Richard K. Assoian
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Richard K. Assoianbiology Degrees
Biology
#11068
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#14443
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Cell Biology
#541
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#553
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Molecular Biology
#1664
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#1692
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Neuroscience
#1768
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#1824
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Biology
Richard K. Assoian's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
Why Is Richard K. Assoian Influential?
(Suggest an Edit or Addition)Richard K. Assoian's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. (1986) (2840)
- Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells (1985) (1667)
- Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization. (1983) (1395)
- Transforming growth factor-beta: biological function and chemical structure. (1986) (1115)
- Expression and secretion of type beta transforming growth factor by activated human macrophages. (1987) (1025)
- Integrins and cell proliferation: regulation of cyclin-dependent kinases via cytoplasmic signaling pathways. (2001) (557)
- Type beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells (1986) (508)
- Integrating the MAP kinase signal into the G1 phase cell cycle machinery. (2000) (504)
- Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein (1996) (489)
- Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation. (1995) (416)
- A link between cyclin A expression and adhesion-dependent cell cycle progression. (1993) (414)
- Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes. (1985) (407)
- Anchorage-dependent Cell Cycle Progression (1997) (400)
- Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening (2009) (385)
- Cellular transformation by coordinated action of three peptide growth factors from human platelets (1984) (380)
- Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression. (2001) (337)
- Induction of transforming growth factor-α in activated human alveolar macrophages (1988) (321)
- Transcriptional regulation of the cyclin D1 gene at a glance (2008) (320)
- The adhesion receptor CD44 promotes atherosclerosis by mediating inflammatory cell recruitment and vascular cell activation. (2001) (287)
- Growth control by intracellular tension and extracellular stiffness. (2008) (249)
- Integrin-Mediated Adhesion Regulates ERK Nuclear Translocation and Phosphorylation of Elk-1 (2001) (247)
- Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1. (1996) (244)
- N-Cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells (2016) (237)
- Transforming growth factor-β controls receptor levels for epidermal growth factor in NRK fibroblasts (1984) (224)
- Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression. (1997) (215)
- α5β1 Integrin Controls Cyclin D1 Expression by Sustaining Mitogen-activated Protein Kinase Activity in Growth Factor-treated Cells (1999) (212)
- The mechanical regulation of integrin–cadherin crosstalk organizes cells, signaling and forces (2016) (209)
- Regulation of the cytoskeleton: an oncogenic function for cdk inhibitors? (2004) (198)
- A FAK-Cas-Rac-Lamellipodin Signaling Module Transduces Extracellular Matrix Stiffness into Mechanosensitive Cell Cycling (2014) (180)
- Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening. (2012) (162)
- Fibroblast migration is mediated by CD44-dependent TGFβ activation (2008) (151)
- Regulation of P21cip1 Expression by Growth Factors and the Extracellular Matrix Reveals a Role for Transient ERK Activity in G1 Phase (1999) (146)
- Increased secretion of type beta transforming growth factor accompanies viral transformation of cells. (1985) (140)
- Timing of cyclin D1 expression within G1 phase is controlled by Rho (2009) (137)
- Timing of cyclin D1 expression within G1 phase is controlled by Rho (2001) (136)
- From tissue mechanics to transcription factors. (2013) (135)
- G1/S control of anchorage-independent growth in the fibroblast cell cycle (1991) (131)
- Integrin-dependent signal transduction regulating cyclin D1 expression and G1 phase cell cycle progression (2005) (119)
