Richard Gaynor

Q: What Schools Are Affiliated With Richard Gaynor

Richard Gaynor is affiliated with the following schools: University of California, San Francisco, University of Texas Southwestern Medical Center, Harvard University

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Richard Gaynor

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Why Is Richard Gaynor Influential?

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According to Wikipedia, Richard B. Gaynor is an American physician specializing in hematology-oncology, educator, drug developer, and business executive. He served as an Associate Professor of Medicine at UCLA School of Medicine for nearly a decade, and subsequently as an endowed Professor of Medicine and Microbiology at the University of Texas Southwestern Medical School prior to joining the pharmaceutical industry in 2002. His research on NF-κB, IκB kinase, and other mechanisms regulating viral and cellular gene expression has been covered in leading subject reviews. He has been a top executive at several pharmaceutical companies, with respect to the development and clinical testing of novel anticancer drugs and cell therapies. For over a decade and a half, he worked at Eli Lilly and Company, where he became the Senior Vice President of Oncology Clinical Development and Medical Affairs in 2013. Gaynor was President of R&D at Neon Therapeutics from 2016 to 2020, when he became the President of BioNTech US, both pharmaceutical companies headquartered in Cambridge, MA. His honors include being elected a member of the American Society for Clinical Investigation, and the Association of American Physicians.

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Richard Gaynor's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer. (2001) (1608)
The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β (1998) (1489)
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs (1995) (698)
The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. (1998) (581)
Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression (2003) (576)
IκB kinases: key regulators of the NF-κB pathway (2004) (553)
Sulindac Inhibits Activation of the NF-κB Pathway* (1999) (486)
TAK1 is Critical for IκB Kinase-mediated Activation of the NF-κB Pathway (2003) (345)
Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells. (2003) (332)
Role of the NF-kappaB pathway in the pathogenesis of human disease states. (2001) (312)
Role of the TAB2‐related protein TAB3 in IL‐1 and TNF signaling (2003) (284)
Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression. (2003) (278)
IkappaB kinases: key regulators of the NF-kappaB pathway. (2004) (271)
HTLV-I Tax Protein Binds to MEKK1 to Stimulate IκB Kinase Activity and NF-κB Activation (1998) (269)
Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virus. (1987) (250)
Absolute dependence on kappa B responsive elements for initiation and Tat‐mediated amplification of HIV transcription in blood CD4 T lymphocytes. (1995) (238)
Human immunodeficiency virus type 1 LTR TATA and TAR region sequences required for transcriptional regulation. (1989) (233)
A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer (2020) (231)
Methylation of SPT5 regulates its interaction with RNA polymerase II and transcriptional elongation properties. (2003) (230)
Domains in the SPT5 Protein That Modulate Its Transcriptional Regulatory Properties (2000) (220)
RNA Interference Directed against Viral and Cellular Targets Inhibits Human Immunodeficiency Virus Type 1 Replication (2002) (213)
Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation. (2005) (210)
Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference. (2003) (203)
Sulindac inhibits activation of the NF-kappaB pathway. (1999) (192)
S100 protein is present in cultured human malignant melanomas (1980) (184)
Heat Shock Protein 27 Association with the IκB Kinase Complex Regulates Tumor Necrosis Factor α-induced NF-κB Activation* (2003) (181)
Stimulation of NFκB Activity by Multiple Signaling Pathways Requires PAK1* (2000) (175)
Functional domains required for tat‐induced transcriptional activation of the HIV‐1 long terminal repeat. (1988) (172)
Purification of the human immunodeficiency virus type 1 enhancer and TAR binding proteins EBP‐1 and UBP‐1. (1988) (166)
TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway. (2003) (164)
Identification of NF-κB-regulated genes induced by TNFα utilizing expression profiling and RNA interference (2003) (164)
IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf. (2003) (158)
Role of SP1-binding domains in in vivo transcriptional regulation of the human immunodeficiency virus type 1 long terminal repeat (1989) (154)
S100 PROTEIN: A MARKER FOR HUMAN MALIGNANT MELANOMAS? (1981) (153)
Tat is required for efficient HIV‐1 reverse transcription (1997) (150)
Exclusive Ubiquitination and Sumoylation on Overlapping Lysine Residues Mediate NF-κB Activation by the Human T-Cell Leukemia VirusTax Oncoprotein (2005) (137)
Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction. (2019) (136)
Cis-acting induction of adenovirus transcription (1983) (135)
trans-activation of viral enhancers including long terminal repeat of the human immunodeficiency virus by the hepatitis B virus X protein. (1989) (133)
Expression patterns of immediate early transcription factors in human non-small cell lung cancer. The Lung Cancer Study Group. (1995) (130)
Differential Transcriptional Activation by Human T-Cell Leukemia Virus Type 1 Tax Mutants Is Mediated by Distinct Interactions with CREB Binding Protein and p300 (1998) (128)
Purification of a Tat‐associated kinase reveals a TFIIH complex that modulates HIV‐1 transcription (1997) (122)
Detection of S‐100 protein as an aid to the identification of melanocytic tumors (1982) (118)
Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection. (1984) (117)
Regulation of β-Catenin Function by the IκB Kinases* (2001) (117)
tat regulates binding of the human immunodeficiency virus trans-activating region RNA loop-binding protein TRP-185. (1991) (116)
Regulation of gene expression by HTLV-I Tax protein. (1998) (114)
Protein domains involved in both in vivo and in vitro interactions between human T-cell leukemia virus type I tax and CREB (1995) (112)
TAR independent activation of the human immunodeficiency virus in phorbol ester stimulated T lymphocytes. (1990) (111)
Mechanical force modulates global gene expression and β-catenin signaling in colon cancer cells (2007) (109)
The human T-cell leukemia virus type 1 transactivator protein Tax colocalizes in unique nuclear structures with NF-kappaB proteins (1997) (100)
Identification of NF-kappa B-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference. (2003) (95)
Enhanced Chemosensitivity to Irinotecan by RNA Interference-Mediated Down-Regulation of the Nuclear Factor-κB p65 Subunit (2004) (93)
Role of the human and murine cyclin T proteins in regulating HIV-1 tat-activation. (1999) (93)
Complex formation between CREB and Tax enhances the binding affinity of CREB for the human T-cell leukemia virus type 1 21-base-pair repeats (1996) (93)
Specific binding of a HeLa cell nuclear protein to RNA sequences in the human immunodeficiency virus transactivating region. (1989) (93)
Cloning of a cellular factor, interleukin binding factor, that binds to NFAT-like motifs in the human immunodeficiency virus long terminal repeat. (1991) (93)
Transcription of class III genes activated by viral immediate early proteins. (1985) (91)
A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat. (1990) (88)
Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1. (2000) (86)
Cyclin T1 domains involved in complex formation with Tat and TAR RNA are critical for tat-activation. (1999) (85)
Nuclear Role of IκB Kinase-γ/NF-κB Essential Modulator (IKKγ/NEMO) in NF-κB-dependent Gene Expression* (2004) (81)
Regulation of HIV-1 gene expression by the transactivator protein Tat. (1995) (79)
The TATA homology and the mRNA 5′ untranslated sequence are not required for expression of essential adenovirus E1A functions (1982) (77)
Protein Phosphatase 2Cβ Association with the IκB Kinase Complex Is Involved in Regulating NF-κB Activity* (2003) (77)
A discrete cis element in the human immunodeficiency virus long terminal repeat mediates synergistic trans activation by cytomegalovirus immediate-early proteins (1991) (77)
Role of the human homolog of the yeast transcription factor SPT5 in HIV-1 Tat-activation. (1998) (74)
A Novel CDK9 Inhibitor Shows Potent Antitumor Efficacy in Preclinical Hematologic Tumor Models (2014) (74)
Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B activation. (2003) (74)
HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation. (1998) (73)
Enhanced expression of adenovirus transforming proteins (1982) (72)
Regulation of beta-catenin function by the IkappaB kinases. (2001) (72)
DNA-Dependent Protein Kinase Phosphorylation of IκBα and IκBβ Regulates NF-κB DNA Binding Properties (1998) (71)
A critical role for the TAR element in promoting efficient human immunodeficiency virus type 1 reverse transcription (1996) (69)
Role of IKKγ/NEMO in Assembly of the IκB Kinase Complex* (2000) (66)
Treponema pallidum, lipoproteins, and synthetic lipoprotein analogues induce human immunodeficiency virus type 1 gene expression in monocytes via NF-kappaB activation. (1998) (66)
Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function (1994) (66)
Increased toxicity and lack of efficacy of Rofecoxib in combination with chemotherapy for treatment of metastatic colorectal cancer: A phase II study (2003) (65)
Sequence-based prediction of SARS-CoV-2 vaccine targets using a mass spectrometry-based bioinformatics predictor identifies immunogenic T cell epitopes (2020) (64)
Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular cofactors and Tat. (1995) (63)
Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein ILF. (1992) (61)
Differential role of long terminal repeat control elements for the regulation of basal and Tat-mediated transcription of the human immunodeficiency virus in stimulated and unstimulated primary human macrophages (1994) (60)
Human immunodeficiency virus type 1 and 2 Tat proteins specifically interact with RNA polymerase II. (1996) (58)
Sulindac Enhances Tumor Necrosis Factor-α-mediated Apoptosis of Lung Cancer Cell Lines by Inhibition of Nuclear Factor-κB (2002) (58)
Expression of c-jun during macrophage differentiation of HL-60 cells. (1991) (57)
Phosphorylation of the Human T-Cell Leukemia Virus Type 1 Transactivator Tax on Adjacent Serine Residues Is Critical for Tax Activation (1999) (57)
Regulation of IκB Kinase (IKK)γ/NEMO Function by IKKβ-mediated Phosphorylation* (2002) (56)
IκB Kinase α (IKKα) Regulation of IKKβ Kinase Activity (2000) (55)
IKKγ/NEMO Facilitates the Recruitment of the IκB Proteins into the IκB Kinase Complex* (2001) (55)
Trans-dominant Tat mutants with alterations in the basic domain inhibit HIV-1 gene expression. (1991) (55)
Association of Tat with Purified HIV-1 and HIV-2 Transcription Preinitiation Complexes* (1997) (54)
Cloning and chromosomal mapping of a human immunodeficiency virus 1 "TATA" element modulatory factor. (1992) (53)
HTLV-1 21 bp repeat sequences facilitate stable association between Tax and CREB to increase CREB binding affinity. (1996) (52)
Alterations in binding characteristics of the human immunodeficiency virus enhancer factor (1988) (51)
Chimeric proteins composed of Jun and CREB define domains required for interaction with the human T-cell leukemia virus type 1 Tax protein (1995) (51)
Functional relation between HTLV-II x and adenovirus E1A proteins in transcriptional activation. (1985) (51)
Lymphoid specific gene expression of the adenovirus early region 3 promoter is mediated by NF‐kappa B binding motifs. (1990) (50)
Functional Domains of Tat Required for Efficient Human Immunodeficiency Virus Type 1 Reverse Transcription (1999) (50)
Transcription factor PRDII-BF1 activates human immunodeficiency virus type 1 gene expression (1994) (49)
In Vitro Chromatin Assembly of the HIV-1 Promoter (1997) (49)
Regulatory elements involved in tax-mediated transactivation of the HTLV-I LTR. (1993) (48)
Human T-cell leukemia virus types I and II exhibit different DNase I protection patterns (1988) (46)
Constitutive activation of NF-κB in Ki-ras-transformed prostate epithelial cells (2002) (46)
Analysis of Domains in the IKKα and IKKβ Proteins That Regulate Their Kinase Activity* (2000) (46)
IKKα Regulates the Mitotic Phase of the Cell Cycle by Modulating Aurora A Phosphorylation (2006) (45)
The cellular factor TRP‐185 regulates RNA polymerase II binding to HIV‐1 TAR RNA. (1995) (45)
Differential growth kinetics are exhibited by human immunodeficiency virus type 1 TAR mutants (1994) (45)
Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity. (2004) (45)
Upstream regulatory regions required to stabilize binding to the TATA sequence in an adenovirus early promoter. (1987) (44)
