Richard H. Ebright
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American molecular biologist
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#1590
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Microbiology
#90
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#112
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#40
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Molecular Biology
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#283
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#113
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Biology
Why Is Richard H. Ebright Influential?
(Suggest an Edit or Addition)According to Wikipedia, Richard High Ebright is an American molecular biologist. He is the Board of Governors Professor of Chemistry and Chemical Biology at Rutgers University and Laboratory Director at the Waksman Institute of Microbiology.
Richard H. Ebright's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Transcription activation by catabolite activator protein (CAP). (1999) (773)
- Dynamically driven protein allostery (2006) (575)
- HEN1 recognizes 21–24 nt small RNA duplexes and deposits a methyl group onto the 2′ OH of the 3′ terminal nucleotide (2006) (442)
- Promoter structure, promoter recognition, and transcription activation in prokaryotes (1994) (435)
- New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB. (1998) (433)
- Accurate FRET measurements within single diffusing biomolecules using alternating-laser excitation. (2005) (423)
- Initial Transcription by RNA Polymerase Proceeds Through a DNA-Scrunching Mechanism (2006) (413)
- Abortive Initiation and Productive Initiation by RNA Polymerase Involve DNA Scrunching (2006) (366)
- Structural Basis of Transcription Initiation (2012) (325)
- Catabolite activator protein: DNA binding and transcription activation. (2004) (304)
- Structural Organization of Bacterial RNA Polymerase Holoenzyme and the RNA Polymerase-Promoter Open Complex (2002) (294)
- Structural Organization of Bacterial RNA Polymerase Holoenzyme and the RNA Polymerase-Promoter Open Complex (2002) (294)
- Transcription activation at Class II CAP‐dependent promoters (1993) (290)
- Transcription Activation at Class II CAP-Dependent Promoters: Two Interactions between CAP and RNA Polymerase (1996) (275)
- RNA polymerase: structural similarities between bacterial RNA polymerase and eukaryotic RNA polymerase II. (2000) (274)
- Mechanism of ATP-dependent promoter melting by transcription factor IIH. (2000) (271)
- Domain organization of RNA polymerase α subunit: C-terminal 85 amino acids constitute a domain capable of dimerization and DNA binding (1994) (254)
- Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface. (1997) (250)
- Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly. (2001) (244)
- Random mutagenesis of gene-sized DNA molecules by use of PCR with Taq DNA polymerase. (1991) (242)
- Bacterial promoter architecture: subsite structure of UP elements and interactions with the carboxy-terminal domain of the RNA polymerase alpha subunit. (1999) (224)
- The RNA Polymerase “Switch Region” Is a Target for Inhibitors (2008) (218)
- Structural Basis of Transcription Activation: The CAP-αCTD-DNA Complex (2002) (215)
- Structural Basis of Transcription Activation: The CAP-αCTD-DNA Complex (2002) (215)
- DNA-binding determinants of the alpha subunit of RNA polymerase: novel DNA-binding domain architecture. (1996) (207)
- Opening and Closing of the Bacterial RNA Polymerase Clamp (2012) (204)
- Opening and Closing of the Bacterial RNA Polymerase Clamp (2012) (204)
- Structural basis for cAMP-mediated allosteric control of the catabolite activator protein (2009) (199)
- Antibacterial peptide microcin J25 inhibits transcription by binding within and obstructing the RNA polymerase secondary channel. (2004) (195)
- Mutations that alter the DNA sequence specificity of the catabolite gene activator protein of E. coli (1984) (193)
- Structure of antibacterial peptide microcin J25: a 21-residue lariat protoknot. (2003) (185)
- Translocation of σ70 with RNA Polymerase during Transcription Fluorescence Resonance Energy Transfer Assay for Movement Relative to DNA (2001) (183)
- Translocation of σ70 with RNA Polymerase during Transcription Fluorescence Resonance Energy Transfer Assay for Movement Relative to DNA (2001) (183)
- Inhibition of Bacterial RNA Polymerase by Streptolydigin: Stabilization of a Straight-Bridge-Helix Active-Center Conformation (2005) (182)
- Structural Organization of the RNA Polymerase-Promoter Open Complex (2000) (179)
- Site-specific incorporation of fluorescent probes into protein: hexahistidine-tag-mediated fluorescent labeling with (Ni(2+):nitrilotriacetic Acid (n)-fluorochrome conjugates. (2001) (173)
- Site-specific incorporation of fluorescent probes into protein: hexahistidine-tag-mediated fluorescent labeling with (Ni(2+):nitrilotriacetic Acid (n)-fluorochrome conjugates. (2001) (173)
- Transcription activation at Class I CAP‐dependent promoters (1993) (165)
- Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma (2016) (162)
- Consensus DNA site for the Escherichia coli catabolite gene activator protein (CAP): CAP exhibits a 450-fold higher affinity for the consensus DNA site than for the E. coli lac DNA site. (1989) (157)
- Consensus DNA site for the Escherichia coli catabolite gene activator protein (CAP): CAP exhibits a 450-fold higher affinity for the consensus DNA site than for the E. coli lac DNA site. (1989) (157)
- Fluorescence anisotropy: rapid, quantitative assay for protein-DNA and protein-protein interaction. (1996) (156)
