Richard J Evans
#173,430
Most Influential Person Now
Researcher
Richard J Evans's AcademicInfluence.com Rankings
Richard J Evanshistory Degrees
History
#4962
World Rank
#6841
Historical Rank
Modern History
#58
World Rank
#68
Historical Rank
Download Badge
History
Why Is Richard J Evans Influential?
(Suggest an Edit or Addition)Richard J Evans's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP (1994) (1066)
- ATP mediates fast synaptic transmission in mammalian neurons (1992) (579)
- Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors (2000) (412)
- Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2x purinoceptors). (1995) (334)
- Ionic permeability of, and divalent cation effects on, two ATP‐gated cation channels (P2X receptors) expressed in mammalian cells. (1996) (276)
- Mycobacteria distenct from Mycobacterium avium subsp. paratuberculosis isolated from the faeces of ruminants possess IS900-like sequences detectable IS900 polymerase chain reaction: implications for diagnosis. (1999) (259)
- A Role of the Fast ATP-gated P2X1 Cation Channel in Thrombosis of Small Arteries In Vivo (2003) (222)
- The Role of Positively Charged Amino Acids in ATP Recognition by Human P2X1 Receptors* (2000) (189)
- Molecular properties of P2X receptors (2006) (179)
- Vasoconstriction of guinea‐pig submucosal arterioles following sympathetic nerve stimulation is mediated by the release of ATP (1992) (176)
- P2X receptor expression in mouse urinary bladder and the requirement of P2X1 receptors for functional P2X receptor responses in the mouse urinary bladder smooth muscle (2000) (170)
- ADP is not an agonist at P2X1 receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets (2000) (159)
- Conserved cysteine residues in the extracellular loop of the human P2X(1) receptor form disulfide bonds and are involved in receptor trafficking to the cell surface. (2002) (156)
- Characterization of cultured dorsal root ganglion neuron P2X receptors (1999) (149)
- Characterization of P2‐purinoceptors in the smooth muscle of the rat tail artery: a comparison between contractile and electrophysiological responses (1994) (129)
- Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior. (2003) (125)
- Molecular properties of ATP-gated P2X receptor ion channels. (2004) (122)
- Synaptic P2X receptors (2001) (118)
- ATP Binding at Human P2X1 Receptors (2004) (112)
- P2X(1) receptor-deficient mice establish the native P2X receptor and a P2Y6-like receptor in arteries. (2002) (108)
- P2X1 Ion Channels Promote Neutrophil Chemotaxis through Rho Kinase Activation1 (2009) (101)
- Functional Characterization of a P2X Receptor from Schistosoma mansoni* (2004) (100)
- Disruption of Lipid Rafts Inhibits P2X1 Receptor-mediated Currents and Arterial Vasoconstriction* (2005) (100)
- P2X Receptor Immunoreactivity in Different Arteries from the Femoral, Pulmonary, Cerebral, Coronary and Renal Circulations (2001) (97)
- 2′,3′‐O‐(2,4,6‐ trinitrophenyl) adenosine 5′‐triphosphate (TNP‐ATP)–a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels (1998) (95)
- Inhibition of Platelet Functions and Thrombosis through Selective or Nonselective Inhibition of the Platelet P2 Receptors with Increasing Doses of NF449 [4,4′,4″,4″′-(Carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-disulfonic Acid Octasodium Salt] (2005) (89)
- A study of P2X1 receptor function in murine megakaryocytes and human platelets reveals synergy with P2Y receptors (2002) (87)
- Cyclooxygenase‐1 is a marker for a subpopulation of putative nociceptive neurons in rat dorsal root ganglia (2000) (76)
- Emerging roles for P2X1 receptors in platelet activation (2004) (75)
- Nerve evoked P2X receptor contractions of rat mesenteric arteries; dependence on vessel size and lack of role of L‐type calcium channels and calcium induced calcium release (2001) (74)