Identification of a Group of Cellular Cofactors That Stimulate the Binding of RNA Polymerase II and TRP-185 to Human Immunodeficiency Virus 1 TAR RNA (*) (1996) (44)
The human immunodeficiency virus type-1 long terminal repeat and its role in gene expression. (1994) (43)
A two-component expression system that responds to inflammatory stimuli in vivo (1997) (43)
Localization of the gene for the DNA-binding protein AP-2 to human chromosome 6p22.3-pter. (1991) (41)
Constitutive Binding of the Transcription Factor Interleukin-2 (IL-2) Enhancer Binding Factor to the IL-2 Promoter* (1997) (41)
Nuclear role of I kappa B Kinase-gamma/NF-kappa B essential modulator (IKK gamma/NEMO) in NF-kappa B-dependent gene expression. (2004) (40)
IKKα Regulates Estrogen-induced Cell Cycle Progression by Modulating E2F1 Expression* (2006) (39)
Absolute dependence on KB responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD 4 T lymphocytes (39)
Regulation of human immunodeficiency virus enhancer function by PRDII-BF1 and c-rel gene products (1992) (38)
Functional Correlates of Mutations in β-Catenin Exon 3 Phosphorylation Sites* (2003) (37)
Multiple transcriptional regulatory domains in the human immunodeficiency virus type 1 long terminal repeat are involved in basal and E1A/E1B-induced promoter activity (1989) (36)
Mechanisms of NF-κB Activation by the HTLV Type 1 Tax Protein (2000) (36)
The Human T-cell Leukemia Virus Type-1 Tax Protein Regulates the Activity of the IκB Kinase Complex* (1999) (36)
Transcription factor AP‐2 activates gene expression of HTLV‐I. (1992) (36)
Genetic mapping of a major site of phosphorylation in adenovirus type 2 E1A proteins (1986) (35)
Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein HTLF. (1992) (33)
Human immunodeficiency virus type 1 TAR element revertant viruses define RNA structures required for efficient viral gene expression and replication (1995) (33)
Assignment of the human gene for CREB1 to chromosome 2q32.3-q34. (1990) (31)
Inhibition of human immunodeficiency virus type 1 replication is enhanced by a combination of transdominant Tat and Rev proteins (1996) (31)
Localization of the gene-encoding upstream stimulatory factor (USF) to human chromosome 1q22-q23. (1993) (29)
CREB regulation of cellular cyclic AMP-responsive and adenovirus early promoters (1990) (29)
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex. (2001) (28)
Tat functions to stimulate the elongation properties of transcription complexes paused by the duplicated TAR RNA element of human immunodeficiency virus 2. (1995) (27)
Correlation of bcl‐2 and p53 expression in primary breast tumors and corresponding metastatic lymph nodes (2003) (27)
IKK alpha regulates estrogen-induced cell cycle progression by modulating E2F1 expression. (2006) (26)
Loss of FHIT Expression in Breast Cancer Is Correlated with Poor Prognostic Markers (2005) (26)
Regulation of NF-kappaB by the HTLV-1 Tax protein. (1999) (25)
Repeated B motifs in the human immunodeficiency virus type I long terminal repeat enhancer region do not exhibit cooperative factor binding. (1988) (25)
Loss of a phosphorylated form of transcription factor CREB/ATF in poliovirus-infected cells (1990) (25)
Regulation of Ikappa B kinase (IKK)gamma /NEMO function by IKKbeta -mediated phosphorylation. (2002) (25)
I-κB Kinases α and β Have Distinct Roles in Regulating Murine T Cell Function1 (2002) (25)
Functional correlates of mutations in beta-catenin exon 3 phosphorylation sites. (2003) (25)
Turning the Tide Against Cancer Through Sustained Medical Innovation: The Pathway to Progress (2014) (24)
I-κB Kinase β Is Critical for B Cell Proliferation and Antibody Response (2002) (23)
Selective identification of secreted and transmembrane breast cancer markers using Escherichia coli ampicillin secretion trap. (2005) (23)
A personal neoantigen vaccine, NEO-PV-01, with anti-PD1 induces broad de novo anti-tumor immunity in patients with metastatic melanoma, NSCLC, and bladder cancer. (2018) (22)
cAMP-response Element-binding Protein Induces Directed DNA Bending of the HTLV-I 21-Base Pair Repeat (*) (1996) (21)
Combined TCR Repertoire Profiles and Blood Cell Phenotypes Predict Melanoma Patient Response to Personalized Neoantigen Therapy plus Anti-PD-1 (2020) (21)