- Promoter unwinding and promoter clearance by RNA polymerase: detection by single-molecule DNA nanomanipulation. (2004) (154)
- Interactions between RNA polymerase and the “core recognition element” counteract pausing (2014) (152)
- New target for inhibition of bacterial RNA polymerase: 'switch region'. (2011) (146)
- The mechanism of RNA 5′ capping with NAD+, NADH, and desphospho-CoA (2016) (146)
- New target for inhibition of bacterial RNA polymerase: 'switch region'. (2011) (146)
- Transcription activation at Class II CRP‐dependent promoters: identification of determinants in the C‐terminal domain of the RNA polymerase α subunit (1998) (143)
- The Escherichia coli RNA polymerase alpha subunit: structure and function. (1995) (140)
- The Initiation Factor TFE and the Elongation Factor Spt4/5 Compete for the RNAP Clamp during Transcription Initiation and Elongation (2011) (140)
- Identification of the activating region of catabolite gene activator protein (CAP): isolation and characterization of mutants of CAP specifically defective in transcription activation. (1993) (140)
- Direct Detection of Abortive RNA Transcripts in Vivo (2009) (132)
- Direct observation of abortive initiation and promoter escape within single immobilized transcription complexes. (2006) (132)
- Retention of transcription initiation factor sigma70 in transcription elongation: single-molecule analysis. (2005) (126)
- Rapid RNA polymerase genetics: one-day, no-column preparation of reconstituted recombinant Escherichia coli RNA polymerase. (1995) (121)
- Identification of the target of a transcription activator protein by protein-protein photocrosslinking. (1994) (119)
- Identification of the target of a transcription activator protein by protein-protein photocrosslinking. (1994) (119)
- Location, structure, and function of the target of a transcriptional activator protein. (1994) (117)
- Trajectory of DNA in the RNA polymerase II transcription preinitiation complex. (1997) (116)
- Thermodynamic and kinetic modeling of transcriptional pausing. (2006) (114)
- DNA sequence determinants for binding of the Escherichia coli catabolite gene activator protein. (1992) (112)
- DNA sequence determinants for binding of the Escherichia coli catabolite gene activator protein. (1992) (112)
- Structures of RNA polymerase-antibiotic complexes. (2009) (111)
- High-resolution mapping of nucleoprotein complexes by site-specific protein-DNA photocrosslinking: organization of the human TBP-TFIIA-TFIIB-DNA quaternary complex. (1996) (108)
- Structural basis of transcription activation: the CAP-alpha CTD-DNA complex. (2002) (108)
- High-resolution mapping of nucleoprotein complexes by site-specific protein-DNA photocrosslinking: organization of the human TBP-TFIIA-TFIIB-DNA quaternary complex. (1996) (108)
- Structural basis of transcription activation: the CAP-alpha CTD-DNA complex. (2002) (108)
- Response of RNA polymerase to ppGpp: requirement for the omega subunit and relief of this requirement by DksA. (2005) (106)
- Systematic Structure-Activity Analysis of Microcin J25* (2008) (105)
- Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase (2017) (104)
- Protein-protein interactions in eukaryotic transcription initiation: structure of the preinitiation complex. (1996) (100)
- The Infectious Diseases Society of America's 10 × '20 Initiative (10 New Systemic Antibacterial Agents US Food and Drug Administration Approved by 2020): Is 20 × '20 a Possibility? (2019) (98)
- Incorporation of an EDTA-metal complex at a rationally selected site within a protein: application to EDTA-iron DNA affinity cleaving with catabolite gene activator protein (CAP) and Cro. (1992) (94)
- Incorporation of an EDTA-metal complex at a rationally selected site within a protein: application to EDTA-iron DNA affinity cleaving with catabolite gene activator protein (CAP) and Cro. (1992) (94)
- Characterization of the activating region of Escherichia coli catabolite gene activator protein (CAP). II. Role at Class I and class II CAP-dependent promoters. (1994) (92)
- CAP interacts with RNA polymerase in solution in the absence of promoter DNA (1993) (90)
- CAP interacts with RNA polymerase in solution in the absence of promoter DNA (1993) (90)
- Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. (2017) (85)
- Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. (2017) (85)
- White Paper: Developing Antimicrobial Drugs for Resistant Pathogens, Narrow-Spectrum Indications, and Unmet Needs (2017) (82)
- Rifamycins do not function by allosteric modulation of binding of Mg2+ to the RNA polymerase active center (2008) (82)
- A single substitution in the putative helix‐turn‐helix motif of the pleiotropic activator PrfA attenuates Listeria monocytogenes virulence (1996) (79)
- The σ70 subunit of RNA polymerase mediates a promoter-proximal pause at the lac promoter (2004) (79)
- Role of glutamic acid-181 in DNA-sequence recognition by the catabolite gene activator protein (CAP) of Escherichia coli: altered DNA-sequence-recognition properties of [Val181]CAP and [Leu181]CAP. (1987) (78)
- Characterization of the activating region of Escherichia coli catabolite gene activator protein (CAP). I. Saturation and alanine-scanning mutagenesis. (1994) (78)
- Identification of the functional subunit of a dimeric transcription activator protein by use of oriented heterodimers (1993) (78)
- Determinants of the C-Terminal Domain of the Escherichia coli RNA Polymerase α Subunit Important for Transcription at Class I Cyclic AMP Receptor Protein-Dependent Promoters (2002) (78)
- Characterization of the activating region of Escherichia coli catabolite gene activator protein (CAP). I. Saturation and alanine-scanning mutagenesis. (1994) (78)