- Structural interpretation of P2X receptor mutagenesis studies on drug action (2010) (74)
- P2X receptors in autonomic and sensory neurons (1996) (71)
- G-protein-coupled receptor regulation of P2X1 receptors does not involve direct channel phosphorylation. (2004) (71)
- Lack of run‐down of smooth muscle P2X receptor currents recorded with the amphotericin permeabilized patch technique, physiological and pharmacological characterization of the properties of mesenteric artery P2X receptor ion channels (2000) (71)
- The role of positively charged amino acids in ATP recognition by human P2X(1) receptors. (2000) (70)
- Use of BACTEC radiometric culture method and polymerase chain reaction for the rapid screening of faeces and tissues for Mycobacterium paratuberculosis. (1995) (70)
- Agonist‐stimulated internalisation of the ligand‐gated ion channel P2X1 in rat vas deferens (2001) (69)
- Cysteine Substitution Mutagenesis and the Effects of Methanethiosulfonate Reagents at P2X2 and P2X4 Receptors Support a Core Common Mode of ATP Action at P2X Receptors* (2008) (69)
- Functional Regulation of P2X6 Receptors by N-Linked Glycosylation: Identification of a Novel αβ-Methylene ATP-Sensitive Phenotype (2004) (69)
- Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling. (2005) (66)
- Renal autoregulation in P2X1 knockout mice. (2004) (66)
- Cysteine Substitution Mutants Give Structural Insight and Identify ATP Binding and Activation Sites at P2X Receptors (2007) (65)
- Liver and adipose tissue fatty acid ethyl esters obtained at autopsy are postmortem markers for premortem ethanol intake. (2002) (65)
- Single channel properties of ATP-gated cation channels (P2X receptors) heterologously expressed in Chinese hamster ovary cells (1996) (62)
- P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice. (2014) (62)
- The P2X1 receptor and platelet function (2011) (61)
- Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior (2003) (60)
- Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel (2012) (59)
- P2X1 and P2X4 receptor currents in mouse macrophages (2007) (59)
- Analysis of the Membrane Topology of the Acid-sensing Ion Channel 2a* (2004) (57)
- P2 purinoceptor‐mediated control of rat cerebral (pial) microvasculature; contribution of P2X and P2Y receptors (2000) (57)
- Nerve‐evoked purinergic signalling suppresses action potentials, Ca2+ flashes and contractility evoked by muscarinic receptor activation in mouse urinary bladder smooth muscle (2009) (55)
- P2X(1) receptor subunit contribution to gating revealed by a dominant negative PKC mutant. (2002) (54)
- Orthosteric and allosteric binding sites of P2X receptors (2009) (54)
- Contribution of conserved polar glutamine, asparagine and threonine residues and glycosylation to agonist action at human P2X1 receptors for ATP (2006) (54)
- Direct Voltage Control of Signaling via P2Y1 and Other Gαq-coupled Receptors* (2005) (53)
- Properties of P2X and P2Y receptors are dependent on artery diameter in the rat mesenteric bed (2000) (53)
- Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120 (2017) (51)
- Purinergic 2X1 Receptors Mediate Endothelial Dependent Vasodilation to ATP (2007) (51)
- Lipid Raft Association and Cholesterol Sensitivity of P2X1-4 Receptors for ATP (2010) (50)
- Amplification of human platelet activation by surface pannexin-1 channels (2014) (50)
- Potassium currents and their modulation by muscarine and substance P in neuronal cultures from adult guinea pig celiac ganglia. (1993) (50)
- Transformation of Clostridium perfringens (1984) (50)
- Regulation of Human Recombinant P2X3 Receptors by Ecto-Protein Kinase C (2005) (50)
- Endotoxin-induced platelet aggregation in heparinised equine whole blood in vitro. (1994) (48)