Sequence-based prediction of vaccine targets for inducing T cell responses to SARS-CoV-2 utilizing the bioinformatics predictor RECON (2020) (20)
Sulindac enhances tumor necrosis factor-alpha-mediated apoptosis of lung cancer cell lines by inhibition of nuclear factor-kappaB. (2002) (20)
Analysis of domains in the IKKalpha and IKKbeta proteins that regulate their kinase activity. (2000) (19)
Defining HLA-II ligand processing and binding rules with mass spectrometry enhances cancer epitope prediction. (2021) (18)
Mechanisms of NF-kappaB activation by the HTLV type 1 tax protein. (2000) (16)
Adenovirus early region 3 promoter regulation by E1A/E1B is independent of alterations in DNA binding and gene activation of CREB/ATF and AP1 (1990) (16)
Identification of NF-κB-regulated genes induced by TNFα utilizing expression profiling and RNA interference (2004) (15)
Regulation of HTLV-I gene expression by tax and AP-2. (1992) (15)
I-kappa B kinases alpha and beta have distinct roles in regulating murine T cell function. (2002) (14)
S‐100Protein: A Marker for Melanocytic Tumors a (1983) (14)
Localization of the zinc finger DNA-binding protein HIV-EP1/MBP-1/PRDII-BF1 to human chromosome 6p22.3-p24. (1991) (14)
DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties. (1998) (13)
Intracellular Factors Involved in Gene Expression of Human Retroviruses (1995) (13)
IKKgamma /NEMO facilitates the recruitment of the IkappaB proteins into the IkappaB kinase complex. (2001) (12)
Regulatory mechanisms involved in the control of HIV-1 gene expression (1994) (11)
Localization of the transcription factor SP1 gene to human chromosome 12q12-->q13.2. (1993) (9)
S-100 protein: a marker for melanocytic tumors. (1983) (9)
Erratum: Identification of NF-κB-regulated genes induced by TNFα utilizing expression profiling and RNA interference (Oncogene (2003) 22 (2054-2064) doi:10.1038/sj.onc.1206262) (2004) (9)
Adenovirus transcriptional regulatory regions are conserved in mammalian cells and Saccharomyces cerevisiae (1988) (9)
The human T-cell leukemia virus type-1 Tax protein regulates the activity of the IkappaB kinase complex. (1999) (9)
Abstract 942: The personalized vaccine, NEO-PV-01 with anti-PD1, induces neoantigen-specific de novo immune responses in patients with advanced metastatic melanoma: Association with clinical outcomes (2019) (8)
I-kappa B kinase beta is critical for B cell proliferation and antibody response. (2002) (8)
Regulates Estrogen-induced Cell Cycle Progression by Modulating E 2 F 1 Expression * (2006) (7)
Abstract CT125: A personal neoantigen vaccine, NEO-PV-01, with anti-PD1 induces broadde novoanti-tumor immunity in patients with metastatic melanoma, NSCLC, and bladder cancer (2018) (6)
Assignment of the gene for cyclic AMP-response element binding protein 2 (CREB2) to human chromosome 2q24.1-q32. (1991) (6)
Human immunodeficiency virus type 1 and 2 Tat proteins specifically interact with RNA polymerase II ( transcription factors / gene expression ) (2005) (5)
IkB Kinase a (IKKa) Regulation of IKKb Kinase Activity (2000) (5)
Preparative scale culture of Escherichia coli cells expressing the human immunodeficiency virus type 1 Tat protein. (1994) (4)
An open-label, phase 1b study of NEO-PV-01 with pembrolizumab plus chemotherapy in patients with advanced or metastatic nonsquamous non-small cell lung cancer. (2018) (4)
Role of IKK g /NEMO in Assembly of the I k B Kinase Complex* (2001) (3)
A role for extracellular matrix binding receptors in regulating hematopoietic growth factor signaling (2003) (3)
Small Molecule Therapeutics A Novel CDK 9 Inhibitor Shows Potent Antitumor Ef fi cacy in Preclinical Hematologic Tumor Models (2014) (3)
Systems Biology in Drug Discovery: Using Predictive Biomedicine to Guide Development Choices for Novel Agents in Cancer (2010) (3)
Purification and Functional Characterization of Wild-Type and Mutant HIV-1 and HIV-2 Tat Proteins Expressed inEscherichia coli (1996) (2)
DNA-Dependent Protein Kinase Phosphorylation of I k B a and I k B b Regulates NFk B DNA Binding Properties (1998) (2)
Abstract 5006: Comprehensive gene expression analysis of the tumor microenvironment in patients with advanced cancer treated with a personalized neoantigen vaccine, NEO-PV-01, in combination with anti-PD1 (2019) (1)
