Richard Hynes

Q: What Schools Are Affiliated With Richard Hynes

Richard Hynes is affiliated with the following schools: California Institute of Technology, Rockefeller University, Massachusetts Institute of Technology, Baylor College of Medicine, University of Toronto, Kyoto University, Harvard University, University of Cambridge

Richard Hynes's AcademicInfluence.com Rankings

Richard Hynes

Biology

#850

World Rank

#1481

Historical Rank

#457

USA Rank

Molecular Biology

#64

World Rank

#65

Historical Rank

#44

USA Rank

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Biology

Why Is Richard Hynes Influential?

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According to Wikipedia, Richard Olding Hynes is a British biologist, a Howard Hughes Medical Institute Investigator, and the Daniel K. Ludwig Professor for Cancer Research at the Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology . His research focuses on cell adhesion and the interactions between cells and the extracellular matrix, with a particular interest in understanding molecular mechanisms of cancer metastasis. He is well known as a co-discoverer of fibronectin molecules, a discovery that has been listed by Thomson Scientific ScienceWatch as a Nobel Prize candidate.

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Richard Hynes's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Integrins: Versatility, modulation, and signaling in cell adhesion (1992) (10314)
Integrins Bidirectional, Allosteric Signaling Machines (2002) (8258)
Integrins: A family of cell surface receptors (1987) (4154)
The Extracellular Matrix: Not Just Pretty Fibrils (2009) (2800)
Complete Replication of Hepatitis C Virus in Cell Culture (2005) (2366)
Genomic analysis of metastasis reveals an essential role for RhoC (2000) (1508)
Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis. (2011) (1451)
A framework for advancing our understanding of cancer-associated fibroblasts (2020) (1376)
Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. (1993) (1327)
Fibronectins: multifunctional modular glycoproteins (1982) (1260)
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice (1993) (1107)
Thrombospondin-1 Is a Major Activator of TGF-β1 In Vivo (1998) (1062)
The Genome of the Sea Urchin Strongylocentrotus purpuratus (2006) (1056)
Comparative genomics of the eukaryotes. (2000) (1031)
Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts (1999) (963)
Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons (1992) (900)
Overview of the matrisome--an inventory of extracellular matrix constituents and functions. (2012) (850)
Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development. (1995) (847)
Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin (1986) (834)
The Matrisome: In Silico Definition and In Vivo Characterization by Proteomics of Normal and Tumor Extracellular Matrices* (2011) (800)
Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. (1999) (800)
CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism (2002) (770)
Developmental defects in mouse embryos lacking N-cadherin. (1997) (753)
The Talin Head Domain Binds to Integrin β Subunit Cytoplasmic Tails and Regulates Integrin Activation* (1999) (730)
Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts. (2000) (727)
Embryonic mesodermal defects in alpha 5 integrin-deficient mice. (1993) (709)
Extensive Vasculogenesis, Angiogenesis, and Organogenesis Precede Lethality in Mice Lacking All αv Integrins (1998) (701)
Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere. (2002) (680)
Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy. (2016) (675)
Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases (1998) (660)
Cell surface proteins and malignant transformation. (1976) (649)
Self-complementary oligopeptide matrices support mammalian cell attachment. (1995) (637)
The extracellular matrix: Tools and insights for the "omics" era. (2015) (635)
Three different fibronectin mRNAs arise by alternative splicing within the coding region (1983) (611)
Alteration of cell-surface proteins by viral transformation and by proteolysis. (1973) (607)
Changes in integrin receptors on oncogenically transformed cells (1989) (577)
Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor α 4 β 1 (1990) (570)
A reevaluation of integrins as regulators of angiogenesis (2002) (548)
Molecular biology of fibronectin. (1985) (543)
Susceptibility to Infection and Altered Hematopoiesis in Mice Deficient in Both P- and E-Selectins (1996) (540)
A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. (1998) (531)
Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein. (1991) (527)
Plakoglobin: A protein common to different kinds of intercellular adhering junctions (1986) (516)
The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins (1986) (512)
Thrombospondin-1 is a major activator of TGF-beta1 in vivo. (1998) (508)
The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain (2012) (506)
Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. (2000) (506)
Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. (1995) (506)
Physiological levels of tumstatin, a fragment of collagen IV α3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via αVβ3 integrin (2003) (489)
Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat (1989) (489)
The combined role of P- and E-selectins in atherosclerosis. (1998) (487)
Cell adhesion: old and new questions. (1999) (476)
The Evolution of Cell Adhesion (2000) (475)
Hematopoietic Progenitor Cell Rolling in Bone Marrow Microvessels: Parallel Contributions by Endothelial Selectins and Vascular Cell Adhesion Molecule 1 (1998) (472)
Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor (2001) (462)
Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors (1988) (455)
Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia. (1998) (445)
Tumstatin, an Endothelial Cell-Specific Inhibitor of Protein Synthesis (2002) (425)
α3β1 Integrin Is Required for Normal Development of the Epidermal Basement Membrane (1997) (422)
Relationships between fibronectin (LETS protein) and actin (1978) (422)
Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis (2002) (410)
Restoration of normal morphology, adhesion and cytoskeleton in transformed cells by addition of a transformation-sensitive surface protein (1977) (402)
Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins (2002) (400)
Platelets guide the formation of early metastatic niches (2014) (389)
10 nm filaments in normal and transformed cells (1978) (388)
Syndecan-4 signals cooperatively with integrins in a Rho-dependent manner in the assembly of focal adhesions and actin stress fibers. (1999) (376)
The initial hours of metastasis: the importance of cooperative host-tumor cell interactions during hematogenous dissemination. (2012) (359)
Antibodies to the conserved cytoplasmic domain of the integrin beta 1 subunit react with proteins in vertebrates, invertebrates, and fungi (1988) (334)
Differential Requirements for α4 Integrins during Fetal and Adult Hematopoiesis (1996) (332)
Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. (2002) (328)
Sequence and domain structure of talin (1990) (323)
Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. (2000) (320)
Targeted mutations in cell adhesion genes: what have we learned from them? (1996) (318)
Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin. (2003) (311)
Fibronectins are essential for heart and blood vessel morphogenesis but are dispensable for initial specification of precursor cells. (1997) (302)
Targeted Mutation of TNF Receptor I Rescues the RelA-Deficient Mouse and Reveals a Critical Role for NF-κB in Leukocyte Recruitment1 (2001) (292)
Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation. (1996) (287)
Multiple sites of alternative splicing of the rat fibronectin gene transcript. (1987) (286)
Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. (2002) (284)
Precocious Mammary Gland Development in P-Cadherin–deficient Mice (1997) (282)
Plasma fibronectin is synthesized and secreted by hepatocytes. (1983) (277)
Transformed mammalian cells secrete specific proteins and phosphoproteins (1979) (275)
Cell–matrix adhesion in vascular development (2007) (270)
Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters (2014) (269)
Effects of LETS glycoprotein on cell motility (1978) (260)
Absence of P-selectin delays fatty streak formation in mice. (1997) (255)
Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site. (1996) (253)
GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis. (2006) (251)
Fibronectin and Its Relation to Cellular Structure and Behavior (1981) (246)
Mouse primordial germ cells lacking beta1 integrins enter the germline but fail to migrate normally to the gonads. (1999) (239)
Surface distribution of LETS protein in relation to the cytoskeleton of normal and transformed cells (1977) (238)
Lymphatic or Hematogenous Dissemination: How Does a Metastatic Tumor Cell Decide? (2006) (237)
Selective ablation of αv integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death (2004) (237)
The evolution of metazoan extracellular matrix (2012) (233)
Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment. (1999) (230)
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils (2017) (229)
Density and cell cycle dependence of cell surface proteins in hamster fibroblasts. (1974) (228)
Alpha4 integrins regulate the proliferation/differentiation balance of multilineage hematopoietic progenitors in vivo. (1999) (228)
Fibronectins in vascular morphogenesis (2009) (227)
Temporal and spatial regulation of fibronectin in early Xenopus development (1984) (224)
Gene Expression Changes in an Animal Melanoma Model Correlate with Aggressiveness of Human Melanoma Metastases (2008) (224)
Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo. (1989) (224)
Plasma fibronectin promotes thrombus growth and stability in injured arterioles (2003) (223)
Novel Roles for α3β1 Integrin as a Regulator of Cytoskeletal Assembly and as a Trans-dominant Inhibitor of Integrin Receptor Function in Mouse Keratinocytes (1998) (221)
GPR56 Regulates Pial Basement Membrane Integrity and Cortical Lamination (2008) (220)
Interaction of fibronectin with its receptor on platelets (1985) (220)
Extrajunctional distribution of N-cadherin in cultured human endothelial cells. (1992) (219)
Immunocytochemical localization of fibronectin in embryonic chick trunk and area vasculosa. (1981) (218)
Mesodermal defects and cranial neural crest apoptosis in alpha5 integrin-null embryos. (1997) (216)
Defects in hemostasis in P-selectin-deficient mice. (1996) (209)
Platelet-endothelial interactions in inflamed mesenteric venules. (1998) (206)
Ulcerative colitis and autoimmunity induced by loss of myeloid αv integrins (2007) (201)
Expression of normal and mutant avian integrin subunits in rodent cells [published erratum appears in J Cell Biol 1989 Oct;109(4 Pt 1):1187] (1989) (199)
Interaction of Dendritic Cells with Skin Endothelium: A New Perspective on Immunosurveillance (1999) (194)
Role of surface alterations in cell transformation: the importance of proteases and surface proteins (1974) (193)
Integrins in vascular development. (1999) (184)
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver (2014) (183)
Mesodermal development in mouse embryos mutant for fibronectin (1996) (181)
Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells (2019) (178)
Ras Activation Is Necessary for Integrin-mediated Activation of Extracellular Signal-regulated Kinase 2 and Cytosolic Phospholipase A2 but Not for Cytoskeletal Organization* (1996) (177)
The emergence of integrins: a personal and historical perspective. (2004) (177)
Defective Associations between Blood Vessels and Brain Parenchyma Lead to Cerebral Hemorrhage in Mice Lacking αv Integrins (2002) (174)
Cellular and subcellular localization of lets protein in the nervous system (1978) (174)
Alternative splicing of chicken fibronectin in embryos and in normal and transformed cells (1987) (174)
Guidelines for human embryonic stem cell research (2005) (173)
Fibronectin localization in the rat glomerulus (1980) (170)
