Richard Green
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Neuropharmacologist
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Richard Green biology Degrees
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Richard Green 's Degrees
- PhD Pharmacology Stanford University
Why Is Richard Green Influential?
(Suggest an Edit or Addition)According to Wikipedia, Professor Richard Green was a British neuropharmacologist. Green obtained his PhD in 1969 under the supervision of Gerald Curzon, and then spent two years at the National Institute of Mental Health in Washington, D.C.
Richard Green 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) (2003) (1178)
- Rapid method for the determination of 5‐hydroxytryptamine and 5‐hydroxyindoleacetic acid in small regions of rat brain (1970) (896)
- A behavioural and biochemical study in mice and rats of putative selective agonists and antagonists for 5‐HT1 and 5‐HT2 receptors (1985) (370)
- The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(DI-n-propylamino)tetralin (8-OH-DPAT) A model of presynaptic 5-HT1 function (1985) (253)
- The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (`ecstasy') (1998) (247)
- Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or “Ecstasy”) (1995) (241)
- The pharmacology of the acute hyperthermic response that follows administration of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) to rats (2002) (228)
- Ethyl β-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats (1981) (213)
- GABA potentiation: a logical pharmacological approach for the treatment of acute ischaemic stroke (2000) (193)
- Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptamine (1976) (188)
- In vivo evidence for free radical involvement in the degeneration of rat brain 5‐HT following administration of MDMA (‘ecstasy’) and p‐chloroamphetamine but not the degeneration following fenfluramine (1997) (183)
- A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response. (2004) (181)
- The hyperthermic and neurotoxic effects of ‘Ecstasy’ (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype (1995) (173)
- 3,4-Methylenedioxymethamphetamine induces monoamine release, but not toxicity, when administered centrally at a concentration occurring following a peripherally injected neurotoxic dose (2001) (164)
- 5‐HT2 receptor characteristics in frontal cortex and 5‐HT2 receptor‐mediated head‐twitch behaviour following antidepressant treatment to mice (1984) (163)
- Inhibition of 5-hydroxytryptamine-mediated behaviour by the putative 5-HT2 antagonist pirenperone (1983) (155)
- Animal models of acute ischaemic stroke: can they predict clinically successful neuroprotective drugs? (1995) (152)
- EFFECTS OF MONOAMINE OXIDASE INHIBITION BY CLORGYLINE, DEPRENIL OR TRANYLCYPROMINE ON 5‐HYDROXYTRYPTAMINE CONCENTRATIONS IN RAT BRAIN AND HYPERACTIVITY FOLLOWING SUBSEQUENT TRYPTOPHAN ADMINISTRATION (1975) (152)
- EVIDENCE FOR DOPAMINE DEAMINATION BY BOTH TYPE A AND TYPE B MONOAMINE OXIDASE IN RAT BRAIN in vivo AND FOR THE DEGREE OF INHIBITION OF ENZYME NECESSARY FOR INCREASED FUNCTIONAL ACTIVITY OF DOPAMINE AND 5‐HYDROXYTRYPTAMINE (1977) (152)
- THE EFFECTS OF PUTATIVE 5‐HYDROXYTRYPTAMINE ANTAGONISTS ON THE BEHAVIOUR PRODUCED BY ADMINISTRATION OF TRANYLCYPROMINE AND L‐TRYPTOPHAN OR TRANYLCYPROMINE AND L‐DOPA TO RATS (1978) (149)
- Effect of NXY‐059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window (2002) (149)
- A study of the neurotoxic effect of MDMA (‘ecstasy’) on 5‐HT neurones in the brains of mothers and neonates following administration of the drug during pregnancy (1997) (149)
- ELECTROCONVULSIVE SHOCK INCREASES THE BEHAVIOURAL RESPONSES OF RATS TO BRAIN 5‐HYDROXYTRYPTAMINE ACCUMULATION AND CENTRAL NERVOUS SYSTEM STIMULANT DRUGS (1976) (148)
- Acute and long-term effects of MDMA on cerebral dopamine biochemistry and function (2004) (147)
- Administration of thyrotropin releasing hormone (TRH) to rats releases dopamine in n. accumbens but not n. caudatus (1979) (146)
- MECHANISM OF THE ANTIDEPRESSANT ACTION OF ELECTROCONVULSIVE THERAPY (1978) (146)
- 5‐HT loss in rat brain following 3, 4‐methylenedioxymethamphetamine (MDMA), p‐chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine (1993) (145)
- The effects of benzodiazepines and serotonergic manipulations on punished responding (1979) (141)
- Decrease of 5-Hydroxytryptamine in the Brain provoked by Hydrocortisone and its Prevention by Allopurinol (1968) (138)
- Brain noradrenaline depletion prevents ECS-induced enhancement of serotonin-and dopamine-mediated behaviour (1980) (138)
