Richard Lathe
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Richard Lathebiology Degrees
Biology
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Molecular Biology
#359
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Biology
Richard Lathe's Degrees
- Bachelors Biochemistry University of Oxford
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(Suggest an Edit or Addition)Richard Lathe's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Phd by thesis (1988) (12974)
- Synthetic oligonucleotide probes deduced from amino acid sequence data. Theoretical and practical considerations. (1985) (580)
- Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background (1997) (477)
- Expression of rabies virus glycoprotein from a recombinant vaccinia virus (1984) (426)
- Microbes and Alzheimer's Disease. (2016) (367)
- Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene. (1984) (349)
- Breast cancer-associated pS2 protein: synthesis and secretion by normal stomach mucosa. (1988) (348)
- An endocrine pathway in the prostate, ERβ, AR, 5α-androstane-3β,17β-diol, and CYP7B1, regulates prostate growth (2002) (317)
- Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease. (1998) (313)
- The antimicrobial protection hypothesis of Alzheimer's disease (2018) (257)
- Oral vaccination of the fox against rabies using a live recombinant vaccinia virus (1986) (247)
- Genetic basis of Creutzfeldt-Jakob disease in the United Kingdom: a systematic analysis of predisposing mutations and allelic variation in the PRNP gene (1996) (240)
- Hormones and the hippocampus. (2001) (228)
- New versatile cloning and sequencing vectors based on bacteriophage M13. (1983) (228)
- Human epithelial tumor antigen cDNA sequences (1990) (226)
- hSP, the domain‐duplicated homolog of pS2 protein, is co‐expressed with pS2 in stomach but not in breast carcinoma. (1990) (217)
- Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7α-hydroxy dehydroepiandrosterone and 7α-hydroxy pregnenolone (1997) (204)
- Induction of pS2 and hSP genes as markers of mucosal ulceration of the digestive tract. (1991) (178)
- Immunization against human papillomavirus type 16 tumor cells with recombinant vaccinia viruses expressing E6 and E7. (1991) (168)
- Variegated transgene expression in mouse mammary gland is determined by the transgene integration locus. (1996) (166)
- Expression of Human Anti-Hemophilic Factor IX in the Milk of Transgenic Sheep (1989) (164)
- Mice, gene targeting and behaviour: more than just genetic background (1996) (157)
- A Novel Cytochrome P450 Expressed Primarily in Brain (*) (1995) (156)
- Identification and Characterization of a Mouse Oxysterol 7α-Hydroxylase cDNA* (1997) (151)
- An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth. (2002) (143)
- Porphyrinuria in childhood autistic disorder: implications for environmental toxicity. (2006) (143)
- Linker tailing: unphosphorylated linker oligonucleotides for joining DNA termini. (1984) (135)
- Gene Transfer into Sheep (1988) (130)
- The individuality of mice (2004) (115)
- Dehydroepiandrosterone 7-hydroxylase cyp7b: predominant expression in primate hippocampus and reduced expression in alzheimer's disease☆ (2003) (115)
- Variegated gene expression in mice. (1997) (115)
- Plasmid and bacteriophage vectors for excision of intact inserts. (1987) (112)
- Vaccination against tumor cells expressing breast cancer epithelial tumor antigen. (1990) (109)
- Loss of Hippocampal Serine Protease BSP1/Neuropsin Predisposes to Global Seizure Activity (2001) (107)
- High-level production of biologically active human alpha 1-antitrypsin in Escherichia coli. (1984) (103)
- Human epithelial tumor antigen cDNA sequences. Differential splicing may generate multiple protein forms. (1990) (102)
- Atherosclerosis and Alzheimer - diseases with a common cause? Inflammation, oxysterols, vasculature (2014) (99)
- Tumour prevention and rejection with recombinant vaccinia (1987) (98)
- Steroid and sterol 7-hydroxylation: ancient pathways (2002) (97)