- P2X1 receptors mediate sympathetic postjunctional Ca2+ transients in mesenteric small arteries. (2006) (47)
- Heterogeneity of P2X receptors in sympathetic neurons: contribution of neuronal P2X1 receptors revealed using knockout mice. (2004) (46)
- Morphological properties and projections of electrophysiologically characterized neurons in the guinea-pig submucosal plexus (1994) (46)
- Evidence for P2Y1, P2Y2, P2Y6 and atypical UTP‐sensitive receptors coupled to rises in intracellular calcium in mouse cultured superior cervical ganglion neurons and glia (2004) (46)
- Identification of a P2X1 purinoceptor expressed on human platelets. (1998) (46)
- Naturally-occurring fusidic acid resistance in staphylococci and its linkage to other resistances (1966) (45)
- P2X receptor subtype‐specific modulation of excitatory and inhibitory synaptic inputs in the rat brainstem (2004) (45)
- Cysteine Scanning Mutagenesis (Residues Glu52–Gly96) of the Human P2X1 Receptor for ATP (2011) (44)
- The P2X1 Receptor Is Required for Neutrophil Extravasation during Lipopolysaccharide-Induced Lethal Endotoxemia in Mice (2015) (44)
- Shuttle plasmids for Escherichia coli and Clostridium perfringens (1984) (43)
- Differential sensitivity of human platelet P2X1 and P2Y1 receptors to disruption of lipid rafts. (2006) (41)
- ATP‐gated P2X1 ion channels protect against endotoxemia by dampening neutrophil activation (2012) (41)
- Comparison of P2X receptors in rat mesenteric, basilar and septal (coronary) arteries. (2000) (40)
- The effects of aspirin and paracetamol on the aggregation of equine blood platelets. (1994) (40)
- Male contraception via simultaneous knockout of α1A-adrenoceptors and P2X1-purinoceptors in mice (2013) (40)
- The Intracellular Amino Terminus Plays a Dominant Role in Desensitization of ATP-gated P2X Receptor Ion Channels* (2011) (40)
- ATP-Gated P2X Receptor Channels: Molecular Insights into Functional Roles. (2019) (37)
- The ionogenic nature of the secretory-granule membrane. Electrokinetic properties of isolated chromaffin granules. (1972) (37)
- Effects of diadenosine polyphosphates (ApnAs) and adenosine polyphospho guanosines (ApnGs) on rat mesenteric artery P2X receptor ion channels (2000) (36)
- P2X1, P2X4, and P2X7 Receptor Knock Out Mice Expose Differential Outcome of Sepsis Induced by α-Haemolysin Producing Escherichia coli (2017) (36)
- Smooth muscle does not have a common P2x receptor phenotype: expression, ontogeny and function of P2x1 receptors in mouse ileum, bladder and reproductive systems (2001) (35)
- Contribution of the region Glu181 to Val200 of the extracellular loop of the human P2X1 receptor to agonist binding and gating revealed using cysteine scanning mutagenesis1 (2009) (34)
- P2X1 receptor mobility and trafficking; regulation by receptor insertion and activation (2010) (34)
- Lack of evidence for functional ADP-activated human P2X1 receptors supports a role for ATP during hemostasis and thrombosis. (2003) (34)
- Functional regulation of P2X6 receptors by N-linked glycosylation: identification of a novel alpha beta-methylene ATP-sensitive phenotype. (2004) (33)
- Endogenous activation of adenosine A1 receptors, but not P2X receptors, during high-frequency synaptic transmission at the calyx of Held. (2006) (32)
- Platelet-activating factor and not thromboxane A2 is an important mediator of endotoxin-induced platelet aggregation in equine heparinised whole blood in vitro. (1996) (31)
- Heat Shock Protein 90 Inhibitors Reduce Trafficking of ATP-gated P2X1 Receptors and Human Platelet Responsiveness* (2012) (28)
- Serological response of cattle after vaccination and challenge with Brucella abortus. (1982) (28)
- Conserved negatively charged residues are not required for ATP action at P2X(1) receptors. (2001) (28)