- Presynaptic serotonin receptor-mediated response in mice attenuated by antidepressant drugs and electroconvulsive shock (1985) (129)
- A study of the mechanisms involved in the neurotoxic action of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) on dopamine neurones in mouse brain (2001) (127)
- (−)-Propranolol inhibits the behavioural responses of rats to increased 5-hydroxytryptamine in the central nervous system (1976) (123)
- Quipazine: Its effects on rat brain 5-hydroxytryptamine metabolism, monoamine oxidase activity and behaviour (1976) (118)
- The role of brain dopamine in the hyperactivity syndrome produced by increased 5-hydroxytryptamine synthesis in rats. (1974) (115)
- THE ROLE OF BRAIN 5‐HYDROXYTRYPTAMINE IN THE HYPERACTIVITY PRODUCED IN RATS BY LITHIUM AND MONOAMINE OXIDASE INHIBITION (1974) (115)
- 5-HT-mediated behaviour Animal studies (1984) (115)
- Neuroprotective activity of chlormethiazole following transient forebrain ischaemia in the gerbil (1991) (113)
- The behavioural effects of RU 24969, a suggested 5-HT1 receptor agonist in rodents and the effect on the behaviour of treatment with antidepressants (1984) (112)
- Neuropharmacology of serotonin (1985) (111)
- The mechanisms involved in the long‐lasting neuroprotective effect of fluoxetine against MDMA (‘ecstasy’)‐induced degeneration of 5‐HT nerve endings in rat brain (2001) (110)
- Effect of GBR 12909 and fluoxetine on the acute and long term changes induced by MDMA (‘ecstasy’) on the 5-HT and dopamine concentrations in mouse brain (2001) (108)
- The spin trap reagent alpha-phenyl-N-tert-butyl nitrone prevents 'ecstasy'-induced neurodegeneration of 5-hydroxytryptamine neurones. (1995) (106)
- The effects of iron deficiency on brain biogenic monoamine biochemistry and function in rats (1980) (102)
- Repeated electroconvulsive shock attenuates clonidine-induced hypoactivity in rodents. (1981) (102)
- Effects of immobilization on rat liver tryptophan pyrrolase and brain 5‐hydroxytryptamine metabolism (1969) (101)
- A BEHAVIOURAL AND BIOCHEMICAL STUDY IN RATS OF 5‐HYDROXYTRYPTAMINE RECEPTOR AGONISTS AND ANTAGONISTS, WITH OBSERVATIONS ON STRUCTURE‐ACTIVITY REQUIREMENTS FOR THE AGONISTS (1981) (92)
- TRH potentiates behavioural changes following increased brain 5-hydroxytryptamine accumulation in rats (1974) (89)
- A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066 (1999) (89)
- Role of hyperthermia in the protective action of clomethiazole against MDMA (‘ecstasy’)‐induced neurodegeneration, comparison with the novel NMDA channel blocker AR‐R15896AR (1998) (88)
- Atenolol reduces plasma melatonin concentration in man. (1983) (87)
- Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA (‘Ecstasy’) to rats (1994) (86)
- Studies on the role of dopamine in the degeneration of 5‐HT nerve endings in the brain of Dark Agouti rats following 3,4‐methylenedioxymethamphetamine (MDMA or ‘ecstasy’) administration (1999) (86)
- ALTERATIONS IN GABA METABOLISM AND MET‐ENKEPHALIN CONTENT IN RAT BRAIN FOLLOWING REPEATED ELECTROCONVULSIVE SHOCKS (1978) (85)
- Studies, using in vivo microdialysis, on the effect of the dopamine uptake inhibitor GBR 12909 on 3,4‐methylenedioxymethamphetamine (‘ecstasy’)‐induced dopamine release and free radical formation in the mouse striatum (2002) (83)
- Desipramine treatment in normal subjects. Effects on neuroendocrine responses to tryptophan and on platelet serotonin (5-HT)-related receptors. (1986) (82)
- The effects of chlormethiazole and nimodipine on cortical infarct area after focal cerebral ischaemia in the rat (1993) (82)
- Behavioural and neurochemical comparison of chronic intermittent cathinone, mephedrone and MDMA administration to the rat (2013) (81)
- Effect of hydrocortisone on rat brain 5-hydroxytryptamine (1968) (81)
- 3,4‐Methylenedioxymethamphetamine increases interleukin‐1β levels and activates microglia in rat brain: studies on the relationship with acute hyperthermia and 5‐HT depletion (2004) (80)
- β‐ADRENOCEPTOR ANTAGONISTS INHIBIT THE BEHAVIOURAL RESPONSES OF RATS TO INCREASED BRAIN 5‐HYDROXYTRYPTAMINE (1978) (79)
- Identification and quantitation of a new indolealkylamine in rat hypothalamus. (1973) (79)
- The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism. (1970) (79)
- The pharmacology of the behavioral and hypothermic responses of rats to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) (2004) (78)
- Increased 5‐HT2 receptor number in brain as a probable explanation for the enhanced 5‐hydroxytryptamine‐mediated behaviour following repeated electroconvulsive shock administration to rats (1983) (77)