- Biphasic effects of type beta transforming growth factor on epidermal growth factor receptors in NRK fibroblasts. Functional consequences for epidermal growth factor-stimulated mitosis. (1985) (117)
- Transforming growth factor-beta 1 inhibits scavenger receptor activity in THP-1 human macrophages. (1991) (115)
- A simple indentation device for measuring micrometer-scale tissue stiffness (2010) (104)
- Regulation of growth factor signaling and cell cycle progression by cell adhesion and adhesion-dependent changes in cellular tension. (2005) (100)
- The extracellular matrix as a cell cycle control element in atherosclerosis and restenosis. (1996) (100)
- Rheostatic signaling by CD44 and hyaluronan. (2009) (94)
- Microsomal Prostaglandin E2 Synthase-1 Modulates the Response to Vascular Injury (2011) (88)
- Effects of Rho Kinase and Actin Stress Fibers on Sustained Extracellular Signal-Regulated Kinase Activity and Activation of G1 Phase Cyclin-Dependent Kinases (2003) (87)
- Phorbol Ester-induced G1 Phase Arrest Selectively Mediated by Protein Kinase Cδ-dependent Induction of p21* (2005) (85)
- Induction of transforming growth factor-alpha in activated human alveolar macrophages. (1988) (85)
- Differential Activation of ERK and Rac Mediates the Proliferative and Anti-proliferative Effects of Hyaluronan and CD44* (2008) (82)
- ABCG2 expression and side population abundance regulated by a transforming growth factor beta-directed epithelial-mesenchymal transition. (2008) (81)
- Cell adhesion to extracellular matrix regulates the life cycle of integrins. (1995) (80)
- Three-dimensional biomimetic vascular model reveals a RhoA, Rac1, and N-cadherin balance in mural cell–endothelial cell-regulated barrier function (2017) (79)
- The Absence of Caveolin-1 Increases Proliferation and Anchorage- Independent Growth by a Rac-Dependent, Erk-Independent Mechanism (2009) (77)
- ERK activity and G1 phase progression: identifying dispensable versus essential activities and primary versus secondary targets. (2007) (77)
- Hyaluronan and CD44 antagonize mitogen-dependent cyclin D1 expression in mesenchymal cells (2007) (74)
- Cell attachment controls fibronectin and alpha 5 beta 1 integrin levels in fibroblasts. Implications for anchorage-dependent and -independent growth. (1992) (72)
- Studying the effects of matrix stiffness on cellular function using acrylamide-based hydrogels. (2010) (69)
- The extracellular matrix and mitogenic growth factors control G1 phase cyclins and cyclin-dependent kinase inhibitors. (1997) (68)
- Type VIII collagen mediates vessel wall remodeling after arterial injury and fibrous cap formation in atherosclerosis. (2013) (66)
- Gaussian Curvature Directs Stress Fiber Orientation and Cell Migration. (2018) (63)
- Transforming growth factor-beta increases transcription of the genes encoding the epidermal growth factor receptor and fibronectin in normal rat kidney fibroblasts. (1988) (62)
- Semisynthesis and biological activity of porcine [LeuB24]insulin and [LeuB25]insulin. (1980) (62)
- A Skp2 autoinduction loop and restriction point control (2007) (62)
- Prostacylin receptor activation inhibits proliferation of aortic smooth muscle cells by regulating cAMP response element-binding protein- and pocket protein-dependent cyclin a gene expression. (2003) (59)
- Curvature and Rho activation differentially control the alignment of cells and stress fibers (2017) (57)
- N-Cadherin Induction by ECM Stiffness and FAK Overrides the Spreading Requirement for Proliferation of Vascular Smooth Muscle Cells (2015) (57)
- Cell adhesion, cellular tension, and cell cycle control. (2007) (57)
- Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesion (2008) (55)
- Matrix metalloproteinase-12 is an essential mediator of acute and chronic arterial stiffening (2015) (53)
- Heregulin beta1 promotes breast cancer cell proliferation through Rac/ERK-dependent induction of cyclin D1 and p21Cip1. (2008) (52)
- Nuclear translocation of LIM kinase mediates Rho-Rho kinase regulation of cyclin D1 expression. (2003) (51)
- Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility (2017) (51)
- Antimitogenic effects of HDL and APOE mediated by Cox-2-dependent IP activation. (2004) (50)
- Effects of Rho Kinase and Actin Stress Fibers on Sustained Extracellular Signal-Regulated Kinase Activity and Activation of G1 Phase Cyclin-Dependent Kinases (2006) (49)
- Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments (2015) (48)
