Richard Perham
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English molecular biologist
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Why Is Richard Perham Influential?
(Suggest an Edit or Addition)According to Wikipedia, Richard Nelson Perham, FRS, FMedSci, FRSA , was Professor of biochemistry at the University of Cambridge, and Master of St John's College, Cambridge 2004–07. He was also editor-in-chief of FEBS Journal from 1998 to 2013.
Richard Perham's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Redesign of the coenzyme specificity of a dehydrogenase by protein engineering (1990) (668)
- Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactions. (2000) (532)
- Domains, motifs, and linkers in 2-oxo acid dehydrogenase multienzyme complexes: a paradigm in the design of a multifunctional protein. (1991) (386)
- Glyceraldehyde 3-phosphate dehydrogenases: I. The protein chains in glyceraldehyde 3-phosphate dehydrogenase from pig muscle (1965) (371)
- Reversible blocking of amino groups with citraconic anhydride. (1968) (327)
- Pulling geometry defines the mechanical resistance of a β-sheet protein (2003) (318)
- A common structural motif in thiamin pyrophosphate‐binding enzymes (1989) (311)
- Multiple display of foreign peptides on a filamentous bacteriophage. Peptides from Plasmodium falciparum circumsporozoite protein as antigens. (1991) (287)
- Purification of 2-oxo acid dehydrogenase multienzyme complexes from ox heart by a new method. (1980) (176)
- Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes. (1999) (164)
- A Molecular Switch and Proton Wire Synchronize the Active Sites in Thiamine Enzymes (2004) (152)
- Glutathione reductase from Escherichia coli: cloning and sequence analysis of the gene and relationship to other flavoprotein disulfide oxidoreductases. (1986) (147)
- Role of capsid structure and membrane protein processing in determining the size and copy number of peptides displayed on the major coat protein of filamentous bacteriophage. (1996) (140)
- Immunological properties of foreign peptides in multiple display on a filamentous bacteriophage. (1993) (135)
- The mechanical behaviour of frozen earth materials under high pressure triaxial test conditions (1972) (119)
- Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase. (1996) (119)
- Three-dimensional structure of the lipoyl domain from Bacillus stearothermophilus pyruvate dehydrogenase multienzyme complex. (1993) (117)
- Identification, molecular cloning and sequence analysis of a gene cluster encoding the Class II fructose 1,6‐bisphosphate aldolase, 3‐phosphoglycerate kinase and a putative second glyceraldehyde 3‐phosphate dehydrogenase of Escherichia coli (1989) (110)
- Pulling geometry defines the mechanical resistance of a beta-sheet protein. (2003) (104)
- Phage display of peptide epitopes from HIV-1 elicits strong cytolytic responses (2000) (100)
- Three-dimensional solution structure of the E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli. (1994) (100)
- Creation of an NADP-dependent pyruvate dehydrogenase multienzyme complex by protein engineering. (1993) (97)
- Genetic reconstruction and functional analysis of the repeating lipoyl domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1985) (96)
- Self-assembly and catalytic activity of the pyruvate dehydrogenase multienzyme complex of Escherichia coli (1977) (96)
- The reaction of aldolase with 2-methylmaleic anhydride. (1970) (94)
- DNA sequence of the filamentous bacteriophage Pf1. (1991) (93)
- Purification and characterization of two fructose diphosphate aldolases from Escherichia coli (Crookes' strain). (1973) (91)
- Self-assembly of biological macromolecules. (1975) (89)
- Prediction of the three‐dimensional structures of the biotinylated domain from yeast pyruvate carboxylase and of the lipoylated H‐protein from the pea leaf glycine cleavage system: A new automated method for the prediction of protein tertiary structure (1993) (88)
- The high-resolution structure of the peripheral subunit-binding domain of dihydrolipoamide acetyltransferase from the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. (1994) (88)
- Inhibition of pyruvate dehydrogenase multienzyme complex from Escherichia coli with mono- and bifunctional arsenoxides. (1978) (88)
- Crystal structure of the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex. (2007) (87)
- Molecular weight and symmetry of the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1979) (84)
- Kinetics and specificity of reductive acylation of lipoyl domains from 2-oxo acid dehydrogenase multienzyme complexes. (1989) (80)
- Selective inactivation of the transacylase components of the 2-oxo acid dehydrogenase multienzyme complexes of Escherichia coli. (1976) (76)
- Three-dimensional structure of the major autoantigen in primary biliary cirrhosis. (1998) (76)
- Structural mimicry and enhanced immunogenicity of peptide epitopes displayed on filamentous bacteriophage. The V3 loop of HIV-1 gp120. (1994) (76)
- Structural dependence of post-translational modification and reductive acetylation of the lipoyl domain of the pyruvate dehydrogenase multienzyme complex. (1994) (75)
- Conformational flexibility and folding of synthetic peptides representing an interdomain segment of polypeptide chain in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1989) (75)
- The pyruvate dehydrogenase multienzyme complex (1992) (74)
- Structure and selectivity in post‐translational modification: attaching the biotinyl–lysine and lipoyl–lysine swinging arms in multifunctional enzymes (1999) (73)
- Solution structures of apo and holo biotinyl domains from acetyl coenzyme A carboxylase of Escherichia coli determined by triple-resonance nuclear magnetic resonance spectroscopy. (1999) (72)
- Dual role of a single multienzyme complex in the oxidative decarboxylation of pyruvate and branched-chain 2-oxo acids in Bacillus subtilis. (1983) (71)
- Interactions between DNA and coat protein in the structure and assembly of filamentous bacteriophage fd (1987) (70)
- Molecular Structure of a 9-MDa Icosahedral Pyruvate Dehydrogenase Subcomplex Containing the E2 and E3 Enzymes Using Cryoelectron Microscopy* (2006) (69)
- Mobility of polypeptide chain in the pyruvate dehydrogenase complex revealed by proton NMR (1981) (69)
- Structure and symmetry of B. stearothermophilus pyruvate dehydrogenase multienzyme complex and implications for eucaryote evolution (1979) (66)
- Multiple display of peptides and proteins on a macromolecular scaffold derived from a multienzyme complex. (2001) (66)
- Processing of filamentous bacteriophage virions in antigen-presenting cells targets both HLA class I and class II peptide loading compartments. (2003) (66)
- The molecular origins of specificity in the assembly of a multienzyme complex. (2005) (65)
- Three-dimensional structure of the lipoyl domain from the dihydrolipoyl succinyltransferase component of the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli. (1996) (64)
- Repeating functional domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1984) (63)
- Switching kinetic mechanism and putative proton donor by directed mutagenesis of glutathione reductase. (1989) (62)
- Use of dimethyl suberimidate and novel periodate-cleavable bis(imido esters) to study the quaternary structure of the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1976) (62)
- Rapid intramolecular coupling of active sites in the pyruvate dehydrogenase complex of Escherichia coli: mechanism for rate enhancement in a multimeric structure. (1978) (60)
- Polarity of the RNA in the tobacco mosaic virus particle and the direction of protein stripping in sodium dodecyl sulphate (1976) (59)
- Chain folding in the dihydrolipoyl acyltransferase components of the 2‐oxo‐acid dehydrogenase complexes from Escherichia coli (1986) (59)
- Interaction of the globular domains of pIII protein of filamentous bacteriophage fd with the F-pilus of Escherichia coli. (1999) (59)
- AMINO ACID SEQUENCES AROUND THE REACTIVE CYSTEINE RESIDUES IN GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES. (1963) (58)
- Restricted motion of the lipoyl-lysine swinging arm in the pyruvate dehydrogenase complex of Escherichia coli. (2000) (57)
- Reductive and oxidative half-reactions of glutathione reductase from Escherichia coli. (1994) (57)
- Autoantibodies in primary biliary cirrhosis: Analysis of reactivity against eukaryotic and prokaryotic 2‐oxo acid dehydrogenase complexes (1991) (56)
- Structure of the periplasmic domain of Pseudomonas aeruginosa TolA: evidence for an evolutionary relationship with the TonB transporter protein (2002) (56)
- The polarity of stripping of coat protein subunits from the RNA in tobacco mosaic virus under alkaline conditions (1976) (56)
- Anatomy of an engineered NAD‐binding site (1994) (55)
- Studies of an acid-induced species of purple membrane from Halobacterium halobium. (1978) (55)
- Flavin fluorescence dynamics and photoinduced electron transfer in Escherichia coli glutathione reductase. (1998) (55)
- NMR structure of the principal neutralizing determinant of HIV-1 displayed in filamentous bacteriophage coat protein. (1997) (55)
- Three-dimensional structure of a lipoyl domain fromthe dihydrolipoyl acetyltransferase component of the pyruvate dehydrogenase multienzyme complex of Escherichia coli (1995) (55)
- Delineating the site of interaction on the pIII protein of filamentous bacteriophage fd with the F-pilus of Escherichia coli. (2002) (54)
- Pf1 filamentous bacterial virus. X-ray fibre diffraction analysis of two heavy-atom derivatives. (1981) (53)
- Segmental structure and protein domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. Genetic reconstruction in vitro and 1H-n.m.r. spectroscopy. (1987) (53)
- Evidence for two lipoic acid residues per lipoate acetyltransferase chain in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1976) (53)
- The subunit molecular weights of the α‐ketoacid dehydrogenase multienzyme complexes from E. coli (1971) (53)
- Cloning, sequence analysis and over-expression of the gene for the class II fructose 1,6-bisphosphate aldolase of Escherichia coli. (1989) (52)
- Methods for obtaining peptide maps of proteins on a subnanomole scale. (1975) (52)
- Amino acid sequence analysis of the lipoyl and peripheral subunit-binding domains in the lipoate acetyltransferase component of the pyruvate dehydrogenase complex from Bacillus stearothermophilus. (1988) (51)
- 2-Oxo acid dehydrogenase multi-enzyme complexes: in the beginning and halfway there. (1987) (51)
- The characterization of intermediates formed during the disassembly of tobacco mosaic virus at alkaline pH. (1978) (51)
- Selectivity of post-translational modification in biotinylated proteins: the carboxy carrier protein of the acetyl-CoA carboxylase of Escherichia coli. (1998) (49)
- Purification and characterization of glutathione reductase encoded by a cloned and over-expressed gene in Escherichia coli. (1987) (49)
- Domain structure and 1H-n.m.r. spectroscopy of the pyruvate dehydrogenase complex of Bacillus stearothermophilus. (1984) (49)
- Expression of genes encoding the E2 and E3 components of the Bacillus stearothermophilus pyruvate dehydrogenase complex and the stoichiometry of subunit interaction in assembly in vitro. (1998) (49)
- Chemical modification of the coat protein in bacteriophage fd and orientation of the virion during assembly and disassembly. (1983) (48)
- Cloning and sequence analysis of the genes encoding the dihydrolipoamide acetyltransferase and dihydrolipoamide dehydrogenase components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. (1990) (48)
- Structure of the capsid of Pf3 filamentous phage determined from X-ray fibre diffraction data at 3.1 A resolution. (1998) (48)
- Structure of the NADPH-binding motif of glutathione reductase: efficiency determined by evolution. (1994) (48)
- A comparative study of the structure of muscle fructose 1,6-diphosphate aldolases. (1969) (46)
- Purificaton of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus and resolution of its four component polypeptides. (1980) (46)
- Recognition of HIV-derived B and T cell epitopes displayed on filamentous phages. (1999) (45)
- Investigation of the mechanism of active site coupling in the pyruvate dehydrogenase multienzyme complex of Escherichia coli by protein engineering. (1988) (44)
- Cooperativity induced by a single mutation at the subunit interface of a dimeric enzyme: glutathione reductase. (1992) (44)
- Engineering the substrate specificity of glutathione reductase toward that of trypanothione reduction. (1991) (44)
- Engineering a peptide epitope display system on filamentous bacteriophage. (1995) (43)
- Instrumentation in amino acid sequence analysis (1975) (43)
- Conformational studies of the interdomain linker peptides in the dihydrolipoyl acetyltransferase component of the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1992) (43)
- A highly sensitive method for amino-acid analysis by a double-isotope-labelling technique using dansyl chloride. (1973) (43)
- Limited proteolysis and sequence analysis of the 2-oxo acid dehydrogenase complexes from Escherichia coli. Cleavage sites and domains in the dihydrolipoamide acyltransferase components. (1987) (43)
- The reactivity of thiol groups and the subunit structure of aldolase. (1970) (43)
- Alternative proton donors/acceptors in the catalytic mechanism of the glutathione reductase of Escherichia coli: the role of histidine-439 and tyrosine-99. (1989) (42)
- Expression in Escherichia coli of genes encoding the E1 alpha and E1 beta subunits of the pyruvate dehydrogenase complex of Bacillus stearothermophilus and assembly of a functional E1 component (alpha 2 beta 2) in vitro. (1994) (42)
- Thermodynamic analysis of the binding of component enzymes in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus (2002) (42)
- Recognition of a surface loop of the lipoyl domain underlies substrate channelling in the pyruvate dehydrogenase multienzyme complex. (1996) (42)
- The protein capsid of filamentous bacteriophage PH75 from Thermus thermophilus. (2001) (41)
- Substrate channelling in 2-oxo acid dehydrogenase multienzyme complexes. (2001) (40)
- Limited proteolysis of the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1979) (40)
- Self-assembly and catalytic activity of the pyruvate dehydrogenase multienzyme complex from Bacillus stearothermophilus. (1999) (40)
- The stoichiometry of polypeptide chains in the pyruvate dehydrogenase multienzyme complex of E. Coli determined by a simple novel method (1975) (38)
- The comparative structure of mammalian glyceraldehyde 3-phosphate dehydrogenases. (1969) (38)
- Novel kinetic and structural properties of the class-I D-fructose 1,6-bisphosphate aldolase from Escherichia coli (Crookes' strain). (1978) (38)
- Detection of anti-p53 antibodies by ELISA using p53 synthetic or phage-displayed peptides. (2002) (37)
- Simultaneous display of different peptides on the surface of filamentous bacteriophage. (1997) (36)
- Expression in Escherichia coli of a sub‐gene encoding the lipoyl domain of the pyruvate dehydrogenase complex of Bacillus stearothermophilus (1990) (36)
- Interaction of component enzymes with the peripheral subunit-binding domain of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus: stoichiometry and specificity in self-assembly. (1995) (36)
- Reactivity and structural role of protein amino groups in tobacco mosaic virus. (1968) (36)
- Regulation of filamentous bacteriophage length by modification of electrostatic interactions between coat protein and DNA. (1991) (35)
- Reaction of tobacco mosaic virus with a thiol-containing imidoester and a possible application to X-ray diffraction analysis. (1971) (35)
- Purification and characterization of the class-II D-fructose 1,6-bisphosphate aldolase from Escherichia coli (Crookes' strain). (1978) (34)
- Factors limiting display of foreign peptides on the major coat protein of filamentous bacteriophage capsids and a potential role for leader peptidase (1998) (34)
- Intramolecular coupling of active sites in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1978) (33)
- Site-directed mutagenesis and 1H NMR spectroscopy of an interdomain segment in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1988) (33)
- Bromopyruvate as an active-site-directed inhibitor of the pyruvate dehydrogenase multienzyme complex from Escherichia coli. (1984) (33)
- Structure of a putative lipoate protein ligase from Thermoplasma acidophilum and the mechanism of target selection for post-translational modification. (2006) (33)
- New vectors for peptide display on the surface of filamentous bacteriophage. (1996) (32)
- The reversible reaction of protein amino groups with exo-cis-3,6-endoxo-Δ4-tetrahydrophthalic anhydride. The reaction with lysozyme (1970) (32)
- Matching electrostatic charge between DNA and coat protein in filamentous bacteriophage. Fibre diffraction of charge-deletion mutants. (1995) (32)
- Spin-label study of the mobility of enzyme-bound lipoic acid in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1976) (32)
- Sucrose density-gradient analysis of the alkaline degradation of tobacco mosaic virus. (1969) (32)
- Competitive interaction of component enzymes with the peripheral subunit-binding domain of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus: kinetic analysis using surface plasmon resonance detection. (1996) (31)
- Stereoisomers of tetrahydrothiamin pyrophosphate, potent inhibitors of the pyruvate dehydrogenase multienzyme complex from Escherichia coli. (1983) (31)
- Isolation and mapping of glutathione reductase-negative mutants of Escherichia coli K12. (1982) (30)
- Altering kinetic mechanism and enzyme stability by mutagenesis of the dimer interface of glutathione reductase. (1995) (30)
- Kinetic analysis of the role of lipoic acid residues in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1980) (30)
- Sequence-specific 1H-NMR assignments and secondary structure of the lipoyl domain of the Bacillus stearothermophilus pyruvate dehydrogenase multienzyme complex. (1991) (30)
- Limited proteolysis and proton NMR spectroscopy of Bacillus stearothermophilus pyruvate dehydrogenase multienzyme complex. (1982) (30)
- Induction of specific T-helper and cytolytic responses to epitopes displayed on a virus-like protein scaffold derived from the pyruvate dehydrogenase multienzyme complex. (2003) (29)
- New enzymes for old: Redesigning the coenzyme and substrate specificities of glutathione reductase (1991) (29)
- Identification and specificity of pilus adsorption proteins of filamentous bacteriophages infecting Pseudomonas aeruginosa. (2006) (29)
- The fructose-1,6-bisphosphate aldolases: same reaction, different enzymes. (1990) (29)
- Use of fusion proteins and procaryotic display systems for delivery of HIV-1 antigens: development of novel vaccines for HIV-1 infection. (2003) (29)
- Structural differences between wild-type NADP-dependent glutathione reductase from Escherichia coli and a redesigned NAD-dependent mutant. (1993) (28)
- The determination of the order of lysine-containing tryptic peptides of proteins by diagonal paper electrophoresis. A carboxyl-terminal sequence for pepsin. (1967) (28)
- Two lipoyl domains in the dihydrolipoamide acetyltransferase chain of the pyruvate dehydrogenase multienzyme complex of Streptococcus faecalis (1991) (28)
- The peripheral subunit-binding domain of the dihydrolipoyl acetyltransferase component of the pyruvate dehydrogenase complex of Bacillus stearothermophilus: preparation and characterization of its binding to the dihydrolipoyl dehydrogenase component. (1994) (28)
- Lipoic acid residues in a take-over mechanism for the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1981) (28)
- Reaction mechanism of the heterotetrameric (alpha2beta2) E1 component of 2-oxo acid dehydrogenase multienzyme complexes. (2003) (27)
- Molecular Biology of Assemblies and Machines (2016) (26)
- Wild-type and mutant forms of the pyruvate dehydrogenase multienzyme complex from Bacillus subtilis. (1983) (26)
- Amino acid sequence homology in the active site of rabbit and sturgeon muscle aldolases (1970) (25)
- Reconstitution of the pyruvate dehydrogenase multienzyme complex from Bacillus stearothermophilus. (1982) (25)
- Limited proteolysis and proton n.m.r. spectroscopy of the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli. (1981) (25)
- Structural determinants of post-translational modification and catalytic specificity for the lipoyl domains of the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (2000) (25)
- An amino acid sequence in the active site of lipoamide dehydrogenase from pig heart. (1974) (25)
- Identification of key amino acid residues in the assembly of enzymes into the pyruvate dehydrogenase complex of Bacillus stearothermophilus: a kinetic and thermodynamic analysis. (2002) (25)
- Effects of temperature and Y21M mutation on conformational heterogeneity of the major coat protein (pVIII) of filamentous bacteriophage fd. (1999) (25)
- Variable electrostatic interaction between DNA and coat protein in filamentous bacteriophage assembly. (1988) (25)
- Distinct modes of recognition of the lipoyl domain as substrate by the E1 and E3 components of the pyruvate dehydrogenase multienzyme complex. (2007) (24)
- Pulling geometry defines the mechanical resistance of a β-sheet protein (2003) (24)
- Extended polypeptide linkers establish the spatial architecture of a pyruvate dehydrogenase multienzyme complex. (2008) (23)
- Polypeptide-chain stoicheiometry and lipoic acid content of the pyruvate dehydrogenase complex of Escherichia coli. (1979) (23)
- Reaction of tobacco mosaic virus with maleic anhydride and some possible applications to x-ray diffraction analysis. (1971) (23)
- Effects of modification of the tyrosine residues of bacteriorhodopsin with tetranitromethane. (1979) (23)
- Reductive acetylation of tandemly repeated lipoyl domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli is random order. (1989) (22)
- Site‐directed mutagenesis of a loop at the active site of E1 (α2β2) of the pyruvate dehydrogenase complex (2003) (22)
- Recognition of the lipoyl domain is the ultimate determinant of substrate channelling in the pyruvate dehydrogenase multienzyme complex. (2001) (22)
- Swinging arms in multifunctional enzymes and the specificity of post-translational modification. (1998) (21)
- Quaternary structure of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus studied by a new reversible cross-linking procedure with bis(imidoesters). (1982) (20)
- Evidence for Tilted Smectic Liquid Crystalline Packing of fd Inovirus from X-ray Fiber Diffraction (1996) (19)
- Isolation and nucleotide sequence of a cDNA encoding human calmodulin. (1984) (19)
- The DNA‐binding protein of Pf1 filamentous bacteriophage: amino‐acid sequence and structure of the gene (1982) (19)
- Protein-protein interaction revealed by NMR T(2) relaxation experiments: the lipoyl domain and E1 component of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. (2000) (19)
- The pyruvate dehydrogenase multi-enzyme complex of Escherichia coli: genetic reconstruction and functional analysis of the lipoyl domains (1986) (19)
- An extended amino acid sequence around the reactive cysteine residues of glyceraldehyde 3-phosphate dehydrogenase. (1966) (18)
- Three-dimensional structure of a lipoyl domain from the dihydrolipoyl acetyltransferase component of the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1995) (18)
- A diagonal paper-electrophoretic technique for studying amino acid sequences around the cysteine and cystine residues of proteins. (1967) (18)
- Sites of limited proteolysis in the pyruvate decarboxylase component of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus and their role in catalysis. (2000) (18)
- The lipoamide dehydrogenase component of the 2-oxo acid dehydrogenase multienzyme complexes of Escherichia coli. (1978) (18)
- Analysis of X-ray diffraction from fibres of Pf1 Inovirus (filamentous bacteriophage) shows that the DNA in the virion is not highly ordered. (1998) (18)
- Interactions of the peripheral subunit-binding domain of the dihydrolipoyl acetyltransferase component in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. (2003) (17)
- The role of loop and beta-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex. (2008) (17)
- Interactions of lipoyl domains with the E1p subunits of the pyruvate dehydrogenase multienzyme complex from Escherichia coli (1990) (16)
- Intermediates in the disassembly of tobacco mosaic virus at alkaline pH Infectivity, self-assembly, and translational activities. (1978) (16)
- Amino-terminal sequences of two mouse lambda chains. (1968) (16)
- Temperature-dependence of intramolecular coupling of active sites in pyruvate dehydrogenase multienzyme complexes. (1983) (16)
- Expression in Escherichia coli of a sub-gene encoding the lipoyl and peripheral subunit-binding domains of the dihydrolipoamide acetyltransferase component of the pyruvate dehydrogenase complex of Bacillus stearothermophilus. (1992) (16)
- A mutant pyruvate dehydrogenase complex of Escherichia coli deleted in the (alanine + proline)-rich region of the acetyltransferase component. (1987) (15)
- Kinetic and molecular properties of citraconyl-aldolase. The reversible denaturation and hybridization of the native and modified enzymes. (1974) (15)
- Intramolecular coupling of active sites in the pyruvate dehydrogenase multienzyme complexes from bacterial and mammalian sources. (1981) (15)
- The reaction of protein amino groups with methyl 5-iodopyridine-2-carboximidate. A possible general method of preparing isomorphous heavy-atom derivatives of proteins. (1973) (15)
- Lambda Bence Jones proteins of the mouse: chemical and immunological characterization. (1967) (15)
- Thioredoxin. 3. Amino acid sequences of the peptic peptides from S-aminoethylated peptide B. (1968) (14)
- Preparation of an isomorphous heavy-atom derivative of tobacco mosaic virus by chemical modification with 4-sulpho-phenylisothiocyanate. (1974) (14)
- Amino acid sequence around lipoic acid residues in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1980) (14)
- The reactivity of functional groups as a probe for investigating the topography of tobacco mosaic virus. The use of mutants with additional lysine residues in the coat protein. (1973) (14)
- Lipoylation of the E2 components of the 2-oxo acid dehydrogenase multienzyme complexes of Escherichia coli. (1991) (14)
- Engineering surface charge. 2. A method for purifying heterodimers of Escherichia coli glutathione reductase. (1992) (13)
- Nuclear-magnetic-resonance spectroscopy studies of the flexible linkages between lipoyl domains in the pyruvate dehydrogenase multienzyme complex from Escherichia coli (1986) (13)
- Interaction of protein domains in the assembly and mechanism of 2-oxo acid dehydrogenase multienzyme complexes (1996) (13)
- Conformational mobility of polypeptide chains in the 2‐oxo acid dehydrogenase complexes from ox heart revealed by proton NMR spectroscopy (1981) (13)
- Modification of the coat protein charge and its effect on the stability of the U1 strain of tobacco mosaic virus at alkaline pH. (1985) (12)
- The role of lipoic acid residues in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. (1981) (12)
- Folding domains and intramolecular ionic interactions of lysine residues in glyceraldehyde 3-phosphate dehydrogenase. (1977) (12)
- A surface loop directs conformational switching of a lipoyl domain between a folded and a novel misfolded structure. (2009) (12)
- Extended amino acid sequences around the active-site lysine residue of class-I fructose 1,6-bisphosphate aldolases from rabbit muscle, sturgeon muscle, trout muscle and ox liver. (1979) (12)
- Interaction of avidin with the lipoyl domains in the pyruvate dehydrogenase multienzyme complex : three-dimensional location and similarity to biotinyl domains in carboxylases (1992) (12)
- Amino acid sequence homology between muscle and liver aldolases (1971) (11)
- Flavins and flavoproteins 2002 (2002) (11)
- Isolation and properties of the branched-chain 2-keto acid and pyruvate dehydrogenase multienzyme complex from Bacillus subtilis. (1988) (11)
- Solubilizing buried domains of proteins: a self-assembling interface domain from glutathione reductase. (1994) (10)
- Accessibility of Peptides Displayed on Filamentous Bacteriophage Virions: Susceptibllity to Proteinases (1997) (10)
- A designed mutant of the enzyme glutathione reductase shortens the crystallization time by a factor of forty. (1994) (10)
- Cross-linking and 1H n.m.r. spectroscopy of the pyruvate dehydrogenase complex of Escherichia coli. (1982) (10)
- Site-directed mutagenesis of a loop at the active site of E1 (alpha2beta2) of the pyruvate dehydrogenase complex. A possible common sequence motif. (2003) (10)
- Glutathione reductase from Escherichia coli: mutation, cloning and sequence analysis of the gene. (1987) (10)
- The Structure of Immunoglobulin Light Chains (1967) (10)
- A synthesis of acylphosphonic acids and of 1-aminoalkylphosphonic acids: the action of pyruvate dehydrogenase and lactate dehydrogenase on acetylphosphonic acid. (1991) (8)
- Dual importance of positive charge in the C-terminal region of filamentous bacteriophage coat protein for membrane insertion and DNA-protein interaction in virus assembly. (1989) (8)
- Intramolecular ionic interactions of lysine residues and a possible folding domain in fructose diphosphate aldolase. (1977) (8)
- Solution structure of the lipoyl domain of the chimeric dihydrolipoyl dehydrogenase P64K from Neisseria meningitidis. (2001) (8)
- A Molecular Switch and Proton-Wire Synchronize the Active Sites in Thiamine-Dependent Enzymes (2004) (8)
- Amidination of pyruvate dehydrogenase complex of Escherichia coli under denaturing conditions. (1979) (8)
- DIHYDROLIPOAMIDE DEHYDROGENASE COMPLEXED WITH THE BINDING DOMAIN OF THE DIHYDROLIPOAMIDE ACETYLASE (1996) (7)
- CHAPTER 8 – Multiple Display of Foreign Peptide Epitopes on Filamentous Bacteriophage Virions (1996) (7)
- Introducing the FEBS Journal for 2005 (2004) (6)
- Prediction of the binding site on E1 in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus (2003) (6)
- Protein engineering of domains in flavoprotein disulphide oxidoreductases: contributions to folding and assembly. (1996) (6)
- Effect of coat protein mutations in bacteriophage fd studied by sedimentation analysis. (1992) (6)
- Structure and posttranslational modification of lipoyl domain of 2-oxo-acid dehydrogenase multienzyme complexes. (1995) (6)
- Engineering surface charge. 1. A method for detecting subunit exchange in Escherichia coli glutathione reductase. (1992) (6)
- A comparison of the glyceraldehyde 3‐phosphate dehydrogenase from ox muscle and liver (1974) (5)
- Phage display of epitopes from HIV-1 elicits strong cytolytic responses in vitro and in vivo. (2001) (5)
- Rapid removal of acetimidoyl groups from proteins and peptides. Applications to primary structure determination. (1981) (5)
- Cloning and expression of the filamentous bacteriophage Pf1 major coat protein gene in Escherichia coli. Membrane protein processing and virus assembly. (1987) (4)
- Protein-protein recognition mediated by a mini-protein domain: possible evolutionary significance. (1994) (4)
- Structural aspects of biomolecular recognition and self-assembly. (1994) (4)
- SHORT COMMUNICATION Isolation and Mapping of Glutathione Reductase-negative Mutants of Escherichia coli K 12 (1982) (4)
- FEBS Journal and online‐only publishing (2013) (4)
- Cloning and sequence analysis of the genes encoding the alpha and beta subunits of the E1 component of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. (1990) (4)
- Structural investigations of peptides and proteins (1976) (4)
- Limited proteolysis of the pyruvate dehydrogenase multienzyme complex of Bacillus subtilis. (1985) (4)
- Amino-acid sequence homology in the muscle aldolases from sturgeons of different species. (1972) (4)
- Enzymes, 1. General (2008) (3)
- Flavoprotein disulphide oxidoreductases: protein engineering of glutathione reductase from Escherichia coli. (1988) (3)
- The Domain Structures of the E2 Components of the Pyruvate Dehydrogenase Multienzyme Complexes from Bacillus stearothermophilus and Saccharomyces cerevisiae (1989) (3)
- Mobility and active-site coupling in 2-oxo acid dehydrogenase complexes. (1983) (3)
- MPSA short communications (1988) (3)
- Synthesis of methyl[3H]acetimidate of high specific radioactivity, a reagent for radiolabeling proteins. (1980) (3)
- Comparison of aldolases extracted from rabbit muscle at low and high ionic strength. (1970) (3)
- Expression of human calmodulin cDNA in Escherichia coli and characterization of the protein. (1988) (2)
- Phage-display of antigenic peptides applied to vaccine design. (1998) (2)
- Substrate channelling in the pyruvate dehydrogenase multienzyme complex (2002) (2)
- SOLUTION STRUCTURE OF HOLO-BIOTINYL DOMAIN FROM ACETYL COENZYME A CARBOXYLASE OF ESCHERICHIA COLI DETERMINED BY TRIPLE-RESONANCE NMR SPECTROSCOPY (1999) (2)
- The Protein chemistry of enzymes (1976) (2)
- Electron-spin-resonance studies of the lipoamide 'swinging arm' of the pyruvate dehydrogenase multienzyme complex of Escherichia coli [proceedings]. (1978) (2)
- Enzyme biochemistry (1978) (2)
- INNER CORE AND DOMAIN-STRUCTURE OF THE PYRUVATE-DEHYDROGENASE MULTI-ENZYME COMPLEX OF BACILLUS-STEAROTHERMOPHILUS (1980) (1)
- Protein technologies and commercial enzymes (2000) (1)
- MULTIFUNCTIONAL ENZYME COMPLEXES: MULTISTEP CATALYSIS BY MOLECULAR MACHINES (2004) (1)
- Discussion: The mechanical behaviour of frozen earth materials under high pressure triaxial test conditions (1973) (1)
- The oxidative and reductive half reactions of subunit interface mutants of Escherichia coli glutathione reductase. (1996) (1)
- Protein structure: New approaches to disease and therapy: by Max Perutz, W. H. Freeman, 1992. £33.95 (hbk) £22.95 (pbk) (326 pages) ISBN 0 7167 7021 0 (hbk) 0 7167 7022 9 (pbk) (1993) (1)
- Exploration of the coenzyme and substrate specificity of glutathione reductase and its subunit assembly (1990) (1)
- Flavins and flavoproteins 2002 : proceedings of the Fourteenth International Symposium, St.John's College, University of Cambridge, UK, July 14 - 18, 2002 (2002) (1)
- Structure and Function of Icosahedral Pyruvate Dehydrogenase Complexes (2006) (1)
- Chemists' enzymes (1985) (1)
- The lipoyl domain and its role in thiamin diphosphate-dependent oxidative decarboxylation. (1992) (1)
- DNA-protein interactions and DNA packaging in filamentous bacteriophages (1986) (1)
- Pentaerythritol tetranitrate reductase: reaction with NADPH, steroids, 2-cyclohexenone, nitroesters and nitroaromatic explosives (2002) (0)
- SITE-DIRECTED MUTAGENESIS AND TIIE MECHANISM OF FLAVOPROTEIN DISULPHIDE OXIDOREDUCfASES (1989) (0)
- Coffee-table enzymology (1991) (0)
- Structure of protein Ta0514, putative lipoate protein ligase from T. acidophilum. (2005) (0)
- Deletions in a surface loop divert the folding of a protein domain into a metastable dimeric form (2009) (0)
- Genetically engineered bacteriophage and vaccines containing them. (1991) (0)
- FoldingDomains and htramolecular Ionic Interactions ofLysine Residues in Glyceraldehyde 3-Phosphate Dehydrogenase (2005) (0)
- Multifunctional Enzyme Complexes as Catalytic Nanomachines: Architecture as a Contributor to Catalysis (2005) (0)
- The Structure and Post-Translational Modification of Lipoyl Domains in 2-Oxo Acid Dehydrogenase Multienzyme Complexes (1991) (0)
- Cloning and sequence analysis of the genes for glycolytic enzymes from Escherichia coli (1986) (0)
- Site-directed mutagenesis and the mechanism of flavoprotein disulphide oxidoreductases (1989) (0)
- Prizes awarded by FEBS Journal and FEBS Letters from 2015 (2013) (0)
- An investigation of engineered cooperativity in mutants of Escherichia coli glutathione reductase (1993) (0)
- Crystallographic studies on the icosahedral core of the pyruvate dehydrogenase multienzyme complex fromBacillus stearothermophilus (1996) (0)
- LIPOYL DOMAIN FROM THE DIHYDROLIPOYL SUCCINYLTRANSFERASE COMPONENT OF THE 2-OXOGLUTARATE DEHYDROGENASE MULTIENZYME COMPLEX OF ESCHERICHIA COLI, NMR, 25 STRUCTURES (1998) (0)
- Molecular Structure of an Icosahedral Pyruvate Dehydrogenase Complex (2002) (0)
- Review of the needs for European synchrotron and related beam-lines for biological and biomedical research (1998) (0)
- The dihydrolipoyl acyltransferase components of the 2-oxo acid dehydrogenase complexes from Escherichia coli: identification of a region of polypeptide chain involved in binding the E3 subunit (1986) (0)
- Glutathione reductase: mutation, cloning and sequence analysis of the gene in E. coli (1984) (0)
- Nuclear-magnetic-resonance spectroscopy studies of the flexible linkages between lipoyl domains in the pyruvate dehydrogenase multienzyme complex from Eschevichiu coli (2009) (0)
- DNA-Protein Interactions and Protein-Protein Interactions in Filamentous Bacteriophage Assembly (1995) (0)
- Segmental structure andprotein domains inthepyruvate dehydrogenase multienzyme complex ofEscherichia coli Genetic reconstruction invitro and1H-n.m.r. spectroscopy (1987) (0)
- INNERMOST LIPOYL DOMAIN OF THE PYRUVATE DEHYDROGENASE FROM ESCHERICHIA COLI (1999) (0)
- PP3D-22 (Poster): Crystal structure of the cell wall anchor domain of MotB, the stator component of the bacterial flagellar motor: Implications for peptidoglycan recognition (2008) (0)
- Hybrid molecules of glutathione reductase: tools for investigating protein interactions at the dimer interface (1994) (0)
- Editorial Board (1985) (0)
- Pseudomonas aeruginosa TolA Domain III, Seleno-methionine Derivative (2002) (0)
- The subunit molecular weights of the alpha-ketoacid dehydrogenase multienzyme complexes from E. coli. (1971) (0)
- INNER LIPOYL DOMAIN FROM HUMAN PYRUVATE DEHYDROGENASE (PDH) COMPLEX, NMR, 1 STRUCTURE (1997) (0)
- A POSSIBLE GENERAL METHOD OF PREPARING ISOMORPHOUS HEAVY-ATOM DERIVATIVES OF PROTEINS By MALCOLM RILEY* and RICHARD N. PERHAM (2005) (0)
- Active site coupling in multienzyme complexes (2005) (0)
- The crystal structure of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain of E2 (2004) (0)
- Enzymology: the general and the specific (1982) (0)
- Protein engineering of glutathione reductase: over-expression of the gene from Escherichia coli (1986) (0)
- INOVIRUS (FILAMENTOUS BACTERIOPHAGE) STRAIN PF3 MAJOR COAT PROTEIN ASSEMBLY (1998) (0)
- Structure-Function Relationships of Proteins: Proceedings of the Third John Innes Symposium Edited by R. Markham and R. W. Home Elsevier/North-Holland; Amsterdam, New York, 1976 viii + 204 pages. (1979) (0)
- Structural investigation of peptides and proteins Part I: Primary structure and chemical modification (1969) (0)
- New crystal form of the Pseudomonas putida branched-chain dehydrogenase (E1) (2005) (0)
- Editorial Board (2004) (0)
- Structural investigation of peptides and proteins (1970) (0)
- Structure of protein Ta0514, putative lipoate protein ligase from T. acidophilum with bound lipoic acid (2005) (0)
- Editorial Board (2003) (0)
- Time-resolved flavin fluorescence quenching. (1997) (0)
- Chemical Probes of Topography and Subunit Interactions in a Simple Dehydrogenase and a Multienzyme Complex (1977) (0)
- Rotational diffusion of the eosin-labelled lipoyl residues of bacterial pyruvate dehydrogenase complexes (1986) (0)
- Bacteriophage filamenteux double-hybride recombinant (2000) (0)
- The reactivity of thiol groups in aldolase. (1970) (0)
- E. COLI 2-oxoglutarate dehydrogenase (E1o) (2007) (0)
- Protein engineering of glutathione reductase from Escherichia coli. (1987) (0)
- The nucleohistones Edited by James Bonner and Paul Ts'o. Pp. xvii + 398. Holden-Day Inc., San Francisco, London, and Amsterdam. 1964. $12.75 (1965) (0)
- The reversible reaction of protein amino groups with exo-cis-3,6-endoxo-delta-tetrahydrophthalic anhydride. (1970) (0)
- Molecular structures of icosahedral pyruvate dehydrogenase complexes from B stearothermophilus determined by cryo electron microscopy (2004) (0)
- Dynamic Participation of Protein Domains in Catalysis by 2-Oxo Acid Dehydrogenase Multienzyme Complexes (1988) (0)
- Subunit interactions in the glutathione reductase from Escherichia coli (1990) (0)
- Introduction to protein structure: edited by Carl Branden and John Tooze, Garland Publishing, 1991. $49.95 (xv + 302 pages) ISBN 0 8153 0344 0 (1992) (0)
- Structure and electronic properties of inovirus (1991) (0)
- Malcolm Dixon, 18 April 1899 - 7 December 1985 (1988) (0)
- PROCEEDINGS OF THE BIOCHEMICAL SOCIETY. (2018) (0)
- A central role for extended polypeptide linkers in establishing the spatial architecture of a pyruvate dehydrogenase complex (2007) (0)
- Active site mutants of the glutathione reductase from Escherichia coli (1990) (0)
- Filamentous Bacteriophage PH75 (2001) (0)
- Structure and Post-Translational Modification of the Lipoyl Domain of 2-Oxo Acid Dehydrogenase Complexes: A New Family of Protein Domains (1993) (0)
- Fifty years of muscle contraction (2004) (0)
- The thiol groups of aldolase. (1970) (0)
- Prizes awarded by FEBS Letters and FEBS Journal from 2015 (2013) (0)
- Gentknologisk modified bacteriophage and vaccines containing such (1991) (0)
- Recipes for success in the laboratory (1985) (0)
- DIHYDROLIPOYL TRANSACETYLASE (E.C.2.3.1.12) CATALYTIC DOMAIN (RESIDUES 184-425) FROM BACILLUS STEAROTHERMOPHILUS (1999) (0)
- Structure of the Capsid of Pf3 inovirus Determined from 3.1 Fibre Diffraction Data (1997) (0)
- NMR structure of the peripheral-subunit binding domain of Bacillus stearothermophilus E2p (2004) (0)
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