- Dopamine and norepinephrine in noradrenergic axons: a study in vivo of their precursor product relationship by mass fragmentography and radiochemistry. (1972) (77)
- The neurotoxic effects of methamphetamine on 5-hydroxytryptamine and dopamine in brain: Evidence for the protective effect of chlormethiazole (1992) (76)
- Elevation of Ambient Room Temperature has Differential Effects on MDMA-Induced 5-HT and Dopamine Release in Striatum and Nucleus Accumbens of Rats (2005) (76)
- Iron deficiency and neurotransmitter synthesis and function (1978) (75)
- The cholinergic pharmacology of tetrahydroaminoacridine in vivo and in vitro (1989) (75)
- A comparative study on the acute and long‐term effects of MDMA and 3,4‐dihydroxymethamphetamine (HHMA) on brain monoamine levels after i.p. or striatal administration in mice (2005) (74)
- Antidepressant treatments: effects in rodents on dose‐response curves of 5‐hydroxytryptamine‐ and dopamine‐mediated behaviours and 5‐HT2 receptor number in frontal cortex (1983) (74)
- Studies on the post-ictal rise in seizure threshold. (1981) (72)
- Studies on the effect of MDMA (‘ecstasy’) on the body temperature of rats housed at different ambient room temperatures (2005) (71)
- The neuroprotective effect of chlormethiazole on ischaemic neuronal damage following permanent middle cerebral artery ischaemia in the rat. (1995) (69)
- Regional and subcellular changes in the concentration of 5‐hydroxytryptamine and 5‐hydroxyindoleacetic acid in the rat brain caused by hydrocortisone, DL‐α‐methyltryptophan l‐kynurenine and immobilization (1971) (69)
- Effect of Repeated (‘Binge’) Dosing of MDMA to Rats Housed at Normal and High Temperature on Neurotoxicdamage to Cerebral 5-Ht and Dopamine Neurones (2004) (69)
- The modulation by chlormethiazole of the GABAA‐receptor complex in rat brain (1989) (68)
- The pharmacokinetic profile of lithium in rat and mouse; An important factor in psychopharmacological investigation of the drug (1986) (67)
- Striatal dopamine release in vivo following neurotoxic doses of methamphetamine and effect of the neuroprotective drugs, chlormethiazole and dizocilpine (1993) (66)
- MDMA‐induced neurotoxicity: long‐term effects on 5‐HT biosynthesis and the influence of ambient temperature (2006) (65)
- GABAB‐receptor mediated inhibition of potassium‐evoked release of endogenous 5‐hydroxytryptamine from mouse frontal cortex (1987) (65)
- Increased GABAB receptor function in mouse frontal cortex after repeated administration of antidepressant drugs or electroconvulsive shocks (1987) (65)
- MDMA: On the translation from rodent to human dosing (2009) (63)
- The effect of chlormethiazole on neuronal damage in a model of transient focal ischaemia (1995) (63)
- Hypothermia induced by baclofen, a possible index of GABAB receptor function in mice, is enhanced by antidepressant drugs and ECS (1987) (63)
- On the measurement in rats of the convulsant effect of drugs and the changes which follow electroconvulsive shock (1980) (62)
- Down-regulation of β-adrenoceptors in rat cortex by repeated administration of desipramine, electroconvulsive shock and clenbuterol requires 5-HT neurones but not 5-HT (1985) (62)
- Neuroprotective agents and cerebral ischaemia (1997) (62)
- A study of the mechanism of MDMA (‘Ecstasy’)‐induced neurotoxicity of 5‐HT neurones using chlormethiazole, dizocilpine and other protective compounds (1994) (61)
- The effect of diphenylhydantoin on brain 5-hydroxytryptamine metabolism and function (1975) (61)
- Ecstasy and neurodegeneration (1996) (61)
- The effects of acute and repeated administration of various antidepressant drugs on clonidine-induced hypoactivity in mice and rats (1983) (61)
- Effect of ambient temperature and a prior neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA) on the hyperthermic response of rats to a single or repeated (‘binge’ ingestion) low dose of MDMA (2004) (60)
- Metabolism of an oral tryptophan load. I: Effects of dose and pretreatment with tryptophan. (1980) (59)
- β‐ADRENOCEPTOR AGONISTS ENHANCE 5‐HYDROXYTRYPTAMINE‐MEDIATED BEHAVIOURAL RESPONSES (1982) (59)
- Effect of chronic treatment with 5‐HT1 agonist (8‐OH‐DPAT and RU 24969) and antagonist (isapirone) drugs on the behavioural responses of mice to 5‐HT1 and 5‐HT2 agonists (1986) (59)
- Repeated electroconvulsive shock increases the behavioural responses of rats to injection of both dopamine and dibutyryl cyclic amp into the nucleus accumbens (1978) (58)
- Attenuation by chlormethiazole administration of the rise in extracellular amino acids following focal ischaemia in the cerebral cortex of the rat (1994) (58)