- Application of an enzyme-linked immunosorbent assay in the final stages of a bovine brucellosis eradication program. (1986) (28)
- Contribution of conserved glycine residues to ATP action at human P2X1 receptors: mutagenesis indicates that the glycine at position 250 is important for channel function (2005) (28)
- P 2 X 1 Receptor-Deficient Mice Establish the Native P 2 X Receptor and a P 2 Y 6-Like Receptor in Arteries (2002) (26)
- Identification of Human P2X1 Receptor-interacting Proteins Reveals a Role of the Cytoskeleton in Receptor Regulation* (2011) (25)
- Extracellular Ca2+ modulates ADP-evoked aggregation through altered agonist degradation: implications for conditions used to study P2Y receptor activation (2011) (24)
- Ca2+ Influx through P2X1 Receptors Amplifies P2Y1 Receptor-Evoked Ca2+ Signaling and ADP-Evoked Platelet Aggregation (2014) (23)
- Secholex, Clofibrate and taurine in hyperlipidaemia. (1974) (21)
- Regions of the amino terminus of the P2X1 receptor required for modification by phorbol ester and mGluR1α receptors (2009) (21)
- Contribution of the Juxtatransmembrane Intracellular Regions to the Time Course and Permeation of ATP-gated P2X7 Receptor Ion Channels* (2015) (21)
- Mapping the Allosteric Action of Antagonists A740003 and A438079 Reveals a Role for the Left Flipper in Ligand Sensitivity at P2X7 Receptors (2018) (20)
- Effects of phospholipase A2 inhibitors on coupling of α2‐adrenoceptors to inwardly rectifying potassium currents in guinea‐pig submucosal neurones (1993) (19)
- An evaluation of antibody detection of the P2X1 receptor subunit in the CNS of wild type and P2X1-knockout mice (2006) (19)
- Variable inactivation of human factor VIII from different sources by human factor VIII inhibitors (1991) (17)
- Direct voltage control of signaling via P2Y1 and other Galphaq-coupled receptors. (2005) (17)
- P2X Receptor Chimeras Highlight Roles of the Amino Terminus to Partial Agonist Efficacy, the Carboxyl Terminus to Recovery from Desensitization, and Independent Regulation of Channel Transitions* (2013) (16)
- The role of ADP in endotoxin-induced equine platelet activation. (1996) (16)
- The molecular biology of P2X receptors. (1996) (16)
- Review Article: Blood platelets and their role in the genesis and sequelae of intestinal ischaemia (2010) (16)
- Mapping the Site of Action of Human P2X7 Receptor Antagonists AZ11645373, Brilliant Blue G, KN-62, Calmidazolium, and ZINC58368839 to the Intersubunit Allosteric Pocket (2019) (16)
- Morphological changes in cultured astrocytes following exposure to calcium ionophores (1987) (15)
- Relative contributions of ATP and noradrenaline to the nerve evoked contraction of the rabbit jejunal artery (1992) (15)
- Induced Basal Normoglycemia and Altered Platelet Aggregation in Non-insulin-dependent Diabetes (1982) (15)
- Mapping the binding site of the P2X receptor antagonist PPADS reveals the importance of orthosteric site charge and the cysteine-rich head region (2018) (14)
- Mutagenesis studies of conserved proline residues of human P2X1 receptors for ATP indicate that proline 272 contributes to channel function (2005) (14)
- Mechanistic insights from resolving ligand-dependent kinetics of conformational changes at ATP-gated P2X1R ion channels (2016) (14)
- ADP induces desensitisation of equine platelet aggregation responses: studies using ADP beta S, a stable analogue of ADP. (1993) (14)
- Effects of a P2Y(12) receptor antagonist on the response of equine platelets to ADP. Comparison with human platelets. (2002) (14)
- The effect of challenge with virulent Brucella abortus on beef cattle vaccinated as calves or adults with either Brucella abortus strain 19 or 45/20. (1981) (14)
