Richard T. Wyatt
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Biology
Richard T. Wyatt's Degrees
- PhD Neuroscience Stanford University
- Masters Biology Stanford University
- Bachelors Biology Stanford University
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(Suggest an Edit or Addition)Richard T. Wyatt's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody (1998) (3032)
- The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens. (1998) (1680)
- Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1 (2010) (1653)
- The antigenic structure of the HIV gp120 envelope glycoprotein (1998) (1312)
- CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5 (1996) (1240)
- HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites (2002) (924)
- A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding. (1998) (901)
- Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals (2009) (869)
- HIV vaccine design and the neutralizing antibody problem (2004) (835)
- Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 (2011) (827)
- Structural definition of a conserved neutralization epitope on HIV-1 gp120 (2007) (822)
- Broad and potent neutralization of HIV-1 by a gp41-specific human antibody (2012) (804)
- Structure of a V3-Containing HIV-1 gp120 Core (2005) (780)
- Tyrosine Sulfation of the Amino Terminus of CCR5 Facilitates HIV-1 Entry (1999) (681)
- Structure and Mechanistic Analysis of the Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5 in Complex with Its gp41 Epitope (2004) (492)
- Energetics of the HIV gp120-CD4 binding reaction. (2000) (462)
- Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding (1995) (453)
- Proof of principle for epitope-focused vaccine design (2014) (446)
- Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4 (2007) (423)
- Broad HIV-1 neutralization mediated by CD4-binding site antibodies (2007) (420)
- Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-120 interface (2014) (416)
- Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates. (2000) (410)
- Access of Antibody Molecules to the Conserved Coreceptor Binding Site on Glycoprotein gp120 Is Sterically Restricted on Primary Human Immunodeficiency Virus Type 1 (2003) (384)
- The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus (2008) (381)
- A Blueprint for HIV Vaccine Discovery. (2012) (372)
- Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility (2009) (351)
- Frequency and Phenotype of Human Immunodeficiency Virus Envelope-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies (2008) (348)
- A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples. (2010) (332)
- Breadth of Human Immunodeficiency Virus-Specific Neutralizing Activity in Sera: Clustering Analysis and Association with Clinical Variables (2009) (326)
- Selective Interactions of Polyanions with Basic Surfaces on Human Immunodeficiency Virus Type 1 gp120 (2000) (310)
- Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120 (2009) (307)
- Highly Stable Trimers Formed by Human Immunodeficiency Virus Type 1 Envelope Glycoproteins Fused with the Trimeric Motif of T4 Bacteriophage Fibritin (2002) (303)
- Oligomeric Modeling and Electrostatic Analysis of the gp120 Envelope Glycoprotein of Human Immunodeficiency Virus (2000) (302)
- Elicitation of structure-specific antibodies by epitope scaffolds (2010) (292)
- Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies (1994) (280)
- Analysis of Neutralization Specificities in Polyclonal Sera Derived from Human Immunodeficiency Virus Type 1-Infected Individuals (2008) (278)
- Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120. (2004) (267)
- Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein (1997) (251)
- Mechanism of Neutralization by the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 (2011) (240)
- Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches (2017) (236)
- Functional and immunologic characterization of human immunodeficiency virus type 1 envelope glycoproteins containing deletions of the major variable regions (1993) (233)
- A Tyrosine-Rich Region in the N Terminus of CCR5 Is Important for Human Immunodeficiency Virus Type 1 Entry and Mediates an Association between gp120 and CCR5 (1998) (230)