- The mechanism of adenosine diphosphate induced platelet aggregation: binding to platelet receptors and inhibition of binding and aggregation by prostaglandin E1 (1972) (56)
- Tranylcypromine (‘Parnate’) overdose: measurement of tranylcypromine concentrations and MAO inhibitory activity and identification of amphetamines in plasma (1979) (56)
- The enhancement by lithium of the 5-HT1A mediated serotonin syndrome produced by 8-OH-DPAT in the rat: evidence for a post-synaptic mechanism (2004) (55)
- EVIDENCE CONCERNING THE INVOLVEMENT OF 5‐HYDROXYTRYPTAMINE IN THE LOCOMOTOR ACTIVITY PRODUCED BY AMPHETAMINE OR TRANYLCYPROMINE PLUS l‐DOPA (1976) (54)
- Biogenic monoamine metabolism and functional activity in iron-deficient rats: behavioural correlates. (2008) (53)
- Comparison of the neuroprotective effect of clomethiazole, AR-R15896AR and NXY-059 in a primate model of stroke using histological and behavioural measures (2003) (52)
- Plasma melatonin during desmethylimipramine treatment: evidence for changes in noradrenergic transmission. (1985) (51)
- Behavioural effects of central and peripheral injection of various analogues and metabolites of Thyrotropin Releasing Hormone (TRH) (1981) (50)
- The protective action of chlormethiazole against ischaemia‐induced neurodegeneration in gerbils when infused at doses having little sedative or anticonvulsant activity (1995) (50)
- On the anxiogenic and anxiolytic nature of long-term cerebral 5-HT depletion following MDMA (2002) (50)
- REGIONAL RAT BRAIN BENZODIAZEPINE RECEPTOR NUMBER AND γ‐AMINOBUTYRIC ACID CONCENTRATION FOLLOWING A CONVULSION (1982) (50)
- LIVER AND BRAIN TRYPTOPHAN METABOLISM FOLLOWING HYDROCORTISONE ADMINISTRATION TO RATS AND GERBILS (1975) (49)
- Attenuation by electroconvulsive shock and antidepressant drugs of the 5-HT1A receptor-mediated hypothermia and serotonin syndrome produced by 8-OH-DPAT in the rat (2004) (48)
- Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions—III the effects of monoamine antagonists and synthesis inhibitors on the ability of electroconvulsive shock to enhance responses (1980) (45)
- Differential effect of dietary selenium on the long-term neurotoxicity induced by MDMA in mice and rats (2003) (45)
- Studies on the mechanisms by which clenbuterol, a β-adrenoceptor agonist, enhances 5-HT-mediated behaviour and increases metabolism of 5-HT in the brain of the rat (1983) (43)
- Psychopharmacology of Repeated Seizures: Possible Relevance to the Mechanism of Action of Electroconvulsive Therapy (1987) (41)
- The effect of chronic antidepressant administration on β‐adrenoceptor function of the rat pineal (1983) (40)
- Current preclinical studies on neuroinflammation and changes in blood–brain barrier integrity by MDMA and methamphetamine (2014) (39)
- The effect of repeated electroconvulsive shock on GABA synthesis and release in regions of rat brain (1987) (39)
- Factors influencing effect of hydrocortisone on rat brain tryptophan metabolism (1975) (39)
- Some anticonvulsant drugs alter monoamine‐mediated behaviour in mice in ways similar to electroconvulsive shock; implications for antidepressant therapy (1985) (38)
- Evolving concepts on the interactions between antidepressant treatments and monoamine neurotransmitters (1987) (37)
- On the regulation of ischaemia‐induced glutamate efflux from rat cortex by GABA; in vitro studies with GABA, clomethiazole and pentobarbitone (2000) (37)
- 5-Hydroxytryptamine and Other Indoles in the Central Nervous System (1975) (37)
- Studies on the neuroprotective effect of pentobarbitone on MDMA-induced neurodegeneration (1999) (37)
- The mechanism of tetrahydroaminoacridine‐evoked release of endogenous 5‐hydroxytryptamine and dopamine from rat brain tissue prisms (1989) (36)
- Effect of Electroconvulsive Shock on the Uptake and Release of Noradrenaline and 5‐Hydroxytryptamine in Rat Brain Slices (1983) (36)
- Contribution of serotonin and dopamine to changes in core body temperature and locomotor activity in rats following repeated administration of mephedrone (2016) (35)
- The contrasting actions of TRH and cycloheximide in altering the effects of centrally acting drugs: Evidence for the non-involvement of dopamine sensitive adenylate cyclase (1976) (35)
- The nNOS inhibitor, AR‐R17477AR, prevents the loss of NF68 immunoreactivity induced by methamphetamine in the mouse striatum (2003) (34)
- Further observations on the effect of repeated electroconvulsive shock on the behavioural resposes of rats produced by increases in the functional activity of brain 5-hydroxytryptamine and dopamine (1977) (34)