- A study of P 2 X 1 receptor function in murine megakaryocytes and human platelets reveals synergy with P 2 Y receptors (2002) (13)
- Proceedings: Refractoriness in blood platelets: effect of prior exposure to aggregating agents on subsequent aggregation responses. (1974) (13)
- Platelets enhance endotoxin-induced monocyte tissue factor (TF) activity in the horse. (2004) (13)
- The Residual Nonadrenergic Contractile Response to Nerve Stimulation of the Mouse Prostate Is Mediated by Acetylcholine but Not ATP in a Comparison with the Mouse Vas Deferens (2010) (13)
- Dextran-70 inhibits equine platelet aggregation induced by PAF but not by other agonists. (1998) (13)
- Kinetics of Conformational Changes Revealed by Voltage-Clamp Fluorometry Give Insight to Desensitization at ATP-Gated Human P2X1 Receptors (2014) (12)
- Cloning of PAR3 cDNA from human platelets, and human erythroleukemic and human promonocytic cell lines. (1997) (12)
- Mass spectrometry analysis of human P2X1 receptors; insight into phosphorylation, modelling and conformational changes (2012) (12)
- The effect of selenium supplementation on antibody response to bacterial antigens in merino sheep with a low selenium status. (1990) (11)
- An enzyme-linked immunosorbent assay for the detection of Rathayibacter toxicus, the bacterium involved in annual ryegrass toxicity, in hay (2006) (11)
- ATP in synapses (1993) (11)
- Characterisation of ATP analogues to cross-link and label P2X receptors (2009) (10)
- Effects of P2Y 1 and P2Y 12 receptor antagonists on ADP-induced shape change of equine platelets: comparison with human platelets (2002) (10)
- Calcium Signalling through Ligand-Gated Ion Channels such as P2X1 Receptors in the Platelet and other Non-Excitable Cells. (2016) (10)
- Alternative Methods and Their Application in Neurotoxicity Testing (1991) (10)
- Characteristics of the allosteric mode of action for the human P2X7 receptor antagonists AZ11645373, brilliant blue G, KN-62, calmidazolium and ZINC58368839. (2019) (10)
- Involvement of T‐type calcium channels in excitatory junction potentials in rat resistance mesenteric arteries (2002) (9)
- Development of a P2X1‐purinoceptor mediated contractile response in the aged mouse prostate gland through slowing down of ATP breakdown (2015) (9)
- Use of Chimeras, Point Mutants, and Molecular Modeling to Map the Antagonist-binding Site of 4,4′,4″,4‴-(Carbonylbis-(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakisbenzene-1,3-disulfonic Acid (NF449) at P2X1 Receptors for ATP* (2014) (8)
- Contribution of the intracellular C terminal domain to regulation of human P2X1 receptors for ATP by phorbol ester and Gq coupled mGlu1α receptors (2011) (8)
- Experimental thrombus formation in mesenteric microvessels: evaluation of a method. (1973) (7)
- P2X1 receptor mobility and trafficking; regulation by receptor insertion and activation. (2010) (7)
- Inhibition of vasoconstriction and Ca2+ currents mediated by neuropeptide Y Y2 receptors. (1999) (7)
- A method for loading equine platelets with the fluorescent calcium indicator Fura-2: ADP induces a rise in the cytosolic free calcium ion concentration. (1993) (6)
- P2X1 ion channel deficiency causes massive bleeding in inflamed intestine and increases thrombosis (2020) (6)
- Inhibition of transmitter release from sympathetic nerve endings by omega-conotoxin. (1989) (6)
- The morphological differentiation of cultured astrocytes induced by ionomycin: lack of dependence on protein kinase C activation (1987) (6)
- Development of a P2X1-eYFP receptor knock-in mouse to track receptors in real time (2019) (5)
- Lysosomal storage diseases in dogs and cats (1989) (5)
- Chronic granulocytic leukaemia in a dog with associated bacterial endocarditis, thrombocytopenia and preretinal and retinal haemorrhages (1987) (4)