Distribution of fibronectin in the ectoderm of gastrulating chick embryos (1979) (169)
Overlapping and independent functions of fibronectin receptor integrins in early mesodermal development. (1999) (169)
Metastatic Potential Generic Predisposition of the Primary Tumor or Rare, Metastatic Variants—Or Both? (2003) (168)
Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element. (1994) (168)
In vivo genome editing and organoid transplantation models of colorectal cancer (2017) (168)
A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis (2012) (167)
The echinoderm adhesome. (2006) (167)
A novel alpha integrin subunit associates with betaPS and functions in tissue morphogenesis and movement during Drosophila development. (1997) (162)
Analysis of platelet adhesion with a radioactive chemical crosslinking reagent: Interaction of thrombospondin with fibronectin and collagen (1982) (161)
Embryonic mesodermal defects in 5 integrin-deﬁcient mice (1996) (161)
Nanobody-based CAR T cells that target the tumor microenvironment inhibit the growth of solid tumors in immunocompetent mice (2019) (159)
The dynamic dialogue between cells and matrices: implications of fibronectin's elasticity. (1999) (158)
alpha 3A beta 1 integrin localizes to focal contacts in response to diverse extracellular matrix proteins. (1995) (158)
Tumor-secreted vascular endothelial growth factor-C is necessary for prostate cancer lymphangiogenesis, but lymphangiogenesis is unnecessary for lymph node metastasis. (2005) (157)
Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice (1995) (155)
Primordial germ cells of Xenopus embryos: The role of fibronectin in their adhesion during migration (1981) (152)
In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. (2013) (152)
Integrin heterodimer and receptor complexity in avian and mammalian cells (1989) (151)
Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics. (2017) (151)
Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression. (2016) (149)
Broad spectrum pan-cadherin antibodies, reactive with the C-terminal 24 amino acid residues of N-cadherin. (1990) (147)
Cell-type-specific fibronectin subunits generated by alternative splicing. (1986) (147)
Astrocytes in culture synthesize and secrete a variant form of fibronectin (1985) (145)
Drosophila syndecan: conservation of a cell-surface heparan sulfate proteoglycan. (1994) (144)
Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins. (1996) (144)
Endothelial α5 and αv integrins cooperate in remodeling of the vasculature during development (2010) (143)
Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins. (2007) (143)
Fibronectin regulates assembly of actin filaments and focal contacts in cultured cells via the heparin-binding site in repeat III13. (1999) (143)
Patterns of fibronectin gene expression and splicing during cell migration in chicken embryos. (1988) (142)
Layilin, A Novel Talin-binding Transmembrane Protein Homologous with C-type Lectins, is Localized in Membrane Ruffles (1998) (142)
Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins. (1996) (142)
A single rat fibronectin gene generates three different mRNAs by alternative splicing of a complex exon. (1984) (141)
Fibronectin binds to some bacteria but does not promote their uptake by phagocytic cells. (1983) (141)
An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin [see comments] (1989) (140)
Blood cell dynamics in P-selectin-deficient mice. (1995) (139)
The diverse roles of integrins and their ligands in angiogenesis. (2002) (139)
A LARGE GLYCOPROTEIN LOST FROM THE SURFACES OF TRANSFORMED CELLS * (1978) (137)
Hemostasis in the Mouse (Mus musculus): A Review (1999) (137)
Mapping of the functional determinants of the integrin beta 1 cytoplasmic domain by site-directed mutagenesis. (1990) (137)
Layilin, a novel integral membrane protein, is a hyaluronan receptor. (2001) (137)
Extensive disulfide bonding at the mammalian cell surface. (1977) (135)
Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin. (2007) (133)
Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1. (1990) (131)
Dystrophic Muscle in Mice Chimeric for Expression of α5 Integrin (1998) (127)
Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice. (2001) (126)
Extracellular matrix proteins in hemostasis and thrombosis. (2012) (125)
Residues SFQ (173-175) in the large extracellular loop of CD9 are required for gamete fusion. (2002) (124)
Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis (2011) (123)
Mesoderm induction and the control of gastrulation in Xenopus laevis: the roles of fibronectin and integrins. (1990) (120)
Role of endothelial selectins in wound repair. (1997) (116)
Phagocytosis of gelatin-latex particles by a murine macrophage line is dependent on fibronectin and heparin (1981) (116)
Organization of the fibronectin gene provides evidence for exon shuffling during evolution. (1987) (116)
Elucidation of the Roles of Tumor Integrin β1 in the Extravasation Stage of the Metastasis Cascade. (2016) (115)
Xenopus laevis integrins. Structural conservation and evolutionary divergence of integrin beta subunits. (1988) (115)
Requirement for the NF-κB Family Member RelA in the Development of Secondary Lymphoid Organs (2002) (115)
Requirements for integrins during Drosophila development. (1990) (114)
Effects of cytochalasin B and colchicine on attachment of a major surface protein of fibroblasts. (1977) (112)
Role of P-Selectin Cytoplasmic Domain in Granular Targeting In Vivo and in Early Inflammatory Responses (1998) (112)
Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation (2018) (109)
A difference between plasma and cellular fibronectins located with monoclonal antibodies (1981) (107)
Comprehensive proteomic characterization of stem cell-derived extracellular matrices. (2017) (107)
alpha3beta1 and alpha6beta4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development. (2000) (106)
Deformability of Tumor Cells versus Blood Cells (2015) (106)
A Quantitative System for Studying Metastasis Using Transparent Zebrafish. (2015) (106)
SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis (2018) (103)