- The administration of baclofen to mice increases 5-HT2-mediated head-twitch behaviour and 5-HT2 receptor number in frontal cortex (1985) (34)
- Inhibition of the rate of GABA synthesis in regions of rat brain following a convulsion (1987) (33)
- Animal Models of Serotonin Behavior (1990) (33)
- The binding of [3H]thienyl cyclohexylpiperidine ([3H]TCP) to the NDDA-phencyclidine receptor complex (1989) (33)
- A simple intravenous infusion method in rodents for determining the potency of anticonvulsants acting through GABAergic mechanisms (1989) (31)
- The role of 5-HT in the impairment of thermoregulation observed in rats administered MDMA (‘ecstasy’) when housed at high ambient temperature (2005) (31)
- The concentration of 5-methoxytryptamine in rat brain and its effects on behaviour following its peripheral injection (1975) (31)
- Neurotransmitters and Second Messengers in Aging and Alzheimer's Disease (1993) (30)
- The spin trap reagent PBN attenuates degeneration of 5-HT neurones in rat brain induced by p-chloroamphetamine but not fenfluramine (1996) (30)
- Effects of hydrocortisone and immobilization on tryptophan metabolism in brain and liver of rats of different ages. (1975) (30)
- Lithium decreases 5-HT1A and 5-HT2 receptor and α2-adrenoreceptor mediated function in mice (2004) (30)
- Comparison of donepezil-, tacrine-, rivastigmine-and metrifonateinduced central and peripheral cholinergically mediated responses in the rat (2000) (30)
- A Behavioural and Neurochemical Study in Rats of the Pharmacology of Loreclezole, a Novel Allosteric Modulator of the GABAA Receptor (1996) (29)
- Effects of the putative antagonists phaclofen and δ‐aminovaleric acid on GABAB receptor biochemistry (1989) (29)
- The acute effect in rats of 3,4-methylenedioxyethamphetamine (MDEA, "eve") on body temperature and long term degeneration of 5-HT neurones in brain: a comparison with MDMA ("ecstasy"). (1999) (29)
- Techniques for examining neuroprotective drugs in vivo. (1997) (28)
- Oral contraceptives, depression, and aminoacid metabolism. (1970) (28)
- Studies on the locomotor activity produced by injection of dibutyryl cyclic 3 5 AMP into the nucleus accumbens of rats (1978) (28)
- Hyperthermic and neurotoxic effect of 3,4-methylenedioxymethamphetamine (MDMA) in guinea pigs (2004) (28)
- The effects of GABAB receptor agonists and antagonists on potassium-stimulated [Ca2+]i in rat brain synaptosomes (1989) (26)
- Clomethiazole (Zendra) in acute ischemic stroke: basic pharmacology and biochemistry and clinical efficacy. (1998) (26)
- The differential effects of felodipine and nitrendipine on cerebral dihydropyridine binding ex vivo and the ethanol withdrawal syndrome in mice (1994) (26)
- Interactions of β-adrenoceptor agonists and antagonists with the 5-hydroxytryptamine2 (5-HT2) receptor (1983) (26)
- TRYPTOPHAN METABOLISM IN THE ISOLATED PERFUSED LIVER OF THE RAT: EFFECTS OF TRYPTOPHAN CONCENTRATION, HYDROCORTISONE AND ALLOPURINOL ON TRYPTOPHAN PYRROLASE ACTIVITY AND KYNURENINE FORMATION (1976) (26)
- The neuroprotective actions of chlormethiazole (1994) (25)
- Mechanisms by which human blood platelets accumulate glycine, gaba and amino acid precursors of putative neurotransmitters (1972) (25)
- 3,4-Methylenedioxymethamphetamine increases pro-interleukin-1β production and caspase-1 protease activity in frontal cortex, but not in hypothalamus, of Dark Agouti rats: Role of interleukin-1β in neurotoxicity (2005) (25)
- REPEATED EXPOSURE OF RATS TO THE CONVULSANT AGENT FLUROTHYL ENHANCES 5‐HYDROXYTRYPTAMINE‐ AND DOPAMINE‐MEDIATED BEHAVIOURAL RESPONSES (1978) (24)
- Inhibition of GABA release from slices prepared from several brain regions of rats at various times following a convulsion (1987) (24)
- The use of the Chandler loop to examine the interaction potential of NXY‐059 on the thrombolytic properties of rtPA on human thrombi in vitro (2008) (24)
- Acetylcholinesterase Activity in Regions of the Rat Brain Following a Convulsion (1986) (23)
- The immediate consequences of middle cerebral artery occlusion on GABA synthesis in mouse cortex and cerebellum (1992) (23)
- Gaddum and LSD: the birth and growth of experimental and clinical neuropharmacology research on 5‐HT in the UK (2008) (23)
- Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions—II the effects of anaesthesia and current conditions on the appearance of enhanced responses following electroconvulsive shock (1980) (22)
- The effects of Ca2+ antagonists and hydralazine on central 5‐hydroxytryptamine biochemistry and function in rats and mice (1990) (22)
- The effect of oedema and tissue swelling on the measurement of neuroprotection; a study using chlormethiazole and permanent middle cerebral artery occlusion in rats. (1996) (22)