- Targeted Inactivation of the Mouse Locus Encoding Coagulation Factor XIII-A: Hemostatic Abnormalities in Mutant Mice and Characterization of the Coagulation Deficit (2002) (96)
- Improved antigenicity of the HIV env protein by cleavage site removal. (1988) (94)
- Serine Proteases in Rodent Hippocampus* (1998) (85)
- Fast tidal cycling and the origin of life (2004) (85)
- Pharmaceuticals from transgenic livestock (1987) (80)
- A ubiquitous mammalian expression vector, pHMG, based on a housekeeping gene promoter. (1989) (76)
- Cell-free synthesis of enterotoxin of E. coli from a cloned gene (1980) (69)
- Steroid signalling in human ovarian surface epithelial cells: the response to interleukin-1alpha determined by microarray analysis. (2004) (69)
- A transcribed gene, containing a variable number of tandem repeats, codes for a human epithelial tumor antigen. cDNA cloning, expression of the transfected gene and over-expression in breast cancer tissue. (1990) (68)
- Neurosteroid Hydroxylase CYP7B (2001) (68)
- The methylation-free status of a housekeeping transgene is lost at high copy number. (1990) (67)
- Early onset of puberty and early ovarian failure in CYP7B1 knockout mice. (2005) (57)
- Comparative proteomic analysis using samples obtained with laser microdissection and saturation dye labelling (2005) (56)
- Expression of the breast cancer associated gene pS2 and the pancreatic spasmolytic polypeptide gene (hSP) in diffuse type of stomach carcinoma. (1991) (56)
- 7 alpha-hydroxylation of 27-hydroxycholesterol: biologic role in the regulation of cholesterol synthesis. (1997) (55)
- Herpes Viruses and Senile Dementia: First Population Evidence for a Causal Link. (2018) (53)
- Breast cancer protein PS2 synthesis in mammary gland of transgenic mice and secretion into milk. (1989) (52)
- Prokaryotic histone-like protein interacting with RNA polymerase. (1980) (51)
- Precocious mammary gland development and milk protein synthesis in transgenic mice ubiquitously expressing human growth hormone. (1991) (49)
- Inherited Creutzfeldt-Jakob disease in a British family associated with a novel 144 base pair insertion of the prion protein gene. (1995) (48)
- Multiple effects of genetic background on variegated transgene expression in mice. (2002) (48)
- Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone. (1997) (46)
- The promiscuous estrogen receptor: Evolution of physiological estrogens and response to phytochemicals and endocrine disruptors (2017) (42)
- Steroid signaling: Ligand-binding promiscuity, molecular symmetry, and the need for gating (2014) (41)
- Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain (2009) (41)
- Comparison of the activity of carp and rat β‐actin gene regulatory sequences in tilapia and rainbow trout embryos (1996) (41)
- Neuropathological phenotype and ‘prion protein’ genotype correlation in sporadic Creutzfeldt-Jakob disease (1994) (36)
- A candidate marsupial PrP gene reveals two domains conserved in mammalian PrP proteins. (1995) (36)
- Dehydroepiandrosterone (DHEA) metabolism in Saccharomyces cerevisiae expressing mammalian steroid hydroxylase CYP7B: Ayr1p and Fox2p display 17β‐hydroxysteroid dehydrogenase activity (2002) (33)
- Isolation and characterization of an expressed hypervariable gene coding for a breast-cancer-associated antigen. (1990) (32)
- Hybridization parameters revisited: solutions containing SDS. (2002) (31)
- Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA. (1997) (29)
- Microbes and Alzheimer’s Disease: New Findings Call for a Paradigm Change (2018) (27)
- Tidal chain reaction and the origin of replicating biopolymers (2005) (26)
- Ontogeny of the neurosteroid enzyme Cyp7b in the mouse (2001) (25)
- Distribution of cellular HSV-1 receptor expression in human brain (2016) (25)
- Autism, brain, and environment (2006) (24)
- Vaccinia recombinants expressing early bovine papilloma virus (BPV1) proteins: retardation of BPV1 tumour development. (1990) (24)
- Early tides: Response to Varga et al. (2006) (24)
- Microbes and Alzheimer's Disease (2017) (23)
