination-deficient mutant RPA ( rfa 1t 11 ) is displaced slowly from single-stranded DNA by Rad 51 protein (2003) (6)
Characterization of the interaction of Saccharomyces cerevisiae strand exchange protein 1 with DNA. (1994) (5)
An FHA domain‐mediated protein interaction network links rad53 to cytokinesis (2006) (5)
What makes the engine hum (2012) (4)
Advances in Brief The DNA Mismatch Repair Genes Msh 3 and Msh 6 Cooperate in Intestinal Tumor Suppression 1 (2000) (4)
The yeast HSM3 gene is not involved in DNA mismatch repair in rapidly dividing cells. (2000) (4)
Molecular and Genetic Analysis of the Gene Encoding the Saccharomyces cerevisiae Strand Exchange Protein Sepl (2003) (4)
Erratum: Characterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication (Journal of Biological Chemistry (1991) 266 (12090-12098)) (1993) (4)
DNA Mismatch Repair: Mechanisms and Cancer Genetics (2014) (3)
Genes essential for cell viability that are linked to tumor suppressor genes play a role in cancer susceptibility (2010) (3)
Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. (2019) (2)
THE STRUCTURE AND TRANSCRIPTION OF RAT PREPROINSULIN GENES (1979) (2)
Saccharomyces cerevisiae proteins involved in hybrid DNA formation in vitro. (1991) (2)
GENETIC RECOMBINATION OF BACTERIAL PLASMID DNAS IN VIVO AND IN VITRO (1980) (2)
Molecular Size and the Information Content of Chloroplast DNAs from Higher Plants (1975) (2)
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2 (canceryhereditary nonpolyposis colorectal carcinomaymutagenesisymutS) (1997) (2)
Genes for plastid ribosomal proteins and RNAs. (1977) (2)
A common MSH 2 mutation in English and North American HNPCC families : origin , phenotypic expression , and sex specific di V erences in colorectal cancer (1999) (2)
The unstructured linker of Mlh1 contains a motif required for endonuclease function which is mutated in cancers (2022) (1)
Physical and genetic properties of chloroplast DNA. (1980) (1)
Genome Sizes of Chloroplast and Mitochondrial DNA's in Higher Plants (1972) (1)
Cooper in Parkinson ' s Models-Synuclein Blocks ER-Golgi Traffic and Rab 1 Rescues Neuron Loss (2013) (1)
Mlh1 interacts with both Msh2 and Msh6 for recruitment during mismatch repair (2022) (1)
Analysis of the Interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 Complexes with DNA Using a Reversible DNA End-blocking System*□S (2005) (0)
The s q l Mutant of Saccharomyces cereukiae Arrests in Pachytene and Is Deficient in Meiotic Recombination (2002) (0)
Keystone Symposia on Molecular and Cellular Biology: 'The molecular basis of cancer'. Organizers: Carol L. Prives and George F. Vande Woude, Taos, NM, 15-21 March 1999. (2000) (0)
DNA Mismatch Repair Defects and Cancer (2004) (0)
P III B.10 Identification and characterization of exo/endonucleases involved in mutation avoidance in S. cerevisiae (1997) (0)
Template homology determines the genetics and mechanisms of gross chromosomal rearrangements in S. cerevisiae (736.11) (2014) (0)
Compositions and methods for ralaterer DNA mismatch repair genes (1994) (0)
recF-dependent induction ofrecAsynthesis bycoumermycin, a specific inhibitor oftheBsubunit ofDNAgyrase (1983) (0)
Gene Analysis of the Progression of Cancer (2001) (0)
Ligation and supercoiling of plasmids containing single strand interruptions (2021) (0)
Saccharomyces cerevisiaeprotein-encoding clones for Approaching a complete repository of sequence-verified data (2007) (0)
MutS C-terminal domain fused to Maltose Binding Protein (2007) (0)
Genome Rearrangement and Stability. (1995) (0)
Abstract KP01: Identification of genes and pathways that prevent genome instability (2015) (0)
GeneConversion inEscherichia coli: theRecFPathway for Resolution ofHeteroduplex DNA (1989) (0)
Analysis of yeast SUMO ligase MMS21‐dependent genome maintenance pathway (925.4) (2014) (0)
Required for Mismatch Repair Recognition Complex Msh 2-Msh 6 Conformational Change in the Mismatch Substitutions Interfere with a Engineered Disulfide-forming Amino Acid DNA and Chromosomes : (2012) (0)
Rad5 and Its Human Homologs, HLTF and SHPRH, Are Novel Interactors of Mismatch Repair (2022) (0)
Mismatch Repair: Biochemistry and Genetics (2002) (0)
Plasmid at 10 years (1987) (0)
Germline characterization of early-aged onset of HNPCC (2000) (0)
New insights into the mechanism of DNA mismatch repair (2015) (0)
Multiple functions of Mu MutL-related heterocomf (2016) (0)
1 PROBING DNA AND ATP-MEDIATED CONFORMATIONAL CHANGES IN THE MUTS FAMILY OF MISPAIR RECOGNITION PROTEINS USING DEUTERIUM EXCHANGE MASS SPECTROMETRY (2010) (0)
Supporting Online Material for Rewiring of Genetic Networks in Response to DNA Damage (2010) (0)
2-Msh 3 Complex Saccharomyces cerevisiae Substrates of the Mlh 1-Pms 1 Complex Identifies Repair Mispair-specific Recruitment of the DNA and Chromosomes : (2014) (0)
of the reductase Trr1 suppresses the genomic instability of peroxiredoxin tsa1 mutants. (2014) (0)
Identification of different classes of genome instability suppressor genes through analysis of DNA damage response markers (2022) (0)
Suppression of genome insta S-phase checkpoint pathwayv Saccharomyces cerevisiae (2016) (0)
Mismatch Repair and Recombination EXO 1 , an Exonuclease Implicated in Saccharomyces cerevisiae Identification of a Human Gene Encoding a Homologue of Updated (2006) (0)
Nucleases. Stuart M. Linn , Richard J. Roberts (1983) (0)
The complex prevents genome instability induced by replication fork progression defects. (2018) (0)
Correction: Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements (2016) (0)
mlh 1 Mutations Hereditary Nonpolyposis Colorectal Carcinoma Kindred for Locus and Analysis of a Large MLH 1 Structure of the Human Updated (2006) (0)
Tumour predisposition and cancer syndromes as models to study gene–environment interactions (2020) (0)
The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects (2018) (0)
Saccharomyces cerevisiae Proteins That Promote Hybrid DNA Formation in Vitro (1992) (0)
Procede de detection des alterations du processus de reparation des mauvais appariements de l'adn (1994) (0)
Author response: Mechanisms underlying genome instability mediated by formation of foldback inversions in Saccharomyces cerevisiae (2020) (0)
Author Correction: Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners (2019) (0)
Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners (2018) (0)

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