- Reversal by tetrahydroaminoacridine of scopolamine-induced memory and performance deficits in rats (2006) (22)
- Spermidine enhancement of [3H]MK-801 binding to the NMDA receptor complex in human cortical membranes. (1990) (22)
- The effects of a 5-HT1 receptor ligand isapirone (TVX Q 7821) on 5-HT synthesis and the behavioural effects of 5-HT agonists in mice and rats (2004) (22)
- Protection against 3,4‐methylenedioxymethamphetamine‐induced neurodegeneration produced by glutathione depletion in rats is mediated by attenuation of hyperthermia (2002) (21)
- Regional GABA concentration and [3H]-diazepam binding in rat brain following repeated electroconvulsive shock (2005) (21)
- Brain monoamines and the high pressure neurological syndrome (1980) (21)
- The effects of the gaba-mimetic drugs, progabide and baclofen, on the biochemistry and function of 5-hydroxytryptamine and noradrenaline (1986) (21)
- Metabolism of an oral tryptophan load by women and evidence against the induction of tryptophan pyrrolase by oral contraceptives. (1978) (20)
- Repeated administration of subconvulsant doses of GABA antagonist drugs (2004) (20)
- Effects of Intracranial Dopamine Perfusion: Behavioural Arousal and Reversal of Cerebral Arterial Spasm following Surgery for Clipping of Ruptured Cerebral Aneurysms (1977) (20)
- Further evidence for a relationship between changes in GABA concentration in rat brain and enhanced monoamine-mediated behavioural responses following repeated electroconvulsive shock (1982) (20)
- MDMA: fact and fallacy, and the need to increase knowledge in both the scientific and popular press (2004) (19)
- Measurements of tacrine and monoamines in brain by in vivo microdialysis argue against release of monoamines by tacrine at therapeutic doses (1991) (19)
- Effect of 5-HT depletion by MDMA on hyperthermia and Arc mRNA induction in rat brain (2004) (19)
- The effects of single and repeated electroconvulsive shock administration on the release of 5‐hydroxytryptamine and noradrenaline from cortical slices of rat brain (1987) (19)
- Decrease in levels of thyrotrophin-releasing hormone (TRH) in the N. accumbens and lumbar spinal cord following repeated electroconvulsive shock (1984) (19)
- A Comparison of [3H]MK‐801 and N‐[1‐(2‐Thienyl)cyclohexyl]‐3,4‐[3H]Piperidine Binding to the N‐Methyl‐D‐Aspartate Receptor Complex in Human Brain (1991) (18)
- Opiate agonists and antagonists modulate taste perception in opiate-maintained and recently detoxified subjects (2013) (18)
- Can the human blood platelet be used as a model for the cholinergic nerve ending (1972) (18)
- Electroconvulsive shock reduces the cataleptogenic effect of both haloperidol and arecoline in rats (1979) (17)
- Pharmacology should be at the centre of all preclinical and clinical studies on new psychoactive substances (recreational drugs) (2014) (17)
- The acute and long-term neurotoxic effects of MDMA on marble burying behaviour in mice (2006) (17)
- Cathinone increases body temperature, enhances locomotor activity, and induces striatal c-fos expression in the Siberian hamster (2014) (16)
- On the convulsant action of Ro 5-4864 and the existence of a micromolar benzodiazepine binding site in rat brain (2004) (15)
- Single and repeated administration of neuroleptic drugs to rats: Effects on striatal dopamine-sensitive adenylate cyclase and locomotor activity produced by tranylcypromine and L-tryptophan or L-dopa (1976) (15)
- Enhanced 5-hydroxytryptamine-mediated behavioural responses in rats following repeated electroconvulsive shock: Relevance to the mechanism of the antidepressive effect of electroconvulsive therapy (1979) (14)
- Using Ro 15-1788 to investigate the benzodiazepine receptor in vivo: Studies on the anticonvulsant and sedative effect of melatonin and the convulsant effect of the benzodiazepine Ro 05-3663 (2004) (14)
- Lithium decreases 5-HT1A and 5-HT2 receptor and alpha 2-adrenoceptor mediated function in mice. (1986) (14)
- Attenuation by chlormethiazole of oedema following focal ischaemia in the cerebral cortex of the rat (1994) (13)
- Changes in the behavioural response to a TRH analogue following chronic amitriptyline treatment and repeated electroconvulsive shock in the rat (1986) (13)
- REPEATED CHLORPROMAZINE ADMINISTRATION INCREASES A BEHAVIOURAL RESPONSE OF RATS TO 5‐HYDROXYTRYPTAMINE RECEPTOR STIMULATION (1977) (13)
- Effect of chlormethiazole, dizocilpine and pentobarbital on harmaline-induced increase of cerebellar cyclic GMP and tremor (2005) (13)