- M13 bacteriophage vectors for the expression of foreign proteins in Escherichia coli: the rabies glycoprotein. (1984) (22)
- VIVID REPORTER ACTIVITY IN DENTATE GYRUS OF GENE-TARGETED MICE AND ABOLITION OF A WIDESPREAD PATHWAY OF STEROID AND OXYSTEROL HYDROXYLATION* (2001) (22)
- Differential display detects host nucleic acid motifs altered in scrapie-infected brain. (2009) (21)
- Vaccinia recombinants expressing secreted and transmembrane forms of breast cancer-associated epithelial tumour antigen (ETA). (1991) (21)
- Recombinant Proteins of Therapeutic Interest Expressed by Lymphoid Cell Lines Derived from Transgenic Mice (1989) (19)
- Terpenes, hormones, and life: isoprene rule revisited. (2019) (19)
- Overproduction of a viral protein during infection of a lyc mutant of Escherichia coli with phage lambdamm434. (1977) (19)
- Analysing brain function and dysfunction in transgenic animals (1994) (18)
- A conditionally lethal mutation of Escherichia coli affecting the gene coding for ribosomal protein S2 (rpsB). (1979) (18)
- Novel products from livestock. (1986) (18)
- Erratum: An endocrine pathway in the prostate, ERβ, AR, 5α-androstane-3β,17β-diol, and CYP7B1, regulates prostate growth (Proceedings of the National Academy of Sciences of the United States of America (October 15, 2002) 99, 21 (13589-13594) (DOI: 10.1073/pnas.162477299)) (2006) (18)
- Fine-structure mapping of the firA gene, a locus involved in the phenotypic expression of rifampin resistance in Escherichia (1977) (18)
- Breast cancer sequences identified by mouse mammary tumor virus (MMTV) antiserum are unrelated to MMTV (1990) (17)
- Muramyl peptides activate innate immunity conjointly via YB1 and NOD2 (2016) (17)
- Antiherpetic medication and incident dementia: Observational cohort studies in four countries (2020) (17)
- Prion Protein PRNP: A New Player in Innate Immunity? The Aβ Connection (2017) (16)
- Mechanism Underlying Tissue Cryotherapy to Combat Obesity/Overweight: Triggering Thermogenesis (2018) (15)
- Gene‐trapping to identify and analyze genes expressed in the mouse hippocampus (1998) (15)
- Functional diversity and interactions between the repeat domains of rat intestinal lactase. (1997) (14)
- Influence of Dehydroepiandrosterone on Rabbit Intraocular Pressure (2000) (13)
- Steroid promiscuity: Diversity of enzyme action (2015) (13)
- Porphyrinuria in childhood autistic disorder is not associated with urinary creatinine deficiency (2008) (13)
- RNA polymerase of Escherichia coli. (1978) (12)
- Development of animal recombinant DNA vaccine and its efficacy in foxes. (1988) (12)
- Fragile X and autism (2009) (11)
- Fusion of restriction termini using synthetic adaptor oligonucleotides. (1982) (10)
- The interoceptive hippocampus: Mouse brain endocrine receptor expression highlights a dentate gyrus (DG)–cornu ammonis (CA) challenge–sufficiency axis (2019) (10)
- Mono-allelic Expression of Variegating Transgene Locus in the Mouse (2003) (10)
- Machine-readable DNA sequences (1984) (9)
- Prion protein PrP nucleic acid binding and mobilization implicates retroelements as the replicative component of transmissible spongiform encephalopathy (2020) (8)
- Rabies vaccine: traditional and novel approaches. (1987) (8)
- Innate immunity: Bacterial cell‐wall muramyl peptide targets the conserved transcription factor YB‐1 (2015) (7)
- From conifers to cognition: Microbes, brain and behavior (2020) (7)
- Isolation and characterization of full length cDNA coding for the H23 breast tumor associated antigen (1989) (7)
- New Generation of Rabies Vaccine (1988) (7)
- The firA gene, a locus involved in the expression of rifampicin resistance in Escherichia coli (1977) (7)
- Characterization of polyoma virus early proteins expressed from vaccinia virus recombinants. (1988) (7)
- Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene. 1984. (1992) (6)
- Herpes Infections and Dementia: Rebutting Alternative Fact (2019) (6)
- Reduced dementia incidence after varicella zoster vaccination in Wales 2013–2020 (2022) (6)
