Richard T. Walker
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(Suggest an Edit or Addition)Richard T. Walker's Published Works
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Published Works
- Comparative efficacy of antiherpes drugs against different strains of herpes simplex virus. (1980) (536)
- (E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent. (1979) (400)
- A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine. (1989) (356)
- Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors. (1996) (288)
- Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative. (1989) (269)
- Construction of the mycoplasma evolutionary tree from 5S rRNA sequence data. (1985) (159)
- Synthesis and antiviral activity of deoxy analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents. (1992) (146)
- Structure-activity relationships of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine analogues: effect of substitutions at the C-6 phenyl ring and at the C-5 position on anti-HIV-1 activity. (1992) (131)
- Thymidylate synthetase as target enzyme for the inhibitory activity of 5-substituted 2'-deoxyuridines on mouse leukemia L1210 cell growth. (1981) (128)
- Differential affinities of 5-(2-halogenovinyl)-2'-deoxyuridines for deoxythymidine kinases of various origins. (1981) (122)
- The synthesis of the potent anti-herpes virus agent, E-5(2-bromovinyl)-2′-deoxyuridine and related compounds (1979) (108)
- The synthesis and antiviral activity of some 4'-thio-2'-deoxy nucleoside analogues. (1991) (102)
- Synthesis and antiviral properties of 5-vinylpyrimidine nucleoside analogs. (1984) (91)
- Synthesis and antiviral properties of (E)-5-(2-bromovinyl)-2'-deoxycytidine-related compounds. (1988) (87)
- DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase. (1997) (75)
- Synthesis and anti-herpes virus activity of 2'-deoxy-4'-thiopyrimidine nucleosides. (1996) (70)
- Synthesis and anti-HIV activity of 2-, 3-, and 4-substituted analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT). (1991) (69)
- Highly potent and selective inhibition of human immunodeficiency virus type 1 by a novel series of 6-substituted acyclouridine derivatives. (1991) (67)
- Specific anti-HIV-1 "acyclonucleosides" which cannot be phosphorylated: synthesis of some deoxy analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine. (1991) (66)
- Nucleoside analogues : chemistry, biology, and medical applications (1979) (65)
- An investigation by 1H NMR spectroscopy into the factors determining the beta:alpha ratio of the product in 2'-deoxynucleoside synthesis. (1984) (61)
- Synthesis and biological properties of novel phosphotriesters: a new approach to the introduction of biologically active nucleotides into cells. (1990) (59)
- An improved synthesis of benzyl 3,5-di-O-benzyl-2-deoxy-1,4-dithio-d-erythro-pentofuranoside, an intermediate in the synthesis of 4′-thionucleosides (1992) (53)
- Comparative cytostatic activity of different antiherpetic drugs against herpes simplex virus thymidine kinase gene-transfected tumor cells. (1994) (53)
- Synthesis and antiviral activity of (E)-5-(2-bromovinyl)uracil and (E)-5-(2-bromovinyl)uridine. (1986) (50)
- Targets for the Design of Antiviral Agents (1984) (50)
- Isolation and Analysis of the Nucleic Acids and Polysaccharides from Clostridium welchii (1970) (49)
- Conformation of two 4'-thio-2'-deoxynucleoside analogs studied by 5000-MHz proton NMR spectroscopy and x-ray crystallography. (1992) (45)
- Isolation and Analysis of the Deoxyribonucleic Acid of Mycoplasma mycoides var. capri (1963) (45)
- Antiviral Drug Development (1988) (44)
- Studies on polynucleotides. CI. Escherichia coli tyrosine and formylmethionine transfer ribonucleic acids: effect of chemical modification of 4-thiouridine to uridine on their biological properties. (1972) (44)
- Synthesis and antiviral activity of 3'-deoxy-3'-C-hydroxymethyl nucleosides. (1990) (42)
- Relative potencies of different anti-herpes agents in the topical treatment of cutaneous herpes simplex virus infection of athymic nude mice (1979) (42)
- Synthetic analogues of polynucleotides—XIII: The resolution of dl-β-(thymin-1-yl)alanine and polymerisation of the β-(thymin-1-yl)alanines (1975) (41)
- Synthesis and antiviral activity of 6-benzyl analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents. (2010) (40)
- Highly potent and selective inhibition of HIV-1 replication by 6-phenylthiouracil derivatives. (1992) (38)
- The nucleotide sequence of the 5S rRNA from the archaebacterium Thermoplasma acidophilum. (1981) (37)
- The nucleotide sequence of the tRNAMMet from the archaebacterium Thermoplasma acidophilum. (1981) (36)
- Antiviral drug development : a multidisciplinary approach (1988) (36)
- Hept Derivatives: 6-Benzyl-1-ethoxymethyl-5-isopropyluracil (MKC-442) (1995) (34)
- Synthesis and properties of oligodeoxynucleotides containing the analogue 2′-deoxy-4′-thiothemidine (1993) (34)
- Synthesis and biological properties of some cyclic phosphotriesters derived from 2'-deoxy-5-fluorouridine. (1984) (33)
- The nucleotide sequence of formylmethionine tRNA from Mycoplasma mycoides sp. capri (1978) (33)
- Role of thymidine kinase in the inhibitory activity of 5-substituted-2'-deoxyuridines on the growth of human and murine tumor cell lines. (1982) (32)
- The synthesis and antiviral properties of (E)-5-(2-bromovinyl)-2'-deoxyuridine-related compounds (1987) (31)
- Incorporation of 5-substituted uracil derivatives into nucleic acids—III : Synthesis of 5-substituted uracils derived from 5-acetyluracil (1976) (31)
- Synthesis and antiviral properties of (Z)-5-(2-bromovinyl)-2'-deoxyuridine. (1981) (31)
- The synthesis of some branched-chain-sugar nucleoside analogues. (1987) (30)
- Formylatable methionine transfer RNA from Mycoplasma: purification and comparison of partial nucleotide sequences with those of other prokaryotic initiator tRNAs (1975) (30)
- Effect of human serum on the in vitro anti-HIV-1 activity of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) derivatives as related to their lipophilicity and serum protein binding. (1993) (30)
- Pharmacokinetics of E-5-(2-Bromovinyl)-2′-Deoxyuridine in Mice (1979) (30)
- The synthesis and antiviral properties of E-5-(2-bromovinyl)-4′-thio-2′-deoxyuridine (1991) (29)
- Investigation of some properties of oligodeoxynucleotides containing 4'-thio-2'-deoxynucleotides: duplex hybridization and nuclease sensitivity. (1996) (29)
- Synthesis and biological properties of 2'-deoxy-5-vinyluridine and 2'deoxy-5-vinylcytidine. (1982) (29)
- Synthesis and antiviral properties of some 2'-deoxy-5-(fluoroalkenyl)uridines. (1982) (27)
- The synthesis of nucleosides derived from 5-ethynyluracil and 5-ethynylcytosine (1979) (27)
- The chemical composition of the nucleic acids and other macromolecular constituents of Mycoplasma mycoides var. capri. (1965) (27)
- In vitro incorporation of eubacterial, archaebacterial and eukaryotic 5S rRNAs into large ribosomal subunits of Bacillus stearothermophilus. (1988) (25)
- The alkaline degradation of deoxyribonucleic acid derivatives (1968) (25)
- Antiviral, antimetabolic, and cytotoxic activities of 5-substituted 2'-deoxycytidines. (1982) (25)
- The synthesis and properties of some antiviral nucleosides (1978) (25)
- The crystal structure analysis of d(CGCGAASSCGCG)2, a synthetic DNA dodecamer duplex containing four 4'-thio-2'-deoxythymidine nucleotides. (1996) (24)
- Synergistic inhibition of human immunodeficiency virus type 1 replication by 5-ethyl-1-ethoxymethyl-6-(phenylthio)uracil (E-EPU) and azidothymidine in vitro (1991) (23)
- The chemistry of 2',3'-seconucleosides III. synthesis and reactions of purine-2',3'-secoribonucleosides (1988) (23)
- COMPARATIVE STUDY OF THE POTENCY AND SELECTIVITY OF ANTI-HERPES COMPOUNDS (1979) (22)
- Synthetic-analogues of polynucleotides XII. Synthesis of thymidine derivatives containing an oxyacetamido- or an oxyformamido-linkage instead of a phosphodiester group. (1974) (22)
- Synthesis and biological evaluation of some cyclic phosphoramidate nucleoside derivatives. (1990) (22)
- COMPARATIVE STUDY OF THE POTENCY AND SELECTIVITY OF ANTI-HERPES COMPOUNDS (1979) (22)
- 66. The nucleotide sequence in deoxyribonucleic acids. Part VI. The preparation and reactions of permanganate-oxidised deoxyribonucleic acid (1964) (21)
- The chemistry of 2',3'-seconucleosides IV. Synthesis and reactions of 3'-azido-2',3'-dideoxy-2',3'- secothymidine and related analogues (1990) (21)
- E. coli tyrosine transfer RNA: chemical modification of thiouridine to uridine. (1970) (21)
- Synthesis of 2′-deoxy-5-fluoro-5′-O-1″,3″,2″-oxazaphosphacyclohexa-2″-yluridine 2″-oxide and related compounds (1980) (20)
- A mild procedure for the anomerization of 2′-deoxynucleosides (1993) (20)
- The nucleotide sequence of glycine tRNA from Mycoplasma mycoides sp. capri. (1980) (20)
- The synthesis and biological properties of some aryl bis(nucleosid-5'-YL) phosphates using nucleosides with proven anti-HIV activity (1992) (19)
- Synthesis and antiviral activity of some 3'-C-difluoromethyl and 3'-deoxy-3'-C-fluoromethyl nucleosides. (1990) (19)
- Chemotherapeutic agents for herpesvirus infections. (1986) (19)
- The Synthesis of 4′-t-Butylcarbamyl- and 4′-p-Toluenesulphonamidyl-2′,3′-Dideoxy Pyrimidine Nucleoside Analogues (1994) (19)
- The use of fluorine-containing carboxylic acids for the large-scale isolation of highly polymerized deoxyribonucleic acids. (1966) (18)
- Synthesis of some analogues of 1-[(2-hydroxyethoxy)-methyl]-6-(phenylthio)thymine (hept) which have different types of acyclic structures (1992) (18)
- 4′-Methyloxycarbamyl-3′-deoxy-5-methyluridine; synthesis of a novel nucleoside analogue (1995) (18)
- Synthetic analogues of polynucleotides. X. The synthesis of poly-(3'-O-carboxymethyl-2'-deoxyadenosine) and its interaction with polynucleotides. (1973) (17)
- Synthesis of some 5-halogenovinyl derivatives of uracil and their conversion into 2′-deoxyribonucleosides (1981) (17)
- Lithiation of Uracilnucleosides and its Application to the Synthesis of a New Class of Anti-HIV-1 Acyclonucleosides (1991) (16)
- Anti-(herpes simplex virus) activity of 4'-thio-2'-deoxyuridines: a biochemical investigation for viral and cellular target enzymes. (2000) (16)
- SYNTHESIS AND BIOLOGICAL PROPERTIES OF A NEW SERIES OF 5-SUBSTITUTED-PYRIMIDINE-L-NUCLEOSIDE ANALOGUES (1998) (16)
- The synthesis of peptides containing purine and pyrimidine derivatives of DL-alanine (1974) (16)
- Incorporation of 5-substituted uracil derivatives into nucleic acids. Part IV. The synthesis of 5-ethynyluracil. (1976) (16)
- Synthetic analogues of polynucleotides. VI. The synthesis of ribonucleoside dialdehyde derivatives of polyacrylic acid hydrazide and their interaction with polynucleotides. (1971) (16)
- The nucleotide sequence of the 5S rRNA from Spiroplasma species BC3 and Mycoplasma mycoides sp. capri PG3. (1982) (16)
- Substrate specificity of DNA polymerases. I. Enzyme-catalysed incorporation of 5-'1-alkenyl)-2'-deoxyuridines into DNA. (1987) (16)
- Synthesis, properties, and biological activity of some nucleoside cyclic phosphoramidates (1984) (16)
- The action of alkali on some pyrimidines and their derivatives (1966) (16)
- Incorporation of 5-substituted uracil derivatives into nucleic acids—I (1973) (15)
- Some intramolecular rearrangements when pentofuranoses are treated with diethylaminosulphur trifluoride (DAST) (1993) (15)
- Sister chromatid exchange induced by anti-herpes drugs. (1981) (15)
- The chemical composition of the nucleic acids and the proteins of some mycoplasma strains. (1968) (15)
- The Synthesis of Some 5-Substituted and 5,6-Disubstituted 2′-Deoxyuridines (1994) (14)
- Selective anti-herpes activity of 5-(2-halogenovinyl)-2'-deoxyuridines and 2'-deoxycytidines (1981) (14)
- The nucleotide sequence of a tRNA gene cluster from Spiroplasma meliferum. (1986) (14)
- Polynucleotide analogue inhibition of messenger-stimulated transfer RNA binding to ribosomes. (1971) (14)
- Nucleoside Analogues (1979) (14)
- A simple method for the preparation of 'ribonucleoside dialdehydes' and some comments on their structure. (1976) (14)
- Synergistic inhibition of human immunodeficiency virus type 1 (HIV-1) replication in vitro by 1-[(2-hydroxyethoxy)methyl]-6-phenylthiothymine (HEPT) and recombinant alpha interferon. (1991) (13)
- SOME REACTIONS OF 4'-THIONUCLEOSIDES AND THEIR SULFONES (1996) (13)
- Some 6-aza-5-substituted-2'-deoxyuridines show potent and selective inhibition of herpes simplex virus type 1 thymidine kinase. (1998) (12)
- Kinetics for the Acid-Catalyzed Hydrolysis of Purine and Cytosine 2′-Deoxy-4′-thionucleosides (1999) (12)
- Nucleotide Sequence in Deoxyribonucleic Acids: The Determination of the Distribution of Adenine Residues (1964) (12)
- Palladium-catalysed carbomethoxyvinylation and thienylation of 5-iodo(bromo)-2,4-dimethoxypyrimidine in water (1997) (12)
- Design and Synthesis of Regioisomeric Analogues of a Specific Anti-HIV-1 Agent 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) (1994) (12)
- 4′-Thio-2′-deoxyribonucleosides: Their Chemistry and Biological Properties - A Review (1997) (12)
- The structure of the "uridine dialdehyde"-benzoylhdrazine reaction product. (1973) (11)
- Synthesis and Anti‐HIV Activity of 2‐, 3‐, and 4‐Substituted Analogues of 1‐((2‐Hydroxyethoxy)methyl)‐6‐(phenylthio)thymine (HEPT). (1991) (11)
- The chemistry of 2' ,3'-seconucleosides II. Reactions and biological properties of 2',3'-secopyrimidine ribonucleosides (1985) (11)
- Synthetic analogues of polynucleotides. Part 15. The synthesis and properties of poly(5′-amino-3′-O-carboxymethyl-2′,5′-dideoxy-erythro-pentonucleosides) containing 3′(O)→ 5′(C) acetamidate linkages (1979) (11)
- The synthesis and properties of some 5-substituted uracil derivatives. (1980) (11)
- 669. The permanganate oxidation of nucleosides (1963) (10)
- The synthesis and crystal structure of 5-acetyl-2'-deoxyuridine (1980) (10)
- SYNTHESIS AND ANTIVIRAL PROPERTIES OF 5-VINYLPYRIMIDINE NUCLEOSIDE ANALOGS (1985) (10)
- Studies on the deoxyribonucleic acid of Serratia marcescens. (1963) (10)
- Synthesis of some nucleoside cyclic phosphoramidates and related compounds via phosphoramidites (1985) (10)
- DUPLEX- AND TRIPLEX-FORMING PROPERTIES OF 4′-THIO-MODIFIED OLIGODEOXYNUCLEOTIDES (1997) (10)
- Chemical Degradation of DMA oxidized by Permanganate (1967) (10)
- A method for the rapid preparation of 5-vinyluracil in high yield. (1974) (10)
- Efficient syntheses of (E)-5-(2-bromovinyl)-2'-deoxy-4'-thiouridine; a nucleoside analogue with potent biological activity. (1998) (10)
- Synthetic analogues of polynucleotides. Part VIII. Analogues of oligonucleotides containing carboxymethylthymidine (1972) (9)
- Antiviral nucleic acid derivatives. III. Crystal structure of 5-ethynyl-2'-deoxyuridine (1978) (9)
- The synthesis of difluoro and trifluoro analogues of pyrimidine deoxyribonucleosides: a novel approach using elemental fluorine (1994) (9)
- Use of Acidic Degradation for the Determination of the Distribution of Pyrimidine Nucleotides in Deoxyribonucleic Acids (1966) (9)
- Synthesis and hydrolytic stability of the α and β anomers of 4′-thio-2′-deoxyuridine and their 5-substituted analogs. Competition between the acid-catalysed depyrimidination and isomerisation to a 5-thiopyranoside nucleoside (1998) (9)
- The permanganate oxidation of cytosine derivatives (1971) (9)
- Incorporation of 5-substituted uracil derivatives into nucleic acids. II. Incorporation of 5-vinyluracil into the DNA of Escherichia coli. (1973) (8)
- Synthetic analogues of polynucleotides. (Part) XIV. The synthesis of poly (3'-0-carboxymethyl-2'-deoxycytidine) and its interaction with polyinosinic acid. (1975) (8)
- A New Class of HIV‐1‐Specific 6‐Substituted Acyclouridine Derivatives: Synthesis and Anti‐HIV Activity of 5‐ or 6‐Substituted Analogues of 1‐( (2‐Hydroxyethoxy)methyl)‐6‐(phenylthio)thymine (HEPT). (1991) (8)
- Distribution of Adenine Residues in Deoxyribonucleic Acids (1964) (8)
- Solution structures of some ‘uridine dialdehyde’ derivatives (1984) (8)
- A Spiroplasma tRNA gene cluster. (1984) (8)
- The synthesis of some 5-vinyluracil-nucleoside analogues (1991) (8)
- Some novel nucleoside rearrangements effected by (diethylamino)sulphur trifluoride: synthesis and antiviral properties of some fluorine-containing 3′-azido-3′-deoxythymidine derivatives (1993) (7)
- E-5-(2-Chlorovinyl)-2′-Deoxycytidine: Synthesis and Antiherpetic Activity (1990) (7)
- The preparation of 5-cyanouracil and 5-cyano-2'-deoxyuridine from the corresponding 5-iodo derivative and cuprous cyanide. (1975) (7)
- Synthesis of 5-ethynylcytosine and 5-ethynylcytidine (1977) (7)
- Study of the use of alkaline degradation of DNA derivative as a procedure for the determination of nucleotide distribution. (1968) (7)
- Some chemical reactions of 5-vinyluracil and 2′-deoxy-5-vinyluridine (1987) (7)
- The chemical synthesis and x-ray structure of the sulfone of 4′-thiothymidine (1994) (7)
- Synthetic analogues of polynucleotides. Part VII. Further syntheses of 5′-O-acryloylnucleosides and copolymers of these with other acryloyl compounds (1971) (7)
- The Synthesis of 5-Substituted-2, 4-dimethoxypyrimidines and Some Related Nucleoside Analogues (1992) (7)
- A comparison of the conformations adopted by some 5-bromovinyl-2'-deoxyuridines and a correlation with their antiviral properties: an X-ray study. (1987) (6)
- Synthesis and Anti‐Herpes Virus Activity of 2′‐Deoxy‐4′‐thiopyrimidine Nucleosides. (1996) (6)
- Synthetic analogues of polynucleotides. Part IX. Synthesis of 3′-O-carboxymethyl-2′-deoxyribonucleosides and their use in the synthesis of an analogue of 2′-deoxyadenylyl-(3′→ 5′-)-thymidine 3′-phosphate (1973) (6)
- Migration and stability of the silyl group in the use of phenylthiomethyltrimethylsilane as a formyl synthon (1988) (6)
- Synthesis of two diastereoisomeric p-nitrophenyl phosphodiesters of 2', 3'-secouridine and their affinity for phosphodiesterases (1986) (6)
- A novel method for deuteration of 2′-deoxy-4′-thionucleosides (1998) (6)
- Relative Potencies ofDifferent Anti-Herpes Agents inthe Topical Treatment ofCutaneous Herpes Simplex Virus Infection ofAthymic NudeMice (1979) (6)
- DNA Homology of Two Mycoplasma Species (1967) (6)
- The phototransformation of 5-tert-butyl-2′-deoxyuridine: anapproach to the synthesis of new1,2-dihydrocyclobuta[d]pyrimidin-2-ones1 (1997) (6)
- Synthesis of 5-(1-substituted ethyl)uracil derivatives and some of their chemical and biological properties (1987) (6)
- Antiviral nucleic acid derivatives. II. Crystal structure of 5‐vinyl‐2'‐deoxyuridine (1978) (5)
- Synthesis and properties of oligodeoxynucleotides containing the analogue 2'-deoxy-4'-thiothymidine. (1993) (5)
- Mycoplasma evolution: a review of the use of ribosomal and transfer RNA nucleotide sequences in the determination of phylogenetic relationships. (1983) (5)
- The reaction of 4-thiouridine with cyanogen bromide (1971) (5)
- Synthesis of derivatives of methyl 3-deoxy-3-C-formyl-α-d-arabino-pentofuranoside (1992) (5)
- HEPT: From an Investigation of Lithiation of Nucleosides Towards a Rational Design of Non-Nucleoside Reverse Transcriptase Inhibitors of HIV-1 (2000) (5)
- The Synthesis of Some 5-Alkyl (Cycloalkyl)-Substituted 2′ -Deoxy-4′-Thiouridines (1996) (5)
- The crystal and molecular structure of a-5-acetyl-2'-deoxyuridine (1977) (5)
- 4′-Thio-5-Ethyl-2′-Deoxyuridine5′-Triphosphate (TEDUTP): Synthesis and Substrate Properties in DNA-Synthesizing Systems (1996) (5)
- Stereoselective synthesis of novel 1′-substituted 2′-deoxy-4-thionucleosides (1999) (5)
- The Synthesis of Some 5-Substituted-6-aza-2′-deoxyuridines (1994) (4)
- Bromovinyluracil nucleoside analogues as antiherpes agents (1984) (4)
- The synthesis of novel 6-substituted acyclouridine derivatives which show specific inhibition of HIV-1 (1990) (4)
- Preparation of a stable mercury derivative of tyrosine transfer RNA. (1973) (4)
- The synthesis and antiviral activity of some 4'-thio-2'-deoxynucleoside analogues. (1991) (4)
- The isolation of nucleic acids from gram-positive bacteria. (1968) (4)
- The selective acylation of the functional groups of cytidine and 2′-deoxycytidine (1975) (4)
- THE SYNTHESIS OF THE POTENT ANTIHERPES VIRUS AGENT, E-5(2-BROMOVINYL)-2′-DEOXYURIDINE AND RELATED COMPOUNDS (1980) (4)
- Biosynthetic Precursors of Some Modified Nucleosides in the Transfer Ribonucleic Acid of Mycoplasma mycoides var. capri (1971) (4)
- The isolation, analysis and chemical reactions of deoxyribonucleic acid (DNA)—II.: The analysis of DNA (1967) (4)
- Organization and structure of tRNA genes in Spiroplasma melliferum. (1987) (4)
- Design and Synthesis of Regioisomeric Analogues of a Specific Anti‐HIV‐ 1 Agent 1‐((2‐Hydroxyethoxy)methyl)‐6‐(phenylthio)thymine (HEPT). (1995) (4)
- Synthesis and properties of poly(5-ethynyluridylic acid) (1980) (4)
- Ribonucleosides and ribonucleotides derived from 5-acetyluracil (1979) (4)
- The action of alkali on some 9-substituted adenines (1968) (4)
- Trichomonas vaginalis thymidine kinase: purification, characterization and search for inhibitors. (1998) (4)
- INCORPORATION OF 5-SUBSTITUTED URACIL DERIVATIVES INTO NUCLEIC ACIDS PART 1, SYNTHESIS OF SOME 5-SUBSTITUTED URACILS (1973) (3)
- The isolation, analysis and chemical reactions of deoxyribonucleic acid [DNA]—III. The chemical reactions of DNA☆ (1968) (3)
- An efficient and general synthesis of 5'-esters of 2',3'-didehydro-2',3'-dideoxynucleosides : a facile opening of 2',3'-orthoacetates of ribonucleosides followed by reductive elimination of the halogenoacetates (1993) (3)
- Inhibition of the Herpes Simplex Virus Thymidine Kinase by 5 Substituted Thymidine Analogues. Comparison of the Types 1 and 2 Enzymes (1988) (3)
- Synthesis of a potential photoaffinity labelling reagent for HIV-1 reverse transcriptase (1993) (3)
- Synthetic analogues of polynucleotides. Part III. The synthesis and polymerisation of 2′,3′-O-isopropylidene-5′-O-(3-vinylacryloyl)uridine (1968) (3)
- The Synthesis and Antiviral Activity of (E)-5-(2-Nitrovinyl)uridine and (E)-5-(2-Nitrovinyl)-2′-deoxyuridine (1992) (3)
- Synthesis and Biological Properties of Some Cyclic Phosphotriesters Derived from 2′-Deoxy-5-fluorouridine. (1984) (3)
- Synthesis of some analogues of nucleoside 5′-triphosphates (1984) (3)
- The establishment of an equilibrium between α- and β-2'-deoxynucleosides (1993) (2)
- THE SYNTHESIS, STRUCTURE AND PROPERTIES OF A 1,2-DIHYDROPYRIMIDIN-2-ONE FORMED BY UV-IRRADIATION OF 5-T-BUTYL-1-METHYLURACIL (1996) (2)
- Some Reactions of 4′‐Thionucleosides and Their Sulfones. (1996) (2)
- Is there sometimes T-T wobble pairing in thymidylyl-3',5'-thymidine? (1984) (2)
- Synthetic analogues of polynucleotides. II. Studies on copolymers of 5'-O-acryloyluridine with acrylamide and their interaction with deoxyribonucleic acid. (1968) (2)
- Bacterial phylogeny with particular reference to Mycoplasma (1990) (2)
- The Synthesis of Ribosides of Asymmetrically-Substituted Aminohalogenobenzimidazoles (1988) (2)
- SYNTHETIC ANALOGUES OF POLYNUCLEOTIDES PART 12, SYNTHESIS OF THYMIDINE DERIVATIVES CONTAINING AN OXYACETAMIDO- OR AN OXYFORMAMIDO-LINKAGE INSTEAD OF A PHOSPHODIESTER GROUP (1974) (2)
- The synthesis of poly(acrylic acid hydrazide) and poly(methylacrylic acid hydrazide) and their reaction products with ribonucleoside dialdehydes (1976) (2)
- Prospects for the design of new antiviral molecules: a chemist's view. (1984) (2)
- The Chemistry of 2′,3′-Seconucleosides. Part 4. Synthesis and Reactions of 3′-Azido-2′,3′-dideoxy-2,′,3′-secothymidine and Related Analogues. (1990) (2)
- Incorporation of 5-substituted uracil derivatives into nucleic acids. The isolation and gamma-radiation-sensitivity of bacteriophage T3 containing the thymine analogue 5-vinyluracil. (1980) (2)
- 1144. The oxidation of nucleic acid derivatives by manganese dioxide (1963) (2)
- Efficient Syntheses of (E)-5-(2-Bromovinyl)-2′-deoxy-4′-thiouridine; a Nucleoside Analogue with Potent Biological Activity. (1998) (2)
- Pyrimidines and Quinazolines (1964) (2)
- The synthesis of some substituted-5-vinyluracilnucleoside analogues (1990) (1)
- Synthetic analogues of polynucleotides. 3. The synthesis and polymerisation of 2',3'-O-isopropylidene-5'-O-(3-vinylacryloyl)uridine. (1968) (1)
- The action of iodine on deoxyribonucleic acid. (1966) (1)
- 5-ethyl-2'-deoxy-4'-thiouridine (R)-S-oxide monohydrate. (2000) (1)
- SYNTHESIS OF SOME 5-HALOVINYL DERIVATIVES OF URACIL AND THEIR CONVERSION INTO 2′-DEOXYRIBONUCLEOSIDES (1981) (1)
- The isolation, analysis and chemical reactions of deoxyribonucleic acid (DNA)—I.: The isolation and purification of DNA (1967) (1)
- 5-Methyl-2′-deoxy-4′-thio-α-uridine (R)-S-oxide (2000) (1)
- Structure of two isomeric 1,3,2-dioxaphosphorinanes (1986) (1)
- The synthesis of some tritiated 5‐substituted uracil derivatives (1979) (1)
- Synthesis of asymmetrically substituted aminohalogenobenzimidazoles (1987) (1)
- SYNTHESIS OF SOME ANALOGS OF NUCLEOSIDE 5′-TRIPHOSPHATES (1984) (1)
- Use of alkali in a rapid procedure for the isolation of partly-degraded deoxyribonucleic acid: investigation of the method introduced by W. Jones. (1967) (1)
- Some 6-Aza-5-substituted-2′-deoxyuridines Show Potent and Selective Inhibition of Herpes Simplex Virus Type 1 Thymidine Kinase (1998) (1)
- The phototransformation of 5- tert -butyl-2'-deoxyuridine and 5- tert -butyl- N -1-methyluracil into their corresponding 4,5-cyclobutan-1,2-dihydropyrimidin-2-ones (1996) (1)
- HEPT Derivatives: 6-Benzyl-1-ethoxymethyl-5-isopropyluracil (MKC-442). (1995) (1)
- The Synthesis and Antiviral Activity of Some 4′‐Thio‐2′‐deoxy Nucleoside Analogues. (1992) (1)
- Antiviral Chemotherapy: Design or Serendipity ? (1987) (1)
- The sensitivity of Mycoplasma mycoides var. capri cells to gamma-radiation after growth in a medium containing the thymine analogue 5-vinyluracil. (1979) (1)
- SYNTHETIC ANALOGUES OF POLYNUCLEOTIDES PART 13, THE RESOLUTION OF DL-BETA-(THYMIN-1-YL)ALANINE AND POLYMERISATION OF THE BETA-(THYMIN-1-YL)ALANINES (1975) (1)
- INCORPORATION OF 5-SUBSTITUTED URACIL DERIVATIVES INTO NUCLEIC ACIDS. III. SYNTHESIS OF 5-SUBSTITUTED URACILS DERIVED FROM 5-ACETYLURACIL (1977) (1)
- Some Chemical Reactions of 5‐Vinyluracil and 2′‐Deoxy‐5‐vinyluridine. (1987) (1)
- SYNTHESIS AND ANTIVIRAL PROPERTIES OF (Z)-5-(2-BROMOVINYL)-2′-DEOXYURIDINE (1981) (1)
- Chemical degradation of DNA oxidized by permanganate. (1967) (1)
- Synthetic analogues of polynucleotides. 8. Analogues of oligonucleotides containing carboxymethylthymidine. (1972) (0)
- Construction of the mycoplasma ev sequence data (acholeplasma/anaeroplasma/spiroplasma/ureaplasma) (2016) (0)
- The potential for therapeutic use of oligomers containing 4-thio-2-deoxyribonucleosides (1995) (0)
- New deoxycytidine compounds, their preparation and pharmaceutical preparations containing them (1980) (0)
- The Synthesis of Some 5‐Substituted‐6‐aza‐2′‐deoxyuridines. (1995) (0)
- A Mild Procedure for the Anomerization of 2′-Deoxynucleosides. (1994) (0)
- Synthesis and Antiviral Activity of Some 3′‐C‐Difluoromethyl and 3′‐ Deoxy‐3′‐C‐fluoromethyl Nucleosides. (1991) (0)
- The nucleotide sequence of the SS rRNA from the archaebacterium Thermoplasma addophilum (2005) (0)
- The Chemistry of 2′,3′‐Seconucleosides. Part 2. Reactions and Biological Properties of 2′,3′‐Secopyrimidine Ribonucleosides. (1986) (0)
- An Efficient and General Synthesis of 5′-Esters of 2′,3′-Didehydro-2′, 3′-dideoxynucleosides: A Facile Opening of 2′,3′-Orthoacetates of Ribonucleosides Followed by Reductive Elimination of the Halogenoacetates. (1993) (0)
- The Synthesis and Antiviral Properties of E‐5‐(2‐Bromovinyl)‐4′‐thio‐2′ ‐deoxyuridine. (1991) (0)
- 4′-Methyloxycarbamyl-3′-deoxy-5-methyluridine; Synthesis of a Novel Nucleoside Analogue. (1995) (0)
- Incorporation of 5-substituted uracil derivatives into nucleic acids. The synthesis of 5 -ethynyluracil. (0)
- E-5- (2-halogenovinyl) -2'-desoxycytydines; their process for the preparation and their use in pharmaceutical compositions for the treatment of virus diseases (1980) (0)
- Synthesis of novel 6-substituted acyclouridine derivatives and their anti-HIV-1 activity. (1990) (0)
- The synthesis and biological properties of some 5-substituted-2'-deoxyuridines. (1985) (0)
- The Synthesis of Some 5-Substituted and 5,6-Disubstituted 2′- deoxyuridines. (2010) (0)
- SYNTHESIS OF 2′-DEOXY-5-FLUORO-5′-O-1′′,3′′,2′′-OXAZAPHOSPHACYCLOHEXA-2′′-YLURIDINE 2′′-OXIDE AND RELATED COMPOUNDS (1981) (0)
- A SIMPLE METHOD FOR THE PREPARATION OF ′RIBONUCLEOSIDE DIALDEHYDES′ AND SOME COMMENTS ON THEIR STRUCTURE (1976) (0)
- Synthesis and Antiviral Activity of 3′‐Deoxy‐3′‐C‐hydroxymethyl Nucleosides. (1991) (0)
- Synthesis of 5-(1-Substituted Ethyl)uracil Derivatives and Some of Their Chemical and Biological Properties. (1987) (0)
- The Chemistry of 2′,3′-Seconucleosides. Part 1. Synthesis and Chemical and Biological Properties of Derivatives of 2′,3′-Secouridine. (1986) (0)
- Synthesis and antiviral activity of some 3'-C-hydroxymethyl-, 3'-C-difluoromethyl- and 3'-C-fluoromethyl-3'-deoxynucleosides (1990) (0)
- Some novel pyrimidine nucleoside rearrangements effected by diethylaminosulfur trifluoride (DAST). (1992) (0)
- Nucleic Acids Research In vitro incorporation of enbacteriai , archaebacterial and eukaryotk 5 S rRNAs into large ribosomal subunhs of Bacillus stearothennophilus (2005) (0)
- The purification of the initiator tRNA from an Archaebacterial species, Thermoplasma acidophilum (1981) (0)
- The synthesis and some properties of some 5-substituted pyrimidine 4'-thio-2'-deoxynucleosides and oligodeoxynucleotides containing 4'-thiothymidine. (1993) (0)
- α‐5‐Adamantyl‐4'‐thio‐2'‐deoxyuridine Methanol Solvate (1996) (0)
- SYNTHETIC ANALOGS OF POLYNUCLEOTIDES. PART 15. THE SYNTHESIS AND PROPERTIES OF POLY(5′-AMINO-3′-O-CARBOXYMETHYL-2′,5′-DIDEOXY-ERYTHRO-PENTONUCLEOSIDES) CONTAINING 3′(O) → 5′(C) ACETAMIDATE LINKAGES (1979) (0)
- Acyclic 6-substituted pyrimidine nucleoside derivatives and antiviral agents containing the same as active agent. (1989) (0)