- Elevation of brain GABA concentrations with amino-oxyacetic acid; effect on the hyperactivity syndrome produced by increased 5-hydroxytryptamine synthesis in rats (2005) (12)
- The effects of electroconvulsive therapy and antidepressant drugs on monoamine receptors in rodent brain--similarities and differences. (1986) (12)
- Protein Synthesis by Human Blood Platelets after Accumulation of Leucine and Arginine (1972) (12)
- Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions—I the effects of single and repeated bicuculline-induced seizures (1980) (11)
- Rat liver tryptophan pyrrolase activity and brain 5-hydroxytryptamine. (1969) (11)
- Inhibition of apomorphine-, bromocriptine- and lergotrile-induced circling behaviour in rats by subsequent haloperidol administration (1980) (11)
- An investigation of the possible interaction of clomethiazole with glutamate and ion channel sites as an explanation of its neuroprotective activity. (1998) (11)
- Acetylcholinesterase activity rises in rat cerebrospinal fluid post‐ictally; effect of a substantia nigra lesion on this rise and on seizure threshold (1987) (11)
- Proceedings: The role of brain dopamine in the hyperactivity syndrome produced in rats after administration of L-tryptophan and a monoamine oxidase inhibitor. (1974) (10)
- The β 2-adrenoceptor agonists clenbuterol and salbutamol enhance the hypothermic action of 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) in mice by a central mechanism (1986) (10)
- The metabolism of clomethiazole in gerbils and the neuroprotective and sedative activity of the metabolites (2000) (10)
- Metabolism of an oral tryptophan load. II: Effect of pretreatment with the putative tryptophan pyrrolase inhibitors nicotinamide or allopurinol. (1980) (10)
- Metabolism of an oral tryptophan load III: effect of a pyridoxine supplement. (1980) (9)
- Some histological and metabolic properties of an isolated perfused rat brain preparation with special reference to monoamine metabolism (1976) (9)
- The pharmacokinetics of L-tryptophan following its intravenous and oral administration. (1985) (9)
- Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats (2016) (8)
- Responses of developing rats to l-tryptophan plus an MAOI—I. Monitoring changes in behaviour, brain 5-HT and tryptophan (1980) (8)
- Action of chlormethiazole in a model of ethanol withdrawal (2005) (8)
- The effects of dietary tryptophan and its peripheral metabolism on brain-5-hydroxytryptamine synthesis and function. (1978) (8)
- Processes regulating the functional activity of brain 5-hydroxytryptamine: results of animal experimentation and their relevance to the understanding and treatment of depression. (1978) (8)
- BRAIN AND SERUM CALCIUM CONCENTRATIONS FOLLOWING ELECTROCONVULSIVE SHOCK OR BICUCULLINE‐INDUCED CONVULSIONS IN RATS (1980) (7)
- Repeated electroconvulsive shock has no specific anxiolytic effect but reduces social interaction and exploration in rats (1984) (7)
- Chlormethiazole and dizocilpine block the behavioural, but not the neurotoxic effects of 5,7-dihydroxytryptamine in mice. (1994) (7)
- Analysis of pineal and brain indole alkylamines by gas chromatography-mass spectrometry. (1973) (7)
- Proceedings: The role of brain 5-hydroxytryptamine in the hyperactivity produced in rats by lithium and monoamine oxidase inhibition. (1974) (7)
- Responses of developing rats to l-tryptophan plus an MAOI—II. Effects of repeated electroconvulsive shock (1980) (6)
- Anti-depressant treatments and serotonin receptor number and function. (2009) (6)
- Studies on rat brain catecholamine synthesis and Β-adrenoceptor number following administration of electroconvulsive shock, desipramine and clenbuterol (2005) (5)
- On the protection against methamphetamine-induced neurotoxicity by benzamide, a PARP inhibitor (2002) (5)
- The effect of iron deficiency on brain monoamine metabolism and the behavioural responses to increased brain 5-hydroxytryptamine and dopamine synthesis [proceedings]. (1977) (5)
- How do we re-engage the pharmaceutical industry in research on serotonin and psychiatric disorders? (2013) (5)
- The mechanism of action of antidepressant treatments: basic aspects. (1988) (4)
- Repeated electroconvulsive shock does not increase the susceptibility of rats to a cage convulsant (Isopropylbicyclophosphate) (1980) (4)
- Pharmacological studies on serotonin-mediated behaviour. (1981) (4)
- Distribution of Neurochemical Deficits in Alzheimer’s Disease (1990) (4)
- The effect of electroconvulsive shock on learning and memory in rats (1984) (4)
- Chlormethiazole antagonises seizures induced by N-methyl-dl-aspartate without interacting with the NMDA receptor complex (2005) (3)
- Acetylcholinesterase activity in regions of rat brain following repeated administration of electroconvulsive shock (1987) (3)
- Release of dopamine in the nucleus accumbens of rats by thyrotropin releasing hormone (TRH) [proceedings]. (1978) (2)
- P.6.d.001 The effects of MDMA pre-treatment on behavioural responses to mephedrone in the rat (2012) (2)
- Relevance of the enhanced 5-hydroxytryptamine behavioural responses in rats to electroconvulsive therapy [proceedings]. (1978) (2)
- Studies on the enhancement of 5-hydroxytryptamine-mediated behaviour by chlormethiazole and phenytoin (1992) (2)
- 5-Hydroxytryptamine synthesis in the isolated perfused rat brain. (1975) (2)
- Neuroleptic drugs block both the hyperactivity and the increase in caudate nucleus cyclic AMP concentration produced by the administration of tranylcypromine and l-dopa to rats (1978) (2)
- AMINES, ANTICONVULSANTS, AND EPILEPSY (1975) (2)
- Diazepam administration to mice prevents some of the changes in monoamine-mediated behaviour produced by repeated electroconvulsive shock treatment (2004) (1)
- P.1.g.026 Contribution of 5-HT and dopamine to the physiological and behavioural effects of mephedrone following binge dosing in the rat (2014) (1)
- Proceedings: Tryptophan metabolism by the isolated perfused rat liver. (1975) (1)
- Thepharmacokinetics ofL-tryptophan following its intravenous andoral administration (1985) (1)
- Repeated administration of subconvulsant doses of GABA antagonist drugs (2004) (1)
- Monoamine metabolism in the isolated perfused rat brain. (1976) (1)
- 695 – EFFECT OF BRAIN 5-HT AGONISTS AND ANTAGONISTS ON PLATELET AGGREGATION (1977) (1)
- 5-Methoxytryptamine: stimulation of 5-HT receptors mediating the rat hyperactivity syndrome and blood platelet aggregation. (1976) (1)
- MDMA and Other “Club Drugs” (2007) (1)
- Extending the time window: Studies with NXY-059 in animal models of stroke (2001) (1)
- Theeffect ofchlormethiazole on neuronal damageina modeloftransient focal ischaemia (1995) (1)
- Use of a Behavioural Model to Study the Action of Monoamine Oxidase Inhibition in vivo (2008) (1)
- The effect of alpha- and beta-receptor blocking agents on gastric acid secretion in guinea-pigs. (1983) (1)
- Lack of long term effect of p-chlorophenylalanine on brain 5-hydroxytryptamine and electrocortical activity in conscious fetal sheep (1984) (0)
- synthesis in the isolated perfused rat brain (2006) (0)
- BEHAVIOURAL EFFECTS OF 5HT RECEPTOR STIMULATION (1987) (0)
- METABOLISM OFAN ORAL TRYPTOPHANLOAD. I:EFFECTSOFDOSEAND PRETREATMENTWITHTRYPTOPHAN (1980) (0)
- A Brief History of Psychopharmacology (2020) (0)
- THE METABOLISM AND FUNCTION OF MONOAMINES IN IRON-DEFICIENT RATS (1979) (0)
- Recent preclinical studies on neurotransmitter function after ECS. (1988) (0)
- NORADRENERGIC TRANSMISSION IN THE PINEAL-GLAND DURING DESMETHYLIMIPRAMINE TREATMENT (1985) (0)
- β-Adrenoceptor agonists, ECT and other antidepressants: effects on serotonin biochemistry and function (1984) (0)
- Effect of anaesthetic administration on the appearance of enhanced monoamine-mediated behaviours following electroconvulsive shock (1980) (0)
- Experimental and clinical experiences with clomethiazole, NXY-059 and AR-R15896 (1999) (0)
- Some Processes Involved in Regulating the Function of Brain 5-Hydroxytryptamine (1975) (0)
- Some observations on the behavioural and biochemical effects of L-tryptophan plus a monoamine oxidase inhibitor in immature rats [proceedings]. (1979) (0)
- S.02.04 The effects of clomethiazole in animal models of stroke (1997) (0)
- [3H]1-[1-(2-Thienyl)-cyclohexyl]piperidine binding to the N-methyl-d-aspartic acid receptor complex (1988) (0)
- Proceedings: Human blood platelet aggregation induced by dopamine, 5-hydroxyptrypamine and analogues. (1975) (0)
- Behavioural Responses to L-Tryptophan and L-Dopa in Monoamine Oxidase Inhibitor Treated Rats (1979) (0)
- LIVERAND BRAIN TRYPTOPHANMETABOLISM FOLLOWINGHYDROCORTISONE ADMINISTRATION TO RATSAND GERBILS (1975) (0)
- β-Adrenoceptor agonists enhance the functional activity of brain 5-hydroxytryptamine: relationship to antidepressant activity (1983) (0)
- Enhanced Monoamine Behavioural Responses Following Repeated Electroconvulsive Shock to Rats and their Relevance to ECT (1979) (0)
- Letter: Amines, anticonvulsants, and epilepsy. (1975) (0)
- Effect of beta 2-adrenoceptor agonists on serotonin biochemistry and function. (1984) (0)
- Drug-induced alterations of the post-ictal seizure threshold increase (1981) (0)
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