Richard E. Carson
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Engineering Computer Science
Richard E. Carson's Degrees
- PhD Computer Science Stanford University
- Bachelors Computer Engineering California Institute of Technology
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Why Is Richard E. Carson Influential?
(Suggest an Edit or Addition)According to Wikipedia, Richard Ellis Carson is an American researcher and biomedical engineer. He is currently Professor of Radiology and Biomedical Imaging and of Biomedical Engineering at Yale University. At Yale he is also Director of the PET Center and Director of Graduate Studies in Biomedical Engineering. His research focuses on the application of mathematical techniques to the study of humans and primates with Positron Emission Tomography.
Richard E. Carson's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- EM reconstruction algorithms for emission and transmission tomography. (1984) (1935)
- Consensus Nomenclature for in vivo Imaging of Reversibly Binding Radioligands (2007) (1854)
- Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method. (1997) (1174)
- Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study. (1997) (1142)
- Dissociation of object and spatial visual processing pathways in human extrastriate cortex. (1991) (976)
- Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis (2016) (716)
- Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia (2002) (645)
- Regional cerebral blood flow throughout the sleep- wake cycle (1997) (626)
- Linearized Reference Tissue Parametric Imaging Methods: Application to [11C]DASB Positron Emission Tomography Studies of the Serotonin Transporter in Human Brain (2003) (594)
- Physiological activation of a cortical network during performance of the Wisconsin Card Sorting Test: A positron emission tomography study (1995) (545)
- Dissociated pattern of activity in visual cortices and their projections during human rapid eye movement sleep. (1998) (463)
- Identification and Differentiation of Resting Myocardial Ischemia and Infarction in Man with Positron Computed Tomography, 18F‐labeled Fluorodeoxyglucose and N‐13 Ammonia (1983) (447)
- Noise Reduction in the Simplified Reference Tissue Model for Neuroreceptor Functional Imaging (2002) (379)
- Comparison of Bolus and Infusion Methods for Receptor Quantitation: Application to [18F]Cyclofoxy and Positron Emission Tomography (1993) (364)
- Reduced Serotonin Type 1A Receptor Binding in Panic Disorder (2004) (356)
- Tomographic mapping of human cerebral metabolism (1982) (348)
- Altered patterns of cerebral activity during speech and language production in developmental stuttering. An H2(15)O positron emission tomography study. (1997) (346)
- Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease (2004) (338)
- Strategies to Improve Neuroreceptor Parameter Estimation by Linear Regression Analysis (2002) (306)
- Deficits in prefrontal cortical and extrastriatal dopamine release in schizophrenia: a positron emission tomographic functional magnetic resonance imaging study. (2015) (304)
- Imaging synaptic density in the living human brain (2016) (302)
- Species-specific calls evoke asymmetric activity in the monkey's temporal poles (2004) (293)
- Elevated Brain Cannabinoid CB1 Receptor Availability in Posttraumatic Stress Disorder: A Positron Emission Tomography Study (2013) (280)
- Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC. (2006) (264)
- Design of a motion-compensation OSEM list-mode algorithm for resolution-recovery reconstruction for the HRRT (2003) (261)
- Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging (2018) (259)
- Imaging robust microglial activation after lipopolysaccharide administration in humans with PET (2015) (251)
- Quantification of Amphetamine-Induced Changes in [11C]Raclopride Binding with Continuous Infusion (1997) (242)
- Lower synaptic density is associated with depression severity and network alterations (2019) (218)
- Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma (2013) (208)
- Clinically Relevant Doses of Methylphenidate Significantly Occupy Norepinephrine Transporters in Humans In Vivo (2010) (207)
- Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology (2016) (201)
- Four distinct trajectories of tau deposition identified in Alzheimer’s disease (2021) (200)
- Quantitative Measurement of Local Cerebral Blood Flow in Humans by Positron Computed Tomography and 15O-Water (1983) (197)
- Kinetic Modeling of [11C]Raclopride: Combined PET-Microdialysis Studies (1997) (196)
- The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: A [11C]PBR28 PET study (2013) (186)
- Endotoxin-induced systemic inflammation activates microglia: [11C]PBR28 positron emission tomography in nonhuman primates (2012) (179)
- Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain (2016) (177)
- A Noninvasive Positron Computed Tomography Technique Using Oxygen-15-Labeled Water for the Evaluation of Neurobehavioral Task Batteries (1985) (172)
- The Functional Neuroanatomy of Tourette's Syndrome: An FDG-PET Study. I. Regional Changes in Cerebral Glucose Metabolism Differentiating Patients and Controls (1993) (171)
- Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE (2015) (161)
- Imaging Neuroinflammation in Alzheimer's Disease with Radiolabeled Arachidonic Acid and PET (2008) (160)
- Widespread abnormality of the γ-aminobutyric acid-ergic system in Tourette syndrome. (2012) (154)
- Measurement of Local Blood Flow and Distribution Volume with Short-Lived Isotopes: A General Input Technique (1982) (144)
- Tomographic mapping of human cerebral metabolism: Sensory deprivation (1982) (143)
- Predicting Alzheimer’s disease progression using multi-modal deep learning approach (2019) (136)
- Toward an evolutionary perspective on conceptual representation: species-specific calls activate visual and affective processing systems in the macaque. (2004) (135)
- Quantitative functional brain imaging with positron emission tomography (1998) (131)
- Weighted Integration Method for Local Cerebral Blood Flow Measurements with Positron Emission Tomography (1986) (126)
- Rapid Changes in Cannabinoid 1 Receptor Availability in Cannabis-Dependent Male Subjects After Abstinence From Cannabis. (2016) (124)
- 5-HT 1A receptors are reduced in temporal lobe epilepsy after partial-volume correction. (2005) (121)
- A BOUNDARY METHOD FOR ATTENUATION CORRECTION IN POSITRON COMPUTED TOMOGRAPHY (1981) (121)
- Kinetic evaluation and test–retest reproducibility of [11C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans (2017) (119)
- A method for postinjection PET transmission measurements with a rotating source. (1988) (118)
- Brivaracetam, a selective high‐affinity synaptic vesicle protein 2A (SV2A) ligand with preclinical evidence of high brain permeability and fast onset of action (2016) (117)
- In Vivo Imaging of Endogenous Pancreatic β-Cell Mass in Healthy and Type 1 Diabetic Subjects Using 18F-Fluoropropyl-Dihydrotetrabenazine and PET (2012) (115)
- Dissociation of Object and Spatial Vision in Human Extrastriate Cortex: Age-Related Changes in Activation of Regional Cerebral Blood Flow Measured with [15 O]Water and Positron Emission Tomography (1992) (114)
- A Maximum Likelihood Method for Region-of-Interest Evaluation in Emission Tomography (1986) (114)
- Development of fluorine-18-labeled 5-HT1A antagonists. (1999) (114)
- Association of posttraumatic stress disorder with reduced in vivo norepinephrine transporter availability in the locus coeruleus. (2013) (113)
- In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET (2020) (113)
- Measurement of dopamine release with continuous infusion of [11C]raclopride: optimization and signal-to-noise considerations. (2000) (112)