- Improved Elicitation of Neutralizing Antibodies against Primary Human Immunodeficiency Viruses by Soluble Stabilized Envelope Glycoprotein Trimers (2001) (213)
- A method for identification of HIV gp140 binding memory B cells in human blood. (2009) (209)
- Mutagenic Stabilization and/or Disruption of a CD4-Bound State Reveals Distinct Conformations of the Human Immunodeficiency Virus Type 1 gp120 Envelope Glycoprotein (2002) (192)
- Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition. (2003) (180)
- Characterization of Stable, Soluble Trimers Containing Complete Ectodomains of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins (2000) (178)
- Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design. (2015) (175)
- Characterization of Antibody Responses Elicited by Human Immunodeficiency Virus Type 1 Primary Isolate Trimeric and Monomeric Envelope Glycoproteins in Selected Adjuvants (2006) (171)
- Modifications That Stabilize Human Immunodeficiency Virus Envelope Glycoprotein Trimers in Solution (2000) (166)
- Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120. (2008) (158)
- Enhanced Expression, Native Purification, and Characterization of CCR5, a Principal HIV-1 Coreceptor* (1999) (149)
- Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage. (2005) (148)
- Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site (2015) (140)
- Structure-Based Stabilization of HIV-1 gp120 Enhances Humoral Immune Responses to the Induced Co-Receptor Binding Site (2009) (136)
- PGV04, an HIV-1 gp120 CD4 Binding Site Antibody, Is Broad and Potent in Neutralization but Does Not Induce Conformational Changes Characteristic of CD4 (2012) (130)
- Several GTP-binding proteins, including p21c-H-ras, are preferred substrates of Pseudomonas aeruginosa exoenzyme S. (1989) (119)
- Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers (2019) (118)
- CD4-independent binding of SIV gp120 to rhesus CCR5. (1997) (118)
- Characterization of Human Immunodeficiency Virus Type 1 Monomeric and Trimeric gp120 Glycoproteins Stabilized in the CD4-Bound State: Antigenicity, Biophysics, and Immunogenicity (2007) (117)
- Relationship between Antibody 2F5 Neutralization of HIV-1 and Hydrophobicity of Its Heavy Chain Third Complementarity-Determining Region (2009) (115)
- Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region (1992) (112)
- Probability Analysis of Variational Crystallization and Its Application to gp120, The Exterior Envelope Glycoprotein of Type 1 Human Immunodeficiency Virus (HIV-1)* (1999) (112)
- BCL2 oncogene translocation is mediated by a chi-like consensus (1992) (111)
- High-Resolution Definition of Vaccine-Elicited B Cell Responses Against the HIV Primary Receptor Binding Site (2012) (111)
- Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein (1997) (110)
- The Envelope Glycoprotein Ectodomains Determine the Efficiency of CD4+ T Lymphocyte Depletion in Simian– Human Immunodeficiency Virus–Infected Macaques (1998) (107)
- Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers (2015) (107)
- Solid-Phase Proteoliposomes Containing Human Immunodeficiency Virus Envelope Glycoproteins (2002) (105)
- High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells. (2016) (104)
- Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth. (2005) (103)
- Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant (2011) (99)
- Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins. (2005) (99)
- Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates (2010) (98)
- Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer (2018) (98)
- Rational modifications of HIV-1 envelope glycoproteins for immunogen design. (2007) (96)
- Mechanism of Human Immunodeficiency Virus Type 1 Resistance to Monoclonal Antibody b12 That Effectively Targets the Site of CD4 Attachment (2009) (96)
- Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic. (1999) (94)
- Well-Ordered Trimeric HIV-1 Subtype B and C Soluble Spike Mimetics Generated by Negative Selection Display Native-like Properties (2015) (93)
- Direct Antibody Access to the HIV-1 Membrane-Proximal External Region Positively Correlates with Neutralization Sensitivity (2011) (92)
- Selection Pressure on HIV-1 Envelope by Broadly Neutralizing Antibodies to the Conserved CD4-Binding Site (2012) (90)
- An Aptamer That Neutralizes R5 Strains of Human Immunodeficiency Virus Type 1 Blocks gp120-CCR5 Interaction (2005) (84)
- Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability (2019) (84)
- Immunogenicity of HIV-1 envelope glycoprotein oligomers (2009) (84)
- Stabilization of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Trimers by Disulfide Bonds Introduced into the gp41 Glycoprotein Ectodomain (1998) (82)
- B Cell Recognition of the Conserved HIV-1 Co-Receptor Binding Site Is Altered by Endogenous Primate CD4 (2008) (81)
- Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies. (1998) (81)
- Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign (2014) (81)
- Soluble Mimetics of Human Immunodeficiency Virus Type 1 Viral Spikes Produced by Replacement of the Native Trimerization Domain with aHeterologous Trimerization Motif: Characterization and Ligand Binding Analysis (2005) (78)
- Particulate Array of Well‐Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach (2017) (76)
- Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. (2016) (76)
- Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles. (2008) (72)
- Resistance to Argentine stem weevil in perennial ryegrass infected with endophytes producing different alkaloids. (1995) (70)
- Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies (2016) (70)
- Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein (2017) (70)
- Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity. (2020) (67)
- Virus‐like Particles Identify an HIV V1V2 Apex‐Binding Neutralizing Antibody that Lacks a Protruding Loop (2017) (64)
- Robust Neutralizing Antibodies Elicited by HIV-1 JRFL Envelope Glycoprotein Trimers in Nonhuman Primates (2013) (63)
- Human Immunodeficiency Virus Type 1 Env Trimer Immunization of Macaques and Impact of Priming with Viral Vector or Stabilized Core Protein (2008) (62)
- Altered differentiation is central to HIV-specific CD4+ T cell dysfunction in progressive disease (2019) (62)
- HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins (2012) (60)
- Factors limiting the immunogenicity of HIV-1 gp120 envelope glycoproteins. (2004) (60)
- Biochemically Defined HIV-1 Envelope Glycoprotein Variant Immunogens Display Differential Binding and Neutralizing Specificities to the CD4-binding Site* (2011) (59)
- Influence of Novel CD4 Binding-Defective HIV-1 Envelope Glycoprotein Immunogens on Neutralizing Antibody and T-Cell Responses in Nonhuman Primates (2009) (58)
- Anti-HIV B Cell Lines as Candidate Vaccine Biosensors (2012) (58)
- Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization1 (2009) (57)
- Structure-activity relationships in the binding of chemically derivatized CD4 to gp120 from human immunodeficiency virus. (2007) (54)
- Analysis of the interaction of antibodies with a conserved enzymatically deglycosylated core of the HIV type 1 envelope glycoprotein 120. (1998) (54)
- Antibody 17b binding at the coreceptor site weakens the kinetics of the interaction of envelope glycoprotein gp120 with CD4. (2001) (53)
- HIV type 1 Env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies. (2011) (53)
- Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization (2014) (53)
- Inhibition of HIV‐1 entry by antibodies: potential viral and cellular targets (2007) (52)
- Covalent Linkage of HIV-1 Trimers to Synthetic Liposomes Elicits Improved B Cell and Antibody Responses (2017) (49)
- CD4-Mimetic Small Molecules Sensitize Human Immunodeficiency Virus to Vaccine-Elicited Antibodies (2014) (47)
- Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140. (2008) (47)
- Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability (2016) (47)
- CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization. (2008) (47)
- Dense Array of Spikes on HIV-1 Virion Particles (2017) (45)
- Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model (2017) (44)
- Biochemical and Immunogenic Characterization of Soluble Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Trimers Expressed by Semliki Forest Virus (2005) (42)
- B Cells from Knock-in Mice Expressing Broadly Neutralizing HIV Antibody b12 Carry an Innocuous B Cell Receptor Responsive to HIV Vaccine Candidates (2013) (41)
- Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response (2017) (39)
- Energetics of the HIV gp 120-CD 4 binding reaction (2000) (39)
- Hyperglycosylated Stable Core Immunogens Designed To Present the CD4 Binding Site Are Preferentially Recognized by Broadly Neutralizing Antibodies (2014) (36)
- Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer (2018) (35)
- Tyrosine-sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry. (2008) (32)
- Structure-guided Alterations of the gp41-directed HIV-1 Broadly Neutralizing Antibody 2F5 Reveal New Properties Regarding its Neutralizing Function (2012) (31)
- Studies with monoclonal antibodies to the V3 region of HIV-1 gp120 reveal limitations to the utility of solid-phase peptide binding assays. (1994) (30)
- BLyS-Mediated Modulation of Naive B Cell Subsets Impacts HIV Env-Induced Antibody Responses (2012) (29)
- Structure-Guided Redesign Improves NFL HIV Env Trimer Integrity and Identifies an Inter-Protomer Disulfide Permitting Post-Expression Cleavage (2018) (29)
- Diverse Antibody Genetic and Recognition Properties Revealed following HIV-1 Envelope Glycoprotein Immunization (2015) (29)
- A biosensor-based approach toward purification and crystallization of G protein-coupled receptors. (2006) (29)
- Human Plasmacytoid Dendritic Cells Efficiently Capture HIV-1 Envelope Glycoproteins via CD4 for Antigen Presentation (2013) (29)
- Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis (2015) (28)
- Targeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of Entry (2018) (27)
- Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding (2016) (27)
- The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization (2019) (27)
- Cleavage-Independent HIV-1 Trimers From CHO Cell Lines Elicit Robust Autologous Tier 2 Neutralizing Antibodies (2018) (26)
- High-Resolution Longitudinal Study of HIV-1 Env Vaccine–Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence (2016) (26)
- A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly. (2010) (26)
- HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization (2014) (25)
- Immunization with Wild-Type or CD4-Binding-Defective HIV-1 Env Trimers Reduces Viremia Equivalently following Heterologous Challenge with Simian-Human Immunodeficiency Virus (2010) (24)
- Migration ofAntigen-Specific T Cells Away from CXCR4-Binding Human ImmunodeficiencyVirus Type 1gp120 (2004) (23)
- HIV-1 Envgp140 trimers elicit neutralizing antibodies without efficient induction of conformational antibodies. (2006) (21)
- Independent Expansion of Epitope-Specific Plasma Cell Responses upon HIV-1 Envelope Glycoprotein Immunization (2013) (20)
- Evolution of B cell analysis and Env trimer redesign (2017) (20)
- Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses (2019) (18)
- Immunization with Recombinant HLA Classes I and II, HIV-1 gp140, and SIV p27 Elicits Protection against Heterologous SHIV Infection in Rhesus Macaques (2011) (18)
- Calcium Phosphate Nanoparticle-Based Vaccines as a Platform for Improvement of HIV-1 Env Antibody Responses by Intrastructural Help (2019) (17)
- 147 Rational Design of Envelope Surface Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1 (2011) (17)
- Computational design of protein antigens that interact with the CDR H3 loop of HIV broadly neutralizing antibody 2F5 (2014) (17)
- Chemical cross-linking of HIV-1 Env for direct TLR7/8 ligand conjugation compromises recognition of conserved antigenic determinants. (2013) (16)
- Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization (2019) (16)
- Characterization of antibody responses to purified HIV-1 gp120 glycoproteins fused with the molecular adjuvant C3d. (2005) (16)
- HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING HUMAN ANTIBODY (1998) (15)
- Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation (2015) (14)
- Antigen-Specific Single B Cell Sorting and Monoclonal Antibody Cloning in Guinea Pigs (2019) (14)
- Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates (2010) (14)
- HIV-1 Cross-Reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Nonhuman Primates (2017) (13)
- An HIV-1 Env–Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes (2016) (13)
- Synthetic multivalent V3 glycopeptides display enhanced recognition by glycan-dependent HIV-1 broadly neutralizing antibodies. (2017) (12)
- Translocation Is Mediated by a x-like Consensus By (1992) (11)
- Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer (2018) (10)
- Phosphoserine acidic cluster motifs bind distinct basic regions on the μ subunits of clathrin adaptor protein complexes (2018) (9)
- Glutaraldehyde Cross-linking of HIV-1 Env Trimers Skews the Antibody Subclass Response in Mice (2017) (9)
- Small-Molecule CD 4 Mimics Interact with a Highly Conserved Pocket on HIV-1 gp 120 (2018) (9)
- Conformation of the HIV-1 gp 120 envelope glycoprotein. (1996) (7)
- HIV-1 envelope glycoprotein trimer immunogenicity elicited in the presence of human CD4 alters the neutralization profile. (2014) (6)
- Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment (2019) (5)
- Structure of the Core of the HIV-1 gp 120 Exterior Envelope Glycoprotein (1999) (5)
- Structure of HIV-1 gp120 with gp41-Interactive Region: Layered Architecture and Basis of Conformational Mobility (2009) (5)
- , Epitope 1 Antibody 2 F 5 in Complex with Its gp 41 Anti-Human Immunodeficiency Virus Type Structure and Mechanistic Analysis of the (2004) (5)
- Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization (2021) (4)
- Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model (2018) (4)
- HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation (2016) (4)
- Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates (2018) (3)
- Ligand accessibility to the HIV-1 Env co-receptor binding site can occur prior to CD4 engagement and is independent of viral tier category. (2018) (3)
- Correction: Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability (2016) (2)
- Kinetic Analysis of Monoclonal Antibody Binding to HIV-1 gp120-derived Hyperglycosylated Cores. (2015) (2)
- HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B (2000) (2)
- Analysis of Neutralization Specificities in Polyclonal Sera Derived from Human Immunodeficiency Virus Type 1-Infected Individuals (cid:1) (2008) (1)
- Correction for Chakrabarti et al., Robust Neutralizing Antibodies Elicited by HIV-1 JRFL Envelope Glycoprotein Trimers in Nonhuman Primates (2014) (1)
- Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes (2022) (1)
- Antigenicity, structure and immunogenicity of the HIV-1 trimeric envelope glycoprotein spike (2014) (0)
- Correction for Khan et al., “Targeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of Entry” (2019) (0)
- 2F5 Epitope scaffold ES2 (2010) (0)
- Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer (2018) (0)
- HIV neutralizing antibodies: relevance to pathogenesis and vaccines (2007) (0)
- Vaccine-elicited cross-neutralizing HIV antibodies directed to multiple sites of Env vulnerability following heterologous NFL trimer-liposome prime:boosting (2019) (0)
- HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T257S, V275C, S334A, S375W, Q428C, A433M) Complexed with CD4 and Antibody 17b (2007) (0)
- D-107 HIV Env trimer immunogen design and modification to elicit neutralizing antibodies (2018) (0)
- Serum recognition of the native trimer and effects of a key mutation in the CD4 binding loop. (2015) (0)
- Human Immunodeficiency Virus Type 1 Env Trimer Immunization of Macaques and Impact of Priming with Viral Vector or Stabilized Core Protein (cid:1) † (2008) (0)
- Sundling the HIV Primary Receptor Binding Site High-Resolution Definition of Vaccine-Elicited B Cell Responses Against (2012) (0)
- HIV Research for Prevention HIV R4P (2014) (0)
- Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 11mer epitope (2004) (0)
- Following Immunization Recognizing Distinct Structural Elements Glycoprotein-Specific B Cell Subsets Selective Expansion of HIV-1 Envelope (2009) (0)
- HIV-1 gp120 Envelope Glycoprotein(S334A) Complexed with CD4 and Antibody 17b (2007) (0)
- Coupling of HIV-1 gp120-derived Core Protein to Paramagnetic Beads and Adsorption Assays. (2015) (0)
- HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E268C, S334A, S375W) Complexed with CD4 and Antibody 17b (2007) (0)
- Structure of tyrosine-sulfated 412d antibody complexed with HIV-1 YU2 gp120 and CD4 (2007) (0)
- HIV-1 gp120 Envelope Glycoprotein (T257S, S334A, S375W) Complexed with CD4 and Antibody 17b (2007) (0)
- Access of antibody molecules to th conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary HIV-1 (2009) (0)
- Crystal structure of HIV-1 JR-FL gp120 core protein containing the third variable region (V3) complexed with CD4 and the X5 antibody (2005) (0)
- Overview of human plasmas and animal sera. (2015) (0)
- Resource Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches Graphical Abstract Highlights (0)
- Correction for Ingale et al., Hyperglycosylated Stable Core Immunogens Designed To Present the CD4 Binding Site Are Preferentially Recognized by Broadly Neutralizing Antibodies (2015) (0)
- Potentially neutralizing B cell clonotypes are eliminated at peripheral selection checkpoints (LYM6P.768) (2014) (0)
- Eliciting broadly neutralizing antibodies to human immunodeficiency virus could bring closer the goal of a successful AIDS vaccine. Here the International AIDS Vaccine Initiative Neutralizing Antibody Consortium discusses current approaches to overcome the problems faced. (2004) (0)
- Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C2221 (2009) (0)
- Glycoproteins via CD4 for Antigen Efficiently Capture HIV-1 Envelope Human Plasmacytoid Dendritic Cells (2013) (0)
- Crystal structure of human anti-HIV-1 gp120-reactive antibody 47e fab (2004) (0)
- Phosphoserine acidic cluster motifs in the cytoplasmic domains of transmembrane proteins bind distinct basic regions on the μ subunits of clathrin adaptor protein complexes (2018) (0)
- IgG-Switched Macaque B Cells Reveal a Single-Cell and Deep Sequencing of Karlsson Hedestam (2014) (0)
- HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E267C, S334A, S375W) Complexed with CD4 and Antibody 17b (2007) (0)
- Subsets Impacts HIV Env-Induced Antibody BLyS-Mediated Modulation of Naive B Cell Cancro and (2012) (0)
- Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE356, from a non-human primate (2014) (0)
- ResponsesImpacts HIV Env-Induced Antibody BLyS-Mediated Modulation of Naive B Cell (2017) (0)
- Corrigendum to “A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples” (2012) (0)
- Effects of temporary BLyS treatment of rhesus macaques (2017) (0)
- 2F5 Epitope scaffold elicited anti-HIV-1 monoclonal antibody 11F10 in complex with HIV-1 GP41 (2010) (0)
- THE HIV VACCINE PROBLEM : WHY HAVE PAST APPROACHES TO DEVELOP AN HIV VACCINE FAILED ? (0)
- Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105 (2009) (0)
- HIV-1 antibody 2F5 in complex with epitope scaffold ES2 (2010) (0)
- HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, T257S, V275C, S334A, S375W, A433M) Complexed with CD4 and Antibody 17b (2007) (0)
- Architecture of Mutualistic and Trophic Networks Stability of Ecological Communities and the (2010) (0)
- HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T123C, T257S, V275C,S334A, S375W, Q428C, G431C) Complexed with CD4 and Antibody 17b (2007) (0)
- Crystal structure of [Phe23]M47, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 GP120 envelope glycoprotein and anti-HIV-1 antibody 17B (2005) (0)
- Critical determinants in the emergence of broadly neutralizing CD4-binding site antibodies from an HIV-1-infected Chinese donor (2016) (0)
- Design clues from functional constraints and broadly neutralizing antibodies (2006) (0)
- HIV-1 gp120 Envelope Glycoprotein Complexed with the Broadly Neutralizing CD4-Binding-Site Antibody b12 (2007) (0)
- P09-13. Structure of HIV-1 gp41 interactive region: layered architecture and basis of conformational mobility (2009) (0)
- HIV-1 gp120 Envelope Glycoprotein (I109C, T257S, S334A, S375W, Q428C) Complexed with CD4 and Antibody 17b (2007) (0)
- Influence of Novel CD4 binding-defective HIV-1 Envelope Glycoprotein Immunogens on Neutralizing Antibody and T Cell Responses in Non- human Primates Running title: Novel CD4 binding-defective HIV-1 Env immunogens (2009) (0)
- 101 Chemokine Receptor CCR5 Mediates Resistance to West Nile Virus Infection in Mouse and Man (2009) (0)
- Structural basis of HIV-1 gp120 conformational mobility (2009) (0)
- Glycoprotein Immunization Plasma Cell Responses upon HIV-1 Envelope Independent Expansion of Epitope-Specific (2013) (0)
- Potent vaccine sera target epitopes that overlap the CD4 binding site. (2015) (0)
- Glycoproteins via CD 4 for Antigen Efficiently Capture HIV-1 Envelope Human Plasmacytoid Dendritic Cells (2013) (0)
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What Schools Are Affiliated With Richard T. Wyatt?
Richard T. Wyatt is affiliated with the following schools:
