Richard A. Murphy | Academic Influence

Richard A. Murphy's AcademicInfluence.com Rankings

Richard A. Murphy

Biology

#4257

World Rank

#6375

Historical Rank

#1621

USA Rank

Neuroscience

#901

World Rank

#937

Historical Rank

#208

USA Rank

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Biology

Richard A. Murphy's Degrees

PhD Neuroscience University of California, Berkeley
Masters Biology Stanford University

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Why Is Richard A. Murphy Influential?

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According to Wikipedia, Richard A. Murphy was an American neuroscientist. Biography Murphy was the chair of the Department of Anatomy and Cell Biology at the University of Alberta from 1986 to 1992. He then ran the Montreal Neurological Institute and Hospital at McGill University from 1992 to 2000, the Salk Institute from 2000 to 2007, and was the interim president of the California Institute for Regenerative Medicine from 2007 to 2008.

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Richard A. Murphy's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Myosin phosphorylation and the cross-bridge cycle in arterial smooth muscle. (1981) (683)
Biosynthesis and Post-translational Processing of the Precursor to Brain-derived Neurotrophic Factor* (2001) (538)
Cross-bridge phosphorylation and regulation of latch state in smooth muscle. (1988) (427)
Differential Sorting of Nerve Growth Factor and Brain-Derived Neurotrophic Factor in Hippocampal Neurons (1999) (351)
Length‐Tension Relationship of Smooth Muscle of the Hog Carotid Artery (1973) (306)
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization. (1999) (292)
Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases. (1996) (292)
Detection of brain-derived neurotrophic factor-like activity in fibroblasts and Schwann cells: Inhibition by antibodies to NGF (1991) (291)
Ca2+, crossbridge phosphorylation, and contraction. (1989) (260)
Actin and tropomyosin variants in smooth muscles. Dependence on tissue type. (1984) (254)
Expression of smooth muscle and nonmuscle myosin heavy chains in cultured vascular smooth muscle cells. (1986) (230)
Myoplasmic [Ca2+] Determines Myosin Phosphorylation in Agonist‐Stimulated Swine Arterial Smooth Muscle (1988) (206)
Myosin light chain phosphorylation associated with contraction in arterial smooth muscle. (1981) (192)
Regulation of tissue-specific expression of alternative peripheral myelin protein-22 (PMP22) gene transcripts by two promoters. (1994) (190)
Regulation of shortening velocity by cross-bridge phosphorylation in smooth muscle. (1988) (152)
What is special about smooth muscle? The significance of covalent crossbridge regulation (1994) (145)
Ca2+, cAMP, and changes in myosin phosphorylation during contraction of smooth muscle. (1983) (139)
Activation of Myosin Light Chain Phosphatase in Intact Arterial Smooth Muscle During Nitric Oxide-induced Relaxation* (2001) (137)
Two different heavy chains are found in smooth muscle myosin. (1986) (136)
Detection of Brain-derived Neurotrophic Factor in a Vesicular Fraction of Brain Synaptosomes* (1997) (134)
Sildenafil, a type-5 CGMP phosphodiesterase inhibitor, specifically amplifies endogenous cGMP-dependent relaxation in rabbit corpus cavernosum smooth muscle in vitro. (1998) (133)
Neurons Promote the Translocation of Peripheral Myelin Protein 22 into Myelin (1997) (132)
Detection and processing of peripheral myelin protein PMP22 in cultured Schwann cells. (1993) (131)
Calcium-dependent stress maintenance without myosin phosphorylation in skinned smooth muscle. (1983) (130)
Role of Ca2+ and myosin light chain phosphorylation in regulation of smooth muscle. (1982) (128)
Nitrovasodilators relax arterial smooth muscle by decreasing [Ca2+]i and uncoupling stress from myosin phosphorylation. (1992) (128)
Force-Generating Capacity and Contractile Protein Content of Arterial Smooth Muscle (1974) (128)
Neurotrophin-3 Sorts to the Constitutive Secretory Pathway of Hippocampal Neurons and Is Diverted to the Regulated Secretory Pathway by Coexpression with Brain-Derived Neurotrophic Factor (2000) (127)
The mouse submandibular gland: an exocrine organ for growth factors. (1980) (127)
Myoplasmic Calcium, Myosin Phosphorylation, and Regulation of the Crossbridge Cycle in Swine Arterial Smooth Muscle (1986) (116)
Tonic force maintenance with reduced shortening velocity in arterial smooth muscle. (1982) (113)
Transepithelial transport of epidermal growth factor by absorptive cells of suckling rat ileum. (1987) (107)
Activity-dependent activation of TrkB neurotrophin receptors in the adult CNS. (1999) (106)
Mechanical properties of the cat soleus muscle in situ. (1974) (105)
Nerve growth factor in mouse serum and saliva: role of the submandibular gland. (1977) (104)
Transforming growth factor alpha inhibits secretion of gastric acid. (1986) (86)
[Ca2+]-dependent myosin phosphorylation in phorbol diester stimulated smooth muscle contraction. (1988) (85)
Developmental changes in actin and myosin heavy chain isoform expression in smooth muscle. (1991) (84)
Secretion of nerve growth factor by central nervous system glioma cells in culture (1977) (83)
Contributions of intracellular and extracellular Ca2+ pools to activation of myosin phosphorylation and stress in swine carotid media. (1987) (83)
Two smooth muscle myosin heavy chains differ in their light meromyosin fragment. (1988) (83)
Uptake and transepithelial transport of nerve growth factor in suckling rat ileum (1986) (75)
Contractile system function in mammalian smooth muscle. (1976) (72)
Differences in cellular contractile protein contents among porcine smooth muscles: evidence for variation in the contractile system (1978) (71)
The role of myosin light chain phosphorylation in regulation of the cross-bridge cycle. (1983) (70)
Cyclic nucleotide dependent relaxation in vascular smooth muscle. (1994) (68)
The latch-bridge hypothesis of smooth muscle contraction. (2005) (68)
Force‐Velocity and Series Elastic Characteristics of Smooth Muscle from the Hog Carotid Artery (1974) (68)
Neurite development in vitro. I. The effects of adenosine 3'5'-cyclic monophosphate (cyclic AMP). (1972) (67)
Myosin phosphorylation and regulation of cross-bridge cycle in tracheal smooth muscle. (1983) (66)
Expression of nonmuscle myosin heavy and light chains in smooth muscle. (1989) (64)
Epidermal growth factor and nerve growth factor in mouse saliva: a comparative study. (1979) (63)
Special Topic: Contraction in Smooth Muscle Cells (1989) (63)
Dibutyryl Cyclic Adenosine Monophosphate Stimulation of Colcemid-Inhibited Axonal Elongation (1972) (61)
Latch-bridge model in smooth muscle: [Ca2+]i can quantitatively predict stress. (1990) (60)
Arterial actomyosin: Mg, Ca, and ATP ion dependencies for ATPase activity. (1969) (60)
Neurite development in vitro. II. The role of microfilaments and microtubules in dibutyryl adenosine 3',5'-cyclic monophosphate and nerve growth factor stimulated maturation. (1973) (60)
Muscle length, shortening, myoplasmic [Ca2+], and activation of arterial smooth muscle. (1990) (58)
Secretion of a nerve growth factor by mouse neuroblastoma cells in culture. (1975) (58)
Comparative analysis of systemic immunological parameters in ulcerative colitis and idiopathic proctitis: effects of sulfasalazine in vivo and in vitro. (1978) (57)
Cyclic AMP relaxes swine arterial smooth muscle predominantly by decreasing cell Ca2+ concentration. (1991) (57)
In vivo and in vitro effects of thymosin and adenosine deaminase on adenosine-deaminase-deficient lymphocytes. (1979) (56)
High Force Development and Crossbridge Attachment in Smooth Muscle from Swine Carotid Arteries (1982) (56)
Evidence that Brain-Derived Neurotrophic Factor from Presynaptic Nerve Terminals Regulates the Phenotype of Calbindin-Containing Neurons in the Lateral Septum (2000) (55)
Cellular and subcellular colocalization of nerve growth factor and epidermal growth factor in mouse submandibular glands (1985) (53)
Filament organization and contractile function in vertebrate smooth muscle. (1979) (51)
Selected contribution: HSP20 phosphorylation in nitroglycerin- and forskolin-induced sustained reductions in swine carotid media tone. (2001) (51)
Dependence of stress on cross-bridge phosphorylation in vascular smooth muscle. (1989) (50)
Synthesis and secretion of a high molecular weight form of nerve growth factor by skeletal muscle cells in culture. (1977) (50)
Cortisone, testosterone, and aldosterone reduce levels of nerve growth factor messenger ribonucleic acid in L-929 fibroblasts. (1987) (49)
Cooperative attachment of cross bridges predicts regulation of smooth muscle force by myosin phosphorylation. (2004) (48)
Dependence of force on length at constant cross‐bridge phosphorylation in the swine carotid media. (1995) (48)
Genistein, a tyrosine kinase inhibitor, reduces Ca2+ mobilization in swine carotid media. (1995) (47)
Myosin Phosphorylation and Cyclic Adenosine 3′,5′‐Monophosphate in Relaxation of Arterial Smooth Muscle by Vasodilators (1984) (45)
Ca2+, myosin phosphorylation, and relaxation of arterial smooth muscle. (1983) (45)
Estimates of cellular mechanics in an arterial smooth muscle. (1978) (44)
Sr2+ activates cross-bridge phosphorylation and latch state in smooth muscle. (1988) (44)
Secretagogue‐mediated discharge of nerve growth factor from granular tubules of male mouse submandibular glands: An immunocytochemical study (1978) (42)
Maximal rates of activation in electrically stimulated swine carotid media. (1987) (40)
Effects of epidermal growth factor on acid secretion from guinea pig gastric mucosa: in vitro analysis. (1985) (38)
Cross-bridge dephosphorylation and relaxation of vascular smooth muscle. (1989) (38)
The nerve growth factor receptor: a multicomponent system that mediates the actions of the neurotrophin family of proteins (1992) (37)
Inhibitory mechanisms for cross-bridge cycling: the nitric oxide-cGMP signal transduction pathway in smooth muscle relaxation. (1998) (36)
Determinants of Ca2+-dependent stress maintenance in skinned swine carotid media. (1986) (36)
Nerve growth factor: multiple dissociation products in homogenates of the mouse submandibular gland. Purification and molecular properties of the intact undissociated form of the protein. (1978) (35)
Myosin isoforms and functional diversity in vertebrate smooth muscle. (1997) (32)
Molecular properties of the nerve growth factor secreted in mouse saliva. (1977) (32)
Generation of the truncated form of the nerve growth factor receptor by rat Schwann cells. Evidence for post-translational processing. (1991) (31)
Localization of isoactins in isolated smooth muscle thin filaments by double gold immunolabeling. (1991) (30)
Myoplasmic [ Ca 2 + ] Determines Myosin Phosphorylation in Agonist-Stimulated Swine Arterial Smooth Muscle (2005) (29)
Cellular Thin Filament Protein Contents and Force Generation in Porcine Arteries andVeins (1979) (29)
Cardiac Impairment in Adrenal Insufficiency in the Cat: Reduced Adenosinetriphosphatase Activity of Myocardial Contractile Proteins (1970) (29)
Actin isoform expression, cellular heterogeneity, and contractile function in smooth muscle. (1997) (28)
Neurotrophin-4, Alone or Heterodimerized with Brain-derived Neurotrophic Factor, Is Sorted to the Constitutive Secretory Pathway* (2003) (28)
Estimates of activation in arterial smooth muscle. (1986) (28)
Energetic cost of activation processes during contraction of swine arterial smooth muscle (1997) (28)
Dependence of ATP consumption on cross‐bridge phosphorylation in swine carotid smooth muscle. (1994) (27)
Arterial actomyosin: effects of pH and temperature on solubility and ATPase activity. (1971) (26)
Contraction in smooth muscle: what is latch? (1990) (26)
The effect of priscoline, papaverine, and nicotinic acid on blood flow in the lower extremity of man. (1950) (26)
Adenosine 5'-triphosphate consumption by smooth muscle as predicted by the coupled four-state crossbridge model. (1992) (25)
Energetics of crossbridge phosphorylation and contraction in vascular smooth muscle. (1994) (25)
Absence of the α and γ subunits of 7S nerve growth factor in denervated rodent iris: Immunocytochemical studies (1986) (25)
Myosin phosphorylation and contraction of feline esophageal smooth muscle. (1985) (24)
Force-length dependence of arterial lamellar, smooth muscle, and myofilament orientations. (1987) (23)
Molecular size of nerve growth factor in dilute solution. (1976) (23)
Expression of myosin regulatory light-chain isoforms and regulation of phosphorylation in smooth muscle. (1993) (23)
cGMP mediates corpus cavernosum smooth muscle relaxation with altered cross-bridge function. (1998) (23)
Prohormone Convertases in Mouse Submandibular Gland: Co-localization of Furin and Nerve Growth Factor (1997) (23)
Dependence of stress on length, Ca2+, and myosin phosphorylation in skinned smooth muscle. (1988) (23)
Nerve growth factor and epidermal growth factor in mouse submandibular glands: identical diurnal changes and rates of secretagogue-induced synthesis. (1993) (22)
Isolation and characterization of a glycosylated form of beta nerve growth factor in mouse submandibular glands. (1989) (22)
Correlations of ATP content with mechanical properties of metabolically inhibited muscle. (1966) (22)
Ballistocardiographic patterns in intraluminal aortic obstructions. (1950) (21)
Biotyping, and epidemiological tool for coagulase-negative staphylococci. (1967) (21)
Histamine concentration and Ca2+ mobilization in arterial smooth muscle. (1989) (21)
Mechanical Properties of Carotid Arteries From DOCA Hypertensive Swine (1989) (20)
Heterologous desensitization of smooth muscle to K+ depolarization: retarded stimulus-[Ca2+]i coupling. (1997) (20)
Steady-state dependence of stress on cross-bridge phosphorylation in the swine carotid media. (1992) (19)
Myoplasmic [Ca2+] Determines Myosin Phosphorylation and Isometric Stress in Agonist‐Stimulated Swine Arterial Smooth Muscle (1988) (19)
Thyroxine reverses deficits of nerve growth factor and epidermal growth factor in submandibular glands of mice with muscular dystrophy. (1982) (19)
Biological sources of nerve growth factor. (1984) (19)
Tight binding of arterial myosin to skeletal F-actin. (1980) (19)
Changes in rat aortic actomyosin content with maturation. (1979) (19)
Chapter 26 – Regulation of Cross-bridge Cycling in Smooth Muscle (1996) (19)
Epidermal growth factor-induced precocious incisor eruption is associated with decreased tooth size. (1987) (19)
Inhibition of Ca2+-dependent contraction in swine carotid artery by myosin kinase inhibitors. (1999) (18)
Arterial actomyosin: effects of ionic strength on ATPase activity and solubility. (1971) (18)
PHOSPHORYLATION, AND CONTRACTION (1989) (18)
Immunocytochemical localization of sodium channels in an insect central nervous system using a site-directed antibody. (1993) (17)
A dilution immunoassay to measure myosin regulatory light chain phosphorylation. (2000) (16)
Dissociation of the 7S-nerve growth factor complex in solution. (1977) (16)
Submandibular glands in mice with muscular dystrophy: Studies with nerve growth factor (1981) (16)
Absence of force suppression in rabbit bladder correlates with low expression of heat shock protein 20 (2005) (16)
Hydrogen ion buffers and enzymatic activity: myosin B adenosinetriphosphatase. (1968) (15)
Contraction in smooth muscle cells. (1989) (15)
Models of the mechanism for crossbridge attachment in smooth muscle (1993) (15)
Steroids and triiodothyronine reduce nerve growth factor concentrations in medium conditioned by L-929 fibroblasts. (1986) (15)
Epidermal growth factor in the submandibular gland and serum of mice with muscular dystrophy: chemical properties in dilute gland extracts. (1979) (14)
Myosin Phosphorylation and Crossbridge Regulation in Arterial Smooth Muscle: State‐of‐the‐Art Review (1982) (14)
Myosin phosphorylation and crossbridge regulation in arterial smooth muscle. State-or-the-art review (1982) (14)
The Mouse Submandibular Gland (1980) (13)
Myosin from arterial smooth muscle: isolation following actin depolymerization. (1975) (13)
Mechanics of Vascular Smooth Muscle (2011) (12)
Improved antihyaluronidase test applicable to the microtitration technique. (1972) (12)
IN VERTEBRATE SMOOTH MUSCLE (1979) (12)
Transfer factor treatment in a patient with progressive tuberculosis. (1977) (12)
Minor role of a Ca2+-depleted sarcoplasmic reticulum in heterologous desensitization of smooth muscle to K. (1998) (11)
Suppression of Maternal Lymphocyte Mitogenic Responses by Supernatants From Short‐Term Placental Cell Cultures (1982) (10)
Absence of a Direct Effect of Phosphate or 5′‐AMP on the Contractile Proteins of Hog Carotid Arteries (1971) (10)
Production and detection of staphylococcal elastase (1977) (10)
Estimate of cellular force generation in an arterial smooth muscle with a high actin: myosin ratio. (1978) (10)
Crossbridge phosphorylation and the energetics of contraction in the swine carotid media. (1989) (9)
Stress relaxation in hog carotid artery as related to contractile activity. (1976) (9)
Ca2+-dependent regulatory mechanisms in smooth muscle. (1984) (8)
Studies on the Molecular Properties of Nerve Growth Factor and its Cellular Biosynthesis and Secretion (1976) (8)
Contractile proteins of vascular smooth muscle: effects of hydrogen and alkali metal cations on actomyosin adenosinetriphosphatase activity. (1969) (8)
Structural proteins in the myofilaments and regulation of contraction in vertebrate smooth muscle. (1976) (7)
Cholecystokinin cholecystography in the diagnosis of acalculous extrahepatic biliary tract disorders. (1978) (7)
Relationship among fibre type, myosin ATPase activity and contractile properties (1982) (7)
Covalent Cross‐bridge Regulation in Smooth Muscle a (1990) (7)
A versatile, inexpensive microstirrer for spectrophotometer cuvets. (1971) (7)
Purification and properties of staphylococcal delta-hemolysin. I. Production of delta-hemolysin. (1967) (7)
Comparison of 7S nerve growth factor and nerve growth factor I from mouse submandibular glands. (1986) (6)
Signal Transduction in Smooth Muscle Selected Contribution : HSP 20 phosphorylation in nitroglycerin-and forskolin-induced sustained reductions in swine carotid media tone (2001) (6)
Purification and Properties of Staphylococcal δ-Hemolysin I. Production of δ-Hemolysin (1967) (6)
Cross-bridge regulation by Ca(2+)-dependent phosphorylation in amphibian smooth muscle. (2001) (6)
Dependence of stress and velocity on Ca2+ and myosin phosphorylation in the skinned swine carotid media. (1987) (6)
In Vitro Activation of Smooth Muscle from the Hog Carotid Artery (1973) (5)
High affinity of various smooth muscle myosins for skeletal F-actin demonstrated by enzyme kinetics and electron microscopy. (1982) (5)
Determinants of the latch state in vascular smooth muscle. (1987) (5)
Depression of mechanical function due to active shortening in the chick anterior latissimus dorsi muscle. (1988) (5)
Large-scale production of staphylococcal delta hemolysin by the dialysis membrane technique. (1974) (4)
Control of the Actin-Myosin Interaction by Ca++ in Vascular Smooth Muscle (1978) (4)
Can different four-state crossbridge models explain latch and the energetics of vascular smooth muscle? (1991) (4)
Detection of molecules with nerve growth factor binding activity in medium conditioned by L-929 fibroblasts (1987) (4)
Crossbridge phosphorylation and regulation of vascular smooth muscle contraction. (1990) (4)
Ba2+ induces contraction in swine carotid artery by mobilizing intracellular Ca2+. (1987) (4)
Signal transduction and regulation in smooth muscle: problems and progress. (1999) (3)
Identification of staphylococcal delta-hemolysin. (1971) (3)
Partitioning of staphylococcal delta haemolysin. (1980) (3)
The release of vasoconstriction by vasodilator drugs and sympathetic nerve block; an experimental and clinical study. (1950) (3)
Contractile function defects in the soleus muscle of chronically adrenalectomized cats. (1974) (3)
Alterations in myocardial cell function in adrenal insufficiency (2004) (2)
Role of myosin isoforms in smooth muscle function. (1997) (2)
Do the cytoplasmic and muscle-specific isoforms of actin and myosin heavy and light chains serve different functions in smooth muscle? (1992) (2)
Secretion of nerve growth factor by mouse c 1300 neuroblastoma cells in vitro. Abstr. (1975) (2)
Absence of the alpha and gamma subunits of 7S nerve growth factor in denervated rodent iris: immunocytochemical studies. (1986) (1)
Potentiation of Contraction of Glycerol-Extracted Muscle by Deoxycholate (1971) (1)
Alterations in the pituitary-thyroid axis and 5'-deiodinase activity in mice with muscular dystrophy. (1985) (1)
Assessment of vascular smooth-muscle mechanisms using isolated segments of the vessel wall (2006) (1)
SECRETION OF A NGF BY MOUSE NEUROBLASTORNA CELL IN CULTURE (1975) (1)
A multiple inoculating device for bacteria. (1967) (1)
Chemomechanical Transduction in Vascular Smooth Muscle1 (1976) (1)
PURIFICATION OF STAPHYLOCOCCAL DELTA HEMOLYSIN. (1971) (1)
Kymograph: a muscle physiology toolkit (2004) (1)
The action of microapplied ATP on the contractile system of skeletal muscle fibers (1962) (1)
Control of the actin myosin interaction by calcium ion in vascular smooth muscle (1978) (0)
Synthesis and secretion of a high molecular weight form of nerve growth factor by skeletal muscle cells in culture ( conditioned culture medium / myoblasts / myotubes ) (0)
Epidermal growth factor in the submandibular glands of mice with muscular dystrophy: chemical studies. Abstr. (1978) (0)
BDNF localization in synaptotagmin-containing vesicles of PC12 cells and in synaptosomal fractions of rat brain (1996) (0)
Minor role of a Ca2+-depleted sarcoplasmic reticulum in heterologous desensitization of smooth muscle to K+. (1998) (0)
Structural analysis of submandibular gland in dystrophic mice. Abstr. (1980) (0)
Dynamic stiffness and activation in swine carotid media (1984) (0)
EXTREMITY BLOOD FLOW IN THE DOG IN THE PRESENCE OF OBSTRUCTIVE ARTERIAL CLOTS (1951) (0)
Arterial Smooth Muscle Contraction Is Dependent on Sustained Increases in Myoplasmic Ca2 (1989) (0)
Crossbridges and contraction in smooth muscle (1992) (0)
Letters to the Editor Phosphorylation of Hsp20 on Serine 157 (2001) (0)
Detection of prohormone convertases in developing and adult mouse submandibular glands (1994) (0)
Improved Antihyaluronidas e TestApplicable (1972) (0)
Possible nonspecific immunopotentiation by 2,4-dinitrochlorobenzene sensitization in patients with Hodgkin's disease. (1979) (0)
Hydrogen Ion Buffers and Enzymatic Activity : Myosin (2003) (0)
Ca2+, crossbridge phosphorylation and the latch state in smooth muscle (1992) (0)

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