- Peptide intermediates in the cellular metabolism of insulin. (1982) (48)
- A reciprocal relationship between Rb and Skp2: implications for restriction point control, signal transduction to the cell cycle, and cancer (2008) (45)
- Vascular smooth muscle cell‐specific progerin expression in a mouse model of Hutchinson–Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite (2019) (43)
- Stiffness-dependent motility and proliferation uncoupled by deletion of CD44 (2017) (41)
- Mining the Stiffness-Sensitive Transcriptome in Human Vascular Smooth Muscle Cells Identifies Long Noncoding RNA Stiffness Regulators (2018) (41)
- Type beta 1 transforming growth factor gene expression. A corrected mRNA structure reveals a downstream phorbol ester responsive element in human cells. (1990) (40)
- Distinct Effects of Mitogens and the Actin Cytoskeleton on CREB and Pocket Protein Phosphorylation Control the Extent and Timing of Cyclin A Promoter Activity (2001) (39)
- Control of the G1 phase cyclin-dependent kinases by mitogenic growth factors and the extracellular matrix. (1997) (36)
- Joint Requirement for Rac and ERK Activities Underlies the Mid-G1 Phase Induction of Cyclin D1 and S Phase Entry in Both Epithelial and Mesenchymal Cells* (2008) (32)
- Antimitogenesis Linked to Regulation of Skp2 Gene Expression* (2004) (27)
- Cardiovascular protection in females linked to estrogen-dependent inhibition of arterial stiffening and macrophage MMP12. (2019) (27)
- The extracellular matrix as a cell cycle control element in atherosclerosis and restenosis. (1997) (25)
- NFκB-Independent Signaling to the Cyclin D1 Gene by Rac (2007) (24)
- Stopping and going with p27kip1. (2004) (24)
- BIOSYNTHESIS OF ISLET CELL HORMONES (1980) (24)
- Common sense signalling (2002) (24)
- Apolipoprotein E-mediated cell cycle arrest linked to p27 and the Cox2-dependent repression of miR221/222. (2013) (23)
- Purification of type-beta transforming growth factor from human platelets. (1987) (23)
- Cellular sensing of micron-scale curvature: a frontier in understanding the microenvironment (2019) (21)
- Iodotyrosylation of peptides using tertiary-Butyloxycarbonyl-L-[125I]iodotyrosine N-hydroxysuccinimide ester. (1980) (20)
- miR-221/222 Compensates for Skp2-Mediated p27 Degradation and Is a Primary Target of Cell Cycle Regulation by Prostacyclin and cAMP (2013) (20)
- [LeuB24]insulin and [AlaB24]insulin: altered structures and cellular processing of B24-substituted insulin analogs. (1982) (19)
- NFkappaB-independent signaling to the cyclin D1 gene by Rac. (2007) (19)
- [(125I]IodotyrosylB1]insulin. Semisynthesis, receptor binding, and cell-mediated degradation of a B chain-labeled insulin. (1981) (18)
- Transforming Growth Factor-β Overrides the Adhesion Requirement for Surface Expression of α5β1 Integrin in Normal Rat Kidney Fibroblasts (1999) (17)
- Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U 937 monocytes ( cell migration / phorbol ester / proteolysis ) (16)
- Nuclear translocation of LIM kinase mediates Rho-Rho kinase regulation of cyclin D1 expression. (2003) (16)
- Perspectives Series: Cell Adhesion in Vascular Biology (1996) (15)
- Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy. (2016) (14)
- Heregulin β 1 promotes breast cancer cell proliferation through Rac / ERK-dependent induction of cyclin D 1 and p 21 Cip 1 (2008) (14)
- Induction of Anchorage-independent Growth by Transforming Growth Factor-β Linked to Anchorage-independent Expression of Cyclin D1* (2000) (13)
- Heterogeneity of glucagon receptors of rat hepatocytes: a synthetic peptide probe for the high affinity site. (1984) (13)
- Post-transcriptional Destabilization of p21cip1 by Protein Kinase C in Fibroblasts* (2006) (13)
- Apolipoprotein E3 Inhibits Rho to Regulate the Mechanosensitive Expression of Cox2 (2015) (13)
- Arterial stiffness and cardiac dysfunction in Hutchinson–Gilford Progeria Syndrome corrected by inhibition of lysyl oxidase (2021) (12)
- Myeloid Cell 5-Lipoxygenase Activating Protein Modulates the Response to Vascular Injury (2013) (12)
- MMP12 preferentially attenuates axial stiffening of aging arteries. (2019) (11)
- Mechanosensitive smooth muscle cell phenotypic plasticity emerging from a null state and the balance between Rac and Rho (2021) (10)