- Recombinant polyoma--vaccinia viruses: T antigen expression vectors and anti-tumor immunization agents. (1988) (5)
- The firA gene, a locus involved in the expression of rifampicin resistance in Escherichia coli (1977) (5)
- Environmental Factors and Limbic Vulnerability in Childhood Autism (2008) (5)
- Tidal Cycling and the Origin of the Genetic Code: Implications for Cellular Life (2012) (5)
- The E2 trans-activating protein of bovine papillomavirus type 1 (BPV1) is serine-phosphorylated in vivo. (1989) (5)
- Vaccination against polyoma virus (PYV) tumors using vaccinia‐PYV recombinants: A major tumor‐specific transplantation antigen (TSTA) epitope resides within the C‐terminal segment of middle‐T protein (1990) (4)
- The electronic tree of life (eToL): a net of long probes to characterize the microbiome from RNA-seq data (2021) (4)
- Reduced dementia incidence following varicella zoster vaccination in Wales 2013--2020 (2021) (4)
- Steroid modification in brain; hydroxylation of pregnenolone and DHEA by the novel cytochrome P450, Cyp7b (1997) (4)
- 5 - Cloning and Expression of Viral Antigens in Escherichia coli and Other Microorganisms (1984) (4)
- Sex Ratios Provide Evidence for Monozygotic Twinning in the Ring-Tailed Lemur, Lemur catta (2014) (3)
- Abnormally large, heavy brain with a decreased number of apoptotic cells in CYP7B1 knockout mice (2009) (3)
- Fatty-acylation target sequence in the ligand-binding domain of vertebrate steroid receptors demarcates evolution from estrogen-related receptors (2018) (3)
- Rage et génie dénétique: Développement de nouveaux vaccins (1985) (2)
- Microwave Electromagnetic Radiation and Autism (2009) (2)
- High-level production of biologically active human a 1-antitrypsin in Escherichia coli ( bacterial expression vector / recombinant DNA ) (2)
- Nomenclature and location of bacterial mutations modifying the frequency of lysogenization of E. coli by lambdoid phages (1976) (2)
- Transgenic animals as models for human diseasereport of an EC Study Group (1993) (2)
- Chapter 2.2.3 Brain region-specific genes: the hippocampus (1999) (2)
- DNA engineering: the use of enzymes, chemicals and oligonucleotides to re-structure DNA in vitro (1983) (2)
- Evidence against a geographic gradient of Alzheimer's disease and the hygiene hypothesis (2020) (1)
- Programmed ageing: decline of stem cell renewal, immunosenescence, and Alzheimer's disease. (2023) (1)
- The RNA polymerase of E. coli and the four minute region of the E. coli chromosome (1976) (1)
- Novel DNA sequence representations (reply) (1985) (1)
- Brain region-specific genes : the hippocampus (2004) (1)
- Vaccination against papovavirus-induced tumours using vaccinia recombinants expressing non-structural proteins (1989) (1)
- Anti-stress hormones (2002) (1)
- Revised location of the Escherichia coli gene coding for ribosomal proteins S2 (2004) (1)
- Evolving views on the causes of autistic spectrum disorders (2007) (1)
- Possible origin of the scrapie genome in small endogenous RNAs; studies on eight candidate species in 263K scrapie-infected hamster brain (2019) (1)
- Expression de genes heterologues selon un profil d'expression cible (1994) (0)
- The Question of the Etymology of Dunadd, a fortress of the Dalriadic Scots (2017) (0)
- Vaccine against rabies, as well as process for their preparation (1985) (0)
- A pharmaceutical composition comprising a viral vector (1987) (0)
- Steroides cytoprotecteurs (ii) (2001) (0)
- All That Glisters is Not Gold - Genes, Transgenesis and Behavior (1999) (0)
- Towards a breast cancer vaccine (1989) (0)
- Vaccinia/polyoma recombinant virus: A model for tumour immunity (1987) (0)
- The Early Development of the Vaccinia–Rabies Recombinant Vaccine Raboral® (2021) (0)
- Expression of a tumor-specific antigen, a recombinant virus vector as well as its application to the serving or curative treatment of the corresponding tumor. (1987) (0)
- Explorer Loss of hippocampal serine protease BSP 1 / neuropsin predisposes to global seizure activity (2017) (0)
- Astrobiology: Biochemistry at a distance (2006) (0)