- Quantification and pharmacokinetics of blood-brain barrier disruption in humans. (1996) (109)
- Evaluation of 3D reconstruction algorithms for a small animal PET camera (1996) (108)
- Hexanucleotide repeat expansions in C9ORF72 in the spectrum of motor neuron diseases (2012) (104)
- Alternative Statistical Models for the Examination of Clinical Positron Emission Tomography/Fluorodeoxyglucose Data (1985) (104)
- Opioid receptor imaging with positron emission tomography and [(18)F]cyclofoxy in long-term, methadone-treated former heroin addicts. (2000) (104)
- An approximation formula for the variance of PET region-of-interest values (1993) (104)
- Reduced muscarinic type 2 receptor binding in subjects with bipolar disorder. (2006) (101)
- Examination of Blood — Brain Barrier Permeability in Dementia of the Alzheimer Type with [68Ga]EDTA and Positron Emission Tomography (1987) (101)
- PET imaging of the effects of age and cocaine on the norepinephrine transporter in the human brain using (S,S)‐[11C]O‐methylreboxetine and HRRT (2010) (99)
- Brain incorporation of 11C-arachidonic acid, blood volume, and blood flow in healthy aging: a study with partial-volume correction. (2004) (97)
- Increased Nanoparticle Delivery to Brain Tumors by Autocatalytic Priming for Improved Treatment and Imaging. (2016) (96)
- Glucose Metabolism in the Insula and Cingulate Is Affected by Systemic Inflammation in Humans (2012) (96)
- Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease (2020) (96)
- Noise reduction in oncology FDG PET images by iterative reconstruction: a quantitative assessment. (2001) (95)
- Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence (2017) (94)
- Muscarinic Cholinergic Receptor Measurements with [18F]FP-TZTP: Control and Competition Studies (1998) (93)
- The Functional Neuroanatomy of Tourette's Syndrome: An FDG-PET Study. II: Relationships between Regional Cerebral Metabolism and Associated Behavioral and Cognitive Features of the Illness (1995) (93)
- Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [11C]-(+)-PHNO (2016) (92)
- Tracer Kinetic Modeling in PET (2005) (92)
- An analysis of signal amplification using small detectors in positron emission tomography. (1982) (91)
- Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [11C]ABP688 and PET imaging study in depression (2017) (90)
- Activation of cerebral blood flow during a visuoperceptual task in patients with Alzheimer-type dementia (1993) (90)
- Recovery from chronic spinal cord contusion after nogo receptor intervention (2011) (90)
- Altered cerebral gamma-aminobutyric acid type A-benzodiazepine receptor binding in panic disorder determined by [11C]flumazenil positron emission tomography. (2008) (90)
- Lateralization and gender differences in the dopaminergic response to unpredictable reward in the human ventral striatum (2011) (89)
- Affinity and selectivity of [11C]‐(+)‐PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo (2012) (86)
- Functional neuroanatomy of Tourette syndrome. Limbic-motor interactions studied with FDG PET. (1992) (86)
- 11C-PBR28 imaging in multiple sclerosis patients and healthy controls: test-retest reproducibility and focal visualization of active white matter areas (2015) (86)
- Synaptic Changes in Parkinson Disease Assessed with in vivo Imaging (2020) (85)
- Kinetic Analysis of the 5-HT2A Ligand [11C]MDL 100,907 (2000) (85)
- Reduced Brain Cannabinoid Receptor Availability in Schizophrenia (2016) (83)
- Noise characteristics of 3-D and 2-D PET images (1998) (83)
- PET physiological measurements using constant infusion. (2000) (83)
- Biodistribution and Radiation Dosimetry of LMI1195: First-in-Human Study of a Novel 18F-Labeled Tracer for Imaging Myocardial Innervation (2014) (82)
- Evaluation of motion correction methods in human brain PET imaging--a simulation study based on human motion data. (2013) (82)
- Clinical doses of atomoxetine significantly occupy both norepinephrine and serotonin transports: Implications on treatment of depression and ADHD (2014) (81)
- Reduced Amygdala Serotonin Transporter Binding in Posttraumatic Stress Disorder (2011) (81)
- Biodistribution, radiation dose estimates, and in vivo Pgp modulation studies of 18F-paclitaxel in nonhuman primates. (2003) (80)
- Assessment of Dynamic Neurotransmitter Changes with Bolus or Infusion Delivery of Neuroreceptor Ligands (1998) (79)
- Glucose utilization in a patient with hepatoma and hypoglycemia. Assessment by a positron emission tomography. (1992) (77)
- Reproducibility of Resting Cerebral Blood Flow Measurements with H215O Positron Emission Tomography in Humans (1993) (77)
- Synthesis and Evaluation of 11C-LY2795050 as a κ-Opioid Receptor Antagonist Radiotracer for PET Imaging (2013) (77)
- The effect of early trauma exposure on serotonin type 1B receptor expression revealed by reduced selective radioligand binding. (2011) (75)
- Kinetic Modeling of the Serotonin 5-HT1B Receptor Radioligand [11C]P943 in Humans (2010) (75)
- In Vivo Ketamine-Induced Changes in [11C]ABP688 Binding to Metabotropic Glutamate Receptor Subtype 5 (2015) (74)
- Cerebral Glucose Metabolism as a Function of Age in Man: Influence of the Rate Constants in the Fluorodeoxyglucose Method (1983) (74)
- Non-coding variability at the APOE locus contributes to the Alzheimer’s risk (2019) (74)
- Precision and accuracy of regional radioactivity quantitation using the maximum likelihood EM reconstruction algorithm (1994) (73)
- Quantitative measurement of myocardial blood flow with oxygen-15 water and positron computed tomography: an assessment of potential and problems. (1985) (73)
- No change in serotonin type 1A receptor binding in patients with posttraumatic stress disorder. (2005) (73)
- Decreased GABA-A binding on FMZ-PET in succinic semialdehyde dehydrogenase deficiency (2009) (72)
- Brain Incorporation of [11C]Arachidonic Acid in Young Healthy Humans Measured with Positron Emission Tomography (2002) (71)
- The Suitability of [11C]-α-Methyl-L-tryptophan as a Tracer for Serotonin Synthesis: Studies With Dual Administration of [11C] and [14C] Labeled Tracer (2000) (70)
- PET evaluation of [(18)F]FCWAY, an analog of the 5-HT(1A) receptor antagonist, WAY-100635. (2000) (70)
- Multimodality Bayesian algorithm for image reconstruction in positron emission tomography: a tissue composition model (1997) (70)
- Robust Identification of Alzheimer’s Disease subtypes based on cortical atrophy patterns (2017) (69)
- Nicotine-Induced Dopamine Release in Primates Measured with [11C]Raclopride PET (2004) (68)
- Serotonin 1B Receptor Imaging in Alcohol Dependence (2009) (68)
- Rapid Changes in CB1 Receptor Availability in Cannabis Dependent Males after Abstinence from Cannabis. (2016) (67)
- PET imaging of opiate receptor binding in human epilepsy using [18F]cyclofoxy (1992) (67)
- Effects of Early-Life Stress on Serotonin1A Receptors in Juvenile Rhesus Monkeys Measured by Positron Emission Tomography (2010) (66)
- Association of in vivo κ-opioid receptor availability and the transdiagnostic dimensional expression of trauma-related psychopathology. (2014) (66)
- Tomographic mapping of human cerebral metabolism (1984) (66)
- Post-injection transmission attenuation measurements for PET (1988) (65)
- Three-dimensional registration of cardiac positron emission tomography attenuation scans. (1993) (63)
- Mapping neurotransmitter systems to the structural and functional organization of the human neocortex (2021) (63)
- Imaging Glutamate Homeostasis in Cocaine Addiction with the Metabotropic Glutamate Receptor 5 Positron Emission Tomography Radiotracer [11C]ABP688 and Magnetic Resonance Spectroscopy (2014) (63)
- The watershed algorithm: a method to segment noisy PET transmission images (1998) (63)
- Intravascular streaming during carotid artery infusions. Demonstration in humans and reduction using diastole-phased pulsatile administration. (1991) (63)
- Parametric images of blood flow in oncology PET studies using [15O]water. (2000) (61)
- In vivo muscarinic 2 receptor imaging in cognitively normal young and older volunteers (2003) (61)
- Performance characteristics of the 3-D OSEM algorithm in the reconstruction of small animal PET images (2000) (61)
- Imaging the Cannabinoid CB1 Receptor in Humans with [11C] OMAR: Assessment of Kinetic Analysis Methods, Test–Retest Reproducibility, and Gender Differences (2015) (61)
- Kinetic Analysis of the Metabotropic Glutamate Subtype 5 Tracer [18F]FPEB in Bolus and Bolus-Plus-Constant-Infusion Studies in Humans (2013) (61)
- Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans (2012) (59)
- Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer’s disease (2017) (58)
- Assessment of a white matter reference region for 11C-UCB-J PET quantification (2020) (58)
- Benzodiazepine receptors mediate regional blood flow changes in the living human brain. (1995) (58)
- Arterial transit time effects in pulsed arterial spin labeling CBF mapping: Insight from a PET and MR study in normal human subjects (2010) (58)
- List-Mode PET Motion Correction Using Markerless Head Tracking: Proof-of-Concept With Scans of Human Subject (2013) (56)
- Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology (2020) (56)
- Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human (2014) (55)
- Relation of measured brain glucose utilisation and cerebral atrophy in man. (1987) (55)
- Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates. (2018) (55)
- Distribution and Kinetics of 3-O-Methyl-6-[18F]fluoro-L-DOPA in the Rhesus Monkey Brain (1991) (55)
- Pancreatic Beta Cell Mass PET Imaging and Quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in Rodent Models of Diabetes (2011) (55)
- Task-Related Interaction between Basal Ganglia and Cortical Dopamine Release (2007) (55)
- Higher in vivo muscarinic‐2 receptor distribution volumes in aging subjects with an apolipoprotein E‐ϵ4 allele (2003) (54)
- The Effect of Antiepileptic Drugs on 5‐HT1A–Receptor Binding Measured by Positron Emission Tomography (2006) (53)
- An investigation of a double-tracer technique for positron computerized tomography. (1982) (53)
- Metabotropic Glutamate Receptor 5 and Glutamate Involvement in Major Depressive Disorder: A Multimodal Imaging Study. (2017) (53)
- Positron emission tomography shows elevated cannabinoid CB1 receptor binding in men with alcohol dependence. (2012) (52)
- Unified Deadtime Correction Model For PET (1990) (52)
- The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory (2019) (52)
- Dopamine D₃ receptor alterations in cocaine-dependent humans imaged with [¹¹C](+)PHNO. (2014) (51)
- Cerebral blood flow with [15O]water PET studies using an image-derived input function and MR-defined carotid centerlines (2013) (51)
- In Vivo Synaptic Density Imaging with 11C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease (2019) (50)
- Evaluation of the agonist PET radioligand [11C]GR103545 to image kappa opioid receptor in humans: Kinetic model selection, test–retest reproducibility and receptor occupancy by the antagonist PF-04455242 (2014) (50)
- Brain Uptake of the Acid Metabolites of F-18—Labeled WAY 100635 Analogs (2003) (49)
- Regional Brain Measurement of Bmax and KD with the Opiate Antagonist Cyclofoxy: Equilibrium Studies in the Conscious Rat (1991) (49)
- Respiratory Motion Compensation for PET/CT with Motion Information Derived from Matched Attenuation-Corrected Gated PET Data (2018) (48)
- Variance reduction on randoms from coincidence histograms for the HRRT (2005) (47)
- Cannabinoid Type 1 Receptor Availability in the Amygdala Mediates Threat Processing in Trauma Survivors (2014) (47)
- Reductions in Brain 5-HT1B Receptor Availability in Primarily Cocaine-Dependent Humans (2014) (47)
- Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study (2019) (46)
- BLD: A Software System for Physiological Data Handling and Model Analysis (1981) (45)
- Measurement of Regional Rates of Cerebral Protein Synthesis with L-[1-11C]leucine and PET with Correction for Recycling of Tissue Amino Acids: II. Validation in Rhesus Monkeys (2005) (45)
- Radiosynthesis and in vivo evaluation of [(11)C]MP-10 as a positron emission tomography radioligand for phosphodiesterase 10A. (2011) (45)
- Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts (2016) (44)
- Precision and Accuracy Considerations of Physiological Quantitation in PET (1991) (44)
- List-mode reconstruction for the Biograph mCT with physics modeling and event-by-event motion correction (2013) (43)
- Opiate receptor avidity and cerebral blood flow in Alzheimer's disease (1997) (43)
- In vivo variation in same-day estimates of metabotropic glutamate receptor subtype 5 binding using [11C]ABP688 and [18F]FPEB (2017) (43)
- In Vivo Reactive Oxygen Species Detection With a Novel Positron Emission Tomography Tracer, 18F-DHMT, Allows for Early Detection of Anthracycline-Induced Cardiotoxicity in Rodents (2018) (43)
- Direct 4-D PET List Mode Parametric Reconstruction With a Novel EM Algorithm (2012) (42)
- Variance Reduction on Randoms from delayed coincidence histograms for the HRRT (2005) (42)
- Test–Retest Reproducibility of Binding Parameters in Humans with 11C-LY2795050, an Antagonist PET Radiotracer for the κ Opioid Receptor (2015) (41)
- PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies (2020) (41)
- Imaging Nicotine- and Amphetamine-Induced Dopamine Release in Rhesus Monkeys with [11C]PHNO vs [11C]raclopride PET (2014) (41)
- Brain Serotonin Synthesis Rates in Rhesus Monkeys Determined by [11C;[alpha;-Methyl-L-Tryptophan and Positron Emission Tomography Compared to CSF 5-Hydroxyindole-3-Acetic Acid Concentrations (1998) (41)
- Radiolabeling of Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles with Biotinylated F-18 Prosthetic Groups and Imaging of Their Delivery to the Brain with Positron Emission Tomography (2014) (41)
- PET Imaging for Early Detection of Alzheimer's Disease: From Pathologic to Physiologic Biomarkers. (2017) (40)
- Receptor Occupancy of the κ-Opioid Antagonist LY2456302 Measured with Positron Emission Tomography and the Novel Radiotracer 11C-LY2795050 (2016) (40)
- A single‐center, open‐label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers (2019) (40)
- PET imaging of α7 nicotinic acetylcholine receptors: a comparative study of [18F]ASEM and [18F]DBT-10 in nonhuman primates, and further evaluation of [18F]ASEM in humans (2017) (40)
- Kinetic Modeling of 11C-LY2795050, A Novel Antagonist Radiotracer for PET Imaging of the Kappa Opioid Receptor in Humans (2014) (40)
- Reduced synaptic vesicle protein 2A binding in temporal lobe epilepsy: A [11C]UCB‐J positron emission tomography study (2020) (40)
- Anti-edema and antioxidant combination therapy for ischemic stroke via glyburide-loaded betulinic acid nanoparticles (2019) (40)
- Quantification of Smoking-Induced Occupancy of β2-Nicotinic Acetylcholine Receptors: Estimation of Nondisplaceable Binding (2010) (39)
- Noninvasive estimation of the aorta input function for measurement of tumor blood flow with [/sup 15/O] water (2001) (39)
- High-resolution imaging of brain 5-HT 1B receptors in the rhesus monkey using [11C]P943. (2010) (39)
- Decreased norepinephrine transporter availability in obesity: Positron Emission Tomography imaging with (S,S)-[11C]O-methylreboxetine (2014) (39)
- Imaging signal transduction via arachidonic acid in the human brain during visual stimulation, by means of positron emission tomography (2007) (39)
- Data-driven event-by-event respiratory motion correction using TOF PET list-mode centroid of distribution (2017) (38)
- Dose-Related Target Occupancy and Effects on Circuitry, Behavior, and Neuroplasticity of the Glycine Transporter-1 Inhibitor PF-03463275 in Healthy and Schizophrenia Subjects (2018) (38)
- Event-by-Event Continuous Respiratory Motion Correction for Dynamic PET Imaging (2016) (37)
- Elevated Dopamine D2/3 Receptor Availability in Obese Individuals: A PET Imaging Study with [11C](+)PHNO (2016) (37)
- Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [11C]PBR28 HRRT PET study (2019) (37)
- Microglial depletion and activation: A [11C]PBR28 PET study in nonhuman primates (2017) (37)
- Determination of the In Vivo Selectivity of a New κ-Opioid Receptor Antagonist PET Tracer 11C-LY2795050 in the Rhesus Monkey (2013) (37)
- Guidelines for the content and format of PET brain data in publications and archives: A consensus paper (2020) (37)
- Association of Aβ deposition and regional synaptic density in early Alzheimer’s disease: a PET imaging study with [11C]UCB-J (2021) (36)
- Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer’s Disease (2017) (36)
- Studies of the metabotropic glutamate receptor 5 radioligand [11C]ABP688 with N‐acetylcysteine challenge in rhesus monkeys (2013) (36)
- Evaluation of bias and variance in low-count OSEM list mode reconstruction (2015) (36)
- Multiple-Radionuclide Autoradiography in Evaluation of Cerebral Function (1984) (35)
- Age-related changes in binding of the D2/3 receptor radioligand [11C](+)PHNO in healthy volunteers (2016) (35)
- Direct 4D list mode parametric reconstruction for PET with a novel EM algorithm (2008) (35)
- Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics (2019) (35)
- Parametric Imaging With PET and SPECT (2020) (35)
- In vivo evidence of lower synaptic vesicle density in schizophrenia (2021) (35)
- Count-Rate Dependent Component-Based Normalization for the HRRT (2007) (35)
- Parametric Imaging and Test–Retest Variability of 11C-(+)-PHNO Binding to D2/D3 Dopamine Receptors in Humans on the High-Resolution Research Tomograph PET Scanner (2014) (34)
- Evaluation of 11C-BU99008, a PET Ligand for the Imidazoline2 Binding Sites in Rhesus Brain (2014) (34)
- Hyperosmolar blood-brain barrier disruption in baboons: an in vivo study using positron emission tomography and rubidium-82. (1996) (34)
- Imaging of cerebral α4β2* nicotinic acetylcholine receptors with (−)-[18F]Flubatine PET: Implementation of bolus plus constant infusion and sensitivity to acetylcholine in human brain (2016) (34)
- Test–retest reproducibility of the metabotropic glutamate receptor 5 ligand [18F]FPEB with bolus plus constant infusion in humans (2015) (34)
- Differential effects of paroxetine on raphe and cortical 5-HT1A binding: A PET study in monkeys (2005) (34)
- Amphetamine-Induced Dopamine Release (2001) (33)
- OCD is associated with an altered association between sensorimotor gating and cortical and subcortical 5-HT1b receptor binding. (2016) (33)
- In vivo muscarinic binding of 3‐(alkylthio)‐3‐thiadiazolyl tetrahydropyridines (1999) (33)
- Evaluation of [11C]MRB for assessment of occupancy of norepinephrine transporters: Studies with atomoxetine in non-human primates (2011) (33)
- Quantification of myocardial blood flow with 82Rb: Validation with 15O-water using time-of-flight and point-spread-function modeling (2016) (33)
- Human Positron Emission Tomography Neuroimaging. (2019) (33)
- Determination of In Vivo Bmax and Kd for 11C-GR103545, an Agonist PET Tracer for κ-Opioid Receptors: A Study in Nonhuman Primates (2013) (31)
- First-in-Human Evaluation of 18F-SynVesT-1, a Radioligand for PET Imaging of Synaptic Vesicle Glycoprotein 2A (2020) (31)
- Imaging Changes in Synaptic Acetylcholine Availability in Living Human Subjects (2013) (30)
- Brain glucose metabolism in noninsulin-dependent diabetes mellitus: a study in Pima Indians using positron emission tomography during hyperinsulinemia with euglycemic glucose clamp. (1990) (30)
- Synthesis and in vivo evaluation of [18F]UCB-J for PET imaging of synaptic vesicle glycoprotein 2A (SV2A) (2019) (30)
- Optimization of Noninvasive Activation Studies with 15O-Water and Three-Dimensional Positron Emission Tomography (1997) (30)
- High Single Doses of Radiation May Induce Elevated Levels of Hypoxia in Early-Stage Non-Small Cell Lung Cancer Tumors. (2018) (30)
- Reduced post-synaptic serotonin type 1A receptor binding in bipolar depression (2013) (30)
- Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits (2016) (28)
- Experimentally reducing corticosterone mitigates rapid captivity effects on behavior, but not body composition, in a wild bird (2017) (28)
- Ex vivo and in vivo evaluation of the norepinephrine transporter ligand [11C]MRB for brown adipose tissue imaging. (2012) (28)
- Regional and source-based patterns of [11C]-(+)-PHNO binding potential reveal concurrent alterations in dopamine D2 and D3 receptor availability in cocaine-use disorder (2017) (27)
- Optimization of PET–MR registrations for nonhuman primates using mutual information measures: A Multi-Transform Method (MTM) (2013) (27)
- Relationship Between Glycine Transporter 1 Inhibition as Measured with Positron Emission Tomography and Changes in Cognitive Performances in Nonhuman Primates (2014) (27)
- Investigation of a Technique for Providing a Pseudo-Continuous Detector Ring for Positron Tomography (1982) (27)
- Non-Rigid Event-by-Event Continuous Respiratory Motion Compensated List-Mode Reconstruction for PET (2018) (26)
- Women can bear a bigger burden: ante- and post-mortem evidence for reserve in the face of tau (2020) (26)
- Scatter correction in maximum-likelihood reconstruction of PET data (1992) (26)
- A Potential Cholinergic Mechanism of Procaine's Limbic Activation* (2004) (26)
- Event-by-event respiratory motion correction for PET with 3D internal-1D external motion correlation. (2013) (26)
- First-in-Human Assessment of the Novel PDE2A PET Radiotracer 18F-PF-05270430 (2016) (26)
- In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation (2019) (25)
- Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease (2021) (25)
- Determination of [18F]FCWAY, [18F]FP-TZTP, and their metabolites in plasma using rapid and efficient liquid-liquid and solid phase extractions. (2003) (25)
- Determination of receptor occupancy in the presence of mass dose: [11C]GSK189254 PET imaging of histamine H3 receptor occupancy by PF-03654746 (2017) (25)
- Data-driven voluntary body motion detection and non-rigid event-by-event correction for static and dynamic PET (2019) (25)
- Comparison of [11C]UCB-J and [18F]FDG PET in Alzheimer’s disease: A tracer kinetic modeling study (2021) (24)
- Assessment of population-based input functions for Patlak imaging of whole body dynamic 18F-FDG PET (2020) (24)
- Age Effects on Serotonin Receptor 1B as Assessed by PET (2012) (24)
- Synthesis and Preclinical Evaluation of an 18F-Labeled Synaptic Vesicle Glycoprotein 2A PET Imaging Probe: [18F]SynVesT-2. (2020) (24)
- Imaging human brown adipose tissue under room temperature conditions with (11)C-MRB, a selective norepinephrine transporter PET ligand. (2015) (24)
- Higher in vivo muscarinic-2 receptor distribution volumes in aging subjects with an apolipoprotein E-epsilon4 allele. (2003) (24)
- Kappa opioid receptor binding in major depression: A pilot study (2018) (24)
- Preliminary in vivo evidence of lower hippocampal synaptic density in cannabis use disorder (2020) (23)
- 2181 Age-related change in 5-HT6 receptor availability in healthy male volunteers measured with 11C-GSK215083 PET (2018) (23)
- Dopamine D 3 Receptor Alterations in Cocaine-Dependent Humans Imaged with [ 11 C](+)PHNO (2014) (23)
- Assessing the sensitivity of [11C]p943, a novel 5‐HTIB radioligand, to endogenous serotonin release (2011) (23)
- Effect of smoothing during transmission processing on quantitative cardiac PET scans. (1996) (23)
- Cerebral glucose metabolic rates after 30 and 45 minute acquisitions: a comparative study. (1992) (23)
- Quantitative comparison of cerebral glucose metabolic rates from two positron emission tomographs. (1989) (23)
- A multimodal approach to image-derived input functions for brain PET (2009) (22)
- Tobacco smoking interferes with GABAA receptor neuroadaptations during prolonged alcohol withdrawal (2014) (21)
- Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies. (2009) (21)
- 18F-florbetapir Positron Emission Tomography–determined Cerebral &bgr;-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery (2018) (21)
- A Novel Loss Function Incorporating Imaging Acquisition Physics for PET Attenuation Map Generation using Deep Learning (2019) (21)
- Quantitative PET Imaging in Drug Development: Estimation of Target Occupancy (2019) (21)
- PET imaging evaluation of [18F]DBT-10, a novel radioligand specific to α7 nicotinic acetylcholine receptors, in nonhuman primates (2016) (21)
- Binding of the synaptic vesicle radiotracer [11C]UCB-J is unchanged during functional brain activation using a visual stimulation task (2020) (21)
- Comparison of PET [15O]Water Studies with 6-Minute and 10-Minute InterScan Intervals: Single-Subject and Group Analyses (1999) (21)
- Awake Nonhuman Primate Brain PET Imaging with Minimal Head Restraint: Evaluation of GABAA-Benzodiazepine Binding with 11C-Flumazenil in Awake and Anesthetized Animals (2013) (20)
- A click-chemistry based strategy for labeling an anti-phosphatidylserine (PS) antibody with copper-64 via a cross-bridged tetraazamacrocyclic chelator scaffold (2014) (20)
- PET imaging of mGluR5 in Alzheimer’s disease (2020) (20)
- Cortical β-amyloid burden, gray matter, and memory in adults at varying APOE ε4 risk for Alzheimer's disease (2018) (20)
- Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer’s Disease via Fusion of Clinical, Imaging and Omic Features (2017) (20)
- Noninvasive Estimation of Normalized Distribution Volume: Application to the Muscarinic-2 Ligand [18F]FP-TZTP (2008) (20)
- Evaluation of PET Brain Radioligands for Imaging Pancreatic β-Cell Mass: Potential Utility of 11C-(+)-PHNO (2018) (20)
- Software architecture of the MOLAR-HRRT reconstruction engine (2004) (20)
- Evaluation of Pancreatic VMAT2 Binding with Active and Inactive Enantiomers of [18F]FP-DTBZ in Healthy Subjects and Patients with Type 1 Diabetes (2018) (19)
- A preliminary study of dopamine D2/3 receptor availability and social status in healthy and cocaine dependent humans imaged with [(11)C](+)PHNO. (2015) (19)
- Positron Emission Tomography [15O]Water Studies with Short InterScan Interval for Single-Subject and Group Analysis: Influence of Background Subtraction (1998) (19)
- Social status and demographic effects of the kappa opioid receptor: a PET imaging study with a novel agonist radiotracer in healthy volunteers (2019) (19)
- First-in-Human Assessment of 11C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer (2020) (19)
- KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease (2021) (19)
- A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data (2019) (19)
- Further evaluation of [11C]MP‐10 as a radiotracer for phosphodiesterase 10A: PET imaging study in rhesus monkeys and brain tissue metabolite analysis (2015) (19)
- Evaluation of the sensitivity of the novel α4β2* nicotinic acetylcholine receptor PET radioligand 18F‐(‐)‐NCFHEB to increases in synaptic acetylcholine levels in rhesus monkeys (2014) (18)
- In hot blood: quantifying the arterial input function. (2013) (18)
- Assessment of a three-dimensional line-of-response probability density function system matrix for PET (2012) (18)
- Initial evaluation of direct 4D parametric reconstruction with human PET data (2009) (18)
- In Vivo Imaging of Insulin Receptors in Monkeys Using 18F-Labeled Insulin and Positron Emission Tomography (1992) (18)
- Quantitative accuracy of HRRT lIST-MODE reconstructions: Effect of low statistics (2008) (18)
- Quantitative Analysis of Dynamic 123I-mIBG SPECT Imaging Data in Healthy Humans with a Population-Based Metabolite Correction Method (2016) (18)
- Decreased VMAT2 in the pancreas of humans with type 2 diabetes mellitus measured in vivo by PET imaging (2018) (18)
- Investigation of angular smoothing of PET data (1997) (17)
- Age and APOE‐ϵ4 genotype influence the effect of physostigmine infusion on the in‐vivo distribution volume of the muscarinic‐2‐receptor dependent tracer [18F]FP‐TZTP (2006) (17)
- Whole body PET using overlapped 3D acquisition and weighted image summation (1996) (17)
- Evaluation of 11C-LSN3172176 as a Novel PET Tracer for Imaging M1 Muscarinic Acetylcholine Receptors in Nonhuman Primates (2019) (17)
- Preliminary In Vivo Evidence of Reduced Synaptic Density in Human Immunodeficiency Virus (HIV) Despite Antiretroviral Therapy (2021) (17)
- Quantification of SV2A Binding in Rodent Brain Using [18F]SynVesT-1 and PET Imaging (2020) (17)
- Data-Driven Motion Detection and Event-by-Event Correction for Brain PET: Comparison with Vicra (2020) (17)
- Noradrenergic Activity in the Human Brain: A Mechanism Supporting the Defense Against Hypoglycemia (2018) (17)
- An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of 11C-LY2459989 (2014) (17)
- Analysis of Covariance in Statistical Parametric Mapping (1993) (16)
- A Realistic Computer-Simulated Brain Phantom for Evaluation of PET Charactenstics (1987) (16)
- Estradiol modulates neural response to conspecific and heterospecific song in female house sparrows: An in vivo positron emission tomography study (2017) (16)
- Plasma phosphorylated-tau181 as a predictive biomarker for Alzheimer’s amyloid, tau and FDG PET status (2021) (16)
- PET-BIDS, an extension to the brain imaging data structure for positron emission tomography (2021) (16)
- Quantification of Tumor Hypoxic Fractions Using Positron Emission Tomography with [18F]Fluoromisonidazole ([18F]FMISO) Kinetic Analysis and Invasive Oxygen Measurements (2017) (16)
- Kinetic Analysis of Drug–Target Interactions with PET for Characterization of Pharmacological Hysteresis (2013) (16)
- Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways (2016) (16)
- Evaluation of pancreatic VMAT2 binding with active and inactive enantiomers of 18F-FP-DTBZ in baboons. (2016) (15)
- In vivo muscarinic binding selectivity of (R,S)- and (R,R)-[18F]-fluoromethyl QNB. (1997) (15)
- Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer’s Dementia (2018) (15)
- Test-retest reproducibility of [11C]-(+)-propyl-hexahydro-naphtho-oxazin positron emission tomography using the bolus plus constant infusion paradigm. (2013) (15)
- Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11C]UCB‐J (2022) (15)
- Accuracy of head motion compensation for the HRRT: Comparison of methods (2009) (14)
- Using single photon emission tomography (SPECT) and positron emission tomography (PET) to trace the distribution of muscarinic acetylcholine receptor (MACHR) binding radioligands. (1999) (14)
- Tracer Kinetic Modeling of [11C]AFM, a New PET Imaging Agent for the Serotonin Transporter (2008) (14)
- Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose (2018) (14)
- Assessment of test-retest reproducibility of [18F]SynVesT-1, a novel radiotracer for PET imaging of synaptic vesicle glycoprotein 2A (2021) (14)
- Synthesis and evaluation of an 18F analog of forskolin for imaging adenylyl cyclase (2000) (14)
- Direct reconstruction of parametric images for brain PET with event-by-event motion correction: evaluation in two tracers across count levels (2017) (14)
- Opiate receptor avidity is reduced in non-motor impaired MPTP-lesioned rhesus monkeys (1998) (14)
- Device-dependent activity estimation and decay correction of radionuclide mixtures with application to Tc-94m PET studies. (2001) (13)
- Norepinephrine transporter availability in brown fat is reduced in obesity: a human PET study with [11C] MRB (2019) (13)
- In vivo 5-HT6 and 5-HT2A receptor availability in antipsychotic treated schizophrenia patients vs. unmedicated healthy humans measured with [11C]GSK215083 PET (2019) (13)
- Evaluation of Frame-Based and Event-by-Event Motion-Correction Methods for Awake Monkey Brain PET Imaging (2014) (13)
- Evaluation of [(18)F]-(-)-norchlorofluorohomoepibatidine ([(18)F]-(-)-NCFHEB) as a PET radioligand to image the nicotinic acetylcholine receptors in non-human primates. (2015) (13)
- Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme (2016) (13)
- Test–retest reliability of the novel 5-HT1B receptor PET radioligand [11C]P943 (2015) (13)
- Randoms estimation for list-mode reconstruction for the ECAT HRRT (2004) (13)
- Evaluation of the Lysophosphatidic Acid Receptor Type 1 Radioligand 11C-BMT-136088 for Lung Imaging in Rhesus Monkeys (2017) (13)
- Brain-Dedicated Emission Tomography Systems: A Perspective on Requirements for Clinical Research and Clinical Needs in Brain Imaging (2019) (12)
- A semi-mechanism approach based on MRI and proteomics for prediction of conversion from mild cognitive impairment to Alzheimer’s disease (2016) (12)
- Arterial blood concentration curves by cardiac PET without arterial sampling or image reconstruction (1988) (12)
- Glia Imaging Differentiates Multiple System Atrophy from Parkinson's Disease: A Positron Emission Tomography Study with [11C]PBR28 and Machine Learning Analysis (2021) (12)
- PET Imaging of Pancreatic Dopamine D2 and D3 Receptor Density with 11C-(+)-PHNO in Type 1 Diabetes (2020) (12)
- Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study (2021) (12)
- Event-by-event non-rigid data-driven PET respiratory motion correction methods: comparison of principal component analysis and centroid of distribution (2019) (11)
- Opiate receptor avidity in the thalamus is sexually dimorphic in the elderly (2000) (11)
- Cerebral Metabolic Effects of Intravenous Glycine in Healthy Human Subjects (2006) (11)
- Bolus Injection versus Slow Infusion of [15O]Water for Positron Emission Tomography Activation Studies (1999) (11)
- emission tomography in nonhuman primates (2012) (11)
- Simplified Quantification of 11C-UCB-J PET Evaluated in a Large Human Cohort (2020) (11)
- The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum (2016) (10)
- Improved quantification for Tc-94 m PET imaging (2000) (10)
- Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q (2022) (10)
- Binding to Metabotropic Glutamate Receptor Subtype 5 (2014) (10)
- Generation of parametric Ki images for FDG PET using two 5-min scans. (2021) (10)
- Local molecular and global connectomic contributions to cross-disorder cortical abnormalities (2022) (10)
- Measurement of transferrin receptor kinetics in the baboon liver using dynamic positron emission tomography imaging and [18F]holo‐transferrin (1997) (10)
- Consensus nomenclature: its time has come (2007) (10)
- In vivo synaptic density imaging with 11 C-UCB-J detects treatment effects of saracatinib (AZD0530) in a mouse model of Alzheimer’s disease. (2019) (9)
- Opiate receptor avidity is reduced bilaterally in rhesus monkeys unilaterally lesioned with MPTP (1999) (9)
- Measuring the effects of ketamine on mGluR5 using [18F]FPEB and PET (2019) (9)
- FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease (2020) (9)
- Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease (2022) (9)
- Event-by-event respiratory motion correction for PET with 3-Dimensional internal-external motion correlation (2012) (9)
- Direct EM reconstruction of kinetic parameters from list-mode cardiac PET (2014) (9)
- [11C]Methionine and [11C]PBR28 as PET Imaging Tracers to Differentiate Metastatic Tumor Recurrence or Radiation Necrosis (2020) (9)
- Brivaracetam enters the brain faster than levetiracetam: a PET study in healthy volunteers (P6.233) (2017) (9)
- Identifying brain networks in synaptic density PET (11C-UCB-J) with independent component analysis (2021) (9)
- A metabolically stable PET tracer for imaging synaptic vesicle protein 2A: synthesis and preclinical characterization of [18F]SDM-16 (2021) (8)
- Human adult and adolescent biodistribution and dosimetry of the synaptic vesicle glycoprotein 2A radioligand 11C-UCB-J (2020) (8)
- The Search for a Subtype-Selective PET Imaging Agent for the GABAA Receptor Complex: Evaluation of the Radiotracer [11C]ADO in Nonhuman Primates (2017) (8)
- Applications of the line-of-response probability density function resolution model in PET list mode reconstruction (2015) (8)
- Tracer kinetic parametric imaging in PET (2004) (8)
- Chapter 36 - Absolute Cerebral Blood Flow with [ 15 O]Water and PET: Determination Without a Measured Input Function (1996) (8)
- Measurement of Bmax and Kd with the Glycine Transporter 1 Radiotracer 18F-MK6577 using a Novel Multi-Infusion Paradigm (2015) (8)
- First in-human PET study and kinetic evaluation of [18F]AS2471907 for imaging 11β-hydroxysteroid dehydrogenase type 1 (2020) (8)
- [11C]PHNO studies in rhesus monkey: In vivo affinity for D2 and D3 receptors and dosimetry (2009) (8)
- Scatchard Analysis with Bolus/Infusion Administration of [11C]Raclopride (2002) (8)
- Investigation of Sub-Centimeter Lung Nodule Quantification for Low-Dose PET (2018) (8)
- Multimodal investigation of dopamine D2/D3 receptors, default mode network suppression, and cognitive control in cocaine-use disorder (2020) (8)
- A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease (2020) (8)
- Cardiac‐gated parametric images from 82Rb PET from dynamic frames and direct 4D reconstruction (2018) (8)
- Kinetic modeling of the kappa agonist tracer [11C]GR103545 in humans (2010) (8)
- Can partial volume effects be used to measure myocardial thickness and thickening? (1992) (8)
- Kinetic Modeling and Test–Retest Reproducibility of 11C-EKAP and 11C-FEKAP, Novel Agonist Radiotracers for PET Imaging of the κ-Opioid Receptor in Humans (2020) (8)
- PET Imaging of Synaptic Vesicle Protein 2A (2020) (8)
- Cerebral blood flow in temporal lobe epilepsy: a partial volume correction study (2007) (8)
- Partial volume correction analysis for 11C-UCB-J PET studies of Alzheimer’s disease (2021) (7)
- Atlas-Based Multiorgan Segmentation for Dynamic Abdominal PET (2020) (7)
- Lower prefrontal cortical synaptic vesicle binding in cocaine use disorder: An exploratory 11C‐UCB‐J positron emission tomography study in humans (2021) (7)
- Inhibition of hypoxic pulmonary vasoconstriction by diphenyleneiodoniumVol. 42 (1991) R9-R12 (1991) (7)
- Correlation between Alzheimer’s disease and type 2 diabetes using non-negative matrix factorization (2021) (7)
- A predictive model using the mesoscopic architecture of the living brain to detect Alzheimer’s disease (2022) (7)
- Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold. (2021) (7)
- Age and sex effects on synaptic density in healthy humans as assessed with SV2A PET (2018) (7)
- Evaluation of (‐)‐[18F]Flubatine‐specific binding: Implications for reference region approaches (2018) (7)
- List-mode reconstruction for the Biograph mCT with probabilistic line-of-response positioning and event-by-event motion correction (2012) (7)
- Investigation of angular and axial smoothing of PET data (1996) (6)
- Assessment of population-based input functions for the Patlak plot using whole body 18F-FDG PET imaging (2019) (6)
- Molecular and connectomic vulnerability shape cross-disorder cortical abnormalities (2022) (6)
- Data-driven respiratory motion estimation and correction using TOF PET list-mode centroid of distribution (2014) (6)
- Count-rate dependent resolution degradation from pulse pile-up on the HRRT (2010) (6)
- Effect of subsets on bias and variance in low-count iterative PET reconstruction (2013) (6)
- A kinetic comparison of [18F]2-fluoro-2-deoxyglucose and [18F]2-fluoro-2-deoxymannose using positron emission tomography. (1994) (6)
- Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume (2022) (6)
- PET H2 15O activation studies using a short interscan interval and background-subtraction technique (1996) (6)
- Predicting Alzheimer’s disease progression using multi-modal deep learning approach (2019) (6)
- Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference (2018) (6)
- Synthesis and evaluation of 18F-UCB-H, a novel PET imaging tracer for the synaptic vesicle protein 2A (2014) (6)
- Absolute cerebral blood flow with /sup 15/O-water and PET: determination without a measured input function (1994) (6)
- Tobacco Smoking in People Is Not Associated with Altered 18-kDa Translocator Protein Levels: A PET Study (2020) (6)
- Binding to D 2 /D 3 Dopamine Receptors in Humans on the High-Resolution Research Tomograph PET Scanner (2014) (6)
- Evaluation of (rac)-, (R)-, and (S)-18F-OF-NB1 for Imaging GluN2B Subunit–Containing N-Methyl-d-Aspartate Receptors in Nonhuman Primates (2022) (6)
- Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease (2022) (6)
- Effect of age on brain metabotropic glutamate receptor subtype 5 measured with [18F]FPEB PET (2021) (5)
- Subcortical D3/D2 receptor binding in cocaine dependent humans (2011) (5)
- Acute neuroimmune stimulation impairs verbal memory in adults: A PET brain imaging study (2020) (5)
- Axial slice width in 3D PET: characterization and potential improvement with axial interleaving. (1998) (5)
- The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory (2019) (5)
- Noise reduction in PET attenuation correction by maximum likelihood histogram sharpening of attenuation images. (1996) (5)
- Determination of regional blood-tissue transfer constants and initial (plasma) volume in brain and brain tumors using 68Ga-EDTA and dynamic positron emission tomography (1984) (5)
- Comparison of PET [15O]Water Studies with 6- and 10-Minute InterScan Intervals: Single-Subject and Group Analyses (1998) (5)
- Body Mass Index and Age Effects on Brain 11β-Hydroxysteroid Dehydrogenase Type 1: a Positron Emission Tomography Study (2020) (5)
- Feasibility study of PET dynamic imaging of [18F]DHMT for quantification of reactive oxygen species in the myocardium of large animals (2020) (5)
- An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease (2022) (5)
- Quantitative projection of human brain penetration of the H3 antagonist PF-03654746 by integrating rat-derived brain partitioning and PET receptor occupancy (2017) (5)
- Altered Cerebral -Aminobutyric Acid Type A–Benzodiazepine Receptor Binding in Panic Disorder Determined by [C]Flumazenil Positron Emission Tomography (2008) (5)
- Evaluation of 11 C-BU99008, a Positron Emission Tomography ligand for the Imidazoline 2 binding sites in Rhesus brain (2013) (5)
- Direct List Mode Parametric Reconstruction for Dynamic Cardiac SPECT (2020) (5)
- Development of a lysophosphatidic acid receptor 1 (LPA1) radioligand for lung imaging with PET (2014) (5)
- Modeling Methods for the Determination of Dopamine Release with [11C]Raclopride and Constant Infusion (1998) (5)
- Validation of the spatially variant probability density functions for the HRRT (2011) (5)
- The serotonin transporter tracer [C-11]AFM provides high specific binding signals in humans (2008) (5)
- [11C]UCB-J: A novel PET tracer for imaging the synaptic vesicle glycoprotein 2A (SV2A) (2014) (5)
- Simplified Quantification and Acquisition Protocol for 123I-MIBG Dynamic SPECT (2018) (5)
- Multiple acquisition frame-based motion correction for awake monkey PET imaging (2010) (5)
- In vivo Scatchard analysis of bolus/infusion 5-HT1B studies with [11C]P943: Comparison between SRTM and equilibrium methods (2008) (5)
- Imaging the Enzyme 11β-Hydroxysteroid Dehydrogenase Type 1 with PET: Evaluation of the Novel Radiotracer 11C-AS2471907 in Human Brain (2019) (5)
- Inverse changes in raphe and cortical 5-HT1B receptor availability after acute tryptophan depletion in healthy human subjects. (2020) (5)
- Nicotine and Nicotine Abstinence Do Not Interfere with GABAA Receptor Neuroadaptations During Alcohol Abstinence. (2016) (5)
- Effects of time delay in cardiac blood flow measurements by bolus H/sub 2//sup 15/O (1997) (5)
- Opiate receptor avidity is increased in rhesus monkeys following unilateral optic tract lesion combined with transections of corpus callosum and hippocampal and anterior commissures (2000) (4)
- PET Imaging of Synaptic Density: Challenges and Opportunities of Synaptic Vesicle Glycoprotein 2A PET in Small Animal Imaging (2022) (4)
- A maximum likelihood method for calculation of tomographic region-of-interest (ROI) values (1985) (4)
- Comparative study of two glycine transporter 1 radiotracers [11C]GSK931145 and [18F]MK6577 in baboons (2013) (4)
- Direct, Quantitative, and Noninvasive Imaging of the Transport of Active Agents Through Intact Brain with Positron Emission Tomography (2013) (4)
- Separating dopamine D2 and D3 receptor sources of [11C]-(+)-PHNO binding potential: Independent component analysis of competitive binding (2020) (4)
- Tracer Kinetic Modeling in Positron Computed Tomography (1983) (4)
- Generation of Synthetic PET Images of Synaptic Density and Amyloid from 18 F-FDG Images Using Deep Learning. (2021) (4)
- Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients (2022) (4)
- Brain PET dose reduction using a shallow artificial neural network (2018) (4)
- First-in-Human study of [18F]SynVesT-2, a novel SV2A radioligand with fast kinetics and high specific binding signals (2020) (4)
- First in Human Assessment of the Novel M1 Muscarinic Acetylcholine Receptor PET Radiotracer 11C-LSN3172176 Authors:Mika Naganawa1,Nabeel Nabulsi1,Shannan Henry1,David Matuskey1,Shu-fei Lin1, (2020) (4)
- PET studies of frontal lobe function during cognition (1991) (4)
- Abdominal multi-organ segmentation of dynamic PET studies using modified fuzzy clustering algorithm (2015) (4)
- Short Communication Assessing the Sensitivity of ( 11 C)P943, a Novel 5-HT IB Radioligand, to Endogenous Serotonin Release (2011) (4)
- Characterization in nonhuman primates of (R)-[18F]OF-Me-NB1 and (S)-[18F]OF-Me-NB1 for imaging the GluN2B subunits of the NMDA receptor (2021) (4)
- Whither water? (1994) (4)
- Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts (2016) (4)
- Uniform Spatial resolution list mode reconstruction for the HRRT (2012) (4)
- Assessment of kinetic modeling quality of fit by cluster analysis of residuals: Application to direct reconstruction of cardiac PET data (2015) (4)
- Human PET studies with [18F]PF-05270430, a PET radiotracer for imaging phosphodiesterase-2A (2013) (4)
- Receptor Occupancy of the k-Opioid Antagonist LY 2456302 Measured with Positron Emission Tomography and the Novel Radiotracer 11 CLY 2795050 (2016) (3)
- CEREBRAL GLUCOSE METABOLISM AS A FUNCTION OF AGE: THE INFLUENCE OF THE RATE CONSTANTS IN THE FDG METHOD (1982) (3)
- Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology (2020) (3)
- Comparison of three novel radiotracers for GluN2B-containing NMDA receptors in non-human primates: (R)-[11C]NR2B-Me, (R)-[18F]of-Me-NB1, and (S)-[18F]of-NB1 (2022) (3)
- Feasible uniform-resolution penalized likelihood reconstruction for static- and multi-frame 3D PET (2013) (3)
- Kinetic modeling of CB1 PET tracer [11C]OMAR in rhesus monkeys and humans (2010) (3)
