Richard A. Lempicki
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Computer Science
Richard A. Lempicki's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Richard A. Lempicki's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources (2008) (30984)
- Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists (2008) (12905)
- DAVID: Database for Annotation, Visualization, and Integrated Discovery (2003) (8250)
- The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists (2007) (2032)
- Identifying biological themes within lists of genes with EASE (2003) (2015)
- DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists (2007) (1836)
- DAVID: Database for Annotation, Visualization, and Integrated Discovery (2003) (1141)
- DAVID-WS: a stateful web service to facilitate gene/protein list analysis (2012) (830)
- HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression. (1999) (788)
- Evaluation of gene expression measurements from commercial microarray platforms. (2003) (751)
- DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis (2007) (495)
- Extracting Biological Meaning from Large Gene Lists with DAVID (2009) (415)
- HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells (2008) (373)
- Evidence for Increased T Cell Turnover and Decreased Thymic Output in HIV Infection1 (2001) (280)
- Identification of Dynamically Distinct Subpopulations of T Lymphocytes That Are Differentially Affected by HIV (2001) (244)
- Cutting Edge: Ku70 Is a Novel Cytosolic DNA Sensor That Induces Type III Rather Than Type I IFN (2011) (227)
- PubMatrix: a tool for multiplex literature mining (2003) (217)
- Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4+ and CD8+ T cell turnover in HIV-infected patients. (2000) (209)
- Gene expression and viral prodution in latently infected, resting CD4+ T cells in viremic versus aviremic HIV-infected individuals (2003) (180)
- HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication (2002) (177)
- DAVID gene ID conversion tool (2008) (167)
- Evidence for innate immune system activation in HIV type 1-infected elite controllers. (2014) (142)
- Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients. (2005) (134)
- Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts (2016) (126)
- Cutting Edge: L-Selectin (CD62L) Expression Distinguishes Small Resting Memory CD4+ T Cells That Preferentially Respond to Recall Antigen (2003) (123)
- Safety, tolerability, and mechanisms of antiretroviral activity of pegylated interferon Alfa-2a in HIV-1-monoinfected participants: a phase II clinical trial. (2010) (111)
- Noninfectious papilloma virus-like particles inhibit HIV-1 replication: implications for immune control of HIV-1 infection by IL-27. (2007) (103)
- IL-2-induced CD4+ T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation. (2004) (102)
- Nonalcoholic Steatohepatitis and Hepatic Fibrosis in HIV-1-Monoinfected Adults With Elevated Aminotransferase Levels on Antiretroviral Therapy. (2015) (100)
- Comparison of mRNA and Protein Measures of Cytokines following Vaccination with Human Papillomavirus-16 L1 Virus-like Particles (2010) (99)
- Human Immunodeficiency Virus Viremia Induces Plasmacytoid Dendritic Cell Activation In Vivo and Diminished Alpha Interferon Production In Vitro (2008) (91)
- IL-27, a novel anti-HIV cytokine, activates multiple interferon-inducible genes in macrophages (2008) (90)
- Functional Genomics of Innate Host Defense Molecules in Normal Human Monocytes in Response to Aspergillus fumigatus (2006) (87)
- Identification and functional clustering of global gene expression differences between human age-related cataract and clear lenses. (2003) (79)
- Innate Immune Dysfunction in HIV Infection: Effect of HIV Envelope-NK Cell Interactions12 (2006) (79)
- HIV-1 gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression (2013) (77)
- Diminished Production of Monocyte Proinflammatory Cytokines during Human Immunodeficiency Virus Viremia Is Mediated by Type I Interferons (2006) (74)
- Naïve T-Cell Dynamics in Human Immunodeficiency Virus Type 1 Infection: Effects of Highly Active Antiretroviral Therapy Provide Insights into the Mechanisms of Naïve T-Cell Depletion (2006) (71)
- Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B‐unfavorable genotype patients: Impaired viral kinetics and therapeutic response (2012) (70)
- Gene duplications in prokaryotes can be associated with environmental adaptation (2010) (70)
- Increased peripheral expansion of naive CD4+ T cells in vivo after IL-2 treatment of patients with HIV infection (2002) (69)
- Gene expression profiles in hepatitis C virus (HCV) and HIV coinfection: class prediction analyses before treatment predict the outcome of anti-HCV therapy among HIV-coinfected persons. (2006) (69)
- R5 and X4 HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells. (2006) (68)
- Evolution of the Pygmy Phenotype: Evidence of Positive Selection from Genome-wide Scans in African, Asian, and Melanesian Pygmies (2013) (67)
- IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation (2013) (65)
- A Benchmark Study on Error Assessment and Quality Control of CCS Reads Derived from the PacBio RS. (2013) (65)
- Long homopurine•homopyrimidine sequences are characteristic of genes expressed in brain and the pseudoautosomal region (2006) (59)
- Interleukin‐2 induced immune effects in human immunodeficiency virus‐infected patients receiving intermittent interleukin‐2 immunotherapy (2001) (57)
- Lifespan of effector memory CD4+ T cells determined by replication-incompetent integrated HIV-1 provirus (2014) (53)
- Human immunodeficiency virus and hepatitis C infections induce distinct immunologic imprints in peripheral mononuclear cells (2009) (51)
- The effects of storage temperature on PBMC gene expression (2016) (51)
- HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells. (2006) (50)
- Differential effects of HIV viral load and CD4 count on proliferation of naive and memory CD4 and CD8 T lymphocytes. (2011) (47)
- HIV infection and antiretroviral therapy have divergent effects on mitochondria in adipose tissue. (2012) (45)
- Interleukin-27 Is a Potent Inhibitor of cis HIV-1 Replication in Monocyte-Derived Dendritic Cells via a Type I Interferon-Independent Pathway (2013) (43)
- Interleukin-27 treated human macrophages induce the expression of novel microRNAs which may mediate anti-viral properties. (2013) (43)
- Innate Immunity in HIV Infection: Enhanced Susceptibility to CD95-Mediated Natural Killer Cell Death and Turnover Induced by HIV Viremia (2007) (42)
- Sequencing and characterization of the complete mitochondrial genomes of three Pneumocystis species provide new insights into divergence between human and rodent Pneumocystis (2013) (37)
- Defective plasmacytoid dendritic cell-NK cell cross-talk in HIV infection. (2009) (35)
- CCL5: A Double-Edged Sword in Host Defense Against the Hepatitis C Virus (2011) (33)
- Oligonucleotide Microarray Data Distribution And Normalization (2002) (33)
- Retinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux (2012) (31)
- Differential Gene and MicroRNA Expression between Etoposide Resistant and Etoposide Sensitive MCF7 Breast Cancer Cell Lines (2012) (30)
- LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes (2011) (29)
- Saccharomyces cerevisiae U14 small nuclear RNA has little secondary structure and appears to be produced by post-transcriptional processing. (1994) (28)
- Safety , Tolerability , and Mechanisms of Antiretroviral Activity of Pegylated Interferon Alfa-2 a in HIV-1 – Monoinfected Participants : A Phase II Clinical Trial (2010) (27)
- Association of interleukin-15-induced peripheral immune activation with hepatic stellate cell activation in persons coinfected with hepatitis C virus and HIV. (2009) (27)
- β-Glucans Are Masked but Contribute to Pulmonary Inflammation During Pneumocystis Pneumonia. (2016) (25)
- Towards Better Precision Medicine: PacBio Single-Molecule Long Reads Resolve the Interpretation of HIV Drug Resistant Mutation Profiles at Explicit Quasispecies (Haplotype) Level (2015) (25)
- Host gene expression changes correlating with anti-HIV-1 effects in human subjects after treatment with peginterferon Alfa-2a. (2012) (24)
- HIV envelope-directed signaling aberrancies and cell death of CD4+ T cells in the absence of TCR co-stimulation. (1996) (24)
- Pre-gastrula expression of zebrafish extraembryonic genes (2010) (24)
- Comparative Population Genomics Analysis of the Mammalian Fungal Pathogen Pneumocystis (2018) (23)
- The CD8+HLA‐DR+ T cells expanded in HIV‐1 infection are qualitatively identical to those from healthy controls (2012) (23)
- Telomere length and heavy-chain mutation status in familial chronic lymphocytic leukemia. (2002) (22)
- CD4 T cell survival after intermittent interleukin-2 therapy is predictive of an increase in the CD4 T cell count of HIV-infected patients. (2008) (21)
- Actinomycin D Induces High-Level Resistance to Thymidine Analogs in Replication of Human Immunodeficiency Virus Type 1 by Interfering with Host Cell Thymidine Kinase Expression (2003) (21)
- Identification and characterization of rapidly dividing U937 clones with differential telomerase activity and gene expression profiles: role of c-Myc/Mad1 and Id/Ets proteins (2002) (20)
- General Immunologic Evaluation of Patients with Human Immunodeficiency Virus Infection (2006) (19)
- Twice-weekly pegylated interferon-α-2a and ribavirin results in superior viral kinetics in HIV/hepatitis C virus co-infected patients compared to standard therapy (2011) (17)
- Escherichia coli 4.5S RNA gene function can be complemented by heterologous bacterial RNA genes (1990) (17)
- Gene Expression Patterns Induced by HPV-16 L1 Virus-Like Particles in Leukocytes from Vaccine Recipients1 (2009) (16)
- Zap70 Signaling Pathway Mediates Glucocorticoid Receptor-Dependent Transcriptional Activation: Role in the Regulation of Annexin 1 Expression in T Cells1 (2007) (14)
- Interleukin-27 induces interferon-inducible genes: analysis of gene expression profiles using Affymetrix microarray and DAVID. (2012) (14)
- High interferon‐stimulated gene ISG‐15 expression affects HCV treatment outcome in patients co‐infected with HIV and HCV (2013) (13)
- Identifying biological themes within lists of genes with EASE (2003) (13)
- Interleukin-2 Inhibits HIV-1 Replication in Some Human T Cell Lymphotrophic Virus-1-infected Cell Lines via the Induction and Incorporation of APOBEC3G into the Virion* (2013) (13)
- Retinoic acid-induced downmodulation of telomerase activity in human cancer cells. (2005) (12)
- Identification of novel markers for liver fibrosis in HIV/hepatitis C virus coinfected individuals using genomics-based approach (2008) (12)
- A comparison of microLC/electrospray ionization-MS and GC/MS for the measurement of stable isotope enrichment from a [2H2]-glucose metabolic probe in T-cell genomic DNA. (2003) (9)
- Altered expression of SHIP, a Toll-like receptor pathway inhibitor, is associated with the severity of liver fibrosis in chronic hepatitis C virus infection. (2011) (9)
- Altered regulation of extrinsic apoptosis pathway in HCV‐infected HCC cells enhances susceptibility to mapatumumab‐induced apoptosis (2009) (9)
- Gene Expression Profiles in a Rabbit Model of Systemic Lupus Erythematosus Autoantibody Production (2010) (8)
- Cytokine/chemokine patterns connect host and viral characteristics with clinics during chronic hepatitis C (2012) (8)
- Gene Expression Profiles Predict Emergence of Psychiatric Adverse Events in HIV/HCV-Coinfected Patients on Interferon-Based HCV Therapy (2012) (7)
- Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple Pneumocystis Species (2020) (7)
- Differential Specificity of Interferon-alpha Inducible Gene Expression in Association with Human Immunodeficiency Virus and Hepatitis C Virus Levels and Declines in vivo. (2015) (7)
- Hepatic histologic response (HR) to combination therapy among HCV/HIV-coinfected individuals: interferon induces HR independent of sustained virologic response (SVR). (2006) (6)
- Interferon stimulated exonuclease gene 20 kDa links psychiatric events to distinct hepatitis C virus responses in human immunodeficiency virus positive patients (2014) (6)
- Hepatitis C-Associated Mixed Cryoglobulinemic Vasculitis Induces Differential Gene Expression in Peripheral Mononuclear Cells (2014) (6)
- Naı¨ve T-Cell Dynamics in Human Immunodeficiency Virus Type 1 Infection: Effects of Highly Active Antiretroviral Therapy Provide Insights into the Mechanisms of Naı¨ve T-Cell Depletion (2006) (5)
- Characterization of chemokine and chemokine receptor expression during Pneumocystis infection in healthy and immunodeficient mice. (2015) (5)
- Mutations in conserved domains of U14 RNA impair 18S ribosomal RNA production in Saccharomyces cerevisiae (2004) (3)
- Clearance of Pneumocystis murina infection is not dependent on MyD88. (2014) (3)
- Comparative efficacy, pharmacokinetic, pharmacodynamic activity, and interferon stimulated gene expression of different interferon formulations in HIV/HCV genotype‐1 infected patients (2014) (3)
- 077 PBMC gene expression profiles: Impact of sample handling (2013) (2)
- Ku70 is a novel cytosolic DNA sensor that induces a Type-III rather than Type-I IFN via activation of IRF-1 and IRF-7. (116.11) (2011) (2)
- SS4-4 Ku70 is a novel cytosolic DNA sensor and induces type-III IFN rather than Type-I IFN (2010) (2)
- 1334 DYSREGULATION OF HOST INNATE IMMUNITY IN HCV GENOTYPE 1 INFECTED IL28B CT/TT HAPLOTYPE PATIENTS WITH DEPRESSED VIRAL KINETICS AND THERAPEUTIC RESPONSE (2011) (2)
- Correction: LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes (2012) (1)
- Diversity and complexity of the large surface protein family in the compacted genomes of various Pneumocystis species (2019) (1)
- Retinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux (2012) (1)
- Transcriptomic response to differentiation induction (2006) (1)
- CD4 T Cell Survival Following Intermittent IL-2 Therapy is Predictive of Increase in CD4 T Cell Count in HIV-Infected Patients (2009) (1)
- HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells (2006) (1)
- Antigen RecallT Cells That Preferentially Respond to + Distinguishes Small Resting Memory CD 4 Cutting Edge : L-Selectin ( CD 62 L ) Expression Lempicki (2002) (1)
- Gene expression patterns induced by HPV‐16 L1 VLP in leukocytes from vaccine recipients (2008) (1)
- Connecting the dots on interferon responsiveness in HCV/HIV co-infection: The virus, the cytokine, the receptor and the gene (2009) (0)
- The effects of storage temperature on PBMC gene expression (2016) (0)
- Human Immunodeficiency Virus Viremia Induces Plasmacytoid Dendritic Cell Activation In Vivo and Diminished Alpha Interferon Production In Vitro (cid:1) (2008) (0)
- 324 IL-27 is a novel anti-viral cytokine that inhibits replication of HIV-1 and HCV (2008) (0)
- PS3-50 Differential transcriptosome profiles and antiviral effect of interferon-λ and interferon-α on HCV-infected and uninfected hepatoma cells (2010) (0)
- 045 Bioinformatics approach in cryopreservation (2013) (0)
- Regulation of Annexin 1 Expression in T Transcriptional Activation : Role in the Glucocorticoid Receptor-Dependent Zap 70 Signaling Pathway Mediates and (2007) (0)
- Than Type I IFN DNA Sensor That Induces Type III Rather Cutting Edge : Ku 70 Is a Novel Cytosolic and Tomozumi Imamichi (2011) (0)
- A search for cellular components that interact with the U14 small nucleolar RNA of yeast (1994) (0)
- InteractionsInfection: Effect of HIV Envelope-NK Cell Innate Immune Dysfunction in HIV (2005) (0)
- Non-infectious Papilloma virus – like Particles Inhibit HIV-1 Replication : Implications for Immune Control of HIV-1 Infection by IL-27 Short title : IL-27 inhibits HIV-1 replication (2006) (0)
- Realign PacBio reads to improve variant call performance (2014) (0)
- Distinguishing highly similar gene isoforms with a clustering-based bioinformatics analysis of PacBio single-molecule long reads (2016) (0)
- Immunodeficiency and intrinsic IFN resistance are associated with viral breakthrough to HCV therapy in HIV-coinfected patients. (2007) (0)
- I IFN Sensor That Induces Type III Rather Than Type Cutting Edge: Ku70 Is a Novel Cytosolic DNA (2011) (0)
- Decreased Thymic Output in HIV Infection Evidence for Increased T Cell Turnover and (2001) (0)
- Autoantibody Production of Systemic Lupus Erythematosus Gene Expression Profiles in a Rabbit Model (2010) (0)
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