Alterations in surface proteins in chicken cells transformed by temperature-sensitive mutants of Rous sarcoma virus. (1975) (103)
GPR56 Regulates VEGF production and angiogenesis during melanoma progression. (2011) (102)
Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival (2017) (102)
Fibrinogen and von Willebrand factor‐independent platelet aggregation in vitro and in vivo (2006) (101)
Biosynthesis and processing of fibronectin in NIL.8 hamster cells. (1979) (101)
Differential requirements for alpha4 integrins during fetal and adult hematopoiesis. (1996) (100)
Accelerated re-epithelialization in β3-integrin-deficient- mice is associated with enhanced TGF-β1 signaling (2005) (100)
Increased primary tumor growth in mice null for β3- or β3/β5-integrins or selectins (2004) (99)
Direct Test of Potential Roles of EIIIA and EIIIB Alternatively Spliced Segments of Fibronectin in Physiological and Tumor Angiogenesis (2004) (98)
An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin. (1989) (98)
A novel, tissue-specific integrin subunit, beta nu, expressed in the midgut of Drosophila melanogaster. (1993) (95)
Acute passive anti-glomerular basement membrane nephritis in P-selectin-deficient mice. (1996) (94)
Surface proteins and fibrinolytic activity of cultured mammalian cells. (1976) (93)
CUB-domain–containing protein 1 (CDCP1) activates Src to promote melanoma metastasis (2011) (93)
Fibronectin isoform distribution in the mouse. I. The alternatively spliced EIIIB, EIIIA, and V segments show widespread codistribution in the developing mouse embryo. (1996) (92)
αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice. (2010) (91)
The spatial and temporal expression patterns of integrin α9β1 and one of its ligands, the EIIIA segment of fibronectin, in cutaneous wound healing (2004) (90)
Retroviral expression of alternatively spliced forms of rat fibronectin (1990) (89)
Reduced blood vessel formation and tumor growth in alpha5-integrin-negative teratocarcinomas and embryoid bodies. (2001) (89)
Identification of the Peptide Sequences within the EIIIA (EDA) Segment of Fibronectin That Mediate Integrin α9β1-dependent Cellular Activities* (2008) (89)
Viral transformation of rat myoblasts: effects on fusion and surface properties. (1976) (89)
Noninvasive imaging of tumor progression, metastasis, and fibrosis using a nanobody targeting the extracellular matrix (2019) (88)
Enrichment of Extracellular Matrix Proteins from Tissues and Digestion into Peptides for Mass Spectrometry Analysis (2015) (88)
A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy. (2006) (87)
Fusion Competence of Myoblasts Rendered Genetically Null for N-Cadherin in Culture (1997) (87)
Drosophila PS1 integrin is a laminin receptor and differs in ligand specificity from PS2. (1994) (85)
Fibronectin binds to the C1q component of complement. (1982) (85)
Towards definition of an ECM parts list: an advance on GO categories. (2012) (82)
Similarities and differences between the fibronectins of normal and transformed hamster cells. (1981) (81)
Genetic analysis of alpha 4 integrin functions in the development of mouse skeletal muscle (1996) (79)
Migration of neuroblasts along preexisting axonal tracts during prenatal cerebellar development (1986) (79)
Domain structure of fibronectin and its relation to function. Disulfides and sulfhydryl groups. (1979) (77)
Multiple fibronectin subunits and their post-translational modifications. (1984) (77)
Analyses of PS integrin functions during Drosophila development. (1993) (76)
Cell surface fibronectin and oncogenic transformation. (1979) (76)
In Vivo Roles of Integrins During Leukocyte Development and Traffic: Insights from the Analysis of Mice Chimeric for α5, αv, and α4 Integrins1 (2000) (76)
Therapeutic expression of the platelet-specific integrin, αIIbβ3, in a murine model for Glanzmann thrombasthenia (2005) (76)
Characterization of a novel adhesion function blocking monoclonal antibody to rat/mouse P-selectin generated in the P-selectin-deficient mouse. (1997) (75)
On the origin of species of fibronectin. (1985) (75)
Macrophage-Secreted TNFα and TGFβ1 Influence Migration Speed and Persistence of Cancer Cells in 3D Tissue Culture via Independent Pathways. (2016) (74)
Topological arrangement of the major structural features of fibronectin. (1980) (72)
Mouse keratinocytes immortalized with large T antigen acquire alpha3beta1 integrin-dependent secretion of MMP-9/gelatinase B. (2000) (72)
Stretching the boundaries of extracellular matrix research (2014) (72)
Elements regulating an alternatively spliced exon of the rat fibronectin gene (1993) (72)
Drosophila integrins and their ligands. (1994) (72)
Accelerated re-epithelialization in beta3-integrin-deficient- mice is associated with enhanced TGF-beta1 signaling. (2005) (72)
Targeted Mutations in Integrins and their Ligands: Their Implications for Vascular Biology (1997) (71)
Overlapping functions of E- and P-selectin in neutrophil recruitment during acute inflammation. (1998) (71)
PF4 Promotes Platelet Production and Lung Cancer Growth. (2016) (70)
Identification and characterization of alternatively spliced fibronectin mRNAs expressed in early Xenopus embryos. (1992) (70)
Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE (2016) (70)
A method for separating cells from early sea urchin embryos. (1970) (70)
The cytoskeletal protein talin contains at least two distinct vinculin binding domains (1993) (70)
Repeating modular structure of the fibronectin gene: relationship to protein structure and subunit variation. (1985) (69)
Fibronectin isoform distribution in the mouse. II. Differential distribution of the alternatively spliced EIIIB, EIIIA, and V segments in the adult mouse. (1996) (69)
An angiogenic role for the α5β1 integrin in promoting endothelial cell proliferation during cerebral hypoxia (2012) (69)
GPR56 and TG2: Possible Roles in Suppression of Tumor Growth by the Microenvironment (2007) (67)
Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma (2020) (66)
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression (2017) (66)
CHARACTERIZATION OF THE EXTERNAL PROTEINS OF HAMSTER FIBROBLASTS (1974) (66)
Engulfing tumors with synthetic extracellular matrices for cancer immunotherapy. (2009) (65)
Protein 4.1B suppresses prostate cancer progression and metastasis (2007) (65)
Decreased Plasma Fibronectin Leads to Delayed Thrombus Growth in Injured Arterioles (2006) (64)
A system for Cre-regulated RNA interference in vivo (2008) (64)
The Complexity of Platelet Adhesion to Extracellular Matrices (1991) (63)
Proteomic characterization of human multiple myeloma bone marrow extracellular matrix (2017) (63)
A Whole-Genome Assembly of Drosophila (2000) (63)
Integrin receptors are required for cell survival and proliferation during development of the peripheral glial lineage. (2001) (62)
Control of alternative pre-mRNA splicing by distributed pentameric repeats. (1997) (62)
A chimeric N-cadherin/beta 1-integrin receptor which localizes to both cell-cell and cell-matrix adhesions. (1992) (61)
α4β1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development (2007) (61)
The location of proteins labeled by the 125I-lactoperoxidase system in the NIL 8 hamster fibroblast (1975) (60)
Relationships between microfilaments, cell-substratum adhesion, and fibronectin. (1982) (57)
Genetic analyses of cell-matrix interactions in development. (1994) (56)
Genetic manipulation of vascular adhesion molecules in mice. (1996) (56)
Expression of α4 Integrin mRNA and Protein and Fibronectin in the Early Chicken Embryo (1994) (56)
α4β1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development (2007) (55)
Surfaces of normal and malignant cells (1979) (55)
Structure-function analysis reveals discrete beta3 integrin inside-out and outside-in signaling pathways in platelets. (2007) (55)
Specificity of cell adhesion in development: the cadherin superfamily. (1992) (55)
Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis. (2003) (54)
Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner (2011) (54)
Increased primary tumor growth in mice null for beta3- or beta3/beta5-integrins or selectins. (2004) (54)
Rolling in P-selectin-deficient mice is reduced but not eliminated in the dorsal skin. (1995) (54)
Analyses of the role of endogenous SPARC in mouse models of prostate and breast cancer (2007) (53)
Expression of the alternatively spliced EIIIB segment of fibronectin. (1995) (53)
Identification of the peptide sequences within the EIIIA (EDA) segment of fibronectin that mediate integrin alpha9beta1-dependent cellular activities. (2008) (52)
Layilin, a cell surface hyaluronan receptor, interacts with merlin and radixin. (2005) (51)
Proteomic Profiling of the ECM of Xenograft Breast Cancer Metastases in Different Organs Reveals Distinct Metastatic Niches (2020) (51)
Expression of DFak56, a Drosophila homolog of vertebrate focal adhesion kinase, supports a role in cell migration in vivo. (1999) (49)
Extracellular matrix biology (2012) (48)
αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells (2016) (47)
Generation and characterization of a novel adhesion function blocking monoclonal antibody recognizing both rat and mouse E-selectin. (1997) (47)
Developmentally regulated cell surface alterations in Dictyostelium discoideum (1974) (47)
Efficient and stable expression of recombinant fibronectin polypeptides. (1987) (46)
Infection-mediated early-onset periodontal disease in P/E-selectin-deficient mice. (2001) (46)
Essential roles of fibronectin in the development of the left-right embryonic body plan. (2011) (45)
A Direct Test of Potential Roles for β3 and β5 Integrins in Growth and Metastasis of Murine Mammary Carcinomas (2005) (44)
An interaction between αvβ8 integrin and Band 4.1B via a highly conserved region of the Band 4.1 C-terminal domain (2005) (44)
Alternative Splicing of Endothelial Fibronectin Is Induced by Disturbed Hemodynamics and Protects Against Hemorrhage of the Vessel Wall (2014) (44)
The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy. (2017) (43)
Role of disulfide bonds in the attachment and function of large, external, transformation-sensitive glycoprotein at the cell surface. (1978) (43)
Therapeutic expression of the platelet-specific integrin, alphaIIbbeta3, in a murine model for Glanzmann thrombasthenia. (2005) (42)
α3Aβ1 integrin localizes to focal contacts in response to diverse extracellular matrix proteins (1995) (42)
Involvement of fibronectin, Von Willebrand factor, and fibrinogen in platelet interaction with solid substrata. (1981) (42)
Integrin α5β1 is necessary for regulation of radial migration of cortical neurons during mouse brain development (2010) (42)
Endothelium-derived fibronectin regulates neonatal vascular morphogenesis in an autocrine fashion (2017) (41)
Central Roles of &agr;5&bgr;1 Integrin and Fibronectin in Vascular Development in Mouse Embryos and Embryoid Bodies (2002) (41)
Tumour suppressor genes and angiogenesis: the role of TP53 in fibroblasts. (1996) (41)
C3 component of complement secreted by established cell lines (1978) (41)
Cell surface and metabolic labelling of the proteins of normal and transformed chicken cells. (1976) (41)
Analysis of repeated motifs in the talin rod. (1994) (41)
The impact of molecular biology on models for cell adhesion. (1994) (40)
Phosphorylation of vinculin by pp60src: What might it mean? (1982) (39)
α3β1 and α6β4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development (2000) (38)
Tumor Angiogenesis in the Absence of Fibronectin or Its Cognate Integrin Receptors (2015) (38)
Integrin-α5β1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation. (2014) (38)
Structure of Fibronectins (1990) (38)
In vivo roles of integrins during leukocyte development and traffic: insights from the analysis of mice chimeric for alpha 5, alpha v, and alpha 4 integrins. (2000) (38)
Integrin alpha 5 beta 1 is necessary for regulation of radial migration of cortical neurons during mouse brain development (2010) (37)
A Test of the Role of α5 Integrin/Fibronectin Interactions in Tumorigenesis (1998) (35)
Differences in the sulfated macromolecules synthesized by normal and transformed hamster fibroblasts. (1978) (34)