- Cooperation between NMDA-Type Glutamate and P2 Receptors for Neuroprotection during Stroke: Combining Astrocyte and Neuronal Protection (2018) (4)
- Contribution of P2X1 receptor intracellular basic residues to channel properties. (2006) (4)
- Organization of ATP-gated P2X1 receptor intracellular termini in apo and desensitized states (2019) (4)
- Contribution of P2Y1 receptors to ADP signalling in mouse spinal cord cultures (2008) (3)
- Comparison of the complement fixation test and the indirect hemolysis test for cattle vaccinated and infected with Brucella abortus (1982) (3)
- The inhibition of adenylate cyclase in equine platelets by collagen and by platelet-activating factor. (1996) (3)
- Identification of a distinct desensitisation gate in the ATP-gated P2X2 receptor (2019) (2)
- Permeability and single‐channel properties of mesenteric, basilar, and septal (coronary) artery smooth‐muscle P2X receptors (2001) (2)
- A key role of the fast ATP-gated P2X1cation channel in the thrombosis of small arteriesin vivo (2003) (1)
- Molecular Mechanism of Resistance of Equine (Equus caballus) Platelets to α2-Adrenergic Regulation (1997) (1)
- Inhibition of platelet thrombus formation by dextran. (1973) (1)
- Letter: Mechanism of the antithrombotic action of dextran. (1974) (1)
- P2X receptors (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database (2020) (1)
- Chemotaxis through Rho Kinase Activation Ion Channels Promote Neutrophil 1 P 2 X Data (2009) (1)
- Lack of P2X1 ion channels increases endotoxemia associated coagulation and organ damage through neutrophil hyperresponsiveness. (2011) (0)
- The role of cysteine residues and disulphide bonds in P2X 1 receptor function (2001) (0)
- receptor signaling megakaryocyte represents a fully functional model of platelet P2 megakaryocyte cation influx currents by ADP: evidence that the primary Interplay between P2Y1, P2Y12, and P2X1 receptors in the activation of (2013) (0)
- Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120 (2017) (0)
- P2X Receptors for ATP: Classification, Distribution, and Function (2000) (0)
- Cellular Signalling C133‐C151, PC47‐PC70 (2004) (0)
- P2X receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
- UK Purine Club 2010 Abstracts (2010) (0)
- Functional Regulation of P2X 6 Receptors by N -Linked Glycosylation: Identification of a Novel (cid:1)(cid:2) -Methylene ATP-Sensitive Phenotype (2004) (0)
- Species-specific toxic effects of α-chlorohydrin and 6-chloro-6-deoxyglucose on astrocytes (1990) (0)
- Specific antibody responses to immunization with diphtheria (D) and tetanus (T) in steroid and non-steroid dependent asthmatics (1982) (0)
- Smooth muscle does not have a common P receptor phenotype : 2 x expression , ontogeny and function of P receptors in mouse ileum , 2 x 1 bladder and reproductive systems (2001) (0)
- Species-specific toxic effects of alpha-chlorohydrin and 6-chloro-6-deoxyglucose on astrocytes. (1990) (0)
- Cysteine substitution mutagenesis at human P2X2 and P2X4 receptors indicates a common mode of ATP action at P2X receptors (2008) (0)
- Synaptic Transmission at the Calyx of Held but Not P2X Receptors, During High-Frequency Endogenous Activation of Adenosine A1 Receptors, (2015) (0)
- Acute neurological crisis: A toxicological commentary (1989) (0)
- An effective treatment of hypercholesterolaemia. Use of a combination of a bile acid sequestrant and clofibrate. (1972) (0)
- Oestradiol rapidly regulates calcium signals in ciliary neurons from the chick embryo (2004) (0)
- Endotoxemia in Mice Lipopolysaccharide-Induced Lethal Neutrophil Extravasation during Receptor Is Required for 1 The P2X (2014) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Richard J Evans?
Richard J Evans is affiliated with the following schools:
