Richard Scheller
Neuroscientist
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Biology
Richard Scheller's Degrees
- PhD Chemistry California Institute of Technology
- Bachelors Chemistry University of California, Santa Cruz
Why Is Richard Scheller Influential?
(Suggest an Edit or Addition)According to Wikipedia, Richard H. Scheller is the former Chief Science Officer and Head of Therapeutics at 23andMe and the former Executive Vice President of Research and Early Development at Genentech. He was a professor at Stanford University from 1982 to 2001 before joining Genentech. He has been awarded the Alan T. Waterman Award in 1989, the W. Alden Spencer Award in 1993 and the NAS Award in Molecular Biology in 1997, won the 2010 Kavli Prize in Neuroscience with Thomas C. Südhof and James E. Rothman, and won the 2013 Albert Lasker Award for Basic Medical Research with Thomas Südhof. He was also given the Life Sciences Distinguished Alumni Award from University of Wisconsin–Madison. He is a Fellow of the American Academy of Arts and Sciences and a Member of the National Academy of Sciences.
Richard Scheller's Published Works
Published Works
- SNAREs — engines for membrane fusion (2006) (2405)
- A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion (1993) (1872)
- A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis (2007) (1308)
- Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. (1992) (1271)
- SNARE-mediated membrane fusion (2001) (1155)
- Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index (2008) (1034)
- Defective Neuromuscular Synaptogenesis in Agrin-Deficient Mutant Mice (1996) (906)
- Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates (2012) (789)
- Three-dimensional structure of the neuronal-Sec1–syntaxin 1a complex (2000) (748)
- A genomic perspective on membrane compartment organization (2001) (696)
- The syntaxin family of vesicular transport receptors (1993) (651)
- Specificity and regulation of a synaptic vesicle docking complex (1994) (596)
- The molecular machinery for secretion is conserved from yeast to neurons. (1993) (579)
- Sec6/8 Complex Is Recruited to Cell–Cell Contacts and Specifies Transport Vesicle Delivery to the Basal-Lateral Membrane in Epithelial Cells (1998) (556)
- VAMP-1: a synaptic vesicle-associated integral membrane protein. (1988) (548)
- Mechanisms of synaptic vesicle exocytosis. (2000) (519)
- Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin. (2004) (469)
- SNARE Complex Formation Is Triggered by Ca2+ and Drives Membrane Fusion (1999) (420)
- n-Sec1: a neural-specific syntaxin-binding protein. (1994) (402)
- Protein-protein interactions contributing to the specificity of intracellular vesicular trafficking. (1994) (390)
- Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A). (1999) (387)
- A role for dystrophin-associated glycoproteins and utrophin in agrin-induced AChR clustering (1994) (383)
- Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome (2011) (377)
- Structural Organization of the Synaptic Exocytosis Core Complex (1997) (370)
- Subunit Composition, Protein Interactions, and Structures of the Mammalian Brain sec6/8 Complex and Septin Filaments (1998) (359)
- Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins (2004) (345)
- Synaptic vesicle biogenesis, docking, and fusion: a molecular description. (1996) (343)
- The rat brain synucleins; family of proteins transiently associated with neuronal membrane. (1991) (330)
- SNAREs and NSF in targeted membrane fusion. (1997) (313)
- The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans (1993) (309)
- Structure and expression of a rat agrin (1991) (309)
- Tomosyn: a Syntaxin-1–Binding Protein that Forms a Novel Complex in the Neurotransmitter Release Process (1998) (305)
- Two vesicle-associated membrane protein genes are differentially expressed in the rat central nervous system. (1989) (298)
- Syntaxin 6 functions in trans-Golgi network vesicle trafficking. (1997) (289)