- Imaging brain cortisol regulation in PTSD with a target for 11β-hydroxysteroid dehydrogenase type 1. (2021) (3)
- Quantification of normal pattern of regional myocardial uptake of 18F LMI1195, a novel tracer for imaging myocardial sympathetic function: First-in-human study (2010) (3)
- In vivo imaging of D2 receptors and corticosteroids predict behavioural responses to captivity stress in a wild bird (2019) (3)
- Clinical and scientific value in the pursuit of quantification of beta cells in the pancreas by PET imaging (2018) (3)
- 18F-SDM-8: A novel radiotracer for PET imaging of synaptic density (2018) (3)
- Effects of time delay in cardiac blood flow measurements by bolus H2(15)O. (1997) (3)
- First-in-human evaluation of 18 F-SynVesT-1, a novel radioligand for PET imaging of synaptic vesicle protein 2A (2020) (3)
- Translational receptor occupancy for the 5-HT4 partial agonist PF-04995274 in rats, non-human primates and healthy volunteers (2011) (3)
- First-inHuman Assessment of the Novel PDE 2 A PET Radiotracer 18 FPF-05270430 (2016) (3)
- A 3D-printed modular device for imaging the brain of small birds (2018) (3)
- Imaging of Synaptic Density in Neurodegenerative Disorders. (2022) (3)
- III. Biomathematical Aspects of Physiological Brain Imaging (1987) (3)
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- Quantification of PET infusion studies without true equilibrium: A tissue clearance correction (2020) (3)
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- In Vivo [11C]PBR28 PET Imaging in Multiple Sclerosis: A Reproducibility Study at High Resolution (PD6.010) (2013) (1)
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- Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states (2018) (0)
- The trend of disruption in the functional brain network topology of Alzheimer’s disease (2021) (0)
- Amyloid-ß burden and neuropsychological test performance in cognitively normal first-degree relatives at varying genetic risk for Alzheimer's disease (2011) (0)
- A comparative study of 18F-ASEM and 18F-DBT-10, two novel PET tracers for the α7 nicotinic acetylcholine receptor in nonhuman primates (2015) (0)
- Test-retest variability of the H3 receptor antagonist [11C]GSK189254 (2010) (0)
- Novel Use of Agent 11C-PHNO for Pet CT Imaging of Pancreatic Beta-Cell Mass (2018) (0)
- Imaging the Effect of Ketamine on Synaptic (SV2A) Density (2021) (0)
- Partial volume correction for PET synaptic density imaging with 11C-UCB-J (2018) (0)
- A new F-18 labeled PET tracer for the norepinephrine transporter (2012) (0)
- List-mode reconstruction for the FOCUS-220 with motion correction: Application to awake nonhuman primate imaging (2011) (0)
- P95. Cortical Amyloid Burden is Associated With Basal Forebrain but Not Medial Temporal Lobe Atrophy in Adults at Varying APOE ɛ4 Risk for Alzheimer’s Disease (2022) (0)
- Activated microglia imaging in patients with multiple sclerosis using [11C]PBR28 and high resolution PET: Test-retest reliability (2013) (0)
- Modulation of cerebral functional interactions by cortical dopamine in health and Parkinson's disease (2007) (0)
- Awake Monkey Brain PET Imaging Evaluation of Frame-Based and Event-by-Event Motion-Correction Methods for (2014) (0)
- Radiosynthesis and in vivo evaluation in the pig and baboon of candidate PDE10A PET radioligands (2013) (0)
- Imaging brown fat in humans with 11C-MRB, a selective norepinephrine transporter PET ligand (2014) (0)
- Association between cerebrospinal fluid biomarkers of neurodegeneration and PET measurements of synaptic density in Alzheimer’s disease (2020) (0)
- Neurotransmitter transporter occupancy following administration of centanafadine sustained-release tablets: A phase 1 study in healthy male adults (2022) (0)
- WE-G-BRD-06: Variation in Dynamic Positron Emission Tomography Imaging of Tumor Hypoxia in Early Stage Non-Small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy. (2014) (0)
- A OF A NOVEL F-LABELED PET TRACER FOR IMAGING ASTROGLIOSIS (2019) (0)
- Use of spatially-variant probability density functions in list-mode reconstruction for the HRRT (2012) (0)
- Assessment of gray matter microstructure and synaptic density in Alzheimer’s Disease: a multimodal imaging study with DWI and SV2A PET (2022) (0)
- Super-resolution PET Brain Imaging using Deep Learning (2021) (0)
- 11C‐PBR28 brain PET imaging with lipopolysaccharide challenge for the study of microglia function in Alzheimer’s disease (2020) (0)
- Evaluation of established brain radiotracers for imaging pancreatic beta cells in healthy subjects with PET (2016) (0)
- Noninvasive Quantitative PET Imaging in Humans of the Pancreatic Beta-Cell Mass Biomarkers VMAT2 and Dopamine D2/D3 Receptors In Vivo. (2023) (0)
- Imaging drug-induced dopamine release in rhesus monkeys with [11C]PHNO PET (2010) (0)
- Quantitative Accuracy ofHRRT List-mode Reconstructions: Effect ofLow Statistics (2008) (0)
- S13. IN VIVO EVIDENCE OF REDUCED SYNAPTIC VESICLE DENSITY IN SCHIZOPHRENIA USING [11C] UCB-J PET IMAGING (2019) (0)
- A blood-based signature of cerebrospinal fluid Aβ1–42 status (2019) (0)
- PBR28 Brain PET imaging with lipopolysaccharide challenge for the study of microglia function in Alzheimer’s disease (2020) (0)
- PET measurement of nicotine evoked dopamine release (2010) (0)
- Reply: 11C-(+)-PHNO Trapping Reversibility for Quantitative PET Imaging of β-Cell Mass in Patients with Type 1 Diabetes (2020) (0)
- P1-386 PREDICTING BRAIN AMYLOID-b BURDEN WITH ATROPHY IN MCI (2019) (0)
- Modeling of ligand–receptor interactions for a nicotinic agonist: Is it possible to discriminate multiple affinity states in vivo with PET? (2006) (0)
- An objective evaluation method for head motion estimation in PET—Motion corrected centroid-of-distribution (2022) (0)
- Synthesis and Evaluation of an 18F Analogue of Forskolin for Imaging Adenylyl Cyclase. (2000) (0)
- GenEpi: gene-based epistasis discovery using machine learning (2020) (0)
- Serotonin transporter availability in physically aggressive personality disordered patients: associations with trait and state aggression, and response to fluoxetine (2023) (0)
- ASSOCIATION BETWEEN ODOR IDENTIFICATION AND REGIONAL GRAY MATTER IN EARLY PRECLINICAL ALZHEIMER'S DISEASE (2019) (0)
- Experimental endotoxemia and microglial activation: A positron emission tomography study in nonhuman primates (2011) (0)
- Equilibrium analysis of GABAA-benzodiazepine BPND with [11C]flumazenil in awake vs. anesthetized non-human primates (2011) (0)
- Quantitative PET Imaging in Drug Development: Estimation of Target Occupancy (2017) (0)
- Association between cerebral amyloid accumulation and synaptic density in Alzheimer’s disease: A multitracer PET study (2020) (0)
- Synaptic Loss is Associated With Cognitive Impairment in Early Alzheimer’s Disease: A PET Imaging Study With [11C]UCB-J (2021) (0)
- Absolute quantitation of regional myocardial blood flow (MBF) using RB-82 PET: Experimental validation using microspheres (2007) (0)
- Evaluation of bolus and infusion methods for quantification of pancreatic VMAT2 binding using [18F]FP-(+)-DTBZ in humans (2013) (0)
- Constrained methods for kinetic modeling of amphetamine effect in human cortex with [11C]FLB457 (2014) (0)
- Characterization of a PET radioligand suitable for imaging and quantification of sigma-2 receptor in the primate brain (2022) (0)
- Kinetic analysis of the kappa agonist tracer [11C]GR103545 in healthy controls (2010) (0)
- Independent component analysis of synaptic density 11C-UCB-J PET in Alzheimer’s disease identifies networks correlated with cognitive impairment (2020) (0)
- A Comparative Study of Absolute Functional CBF Measurements in Normal Human Brain using PASL MRI and [ O-15 ] water PET (2007) (0)
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