The spatial and temporal expression patterns of integrin alpha9beta1 and one of its ligands, the EIIIA segment of fibronectin, in cutaneous wound healing. (2004) (34)
Cellular location of viral transforming proteins (1980) (34)
α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo (2015) (34)
Sea Urchin Embryos Are Permeable to Actinomycin (1971) (34)
The integrin family of cell surface receptors. (1987) (33)
Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses (2017) (33)
In vitro splicing of fibronectin pre-mRNAs. (1990) (33)
The Lack of ADAM17 Activity during Embryonic Development Causes Hemorrhage and Impairs Vessel Formation (2010) (31)
A direct test of potential roles for beta3 and beta5 integrins in growth and metastasis of murine mammary carcinomas. (2005) (31)
Insights and Questions Arising from Studies of a Mouse Model of Glanzmann Thrombasthenia (1999) (31)
GPR 56 , an atypical G protein-coupled receptor , binds tissue transglutaminase , TG 2 , and inhibits melanoma tumor growth and metastasis (2006) (30)
GPR56 Plays varying roles in endogenous cancer progression (2010) (30)
sevenless: Seven found? (1990) (30)
Embryonic fibronectin isoforms are synthesized in crescents in experimental autoimmune glomerulonephritis. (1995) (29)
Transformation-specific secreted phosphoproteins (1980) (29)
Spatial organization at the cell surface. (1976) (28)
Angiogenesis in P‐ and E‐Selectin‐Deficient Mice (1998) (28)
Corrigendum: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis (2017) (28)
Toward a genetic analysis of cell-matrix adhesion. (1992) (28)
Intravital imaging of metastasis in adult Zebrafish (2017) (28)
Synthesis, secretion, and attachment of LETS glycoprotein in normal and transformed cells. (1977) (27)
Activation of Latent TGF-β1 by Thrombospondin-1 is a Major Component of Wound Repair. (2005) (27)
Genetic ablation of alphav integrins in epithelial cells of the eyelid skin and conjunctiva leads to squamous cell carcinoma. (2008) (26)
Heart development in fibronectin-null mice is governed by a genetic modifier on chromosome four (2007) (26)
Functions of the cytoplasmic domain of the beta PS integrin subunit during Drosophila development. (1994) (26)
An interaction between {alpha}v{beta}8 integrin and Band 4.1B via a highly conserved region of the Band 4.1 C-terminal domain. (2005) (25)
Structural organization of the thrombospondin molecule. (1987) (25)
1997 keystone symposium on signal transduction by cell adhesion receptors. (1997) (25)
Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells (2021) (25)
Properties of the three cell types in sixteen-cell sea urchin embryos: aggregation and microtuble protein synthesis. (1972) (25)
Abstract B38: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis (2018) (24)
Fibronectins: a family of complex and versatile adhesive glycoproteins derived from a single gene. (1985) (24)
Complex regulation of fibronectin synthesis by cells in culture. (1983) (24)
Mapping of the functional determinants of the integrin *, cytoplasmic domain by site-directed mutagenesis (22)
The cloning, genomic organization and expression of the focal contact protein paxillin in Drosophila. (2001) (22)
Mouse keratinocytes immortalized with large T antigen acquire α 3 β 1 integrin-dependent secretion of MMP-9 / gelatinase B (2000) (22)
A novel α integrin subunit associates with β PS and functions in tissue morphogenesis and movement during Drosophila development (1997) (22)
Genetic manipulation of vascular adhesion molecules in mice. (1997) (22)
Properties of the three cell types in sixteen-cell sea urchin embryos: RNA synthesis. (1972) (21)
Natural killer cells require selectins for suppression of subcutaneous tumors. (2009) (21)
Changing Partners (2003) (21)
Research article - The genome of the sea urchin Strongylocentrotus purpuratus (2006) (21)
Proteolytic enzymes in normal and transformed cells. (1979) (21)
Investigations of the possible role of proteases in altering surface proteins of virally transformed hamster fibroblasts. (1976) (20)
Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow (2018) (20)
Gene targeting and generation of mutant mice for studies of cell-extracellular matrix interactions. (1994) (20)
Nephronectin is Correlated with Poor Prognosis in Breast Cancer and Promotes Metastasis via its Integrin-Binding Motifs (2018) (20)
Antibodies and methods for immunohistochemistry of extracellular matrix proteins. (2018) (20)
Expression and localisation of αv integrins in human odontoblasts (2006) (20)
Specifity of cell adhesion in development: the cadherin superfamily (1992) (19)
A test of the role of alpha5 integrin/fibronectin interactions in tumorigenesis. (1998) (19)
Interactions of Fibronectins (1990) (17)
P- and E-selectins are required for the leukocyte recruitment, but not the tissue swelling, associated with IgE- and mast cell-dependent inflammation in mouse skin. (1998) (17)
Characteristics of concanavalin A‐resistant Chinese hamster ovary cells and certain revertants (1979) (17)
β3 Integrins Regulate Lymphocyte Migration and Cytokine Responses in Heart Transplant Rejection (2007) (17)
Isolation and analysis of cDNA and genomic clones of fibronectin and its receptor. (1987) (16)
Fibronectin-coated beads are endocytosed by cells and align with microfilament bundles. (1982) (16)
&agr;5 and &agr;v integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo (2015) (16)
Toward Responsible Human Genome Editing. (2017) (16)
Metastatic cells will take any help they can get. (2011) (16)
Determination of 35 cell surface antigen levels in malignant pleural effusions identifies CD24 as a marker of disseminated tumor cells (2013) (16)
CELL SURFACE COAT OF HAMSTER FIBROBLASTS (1978) (15)
Maximizing response to intratumoral immunotherapy in mice by tuning local retention (2022) (15)
Plasma levels of fibronectin bearing the alternatively spliced EIIIB segment are increased after major trauma. (2003) (15)
A novel , tissue-specific integrin subunit , expressed in the midgut of Drosophila melanogaster Gene (14)
Fibronectin interacts with Clq, a subcomponent of the first component of complement. (1982) (14)
Fibronectin: a versatile gene for a versatile protein. (1984) (14)
Importance of donor- and recipient-derived selectins in cardiac allograft rejection. (2007) (14)
Expression of alpha 4 integrin mRNA and protein and fibronectin in the early chicken embryo. (1994) (13)
Effects of cocultivation with transformed cells on surface proteins of normal cells. (1978) (13)
Wound Healing, Inflammation, and Fibrosis (1990) (13)
Characterization of HeLa nuclear factors which interact with a conditionally processed rat fibronectin pre-mRNA. (1993) (13)
Informational RNA sequences in early sea urchin embryos. (1972) (12)
Introduction and Historical Overview (1990) (12)
Tumor–lymphatic interactions in an activated stromal microenvironment (2007) (12)
Cellular Adhesion and Cell Surface Receptors (1990) (12)
Structural biology. Changing partners. (2003) (12)
Expression and localisation of alphav integrins in human odontoblasts. (2006) (12)
Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing. (2020) (11)
LETS glycoprotein: arrangement and function at the cell surface. (1978) (11)
Functional Comparison of the α3A and α3B Cytoplasmic Domain Variants of the Chicken α3 Integrin Subunit (2001) (10)
correction: Genomic analysis of metastasis reveals an essential role for RhoC (2001) (10)
Evolution The evolution of metazoan extracellular matrix (2012) (10)
Significance of Abnormal Rabbit Ileal Histology in the Pathogenesis of Diarrhea (1979) (9)
Stem cells: US policies on human embryonic stem cells (2008) (9)
Reduced Blood Vessel Formation and Tumor Growth in a 5-Integrin-negative Teratocarcinomas and Embryoid Bodies 1 Daniela Taverna (2001) (9)
The role of fibronectin in cellular behavior. (1980) (9)
Review article: HCV ? STAT-C era of therapy (2010) (8)
YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation (2020) (8)
Structural analysis of fibronectin with monoclonal antibodies. (1981) (7)
The immunoglobulin superfamily in Caenorhabditis elegans and Drosophila melanogaster (2004) (7)
Double knockout highlights value of endothelial selectins. (1996) (7)
Alternative Splicing of FN (Fibronectin) Regulates the Composition of the Arterial Wall Under Low Flow (2020) (7)
Methods for Identification of Fibronectins (1990) (7)
E and P selectins are not required for resistance to severe murine lyme arthritis. (1998) (7)
Distribution of Fibronectins in Vivo (1990) (7)
Transformation-specific secreted proteins. (1980) (7)
Dissemination Tumor Cell Interactions during Hematogenous - HostInitial Hours of Metastasis: The Importance of Cooperative (2012) (7)
Author response: Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters (2014) (6)
The scaffold protein IQGAP1 is crucial for extravasation and metastasis (2020) (6)
Knockout of the gene encoding the extracellular matrix protein Sned1 results in craniofacial malformations and early neonatal lethality (2018) (6)
Agrin in the Muscularis Mucosa Serves as a Biomarker Distinguishing Hyperplastic Polyps from Sessile Serrated Lesions (2019) (6)
Expression of Fibronectins by Cells in Culture (1990) (6)
Isolation and characterization of a cell-surface fraction from hamster-embryo fibroblasts. (1975) (5)
Analysis of Mice Chimeric for Development and Traffic : Insights from the In Vivo Roles of Integrins During Leukocyte (2000) (5)
Review Integrins: Bidirectional, Allosteric Signaling Machines (2002) (5)
Interactions of Fibronectin with Clq, a Subcomponent of the First Component of Complement (1981) (5)
Knockout of the gene encoding the extracellular matrix protein SNED1 results in early neonatal lethality and craniofacial malformations (2020) (5)
Growth and Metastasis of Murine Mammary Carcinomas 5 Integrins in β 3 and β A Direct Test of Potential Roles for Updated (2005) (4)
Functional comparison of the alpha3A and alpha3B cytoplasmic domain variants of the chicken alpha3 integrin subunit. (2001) (4)
Fibronectin binds to the Clq component of complement (2003) (4)
αV integrins in Schwann cells promote attachment to axons, but are dispensable in vivo (2020) (4)
Correction for Xie et al., Nanobody-based CAR T cells that target the tumor microenvironment inhibit the growth of solid tumors in immunocompetent mice (2019) (4)
Fibronectin and the Cytoskeleton (1990) (3)
In Vivo RNA Interference Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling (2011) (3)
Hemostasis and Thrombosis (1990) (2)
Reflections on Integrins-Past, Present, and Future: The Albert Lasker Basic Medical Research Award. (2022) (2)
Endothelial Biomedicine: Endothelial Cell Integrins (2007) (2)
The cell surface (1992) (2)
Interaction of fibronectin with C1q (1982) (2)
Basic and clinical research on angiogenesis (1996) (2)
Cell adhesion and human disease. Chairman's introduction. (1995) (2)
Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology (2012) (2)
Fibronectin synthesis by migrating primordial germ cells (1980) (2)
E and P Selectins Are Not Required for Resistance to Severe Murine Lyme Arthritis (1998) (2)
Evolving policy with science (2017) (2)
Biosynthesis and Fibrillogenesis (1990) (1)
Tumorigenesis and Neoplastic Progression Genetic Ablation of ! v Integrins in Epithelial Cells of the Eyelid Skin and Conjunctiva Leads to Squamous Cell Carcinoma (2008) (1)
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver (2014) (1)
Tumor cell surfaces and malignancy : proceedings of the ICN-UCLA symposium held at Keystone, Colorado, March 18-March 23, 1979 (1980) (1)
thrombocytopenia: response to intravenous IgG therapy A novel murine model of fetal and neonatal alloimmune (2008) (1)
Are Dispensable for Initial Specification of Precursor Cells Fibronectins Are Essential for Heart and Blood Vessel Morphogenesis But (2013) (1)
Correction for Jailkhani et al., Noninvasive imaging of tumor progression, metastasis, and fibrosis using a nanobody targeting the extracellular matrix (2019) (1)
Intratumoral nanobody–IL-2 fusions that bind the tumor extracellular matrix suppress solid tumor growth in mice (2022) (1)
Conditional deletion of alpha (v) integrins causes inflammatory bowel disease. (2005) (1)
Abstract 5004: Profiling the extracellular matrix landscape of tumor microenvironments using proteomics (2018) (1)
Phagocytosis and Interactions with Pathogenic Microorganisms (1990) (1)
Leaders in cell adhesion: an interview with Richard Hynes, pioneer of cell-matrix interactions. Interview by Pamela Cowin. (2013) (1)
A framework for advancing our understanding of cancer-associated fibroblasts (2020) (1)
Abstract 4855: Proteomic characterization of the extracellular matrix in multiple myeloma (2014) (1)
Fibronectin Mutations in Mice (1993) (1)
Abstract 306: Role of tumor beta-1 integrin in the tumor cell extravasation cascade (2015) (1)
outside-in signaling pathways in platelets 3 integrin inside-out and β Structure-function analysis reveals discrete (2013) (1)
Reply to 'UK set to reverse stance on research with chimeras' (2007) (1)
Abstract (2007) (0)
Angiogenesis Fibronectin in Physiological and Tumor EIIIB Alternatively Spliced Segments of Direct Test of Potential Roles of EIIIA and (2004) (0)
Lymphangiogenesis Is Unnecessary for Lymph Node Necessary for Prostate Cancer Lymphangiogenesis, but Tumor-Secreted Vascular Endothelial Growth Factor-C Is (2005) (0)
Integrins Signal Lipid SecondMessengers Required (1995) (0)
LOCALIZATION OF A HEPARIN BINDING SITE OF FIBRONECTIN WITH THE AID OF MONOCLONAL ANTIBODIES (1982) (0)
Abstract 1819: Profiling of extracellular matrix proteins in pancreatic ductal adenocarcinoma progression and metastasis (2015) (0)
Molecular Cloning andFunctional Characterization ofChickLensFiber Connexin 45.6 (1994) (0)
Proteomic Characterization of the Multiple Myeloma Bone Marrow Extracellular Matrix (2014) (0)
The scaffold protein IQGAP1 is crucial for extravasation and metastasis (2020) (0)
Agrin loss in Barrett's esophagus-related neoplasia and its utility as a diagnostic and predictive biomarker. (2021) (0)
Platelets, Tumor Cell Invasiveness, and Metastasis (2013) (0)
Quick Guide to Equations and Assumptions Estimating metastasis initiating cell ( MIC ) frequency (2015) (0)
Abstracts from the EACR seed and soil: in vivo models of metastasis conference (2018) (0)
Proteomic profiling of extracellular matrix components from patient metastases identifies consistently elevated proteins for developing nanobodies that target primary tumors and metastases. (2023) (0)
Cover Image, Volume 69, Issue 1 (2020) (0)
Abstract SY28-01: Multiple changes in tumor extracellular matrices (2012) (0)
Evaluating The Role Of b3‐Integrins In Angiogenesis (2006) (0)
Dystrophic Muscle in Mice Chimeric for Expression of (cid:97) 5 Integrin (1998) (0)
outside-in signaling pathways in platelets Structure-function analysis reveals discrete ß3 integrin inside-out and (2010) (0)
440 Screening of Surface Markers Revealed That CD24 is Overexpressed in Malignant Pleural Effusions and is Required for Xenograft Tumor Formation (2012) (0)
Abstract 2973: Adhesion of tumor cells to ECM microarrays identifies novel ECM interactions in metastasis (2012) (0)
Intravital imaging of metastasis in adult Zebrafish (2017) (0)
Maximizing response to intratumoral immunotherapy in mice by tuning local retention (2022) (0)
Abstract PR15: Haptotaxis and direct remodeling of the extracellular matrix by tumor cells is important for metastasis (2016) (0)
Development and Differentiation (1990) (0)
Cartilage Matrix Protein FormsaTypeII Collagen-independent Filamentous Network: Analysis inPrimary CellCultures withaRetrovirus Expression System (1995) (0)
A Novel Mouse Model to Study the Pathogenesis of Eyelid Squamous Cell Carcinoma (2007) (0)
Deformability of Tumor Cells versus Blood Cells how this access benefits you. Your story matters (2015) (0)
ARY adhesion events mediated by α 4 integrins are essen iac development (1995) (0)
Extracellular Matrix Biomarkers for Diagnosis, Prognosis, Imaging, and Targeting (2015) (0)
ROLES OF DONOR-DERIVED SELECTINS IN THE DEVELOPMENT OF BOTH ACUTE REJECTION AND GRAFT ARTERIOSCLEROSIS. (2006) (0)
Constituents and Functions An Inventory of Extracellular Matrix − − Overview of the Matrisome service (2011) (0)
Fibrinogen and von Willebrand Factor-Independent Platelet Aggregation: The Essential Roles of β3 Integrin, Thrombin, and Divalent Ca2+ Cations. (2005) (0)
Implications for Future Research (1990) (0)
GPR56 binds tissue transglutaminase and inhibits melanoma tumor growth and metastasis (2007) (0)
The Whitehead Institute and MIT (1992) (0)
Integrin Binding andCellSpreading onExtracellular Matrix ActatDifferent Points intheCellCycle toPromote Hepatocyte Growth (1994) (0)
TheMembrane-Cytoplasm Interface ofIntegrin a Subunits IsCritical forReceptor Latency (1996) (0)
TABLE I Fibronectin Synthesis In Vitro * Cell type Comments Fibroblasts Endothelial cells Chond rocytes Myoblasts & myotubes Macrophages Hepatocytes Amniotic cells Glial cell lines Intestinal epithelial cells (2003) (0)
relapsing fever borreliosis Spirochete-platelet attachment and thrombocytopenia in murine (2013) (0)
Genetic Ablation of (cid:1) v Integrins in Epithelial Cells of the Eyelid Skin and Conjunctiva Leads to Squamous Cell Carcinoma (2008) (0)
Abstract 549: Alternative Splicing of Fibronectin Regulates Extracellular Matrix Composition of the Inflamed Arterial Wall (2019) (0)
Abstract A45: Understanding the roles of extracellular matrix proteins in pancreatic ductal adenocarcinoma progression and metastasis (2015) (0)
Fibronectins and Embryonic Cell Migration (1992) (0)
Analysis The Evolution of Cell Adhesion J (2000) (0)
Surface Marker Analysis in the Evaluation of Pleural Effusions: Unique Markers Can Assist in Distinguishing Malignant From Nonmalignant Effusions (2010) (0)
Dissemination Tumor Cell Interactions during Hematogenous − Host The Initial Hours of Metastasis : The Importance of Cooperative Updated (2012) (0)
Endothelium-derived fibronectin regulates neonatal vascular morphogenesis in an autocrine fashion (2017) (0)
Interactions Of Platelets With Proteins Of Plasma And Matrices (1981) (0)
Extracellular Matrix Proteins in Hemostasis and Thrombosis service (2011) (0)

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