Richard Jackson
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British biochemist
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Richard Jackson biology Degrees
Biology
#2577
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#4067
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Molecular Biology
#687
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#704
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Biochemistry
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#975
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Biology
Richard Jackson 's Degrees
- Bachelors Biochemistry University of Oxford
Why Is Richard Jackson Influential?
(Suggest an Edit or Addition)According to Wikipedia, Richard Jackson is a biochemist and cell biologist. He is Emeritus Professor of RNA Biochemistry in the Department of Biochemistry at the University of Cambridge. In 2006, Jackson was elected a Fellow of the Royal Society. Jackson's main contributions to cell biology concern the translation of a cell's genetic instruction by ribosomes into proteins, utilizing messenger RNA.
Richard Jackson 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- An efficient mRNA-dependent translation system from reticulocyte lysates. (1976) (3055)
- The mechanism of eukaryotic translation initiation and principles of its regulation (2010) (2390)
- A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs. (1998) (754)
- Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis (1977) (582)
- Do the poly(A) tail and 3′ untranslated region control mRNA translation? (1990) (556)
- Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA. (1983) (457)
- Cytoplasmic regulation of mRNA function: The importance of the 3′ untranslated region (1993) (383)
- Unique features of internal initiation of hepatitis C virus RNA translation. (1995) (382)
- The novel mechanism of initiation of picornavirus RNA translation. (1990) (357)
- Internal initiation of translation in eukaryotes: the picornavirus paradigm and beyond. (1995) (357)
- How Do MicroRNAs Regulate Gene Expression? (2007) (328)
- Life and death in the cytoplasm: messages from the 3' end. (1997) (323)
- unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA. (1999) (261)
- The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr. (2003) (245)
- Direct evidence that polypyrimidine tract binding protein (PTB) is essential for internal initiation of translation of encephalomyocarditis virus RNA. (1995) (240)
- In vitro translation of poliovirus RNA: utilization of internal initiation sites in reticulocyte lysate (1984) (239)
- Initiation of protein synthesis: evidence for messenger RNA-independent binding of methionyl-transfer RNA to the 40 S ribosomal subunit. (1973) (224)
- Termination and post-termination events in eukaryotic translation. (2012) (221)
- Alternative mechanisms of initiating translation of mammalian mRNAs. (2005) (213)
- The characteristics of inhibition of protein synthesis by double-stranded ribonucleic acid in reticulocyte lysates. (1975) (212)
- Initiation of encephalomyocarditis virus RNA translation: the authentic initiation site is not selected by a scanning mechanism. (1990) (209)
- Role of Methionine in the Initiation of Haemoglobin Synthesis (1970) (196)
- What determines whether mammalian ribosomes resume scanning after translation of a short upstream open reading frame? (2004) (167)
- Polypyrimidine-tract binding protein (PTB) is necessary, but not sufficient, for efficient internal initiation of translation of human rhinovirus-2 RNA. (1999) (160)
- Internal initiation of translation of hepatitis C virus RNA: the ribosome entry site is at the authentic initiation codon. (1996) (156)
- The current status of vertebrate cellular mRNA IRESs. (2013) (152)
- Protein Factor Requirements of the Apaf-1 Internal Ribosome Entry Segment: Roles of Polypyrimidine Tract Binding Protein and upstream of N-ras (2001) (149)
- Differential alternative splicing activity of isoforms of polypyrimidine tract binding protein (PTB). (2001) (147)
- Control of protein synthesis in reticulocyte lysates by haemin. (1973) (145)
- MicroRNAs repress translation of m7Gppp-capped target mRNAs in vitro by inhibiting initiation and promoting deadenylation. (2007) (142)
- Translation of encephalomyocarditis virus RNA: parameters influencing the selection of the internal initiation site. (1994) (139)
- The involvement of a spliceosome component in internal initiation of human rhinovirus RNA translation. (1993) (138)
- The polypyrimidine tract binding protein (PTB) requirement for internal initiation of translation of cardiovirus RNAs is conditional rather than absolute. (1998) (129)
- Activity of the Hepatitis A Virus IRES Requires Association between the Cap-Binding Translation Initiation Factor (eIF4E) and eIF4G (2001) (123)
- Initiation of translation of human rhinovirus RNA: mapping the internal ribosome entry site. (1992) (120)
- The role of polyamines in cell-free protein synthesis in the wheat-germ system. (1977) (115)
- Double‐stranded DNA induces the phosphorylation of several proteins including the 90 000 mol. wt. heat‐shock protein in animal cell extracts. (1985) (114)
- Pestivirus Internal Ribosome Entry Site (IRES) Structure and Function: Elements in the 5′ Untranslated Region Important for IRES Function (2002) (113)
- Regulation of translation by specific protein/mRNA interactions. (1994) (113)
- The immediate downstream codon strongly influences the efficiency of utilization of eukaryotic translation initiation codons. (1994) (102)
- 4 A Comparative View of Initiation Site Selection Mechanisms (2000) (93)
- The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation. (2007) (89)
- Polypyrimidine tract binding protein stabilizes the encephalomyocarditis virus IRES structure via binding multiple sites in a unique orientation. (2009) (84)
- Cap-dependent and cap-independent translation: operational distinctions and mechanistic interpretations. (1995) (84)
- Translational controls impinging on the 5'-untranslated region and initiation factor proteins. (1997) (84)
- Defining the roles and interactions of PTB. (2012) (80)
- The effect of cyclic AMP and related compounds on the control of protein synthesis in reticulocyte lysates. (1974) (78)
- Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation (2001) (78)
- Plasmid cDNA-directed protein synthesis in a coupled eukaryotic in vitro transcription-translation system. (1992) (72)
- Polypyrimidine tract‐binding protein stimulates the poliovirus IRES by modulating eIF4G binding (2010) (72)
- The mechanism of translation initiation on Aichivirus RNA mediated by a novel type of picornavirus IRES (2011) (71)
- On the fidelity of mRNA translation in the nuclease-treated rabbit reticulocyte lysate system. (1989) (69)
- The preparation and properties of gel-filtered rabbit-reticulocyte lysate protein-synthesis systems. (1983) (62)
- Analysis of phosphorylation of protein synthesis initiation factor eIF-2 by two-dimensional gel electrophoresis. (1978) (61)
- A complex between met-tRNA F and native 40S subunits in reticulocyte lysates and its disappearance during incubation with double-stranded RNA. (1972) (60)
- Characterization of the termination-reinitiation strategy employed in the expression of influenza B virus BM2 protein. (2008) (57)
- The influence of viral coding sequences on pestivirus IRES activity reveals further parallels with translation initiation in prokaryotes. (2002) (54)
- Efficient initiation of mammalian mRNA translation at a CUG codon. (1989) (53)
- Control of protein synthesis in reticulocyte lysates: the effect of nucleotide triphosphates on formation of the translational repressor. (1975) (53)
- The roles of sugar phosphates and thiol-reducing systems in the control of reticulocyte protein synthesis. (1983) (52)
- Selection of the 5'-proximal translation initiation site is influenced by mRNA and eIF-2 concentrations. (1990) (49)
- The ATP requirement for initiation of eukaryotic translation varies according to the mRNA species. (1991) (48)
- Poliovirus Internal Ribosome Entry Segment Structure Alterations That Specifically Affect Function in Neuronal Cells: Molecular Genetic Analysis (2002) (47)
- Picornaviruses break the rules (1988) (46)
- The awesome power of ribosome profiling (2015) (44)
- Internal initiation of translation of picornavirus RNAs (1994) (44)
- Expression of the VP2 Protein of Murine Norovirus by a Translation Termination-Reinitiation Strategy (2009) (42)
- Internal initiation of translation from the human rhinovirus-2 internal ribosome entry site requires the binding of Unr to two distinct sites on the 5' untranslated region. (2007) (42)
- Potassium salts influence the fidelity of mRNA translation initiation in rabbit reticulocyte lysates: unique features of encephalomyocarditis virus RNA translation. (1991) (42)
- The use of affinity chromatography on 2'5' ADP-sepharose reveals a requirement for NADPH, thioredoxin and thioredoxin reductase for the maintenance of high protein synthesis activity in rabbit reticulocyte lysates. (1983) (41)
- Prokaryotic and eukaryotic translation factors (1996) (40)
- The properties of chimeric picornavirus IRESes show that discrimination between internal translation initiation sites is influenced by the identity of the IRES and not just the context of the AUG codon. (1999) (39)
- Defective point mutants of the encephalomyocarditis virus internal ribosome entry site can be complemented in trans. (1995) (37)
- The role of complexes between the 40-S ribosomal subunit and Met-tRNA-Met-f in the initiation of protein synthesis in the wheat-germ system. (1977) (36)
- Initiation without an end (1991) (36)
- The influence of viral coding sequences on the efficiency of internal initiation of translation of cardiovirus RNAs. (1993) (35)
- Chapter 9 Viral Strategies to Subvert the Mammalian Translation Machinery (2009) (34)
- The rabbit reticulocyte lysate as a system for studying mRNA. (1974) (33)
- Activation of picornaviral IRESs by PTB shows differential dependence on each PTB RNA-binding domain. (2011) (32)
- 31 Translation Initiation on Picornavirus RNA (2000) (32)
- Expression of Human nPTB Is Limited by Extreme Suboptimal Codon Content (2008) (30)
- Activation of a microRNA response in trans reveals a new role for poly(A) in translational repression (2011) (29)
- The Rubella Virus Nonstructural Protease Requires Divalent Cations for Activity and Functions in trans (1998) (29)
- All five cold-shock domains of unr (upstream of N-ras) are required for stimulation of human rhinovirus RNA translation. (2004) (29)
- Construction of regulatable picornavirus IRESes as a test of current models of the mechanism of internal translation initiation. (2001) (25)
- The Cytoplasmic Control of Protein Synthesis (1982) (24)
- 8 Coupled Termination-Reinitiation Events in mRNA Translation (2007) (24)
- Multiple proteins and subgenomic mRNAs may be derived from a single open reading frame on tobacco mosaic virus RNA. (1983) (23)
- Translational Regulation: Y the message is masked? (1994) (22)
- Development of a tRNA-dependent in vitro translation system. (2001) (21)
- Preparation and properties of an improved cell-free protein synthesis system from mammalian liver. (1985) (21)
- Further Characterisation of the Translational Termination-Reinitiation Signal of the Influenza B Virus Segment 7 RNA (2011) (21)
- Proteins Involved in the Function of Picornavirus Internal Ribosomal Entry Sites (2002) (20)
- Internal initiation of mRNA translation in eukaryotes. (1994) (20)
- Rhinovirus 2A proteinase mediated stimulation of rhinovirus RNA translation is additive to the stimulation effected by cellular RNA binding proteins. (1999) (17)
- Mechanism of Initiation Site Selection Promoted by the Human Rhinovirus 2 Internal Ribosome Entry Site (2010) (17)
- Substitution mutations at the putative catalytic triad of the poliovirus 3C protease have differential effects on cleavage at different sites. (1993) (17)
- Analysis of in vitro and in vivo products of the TMV 30kDa open reading frame using antisera raised against a synthetic peptide (1983) (16)
- The organization of RNA contacts by PTB for regulation of FAS splicing (2014) (14)
- Mapping of the Internal Ribosome Entry Site at the 5′ End of the Hepatitis C Virus Genome (1994) (14)
- The heat-shock response in Drosophila KC 161 cells. mRNA competition is the main explanation for reduction of normal protein synthesis. (1986) (14)
- A novel approach to the isolation of rabbit reticulocyte haem-controlled eIF-2α protein kinase (1985) (13)
- Mechanisms Governing the Selection of Translation Initiation Sites on Foot-and-Mouth Disease Virus RNA (2011) (12)
- RNA translation. Picornaviruses break the rules. (1988) (12)
- The translation of capped mRNAs has an absolute requirement for the central domain of eIF4G but not for the cap-binding initiation factor eIF4E. (2001) (11)
- The use of hexose phosphates to support protein synthesis and generate [γ‐32P]ATP in reticulocyte lysates (1978) (11)
- Modulation of expression of the hepatitis B virus surface antigen gene by the viral X-gene product (1990) (11)
- A rabbit reticulocyte factor which stimulates protein synthesis in several mammalian cell-free systems. (1985) (11)
- Differential effects of nucleotide analogs on scanning-dependent initiation and elongation of mammalian mRNA translation in vitro. (2010) (9)
- mRNA translation. Initiation without an end. (1991) (7)
- The missing link in the eukaryotic ribosome cycle. (2007) (6)
- Translation: Cinderella factors have a ball (1998) (5)
- 3 A Comparative View of Initiation Site Selection Mechanisms (1996) (5)
- 16 The Shapely mRNA: Knotting Ventured, Knotting Gained (2006) (5)
- The turnover of methionine in the Met‐tRNA pool and the control of protein synthesis in reticulocyte lysates (1982) (5)
- The effect of cobalt on the synthesis of globin and haem in reticulocytes (1970) (5)
- Initiation of Eukaryotic Protein Synthesis: Native 40S Subunits Bind Initiator Transfer Ribonucleic Acid before Associating with Messenger Ribonucleic Acid (1973) (3)
- The Mechanism and Cytoplasmic Control of Mammalian Protein Synthesis (1979) (3)
- A novel approach to the isolation of rabbit reticulocyte haem-controlled eIF-2 alpha protein kinase. (1985) (2)
- Mechanisms on control of polypeptide-chain initiation in reticulocytes. (1980) (1)
- Control of polypeptide chain initiation by sugar phosphates. (1985) (1)
- FREE with your next issue of TiBS: A Trends Guide to Proteomics (2001) (0)
- 587 th Meeting Held at the University of Dundee on 26 , 2 7 and 2 8 March 1980 Physiological Control Mechanisms of Protein Synthesis in Animal Cells (2009) (0)
- Translation ofencephalomyocarditis virus RNA: parameters influencing theselection oftheinternal initiation site (1994) (0)
- Processing of the Encephalomyocarditis Virus Capsid Precursor Protein Studied in Rabbit Reticulocyte Lysates (0)
- Frontmatter (1990) (0)
- TRANSLATIONAL CONTROL OF PROTEIN SYNTHESIS IN RETICULOCYTES (1981) (0)
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