- Synthetic analogues of polynucleotides. IX. Synthesis of 3'-O-carboxymethyl-2'-deoxyribonucleosides and their use in the synthesis of an analogue of 2'-deoxyadenylyl-(3' leads to 5'-)-thymidine 3'-phosphate. (1973) (0)
- The Chemistry of 2′,3′-Seconucleosides. Part 3. Synthesis and Reactions of Purine-2,′3′-secoribonucleosides. (1989) (0)
- SOLUTION STRUCTURES OF SOME URIDINE DIALDEHYDE DERIVATIVES (1984) (0)
- Synthesis of two diastereoisomerk p-nitrophenyl phosplodiesters of 2',3' secouridine and their affnity for phosphodiesterases' (0)
- The Synthesis of Difluoro and Trifluoro Analogues of Pyrimidine Deoxyribonucleosides: A Novel Approach Using Elemental Fluorine. (1995) (0)
- The Synthesis of 4′-tert-Butylcarbamyl- and 4′-p-Toluenesulfonamidyl-2′ ,3′-dideoxy Pyrimidine Nucleoside Analogues. (1995) (0)
- FormyUtable methionine transfer RNA from Mycoplasma : purification and comparison of partial nucleotide sequences with those of other prokaryotlc initiator tRNAs (0)
- Some Intramolecular Rearrangements when Pentofuranoses are Treated with Diethylaminosulfur Trifluoride (DAST). (1994) (0)
- The synthesis and properties of some 5-substituted uracil derivatives. (1981) (0)
- SYNTHESIS AND ANTIVIRAL PROPERTIES OF SOME 2′-DEOXY-5-(FLUOROALKENYL)URIDINES (1983) (0)
- The Phototransformation of 5‐tert‐Butyl‐2′‐deoxyuridine: An Approach to the Synthesis of New 1,2‐Dihydrocyclobuta(d)pyrimidin‐2‐ones. (1997) (0)
- Archaebacteria—the third kingdom (1990) (0)
- THE SYNTHESIS OF A POTENTIALLY METABOLICALLY-LABILE DERIVATIVE OF 2′-DEOXY-5-FLUOROURIDINE 5′-PHOSPHATE (1980) (0)
- Antiviral Chemotherapy: An Introduction and Reasons for the Slow Progress, Particularly towards Rational Design (1988) (0)
- The reaction of dihydroxyacetone with ethanedithiol. Synthesis and x-ray crystal structure of 1,4,7,10-tetrathiaspiro[5.5]undecane (1983) (0)
- COMPOSITIONS AND METHOD OF USE (2017) (0)
- In vitro incorporation of enbacteriai, archaebacterial and eukaryotk 5S rRNAs into large ribosomal subunhs of Bacillus stearothennophilus (1988) (0)
- DNA containing 4 (cid:1) -thio-2 (cid:1) -deoxycytidine inhibits methylation by HhaI methyltransferase (1997) (0)
- The Structure of Two Isomeric 1,3,2-Dioxaphosphorinanes (I) and (II). (1987) (0)
- Nato International advanced study institute on targets for the design of antiviral agents (1982) (0)
- Stereoselective Synthesis of Novel 1′-Substituted 2′-Deoxy-4-thionucleosides. (1999) (0)
- Some Novel Nucleoside Rearrangements Effected by (Diethylamino)sulfur Trifluoride: Synthesis and Antiviral Properties of Some Fluorine‐ Containing 3′‐Azido‐3′‐deoxythymidine Derivatives. (1994) (0)
- The synthesis and antiviral properties of some 5-substituted 2-deoxy-4-thiopyrimidine nucleosides (1994) (0)
- Synthesis and Biological Properties of a New Series of 5-Substituted-pyrimidine-L-nucleoside Analogues. (1999) (0)
- THE SYNTHESIS AND CRYSTAL STRUCTURE OF 5-ACETYL-2′-DEOXYURIDINE (1980) (0)
- 5-Methyl-2′-deoxy-4′-thio-α-uridine (R)-S-Oxide (2001) (0)
- The Chemical Synthesis and X‐Ray Structure of the Sulfone (IV) of 4′‐ Thiothymidine. (1994) (0)
- Invitro incorporation ofeubacterial, archaebacterial andeukaryotic 5SrRNAsintolarge ribosomal subunits ofBacillus stearothermophilus (1988) (0)
- The Synthesis, Structure and Properties of a 1,2‐Dihydropyrimidin‐2‐ one Formed by UV‐Irradiation of 5‐t‐Butyl‐1‐methyluracil. (1996) (0)
- 5-Methyl-2'-deoxy-4'-thio-alpha-uridine (R)-S-oxide. (2000) (0)
- New chemical compounds, processes for their preparation and their use as medicine with antiviral effective (1979) (0)
- Synthesis of Asymmetrically Substituted Aminohalogenobenzimidazoles. (1988) (0)
- Palladium-Catalyzed Carbomethoxyvinylation and Thienylation of 5-Iodo( Bromo)-2,4-dimethoxypyrimidine in Water. (1997) (0)
- Synthesis of Nucleoside Analogues with Potential Antiviral Activity against Negative Strand RNA Virus Targets (1989) (0)
- The preparation and properties of a stable mercury derivative of transfer RNAs from Escherichia coli. (1974) (0)
- Nucleic Acids Research An Investigation by 1H NMR spectroscopy Into the factors determining the .3:a ratio of the product An invesdigatfion by IH NMOR spectrosopy inlto the factors determhing the #B:a ratfio of the product In 2' deoxynu s ynthe (0)
- The synthesis and antiviral properties of some 2′-deoxy-4′-thio-ribonucleoside analogues (1991) (0)
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