- Use of 7-alpha-substituted steroids for the treatment of neuropsychiatric disorders (1997) (0)
- Expression of heterologous genes in accordance with a målekspressionsprofil (1994) (0)
- Association of antiherpetic medication with incident dementia in Denmark, Wales, Germany and Scotland (2021) (0)
- Production de peptides (1987) (0)
- Microbes and Alzheimer ' s Disease : New Findings 1 Call for a Paradigm Change 2 3 (2018) (0)
- Vaccinia Recombinants Expressing Foreign Antigens: Antiviral and Antitumor Immunity (1989) (0)
- Memory, Alzheimer's disease and the hippocampus: Analysis in transgenic mice (1996) (0)
- Herpes Infections and Dementia: Rebutting Alternative Fact (2019) (0)
- Expression vectors and their use for the preparation of a protein having the activity of human alpha1-antitrypsin (1984) (0)
- Production of peptides (1987) (0)
- Rabies vaccine and methods for preparing. (1985) (0)
- Expression vectors antigenic protein of rabies in eukaryotic cells and their application in the preparation of a vaccine (1983) (0)
- Abrogation of dominant glucose intolerance in SJL mice by a growth hormone transgene. (1991) (0)
- Restricted access data in the neurosciences: Are the restrictions always justified? (2023) (0)
- Evidence that nuclear receptors evolved from terpene synthases (2021) (0)
- Coagulation factor XIII-deficient transgenic animal and its use for the test of wound healing and blödning (1999) (0)
- Author's reply to review of his book on autism (2006) (0)
- The remarkable complexity of the brain microbiome in health and disease (2023) (0)
- Proteine antigenique de la rage glycosylee (1984) (0)
- New expression vectors of the antigenic protein of rabies and their application in the preparation of vaccines (1982) (0)
- Evidence that nuclear receptors are related to terpene synthases (2022) (0)
- Distribution of cellular HSV-1 receptor expression in human brain (2016) (0)
- Microarray studies of human ovarian surface epithelium exposed to an inflammatory stimulus (2004) (0)
- Vectors for expressing a antigenic rabies protein in eucaryotic cells and their application in the preparation of a vaccine (1983) (0)
- Adjuvant effects of multifunctional transcription factor and BCG target YB-1: exogenous YB-1 enhances specific antibody production in vivo and protects mice against lethal E. coli challenge (2022) (0)
- Utilisation de steroides a substitution 7 alpha pour traiter les troubles neuropsychiatriques, immunitaires ou endocriniens (1997) (0)
- Animal transgenique comportant un gène de facteur XIII déficient et utilisation dudit animal pour tester la cicatrisation et l'hemorragie (1999) (0)
- Procede de preparation de steroides modifies par fermentation de levures (2000) (0)
- In memoriam. Jean-Pierre Lecocq, 1947-1992. (1992) (0)
- Proteines associees a l'hippocampe, leur codage par sequences adn et utilisation de ces proteines (1995) (0)
- Pharmaceutical composition for the treatment or prevention of malignant tumors (1991) (0)
- IMPROVED vectors for expression of a protein having the activity of human a1-antitrypsin (1983) (0)
- Molecular Analysis of H23 Epithelial Tumor Antigen - Differentially Spliced Full Length cDNAs and Gene (1991) (0)
- Transgenesis: just half expression (1993) (0)
- family associated with anovel144basepair insertion oftheprion protein gene (2011) (0)
- Genetically Engineered Rabies Subunit Vaccines (1985) (0)
- Vaccination against rabies and process for its preparation (1984) (0)
- LECOCQ,JEAN,PIERRE - A PERSONAL TRIBUTE (1992) (0)
- Expression vectors and their use for the production of a protein with human alpha-antitrypsin activity. (1984) (0)
- Steroid and sterol 7-hydroxylation : ancient pathways 3 (2004) (0)
- The chemosensory brain requires a distributed cellular mechanism to harness information and resolve conflicts – is consciousness the forum? (2016) (0)
- antigenic protein of glycosylated rage (1984) (0)
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Richard Lathe is affiliated with the following schools: