Richard Lee
#135,455
Most Influential Person Now
American cardiac surgeon
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Richard Lee philosophy Degrees
Philosophy
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#15248
Historical Rank
#2099
USA Rank
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World Rank
#9826
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#1248
USA Rank
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Philosophy
Richard Lee 's Degrees
- Doctorate Medicine Harvard University
Why Is Richard Lee Influential?
(Suggest an Edit or Addition)According to Wikipedia, Richard Lee is a cardiac surgeon in St. Louis, Missouri, who helped pioneer a staged Hybrid Maze, a procedure for atrial fibrillation or AFIB. combining surgery and catheter based approaches. He was the vice chair of surgery at Saint Louis University and co-director of the Center for Comprehensive Cardiovascular Care at Saint Louis University Hospital.
Richard Lee 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections (2010) (636)
- Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence. (1999) (610)
- Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans. (2004) (355)
- INHIBITION OF MYCOLIC ACID TRANSPORT ACROSS THE MYCOBACTERIUM TUBERCULOSIS PLASMA MEMBRANE (2011) (349)
- Validation of Molecular Docking Programs for Virtual Screening against Dihydropteroate Synthase (2009) (323)
- Genome-Wide Expression Profiling of the Response to Azole, Polyene, Echinocandin, and Pyrimidine Antifungal Agents in Candida albicans (2005) (318)
- New agents for the treatment of drug-resistant Mycobacterium tuberculosis. (2016) (250)
- First Cultivation and Characterization of Mycobacterium ulcerans from the Environment (2008) (213)
- Combinatorial lead optimization of [1,2]-diamines based on ethambutol as potential antituberculosis preclinical candidates. (2003) (187)
- Heterogeneity of Mycolactones Produced by Clinical Isolates of Mycobacterium ulcerans: Implications for Virulence (2003) (162)
- Biomechanical Evaluation of an Injectable Calcium Phosphate Cement for Vertebroplasty (2002) (158)
- Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase (2012) (157)
- Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis. (2003) (153)
- Spectinamides: A New Class of Semisynthetic Anti-Tuberculosis Agents that Overcome Native Drug Efflux (2014) (148)
- Novel Insights into the Mechanism of Inhibition of MmpL3, a Target of Multiple Pharmacophores in Mycobacterium tuberculosis (2014) (146)
- Acyl-phosphates initiate membrane phospholipid synthesis in Gram-positive pathogens. (2006) (141)
- Globally Distributed Mycobacterial Fish Pathogens Produce a Novel Plasmid-Encoded Toxic Macrolide, Mycolactone F (2006) (119)
- A Newly Discovered Mycobacterial Pathogen Isolated from Laboratory Colonies of Xenopus Species with Lethal Infections Produces a Novel Form of Mycolactone, the Mycobacterium ulcerans Macrolide Toxin (2005) (118)
- Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis. (2007) (117)
- Synthesis of the Arabinose Donor .beta.-D-Arabinofuranosyl-1-monophosphoryldecaprenol, Development of a Basic Arabinosyl-Transferase Assay, and Identification of Ethambutol as an Arabinosyl Transferase Inhibitor (1995) (117)
- A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents. (2008) (100)
- A Pantothenate Kinase from Staphylococcus aureus Refractory to Feedback Regulation by Coenzyme A* (2005) (93)
- Inhibition of UDP-Gal Mutase and Mycobacterial Galactan Biosynthesis by Pyrrolidine Analogues of Galactofuranose (1997) (92)
- Use of stereocomplex crystallites for fully-biobased microcellular low-density poly(lactic acid) foams for green packaging (2017) (91)
- The structure-activity relationship of urea derivatives as anti-tuberculosis agents. (2011) (87)
- Discovery of novel selective inhibitors of human intestinal carboxylesterase for the amelioration of irinotecan-induced diarrhea: synthesis, quantitative structure-activity relationship analysis, and biological activity. (2004) (86)
- Acyl Carrier Protein Is a Cellular Target for the Antibacterial Action of the Pantothenamide Class of Pantothenate Antimetabolites* (2004) (84)
- A statistical framework to evaluate virtual screening (2009) (83)
- Liu F-NMR 19 by-Adrenergic Receptor Characterized 2 β Biased Signaling Pathways in (2012) (80)
- New approaches to target the mycolic acid biosynthesis pathway for the development of tuberculosis therapeutics. (2013) (79)
- Pantothenamides Are Potent, On-Target Inhibitors of Plasmodium falciparum Growth When Serum Pantetheinase Is Inactivated (2013) (77)
- Synthesis, Structure–Activity Relationship Studies, and Antibacterial Evaluation of 4-Chromanones and Chalcones, as Well as Olympicin A and Derivatives (2014) (77)
- Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents. (2004) (77)
- Synthesis and evaluation of cyclic secondary amine substituted phenyl and benzyl nitrofuranyl amides as novel antituberculosis agents. (2005) (76)
- Discovery of novel isoxazolines as anti-tuberculosis agents. (2007) (73)
- Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3 (2016) (73)
- Mechanisms involved in the intrinsic isoniazid resistance of Mycobacterium avium (1998) (72)
- Identification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy-d-xylo-4-hexopyranosid-4-ulose 3,5-epimerase (RmlC). (2010) (72)
- Rapid structural characterization of the arabinogalactan and lipoarabinomannan in live mycobacterial cells using 2D and 3D HR-MAS NMR: structural changes in the arabinan due to ethambutol treatment and gene mutation are observed. (2004) (71)
- Structural studies of pterin-based inhibitors of dihydropteroate synthase. (2009) (71)
- Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties. (2013) (68)
- Crystal structure of 7,8-dihydropteroate synthase from Bacillus anthracis: mechanism and novel inhibitor design. (2004) (68)
- Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability. (2012) (68)
- Structure-activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors. (2006) (64)
- Genome-wide expression profiling of the response to ciclopirox olamine in Candida albicans. (2005) (61)
- Synthesis, optimization and structure-activity relationships of 3,5-disubstituted isoxazolines as new anti-tuberculosis agents. (2009) (61)
- RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host (2017) (58)
- Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents. (2016) (56)
- Design, synthesis, and evaluation of novel ethambutol analogues. (2008) (56)
- Antibacterial and antitubercular activity of fosmidomycin, FR900098, and their lipophilic analogs. (2011) (55)
- A therapeutic approach to pantothenate kinase associated neurodegeneration (2018) (55)
- The Structure of the Pantothenate Kinase·ADP·Pantothenate Ternary Complex Reveals the Relationship between the Binding Sites for Substrate, Allosteric Regulator, and Antimetabolites* (2004) (54)
- In vitro pharmacokinetic/pharmacodynamic models in anti-infective drug development: focus on TB. (2010) (53)
- Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . (2010) (51)
- Discovery of non-carbohydrate inhibitors of aminoglycoside-modifying enzymes. (2005) (51)
- Multi-objective optimization of heat transfer mechanisms of microcellular polymeric foams from thermal-insulation point of view (2019) (50)
- N-substituted 3-acetyltetramic acid derivatives as antibacterial agents. (2008) (46)
- Nitrofurans as novel anti-tuberculosis agents: identification, development and evaluation. (2007) (44)
- The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations in Staphylococcus aureus Dihydropteroate Synthase (2018) (44)
- In vitro and in vivo Evaluation of Synergism between Anti-Tubercular Spectinamides and Non-Classical Tuberculosis Antibiotics (2015) (44)
- An approach to combinatorial library generation of galactofuranose mimics as potential inhibitors of mycobacterial cell wall biosynthesis: Synthesis of a peptidomimetic of uridine 5′-diphosphogalactofuranose (UDP-Galf) (1999) (44)
- Biopharmaceutics, pharmacokinetics and pharmacodynamics of antituberculosis drugs. (2008) (43)
- Synthesis of new and potent analogues of anti-tuberculosis agent 5-nitro-furan-2-carboxylic acid 4-(4-benzyl-piperazin-1-yl)-benzylamide with improved bioavailability. (2006) (43)
- Quantitative structure-activity relationship studies on nitrofuranyl anti-tubercular agents. (2008) (43)
- Detection of Mycolactone A/B in Mycobacterium ulcerans–Infected Human Tissue (2010) (42)
- Environmentally Friendly Polylactic Acid-Based Thermal Insulation Foams Blown with Supercritical CO2 (2018) (41)
- Covalent Modification of the Mycobacterium tuberculosis FAS-II Dehydratase by Isoxyl and Thiacetazone (2014) (40)
- Advancing Translational Science for Pulmonary Nontuberculous Mycobacterial Infections. A Road Map for Research (2019) (40)
- Antitubercular nitrofuran isoxazolines with improved pharmacokinetic properties. (2012) (38)
- Replacing sulfa drugs with novel DHPS inhibitors. (2013) (38)
- The membrane as a target for controlling hypervirulent Clostridium difficile infections. (2013) (37)
- Cytolethal distending toxin (2005) (37)
- Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis (2016) (37)
- Metabolic activation of CaMKII by coenzyme A. (2013) (37)
- A rapid approach to lipid profiling of mycobacteria using 2D HSQC NMR maps Published, JLR Papers in Press, November 2, 2007. (2008) (36)
- Novel Acyl Phosphate Mimics that Target PlsY, an Essential Acyltransferase in Gram‐Positive Bacteria (2008) (34)
- A simple in vitro PK/PD model system to determine time-kill curves of drugs against Mycobacteria. (2009) (34)
- Reutericyclin and related analogues kill stationary phase Clostridium difficile at achievable colonic concentrations. (2011) (33)
- Topology and Active Site of PlsY (2007) (33)
- Pharmacokinetically-Guided Lead Optimization of Nitrofuranylamide Anti-Tuberculosis Agents (2008) (33)
- Evaluation of Flavonoid and Resveratrol Chemical Libraries Reveals Abyssinone II as a Promising Antibacterial Lead (2012) (32)
- Thermoforming of Polylactic Acid Foam Sheets: Crystallization Behaviors and Thermal Stability (2016) (31)
- Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions. (2017) (30)
- Potentiation of Azole Antifungals by 2-Adamantanamine (2013) (30)
- Methods for acquisition and assignment of multidimensional high-resolution magic angle spinning NMR of whole cell bacteria. (2005) (29)
- Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs. (2021) (28)
- Study of the foaming mechanisms associated with gas counter pressure and mold opening using the pressure profiles (2017) (28)
- Gastrointestinal localization of metronidazole by a lactobacilli-inspired tetramic acid motif improves treatment outcomes in the hamster model of Clostridium difficile infection. (2015) (27)
- Structure‐Based Design of Novel Pyrimido[4,5‐c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity (2012) (26)
- Characterization of inhibitors of specific carboxylesterases: development of carboxylesterase inhibitors for translational application. (2004) (25)
- Solid-phase synthesis and biological evaluation of a uridinyl branched peptide urea library. (2007) (25)
- A Screen for and Validation of Prodrug Antimicrobials (2013) (25)
- Highly expanded fine-cell foam of polylactide/polyhydroxyalkanoate/nano-fibrillated polytetrafluoroethylene composites blown with mold-opening injection molding. (2020) (24)
- Synthesis and structure of mycolactone E isolated from frog mycobacterium. (2008) (24)
- Chemical Modulation of the Biological Activity of Reutericyclin: a Membrane-Active Antibiotic from Lactobacillus reuteri (2014) (24)
- Crystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensis (2010) (23)
- Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models (2016) (23)
- Analysis of Mycobacterium Species for the Presence of a Macrolide Toxin, Mycolactone (2004) (22)
- Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase. (2007) (22)
- Identification and Characterization of an Allosteric Inhibitory Site on Dihydropteroate Synthase (2014) (22)
- Aminomethyl Spectinomycins as Therapeutics for Drug-Resistant Gonorrhea and Chlamydia Coinfections (2018) (22)
- Allosteric Regulation of Mammalian Pantothenate Kinase* (2016) (22)
- Discovery, synthesis, and biological evaluation of piperidinol analogs with anti-tuberculosis activity. (2009) (21)
- Novel Inhibitors of an Emerging Target in Mycobacterium tuberculosis; Substituted Thiazolidinones as Inhibitors of dTDP‐Rhamnose Synthesis. (2003) (21)
- Applications of pharmacometrics in the clinical development and pharmacotherapy of anti-infectives (2013) (21)
- Evaluation of Analogs of Reutericyclin as Prospective Candidates for Treatment of Staphylococcal Skin Infections (2009) (21)
- Development of BODIPY FL Vindoline as a Novel and High-Affinity Pregnane X Receptor Fluorescent Probe (2014) (21)
- The Isoniazid Metabolites Hydrazine and Pyridoxal Isonicotinoyl Hydrazone Modulate Heme Biosynthesis (2018) (21)
- De Novo Design of Boron-Based Peptidomimetics as Potent Inhibitors of Human ClpP in the Presence of Human ClpX. (2019) (20)
- Fundamental Influences of Induced Crystallization and Phase Separation on the Foaming Behavior of Poly(lactic acid)/Polyethylene Glycol Blends Blown with Compressed CO2 (2016) (20)
- Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design (2017) (19)
- Translational PK/PD of anti-infective therapeutics. (2016) (19)
- SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A (2016) (19)
- Ureadepsipeptides as ClpP Activators. (2019) (19)
- Investigation of mechanical and morphological properties of acrylonitrile butadiene styrene nanocomposite foams from analytical hierarchy process point of view (2018) (19)
- Pentacyclic Nitrofurans with In Vivo Efficacy and Activity against Nonreplicating Mycobacterium tuberculosis (2014) (19)
- Synthesis and evaluation of pretomanid (PA-824) oxazolidinone hybrids. (2016) (19)
- In Vivo and In Vitro Effects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci (2018) (18)
- Design, Synthesis and Microbiological Evaluation of Ampicillin Tetramic acid Hybrid Antibiotics (2016) (17)
- Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors. (2018) (17)
- Activation of Exogenous Fatty Acids to Acyl-Acyl Carrier Protein Cannot Bypass FabI Inhibition in Neisseria* (2015) (17)
- Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies. (2003) (17)
- Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections (2015) (17)
- CINPA1 binds directly to constitutive androstane receptor and inhibits its activity (2018) (17)
- Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer (2020) (16)
- Novel Polyoxyethylene-Containing Glycolipids Are Synthesized in Corynebacterium matruchotii and Mycobacterium smegmatis Cultured in the Presence of Tween 80 (2010) (16)
- Development and Characterization of a Dry Powder Formulation for Anti-Tuberculosis Drug Spectinamide 1599 (2019) (15)
- Tensile and hardness properties of polycarbonate nanocomposites in the presence of styrene maleic anhydride as compatibilizer (2018) (15)
- Fabrication of electroactive poly(vinylidene fluoride) through non-isothermal crystallization and supercritical CO2 processing (2017) (15)
- Acyl-sulfamates target the essential glycerol-phosphate acyltransferase (PlsY) in Gram-positive bacteria. (2012) (15)
- Structural properties of batch foamed acrylonitrile butadiene styrene/nanoclay nanocomposites (2015) (14)
- Syntheses and evaluation of macrocyclic engelhardione analogs as antitubercular and antibacterial agents (2013) (14)
- Advances in Drug Discovery and Development for Pediatric Tuberculosis. (2016) (13)
- A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. (2022) (13)
- Synthesis and evaluation of esters and carbamates to identify critical functional groups for esterase-specific metabolism. (2003) (13)
- Synthesis of bi-substrate state mimics of dihydropteroate synthase as potential inhibitors and molecular probes. (2011) (13)
- Solid-Phase Synthesis and Antibacterial Activity of Cyclohexapeptide Wollamide B Analogs. (2018) (12)
- Pharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives (2018) (12)
- Solid-phase synthesis of a thymidinyl dipeptide urea library. (2007) (12)
- Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae (2020) (12)
- Phase II Metabolic Pathways of Spectinamide Antitubercular Agents: A Comparative Study of the Reactivity of 4-Substituted Pyridines to Glutathione Conjugation. (2016) (12)
- A Fluorescent Probe for Detecting Mycobacterium tuberculosis and Identifying Genes Critical for Cell Entry (2016) (12)
- Discovery and characterization of the antimetabolite action of thioacetamide-linked 1,2,3-triazoles as disruptors of cysteine biosynthesis in Gram-negative bacteria. (2019) (11)
- Improved expansion ratio and heat resistance of microcellular poly(L-lactide) foam via in-situ formation of stereocomplex crystallites (2018) (11)
- Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases (2020) (11)
- New β-lactam - Tetramic acid hybrids show promising antibacterial activities. (2018) (10)
- Development of a pterin-based fluorescent probe for screening dihydropteroate synthase. (2011) (10)
- Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens (2019) (9)
- Synthesis and Evaluation of Thiazolidine Amide and N‐Thiazolyl Amide Fluoroquinolone Derivatives (2017) (9)
- Solid-phase synthesis development of a thymidinyl and 2′-deoxyuridinyl Ugi library for anti-bacterial agent screening (2005) (8)
- In Vitro and In Vivo Activities of HPi1, a Selective Antimicrobial against Helicobacter pylori (2014) (8)
- The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase. (2014) (8)
- Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice. (2019) (8)
- Dynamic time‐kill curve characterization of spectinamide antibiotics 1445 and 1599 for the treatment of tuberculosis (2019) (7)
- Development of an etoposide prodrug for dual prodrug-enzyme antitumor therapy (2006) (7)
- 17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma (2020) (7)
- Lipid profiling using two-dimensional heteronuclear single quantum coherence NMR. (2009) (7)
- Discovery of novel bacterial elongation condensing enzyme inhibitors by virtual screening. (2014) (7)
- The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations inStaphylococcus aureusDihydropteroate Synthase. (2018) (7)
- Pharmacokinetic profile of spectinomycin in rats. (2013) (7)
- Pantothenate kinase activation relieves coenzyme A sequestration and improves mitochondrial function in mice with propionic acidemia (2021) (7)
- Synthesis and evaluation of colletoic acid core derivatives. (2016) (7)
- Mechanisms of resistance associated with the inhibition of the dehydration step of FAS-II in Mycobacterium tuberculosis. (2019) (6)
- Combating Multidrug‐Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling (2021) (5)
- Going Small: Using Biophysical Screening to Implement Fragment Based Drug Discovery (2016) (5)
- Azaindole Based Potentiator of Antibiotics against Gram-Negative Bacteria. (2021) (5)
- Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes. (2016) (5)
- Identification of Small Molecules Exhibiting Oxacillin Synergy through a Novel Assay for Inhibition of vraTSR Expression in Methicillin-Resistant Staphylococcus aureus (2019) (5)
- Exposure of Methicillin-Resistant Staphylococcus aureus to Low Levels of the Antibacterial THAM-3ΦG Generates a Small Colony Drug-Resistant Phenotype (2018) (5)
- Synthesis and antibacterial evaluation of macrocyclic diarylheptanoid derivatives. (2016) (5)
- Tissue Penetration of a Novel Spectinamide Antibiotic for the Treatment of Tuberculosis (2016) (5)
- Evaluating and evolving a screening library in academia: the St Jude approach. (2021) (4)
- Model-Based Exposure-Response Assessment for Spectinamide 1810 in a Mouse Model of Tuberculosis (2021) (4)
- Application of Optimization to Aircraft Engine Disk Synthesis (1981) (4)
- Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy against Tuberculosis. (2021) (4)
- The identification , analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7 , 8-dihydropterin pyrophosphokinase (2014) (4)
- Thermal-insulation performance of low density polyethylene (LDPE) foams: Comparison between two radiation thermal conductivity models (2018) (4)
- Small molecule SJ572946 activates BAK to initiate apoptosis (2022) (3)
- Dihydropteroate Synthetase From Bacillus anthracis (2004) (3)
- Structure‐Based Design, Synthesis, and Evaluation of 2′‐(2‐Hydroxyethyl)‐2′‐deoxyadenosine and the 5′‐Diphosphate Derivative as Ribonucleotide Reductase Inhibitors (2009) (3)
- A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance (2022) (3)
- Efficacy of Aminomethyl Spectinomycins against Complex Upper Respiratory Tract Bacterial Infections (2019) (3)
- E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity. (2023) (2)
- Development of BODIPY FL Thalidomide As a High-Affinity Fluorescent Probe for Cereblon in a Time-Resolved Fluorescence Resonance Energy Transfer Assay. (2020) (2)
- LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators (2021) (2)
- Replacement of S14 Protein in Ribosomes of Zinc-Starved Mycobacteria Reduces Spectinamide Sensitivity (2020) (2)
- Targeting Helicobacter pylori for antibacterial drug discovery with novel therapeutics. (2022) (2)
- Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology (2012) (2)
- 1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis (2022) (2)
- Erratum to Metabolic Activation of CaMKII by Coenzyme A [(Molecular Cell, 52, (2013), 327-341] (2013) (2)
- The Discovery and Development of Thienopyrimidines as Inhibitors of Helicobacter pylori That Act through Inhibition of the Respiratory Complex I. (2021) (2)
- Synthesis and Structure–Activity Relationship of Thioacetamide-Triazoles against Escherichia coli (2022) (2)
- Identification of Inhibitors of Fungal Fatty Acid Biosynthesis (2021) (2)
- Picture Polar Science: Using Gigapan to Connect Classrooms to Antarctic Cryobiologists (2010) (1)
- Relief of CoA sequestration and restoration of mitochondrial function in a mouse model of propionic acidemia (2022) (1)
- Mechanistic insight on the mode of action of colletoic acid. (2019) (1)
- High‐Throughput Solid‐Phase Synthesis of Nucleoside‐Based Libraries in the Search for New Antibiotics (2009) (1)
- Development of an N-Terminal BRD4 Bromodomain-Targeted Degrader. (2021) (1)
- Mab2780c, a TetV-like efflux pump, confers high-level spectinomycin resistance in mycobacterium abscessus. (2022) (1)
- Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs (2021) (1)
- Structure − Activity Relationships of Spectinamide Antituberculosis Agents : A Dissection of Ribosomal Inhibition and Native E ffl ux Avoidance Contributions (2017) (1)
- A Tribute to Amy Anderson (1969-2016): Leader, Role Model, and Advocate for Structure-Based Design of New Antimicrobial Agents. (2016) (1)
- Organic Reactions. Volume 73 Organic Reactions. Volume 73 . Edited by S. E. Denmark. John Wiley and Sons , New York . 2009 . vii + 607 pp. 16 × 24 cm. ISBN 0470436905 . $140.00. (2009) (0)
- THE STRUCTURE GUIDED SYNTHESIS OF RHAMNOSE BIOSYNTHESIS INHIBITORS (2002) (0)
- Review Combating Resistan C e: infe C tious Diseases (2013) (0)
- Abstract 1907: Combocat: A high-throughput framework for drug combination studies (2022) (0)
- Crystal Structure of E. coli Pantothenate kinase (2004) (0)
- Mycobacteria and Macrolide-mediated Virulence in Human and Frogs (2005) (0)
- Synthesis of New and Potent Analogues of anti‐Tuberculosis Agent 5‐Nitro‐furan‐2‐carboxylic Acid 4‐(4‐Benzyl‐piperazin‐1‐yl)‐benzylamide with Improved Bioavailability. (2006) (0)
- A therapeutic approach to pantothenate kinase associated neurodegeneration (2018) (0)
- Optimization of solid and radiation thermal conductivity of polymeric foams using response surface method based on a novel theoretical model (2019) (0)
- Exposure of Methicillin-Resistant Staphylococcus aureus to Low Levels of the Antibacterial THAM-3ΦG Generates a Small Colony Drug-Resistant Phenotype (2018) (0)
- Discovery and Development of Allosteric Pantothenate Kinase Activators (2017) (0)
- Distributed Mycobacterial Fish Pathogens Produce a Novel Plasmid-Encoded Toxic Macrolide, Mycolactone F (cid:1) (2006) (0)
- Detection of mycolactone by mass spectrometry. (2013) (0)
- Winners of the 2021 JA Ōmura Awards for excellence (2022) (0)
- Dihydropteroate Synthetase, With Bound Substrate Analogue PtPP, From Bacillus anthracis (2004) (0)
- Synthesis, antibacterial action, and ribosome inhibition of deoxyspectinomycins (2021) (0)
- Crystal structure of the second bromodomain of human BRD2 in complex with a tetrahydroquinoline inhibitor (2018) (0)
- Inhibition of UDP‐Gal Mutase and Mycobacterial Galactan Biosynthesis by Pyrrolidine Analogues of Galactofuranose. (1997) (0)
- Geldanamycin inhibits Jumonji histone lysine demethylase KDM4 and targets chimeric transcription factor PAX3-FOXO1 (2019) (0)
- Metabolic regulation of apoptosis via coenzyme A mediated activation of CaMKII (577.2) (2014) (0)
- Dihydropteroate Synthetase, With Bound Inhibitor MANIC, From Bacillus anthracis (2004) (0)
- Winners of the 2020 JA Ōmura Awards for excellence (2022) (0)
- Novel Insights into the Mechanism of Inhibition of MmpL3, a Target of Multiple 1 (2014) (0)
- 1233. Identification of Novel Inhibitors of Clostridioides difficile Enoyl-Reductase II (FabK) by High-Throughput Virtual and Experimental Screening (2020) (0)
- Fragment-Based Approach Identifies a Novel Inhibitory Site on DHPS (2013) (0)
- Preclinical in vivo assessment of replacing linezolid for spectinamide-1599 in the Nix-TB regimen (2022) (0)
- The licorice metabolite enoxolone attenuates Clostridioides difficile pathophysiology by corrupting its metabolic and toxin production networks (2022) (0)
- Amides heterocycliques a activite anti-tuberculinique (2004) (0)
- In Vitro and In Vivo Activities of HPi 1 , a Selective Antimicrobial against Helicobacter pylori (2014) (0)
- Identifi ' cation of the apparent carrier in mycolic acid synthesis ( mycobacteria / 6-0-mycolyl-mannosyl-1-phosphopolyprenol / antituberculosis drugs ) (2005) (0)
- Dihydropteroate Synthetase, With Bound Product Analogue Pteroic Acid, From Bacillus anthracis (2004) (0)
- Winners of the 2019 JA Ōmura Awards for excellence (2019) (0)
- RV3666c bound to tripeptide (2021) (0)
- Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens (2019) (0)
- Editorial overview: Recent advances in antimicrobial drug discovery and resistance. (2022) (0)
- Characterization of spectinamide 1599 efficacy against different mycobacterial phenotypes. (2023) (0)
- Tissue Penetration of a Novel Spectinamide Antibiotic for the Treatment of Tuberculosis (2016) (0)
- Physiological Model-Based Prediction of the Human Pharmacokinetics of Lee1599, a Novel Anti-tuberculosis Agent (2013) (0)
- Pharmacokinetic Evaluation of Novel Amino-Spectinomycin Antibiotics (2014) (0)
- Lack of Specificity of Phenotypic Screens for Inhibitors of the Mycobacterium tuberculosis FAS-II System (2020) (0)
- Angioinvasive mucormycosis in a patient with aplastic anemia (2022) (0)
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