- Decreased vascular smooth muscle contractility in Hutchinson–Gilford Progeria Syndrome linked to defective smooth muscle myosin heavy chain expression (2021) (10)
- Edges impose planar alignment in nematic monolayers by directing cell elongation and enhancing migration. (2018) (9)
- Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure. (2021) (8)
- Increased Secretion ofTypeC3Transforming GrowthFactor Accompanies Viral Transformation ofCells (1985) (7)
- Cell-type- and cell-cycle-specific anti-mitogenesis by cicaprost. (2010) (5)
- Fibroblast activation protein regulates lesion burden and the fibro-inflammatory response in Apoe-deficient mice in a sexually dimorphic manner. (2020) (5)
- Attachment Control of Fibroblast Proliferation (1993) (4)
- Structure and function of transforming growth factor-beta. (1986) (4)
- Antimitogenic effects of prostacyclin on the G1 phase cyclin-dependent kinases. (2005) (3)
- Patterned Cell Alignment in Response to Macroscale Curvature (2017) (3)
- Kinases Phase Cyclin-Dependent 1 Activation of G Signal-Regulated Kinase Activity and Fibers on Sustained Extracellular Effects of Rho Kinase and Actin Stress (2003) (3)
- Apolipoprotein E 3 Inhibits Rho to Regulate the Mechanosensitive Expression of Cox 2 (2015) (2)
- Cell contractility and focal adhesion kinase control circumferential arterial stiffness (2022) (1)
- Abstract 15589: Matrix Metalloproteinase-12 Controls Arterial Stiffness in Vascular Remodeling (2012) (1)
- RAGE antagonist peptide mitigates AGE-mediated endothelial hyperpermeability and accumulation of glycoxidation products in human ascending aortas and in a murine model of aortic aneurysm (2021) (1)
- MMP12 Deletion Preferentially Attenuates Axial Stiffening of Aging Arteries (2019) (1)
- Role of Cyclin D1 and cdk Inhibitors in Breast Cancer Pathogenesis (1999) (0)
- Role of the Extracellular Matrix and Cytoskeleton in the Regulation of Cyclins, Cyclindependent Kinase Inhibitors, and Anchorage-Dependent Growth (1997) (0)
- Progerin mislocalizes myocardin-related transcription factor in Hutchinson–Guilford Progeria syndrome (2022) (0)
- Premature induction of Lysyl Oxidase drives early arterial stiffening in Hutchinson-Gilford Progeria Syndrome (2019) (0)
- 2017 Reviewer Acknowledgment (2018) (0)
- The Role of Type VIII Collagen in Arterial Vessel Stiffening (2018) (0)
- Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness : Therapeutic effect of dietary nitrite Running title : VSMCs and arterial stiffness in progeria (2019) (0)
- Methods for Analysis of Adhesion-Dependent Cell Cycle Progression (2019) (0)
- Science Signaling Podcast: 17 June 2014 (2014) (0)
- Stiffness-dependent motility and proliferation uncoupled by deletion of CD44 (2017) (0)
- Purified transforming growth factor-beta plaques from human placentas and coming. (1984) (0)
- Abstract 13682: 5-Lipoxygenase Activating Protein Attenuates the Response to Vascular Injury (2011) (0)
- Efemp1 modulates elastic fiber formation and mechanics of the extrahepatic bile duct (2021) (0)
- Abstract 17597: Deletion of Fibroblast Activation Protein (FAP) Attenuates Atherosclerotic Lesion Development via Changes in the Accumulation of Fibrillar Collagen and in Inflammatory Cell Recruitment (2013) (0)
- Shape-dependent Cell Proliferation (0)
- Extracellular matrix and integrin-signaling in the regulation of cell growth (1999) (0)
- Transforming growthfactor type,8: Rapidinduction offibrosis and angiogenesis invivoandstimulation ofcollagen formation invitro (1986) (0)
- Cell Linea e Specificity of Expression of the Murine Transforming Growth Factor / 3 and Transforming Growth Factor j Genes (2005) (0)
- Summary Rac-dependent cyclin D 1 gene expression regulated by cadherin-and integrin-mediated adhesion (0)
- Abstract 17707: The Degree of Inflammation Dictates the Role of Smooth Muscle Cell-Specific CD44 and its Effect on Neointimal Formation in Atherosclerosis versus Vascular Injury (2013) (0)
- Rac rather than Rho drives the early transcriptional response to extracellular matrix stiffness and mediates repression of ATF3 (2022) (0)
- Semisynthesis andbiological activity ofporcine (LeuB24)insulin and (LeuB25)insulin (solid-phase peptide synthesis/desoctapeptide insulin/insulin analog/insulin antagonist/rat adipocytes) (1980) (0)
- Edges Impose Planar Alignment in Nematic Monolayers by Directing Cell Elongation and Migration (2018) (0)
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