- A single gene encodes multiple neuropeptides mediating a stereotyped behavior (1983) (287)
- Syntaxin 13 Mediates Cycling of Plasma Membrane Proteins via Tubulovesicular Recycling Endosomes (1998) (281)
- Nsec1 Binds a Closed Conformation of Syntaxin1a (2000) (276)
- Phosphorylation of Munc-18/n-Sec1/rbSec1 by Protein Kinase C (1996) (274)
- The Mammalian Brain rsec6/8 Complex (1996) (267)
- Botulinum Neurotoxin Type C Cleaves a Single Lys-Ala Bond within the Carboxyl-terminal Region of Syntaxins (*) (1995) (265)
- Seven Novel Mammalian SNARE Proteins Localize to Distinct Membrane Compartments* (1998) (265)
- SNARE Interactions Are Not Selective (1999) (262)
- Nitric Oxide Modulates Synaptic Vesicle Docking/Fusion Reactions (1996) (256)
- A molecular description of synaptic vesicle membrane trafficking. (1994) (245)
- A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes. (2000) (242)
- Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer (2010) (242)
- Vesicle-associated membrane protein and synaptophysin are associated on the synaptic vesicle. (1994) (233)
- Three SNARE complexes cooperate to mediate membrane fusion (2001) (219)
- SV2, a brain synaptic vesicle protein homologous to bacterial transporters. (1992) (219)
- Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugates. (2005) (218)
- Protein Interactions Regulating Vesicle Transport between the Endoplasmic Reticulum and Golgi Apparatus in Mammalian Cells (1997) (217)
- Three Novel Proteins of the Syntaxin/SNAP-25 Family* (1998) (214)
- A role for synaptotagmin (p65) in regulated exocytosis (1993) (213)
- Mutations in the Exocyst Component Sec5 Disrupt Neuronal Membrane Traffic, but Neurotransmitter Release Persists (2003) (213)
- RNA splicing regulates agrin-mediated acetylcholine receptor clustering activity on cultured myotubes (1992) (210)
- Distinct domains of syntaxin are required for synaptic vesicle fusion complex formation and dissociation (1995) (206)
- The sec6/8 Complex Is Located at Neurite Outgrowth and Axonal Synapse-Assembly Domains (1999) (205)
- SNAREs Contribute to the Specificity of Membrane Fusion (2000) (203)
- Vamp-7 Mediates Vesicular Transport from Endosomes to Lysosomes (1999) (201)
- Synaptic vesicle membrane proteins interact to form a multimeric complex (1992) (201)
- Identification of synaptic proteins and their isoform mRNAs in compartments of pancreatic endocrine cells. (1994) (197)
- Isolation and characterization of a drosophila neuropeptide gene (1988) (193)
- Subunit structure of the mammalian exocyst complex. (1997) (191)
- Developmental regulation of highly active alternatively spliced forms of agrin (1993) (190)
- Peri-Golgi vesicles contain retrograde but not anterograde proteins consistent with the cisternal progression model of intra-Golgi transport (2001) (187)
- The Biochemistry of Neurotransmitter Secretion(*) (1995) (187)
- Aplysia neurons express a gene encoding multiple FMRFamide neuropeptides (1985) (185)
- Rab14 is involved in membrane trafficking between the Golgi complex and endosomes. (2004) (184)
- Cellular and molecular biology of neuropeptide processing and packaging (1989) (183)
- Phosphorylation of synaptic vesicle proteins: modulation of the alpha SNAP interaction with the core complex. (1996) (183)
- Brain contains two forms of synaptic vesicle protein 2. (1993) (174)
- Targeting vesicles to specific sites on the plasma membrane: the role of the sec6/8 complex. (1999) (174)
- Multiple neuropeptides derived from a common precursor are differentially packaged and transported (1988) (173)
- Down syndrome critical region protein 1 (DSCR1), a novel VEGF target gene that regulates expression of inflammatory markers on activated endothelial cells. (2004) (172)
- Localization, Dynamics, and Protein Interactions Reveal Distinct Roles for ER and Golgi SNAREs (1998) (169)
- In situ hybridization to study the origin and fate of identified neurons. (1983) (167)
- Regulation of Membrane Trafficking Structural Insights from a Rab/Effector Complex (1999) (161)
- Cellular and molecular biology of the presynaptic nerve terminal. (1991) (157)
- Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs. (2008) (154)
- Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking. (1999) (149)
- Dale's hypothesis revisited: different neuropeptides derived from a common prohormone are targeted to different processes. (1990) (148)
- A family of genes that codes for ELH, a neuropeptide eliciting a stereotyped pattern of behavior in Aplysia (1982) (146)
- Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking. (1999) (145)
- Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase (2005) (145)
- VAMP/synaptobrevin isoforms 1 and 2 are widely and differentially expressed in nonneuronal tissues (1996) (138)
- A New Syntaxin Family Member Implicated in Targeting of Intracellular Transport Vesicles* (1996) (135)
- Quantitative measurement of mast cell degranulation using a novel flow cytometric annexin-V binding assay. (1999) (134)
- The Cysteine String Secretory Vesicle Protein Activates Hsc70 ATPase* (1996) (134)
- Sequential SNARE Assembly Underlies Priming and Triggering of Exocytosis (2001) (132)
- Fluorescence detection in capillary zone electrophoresis using a charge-coupled device with time-delayed integration. (1991) (125)
- Hrs-2 is an ATPase implicated in calcium-regulated secretion (1997) (124)
- Use of 2,3-naphthalenedicarboxaldehyde derivatization for single-cell analysis of glutathione by capillary electrophoresis and histochemical localization by fluorescence microscopy. (1995) (121)
- Agrin mediates cell contact-induced acetylcholine receptor clustering (1991) (119)
- Structure and chromosomal localization of the mammalian agrin gene (1992) (119)
- Identification of a Novel Rab11/25 Binding Domain Present in Eferin and Rip Proteins* (2001) (118)
- Sorting within the regulated secretory pathway occurs in the trans- Golgi network (1990) (118)
- Dynamics of Tubulovesicular Recycling Endosomes in Hippocampal Neurons (1999) (117)
- Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex (2003) (116)
- Syntaxin 18, a SNAP Receptor That Functions in the Endoplasmic Reticulum, Intermediate Compartment, and cis-Golgi Vesicle Trafficking* (2000) (114)
- The Sec6/8 complex in mammalian cells: Characterization of mammalian Sec3, subunit interactions, and expression of subunits in polarized cells (2001) (114)
- Differential expression of the p65 gene family (1991) (110)
- Cysteine string protein, a DnaJ family member, is present on diverse secretory vesicles (1995) (107)
- Death-receptor activation halts clathrin-dependent endocytosis (2006) (107)
- Molecular Characterization of Rab11 Interactions with Members of the Family of Rab11-interacting Proteins* (2004) (107)
- Peptidergic modulation of neuronal circuitry controlling feeding in Aplysia (1987) (105)
- Biochemical and immunocytological localization of molluscan small cardioactive peptides in the nervous system of Aplysia californica (1985) (105)
- A fusion of new ideas (1997) (104)
- Prohormone processing and the secretory pathway. (1988) (99)
- Sharing Publication-Related Data and Materials: Responsibilities of Authorship in the Life Sciences1 (2003) (98)
- The RCP-Rab11 complex regulates endocytic protein sorting. (2004) (97)
- A Novel SNARE N-terminal Domain Revealed by the Crystal Structure of Sec22b* (2001) (95)
- p65 fragments, homologous to the C2 region of protein kinase C, bind to the intracellular receptors for protein kinase C. (1992) (93)
- Calmodulin and Protein Kinase C Increase Ca2+-stimulated Secretion by Modulating Membrane-attached Exocytic Machinery* (1999) (93)
- Cysteine string protein (CSP) is an insulin secretory granule‐associated protein regulating β‐cell exocytosis (1998) (93)
- Calcium Can Disrupt the SNARE Protein Complex on Sea Urchin Egg Secretory Vesicles without Irreversibly Blocking Fusion* (1998) (92)
- The small cardioactive peptides A and B of Aplysia are derived from a common precursor molecule. (1985) (90)
- Specific representation of cloned repetitive DNA sequences in sea urchin RNAs (1978) (90)
- The Di-leucine Motif of Vesicle-associated Membrane Protein 4 Is Required for Its Localization and AP-1 Binding* (2001) (88)
- Mammalian Vesicle Trafficking Proteins of the Endoplasmic Reticulum and Golgi Apparatus (*) (1996) (87)
- SNARE proteins mediate lipid bilayer fusion. (1999) (86)
- Amisyn, a Novel Syntaxin-binding Protein That May Regulate SNARE Complex Assembly* (2002) (85)
- Membrane trafficking in the presynaptic nerve terminal. (1995) (84)
- Syntaxin Modulation of Slow Inactivation of N-Type Calcium Channels (2000) (83)
- Phosphorylated Syntaxin 1 Is Localized to Discrete Domains Along a Subset of Axons (2000) (83)
- Neuropeptides: mediators of behavior in Aplysia. (1984) (81)
- Alternative RNA splicing that determines agrin activity regulates binding to heparin and alpha-dystroglycan. (1996) (80)
- Site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity through linker and antibody engineering. (2014) (80)
- Two rat homologs of clathrin-associated adaptor proteins. (1994) (78)
- rab15, a novel low molecular weight GTP-binding protein specifically expressed in rat brain. (1992) (77)
- Probing single secretory vesicles with capillary electrophoresis. (1998) (76)
- Rab37 is a novel mast cell specific GTPase localized to secretory granules (2000) (76)
- Ceramide 1‐Phosphate Phosphatase Activity in Brain (1993) (76)
- Syntaxin 17 is abundant in steroidogenic cells and implicated in smooth endoplasmic reticulum membrane dynamics. (2000) (75)
- Organization and expression of multiple actin genes in the sea urchin (1981) (73)
- SNARE Membrane Trafficking Dynamics In Vivo (1999) (72)
- Localization of Aplysia neurosecretory peptides to multiple populations of dense core vesicles (1986) (72)
- Syntaxin 11 is an atypical SNARE abundant in the immune system. (2000) (72)
- Tomosyn Binds t-SNARE Proteins via a VAMP-like Coiled Coil (1998) (70)
- rSec6 and rSec8, mammalian homologs of yeast proteins essential for secretion. (1995) (70)
- Self-association of the H3 Region of Syntaxin 1A (2001) (69)
- Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene (2007) (66)
- Recordings from Single Neocortical Nerve Terminals Reveal a Nonselective Cation Channel Activated by Decreases in Extracellular Calcium (2004) (66)
- Syntaxin-6 SNARE involvement in secretory and endocytic pathways of cultured pancreatic beta-cells. (2004) (64)
- A family of ras-like GTP-binding proteins expressed in electromotor neurons. (1991) (64)
- Gene isolation with cDNA probes from identified aplysia neurons: Neuropeptide modulators of cardiovascular physiology (1983) (63)
- Repetitive sequence transcripts in the mature sea urchin oocyte (1978) (63)
- Generation and Maintenance of Neuronal Polarity Mechanisms of Transport and Targeting (1999) (62)
- VAT 1: An abundant membrane protein from torpedo cholinergic synaptic vesicles (1989) (61)
- The ionic layer is required for efficient dissociation of the SNARE complex by α-SNAP and NSF (2001) (60)
- Structure and expression of the egg-laying hormone gene family in Aplysia (1985) (59)
- Agrin inhibits neurite outgrowth but promotes attachment of embryonic motor and sensory neurons. (1997) (58)
- Characteristics of individual repetitive sequence families in the sea urchin genome studied with cloned repeats (1978) (58)
- A single gene encodes multiple peptide-transmitter candidates involved in a stereotyped behavior (1983) (58)
- Organization and expression of the Drosophila FMRFamide-related prohormone gene. (1990) (58)
- Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog (2002) (56)
- Differential expression of transcripts from syb, a Drosophila melanogaster gene encoding VAMP (synaptobrevin) that is abundant in non-neuronal cells. (1993) (56)
- SNARE Protein Trafficking in Polarized MDCK Cells (2000) (55)
- Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking. (1996) (55)
- Membrane fusion: SNARE the rod, coil the complex (1998) (53)
- Molecular biology of synaptic vesicle-associated proteins (1988) (52)
- Crystal Structure and Biophysical Properties of a Complex between the N-terminal SNARE Region of SNAP25 and Syntaxin 1a* (2001) (52)
- Egg-laying hormone genes of Aplysia: evolution of the ELH gene family (1986) (51)
- Synaptic vesicle proteins and regulated exocytosis. (1993) (50)
- Association of three small GTP‐binding proteins with cholinergic synaptic vesicles (1993) (49)
- The function and differential sorting of a family of aplysia prohormone processing enzymes (1994) (49)
- Evolutionary change in the repetition frequency of sea urchin DNA sequences (1978) (49)
- Repetitive sequences of the sea urchin genome. III. Nucleotide sequences of cloned repeat elements. (1981) (49)
- Processing of the egg-laying hormone (ELH) precursor in the bag cell neurons of Aplysia. (1988) (49)
- Single cells as biosensors for chemical separations. (1995) (48)
- Agrin-induced clustering of acetylcholine receptors: a cytoskeletal link (1994) (47)
- Repetitive sequences of the sea urchin genome. Distribution of members of specific repetitive families. (1981) (47)
- Mechanisms of vesicle docking and fusion: insights from the nervous system. (1994) (47)
- Proteolytic processing of the Aplysia egg-laying hormone and R3-14 neuropeptide precursors (1987) (47)
- Better Late Than Never: A Role for Rabs Late in Exocytosis (1997) (45)
- Calcium Regulation of Exocytosis in PC12 Cells* (2001) (45)
- Clones of individual repetitive sequences from sea urchin DNA constructed with synthetic Eco RI sites. (1977) (45)
- Spontaneous injection in microcolumn separations. (1994) (44)
- Torpedo synaptophysin: evolution of a synaptic vesicle protein (1990) (43)
- An alpha-helical minimal binding domain within the H3 domain of syntaxin is required for SNAP-25 binding. (1997) (42)
- Patch-Clamp Detection of Neurotransmitters in Capillary Electrophoresis (1996) (41)
- Molecular correlates of synaptic vesicle docking and fusion (1994) (41)
- How genes control an innate behavior. (1984) (41)
- A neuropeptide precursor expressed in Aplysia neuron L5. (1986) (40)
- Neuropeptides in identified Aplysia neurons. (1985) (38)
- Cell biology: The specifics of membrane fusion (2000) (37)
- Antibodies to synthetic peptides defined by cDNA cloning reveal a network of peptidergic neurons in Aplysia (1984) (36)
- The Core Membrane Fusion Complex Governs the Probability of Synaptic Vesicle Fusion But Not Transmitter Release Kinetics (2002) (35)
- A rab protein regulates the localization of secretory granules in AtT-20 cells. (1993) (34)
- Rac and Rab GTPases dual effector Nischarin regulates vesicle maturation to facilitate survival of intracellular bacteria (2013) (34)
- A Discontinuous SNAP-25 C-terminal Coil Supports Exocytosis* (2001) (34)
- Egg-laying hormone of Aplysia induces a voltage-dependent slow inward current carried by Na+ in an identified motoneuron. (1986) (33)
- Protein transport. A fusion of new ideas. (1997) (32)
- Cell biology: Lipid membranes shape up (1999) (32)
- Expression of mutant ELH prohormones in AtT-20 cells: the relationship between prohormone processing and sorting (1993) (32)
- Separation and characterization of amines from individual atrial gland vesicles of Aplysia californica. (1998) (30)
- SNAP-25 Ser187 does not mediate phorbol ester enhancement of hippocampal synaptic transmission (2003) (29)
- Physiological Modulation of Rabphilin Phosphorylation (2001) (29)
- Histidine-rich basic peptide: a cardioactive neuropeptide from Aplysia neurons R3-14. (1987) (27)
- Repetitive sequences of the sea urchin genome. II. Subfamily structure and evolutionary conservation. (1981) (26)
- IMPLICATIONS FOR INTERMEDIATES IN SNARE COMPLEX ASSEMBLY (2001) (25)
- Regulated release of multiple peptides from the bag cell neurons ofAplysia californica (1990) (25)
- nSec 1 Binds a Closed Conformation of Syntaxin 1 A (2000) (25)
- Expression of the L11 neuropeptide gene in the Aplysia central nervous system (1985) (24)
- An improved and robust DNA immunization method to develop antibodies against extra-cellular loops of multi-transmembrane proteins (2014) (24)
- Identification of a novel alternatively spliced septin (1999) (24)
- The ionic layer is required for efficient dissociation of the SNARE complex by alpha-SNAP and NSF. (2001) (22)
- Microcolumn sample injection by spontaneous fluid displacement. (1994) (22)
- rab15, a novel low molecular weight GTP-binding protein specifically expressed in rat brain. (1992) (22)
- Neuropeptides in identified Aplysia neurons: precursor structure, biosynthesis and physiological actions (1987) (21)
- Agrin: a synaptic basal lamina protein that regulates development of the neuromuscular junction. (1992) (21)
- Biosynthesis and sorting of neuropeptides (1991) (21)
- Characterization of a cDNA encoding a subunit of the rat brain rsec6/8 complex. (1997) (20)
- Fusion Without SNAREs? (2001) (20)
- Expression of the egg-laying hormone gene family in the head ganglia ofAplysia (1986) (20)
- Identification of receptor ligands and receptor subtypes using antagonists in a capillary electrophoresis single-cell biosensor separation system. (1995) (19)
- An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody–Drug Conjugate for the Treatment of Hormone Receptor–Positive Breast Cancer (2017) (19)
- A synaptic vesicle specific GTP-binding protein from ray electric organ. (1991) (17)
- Cellular and synaptic morphology of a feeding motor circuit in Aplysia californica (1987) (17)
- Cell-to-cell scanning in capillary electrophoresis. (1996) (17)
- A dense core vesicle protein is restricted to the cortex of granules in the exocrine atrial gland of Aplysia california. (1989) (17)
- Secretion in AtT-20 cells stably transfected with soluble synaptotagmins. (1994) (17)
- Aplysia californica neurons express microinjected neuropeptide genes (1987) (16)
- A Unique Neurofilament from Torpedo Electric Lobe: Sequence, Expression, and Localization Analysis (1990) (15)
- Synaptic vesicle proteins and regulated exocytosis (1993) (15)
- Crystal Structure and Biophysical Properties of a Complex Between the N-terminal SNARE Region of SNAP 25 and Syntaxin 1 a (2001) (15)
- Agrin and the organization of the neuromuscular junction (1992) (14)
- In search of the molecular mechanism of intracellular membrane fusion and neurotransmitter release (2013) (14)
- Developmental Regulation and Specific Brain Distribution of Phosphorabphilin (2001) (13)
- The molecular basis of a neuroendocrine fixed action pattern: egg laying in Aplysia. (1983) (12)
- Subcellular Fractionation of Prohormone Processing Products in the Bag Cell Neurons (1990) (12)
- Proteolytic processing of a peptide precursor in Aplysia neuron R14. (1986) (11)
- Synapse formation: a molecular perspective (1998) (11)
- Inhibition of agrin‐mediated acetylcholine receptor clustering by utrophin C‐terminal peptides (1996) (9)
- Optimizing fluorescence detection in chemical separations for analyte bands traveling at different velocities. (1993) (9)
- Isolation and characterization of two homologous cDNA clones from Torpedo electromotor neurons. (1989) (9)
- Ablation of P y Q-type Ca 2 1 channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the a 1A -subunit (1999) (8)
- Insight into the molecular mechanisms of synaptic vesicle docking and fusion. (1995) (7)
- MOLECULAR BIOLOGY AND PHYSIOLOGY OF APLYSIA NEUROPEPTIDES (1988) (7)
- Large dense cored vesicles are enriched in neuropeptide processing intermediates in the Aplysia bag cells. (1989) (7)
- A mammalian homologue of SLY1, a yeast gene required for transport from endoplasmic reticulum to Golgi. (1996) (7)
- Neurohormones in Invertebrates: Evolution of peptide hormones: an Aplysia CRF-like peptide (1988) (7)
- Molecular mechanisms of synaptic vesicle docking and membrane fusion (1994) (7)
- Low molecular weight proteins of Aplysia neurosecretory cells (1985) (7)
- Proteolytic processing of theAplysia A peptide precursor in AtT-20 cells (1994) (7)
- Synaptic vesicle proteins and exocytosis. (1994) (6)
- Cell biology. Fusion without SNAREs? (2001) (6)
- Prohormone structure governs proteolytic processing and sorting in the Golgi complex. (1993) (6)
- Analysis of neuropeptides using capillary zone electrophoresis with multichannel fluorescence detection (1991) (5)
- A bag cell neuron-specific antigen localizes to a subset of dense core vesicles in Aplysia california (1989) (5)
- Proteolytic processing of the Aplysia A peptide precursor in AtT-20 cells. (1994) (3)
- Addressing the accuracy of direct-to-consumer genetic testing (2019) (3)
- SELF-ASSOCIATION OF THE H3 REGION OF SYNTAXIN 1A: IMPLICATIONS FOR SNARE COMPLEX ASSEMBLY (2001) (3)
- Site-specific conjugation of cytotoxic drugs to antibodies substantially improves the therapeutic window (2008) (2)
- Molecular analysis of proteins associated with the synaptic vesicle membrane. (1990) (2)
- Small Cardioactive Peptides A and B (1987) (2)
- Neuropeptide Gene Expression and Behavior in Aplysia (1985) (1)
- Erratum: rab15, A novel low molecular weight GTP-binding protein specifically expressed in rat brain (The Journal of Biological Chemistry (1992) 267 (5768-5775)) (1992) (1)
- Crystal structure of the neuronal-sec1/syntaxin 1a complex (2000) (1)
- Patch Clamp Detection of Neuroreceptor Modulators in Capillary Electrophoresis (1997) (1)
- In situ Hybridization to Study the Origin and Fate of Identified Neurons (2019) (1)
- Why Cabilly must stand (2007) (1)
- ThioMabs: improving safety abd retaining efficacy of antibody drug conjugates (2007) (1)
- Chapter 3 Aplysia neuropeptides (1987) (1)
- Chapter 12 Regulation of Membrane Protein Organization at the Neuromuscular Junction (1996) (1)
- Vesicle trafficking and membrane fusion (1995) (0)
- Abstract 4396: Conjugation site modulates the stability and biological activity of antibody drug conjugates (2010) (0)
- Crystal structure of the RalA-GppNHp-Sec5 Ral-binding domain complex (2003) (0)
- Sec22b N-terminal domain (2001) (0)
- Introduction aux GSM et DCS (1993) (0)
- Aplysia neuroendocrine system (1986) (0)
- Identification of a 34 kDa protein specific to synaptic vesicles (1993) (0)
- Signalling mechanisms (1997) (0)
- Aplysia neuropeptides. (1987) (0)
- Isolation and characterization of a Drosophila neuropeptide gene. (2008) (0)
- The Molecular Mechanism of Intracellular Membrane Fusion (2010) (0)
- Engineering novel ThioFab/Mabs for site specific conjugation of cytotoxic drugs (2006) (0)
- The Evolution of FMRFamide-Like Neuropeptide Genes (1988) (0)
- The Expression of Neuropeptide Genes in Developing and Adult Neurons (1984) (0)
- Neuronal and glial cell biology Editorial overview (2000) (0)
- Crystal structure of the Ral-binding domain of Exo84 in complex with the active RalA (2005) (0)
- Correction: An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody–Drug Conjugate for the Treatment of Hormone Receptor–Positive Breast Cancer (2019) (0)
- Crystal structure and biophysical properties of a complex between the N-terminal region of SNAP25 and the SNARE region of syntaxin 1a (2001) (0)
- Signalling mechanisms. Editorial overview. (1997) (0)
- Abstracts of papers presented at the 1995 Meeting on Molecular & Behavioral Biology of Aplysia & Related Molluscs, April 19, 1995-April 23, 1995 (1995) (0)
- Mammalian SNAREs (1997) (0)
- Studies of Cloned Repetitive DNA Sequences in the Sea Urchin Genome (1980) (0)
- Down syndrome critical region proteinl (DSCR1), a novel VEGF target gene that regulates expression of COX-2 on activated endothelial cells (2005) (0)
- Revised structure of the munc18a-syntaxin1 complex (2008) (0)
- Evolution of Egg Laying Behavior in Aplysia (1986) (0)
- Sequence organization of repetitive dna sequence family members (1979) (0)
- Methodes et compositions de modulation de la secretion vesiculaire (1998) (0)
- Presynaptic component of LTP visualized at cultured CA3-CA1 synapses (1995) (0)
- Global change Plankton cooled a greenhouse (2000) (0)
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