1207TiPAn open-label, Phase IB study of NEO-PV-01 + Adjuvant with Nivolumab in Patients with Melanoma, Non-Small Cell Lung Carcinoma, or Transitional Cell Carcinoma of the Bladder (2017) (1)
An open-label, phase Ib study of NEO-PV-01 + adjuvant with nivolumab in patients with melanoma, non-small cell lung carcinoma, or transitional cell carcinoma of the bladder. (2017) (1)
Tools to Interfere with NF-κB Activation (2003) (1)
153 NEO-PTC-01 (BNT-221), an autologous neoantigen-specific T-cell product for adoptive cell therapy of metastatic melanoma (2020) (0)
Adenovirus early region 1Aprotein activates transcription ofa nonviral geneintroduced intomammalian cells byinfection (1984) (0)
The Tax transactivation protein of human T-cell leukemia virus type I colocalizes with NF-κB proteins in nuclear bodies (2007) (0)
Differential RoleofLongTerminal RepeatControl Elements fortheRegulation ofBasal andTat-Mediated Transcription of theHumanImmunodeficiency Virus inStimulated and Unstimulated Primary HumanMacrophages (1994) (0)
PHOSPHORYLATION OF THE HTLV-I TAX PROTEIN ON ADJACENT SERINE RESIDUES IS CRITICAL FOR TAX ACTIVITY. (1999) (0)
Regulation of IKK α (IKK α (2014) (0)
L3.3 Role of Biomarkers in the Development of Targeted Cancer Therapeutics (2012) (0)
Chronic myelogenous leukemia: a paradigm for novel molecular and immunologic approaches for cancer treatment (2000) (0)
Heat Shock Protein 27 Association with the I (cid:1)(cid:2) Kinase Complex Regulates Tumor Necrosis Factor (cid:3) -induced NF- (cid:1) B Activation* (2003) (0)
Role of the TAR Element in Regulating HIV Gene Expression (1991) (0)
Identification and Validation of Genes Involved in the Pathogenesis of Colorectal Cancer Using cDNA Microarrays and RNA Interference 1 (2003) (0)
Abstract S03-02: Sequence-based prediction of SARS-CoV-2 vaccine targets using a mass spectrometry-based bioinformatics predictor identifies immunogenic T-cell epitopes (2020) (0)
Abstract LB-147: Comprehensive immune and molecular analysis of two metastatic melanoma patients treated with a personal neoantigen vaccine, NEO-PV-01, in combination with anti-PD1: A case study (2018) (0)
Deletion of the bulge region or substitution for a single U residue at + 23 in the bulge region also severely decreases tat activation ( Berkhout and Jeang 1988 (2007) (0)
Regulating Murine T Cell Function Have Distinct Roles in β and α B Kinases κ (2002) (0)
Abstract PL07-02: Rational cancer drug development for targeted drugs. (2011) (0)
RoleofFlanking E BoxMotifs inHumanImmunodeficiency Virus Type1TATA Element Function (1994) (0)
Purification and functional characterization of wild-type and mutant HIV-1 and HIV-2 Tat proteins expressed in Escherichia coli. (1996) (0)
Abstract 580: Detailed analysis of immune responses induced against patient-specific neoantigens using theex-vivoinduction protocol, NEO-STIM™ (2019) (0)
Regulation o f N F - k B by the HTLV-1 Tax Protein (2016) (0)
Subject Index Vol. 64, 1993 (1993) (0)
Edinburgh Research Explorer Differential role of long terminal repeat control elements for the regulation of basal and Tat-mediated transcription of the human immunodeficiency virus in stimulated and unstimulated primary human macrophages (0)
Abstract PO-015: Systematic discovery of KRAS neoantigens (2020) (0)
Heat Shock Protein 27 Association with the I Kinase Complex Regulates Tumor Necrosis Factor -induced NF- B Activation* (2003) (0)
364 A personal neoantigen vaccine NEO-PV-01 in combination with chemotherapy and pembrolizumab induces broad de novo immune responses in first line, non-squamous NSCLC (2020) (0)
Identification of aberrantly expressed proteins in colorectal carcinoma (2002) (0)
Novel HIV-1 Therapeutic Targets: (2021) (0)
Abstract B23: Enhanced HLA-II epitope prediction for immunotherapy with novel proteomics and genomics approaches (2020) (0)
Regulation ofHumanImmunodeficiency VirusEnhancer Function byPRDII-BF1 andc-rel GeneProducts CHRISTIANMUCHARDT,JACOB-S.SEELER,AJAYNIRULA,DIXIE-LEESHURLAND, (1992) (0)
Activation of gene expression by the human T-cell leukemia virus transactivator tax occurs in unique nuclear structures (1999) (0)
Multiple Transcriptional Regulatory DomainsintheHuman Immunodeficiency VirusType1LongTerminal Repeat Are Involved inBasalandElA/ElB-Induced Promoter Activity (1989) (0)

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