Richard I. Morimoto

Richard I. Morimoto's AcademicInfluence.com Rankings

Richard I. Morimoto

Biology

#2537

World Rank

#4009

Historical Rank

#1134

USA Rank

Cell Biology

#63

World Rank

#67

Historical Rank

#28

USA Rank

Molecular Biology

#197

World Rank

#201

Historical Rank

#92

USA Rank

biology Degrees

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Biology

Why Is Richard I. Morimoto Influential?

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According to Wikipedia, Richard I. Morimoto is a Japanese American molecular biologist. He is the Bill and Gayle Cook Professor of Biology and Director of the Rice Institute for Biomedical Research at Northwestern University.

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Richard I. Morimoto's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Adapting Proteostasis for Disease Intervention (2008) (2080)
Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. (1998) (1869)
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome (2000) (1496)
1 Progress and Perspectives on the Biology of Heat Shock Proteins and Molecular Chaperones (1994) (1470)
Cells in stress: transcriptional activation of heat shock genes. (1993) (1428)
Geroscience: Linking Aging to Chronic Disease (2014) (1391)
Heat shock factors: integrators of cell stress, development and lifespan (2010) (1199)
Biological and chemical approaches to diseases of proteostasis deficiency. (2009) (1066)
Role of the heat shock response and molecular chaperones in oncogenesis and cell death. (2000) (1042)
The biology of proteostasis in aging and disease. (2015) (971)
Activation of Heat Shock Gene Transcription by Heat Shock Factor 1 Involves Oligomerization, Acquisition of DNA-Binding Activity, and Nuclear Localization and Can Occur in the Absence of Stress (1993) (886)
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging. (2008) (873)
Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70. (1985) (801)
Stress proteins in biology and medicine (1990) (782)
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans (2002) (764)
The Chaperone Function of hsp70 Is Required for Protection against Stress-Induced Apoptosis (2000) (745)
Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones. (2003) (726)
Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1 (2009) (682)
Chaperoning signaling pathways: molecular chaperones as stress-sensing 'heat shock' proteins. (2002) (659)
Stress–inducible responses and heat shock proteins: New pharmacologic targets for cytoprotection (1998) (654)
Molecular chaperones as HSF1-specific transcriptional repressors. (1998) (648)
Progressive Disruption of Cellular Protein Folding in Models of Polyglutamine Diseases (2006) (628)
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging (2009) (604)
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span (2017) (579)
The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression. (1992) (544)
Molecular chaperones and the stress of oncogenesis (2004) (539)
BAG‐1 modulates the chaperone activity of Hsp70/Hsc70 (1997) (513)
Heat Shock Response Modulators as Therapeutic Tools for Diseases of Protein Conformation* (2005) (484)
The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones. (1997) (446)
Structure and expression of the human gene encoding major heat shock protein HSP70 (1985) (433)
Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation. (2004) (427)
The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj‐1 have distinct roles in recognition of a non‐native protein and protein refolding. (1996) (419)
Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells. (1988) (414)
Celastrols as Inducers of the Heat Shock Response and Cytoprotection*[boxs] (2004) (413)
Effect of sodium salicylate on the human heat shock response. (1992) (413)
A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease. (2014) (403)
Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans. (2000) (394)
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia (2020) (391)
Transcriptional regulation of heat shock genes. A paradigm for inducible genomic responses. (1992) (389)
HSF4, a new member of the human heat shock factor family which lacks properties of a transcriptional activator (1997) (381)
Molecular Chaperone Machines: Chaperone Activities of the Cyclophilin Cyp-40 and the Steroid Aporeceptor-Associated Protein p23 (1996) (373)
The heat shock response: systems biology of proteotoxic stress in aging and disease. (2011) (371)
Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability. (1991) (371)
Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1 (2001) (349)
Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation (1997) (335)
Regulation of the Cellular Heat Shock Response in Caenorhabditis elegans by Thermosensory Neurons (2008) (332)
Stress-Inducible Cellular Responses (1996) (331)
Widespread Proteome Remodeling and Aggregation in Aging C. elegans (2015) (328)
Activation of Heat Shock Factor 1 DNA Binding Precedes Stress-induced Serine Phosphorylation (1996) (316)
1 The Stress Response, Function of the Proteins, and Perspectives (1990) (313)
Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemia cells (1992) (309)
Widespread Proteome Remodeling and Aggregation in Aging C. elegans (2017) (304)
Polyglutamine protein aggregates are dynamic (2002) (303)
Expression of human HSP70 during the synthetic phase of the cell cycle. (1986) (301)
Huntington's disease: underlying molecular mechanisms and emerging concepts. (2013) (295)
Bag1–Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth (2001) (289)
In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation. (1990) (289)
Inefficient degradation of truncated polyglutamine proteins by the proteasome (2004) (287)
Human HSP70 promoter contains at least two distinct regulatory domains. (1986) (278)
Metazoan Hsp70 machines use Hsp110 to power protein disaggregation (2012) (278)
Human heat shock factors 1 and 2 are differentially activated and can synergistically induce hsp70 gene transcription (1994) (277)
Characterization of a novel chicken heat shock transcription factor, heat shock factor 3, suggests a new regulatory pathway (1993) (277)
Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state (2006) (267)
Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation (2015) (267)
Posttranscriptional regulation of hsp70 expression in human cells: effects of heat shock, inhibition of protein synthesis, and adenovirus infection on translation and mRNA stability (1987) (252)
Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction. (2015) (230)
Proteostasis and the aging proteome in health and disease. (2014) (228)
Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule. (2007) (228)
Complex regulation of heat shock- and glucose-responsive genes in human cells (1988) (227)
Negative regulation of the heat shock transcriptional response by HSBP1. (1998) (223)
Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins. (2013) (221)
The stress of protein misfolding: from single cells to multicellular organisms. (2011) (219)
Transcription of the human hsp70 gene is induced by serum stimulation. (1985) (218)
Cdc37 is a molecular chaperone with specific functions in signal transduction. (1997) (215)
Triptolide, an Inhibitor of the Human Heat Shock Response That Enhances Stress-induced Cell Death* (2006) (214)
Small Molecule Proteostasis Regulators for Protein Conformational Diseases (2011) (213)
Arachidonate is a potent modulator of human heat shock gene transcription. (1994) (207)
Autophagy in healthy aging and disease (2021) (205)
Attenuation of the heat shock response in HeLa cells is mediated by the release of bound heat shock transcription factor and is modulated by changes in growth and in heat shock temperatures. (1991) (200)
Heat Shock Response and Protein Degradation: Regulation of HSF2 by the Ubiquitin-Proteasome Pathway (1998) (195)
Dynamic Remodeling of Transcription Complexes by Molecular Chaperones (2002) (194)
Antiproliferative prostaglandins activate heat shock transcription factor. (1992) (192)
Cloning and Subcellular Localization of Human Mitochondrial hsp70 (*) (1995) (190)
The transcriptional regulation of heat shock genes: a plethora of heat shock factors and regulatory conditions. (1996) (188)
Pharmacological modulation of heat shock factor 1 by antiinflammatory drugs results in protection against stress-induced cellular damage. (1995) (187)
Expression of heat shock factor 2 in mouse testis: potential role as a regulator of heat-shock protein gene expression during spermatogenesis. (1994) (187)
Destabilizing Protein Polymorphisms in the Genetic Background Direct Phenotypic Expression of Mutant SOD1 Toxicity (2009) (187)
Regulation of Organismal Proteostasis by Transcellular Chaperone Signaling (2013) (179)
Polyglutamine Proteins at the Pathogenic Threshold Display Neuron-Specific Aggregation in a Pan-Neuronal Caenorhabditis elegans Model (2006) (179)
BAG‐1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release (1998) (176)
Protein homeostasis and aging: taking care of proteins from the cradle to the grave. (2009) (175)
Stress-induced activation of the heat-shock response: cell and molecular biology of heat-shock factors. (1999) (174)
Rethinking HSF1 in Stress, Development, and Organismal Health. (2017) (174)
Studies of cloned sequences from four drosophila heat shock loci (1979) (173)
HSF1 granules: a novel stress-induced nuclear compartment of human cells. (1997) (170)
Chaperone networks: Tipping the balance in protein folding diseases (2010) (170)
Mutational analysis of the human HSP70 protein: distinct domains for nucleolar localization and adenosine triphosphate binding (1989) (169)
Mitogen and lymphokine stimulation of heat shock proteins in T lymphocytes. (1988) (168)
Shaping proteostasis at the cellular, tissue, and organismal level (2017) (164)
Heat shock-induced interactions of heat shock transcription factor and the human hsp70 promoter examined by in vivo footprinting (1991) (163)
Structural properties and neuronal toxicity of amyotrophic lateral sclerosis–associated Cu/Zn superoxide dismutase 1 aggregates (2005) (162)
Heat shock: the role of transient inducible responses in cell damage, transformation, and differentiation. (1991) (161)
Protein homeostasis in models of aging and age-related conformational disease. (2010) (157)
Selection of new HSF1 and HSF2 DNA-binding sites reveals difference in trimer cooperativity (1994) (154)
Role of the Heat‐Shock Response in the Life and Death of Proteins (1998) (153)
Two transcriptional activators, CCAAT-box-binding transcription factor and heat shock transcription factor, interact with a human hsp70 gene promoter (1987) (152)
Cell cycle-dependent association of HSP70 with specific cellular proteins (1989) (151)
Sequence homologies in the 5' regions of four Drosophila heat-shock genes. (1981) (149)
Large-scale investigation of the reasons why potentially important genes are ignored (2018) (147)
Function and regulation of heat shock factor 2 during mouse embryogenesis. (1997) (147)
Mutations in the substrate binding domain of the Escherichia coli 70 kDa molecular chaperone, DnaK, which alter substrate affinity or interdomain coupling. (1999) (144)
The carboxyl-terminal transactivation domain of heat shock factor 1 is negatively regulated and stress responsive (1995) (143)
Investigating the spreading and toxicity of prion-like proteins using the metazoan model organism C. elegans. (2015) (143)
The nascent polypeptide‐associated complex is a key regulator of proteostasis (2013) (141)
In vivo binding of active heat shock transcription factor 1 to human chromosome 9 heterochromatin during stress (2002) (141)
Bag1 Functions In Vivo as a Negative Regulator of Hsp70 Chaperone Activity (2000) (139)
E1a transactivation of the human HSP70 promoter is mediated through the basal transcriptional complex (1989) (138)
Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins (2011) (137)
Rapid and reversible relocalization of heat shock factor 1 within seconds to nuclear stress granules. (1999) (136)
Four heat shock proteins of Drosophila melanogaster coded within a 12-kilobase region in chromosome subdivision 67B. (1980) (136)
The Cellular Inhibitor of the PKR Protein Kinase, P58IPK, Is an Influenza Virus-activated Co-chaperone That Modulates Heat Shock Protein 70 Activity* (1999) (136)
Supersaturation is a major driving force for protein aggregation in neurodegenerative diseases. (2015) (135)
Integrating the stress response: lessons for neurodegenerative diseases from C. elegans. (2009) (135)
Maximal stress-induced transcription from the human HSP70 promoter requires interactions with the basal promoter elements independent of rotational alignment (1990) (134)
Human Hsp70 molecular chaperone binds two calcium ions within the ATPase domain. (1997) (134)
Neuronal Serotonin Release Triggers the Heat Shock Response in C. elegans in the Absence of Temperature Increase (2015) (129)
Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition (2014) (129)
Heat shock-induced translational control of HSP70 and globin synthesis in chicken reticulocytes (1984) (125)
Disruption of the HSF3 gene results in the severe reduction of heat shock gene expression and loss of thermotolerance (1998) (124)
Regulatory differences in the stress response of hippocampal neurons and glial cells after heat shock (1996) (122)
Huntingtin and Mutant SOD1 Form Aggregate Structures with Distinct Molecular Properties in Human Cells* (2006) (122)
HSF1 transcription factor concentrates in nuclear foci during heat shock: relationship with transcription sites. (1997) (122)
Stress-Specific Activation and Repression of Heat Shock Factors 1 and 2 (2001) (121)
Mouse heat shock transcription factors 1 and 2 prefer a trimeric binding site but interact differently with the HSP70 heat shock element (1993) (121)
The E1A 13S product of adenovirus 5 activates transcription of the cellular human HSP70 gene (1986) (117)
Caenorhabditis elegans OSR-1 Regulates Behavioral and Physiological Responses to Hyperosmotic Environments (2004) (116)
A Genetic Screening Strategy Identifies Novel Regulators of the Proteostasis Network (2011) (115)
Mitochondrial Stress Restores the Heat Shock Response and Prevents Proteostasis Collapse during Aging. (2017) (114)
Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells. (2007) (110)
Analysis of the specificity and mechanism of transcriptional activation of the human hsp70 gene during infection by DNA viruses (1991) (107)
Effects of neurohormonal stress and aging on the activation of mammalian heat shock factor 1. (1994) (107)
Hemin-induced transcriptional activation of the HSP70 gene during erythroid maturation in K562 cells is due to a heat shock factor-mediated stress response. (1989) (106)
Proteostasis and longevity: when does aging really begin? (2014) (106)
Organization, nucleotide sequence, and transcription of the chicken HSP70 gene. (1986) (105)
The DNA-binding properties of two heat shock factors, HSF1 and HSF3, are induced in the avian erythroblast cell line HD6 (1995) (105)
Neuron-specific proteotoxicity of mutant ataxin-3 in C. elegans: rescue by the DAF-16 and HSF-1 pathways. (2011) (102)
A cellular perspective on conformational disease: the role of genetic background and proteostasis networks. (2010) (102)
Identification of a Tissue-Selective Heat Shock Response Regulatory Network (2013) (101)
Transcription of the Human HSP70 Gene: cis-Acting Elements and trans-Acting Factors Involved in Basal, Adenovirus E1A, and Stress-Induced Expression (1990) (100)
Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper (2001) (100)
Modulation of the Maladaptive Stress Response to Manage Diseases of Protein Folding (2014) (93)
Mathematical modeling of the eukaryotic heat-shock response: dynamics of the hsp70 promoter. (2005) (91)
Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation. (2007) (91)
Stress, aging, and neurodegenerative disease. (2006) (89)
Protein homeostasis as a therapeutic target for diseases of protein conformation. (2013) (89)
Modeling polyglutamine pathogenesis in C. elegans. (2006) (89)
E2F coregulates an essential HSF developmental program that is distinct from the heat-shock response (2016) (89)
In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome (2012) (87)
Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS (2017) (86)
Heat shock factor 2-like activity in mouse blastocysts. (1994) (86)
Intron-independent Association of Splicing Factors with Active Genes (1999) (85)
The loop domain of heat shock transcription factor 1 dictates DNA-binding specificity and responses to heat stress. (2001) (84)
The Chemical Biology of Molecular Chaperones--Implications for Modulation of Proteostasis. (2015) (81)
Organismal proteostasis: role of cell-nonautonomous regulation and transcellular chaperone signaling (2014) (80)
17 Regulation of Heat Shock Gene Transcription by a Family of Heat Shock Factors (1994) (80)
Detection of three protein binding sites in the serum-regulated promoter of the human gene encoding the 70-kDa heat shock protein. (1987) (79)
Activation of heat shock transcription factor 3 by c-Myb in the absence of cellular stress. (1997) (79)
Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper. (2003) (77)
Deficient induction of human hsp70 heat shock gene transcription in Y79 retinoblastoma cells despite activation of heat shock factor 1. (1994) (73)
Chromosomal location of human genes encoding major heat-shock protein HSP70 (1987) (72)
A transcriptional signature of Alzheimer’s disease is associated with a metastable subproteome at risk for aggregation (2016) (70)
14 Expression and Function of Vertebrate hsp70 Genes (1990) (70)
Nuclear colocalization of cellular and viral myc proteins with HSP70 in myc-overexpressing cells (1991) (69)
Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments (2015) (68)
Stress induction of the mammalian GRP78/BiP protein gene: in vivo genomic footprinting and identification of p70CORE from human nuclear extract as a DNA-binding component specific to the stress regulatory element (1994) (66)
Identification of cytosolic peroxisome proliferator binding protein as a member of the heat shock protein HSP70 family. (1990) (65)
Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease. (2015) (64)
Elevated CO2 levels affect development, motility, and fertility and extend life span in Caenorhabditis elegans (2009) (64)
Protein homeostasis of a metastable subproteome associated with Alzheimer’s disease (2017) (63)
The stress of misfolded proteins: C. elegans models for neurodegenerative disease and aging. (2007) (62)
A simple mass-action model for the eukaryotic heat shock response and its mathematical validation (2011) (62)
Flux of the paramyxovirus hemagglutinin-neuraminidase glycoprotein through the endoplasmic reticulum activates transcription of the GRP78-BiP gene (1991) (61)
Celastrol analogues as inducers of the heat shock response. Design and synthesis of affinity probes for the identification of protein targets. (2012) (60)
Binding of polyomavirus large T antigen to the human hsp70 promoter is not required for trans activation (1986) (60)
Disease-Modifying Pathways in Neurodegeneration (2006) (58)
Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases (2014) (57)
Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress (1993) (57)
Malfolded protein structure and proteostasis in lung diseases. (2013) (56)
The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging. (2021) (55)
Cell-Nonautonomous Regulation of Proteostasis in Aging and Disease. (2019) (54)
Heat Shock Response Activation Exacerbates Inclusion Body Formation in a Cellular Model of Huntington Disease* (2013) (53)
Cell-specific expression of heat shock proteins in chicken reticulocytes and lymphocytes (1984) (52)
Spreading of a Prion Domain from Cell-to-Cell by Vesicular Transport in Caenorhabditis elegans (2013) (51)
HSP70 mRNA translation in chicken reticulocytes is regulated at the level of elongation. (1988) (51)
Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis. (2019) (51)
How the Nucleus Copes with Proteotoxic Stress (2014) (50)
Characterizing the Altered Cellular Proteome Induced by the Stress-Independent Activation of Heat Shock Factor 1 (2014) (49)
Structure of a new crystal form of human Hsp70 ATPase domain. (1999) (49)
Transcellular chaperone signaling: an organismal strategy for integrated cell stress responses (2014) (47)
Stress and the cell nucleus: dynamics of gene expression and structural reorganization. (1999) (47)
Erythroid lineage-specific expression and inducibility of the major heat shock protein HSP70 during avian embryogenesis. (1987) (46)
Induced heat shock mRNAs escape the nucleocytoplasmic transport block in adenovirus-infected HeLa cells (1987) (46)
Remarkable stereospecific conjugate additions to the Hsp90 inhibitor celastrol. (2011) (46)
The Role of an Inverted CCAAT Element in Transcriptional Activation of the Human DNA Topoisomerase IIα Gene by Heat Shock* (1998) (45)
Caenorhabditis elegans as a model system to study intercompartmental proteostasis: Interrelation of mitochondrial function, longevity, and neurodegenerative diseases (2010) (45)
c-Myb-induced trans-activation mediated by heat shock elements without sequence-specific DNA binding of c-Myb. (1994) (44)
The Intersection of Aging Biology and the Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop. (2017) (44)
Structure-Function Analysis of the Heat Shock Factor-binding Protein Reveals a Protein Composed Solely of a Highly Conserved and Dynamic Coiled-coil Trimerization Domain* (2002) (43)
Pyrimidine-2,4,6-trione derivatives and their inhibition of mutant SOD1-dependent protein aggregation. Toward a treatment for amyotrophic lateral sclerosis. (2011) (42)
Substrate recognition and processing by a Walker B mutant of the human mitochondrial AAA+ protein CLPX. (2012) (41)
Small subclass of rat olfactory neurons with specific bulbar projections is reactive with monoclonal antibodies to the HSP70 heat shock protein (1994) (41)
In vivo properties of the disaggregase function of J‐proteins and Hsc70 in Caenorhabditis elegans stress and aging (2017) (40)
ADME-guided design and synthesis of aryloxanyl pyrazolone derivatives to block mutant superoxide dismutase 1 (SOD1) cytotoxicity and protein aggregation: potential application for the treatment of amyotrophic lateral sclerosis. (2012) (40)
Dysregulation of the proteasome increases the toxicity of ALS‐linked mutant SOD1 (2014) (39)
Proteasome Activation is a Mechanism for Pyrazolone Small Molecules Displaying Therapeutic Potential in Amyotrophic Lateral Sclerosis (2014) (38)
Odorants as cell‐type specific activators of a heat shock response in the rat olfactory mucosa (2001) (37)
Identification of compounds protective against G93A-SOD1 toxicity for the treatment of amyotrophic lateral sclerosis (2011) (36)
Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis. (2019) (35)
Erratum: Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress (Molecular and Cellular Biology 13:3 (1394-1400)) (1993) (34)
Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegans model for polyglutamine disease (2013) (34)
Macro-level Modeling of the Response of C. elegans Reproduction to Chronic Heat Stress (2012) (34)
Modification of Two Distinct COOH-terminal Domains Is Required for Murine p53 Activation by Bacterial Hsp70* (1996) (34)
Amplifiers co-translationally enhance CFTR biosynthesis via PCBP1-mediated regulation of CFTR mRNA. (2020) (34)
Restriction cleavage map of mitochonrial DNA from the yeast Saccharomyces cerevisiae. (1977) (33)
Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation Using Targeted RNA Sequencing. (2019) (33)
Restriction endonuclease analysis of mitochondrial DNA from grande and genetically characterized cytoplasmic petite clones of Saccharomyces cerevisiae. (1975) (33)
Selective activation of human heat shock gene transcription by nitrosourea antitumor drugs mediated by isocyanate-induced damage and activation of heat shock transcription factor. (1991) (32)
Neuronal Reprograming of Protein Homeostasis by Calcium-Dependent Regulation of the Heat Shock Response (2013) (32)
Tau protein aggregates inhibit the protein-folding and vesicular trafficking arms of the cellular proteostasis network (2019) (31)
Transcription and post-transcriptional regulation of avian HSP70 gene expression. (1986) (31)
Bistability explains threshold phenomena in protein aggregation both in vitro and in vivo. (2006) (30)
A method for the quantitative analysis of human heat shock gene expression using a multiplex RT-PCR assay. (1999) (30)
Fine Mapping of the Friend Retrovirus Resistance Gene, Rfv3, on Mouse Chromosome 15 (1999) (29)
cis-acting sequences and trans-acting factors required for constitutive expression of a microinjected HSP70 gene after the midblastula transition of Xenopus laevis embryogenesis. (1990) (28)
Transcription, processing, and mapping of mitochondrial RNA from grande and petite yeast. (1979) (27)
The life of proteins: the good, the mostly good and the ugly (2011) (26)
Dynamic Imaging by Fluorescence Correlation Spectroscopy Identifies Diverse Populations of Polyglutamine Oligomers Formed in Vivo* (2012) (26)
Fine structural analysis of the chicken pro alpha 2 collagen gene. (1981) (26)
Transcription factors: positive and negative regulators of cell growth and disease. (1992) (24)
Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells (1988) (23)
Restriction enzyme analysis of mitochondrial DNAs of petite mutants of yeast: Classification of petites, and deletion mapping of mitochondrial genes (1978) (23)
Challenging Proteostasis: Role of the Chaperone Network to Control Aggregation-Prone Proteins in Human Disease. (2020) (22)
Arylsulfanyl pyrazolones block mutant SOD1-G93A aggregation. Potential application for the treatment of amyotrophic lateral sclerosis. (2011) (22)
Cyclohexane 1,3-diones and their inhibition of mutant SOD1-dependent protein aggregation and toxicity in PC12 cells. (2012) (21)
Analysis of molecular chaperone activities using in vitro and in vivo approaches. (2000) (20)
Analysis of the mammalian heat-shock response. Inducible gene expression and heat-shock factor activity. (2000) (20)
Transcription and Organization of Yeast Mitochondrial DNA (1976) (19)
Regulation of Heat Shock Gene Transcription by a Family of Heat Shock Transcription Factors (1994) (18)
Embryo integrity regulates maternal proteostasis and stress resilience (2020) (18)
The DNA-Binding Properties of Two Heat Shock Factors , HSF 1 and HSF 3 , Are Induced in the Avian Erythroblast Cell Line HD 6 (1995) (17)
Mitochondrial transcription complex from Saccharomyces cerevisiae. (1981) (17)
Peptides signal mitochondrial stress. (2010) (17)
Resetting proteostasis with ISRIB promotes epithelial differentiation to attenuate pulmonary fibrosis (2021) (17)
Investigations of mechanisms of drug-induced changes in gene expression: N-methylformamide-induced changes in synthesis of the M(r) 72,000 constitutive heat shock protein during commitment of HL-60 cells to granulocyte differentiation. (1993) (16)
Stable heterogeneity of mitochondrial DNA in grande and petite strains of S. cerevisiae. (1979) (15)
Physical mapping of the yeast mitochondrial genome (1979) (15)
Chiral cyclohexane 1,3-diones as inhibitors of mutant SOD1-dependent protein aggregation for the treatment of ALS. (2012) (14)
Chemical specificity for induction of stress response genes by DNA-damaging drugs in human adenocarcinoma cells. (1988) (14)
Arylazanylpyrazolone derivatives as inhibitors of mutant superoxide dismutase 1 dependent protein aggregation for the treatment of amyotrophic lateral sclerosis. (2013) (14)
ElaTransactivation oftheHumanHSP70Promoter IsMediated through theBasal Transcriptional Complex (1989) (14)
ERdj8 governs the size of autophagosomes during the formation process (2020) (13)
HeatShock-Induced Translational Control ofHSP70andGlobin Synthesis inChicken Reticulocytes (1984) (13)
Transcriptional regulation of human hsp70 genes: relationship between cell growth, differentiation, virus infection, and the stress response. (1991) (12)
Long-range correlations and fractal dynamics in C. elegans: Changes with aging and stress. (2017) (12)
Physical mapping of genes on yeast mitochondrial DNA: Localization of antibiotic resistance loci, and rRNA and tRNA genes (1978) (12)
Erratum: Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis (Cell Metabolism (2019) 29(2) (335–347.e5), (S1550413118305862) (10.1016/j.cmet.2018.09.019)) (2019) (12)
Erratum: Widespread Proteome Remodeling and Aggregation in Aging C. elegans (Cell (2015) 161(4) (919–932) (S0092867415003207)(10.1016/j.cell.2015.03.032) (2017) (12)
A metastable subproteome underlies inclusion formation in muscle proteinopathies (2019) (11)
Physical mapping and characterization of the mitochondrial DNA and RNA sequences from mit- mutants defective in cytochrome oxidase peptide 1 (OXI 3) (1979) (11)
Physically grounded approach for estimating gene expression from microarray data (2010) (10)
Aging is associated with a systemic length-driven transcriptome imbalance (2019) (10)
The Heat Shock Transcriptional Response (1995) (10)
Aging is associated with a systemic length-associated transcriptome imbalance (2022) (9)
The Aging Microenvironment Shapes Alveolar Macrophage Identity in Aging (2019) (9)
The regulation and function of the heat shock response (2013) (9)
Tertiary Amine Pyrazolones and Their Salts as Inhibitors of Mutant Superoxide Dismutase 1-Dependent Protein Aggregation for the Treatment of Amyotrophic Lateral Sclerosis. (2015) (9)
Deuteration and fluorination of 1,3-bis(2-phenylethyl)pyrimidine-2,4,6(1H,3H,5H)-trione to improve its pharmacokinetic properties. (2014) (9)
The Heat Shock Response and the Stress of Misfolded Proteins (2010) (9)
A network approach to discerning the identities of C. elegans in a free moving population (2016) (9)
suggests a new regulatory pathway . transcription factor , heat shock factor 3 , Characterization of a novel chicken heat shock (1993) (9)
negative regulators between a family of heat shock factors, molecular chaperones, and Regulation of the heat shock transcriptional response: cross talk (2009) (8)
In vivo and in vitro Studies on the Activation and Binding of Human Heat-shock Transcription Factor (1991) (8)
Changes in HSC70 and c-myc in HL-60 [HL60] cells engaging differentiation or apoptosis (1993) (8)
Physical Mapping of Mitochondrial Genes and Transcripts in Saccharomyces cerevisiae (1977) (8)
Development and further characterization of a small subclass of rat olfactory receptor neurons that shows immunoreactivity for the HSP70 heat shock protein (1999) (8)
Physical mapping of the yeast mitochondrial genome: derivation of the fine structure and gene map of strain D273-10B and comparison with a strain (MH41-7B) differing in genome size. (1979) (8)
Protecting the future: balancing proteostasis for reproduction. (2021) (7)
Kinetic analysis reveals that independent nucleation events determine the progression of polyglutamine aggregation in C. elegans (2021) (7)
Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation using Targeted RNA-sequencing (2018) (7)
TRANSCRIPTION OF YEAST MITOCHONDRIAL DNA (1979) (7)
Protein Quality Control in Neurodegenerative Diseases (2013) (6)
5 – Protein Misfolding, Chaperone Networks, and the Heat Shock Response in the Nervous System (2007) (6)
Heat‐Shock Response (2002) (6)
ML346: A Novel Modulator of Proteostasis for Protein Conformational Diseases (2013) (5)
Ribosome-associated chaperones act as proteostasis sentinels (2013) (5)
A Comprehensive Enumeration of the Human Proteostasis Network. 1. Components of Translation, Protein Folding, and Organelle-Specific Systems (2022) (5)
Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons. (2021) (4)
The ElA 13 S Product of Adenovirus 5 Activates Transcription of the Cellular Human HSP 70 Gene (2003) (4)
Surprising features of transcriptional regulation of heat shock genes. (1991) (4)
Heat Shock Response: Cellular and Molecular Responses to Stress, Misfolded Proteins, and Diseases Associated with Protein Aggregation (2002) (4)
Proteostasis in Aging and Neurodegenerative Disease (2014) (4)
In Vivo Translation Rates Can Substantially Delay the Co-Translational Folding of the E. Coli Cytosolic Proteome (2013) (4)
Molecular Aides: The Chaperonins. (1996) (4)
Autoregulation of the Heat Shock Response (1999) (4)
Fine structural analysis of the chicken pro a2 collagen gene (4)
Stress of Life: Stress and Adaptation from Molecules to Man (1997) (4)
Inducible Transcriptional Regulation of Heat Shock Genes: Stress Signal and the Unfolded Protein Response (1998) (3)
CHAPTER 310 – The Heat-Shock Response: Sensing the Stress of Misfolded Proteins (2003) (3)
Variants in ATP6V0A1 cause progressive myoclonus epilepsy and developmental and epileptic encephalopathy (2021) (3)
Protein homeostasis : a subject collection from Cold Spring Harbor Perspectives in biology (2012) (3)
transcellular chaperone signaling Organismal proteostasis: role of cell-nonautonomous regulation and (2014) (3)
Visualizing the motion area (1993) (3)
Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity (2022) (2)
Leading Edge Commentary Geroscience : Linking Aging to Chronic Disease (2014) (2)
Investigations of Mechanisms of Drug-induced Changes in Gene Expression: W-Methylformamide-induced Changes in Synthesis of the Mr 72,000 Constitutive Heat Shock Protein during Commitment of HL-60 (1993) (2)
Proteostasis: monitoring the health of the proteome in biology, aging and disease (2013) (2)
Reply to “Far away from the lamppost” (2018) (2)
Resetting proteostasis with ISRIB prevents pulmonary fibrosis (2020) (2)
Physical mapping of the Xba I, Hinc II, Bgl II, Xho I, Sst I, and Pvu II restriction endonuclease cleavage fragments of mitochondrial DNA of S. cerevisiae (1979) (2)
Autoregulation of the Heat Shock Transcriptional Response (1998) (2)
Erratum: Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death. (Journal of Biological Chemistry (2006) 281, (9616-9622)) (2006) (2)
Proteostasis and Energetics as Proteome Hallmarks of Aging and Influenza Challenge in Pulmonary Disease (2019) (2)
Organisms The Stress of Protein Misfolding : From Single Cells to Multicellular service (2011) (2)
Analysis of mitochondrial RNA in Saccharomyces cerevisiae (1980) (2)
Protein Aggregation and Degradation (2001) (2)
encoding major heat shock protein HSP70. Structure and expression of the human gene (2012) (2)
[16] Modeling Polyglutamine Pathogenesis in C. Elegans (2006) (1)
Kinetic analysis reveals the rates and mechanisms of protein aggregation in a multicellular organism (2020) (1)
Autophagy in healthy ageing and disease (2021) (1)
Cell Stress and Proteostasis Networks in Biology, Aging, and Disease (2014) (1)
In Vitro Transcription of Drosophila Actin and Heat Shock Genes in Hela Cell-Free Extracts (1982) (1)
The Heat Shock Response: Regulation and Function of Molecular Chaperones (1997) (1)
Correction: ERdj8 governs the size of autophagosomes during the formation process (2020) (1)
The 2021 FASEB Virtual Catalyst Conference on Extracellular and Organismal Proteostasis in Health and Disease, February 3‐4, 2021 (2021) (1)
Proteome Metastability in Health, Aging, and Disease (2014) (1)
neurodegenerative disease and aging Proteotoxic stress and inducible chaperone networks in (2008) (1)
Stress in Aging and Disease The Heat Shock Response : Systems Biology of Proteotoxic (2012) (1)
Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegansmodel for polyglutamine disease (2013) (1)
Stress-Induced Expression of Heat Shock Proteins and Action of the Heat Shock Protein Effectors (2006) (1)
Biochemical events in the activation and attenuation of the heat shock transcriptional response (1998) (1)
The Heat Shock Response: Role in the Life and Death of Proteins (1998) (1)
Disease Specific Signatures Identified by RNA‐seq of Sorted Lung Cellular Populations (2017) (1)
Shock and Age (2010) (1)
Susan Lindquist 1949–2016 (2016) (1)
Correction: ERdj8 governs the size of autophagosomes during the formation process (2020) (1)
adenovirus-infected HeLa cells. nucleocytoplasmic transport block in Induced heat shock mRNAs escape the (2012) (0)
Transcription of the human hsp 7 O gene is induced by serum stimulation ( heat shock / transcriptional regulation / DNA synthesis / human cells (2003) (0)
Regulation of Functional Proteome by the Heat Shock Response and Proteostasis Network (2018) (0)
The Eukaryotic Heat Shock Transcriptional Response (1997) (0)
A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway (2023) (0)
Mitochondrial Stress Rest ores the Heat Shock Response and Prevents Proteostasis Collapse during Aging Graphical (2017) (0)
Analysis oftheSpecificity andMechanism ofTranscriptional Activation oftheHumanhsp7OGeneduring Infection byDNA Viruses (1991) (0)
reticulocytes . HSP 70 and globin synthesis in chicken Heat shock-induced translational control of (0)
A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway (2023) (0)
AMERICAN ASSOCIATION FOR CANCER RESEARCH SCIENTIFIC CONFERENCES (1995) (0)
Morimoto by constitutive phosphorylation . transcriptional activation domain is modulated Repression of the heat shock factor (1997) (0)
stability.infection on translation and mRNA shock, inhibition of protein synthesis, and expression in human cells: effects of heat Posttranscriptional regulation of hsp70 (2012) (0)
The crystal structure of the human Hsp70 ATPase domain (2004) (0)
transcription of the cellular human HSP 70 The E 1 A 13 S product of adenovirus 5 activates (2003) (0)
University of Groningen Chaperoning signaling pathways : molecular chaperones as stress-sensing ' heat shock ' proteins (2017) (0)
Table 2, Solubility at 100 μM; 1% DMSO (2013) (0)
Faculty Opinions recommendation of Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways. (2014) (0)
Polyglutamine Aggregation in a Living Animal is Governed by Biophysical Parameters (2020) (0)
reticulocytes.and globin synthesis in chicken Heat shock-induced translational control of (2012) (0)
Nuclear Colocalization ofCellular andViral myc Proteins with HSP70inmyc-Overexpressing Cells (1991) (0)
Identifi cation of compounds protective against G 93 A-SOD 1 toxicity for the treatment of amyotrophic lateral sclerosis (2010) (0)
Stress of Life: Stress and Adaptation from Molecules to Man. International Congress of Stress, an Interdisciplinary Discussion Commemorating the 90th Birth Anniversary of Hans Selye International Congress of Stress, an Interdisciplinary Discussion Commemorating the 90th Birth Anniversary of Hans Sel (1996) (0)
MaximalStress-Induced Transcription fromtheHumanHSP70 Promoter Requires Interactions withtheBasalPromoter Elements Independent ofRotational Alignment (1990) (0)
Global proteome metastability response in isogenic animals to missense mutations and polyglutamine expansions in aging (2022) (0)
C-terminal domain of protein C56C10.10, a putative peptidylprolyl isomerase, from Caenorhabditis elegans (2011) (0)
Figure 9, Stability of Probe ML346 (2013) (0)
MinireviewDynamic Remodeling of Transcription Complexes by Molecular Chaperones of the hormone receptor to its target in vivo is transient and exhibits a half-life for the glucocorticoid receptor ( GR )-DNA complex on the order of minutes ( McNally et (2002) (0)
C-terminal domain of human heat shock 70kDa protein 1B. (2010) (0)
Central domain of stress-induced protein-1 (STI-1) from C.elegans (2012) (0)
Invitro activation ofheatshocktranscription factor DNA-binding bycalcium andbiochemical conditions thataffect protein conformation (1990) (0)
Peptide-binding domain of heat shock 70 kDa protein F, mitochondrial precursor, from Caenorhabditis elegans. (2008) (0)
118. Changes in the levels of constitutively expressed but not stress-induced heat shock proteins during terminal differentiation of HL-60 human leukemia cells (1992) (0)
Figure 7, Mass spectrum, calc for M+1: 273.08, found 273.10 (2013) (0)
3P-027 Aggregation and disaggregation analysis of mutant SOD1 using fluorescence correlation spectroscopy and FLIM-FRET(The 46th Annual Meeting of the Biophysical Society of Japan) (2008) (0)
Restriction cleavage map of mitochondrial DNA from the yeast Saccharomyces cerevisiae renaturation kinetic analysisl"2 and restriction endonuclease analysis.3-5 (0)
mTOR inhibitor-independent Autophagy Activator Ameliorates Tauopathy and Prionopathy Neurodegeneration Phenotypes (2022) (0)
Polyglutamine Aggregates as a Model for Protein-misfolding Diseases (2008) (0)
Abstracts of papers presented at the 1998 Meeting on Molecular Chaperones and the Heat Shock Response, May 6-May 10, 1998 (1996) (0)
Physiological analysis of a novel ER membrane protein, ERdj8 (2017) (0)
N-terminal domain of C. elegans Hsp90 (2012) (0)
Selection ofNewHSF1andHSF2DNA-Binding Sites Reveals Differences inTrimer Cooperativity (1994) (0)
Figure 1, Probe ML346 is not toxic to HeLa cells (2013) (0)
Stress protein synthesis in cultured cardiac cells (1987) (0)
High-Content Movement Analysis as a Diagnostic Tool in \textit{C. elegans} (2013) (0)
Table 1, Hsp70 Activators PubChem Summary* (2013) (0)
Figure 3, Probe ML346 (“F1”) induces chaperone protein expression (2013) (0)
Preface/Front Matter (1990) (0)
Determining Functional Specificity of Yeast Cytosolic Hsp70 Nucleotide Exchange Factors (2011) (0)
Introduction: Special Issue on Stress-Inducible Gene Expression Conference (1999) (0)
gene.of the cellular human HSP70 The E1A 13S product of adenovirus 5 activates (2012) (0)
Abstracts of papers presented at the 1994 Meeting on Biology of Heat Shock Proteins & Molecular Chaperones, May 4-May 8, 1994 (1994) (0)
ATPase domain of human heat shock 70kDa protein 1 (1998) (0)
Figure 12, Probe ML346 (compound F1) reduces aggregation/toxicity in C. elegans models of diseases associated with polyQ expansions (2013) (0)
Figure 10, One Step Synthesis of ML346 (CID 767276) (2013) (0)
N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans (2012) (0)
On Not Judging a Book by Its Cover (1990) (0)
Coordinate Changes inHeatShockElement-Binding Activity and HSP70GeneTranscription RatesinHumanCells (1988) (0)
Protein Aggregation Inhibitors for ALS Therapy (2013) (0)
transcription rates in human cells. element-binding activity and HSP70 gene Coordinate changes in heat shock (2012) (0)
human hsp 70 gene promoter . heat shock transcription factor , interact with a CCAAT-box-binding transcription factor and Two transcriptional activators (0)
Figure 8, HPLC spectrum; purity >95% (2013) (0)
Molecular Aides: The Chaperonins . R. John Ellis, Ed. Academic Press, San Diego, 1996. xvi, 323 pp., illus., + plates. $79.95 or £59. ISBN 0-12237455- X. Cell Biology. (1996) (0)
Morimoto stability . adenovirus infection on translation and mRNA shock , inhibition of protein synthesis , and expression in human cells : effects of heat Posttranscriptional regulation of hsp 70 (2003) (0)
Multiple Regulatory Pathways of Human HSP70 Gene Transcription (1990) (0)
Figure 2, Probe ML346 (“F1”) induces Hsp70 mRNA expression (2013) (0)
A novel ER membrane protein, ERdj8 regulates the size of autophagosomes (2017) (0)
Figure 4, [a, Wild type (hsf-1+/+) and...]. (2013) (0)
A metastable subproteome underlies inclusion formation in muscle proteinopathies (2019) (0)
PNAS Plus Significance Statements (2014) (0)
Transcription ofthehumanhsp7Ogeneisinduced by serumstimulation (1985) (0)
Transcriptional regulation of human HSP70 genes (1990) (0)
heat shock protein HSP70 during avian embryogenesis. Erythroid lineage-specific expression and inducibility of the major (2011) (0)
A Multi-Omics Survey of the Age-Related Susceptibility to Influenza (2019) (0)
J-domain of dnj-12 from Caenorhabditis elegans (2007) (0)
independent of rotational alignment. interactions with the basal promoter elements the human HSP70 promoter requires Maximal stress-induced transcription from (2012) (0)
HumanHSP70promoter contains atleast twodistinct regulatory domains (1986) (0)
Peptide-binding domain of Heat shock 70 kDa protein F44E5.5 from C.elegans. (2008) (0)
Peptide-binding domain of Heat shock 70 kDa protein D precursor from C.elegans (2007) (0)
Figure 5, Probe ML346 restores proteostasis (2013) (0)
Heat Shock Gene Expression and the Analysis of Heat Shock Factor Activity (2000) (0)
Morimoto post-synaptic muscle cellsCaenorhabditis elegans Neuronal signaling modulates protein homeostasis in data (2007) (0)
Hemin-induced transcriptional activation of the HSP70 gene during erythroid maturation in K562 cells is due to a heat shock factor-mediated stress response (1989) (0)
534g) Dynamic response of c. elegans reproduction to chronic heat stress (2011) (0)
2P113 Fluorescence correlation spectroscopy detects polyglutamine small oligomers increased by knock-down of cytosolic chaperonin CCT.(31. Protein folding and misfolding (II),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006) (2006) (0)
Biallelic and de novo variants in ATP6V0A1 cause progressive myoclonus epilepsy and developmental and epileptic encephalopathy (2021) (0)
Bistability of protein aggregation as a function of molecular chaperone concentration (2005) (0)
Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues (2023) (0)
Characterization of in Vivo DNA-Protein Interactions in the Transcriptional Regulation of Human Heat Shock Genes (1997) (0)
C. elegans as a Model System to Study the Biology of Protein Aggregation and Toxicity (2010) (0)
Correction to "Chiral Cyclohexane 1,3-Diones as Inhibitors of Mutant SOD1-Dependent Protein Aggregation for the Treatment of ALS". (2017) (0)
HeatShock-Induced Interactions ofHeatShockTranscription Factor andtheHumanhsp70Promoter Examined byInVivoFootprinting (1991) (0)
Faculty Opinions recommendation of The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity. (2014) (0)
erythroleukemia cells. hemin-induced differentiation of human Activation of heat shock factor 2 during (2012) (0)
Disease-related misfolded proteins cause global perturbation in protein folding homeostasis (2009) (0)
Crystal structure of J-domain of DnaJ homolog dnj-2 precursor from C.elegans. (2007) (0)
Restoring Proteostasis via Chaperone Networks in Ageing and Neurodegenerative Disease (2009) (0)
Abstracts of papers presented at the 1991 Meeting on Stress Proteins & the Heat Shock Response, April 29-May 2, 1991 (1991) (0)
Faculty of 1000 evaluation for The hallmarks of aging. (2014) (0)
Escalating protein supersaturation underlies inclusion formation in muscle proteinopathies (2019) (0)
Chaperone molecules concentrate together with the ubiquitin-proteasome system inside particulate cytoplasmic structures : possible role in metabolism of misfolded proteins (2015) (0)
Caenorhabditis Elegans as a Model System to Study the Biology of Protein Aggregation and Toxicity (2010) (0)
Figure 11, Concentration response curve for probe ML346 (2013) (0)

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