- Three-dimensional EM structure of an intact activator-dependent transcription initiation complex (2009) (78)
- The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: implications for transcription start-site selection. (2013) (77)
- The RNA polymerase II general transcription factors: past, present, and future. (1998) (76)
- The interaction between σ70 and the β-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation (2005) (75)
- The antibacterial threaded-lasso peptide capistruin inhibits bacterial RNA polymerase. (2011) (72)
- Functional Interaction between RNA Polymerase α Subunit C-Terminal Domain and σ70 in UP-Element- and Activator-Dependent Transcription (2003) (71)
- Single-molecule DNA nanomanipulation: Improved resolution through use of shorter DNA fragments (2005) (71)
- RNA Polymerase β′ Subunit: A Target of DNA Binding-Independent Activation (1997) (70)
- Structural basis of transcription-translation coupling (2020) (69)
- Transcription inhibition by the depsipeptide antibiotic salinamide A (2014) (67)
- Transcription inhibition by the depsipeptide antibiotic salinamide A (2014) (67)
- Mutational analysis of a transcriptional activation region of the VP16 protein of herpes simplex virus. (1998) (67)
- Aromatic hydrogen bond in sequence-specific protein DNA recognition (1996) (66)
- Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3). (2018) (65)
- Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: alteration of DNA binding specificity through alteration of DNA kinking. (2001) (65)
- Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3). (2018) (65)
- Determinants of RNA polymerase alpha subunit for interaction with beta, beta', and sigma subunits: hydroxyl-radical protein footprinting. (1996) (64)
- Massively Systematic Transcript End Readout, "MASTER": Transcription Start Site Selection, Transcriptional Slippage, and Transcript Yields. (2015) (62)
- Transcription Factor B Contacts Promoter DNA Near the Transcription Start Site of the Archaeal Transcription Initiation Complex* (2004) (62)
- Identification of an amino acid–base contact in the GCN4–DNA complex by bromouracil-mediated photocrosslinking (1992) (61)
- Identification of an amino acid–base contact in the GCN4–DNA complex by bromouracil-mediated photocrosslinking (1992) (61)
- Molecular basis of DNA sequence recognition by the catabolite gene activator protein: detailed inferences from three mutations that alter DNA sequence specificity. (1984) (59)
- GE23077 binds to the RNA polymerase ‘i’ and ‘i+1’ sites and prevents the binding of initiating nucleotides (2014) (59)
- GE23077 binds to the RNA polymerase ‘i’ and ‘i+1’ sites and prevents the binding of initiating nucleotides (2014) (59)
- Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: DNA binding specificity based on energetics of DNA kinking. (2001) (56)
- Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection (2016) (55)
- S-[2-(4-azidosalicylamido)ethylthio]-2-thiopyridine: radioiodinatable, cleavable, photoactivatible cross-linking agent. (1996) (54)
- Analogs of cyclic AMP that elicit the biochemically defined conformational change in catabolite gene activator protein (CAP) but do not stimulate binding to DNA. (1985) (54)
- S-[2-(4-azidosalicylamido)ethylthio]-2-thiopyridine: radioiodinatable, cleavable, photoactivatible cross-linking agent. (1996) (54)
- Orientation of OmpR monomers within an OmpR:DNA complex determined by DNA affinity cleaving. (1999) (52)
- Mean DNA bend angle and distribution of DNA bend angles in the CAP-DNA complex in solution. (2001) (51)
- Mean DNA bend angle and distribution of DNA bend angles in the CAP-DNA complex in solution. (2001) (51)
- Identification of a contact between arginine-180 of the catabolite gene activator protein (CAP) and base pair 5 of the DNA site in the CAP-DNA complex. (1990) (50)
- The functional subunit of a dimeric transcription activator protein depends on promoter architecture. (1994) (49)
- Transcription activation at the Escherichia coli uhpT promoter by the catabolite gene activator protein (1995) (48)
- Roles of the Histone H2A-H2B Dimers and the (H3-H4)2Tetramer in Nucleosome Remodeling by the SWI-SNF Complex* (2000) (48)
- Structural basis of transcription activation (2016) (48)
- “CapZyme-Seq” comprehensively defines promoter-sequence determinants for RNA 5’ capping with NAD+ (2017) (48)
- Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps. (2006) (46)
- The functional subunit of a dimeric transcription activator protein depends on promoter architecture (1994) (46)
- Fluorescence resonance energy transfer (FRET) in analysis of transcription-complex structure and function. (2003) (45)
- Fluorescence resonance energy transfer (FRET) in analysis of transcription-complex structure and function. (2003) (45)
- Determination of the orientation of a DNA binding motif in a protein-DNA complex by photocrosslinking. (1992) (44)
- The interaction between sigma70 and the beta-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation. (2005) (44)
- Substitution of 2 base pairs (1 base pair per DNA half-site) within the Escherichia coli lac promoter DNA site for catabolite gene activator protein places the lac promoter in the FNR regulon. (1990) (44)
- Activation mutants in yeast RNA polymerase II subunit RPB3 provide evidence for a structurally conserved surface required for activation in eukaryotes and bacteria. (2000) (44)
- Determination of the orientation of a DNA binding motif in a protein-DNA complex by photocrosslinking. (1992) (44)
- Highly efficient 5' capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase (2018) (44)
- Conversion of a helix-turn-helix motif sequence-specific DNA binding protein into a site-specific DNA cleavage agent. (1990) (43)
- Conversion of a helix-turn-helix motif sequence-specific DNA binding protein into a site-specific DNA cleavage agent. (1990) (43)
- Escherichia coli RNA polymerase holoenzyme: rapid reconstitution from recombinant alpha, beta, beta', and sigma subunits. (1996) (43)
- The sigma 70 subunit of RNA polymerase mediates a promoter-proximal pause at the lac promoter. (2004) (42)
- High-specificity DNA cleavage agent: design and application to kilobase and megabase DNA substrates. (1994) (41)
- High-specificity DNA cleavage agent: design and application to kilobase and megabase DNA substrates. (1994) (41)
- Structural basis of Mycobacterium tuberculosis transcription and transcription inhibition (2017) (40)
- Distance-restrained docking of rifampicin and rifamycin SV to RNA polymerase using systematic FRET measurements: developing benchmarks of model quality and reliability. (2005) (40)
- Derivatives of CAP having no solvent-accessible cysteine residues, or having a unique solvent-accessible cysteine residue at amino acid 2 of the helix-turn-helix motif. (1991) (40)
- Structural basis of Mycobacterium tuberculosis transcription and transcription inhibition (2017) (40)
- Derivatives of CAP having no solvent-accessible cysteine residues, or having a unique solvent-accessible cysteine residue at amino acid 2 of the helix-turn-helix motif. (1991) (40)
- Salinamide F, new depsipeptide antibiotic and inhibitor of bacterial RNA polymerase from a marine-derived Streptomyces sp. (2014) (38)
- Pause sequences facilitate entry into long-lived paused states by reducing RNA polymerase transcription rates (2018) (36)
- DNA binding specificity and sequence of Xanthomonas campestris catabolite gene activator protein-like protein (1992) (35)
- The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp (2018) (35)
- Analysis of the Pseudouridimycin Biosynthetic Pathway Provides Insights into the Formation of C-nucleoside Antibiotics. (2018) (33)
- Binding of 2-hydroxybenzo(a)pyrene to estrogen receptors in rat cytosol. (1986) (32)
- Interactions between RNA polymerase and the core recognition element are a determinant of transcription start site selection (2016) (32)
- Structural basis of ECF-σ-factor-dependent transcription initiation (2018) (31)
- Upstream promoter sequences and αCTD mediate stable DNA wrapping within the RNA polymerase–promoter open complex (2007) (31)
- Functional interaction between RNA polymerase alpha subunit C-terminal domain and sigma70 in UP-element- and activator-dependent transcription. (2003) (30)
- DNA affinity cleaving analysis of homeodomain-DNA interaction: identification of homeodomain consensus sites in genomic DNA. (1994) (29)
- An Open Letter to Elias Zerhouni (2005) (29)
- DNA affinity cleaving analysis of homeodomain-DNA interaction: identification of homeodomain consensus sites in genomic DNA. (1994) (29)
- Structural basis of Q-dependent antitermination (2019) (28)
- Mechanism for transcriptional action of cyclic AMP in Escherichia coli: entry into DNA to disrupt DNA secondary structure. (1981) (28)
- Mechanisms of viral activators. (1998) (28)
- Site-specific protein-DNA photocrosslinking. Analysis of bacterial transcription initiation complexes. (2001) (27)
- Catabolite gene activator protein (CAP) is not an "acidic activating region" transcription activator protein. Negatively charged amino acids of CAP that are solvent-accessible in the CAP-DNA complex play no role in transcription activation at the lac promoter. (1992) (26)
- Single-molecule DNA nanomanipulation: detection of promoter-unwinding events by RNA polymerase. (2003) (26)
- Catabolite gene activator protein (CAP) is not an "acidic activating region" transcription activator protein. Negatively charged amino acids of CAP that are solvent-accessible in the CAP-DNA complex play no role in transcription activation at the lac promoter. (1992) (26)
- Requirement for two copies of RNA polymerase alpha subunit C-terminal domain for synergistic transcription activation at complex bacterial promoters. (2002) (25)
- Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. (2015) (24)
- Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. (2015) (24)
- Azide-specific labeling of biomolecules by Staudinger-Bertozzi ligation phosphine derivatives of fluorescent probes suitable for single-molecule fluorescence spectroscopy. (2010) (23)
- RNA polymerase beta' subunit: a target of DNA binding-independent activation. (1997) (23)
- Azide-specific labeling of biomolecules by Staudinger-Bertozzi ligation phosphine derivatives of fluorescent probes suitable for single-molecule fluorescence spectroscopy. (2010) (23)
- RNA polymerase-DNA interaction: structures of intermediate, open, and elongation complexes. (1998) (22)
- Frequency, Spectrum, and Nonzero Fitness Costs of Resistance to Myxopyronin in Staphylococcus aureus (2012) (22)
- RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription (2019) (22)
- Frequency, Spectrum, and Nonzero Fitness Costs of Resistance to Myxopyronin in Staphylococcus aureus (2012) (22)
- Retention of transcription initiation factor sigma(70) in transcription elongation: Single-molecule analysis - eScholarship (2005) (21)
- Structure of the LexA repressor-DNA complex probed by affinity cleavage and affinity photo-cross-linking. (1996) (20)
- Artificial Sequence-Specific DNA Binding Peptides: Branched-Chain Basic Regions (1996) (19)
- The mechanism of variability in transcription start site selection (2017) (18)
- Structural basis of ECF-sigma-factor-dependent transcription initiation. (2019) (18)
- Closing and opening of the RNA polymerase trigger loop (2019) (17)
- Phenyl-azide-mediated photocrosslinking analysis of Cro-DNA interaction. (1993) (17)
- Identification of the Subunit of cAMP Receptor Protein (CRP) That Functionally Interacts with CytR in CRP-CytR-mediated Transcriptional Repression* (2000) (16)
- The fight over flu (2012) (15)
- An appeal for an objective, open, and transparent scientific debate about the origin of SARS-CoV-2 (2021) (14)
- Synthesis and evaluation of novel analogues of ripostatins. (2014) (14)
- Structure of the DNA-binding and RNA-polymerase-binding region of transcription antitermination factor λQ. (2014) (14)
- Corrected nucleotide sequence of M13mp18 gene III. (1992) (14)
- XACT-seq comprehensively defines the promoter-position and promoter-sequence determinants for initial-transcription pausing (2019) (13)
- Affinity Selection-Mass Spectrometry Identifies a Novel Antibacterial RNA Polymerase Inhibitor. (2017) (13)
- Discovery, properties, and biosynthesis of pseudouridimycin, an antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase (2019) (12)
- Site-specific incorporation of probes into RNA polymerase by unnatural-amino-acid mutagenesis and Staudinger-Bertozzi ligation. (2015) (11)
- Site-specific incorporation of probes into RNA polymerase by unnatural-amino-acid mutagenesis and Staudinger-Bertozzi ligation. (2015) (11)
- N-(iodoacetyl)-p-phenylenediamine-EDTA: a reagent for high-efficiency incorporation of an EDTA-metal complex at a rationally selected site within a protein. (1993) (11)
- RNA polymerase clamp conformational dynamics: long-lived states and modulation by crowding, cations, and nonspecific DNA binding (2020) (11)
- N-(iodoacetyl)-p-phenylenediamine-EDTA: a reagent for high-efficiency incorporation of an EDTA-metal complex at a rationally selected site within a protein. (1993) (11)
- CHAPTER 7 – Steroid Hormone Action Interpreted from X-Ray Crystallographic Studies (1984) (11)
- Erratum: Structure of the CAP-DNA complex at 2.5 Å resolution: A complete picture of the protein-DNA Interface (Journal of Molecular Biology (1996) 260:3 (395-408)) (2011) (10)
- Erratum: Structure of the CAP-DNA complex at 2.5 Å resolution: A complete picture of the protein-DNA Interface (Journal of Molecular Biology (1996) 260:3 (395-408)) (2011) (10)
- Functionalised bicyclic tetramates derived from cysteine as antibacterial agents. (2019) (9)
- Orientation of the Lac repressor DNA binding domain in complex with the left lac operator half site characterized by affinity cleaving. (1991) (8)
- Transcriptome Complexity in a Genome-Reduced Bacterium (2009) (8)
- Static and kinetic site-specific protein-DNA photocrosslinking: analysis of bacterial transcription initiation complexes. (2009) (8)
- DNA-sequence recognition by CAP: role of the adenine N6 atom of base pair 6 of the DNA site. (1990) (7)
- Structural basis of Rho-dependent transcription termination (2022) (7)
- Bioweapon agents: more access means more risk (2002) (7)
- Lysine 188 of the catabolite gene activator protein (CAP) plays no role in specificity at base pair 7 of the DNA half site. (1990) (7)
- DNA-sequence recognition by CAP: role of the adenine N6 atom of base pair 6 of the DNA site. (1990) (7)
- Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens (2022) (7)
- Erratum to "Structure of the CAP-DNA Complex at 2.5 Å Resolution: A Complete Picture of the Protein-DNA Interface" (J. Mol. Biol. 260/3 (1996) 395-408) (2011) (7)
- Erratum to "Structure of the CAP-DNA Complex at 2.5 Å Resolution: A Complete Picture of the Protein-DNA Interface" (J. Mol. Biol. 260/3 (1996) 395-408) (2011) (7)
- Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain (2021) (6)
- RNA Capping by Transcription Initiation with Non-canonical Initiating Nucleotides (NCINs): Determination of Relative Efficiencies of Transcription Initiation with NCINs and NTPs. (2017) (6)
- Transcription initiation at a consensus bacterial promoter proceeds via a “bind-unwind-load-and-lock” mechanism (2021) (6)
- Refinement strategies for protein–nucleic acid complexes (1996) (6)
- Structural basis for chemotherapeutic action of antiestrogens. (1985) (5)
- Nonradioactive, ultrasensitive site-specific protein–protein photocrosslinking: interactions of α-helix 2 of TATA-binding protein with general transcription factor TFIIA and transcriptional repressor NC2 (2008) (5)
- Nonradioactive, ultrasensitive site-specific protein–protein photocrosslinking: interactions of α-helix 2 of TATA-binding protein with general transcription factor TFIIA and transcriptional repressor NC2 (2008) (5)
- Structural basis of transcription inhibition by fidaxomicin (lipiarmycin A3) (2017) (5)
- Structural basis of transcription inhibition by fidaxomicin (lipiarmycin A3) (2017) (5)
- A peptide-acridine conjugate with ribonucleolytic activity (1992) (5)
- CHAPTER 1. The Transition from Transcription Initiation to Transcription Elongation: Start-site Selection, Initial Transcription, and Promoter Escape (2021) (5)
- The catabolite gene activator protein (CAP) is not required for indole-3-acetic acid to activate transcription of the araBAD operon of Escherichia coli K-12 (2004) (4)
- One-dimensional sliding assists σ70-dependent promoter binding by Escherichia coli RNA polymerase (2018) (3)
- Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli (2021) (3)
- Structural and mechanistic basis of σ-dependent transcriptional pausing (2022) (3)
- Chromatographic Purification of Non-Ionic Methylphosphonate Oligodeoxyribonucleosides (1988) (3)
- RNA Polymerase Reaches 60: Transcription Initiation, Elongation, Termination, and Regulation in Prokaryotes. (2019) (3)
- Structural and mechanistic basis of reiterative transcription initiation (2021) (2)
- Author response: Highly efficient 5' capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase (2018) (2)
- Redesign of Rifamycin Antibiotics to Overcome ADP‐Ribosylation‐Mediated Resistance (2022) (2)
- Mitochondrial RNA capping: highly efficient 5’-RNA capping with NAD+ and NADH by yeast and human mitochondrial RNA polymerase (2018) (2)
- Transcription initiation at a consensus bacterial promoter proceeds via a ‘bind-unwind-load-and-lock’ mechanism (2021) (2)
- Structural basis of transcription antitermination by Qλ: NusA induces refolding of Qλ to form nozzle for RNA polymerase exit channel (2022) (2)
- Correction to: Salinamide F, new depsipeptide antibiotic and inhibitor of bacterial RNA polymerase from a marine-derived Streptomyces sp. (2022) (2)
- Total Synthesis of Pargamicin A. (2022) (1)
- Novel RNA polymerase inhibitor found in soil extracts provides hope for future antibacterial drugs. (2017) (1)
- Mitigate the risks of release (2012) (1)
- RNA Polymerase Translocation in Processive Transcription Elongation and Pausing: Dynamics, Force-Dependence, and Modulation by Sequence-Specific RNAP-DNA Interactions (2017) (1)
- Structural and mechanistic basis of RNA extension in reiterative transcription initiation: RNA slipping without DNA scrunching (2021) (1)
- Staphylococcus aureus Costs of Resistance to Myxopyronin in Frequency, Spectrum, and Nonzero Fitness (2012) (1)
- Staphylococcus aureus Costs of Resistance to Myxopyronin in Frequency, Spectrum, and Nonzero Fitness (2012) (1)
- Antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase: pseudouridimycin (2017) (1)
- Nanopore Tweezers Reveal Detailed RNA Polymerase Dynamics at a Sequence-Specific Pause Element (2018) (1)
- Classical genetics and site directed mutagenesis in the study of the specific interaction with DNA of CAP, the cyclic AMP receptor protein in E. coli K 12 (1986) (1)
- Reply to Paul and Leibovici. (2018) (1)
- Crystal structure of Thermus thermophilus pre-insertion substrate complex for de novo transcription initiation (2014) (1)
- Metabolomic investigation of the pseudouridimycin producer, a prolific streptomycete (2020) (0)
- Escherichia coli transcription-translation complex B (TTC-B) containing an 30 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site (2020) (0)
- Escherichia coli transcription-translation complex C1 (TTC-C1) containing a 27 nt long mRNA spacer, NusG, and fMet-tRNAs at P-site and E-site (2020) (0)
- Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 3 nt (2020) (0)
- Single‐molecule analysis of transcription (2009) (0)
- Sensory Biology Plant Genetics Protein Biochemistry Developmental Biology Computational Bioinformatics Laboratory Plastid Molecular Genetics Molecular Genetics of Meiotic Recombination & Chromosome Segregation Molecular Biology of Plant Development Plant Genomics & Bioinformatics Regulation of Gene (0)
- Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 (2014) (0)
- Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo (2016) (0)
- Crystal structure of MTB sigma L transcription initiation complex with 5 nt long RNA primer (2020) (0)
- Single-Molecule Picometer Resolution Nanopore Tweezers Resolution (2017) (0)
- Determining Dynamics of RNA Polymerase Elongation and Pausing using Nanopore Tweezers (2019) (0)
- Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin (2005) (0)
- Modeling Promoter Escape (2010) (0)
- PNAS Plus Significance Statements (2016) (0)
- Crystal structure of Escherichia coli RNA polymerase in complex with CBR703 (2015) (0)
- Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3 nt of RNA (2017) (0)
- Studies with 2-(butyldiphenylsiloxymethyl)-benzoyl protected oligodeoxyribonucleotides (1993) (0)
- Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 7 nt (2020) (0)
- Escherichia coli transcription-translation complex C5 (TTC-C5) containing mRNA with a 21 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site (2020) (0)
- Q21 transcription antitermination complex: loaded complex (2019) (0)
- Escherichia coli transcription-translation complex D3 (TTC-D3) containing mRNA with a 21 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site (2020) (0)
- Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 4 nt (2020) (0)
- RNA POLYMERASE INHIBITOR ACTIVITY AGAINST STAPHYLOCOCCUS EPIDERMIDIS BIOFILMS (2014) (0)
- Crystal structure of Thermus thermophilus transcription initiation complex with GpA and CMPcPP (2017) (0)
- Soma Mandal Graduate Assistant (0)
- Sequence-Specific RNAP-DNA Interactions in Transcription Initiation and Elongation: Core Recognition Element (CRE) (2014) (0)
- Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 2 nt (2020) (0)
- Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077, ATP, and CMPcPP (2014) (0)
- Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF selenomethionine-labelled sigma factor L) with 6 nt spacer (2019) (0)
- Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 4nt spacer (2019) (0)
- Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 6 nt (2020) (0)
- The interaction between (cid:1) 70 and the (cid:2) -flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation (2005) (0)
- Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA (2012) (0)
- Interactions between CRP and the C-terminal domain of the RNA polymerase alpha subunit (1999) (0)
- Crystal structure of Escherichia coli RNA polymerase in complex with CBRH16-Br (2015) (0)
- Fractional‐nucleotide translocation in sequence‐dependent pausing by RNA polymerase: Single‐molecule picometer‐resolution nanopore tweezers (SPRNT) (2019) (0)
- Escherichia coli transcription-translation complex C4 (TTC-C4) containing mRNA with a 21 nt long spacer, transcription factor NusG, and fMet-tRNAs at P-site and E-site (2020) (0)
- New Insights into Transcriptional Pausing using Ultra-high Resolution Optical Tweezers and Novel Analysis Algorithms (2018) (0)
- Transcription antitermination factor Q21 (2019) (0)
- Color coding and in situ query of matrix-coupled chemical compounds (1998) (0)
- Escherichia coli transcription-translation complex D1 (TTC-D1) containing mRNA with a 27 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site (2020) (0)
- Structural basis of ECF-σ-factor-dependent transcription initiation (2019) (0)
- System and method for controlling a video recording device (1991) (0)
- Escherichia coli transcription-translation complex A1 (TTC-A1) containing an 18 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site (2020) (0)
- Tracking Single RNAP Enzyme Steps and State Transitions During Elongation and Pausing with Nanopore Tweezers (2020) (0)
- Letters: Affirmative Action: A Quota System (1995) (0)
- Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 4 nt (2020) (0)
- Crystal structure of Thermus thermophilus RNA polymerase transcription initiation complex soaked with GE23077 and rifamycin SV (2014) (0)
- Escherichia coli transcription-translation complex A2 (TTC-A2) containing a 15 nt long mRNA spacer, NusG, and fMet-tRNAs at P-site and E-site (2020) (0)
- Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 and rifampicin (2014) (0)
- Escherichia coli transcription-translation complex C6 (TTC-C6) containing mRNA with a 21 nt long spacer, NusA, and fMet-tRNAs at E-site and P-site (2020) (0)
- Escherichia coli transcription-translation complex B (TTC-B) containing an 24 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site (2020) (0)
- Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 5 nt (2020) (0)
- Escherichia coli transcription-translation complex D2 (TTC-D2) containing mRNA with a 27 nt long spacer (2020) (0)
- Waksman Institute Areas of Specialization Sensory Biology Plant Genetics Protein Biochemistry Developmental Biology Molecular Genetics of Leaf Development Computational Bioinformatics Laboratory Plastid Molecular Genetics Molecular Genetics of Meiotic Recombination & Chromosome Segregation Molecular (0)
- Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 5 nt (2020) (0)
- Crystal structure of MTB sigma L transcription initiation complex with 6 nt long RNA primer (2020) (0)
- Promoter melting by RNA polymerase: Detection and analysis by single-molecule DNA nanomanipulation (2002) (0)
- Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site (2020) (0)
- Crystal structure of Thermus thermophilus product complex for transcription initiation with ATP and CTP (2016) (0)
- Crystal structure of Thermus thermophilus transcription initiation complex containing 5-BrU at template-strand position +1 (2012) (0)
- Escherichia coli transcription-translation complex A1 (TTC-A1) containing a 21 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site (2020) (0)
- Crystal structure of Mycobacterium tuberculosis transcription initiation complex (2017) (0)
- Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA in complex with Rifampin (2017) (0)
- Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B2 (TTC-B2) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site (2020) (0)
- Crystal structure of Thermus thermophilus RNA polymerase core enzyme (2018) (0)
- Orientation oftheLacrepressor DNAbinding domain in complex withtheleft lacoperator half site characterized byaffinity cleaving (1991) (0)
- The mechanism of transcription start site selection (2017) (0)
- T. thermophilus transcription initiation complex having a RRR discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 7 (RPo-GGG-7) (2016) (0)
- Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 27 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site (2020) (0)
- How Low Can You Go ? Physical Production Mechanism of Elephant Infrasonic Vocalizations (2012) (0)
- Q21 transcription antitermination complex: loading complex (2019) (0)
- Structure of the E. coli alpha C-terminal domain of RNA polymerase in complex with CAP and DNA (2002) (0)
- Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2ntRNA in complex with Rifampin (2017) (0)
- This debate is a 'non-subject' (1999) (0)
- Therapeutics for Tuberculosis: Novel Inhibitors of Mycobacterial RNA Polymerase (2017) (0)
- Crystal structure of antitermination protein Q from bacteriophage lambda. Northeast Structural Genomics Consortium target OR18A. (2013) (0)
- Escherichia coli transcription-translation complex B (TTC-B) containing an 27 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site (2020) (0)
- Structure of the E. coli alpha C-terminal domain of RNA polymerase in complex with CAP and DNA (2002) (0)
- Crystal structure of Thermus thermophilus transcription initiation complex comprising a truncated sigma finger (2020) (0)
- Abstract LB-290: Multiple distinct mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma (2015) (0)
- Waksman Institute Areas of Specialization Sensory Biology Plant Genetics Protein Biochemistry Developmental Biology Molecular Genetics of Leaf Development Computational Bioinformatics Laboratory Plastid Molecular Genetics Molecular Genetics of Meiotic Recombination & Chromosome Segregation Molecular (0)
- Vvedenskaya element ' ' counteract pausing Interactions between RNA polymerase and the ' ' core recognition (2014) (0)
- Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM) (2017) (0)
- Soma Mandal Graduate Assistant (0)
- How Low Can You Go ? Physical Production Mechanism of Elephant Infrasonic Vocalizations (2012) (0)
- Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer (2019) (0)
- Identification and Structural Modeling of the RNA Polymerase Omega Subunits in Chlamydiae and Other Obligate Intracellular Bacteria (2023) (0)
- Determination oftheorientation ofaDNA binding motifina protein-DNA complex byphotocrosslinkin g (1992) (0)
- RNA Polymerase Transcription Elongation Pasuing and Termination Investigated at Super Resolution with the Mspa Nanopore (2017) (0)
- Abstract IA18: Molecular signatures of circulating tumor cells (2020) (0)
- Antisense DNA-analogs. Inhibition of human immunodeficiency virus. (1990) (0)
- Pause sequences facilitate entry into long-lived paused states by reducing RNA polymerase transcription rates (2018) (0)
- Crystal structure of Thermus thermophilus transcription initiation complex (2012) (0)
- Sensory Biology Plant Genetics Protein Biochemistry Developmental Biology Computational Bioinformatics Laboratory Plastid Molecular Genetics Molecular Genetics of Meiotic Recombination & Chromosome Segregation Molecular Biology of Plant Development Plant Genomics & Bioinformatics Regulation of Gene (0)
- Crystal structure of beta'MtbSI of Mycobacterium tuberculosis RNA polymerase (2017) (0)
- Escherichia coli transcription-translation complex A (TTC-A) containing an 24 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site (2020) (0)
- Escherichia coli transcription-translation complex A1 (TTC-A1) containing an 15 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site (2020) (0)
- Training grants [2] (1995) (0)
- Crystal structure of MTB sigma L transcription initiation complex with 9 nt long RNA primer (2020) (0)
- Abstract LB-165: Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma (2016) (0)
- Single-molecule observations of DNA denaturation: mechanical and enzymatic effects (2003) (0)
- Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-AAP1 and Rifampin (2017) (0)
- Cryo-EM structure of Escherichia coli transcription-translation complex A (TTC-A) containing mRNA with a 12 nt long spacer (2020) (0)
- Crystal structure of Escherichia coli RNA polymerase holoenzyme (2014) (0)
- Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 30 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site (2020) (0)
- Transcription antitermination factor Q21 in complex with Q21-binding-element DNA (2019) (0)
- Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 6 nt (2020) (0)
- Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 5nt spacer (2019) (0)
- Transcription antitermination factor Q21, SeMet-derivative (2019) (0)
- CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION (2001) (0)
- Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B1 (TTC-B1) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site (2020) (0)
- Chinese scientists and US leadership in the life sciences (2019) (0)
- Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) with 6 nt spacer and bromine labelled in position ""-11 (2019) (0)
- Crystal structure of Thermus thermophilus RNA polymerase holoenzyme at 3.3 angstroms resolution (2005) (0)
- CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX + ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (1997) (0)
- Crystal structure of Escherichia coli RNA polymerase in complex with CBRP18 (2015) (0)
- Escherichia coli transcription-translation complex A1 (TTC-A1) containing mRNA with a 15 nt long spacer, fMet-tRNAs at E-site and P-site, and lacking transcription factor NusG (2020) (0)
- Identification and structural modeling of the chlamydial RNA polymerase omega subunit (2022) (0)
- Crystal structure of Thermus thermophilus product complex for transcription initiation with 3'-dephosphate-CoA and CTP (2016) (0)
- Site-specific protein-DNA photo-cross-linking: analysis of structural organization of protein-DNA and multiprotein-DNA complexes. (2006) (0)
- PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES (2001) (0)
- Crystal structure of Thermus thermophilus RNA polymerase holoenzyme in complex with GE23077 (2014) (0)
- Single-molecule Analysis Reveals the Mechanism for DNA Opening in Transcription Initiation (2020) (0)
- Special issue: Mechanisms of transcription (2011) (0)
- Kinetic Modelling of Transcription Elongation (2006) (0)
- Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A (2014) (0)
- Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA in complex with Rifampin (2017) (0)
- Escherichia coli transcription-translation complex C3 (TTC-C3) containing mRNA with a 27 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site (2020) (0)
- Thermodynamic Model of Transcription Elongation (2006) (0)
- Escherichia coli transcription-translation complex C2 (TTC-C2) containing a 27 nt long mRNA spacer (2020) (0)
- Flexibility in Transcription Start-Site Selection by RNA Polymerase Involves Transcription-Bubble Expansion (“Scrunching”) or Contraction (“Unscrunching”) (2013) (0)
- Open Letter 3 to the World Health Organization and the Members of its Executive Board (2021) (0)
- In transcription antitermination by Qλ, NusA induces refolding of Qλ to form a nozzle that extends the RNA polymerase RNA-exit channel (2022) (0)
- Open Letter 1: Call for a Full and Unrestricted International Forensic Investigation into the Origins of COVID-19 (2021) (0)
- Author response: The mechanism of variability in transcription start site selection (2017) (0)
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