Rikard Holmdahl
Swedish physician and immunologist
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Why Is Rikard Holmdahl Influential?
(Suggest an Edit or Addition)According to Wikipedia, Rikard Holmdahl is a Swedish physician and immunologist. He was appointed as a full professor and the head of Medical Inflammation Research unit at Lund University in 1993. In 2008, Rikard and his whole research group were recruited to Karolinska Institute. His team was the first to discover and positionally clone a single nucleotide polymorphism at the Ncf1 gene causing susceptibility to autoimmune diseases in rat models. Rikard was an adjunct member of the Nobel Committee for physiology or medicine between 2016 and 2021, and was ranked 2nd among the top immunology scientists in Sweden in 2021.
Rikard Holmdahl's Published Works
Published Works
- Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury (2008) (1215)
- Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines (2014) (667)
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (2019) (627)
- Positional identification of Ncf1 as a gene that regulates arthritis severity in rats (2003) (421)
- Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal anti-type II collagen antibodies. (1986) (379)
- Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene. (2004) (370)
- A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor (1999) (346)
- Type II Collagen Autoimmunity in Animals and Provocations Leading to Arthritis (1990) (315)
- Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes. (2003) (297)
- Progress and prospects in rat genetics: a community view (2008) (295)
- Macrophage migration inhibitory factor is involved in the pathogenesis of collagen type II-induced arthritis in mice. (1997) (260)
- Humoral immune response to citrullinated collagen type II determinants in early rheumatoid arthritis (2005) (253)
- Pristane-induced arthritis in rats: a new model for rheumatoid arthritis with a chronic disease course influenced by both major histocompatibility complex and non-major histocompatibility complex genes. (1996) (242)
- Estrogen induces a potent suppression of experimental autoimmune encephalomyelities and collagen-induced arthritis in mice (1994) (240)
- Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis (2009) (240)
- Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable. (2002) (235)
- Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease (2016) (235)
- T cell surface redox levels determine T cell reactivity and arthritis susceptibility (2006) (233)
- T Lymphocytes in Collagen II‐Induced Arthritis in Mice (1985) (233)
- Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species. (2007) (232)
- A putative vulnerability locus to multiple sclerosis maps to 5p14–p12 in a region syntenic to the murine locus Eae2 (1996) (231)
- Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients. (2010) (230)
- Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species (2010) (220)
- Genistein as an anti-inflammatory agent (2003) (219)
- The protective role of ROS in autoimmune disease. (2009) (217)
- Arthritis induced in rats with non‐immunogenic adjuvants as models for rheumatoid arthritis (2001) (216)
- Predominant selection of T cells specific for the glycosylated collagen type II epitope (263–270) in humanized transgenic mice and in rheumatoid arthritis (2002) (215)
- T cell recognition of carbohydrates on type II collagen (1994) (211)
- Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis (1995) (205)
- Homologous type II collagen induces chronic and progressive arthritis in mice. (1986) (202)
- Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles (2008) (200)
- Multiplex analyses of antibodies against citrullinated peptides in individuals prior to development of rheumatoid arthritis. (2013) (190)
- Expression of a transgenic class II Ab gene confers susceptibility to collagen‐induced arthritis (1994) (188)
- Genetic control of arthritis onset, severity and chronicity in a model for rheumatoid arthritis in rats (1998) (186)
- The molecular pathogenesis of collagen-induced arthritis in mice—a model for rheumatoid arthritis (2002) (183)
- Estrogen-mediated immunosuppression in autoimmune diseases (1998) (182)
- IFN-β Gene Deletion Leads to Augmented and Chronic Demyelinating Experimental Autoimmune Encephalomyelitis1 (2003) (181)
- NOX2 complex-derived ROS as immune regulators. (2011) (181)
- Epitope-specific recognition of type II collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen-induced arthritis in the mouse. (2002) (177)
- Combined sequence-based and genetic mapping analysis of complex traits in outbred rats (2013) (176)
- Epitope glycosylation plays a critical role for T cell recognition of type II collagen in collagen‐induced arthritis (1998) (175)
- Rheumatoid arthritis and the complement system (2007) (174)
- Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice. (1998) (172)
- Treatment with gamma-interferon triggers the onset of collagen arthritis in mice. (1988) (171)
- Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile (2012) (164)
- In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. (2009) (158)
- Oestrogen is a potent disease accelerator in SLE‐prone MRL lpr/lpr mice (1990) (157)
- A novel NOD-derived murine model of primary Sjögren's syndrome. (1998) (157)
- Adjuvant oils induce arthritis in the DA rat. I. Characterization of the disease and evidence for an immunological involvement (1991) (156)
- Estrogen accelerates immune complex glomerulonephritis but ameliorates T cell-mediated vasculitis and sialadenitis in autoimmune MRL lpr/lpr mice. (1992) (153)
- Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis (2007) (153)
- Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism (2015) (153)
- Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood (2016) (151)
- Identification of an immunodominant type‐II collagen peptide recognized by T cells in H‐2q mice: self tolerance at the level of determinant selection (1992) (150)
- Role of T lymphocytes in collagen II induced arthritis in rats. (1983) (148)
- A New Arthritis Therapy with Oxidative Burst Inducers (2006) (148)
- Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins (2013) (146)
- Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells (2004) (145)
- Arthritis in DBA/1 Mice Induced with Passively Transferred Type II Collagen Immune Serum (1990) (141)
- Induction of arthritis by single monoclonal IgG anti‐collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcγRIIB (2003) (141)
- Complement activation by both classical and alternative pathways is critical for the effector phase of arthritis (2004) (138)
- Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis. (2005) (136)
- The Th2 cytokines IL-4 and IL-10 are not crucial for the completion of allogeneic pregnancy in mice. (2001) (136)
- Homologous type II collagen-induced arthritis in rats. Characterization of the disease and demonstration of clinically distinct forms of arthritis in two strains of rats after immunization with the same collagen preparation. (1990) (136)
- Mucosal tolerance and suppression of collagen‐induced arthritis (CIA) induced by nasal inhalation of synthetic peptide 184‐198 of bovine type II collagen (CII) expressing a dominant T cell epitope (1996) (134)
- Female sex hormones suppress development of collagen-induced arthritis in mice. (1986) (133)
- Incidence of arthritis and autoreactivity of anti-collagen antibodies after immunization of DBA/1 mice with heterologous and autologous collagen II. (1985) (132)
- Evidence for Common Autoimmune Disease Genes Controlling Onset, Severity, and Chronicity Based on Experimental Models for Multiple Sclerosis and Rheumatoid Arthritis1 (2000) (130)
- Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies. (2007) (127)
- Analysis of type II collagen‐reactive T cells in the mouse I. Different regulation of autoreactive vs. non‐autoreactive anti‐type II collagen T cells in the DBA/1 mouse (1990) (123)
- Gamma-interferon-like immunoreactivity in axotomized rat motor neurons (1989) (123)
- Interleukin‐10 Suppresses the Development of Collagen Type II‐Induced Arthritis and Ameliorates Sustained Arthritis in Rats (1996) (120)
- Collagen antibody induced arthritis. (2007) (116)
- Autoimmune priming, tissue attack and chronic inflammation — The three stages of rheumatoid arthritis (2014) (115)
- A novel long noncoding RNA Lnc‐HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism (2016) (114)
- Mannan induces ROS-regulated, IL-17A–dependent psoriasis arthritis-like disease in mice (2014) (113)
- Collagen induced arthritis as an experimental model for rheumatoid arthritis (1989) (111)
- Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage (2015) (110)
- Endoglycosidase treatment abrogates IgG arthritogenicity: Importance of IgG glycosylation in arthritis (2007) (109)
- Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation (2016) (105)
- Immunogenetics of type II collagen autoimmunity and susceptibility to collagen arthritis. (1988) (105)
- Sialadenitis in the MRL-l mouse: morphological and immunohistochemical characterization of resident and infiltrating cells. (1987) (105)
- Genetic control of collagen‐induced arthritis in a cross with NOD and C57BL/10 mice is dependent on gene regions encoding complement factor 5 and FcγRIIb and is not associated with loci controlling diabetes (2001) (105)
- Collagen-induced arthritis development requires αβ T cells but not γδ T cells: studies with T cell-deficient (TCR mutant) mice (1999) (103)
- Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency. (2012) (103)
- Lack of Reactive Oxygen Species Breaks T Cell Tolerance to Collagen Type II and Allows Development of Arthritis in Mice1 (2007) (102)
- Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature. (2014) (101)
- Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise (2019) (101)
- Ethanol prevents development of destructive arthritis (2007) (101)
- Animal models for arthritis: innovative tools for prevention and treatment (2011) (100)
- Oestradiol- and testosterone-mediated effects on the immune system in normal and autoimmune mice are genetically linked and inherited as dominant traits. (1989) (100)
- The structural basis of MHC control of collagen‐induced arthritis; binding of the immunodominant type II collagen 256 – 270 glycopeptide to H‐2Aq and H‐2Ap molecules (1998) (100)
- Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps. (2017) (100)
- Arthritis-related B Cell Epitopes in Collagen II Are Conformation-dependent and Sterically Privileged in Accessible Sites of Cartilage Collagen Fibrils* (1998) (100)
- Early appearance of activated CD4+ T lymphocytes and class II antigen-expressing cells in joints of DBA/1 mice immunized with type II collagen. (1988) (100)
- Basal metabolic rate and the evolution of the adaptive immune system (2002) (99)
- Genetic linkage analysis of collagen‐induced arthritis in the mouse (1998) (98)
- Glycosylation of type II collagen is of major importance for T cell tolerance and pathology in collagen‐induced arthritis (2002) (95)
- Clonal expansion of T lymphocytes causes arthritis and mortality in mice infected with toxic shock syndrome toxin‐1‐producing staphylococci (1994) (95)
- Reactive Oxygen Species Produced by the NADPH Oxidase 2 Complex in Monocytes Protect Mice from Bacterial Infections (2012) (94)
- Antibodies to citrullinated proteins: molecular interactions and arthritogenicity (2010) (94)
- A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity (2007) (93)
- A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus (2017) (90)
- Systemic versus cartilage-specific expression of a type II collagen-specific T-cell epitope determines the level of tolerance and susceptibility to arthritis. (1996) (90)
- Genes on the X chromosome affect development of collagen‐induced arthritis in mice (1993) (89)
- Maintained pregnancy levels of oestrogen afford complete protection from post‐partum exacerbation of collagen‐induced arthritis (1991) (89)
- Genetic, hormonal and behavioural influence on spontaneously developing arthritis in normal mice (1992) (89)
- Pristane, a Non-Antigenic Adjuvant, Induces MHC Class II-Restricted, Arthritogenic T Cells in the Rat1 (2006) (88)
- A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock. (2009) (87)
- Identification of genes controlling collagen-induced arthritis in mice: striking homology with susceptibility loci previously identified in the rat. (1999) (86)
- NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence? (2017) (86)
- In Vivo Treatment of Rats with Monoclonal Anti‐T‐Cell Antibodies (1985) (86)
- A comparative analysis of B cell‐mediated myelin oligodendrocyte glycoprotein‐experimental autoimmune encephalomyelitis pathogenesis in B cell‐deficient mice reveals an effect on demyelination (2002) (85)
- The role of collagen antibodies in mediating arthritis (2008) (84)
- Screening of several H-2 congenic mouse strains identified H-2q mice as highly susceptible to MOG-induced EAE with minimal adjuvant requirement (2000) (83)
- Anti‐T cell receptor antibody treatment of rats with established autologous collagen‐induced arthritis: suppression of arthritis without reduction of anti‐type II collagen autoantibody levels (1991) (82)
- The occurrence of autoantibodies to matrilin 1 reflects a tissue-specific response to cartilage of the respiratory tract in patients with relapsing polychondritis. (2001) (81)
- A rapid and efficient immunization protocol for production of monoclonal antibodies reactive with autoantigens. (1985) (80)
- Interferon‐gamma‐like immunoreactivity in certain neurons of the central and peripheral nervous system (1989) (80)
- Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress. (2013) (80)
- Administration of Antibodies to Hyaluronanreceptor (CD44) Delays the Start and Ameliorates the Severity of Collagen II Arthritis (1995) (80)
- Validation of a multiplex chip-based assay for the detection of autoantibodies against citrullinated peptides (2012) (79)
- Role of T Lymphocytes in Experimental Staphylococcus aureus Arthritis (1994) (79)
- Monocyte- and Macrophage-Targeted NADPH Oxidase Mediates Antifungal Host Defense and Regulation of Acute Inflammation in Mice (2013) (78)
- The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritis. (2005) (78)
- The major T cell epitope on type II collagen is glycosylated in normal cartilage but modified by arthritis in both rats and humans (2005) (77)
- IL-10-Deficient B10.Q Mice Develop More Severe Collagen-Induced Arthritis, but Are Protected from Arthritis Induced with Anti-Type II Collagen Antibodies1 (2001) (77)
- Copy number variation of the gene NCF1 is associated with rheumatoid arthritis. (2012) (77)
- Autoantibodies to citrullinated proteins may induce joint pain independent of inflammation (2016) (77)
- Comment on "The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease" (2003) (76)
- Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases. (2001) (75)
- Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen (2005) (75)
- Blocking of experimental arthritis by cleavage of IgG antibodies in vivo. (2007) (75)
- Monoclonal antibodies with exclusive reactivity against parathyroid cells and tubule cells of the kidney. (1987) (74)
- The pineal hormone melatonin exaggerates development of collagen-induced arthritis in mice (1992) (74)
- Affinity binding of cells to cryogel adsorbents with immobilized specific ligands: effect of ligand coupling and matrix architecture (2005) (74)
- Macrophages, but not dendritic cells, present collagen to T cells (1995) (73)
- Integrated bioprocess for the production and isolation of urokinase from animal cell culture using supermacroporous cryogel matrices (2006) (72)
- Characterization of a spontaneously occurring arthritis in male DBA/1 mice. (1992) (72)
- Avridine-induced arthritis in rats; a T cell-dependent chronic disease influenced both by MHC genes and by non-MHC genes. (1995) (71)
- Antigen processing and presentation of a naturally glycosylated protein elicits major histocompatibility complex class II‐restricted, carbohydrate‐specific T cells (1996) (69)
- NADPH oxidase elevations in pyramidal neurons drive psychosocial stress-induced neuropathology (2012) (69)
- T Cells Recognize a Glycopeptide Derived from Type II Collagen in a Model for Rheumatoid Arthritis (1998) (69)
- Chronic experimental autoimmune encephalomyelitis induced by the 89‐101 myelin basic protein peptide in B10RIII (H2r) mice (1991) (69)
- Enhancement of collagen-induced arthritis in female mice by estrogen receptor blockage. (2001) (68)
- In vivo treatment with W3/13 (anti-pan T) but not with OX8 (anti-suppressor/cytotoxic T) monoclonal antibodies impedes the development of adjuvant arthritis in rats. (1985) (68)
- Treatment of experimental autoimmune arthritis by nasal administration of a type II collagen-cholera toxoid conjugate vaccine. (1999) (68)
- Therapeutic Vaccination of Active Arthritis with a Glycosylated Collagen Type II Peptide in Complex with MHC Class II Molecules1 (2006) (68)
- Mice with the xid B cell defect are less susceptible to developing Staphylococcus aureus-induced arthritis. (1995) (68)
- Clever-1/Stabilin-1 Controls Cancer Growth and Metastasis (2014) (67)
- Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat (2016) (66)
- Protective influences on experimental autoimmune encephalomyelitis by MHC class I and class II alleles. (1994) (66)
- Influence of CD4 or CD8 deficiency on collagen‐induced arthritis (2001) (64)
- The need for littermate controls (2012) (63)
- T lymphocytes are not required for the spontaneous development of entheseal ossification leading to marginal ankylosis in the DBA/1 mouse. (2000) (63)
- Mouse models for rheumatoid arthritis (2002) (63)
- The cathelicidins LL-37 and rCRAMP are associated with pathogenic events of arthritis in humans and rats (2012) (63)
- Increased serum levels of cartilage oligomeric matrix protein in chronic erosive arthritis in rats (1998) (62)
- Methotrexate ameliorates T cell dependent autoimmune arthritis and encephalomyelitis but not antibody induced or fibroblast induced arthritis (2004) (62)
- Immunopathological features of rat Staphylococcus aureus arthritis (1994) (62)
- Hyperinflammation of chronic granulomatous disease is abolished by NOX2 reconstitution in macrophages and dendritic cells (2012) (62)
- Reactivity of monoclonal anti-type II collagen antibodies with cartilage and synovial tissue in rheumatoid arthritis and osteoarthritis. (1986) (62)
- A new animal model for relapsing polychondritis, induced by cartilage matrix protein (matrilin-1). (1999) (61)
- Immunoglobulin-Secreting Cells of Maternal Origin Can Be Detected in B Cell-Deficient Mice1 (2000) (61)
- Neurodegeneration and glial activation patterns after mechanical nerve injury are differentially regulated by non‐MHC genes in congenic inbred rat strains (2001) (61)
- Oestrogen induced suppression of collagen arthritis. IV: Progesterone alone does not affect the course of arthritis but enhances the oestrogen-mediated therapeutic effect. (1989) (61)
- Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis (2016) (61)
- IL-10-Deficient B10.Q Mice Develop More Severe Collagen-Induced Arthritis, but Are Protected from Arthritis Induced with Anti-Type II Collagen Antibodies (2002) (59)
- T cells specific for post-translational modifications escape intrathymic tolerance induction (2018) (59)
- Arthritogenic antibodies specific for a major type II collagen triple-helical epitope bind and destabilize cartilage independent of inflammation. (2008) (59)
- Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats (2010) (58)
- Monoclonal anti-parathyroid antibodies interfering with a Ca2+-sensor of human parathyroid cells. (1987) (58)
- Host defense against cholera toxin is strongly CD4+ T cell dependent (1991) (58)
- How well do ACPA discriminate and predict RA in the general population: a study based on 12 590 population-representative Swedish twins (2016) (57)
- Identification of New Citrulline‐Specific Autoantibodies, Which Bind to Human Arthritic Cartilage, by Mass Spectrometric Analysis of Citrullinated Type II Collagen (2014) (57)
- Identification of epistasis through a partial advanced intercross reveals three arthritis loci within the Cia5 QTL in mice (2005) (57)
- Cyclosporin A treatment in a case of relapsing polychondritis. (1984) (56)
- Cartilage-binding antibodies induce pain through immune complex–mediated activation of neurons (2019) (55)
- Advanced Intercross Line Mapping of Eae5 Reveals Ncf-1 and CLDN4 as Candidate Genes for Experimental Autoimmune Encephalomyelitis1 (2006) (55)
- Enhanced XOR activity in eNOS-deficient mice: Effects on the nitrate-nitrite-NO pathway and ROS homeostasis. (2016) (55)
- CD1-Dependent Regulation of Chronic Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis 1 (2004) (54)
- The major histocompatibility complex influences myelin basic protein 63‐88‐induced T cell cytokine profile and experimental autoimmune encephalomyelitis (1993) (53)
- Complex genetic control in a rat model for rheumatoid arthritis. (2000) (53)
- IL‐4‐deficient mice develop less acute but more chronic relapsing collagen‐induced arthritis (2002) (53)
- Multifunctional T cell reactivity with native and glycosylated type II collagen in rheumatoid arthritis. (2012) (52)
- The Rheumatoid Arthritis-Associated Autoantigen hnRNP-A2 (RA33) Is a Major Stimulator of Autoimmunity in Rats with Pristane-Induced Arthritis1 (2007) (52)
- Analysis of Type II Collagen Reactive T Cells in the Mouse (1991) (52)
- Estrogen induced suppression of collagen arthritis. V: Physiological level of estrogen in DBA/1 mice is therapeutic on established arthritis, suppresses anti-type II collagen T-cell dependent immunity and stimulates polyclonal B-cell activity. (1990) (52)
- Genetics of susceptibility to chronic experimental encephalomyelitis and arthritis. (1998) (52)
- Novel Quantitative Trait Loci Controlling Development of Experimental Autoimmune Encephalomyelitis and Proportion of Lymphocyte Subpopulations1 (2003) (51)
- Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint (2014) (51)
- Structural Basis of Cross‐Reactivity of Anti–Citrullinated Protein Antibodies (2019) (51)
- Ia‐Expressing Cells and T Lymphocytes of Different Subsets in Peripheral Nerve Tissue during Experimental Allergic Neuritis in Lewis Rats (1983) (50)
- Collagen-induced arthritis development requires alpha beta T cells but not gamma delta T cells: studies with T cell-deficient (TCR mutant) mice. (1999) (50)
- Appearance of Different Lymphoid Cells in Synovial Tissue and in Peripheral Blood during the Course of Collagen II‐Induced Arthritis in Rats (1985) (50)
- Mice Lacking NCF1 Exhibit Reduced Growth of Implanted Melanoma and Carcinoma Tumors (2013) (50)
- Hydrogen peroxide as an immunological transmitter regulating autoreactive T cells. (2013) (50)
- Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice. (2005) (50)
- Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase (2005) (49)
- Structures on the I‐A molecule predisposing for susceptibility to type II collagen‐induced autoimmune arthritis (1990) (49)
- Dependence of SARS-CoV-2 infection on cholesterol-rich lipid raft and endosomal acidification (2021) (49)
- The B cell response to autologous type II collagen: biased V gene repertoire with V gene sharing and epitope shift. (1996) (49)
- The genetics of rheumatoid arthritis and the need for animal models to find and understand the underlying genes (2000) (49)
- Oestrogen is a potent immunomodulator of murine experimental rheumatoid disease. (1989) (49)
- Stromal cells and osteoclasts are responsible for exacerbated collagen-induced arthritis in interferon-beta-deficient mice. (2005) (49)
- Associations of antibodies against citrullinated peptides with human leukocyte antigen-shared epitope and smoking prior to the development of rheumatoid arthritis (2015) (48)
- Evaluation of the percentage of peripheral T cells with two different T cell receptor alpha-chains and of their potential role in autoimmunity. (2001) (48)
- High antibody response to autologous type II collagen is restricted to H-2q (2004) (48)
- Pathogenic IgG Antibodies against Desmoglein 3 in Pemphigus Vulgaris Are Regulated by HLA-DRB1*04:02–Restricted T Cells (2014) (48)
- Tracking of Proinflammatory Collagen-Specific T Cells in Early and Late Collagen-Induced Arthritis in Humanized Mice1 (2004) (47)
- Identification of a region in p47phox/NCF1 crucial for phagocytic NADPH oxidase (NOX2) activation (2013) (47)
- Placental MHC class I antigen expression is induced in mice following in vivo treatment with recombinant interferon-gamma. (1991) (47)
- Association of NOX2 subunits genetic variants with autoimmune diseases. (2018) (47)
- Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice (2014) (47)
- Homologous collagen‐induced arthritis in ratg and mice are associated with structurally different major histocompatibility complex DQ‐like molecules (1992) (46)
- Generation of Monoclonal Rheumatoid Factors after Immunization with Collagen II‐Anti‐Collagen II Immune Complexes (1986) (46)
- Association between protein tyrosine phosphatase 22 variant R620W in conjunction with the HLA-DRB1 shared epitope and humoral autoimmunity to an immunodominant epitope of cartilage-specific type II collagen in early rheumatoid arthritis. (2006) (46)
- In vivo elimination of T cells expressing specific T-cell receptor V beta chains in mice susceptible to collagen-induced arthritis. (1990) (45)
- New Loci Regulating Rat Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis1 (2003) (45)
- Role of gamma/delta T cell receptor‐expressing lymphocytes in cutaneous infection caused by Staphylococcus aureus (2003) (45)
- Copy number variation in autoimmunity — importance hidden in complexity? (2012) (44)
- Binding of autoreactive mouse anti-type II collagen antibodies derived from the primary and the secondary immune response investigated with the biosensor technique. (1995) (44)
- Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. (2017) (43)
- C57BL/6 mice need MHC class II Aq to develop collagen-induced arthritis dependent on autoreactive T cells (2012) (43)
- T-cell receptor V beta haplotype and complement component C5 play no significant role for the resistance to collagen-induced arthritis in the SWR mouse. (1991) (43)
- Are B Lymphocytes of Importance in Severe Staphylococcus aureus Infections? (2000) (43)
- Constant darkness enhances autoimmunity to type II collagen and exaggerates development of collagen-induced arthritis in DBA/1 mice (1990) (43)
- In vivo treatment with interferon-gamma during early pregnancy in mice induces strong expression of major histocompatibility complex class I and II molecules in uterus and decidua but not in extra-embryonic tissues. (1992) (43)
- Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways (2014) (43)
- Endogenous collagen peptide activation of CD1d-restricted NKT cells ameliorates tissue-specific inflammation in mice. (2011) (43)
- Autoimmune recognition of cartilage collagens. (1993) (42)
- Transgenic mouse models of rheumatoid arthritis (1999) (42)
- Relapsing polychondritis, induced in mice with matrilin 1, is an antibody- and complement-dependent disease. (2004) (42)
- Arthritis is associated with T-cell-induced upregulation of Toll-like receptor 3 on synovial fibroblasts (2011) (42)
- Role of glycopeptide-specific T cells in collagen-induced arthritis: an example how Dost-translational modification of proteins Gay be involved in autoimmune disease (2001) (41)
- Pregnancy in B-cell-deficient mice: postpartum transfer of immunoglobulins prevents neonatal runting and death. (1994) (41)
- Immunization of rats with homologous type XI collagen leads to chronic and relapsing arthritis with different genetics and joint pathology than arthritis induced with homologous type II collagen. (2002) (41)
- Dynamics of Ia-expressing cells and T lymphocytes of different subsets during experimental allergic neuritis in Lewis rats (1984) (41)
- The mtDNA nt7778 G/T polymorphism affects autoimmune diseases and reproductive performance in the mouse. (2009) (40)
- Anticitrullinated protein/peptide antibody multiplexing defines an extended group of ACPA-positive rheumatoid arthritis patients with distinct genetic and environmental determinants (2017) (40)
- Germline‐Encoded IgG Antibodies Bind Mouse Cartilage In Vivo: Epitope‐ and Idiotype‐Specific Binding and Inhibition (1994) (40)
- Genetic Interactions in Eae2 Control Collagen-Induced Arthritis and the CD4+/CD8+ T Cell Ratio1 (2005) (40)
- The structure, specificity and function of anti-citrullinated protein antibodies (2019) (40)
- Immunohistochemical characterization of synovial cells in arthritic MRL-lpr/lpr mice. (1987) (40)
- Arthritogenic anti-type II collagen antibodies are pathogenic for cartilage-derived chondrocytes independent of inflammatory cells. (2005) (39)
- Female Preponderance for Development of Arthritis in Rats is Influenced by both Sex Chromosomes and Sex Steroids (1995) (39)
- Control of parasitemia and survival during Trypanosoma brucei brucei infection is related to strain-dependent ability to produce IL-4. (1996) (39)
- Adaptations to high-intensity interval training in skeletal muscle require NADPH oxidase 2 (2019) (39)
- Major histocompatibility complex‐controlled protective influences on experimental autoimmune encephalomyelitis are peptide specific (1997) (39)
- Pinealectomy ameliorates collagen II‐induced arthritis in mice (1993) (39)
- Arthritis induced with cartilage‐specific antibodiesis IL‐4‐dependent (2006) (39)
- Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice (2006) (39)
- Cartilage‐specific autoimmunity in rheumatoid arthritis: characterization of a triple helical B cell epitope in the integrin‐binding‐domain of collagen type II (2001) (38)
- A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis (2010) (38)
- The genetic control of rheumatoid factor production in a rat model of rheumatoid arthritis. (2003) (38)
- Spreading of the immune response to different myelin basic protein peptides in chronic experimental autoimmune encephalomyelitis in B10.RIII mice (1995) (38)
- Approach for Identifying Human Leukocyte Antigen (HLA)-DR Bound Peptides from Scarce Clinical Samples * (2016) (38)
- Cell death and cytokine production induced by autoimmunogenic hydrocarbon oils (2012) (38)
- High expression of liver histone deacetylase 3 contributes to high-fat-diet-induced metabolic syndrome by suppressing the PPAR-γ and LXR-α-pathways in E3 rats (2011) (38)
- Genetic links between the acute‐phase response and arthritis development in rats (2002) (37)
- Origin of the autoreactive anti-type II collagen response. I. Frequency of specific and multispecific B cells in primed murine lymph nodes. (1987) (37)
- Down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2 in nonalcoholic steatohepatitis of high-fat-diet-induced metabolic syndrome E3 rats (2015) (37)
- The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis (2009) (37)
- Identification and Isolation of Dominant Susceptibility Loci for Pristane-Induced Arthritis1 (2003) (37)
- Enhancement of DTH reaction and inhibition of the expression of class II transplantation antigens by in vivo treatment with antibodies against gamma-interferon. (1988) (36)
- C4b-binding protein (C4BP) inhibits development of experimental arthritis in mice (2008) (36)
- Allelic variations in rat MHC class II binding of myelin basic protein peptides correlate with encephalitogenicity. (1999) (35)
- Monoclonal Antibody Production Using a New Supermacroporous Cryogel Bioreactor (2007) (35)
- A Novel HLA–DRB1*10:01–Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis (2015) (35)
- Chronicity of Tissue‐Specific Experimental Autoimmune Disease: A Role for B Cells? (1995) (35)
- Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro (2005) (34)
- Variable region gene selection of immunoglobulin G‐expressing B cells with specificity for a defined epitope on type II collagen (1993) (34)
- In vivo treatment of rats with monoclonal antibodies against gamma interferon: effects on experimental allergic neuritis (1989) (34)
- Chronicity of arthritis induced with homologous type II collagen (CII) in rats is associated with anti-CII B-cell activation. (1994) (34)
- Positioning of a polymorphic quantitative trait nucleotide in the Ncf1 gene controlling oxidative burst response and arthritis severity in rats. (2011) (34)
- T cells that are naturally tolerant to cartilage-derived type II collagen are involved in the development of collagen-induced arthritis (2000) (33)
- Citrullination of collagen II affects integrin‐mediated cell adhesion in a receptor‐specific manner (2014) (33)
- Antileukoproteinase: modulation of neutrophil function and therapeutic effects on anti-type II collagen antibody-induced arthritis. (2004) (33)
- Genetic Control of Tolerance to Type II Collagen and Development of Arthritis in an Autologous Collagen-Induced Arthritis Model 1 (2003) (33)
- Epitope-specific antibody response is controlled by immunoglobulin VH polymorphisms (2014) (33)
- The impact of glycosylation on HLA-DR1-restricted T cell recognition of type II collagen in a mouse model. (2006) (33)
- Rheumatoid arthritis: identifying and characterising polymorphisms using rat models (2016) (32)
- Crystal structure of an arthritogenic anticollagen immune complex. (2011) (32)
- A comparative genetic analysis between collagen‐induced arthritis and pristane‐induced arthritis (2003) (32)
- Identification of a major antigenic epitope on CNBr‐fragment 11 of type II collagen recognized by murine autoreactive B cells (1991) (31)
- Presence of autoantibodies in “seronegative” rheumatoid arthritis associates with classical risk factors and high disease activity (2020) (31)
- Glycopeptide Specificity of Helper T Cells Obtained in Mouse Models for Rheumatoid Arthritis (2002) (31)
- Decreased neuropeptide-converting enzyme activities in cerebrospinal fluid during acute but not chronic phases of collagen induced arthritis in rats (1992) (31)
- Analysis of the genetic encoding of oestradiol suppression of delayed-type hypersensitivity in (NZB x NZW) F1 mice. (1991) (31)
- Ncf1-Associated Reduced Oxidative Burst Promotes IL-33R+ T Cell-Mediated Adjuvant-Free Arthritis in Mice12 (2009) (31)
- Enhancement of antibody-induced arthritis via Toll-like receptor 2 stimulation is regulated by granulocyte reactive oxygen species. (2012) (31)
- Oestradiol suppression of delayed-type hypersensitivity in autoimmune (NZB/NZW)F1 mice is a trait inherited from the healthy NZW parental strain. (1989) (31)
- Cartilage oligomeric matrix protein induction of chronic arthritis in mice. (2008) (31)
- Genetic influence on disease course and cytokine response in relapsing experimental allergic encephalomyelitis. (1998) (30)
- Polymeric cryogels are biocompatible, and their biodegradation is independent of oxidative radicals. (2014) (30)
- Backcross and Partial Advanced Intercross Analysis of Nonobese Diabetic Gene-Mediated Effects on Collagen-Induced Arthritis Reveals an Interactive Effect by Two Major Loci1 (2006) (30)
- Linomide, a new immunomodulatory drug, shows different effects on homologous versus heterologous collagen-induced arthritis in rats. (1989) (30)
- Cartilage-specific autoimmunity in animal models and clinical aspects in patients – focus on relapsing polychondritis (2002) (30)
- Different therapeutic and bystander effects by intranasal administration of homologous type II and type IX collagens on the collagen-induced arthritis and pristane-induced arthritis in rats. (1999) (29)
- CD68‐expressing cells can prime T cells and initiate autoimmune arthritis in the absence of reactive oxygen species (2011) (29)
- Oestrogen‐induced suppression of collagen arthritis; 17β‐oestradiol is therapeutically active in normal and castrated F1 hybrid mice of both sexes (1992) (29)
- Advanced Intercross Line Mapping Suggests That Ncf1 (Ean6) Regulates Severity in an Animal Model of Guillain-Barré Syndrome1 (2009) (28)
- Transgenic mice expressing human FcgammaRIIa have enhanced sensitivity to induced autoimmune arthritis as well as elevated Th17 cells. (2010) (28)
- Deficient Production of Reactive Oxygen Species Leads to Severe Chronic DSS-Induced Colitis in Ncf1/p47phox-Mutant Mice (2014) (28)
- Germinal Center B Cells Are Essential for Collagen‐Induced Arthritis (2018) (28)
- Contrasting roles of plasminogen deficiency in different rheumatoid arthritis models. (2005) (28)
- Dissection of the genetic complexity of arthritis using animal models. (2003) (28)
- No role of interleukin‐4 in CD23/IgE‐mediated enhancement of the murine antibody response in vivo (1995) (28)
- Genetic Heterogeneity of Autoimmune Disorders in the Nonobese Diabetic Mouse (2003) (28)
- Arthritis suppression by NADPH activation operates through an interferon-β pathway (2007) (28)
- Both common and unique susceptibility genes in different rat strains with pristane-induced arthritis (2002) (27)
- Pristane-induced arthritis in the rat. (2007) (27)
- NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus (2019) (27)
- Identification of susceptibility genes for experimental autoimmune encephalomyelitis that overcome the effect of protective alleles at the eae2 locus. (2002) (27)
- A genetic linkage map of the rat (1999) (26)
- Do “infectious” prey select for high levels of natural antibodies in tropical pythons? (2007) (26)
- Estrogen-induced suppression of collagen arthritis III. Adult thymectomy does not affect the course of arthritis or the estrogen-mediated suppression of T-cell immunity (1988) (26)
- Bacillus Calmette-Guerin Infection in NADPH Oxidase Deficiency: Defective Mycobacterial Sequestration and Granuloma Formation (2014) (26)
- Mannan-induced Nos2 in macrophages enhances IL-17–driven psoriatic arthritis by innate lymphocytes (2018) (26)
- Identification of conformation-dependent epitopes and V gene selection in the B cell response to type II collagen in the DA rat. (2001) (26)
- Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis (2014) (26)
- ‘SMASH’ recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models (2021) (26)
- Association of Pepsin with Type II Collagen (CII) Breaks Control of CII Autoimmunity and Triggers Development of Arthritis in Rats (1993) (25)
- Role of T lymphocytes in murine collagen induced arthritis (1986) (25)
- SAT0065 Acpa against different citrullinated peptides identify specific phenotypes of rheumatoid arthritis (2017) (25)
- The Macrophage Mannose Receptor Regulate Mannan-Induced Psoriasis, Psoriatic Arthritis, and Rheumatoid Arthritis-Like Disease Models (2018) (25)
- Genomes and phenomes of a population of outbred rats and its progenitors (2014) (25)
- Modulation of experimental allergic neuritis in rats by in vivo treatment with monoclonal anti T cell antibodies (1988) (25)
- Cellular heterogeneity in cultured human chondrocytes identified by antibodies specific for alpha 2(XI) collagen chains (1989) (24)
- Chronicity of pristane-induced arthritis in rats is controlled by genes on chromosome 14. (2003) (24)
- Type II collagen in cartilage evokes peptide-specific tolerance and skews the immune response. (1998) (24)
- High-resolution mapping of a complex disease, a model for rheumatoid arthritis, using heterogeneous stock mice. (2011) (24)
- Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis (2008) (24)
- Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis. (2019) (23)
- Tolerance induction using lentiviral gene delivery delays onset and severity of collagen II arthritis. (2009) (23)
- The genetic control of sialadenitis versus arthritis in a NOD.Q×B10.Q F2 cross (2002) (23)
- Phytol: A Chlorophyll Component with Anti-inflammatory and Metabolic Properties (2014) (23)
- Dominant suppression of inflammation by glycan-hydrolyzed IgG (2013) (23)
- Cell-specific and efficient expression in mouse and human B cells by a novel hybrid immunoglobulin promoter in a lentiviral vector (2007) (23)
- Three‐dimensional culture for monoclonal antibody production by hybridoma cells immobilized in macroporous gel particles (2008) (23)
- Positional Identification of RT1-B (HLA-DQ) as Susceptibility Locus for Autoimmune Arthritis (2015) (23)
- Oestrogen‐Mediated Suppression of Collagen‐Induced Arthritis in Rats (1989) (22)
- Synthesis of a C‐Glycoside Analogue of β‐D‐Galactosyl Hydroxynorvaline and Its Use in Immunological Studies (2000) (22)
- Depletion of murine T cells by in vivo monoclonal antibody treatment is enhanced by adding an autologous anti-rat kappa chain antibody. (1988) (22)
- Increased levels of prolactin during, but not after, the immunisation with rat collagen II enhances the course of arthritis in DBA/1 mice. (1992) (22)
- Low Production of Reactive Oxygen Species Drives Systemic Lupus Erythematosus. (2019) (22)
- Activation and selection of NK cells via recognition of an allogeneic, non‐classical MHC class I molecule, RT1‐E (1999) (22)
- A 9-Centimorgan Interval of Chromosome 10 Controls the T Cell-Dependent Psoriasiform Skin Disease and Arthritis in a Murine Psoriasis Model1 (2008) (22)
- Therapeutic cleavage of IgG: new avenues for treating inflammation. (2008) (22)
- Type II collagen-specific antibodies induce cartilage damage in mice independent of inflammation. (2013) (22)
- Positional cloning of the Igl genes controlling rheumatoid factor production and allergic bronchitis in rats (2008) (22)
- The Y chromosome‐linked “autoimmune accelerating” yaa gene suppresses collagen‐induced arthritis (1994) (22)
- An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting (2015) (22)
- A Single Functional Group Substitution in C5a Breaks B Cell and T Cell Tolerance and Protects Against Experimental Arthritis (2014) (21)
- Class II major histocompatibility complex-associated response to type XI collagen regulates the development of chronic arthritis in rats. (2012) (21)
- In Vivo Imaging of Reactive Oxygen and Nitrogen Species in Murine Colitis (2014) (21)
- Pathogenic Autoreactive B Cells Are Not Negatively Selected toward Matrix Protein Collagen II (2011) (21)
- T cell response of I-Aq mice to self type II collagen: meshing of the binding motif of the I-Aq molecule with repetitive sequences results in autoreactivity to multiple epitopes. (1997) (21)
- Influence on Spontaneous Tissue Inflammation by the Major Histocompatibility Complex Region in the Nonobese Diabetic Mouse (2005) (20)
- Genetic control of antibody production during collagen induced arthritis development in heterogeneous stock mice (2012) (20)
- Oxazole-modified glycopeptides that target arthritis-associated class II MHC A(q) and DR4 proteins. (2010) (20)
- Pharmacological Potential of NOX2 Agonists in Inflammatory Conditions. (2015) (20)
- Connection between autoimmunity to cartilage type II collagen and rheumatoid factor production. (1987) (20)
- Cartilage oligomeric matrix protein specific antibodies are pathogenic (2012) (20)
- Identification of Genetic Regions of Importance for Reproductive Performance in Female Mice (2006) (20)
- Fragmentation of Two Quantitative Trait Loci Controlling Collagen-Induced Arthritis Reveals a New Set of Interacting Subloci1 (2007) (20)
- Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms. (2017) (20)
- CTLA‐4 expressed by FOXP3+ regulatory T cells prevents inflammatory tissue attack and not T‐cell priming in arthritis (2017) (20)
- Pristane primed rat T cells enhance TLR3 expression of fibroblast-like synoviocytes via TNF-α initiated p38 MAPK and NF-κB pathways. (2015) (20)
- Specific antibody protection of the extracellular cartilage matrix against collagen antibody-induced damage. (2010) (20)
- Amelioration of type II collagen induced arthritis in rats by treatment with sodium diethyldithiocarbamate. (1999) (20)
- Rabeximod reduces arthritis severity in mice by decreasing activation of inflammatory cells (2010) (19)
- Demonstration of immunoreactive sites on cartilage after in vivo administration of biotinylated anti-type II collagen antibodies. (1989) (19)
- Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity (2006) (19)
- A glucose-6-phosphate isomerase peptide induces T and B cell-dependent chronic arthritis in C57BL/10 mice: arthritis without reactive oxygen species and complement. (2013) (19)
- Antibody binding to a collagen type‐II epitope gives rise to an inhibitory peptide for autoreactive T cells (1992) (19)
- TNF Production in Macrophages Is Genetically Determined and Regulates Inflammatory Disease in Rats (2010) (18)
- Ncf1 Provides a Reactive Oxygen Species-Independent Negative Feedback Regulation of TLR9-Induced IL-12p70 in Murine Dendritic Cells1 (2009) (18)
- Probing molecular interactions within class II MHC Aq/glycopeptide/T-cell receptor complexes associated with collagen-induced arthritis. (2007) (18)
- Bb2Bb3 regulation of murine Lyme arthritis is distinct from Ncf1 and independent of the phagocyte nicotinamide adenine dinucleotide phosphate oxidase. (2005) (18)
- Natural Polymorphisms in Tap2 Influence Negative Selection and CD4∶CD8 Lineage Commitment in the Rat (2014) (18)
- Association of MHC and rheumatoid arthritis: Why is rheumatoid arthritis associated with the MHC genetic region? An introduction (2000) (18)
- Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats (2003) (18)
- The major histocompatibility complex influences myelin basic protein 63–88 induced T cell cytokine profile and experimental autoimmune encephalomyelitis (1994) (18)
- Positional Cloning of Ncf1– a Piece in the Puzzle of Arthritis Genetics (2003) (18)
- Therapeutic Effects of Monoclonal Antibodies to αβTCR but Not to CD4 on Collagen-Induced Arthritis in the Rat (1994) (17)
- Emerging glyco‐based strategies to steer immune responses (2021) (17)
- A genetic contamination in MHC‐congenic mouse strains reveals a locus on chromosome 10 that determines autoimmunity and arthritis susceptibility (2005) (17)
- Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development (2011) (17)
- A Restricted Role for FcγR in the Regulation of Adaptive Immunity (2018) (17)
- Effects of sialadenitis after cellular transfer in autoimmune MRL/lpr mice. (1997) (17)
- An investigation of allogeneic pregnancy in multiparous mice subjected to in vivo depletion of CD8 (Ly2)-positive lymphocytes by monoclonal antibody treatment. (1988) (17)
- Activated type II collagen reactive T cells are not eliminated by in vivo anti-CD4 treatment. Implications for therapeutic approaches on autoimmune arthritis. (1992) (17)
- Maternal Antibodies Protect Immunoglobulin Deficient Neonatal Mice From Mouse Hepatitis Virus (MHV)‐Associated Wasting Syndrome (1996) (17)
- Recent advances on smart glycoconjugate vaccines in infections and cancer (2021) (17)
- Identification of the minimal glycopeptide core recognized by T cells in a model for rheumatoid arthritis. (2005) (17)
- Analysis of autoreactive T cells associated with murine collagen-induced arthritis using peptide-MHC multimers. (2004) (17)
- System A amino acid transporters regulate glutamine uptake and attenuate antibody‐mediated arthritis (2015) (17)
- MHC class II alleles associated with Th1 rather than Th17 type immunity drive the onset of early arthritis in a rat model of rheumatoid arthritis (2017) (17)
- Patterns of autoreactivity to collagen type II in autoimmune MRL/l mice. (1986) (17)
- Modulation of granulocyte-endothelium interactions by antileukoproteinase: inhibition of anti-type II collagen antibody-induced leukocyte attachment to the synovial endothelium (2006) (17)
- Infiltrating mononuclear cells in salivary glands and kidneys in autoimmune MRL/Mp-lpr/lpr mice express IL-2 receptor and produce interferon-gamma. (1990) (17)
- Germ‐free mice deficient of reactive oxygen species have increased arthritis susceptibility (2015) (16)
- Extra‐articular cartilage affected in collagen‐induced, but not pristane‐induced, arthritis models (2002) (16)
- Design of Glycopeptides Used to Investigate Class II MHC Binding and T-Cell Responses Associated with Autoimmune Arthritis (2011) (16)
- A monoclonal antibody-based immunodiagnostic assay for onchocerciasis. (1992) (16)
- A retroviral gp70-related protein is expressed at specific stages during mouse oocyte maturation and in preimplantation embryos. (1989) (16)
- Cutting Edge: Processing of Oxidized Peptides in Macrophages Regulates T Cell Activation and Development of Autoimmune Arthritis (2017) (16)
- Inconsistent susceptibility to autoimmunity in inbred LEW rats is due to genetic crossbreeding involving segregation of the arthritis-regulating gene Ncf1. (2004) (16)
- Different populations of rheumatoid adherent cells mediate activation versus suppression of T lymphocyte proliferation. (1985) (16)
- Two-loci interaction confirms arthritis-regulating quantitative trait locus on rat chromosome 6. (2003) (16)
- Identification of collagen-induced arthritis loci in aged multiparous female mice (2006) (15)
- Major Histocompatibility Complex Class II Region Confers Susceptibility to Staphylococcus aureus Arthritis (1997) (15)
- Role of the galactosyl moiety of collagen glycopeptides for T-cell stimulation in a model for rheumatoid arthritis. (2003) (15)
- Chemical changes demonstrated in cartilage by synchrotron infrared microspectroscopy in an antibody-induced murine model of rheumatoid arthritis. (2011) (15)
- Oestrogen-induced suppression of collagen arthritis. II. Treatment of rats suppresses development of arthritis but does not affect the anti-type II collagen humoral response. (1987) (15)
- Collagen type II is recognized by a pathogenic antibody through germline encoded structures (2008) (15)
- Finemapping of the arthritis QTL Pia7 reveals co-localization with Oia2 and the APLEC locus (2010) (15)
- Conserved 33-kb haplotype in the MHC class III region regulates chronic arthritis (2016) (15)
- The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice (2007) (15)
- (E)-alkene and ethylene isosteres substantially alter the hydrogen-bonding network in class II MHC A(q)/glycopeptide complexes and affect T-cell recognition. (2011) (14)
- Natural polymorphism of Ym1 regulates pneumonitis through alternative activation of macrophages (2020) (14)
- Effects of oestradiol and raloxifene on the induction and effector phases of experimental postmenopausal arthritis and secondary osteoporosis (2011) (14)
- Pristane induces autophagy in macrophages, promoting a STAT1-IRF1-TLR3 pathway and arthritis. (2017) (14)
- A Transient Post-Translationally Modified Form of Cartilage Type II Collagen Is Ignored by Self-Reactive T Cells1 (2004) (14)
- Antigen-Specific Gene Therapy after Immunisation Reduces the Severity of Collagen-Induced Arthritis (2013) (14)
- Primed B Cells Present Type‐II Collagen to T Cells (2002) (14)
- The autoantibody response to cyclic citrullinated collagen type II peptides in rheumatoid arthritis. (2019) (14)
- Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949. (2019) (14)
- Antibodies against citrullinated peptides are associated with clinical and radiological outcomes in patients with early rheumatoid arthritis: a prospective longitudinal inception cohort study (2019) (14)
- Gene expression profiling of arthritis using a QTL chip reveals a complex gene regulation of the Cia5 region in mice (2005) (14)
- The novel small molecule drug Rabeximod is effective in reducing disease severity of mouse models of autoimmune disorders (2008) (13)
- VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis (2017) (13)
- Limited polymorphism in the first domain of the rat MHC class II RT1-D molecule (1998) (13)
- Oligoclonality of T cells in salivary glands of autoimmune MRL/lpr mice. (1994) (13)
- Protective role of sialophorin (CD43)-expressing cells in experimental Staphylococcus aureus infection (1994) (13)
- Effects by periodontitis on pristane-induced arthritis in rats (2016) (13)
- Perforin deficiency attenuates collagen-induced arthritis (2005) (13)
- Anti–Citrullinated Protein Antibody Specificities, Rheumatoid Factor Isotypes, and Incident Cardiovascular Events in Patients With Rheumatoid Arthritis (2020) (13)
- The crystal structure of the pathogenic collagen type II-specific mouse monoclonal antibody CIIC1 Fab: structure to function analysis. (2008) (13)
- The involvement of Toll‐like receptor 9 in the pathogenesis of erosive autoimmune arthritis (2018) (13)
- Tryptophan catabolism is unaffected in chronic granulomatous disease (2014) (13)
- Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis (2020) (13)
- Total abrogation of collagen II-induced arthritis and the B cell response to type II collagen using suboptimal doses of a topoisomerase II antagonist (2002) (13)
- Critical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in mice (2004) (13)
- NOX2 mediates quiescent handling of dead cell remnants in phagocytes (2019) (13)
- Reactive Oxygen Species in Psoriasis and Psoriasis Arthritis: Relevance to Human Disease (2015) (12)
- Regulation of T Cell Function by Reactive Nitrogen and Oxygen Species in Collagen-Induced Arthritis. (2020) (12)
- Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis (2016) (12)
- Tissue transglutaminase enhances collagen type II‐induced arthritis and modifies the immunodominant T‐cell epitope CII260‐270 (2009) (12)
- Pineal gland in autoimmunity: melatonin-dependent exaggeration of collagen-induced arthritis in mice. (1994) (12)
- A monoclonal antiidiotypic antibody with rheumatoid factor activity defines a cross-reactive idiotope on murine anticollagen antibodies. (1991) (12)
- Role of endogenous and exogenous female sex hormones in arthritis and osteoporosis development in B10.Q-ncf1*/* mice with collagen-induced chronic arthritis (2010) (12)
- Identification of Susceptibility Loci for Skin Disease in a Murine Psoriasis Model1 (2006) (12)
- Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes (2015) (12)
- Immunoregulation in arthritis. A review on synovial immune reactions in RA and in some experimental animal models for arthritis. (1987) (12)
- Chronic Active Arthritis Driven by Macrophages Without Involvement of T Cells (2018) (12)
- Interactions of mammalian cells with collagen. (1984) (12)
- Down-regulation of collagen arthritis after in vivo treatment with a syngeneic monoclonal anti-idiotypic antibody to a cross-reactive idiotope on collagen II auto-antibodies. (1991) (12)
- Characterization of chemically defined poly-N-isopropylacrylamide based copolymeric adjuvants. (2013) (11)
- Streptococcal Endo-β-N-Acetylglucosaminidase Suppresses Antibody-Mediated Inflammation In Vivo (2018) (11)
- Side-chain and backbone amide bond requirements for glycopeptide stimulation of T-cells obtained in a mouse model for rheumatoid arthritis. (2006) (11)
- Quantitative structure-activity relationship of peptides binding to the class II major histocompatibility complex molecule Aq associated with autoimmune arthritis. (2007) (11)
- Combined proinflammatory cytokine and cognate activation of invariant natural killer T cells enhances anti-DNA antibody responses (2020) (11)
- Cysteine proteases in Langerhans cells limits presentation of cartilage derived type II collagen for autoreactive T cells. (2004) (11)
- Collagen type II and a thermo-responsive polymer of N-isopropylacrylamide induce arthritis independent of Toll-like receptors: a strong influence by major histocompatibility complex class II and Ncf1 genes. (2011) (11)
- Identification of candidate risk gene variations by whole-genome sequence analysis of four rat strains commonly used in inflammation research (2014) (11)
- Two monoclonal antibodies to precisely the same epitope of type II collagen select non-crossreactive phage clones by phage display: implications for autoimmunity and molecular mimicry. (2004) (11)
- Detection of arthritis-susceptibility loci, including Ncf1, and variable effects of the major histocompatibility complex region depending on genetic background in rats. (2009) (11)
- A molecule basis for the HLA association in rheumatoid arthritis. (2000) (11)
- Genetics of autoimmune diseases: a multistep process. (2006) (10)
- B‐cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production (2015) (10)
- Intrinsic Tolerance in Autologous Collagen-Induced Arthritis Is Generated by CD152-Dependent CD4+ Suppressor Cells1 (2005) (10)
- Neutrophil-derived reactive oxygen species promote tumor colonization (2021) (10)
- Dissection of the genetic complexity of arthritis using animal models. (2006) (10)
- 17β‐Estradiol Expands IgA‐Producing B Cells in Mice Deficient for the μ Chain (2007) (10)
- In vivo treatment with anti‐CD8 and anti‐CD5 monoclonal antibodies alters induced tolerance to adjuvant arthritis (1989) (10)
- Rheumatoid factors in mice. (1989) (10)
- T cell responses to a non-glycosylated epitope predominate in type II collagen-immunised HLA-DRB1*0101 transgenic mice (2006) (10)
- Binding of Collagen Type II to Rheumatoid Synovial Cells (1986) (10)
- The H2-Ab gene influences the severity of experimental allergic encephalomyelitis induced by proteolipoprotein peptide 103–116 (2001) (10)
- Dissection of a locus on mouse chromosome 5 reveals arthritis promoting and inhibitory genes (2009) (10)
- A dominant suppressive MHC class II haplotype interacting with autosomal genes controls autoantibody production and chronicity of arthritis (2011) (10)
- Rheumatoid arthritis viewed using a headache paradigm (2000) (10)
- (18)F-Labeling of Mannan for Inflammation Research with Positron Emission Tomography. (2016) (10)
- Arthritis Susceptibility in Mice Expressing Human Type II Collagen in Cartilage (1997) (10)
- Type II collagen without adjuvant induces eosinophilic arthritis (2007) (10)
- Regulation by T cells of delayed hypersensitivity reaction in mouse lung as reflected by mononuclear cells, mast cells and mucus-producing cells. (1988) (9)
- In vivo monoclonal antibody treatment with Ox19 (anti-rat CD5) causes disease relapse and terminates P2-induced immunospecific tolerance in experimental allergic neuritis (1989) (9)
- Reversal of tolerance induced by transplantation of skin expressing the immunodominant T cell epitope of rat type II collagen entitles development of collagen‐induced arthritis but not graft rejection (2002) (9)
- Methylcholanthrene-Induced Sarcomas Develop Independently from NOX2-Derived ROS (2015) (9)
- The SKG Mutation in ZAP‐70 also Confers Arthritis Susceptibility in C57 Black Mouse Strains (2016) (9)
- Macrophage‐derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant (2016) (9)
- Differences in the Spectrum of Anti–Citrullinated Protein Antibody Fine Specificities Between Malaysian and Swedish Patients With Rheumatoid Arthritis: Implications for Disease Pathogenesis (2016) (9)
- Maintained allogeneic pregnancy in rats depleted of T cytotoxic/suppressor cells by OX8 monoclonal antibody treatment. (1987) (9)
- Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation (2022) (9)
- Superoxide Dismutase 3 Limits Collagen-Induced Arthritis in the Absence of Phagocyte Oxidative Burst (2012) (9)
- Characterization of the anticollagen antibody response in a new model of chronic polyarthritis. (2011) (9)
- Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949 (2019) (9)
- Mice Producing Less Reactive Oxygen Species Are Relatively Resistant to Collagen Glycopeptide Vaccination against Arthritis (2010) (9)
- Effects of Monoclonal Anti‐T Cell Antibodies on Rat Cardiac Allografts (1987) (8)
- Nerve conduction velocity is regulated by the inositol polyphosphate-4-phosphatase II gene. (2014) (8)
- Comparative analysis of collagen type II-specific immune responses during development of collagen-induced arthritis in two B10 mouse strains (2012) (8)
- DA rats from two colonies differ genetically and in their arthritis susceptibility (2008) (8)
- Vitamin D3 receptor polymorphisms regulate T cells and T cell-dependent inflammatory diseases (2020) (8)
- Genomes and phenomes of a population of outbred rats and its progenitors (2014) (8)
- A Shared Epitope of Collagen Type XI and Type II Is Recognized by Pathogenic Antibodies in Mice and Humans with Arthritis (2018) (8)
- Oligoclonal IgG bands synthesized in the central nervous system are present in rats with experimental autoimmune encephalomyelitis (2004) (8)
- Human α-enolase is immunogenic, but not arthritogenic, in HLA-DR4-transgenic mice: comment on the article by Kinloch et al. (2012) (8)
- Increased susceptibility to collagen-induced arthritis in female mice carrying congenic Cia40/Pregq2 fragments (2008) (8)
- Reactive Oxygen Species Regulate Innate But Not Adaptive Inflammation in ZAP70-Mutated SKG Arthritic Mice. (2016) (8)
- Self-reactive T cells induce and perpetuate chronic relapsing arthritis (2020) (8)
- A Reduction in Intracellular Reactive Oxygen Species Due to a Mutation in NCF4 Promotes Autoimmune Arthritis in Mice. (2016) (8)
- Therapeutic effects of monoclonal antibodies to alpha beta TCR but not to CD4 on collagen-induced arthritis in the rat. (1994) (8)
- Induction of Thy-1 antigen on murine keratinocytes. (1986) (8)
- Elucidation of pathways leading to rheumatoid arthritis by genetic analysis of animal models. (2001) (8)
- Production of monoclonal antibodies against gastric parietal cell antigens. (1992) (7)
- Reactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis (2018) (7)
- 17Beta-estradiol expands IgA-producing B cells in mice deficient for the mu chain. (2008) (7)
- A microELISA useful for determination of protein A-binding monoclonal antibodies. (1990) (7)
- Structural polymorphism of six rat RT1Ba genes (2004) (7)
- Collagen epitope expression on B cells is sufficient to confer tolerance to collagen-induced arthritis (2016) (7)
- A genetic basis for shared autoimmunity in mouse models (2005) (7)
- Oestrogen treatment reduces duration of experimental allergic neuritis in rats and suppresses T cell responses to myelin (1990) (7)
- A method for the analysis of a large number of specific and multispecific B cell hybridomas derived from primary immunized lymph nodes. (1987) (7)
- Aire‐ing self antigen variability and tolerance (2007) (7)
- Influence of hydrocarbon oil structure on adjuvanticity and autoimmunity (2017) (6)
- Spectrum of Anti Citrullinated Peptide Antibodies (ACPA) fine specificities is different between Malaysian and Swedish rheumatoid arthritis patients: Implications for pathogenesis of RA (2016) (6)
- IL‐21 and autoimmune disease – hypothesis and reality? (2008) (6)
- The anti-microbial peptide rCRAMP is strongly upregulated during experimental arthritis in the rat (2011) (6)
- Editorial: Oxidants and Redox Signaling in Inflammation (2019) (6)
- Genetic linkage analysis of the antibody responses to myelin basic protein and myelin oligodendrocyte glycoprotein in rats immunized with rat spinal cord homogenate (2001) (6)
- Polymorphic estrogen receptor binding site causes Cd2-dependent sex bias in the susceptibility to autoimmune diseases (2021) (6)
- Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor (2022) (6)
- Arthritis induced with minor cartilage proteins. (2007) (6)
- Type-II Collagen in the Pathogenesis of Rheumatoid Arthritis (1992) (6)
- Short‐Term Administration of Selected Anti‐T‐Cell Receptor Vβ Chain Specific MoAb Reduces Sialadenitis in MRL/lpr Mice (1995) (6)
- Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis. (2021) (6)
- Elimination of CD8+ T Cells in Vivo Does Not Break Induced Immunospecific Tolerance to Experimental Allergic Neuritis in Rats (1988) (5)
- Increased salt exposure affects both lymphoid and myeloid effector functions, influencing innate‐associated disease but not T‐cell‐associated autoimmunity (2018) (5)
- Effects of C2ta genetic polymorphisms on MHC class II expression and autoimmune diseases (2017) (5)
- Positive effects of anti-T-cell monoclonal antibodies on rat allograft survival. (1987) (5)
- Increased litter size and super-ovulation rate in congenic C57BL mice carrying a polymorphic fragment of NFR/N origin at the Fecq4 locus of chromosome 9. (2009) (5)
- Structure-immune response relationships of hapten-modified collagen II peptides in a T-cell model of allergic contact dermatitis. (2008) (5)
- Synovial class II antigen expression and immune complex formation in rheumatoid arthritis. (2009) (5)
- Analyses of association of psoriatic arthritis and psoriasis vulgaris with functional NCF1 variants. (2019) (5)
- Comment on editorial ‘Pathogenic effector functions of ACPA: where do we stand?’ (2019) (5)
- Incomplete B cell tolerance to cartilage oligomeric matrix protein in mice. (2013) (5)
- The hereditary basis of rheumatic diseases (2006) (5)
- An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation (2021) (5)
- Identification of New Loci Controlling Collagen‐induced Arthritis in Mouse Using a Partial Advanced Intercross and Congenic Strains (2008) (5)
- Genetic dissection of a major haplotype associated with arthritis reveal FcγR2b and FcγR3 to act additively (2020) (5)
- Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2-complex (2020) (5)
- RA-relevant T cell responses to type II collagen can be influenced by post-translational modifications. (2016) (5)
- Expression of a cell surface antigen with potential Ca2+-sensor/receptor function in rat placenta and uterus. (1989) (4)
- Identification of hnRNP-A2 (RA33) as a major B-cell and T-cell autoantigen in pristane–induced arthritis (2005) (4)
- Independent and inter-dependent immunoregulatory effects of NCF1 and NOS2 in experimental autoimmune encephalomyelitis (2020) (4)
- Antibodies to Cartilage Oligomeric Matrix Protein Are Pathogenic in Mice and May Be Clinically Relevant in Rheumatoid Arthritis (2022) (4)
- Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E 3 rats (2003) (4)
- Primer: comparative genetics of animal models of arthritis—a tool to resolve complexity (2007) (4)
- Frequency and phenotypic feature of autoantibody-producing cell precursors in the preclinical stage of murine lupus. (1990) (4)
- Regulation of the delayed hypersensitivity reaction in the lung reflected as mononuclear, mast cell and mucus cell appearance after T helper cell depletion and adoptive transfer. (1987) (4)
- Identification of Clec4b as a novel regulator of bystander activation of auto-reactive T cells and autoimmune disease (2020) (4)
- The rat as an experimental model for studies on immune regulating mechanisms in contact allergic reactions. (1988) (4)
- Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2 complex (2020) (4)
- Allopregnancy in mice treated with recombinant rat interferon-gamma (1989) (4)
- Effects on murine T helper cell proliferation by DTH activated syngeneic epidermal cells. (1986) (4)
- The use of animal models for rheumatoid arthritis. (2007) (4)
- VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis (2017) (4)
- Rheumatoid arthritis chondrocytes produce increased levels of pro-inflammatory proteins (2022) (4)
- Synthesis of an Array of Triple-Helical Peptides from Type II Collagen for Multiplex Analysis of Autoantibodies in Rheumatoid Arthritis. (2020) (4)
- Exercise-stimulated muscle ROS production and glucose uptake requires NADPH oxidase 2 (2019) (4)
- Rapid spread of mannan to the immune system, skin and joints within 6 hours after local exposure (2019) (4)
- Editorial: Autoantibodies (2019) (3)
- The Major Histocompatibility Complex Class III Haplotype Ltab-Ncr3 Regulates Adjuvant-Induced but Not Antigen-Induced Autoimmunity. (2017) (3)
- Reply to Liu et al.: Translation of rat congenic data to humans on a conserved MHC-III haplotype associated with rheumatoid arthritis (2016) (3)
- Regulatory T cells control epitope spreading in autoimmune arthritis independent of cytotoxic T‐lymphocyte antigen‐4 (2018) (3)
- Autoantibodies to disease-related proteins in joints as novel biomarkers for the diagnosis of rheumatoid arthritis. (2023) (3)
- Human type II collagen is processed in lysosomal compartments of macrophages for presentation of the glycosylated arthritogenic epitope hCII259–273 to CD4 T cells in HLA-DR1 transgenic mice (2005) (3)
- Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology (2022) (3)
- Standardization of Antigen-Emulsion Preparations for the Induction of Autoimmune Disease Models (2022) (3)
- Collagen induced arthritis : pathogenetic mechanisms and relevance for rheumatoid arthritis (1985) (3)
- Cartilage Oligomeric Matrix Protein Induced Arthritis—A New Model for Rheumatoid Arthritis in the C57BL/6 Mouse (2021) (3)
- Immunotherapy of collagen-induced arthritis by a T-cell antiproliferative molecule. (1990) (3)
- Identification and differentiation of transcribed major histocompatibility complex class II RT1Bα and RT1Bβ alleles from laboratory rats (1997) (3)
- Arthritis Susceptibility Loci for Pristane-Induced Identification and Isolation of Dominant Holmdahl (2003) (3)
- The Specificity of Monoclonal Anti–Citrullinated Protein Antibodies: Comment on the Article by Steen et al (2019) (3)
- Effects of Purified Protein Derivative (PPD)‐Activated Syngeneic Epidermal Cells on a PPD‐Specific Rat T‐Helper Cell Line (1989) (2)
- Nature's choice of genes controlling chronic inflammation. (2006) (2)
- OP0085 Multiplex analysis of antibodies against citrullinated peptides in individuals prior to development of rheumatoid arthritis (2013) (2)
- Endophilin A2 deficiency protects rodents from autoimmune arthritis by modulating T cell activation (2021) (2)
- Studies of Preclinical Rheumatoid Arthritis Synovial Histology—A Comparison of Animal Models: Comment on the Article by de Hair et al (2014) (2)
- A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis (2023) (2)
- CHAPTER 16 – Inbred Mouse Models for Autoimmune Disease (2004) (2)
- Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss (2016) (2)
- Keratinocyte growth factor (KGF) delays the onset of collagen-induced arthritis (2012) (2)
- A new model of arthritis induced by a glucose-6-phosphate isomerase peptide: immunological requirements and peptide characterisation (2012) (2)
- Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation (2022) (2)
- ROS is the boss (2017) (2)
- Role of superantigens in experimental arthritis (2005) (2)
- Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice (2021) (2)
- Cells in the Rat MHC Class II-Restricted, Arthritogenic T Pristane, a Non-Antigenic Adjuvant, Induces (2013) (2)
- Variants of beta-glucan polysaccharides downregulate autoimmune inflammation (2022) (2)
- Single Nucleotide Polymorphisms within the HLA-DRB1 Gene in Relation to Antibodies Against Citrullinated Peptides in Individuals Prior to the Development of Rheumatoid Arthritis (2012) (1)
- Rheumatoid arthritis sera antibodies to citrullinated collagen type II bind to joint cartilage (2022) (1)
- Animal models for rheumatoid arthritis (2015) (1)
- Cover Picture: ChemBioChem 12/2002 (2002) (1)
- The use of animal models to find and understand arthritis genes (2003) (1)
- MOG79–90 Peptide in Complex with Recombinant MHC Class II Molecules Ameliorates Experimental Autoimmune Encephalomyelitis (2010) (1)
- Collagen Antibody-Induced Arthritis: A Disease-Relevant Model for Studies of Persistent Joint Pain (2012) (1)
- Effects on experimental allergic neuritis in rats by in vivo treatment with monoclonal anti-T-cell antibodies (1987) (1)
- Dynamics Determine Signaling in a Multicomponent System Associated with Rheumatoid Arthritis. (2018) (1)
- REPRODUCTION IN IMMUNOGLOBULIN-DEFICIENT MICE: A ROLE FOR TRANSMITTED IGG IN NEONATAL GROWTH (1994) (1)
- Monoclonal anti t cell antibodies for in vivo treatment of rats with experimental allergic neuritis ean (1986) (1)
- Collagen antibody-induced arthritis (CAIA) leads to evoked and ongoing persistent pain-like behavior, but transient joint inflammation (2012) (1)
- Antibodies against native collagen and citrullinated proteins precede the development of rheumatoid arthritis with a consecutive pattern (2012) (1)
- Role of anti-hinge antibodies in therapeutic cleavage of IgG: response to Drs. Lutz and Fumia (2008) (1)
- Collagen antibody-induced arthritis (CAIA) evokes transient inflammation but persistent allodynia (2011) (1)
- Hydroxyethylene isosteres introduced in type II collagen fragments substantially alter the structure and dynamics of class II MHC A(q)/glycopeptide complexes. (2015) (1)
- Antileukoproteinase: modulation of neutrophil function and therapeutic effects in anticollagen II antibody-induced arthritis (2003) (1)
- Ncf 1-Associated Reduced Oxidative Burst Promotes IL-33 R T Cell-Mediated Adjuvant-Free Arthritis in Mice 1 , 2 (2009) (1)
- Identification of arthritis promoting non-obese diabetic genes in the Cia9 locus using different genetic strategies (2012) (1)
- diseases and reproductive performance in the mouse (2009) (1)
- Characterization of chronic relapsing antibody mediated arthritis in mice with a mutation in Ncf1 causing reduced oxidative burst (2022) (1)
- Influence of T-cell receptor genes on chronic experimental autoimmune encephalomyelitis (2004) (1)
- Immunogenetics of collagen induced arthritis in mice (1990) (1)
- Third Eular Workshop on Rheumatology Research (1983) (1)
- Identification and differentiation of transcribed major histocompatibility complex class II RT1B alpha and RT1B beta alleles from laboratory rats. (1997) (1)
- The antimicrobial peptide rCRAMP is strongly upregulated during experimental arthritis in the rat (2012) (1)
- Role of anti-hinge antibodies in therapeutic cleavage of IgG: response to Drs. Lutz and Fumia (2008) (1)
- Comprehensive Invited Review Rheumatoid Arthritis: The Role of Reactive Oxygen Species in Disease Development and Therapeutic Strategies (2007) (1)
- S188 COLLAGEN ANTIBODY-INDUCED ARTHRITIS EVOKES PERSISTENT ALLODYNIA WITH A TRANSIENT PROSTAGLANDIN DEPENDENCE AND SPINAL ASTROCYTE INVOLVEMENT IN THE “POST-INFLAMMATORY” PHASE (2011) (1)
- Correction to Synthesis of an Array of Triple-Helical Peptides from Type II Collagen for Multiplex Analysis of Autoantibodies in Rheumatoid Arthritis. (2020) (1)
- Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defi ned by the anticitrullinated protein / peptide antibody fi ne specifi city profi (2012) (1)
- An encephalomyelitis-specific locus on chromosome 16 in mouse controls disease development and expression of immune-regulatory genes (2011) (1)
- 28 – Experimental Models for Rheumatoid Arthritis (2013) (1)
- P86 The NCF1–339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus (2020) (1)
- OP0084 Patterns of circulating antibodies in the pre-clinical phase of rheumatoid arthritis suggest epitope spreading in the immune reaction against citrullinated peptides (2013) (0)
- Protect Mice from Bacterial Infections NADPH Oxidase 2 Complex in Monocytes Reactive Oxygen Species Produced by the (2012) (0)
- Disease in a Murine Psoriasis Model Identification of Susceptibility Loci for Skin (2006) (0)
- Two major genes associated with autoimmune arthritis, Ncf1 and Fcgr2b, additively protect mice by strengthening T cell tolerance (2022) (0)
- Independent and inter-dependent immunoregulatory effects of NCF1 and NOS2 in experimental autoimmune encephalomyelitis (2020) (0)
- Collagen Type II-Specific Autoantibodies in Chronic Inflammatory Joint Diseases (1999) (0)
- Genetics of autoimmunity (PP-018) (2010) (0)
- Post-translational modification of type II collagen influences T-cell tolerance to self-type II collagen (2003) (0)
- Genetic Studies in Experimental Arthritis (1999) (0)
- Tolerogenic vaccine targeting antigen presenting as an arthritis treatment. (2006) (0)
- Crystal structure of the RA-associated mAb B2 (Fab fragment) (2018) (0)
- OP0171 Screening for Anti-CCP in a Large Population Based Cohort and its Association with Prevalent Rheumatoid Arthritis (2013) (0)
- Correction: Pathogenic Autoreactive B Cells Are Not Negatively Selected toward Matrix Protein Collagen II (2012) (0)
- Commentary Rheumatoid arthritis viewed using a headache paradigm (2000) (0)
- Cancer Therapy : Preclinical Clever-1 / Stabilin-1 Controls Cancer Growth and Metastasis (2014) (0)
- Chapter 29 – Experimental Models for Rheumatoid Arthritis (2017) (0)
- EncephalomyelitisExperimental Autoimmune Oligodendrocyte Glycoprotein-Induced New Loci Regulating Rat Myelin (2002) (0)
- AB0040 Toll-like receptor 9 influences inflammatory arthritis and osteoclastogenesis (2018) (0)
- Conditional model to study the tissue- and time specific effects of nadph oxidase 2 -derived reactive oxygen species during arthritis (2012) (0)
- From disease to genes and back: Following an oxidation path (2008) (0)
- T cells specific for post-translational modifications escape intrathymic tolerance induction (2018) (0)
- Threonine 153 in P47(PHOX) Regulates ROS Production by the NADPH Oxidase NOX2 (2011) (0)
- Gender differences and the effect of sex hormones on collagen type ii induced arthritis in rats (1988) (0)
- Genetic control of arthritis in rats (2000) (0)
- Reveals a New Set of Interacting Subloci Loci Controlling Collagen-Induced Arthritis Fragmentation of Two Quantitative Trait (2007) (0)
- Abstract 129: Investigation of Atherosclerosis in Association with Arthritic Inflammation (2013) (0)
- Disease in a Murine Psoriasis Model Identification of Susceptibility Loci for Skin (2006) (0)
- Binding stretches of myelin basic protein define encephalitogenic T cell epitopes for RT1.B and RT1.D alleles of four different rat haplotypes (1998) (0)
- Methotrexate ameliorate T cell dependent autoimmune arthritis and encephalomyelitis but not antibody- or fibroblast-induced arthritis (2004) (0)
- Estrogens and Immunity: Long-Term Consequences of Neonatal Imprinting of the Immune System by Diethylstilbestrol (2020) (0)
- ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23) (2017) (0)
- Genetic control of T cell activation Implication for autoimmunity and cancer Lofoten, Norway, August 18th‐22th 2005 (2005) (0)
- Influence of hydrocarbon oil structure on adjuvanticity and autoimmunity (2017) (0)
- Effects by periodontitis on pristane-induced arthritis in rats (2016) (0)
- Crystal structure of the pathogenic autoantibody CIIC1 in complex with the triple-helical C1 peptide (2011) (0)
- A3.07 How well do acpa discriminate and predict ra in the general population -– a study based on 12,590 population-representative swedish twins (2016) (0)
- Platelets derived citrullinated proteins and microparticles are potential autoantibodies ACPA targets in RA patients (2023) (0)
- FRI0071 ANTI-CITRULLINATED PROTEIN ANTIBODY SPECIFICITIES, RHEUMATOID FACTOR ISOTYPES AND RISK OF MAJOR ADVERSE CARDIOVASCULAR EVENTS (2019) (0)
- Arthritis as Susceptibility Locus for Autoimmune ) HLA-DQ ( RT 1-B Positional Identification of Bäcklund (2015) (0)
- Novel quantitative trait loci controlling collagen-induced arthritis in mice (2008) (0)
- Mice Collagen-Induced Arthritis in Humanized Collagen-Specific T Cells in Early and Late Tracking of Proinflammatory (2004) (0)
- The presence of anti-carbamylated protein antibodies prior to onset of symptoms of rheumatoid arthritis (RA) is associated with radiological progression in early RA (2014) (0)
- Redox regulation of PTPN22 affects the severity of T cell dependent autoimmune inflammation (2021) (0)
- transplantable receptor gene in mice causes a lethal inflammatory disorder that is Induced disruption of the transforming growth factor beta type II (2010) (0)
- ROS-independent regulation of TLR9-induced IL-12p70 by Ncf in murine dendritic cells (2008) (0)
- Inhibition of NF kappa B leads to an intracellular reducing environment in human monocyte-derived immature dendritic cells (2005) (0)
- Studies on Collagen II Induced Arthritis in Mice and Rats (1986) (0)
- Inflammatory Disease in Rats Genetically Determined and Regulates TNF Production in Macrophages Is (2010) (0)
- Corrigendum to “NCF4 dependent intracellular reactive oxygen species regulate plasma cell formation” [Redox Biol 56 (2022) 102422] (2022) (0)
- Crystal structure of ACPA E4 in complex with CII-C-13-CIT (2018) (0)
- Autologous Collagen-Induced Arthritis Collagen and Development of Arthritis in an Genetic Control of Tolerance to Type II (2013) (0)
- DISEASE MODELS Drug Discovery Today : Disease Models (2017) (0)
- Genetics of joint inflammation — problems and possibilities (2006) (0)
- MOG 79-90 PEPTIDE IN COMPLEX WITH RECOMBINANT MHC CLASS II MOLECULES AMELIORATES EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS (2010) (0)
- Frequency andphenotypic feature ofautoantibody-producing precursorsinthepreclinical stageofmurinelupus (1990) (0)
- POS0515 THE ASSOCIATION BETWEEN AUTOANTIBODIES AND RISK FOR VENOUS THROMBOEMBOLIC EVENTS AMONG PATIENTS WITH RHEUMATOID ARTHRITIS (2022) (0)
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- Human chromosome 18q12-q21 and distal rodent chromosome 18 are associated with multiple autoimmune phenotypes. (1999) (0)
- Autoreactive B Cells in Collagen-Induced Arthritis (2020) (0)
- Antigen receptor stimulation drives selection against pathogenic mtDNA variants that dysregulate lymphocyte responses (2021) (0)
- ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (CG05) (2017) (0)
- OP0307 PULMONARY FIBROSIS IN EARLY RHEUMATOID ARTHRITIS IN RELATION TO GENETIC LOCI AND INDIVIDUAL ACPA SPECIFICITIES (2022) (0)
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- Interaction of Antibodies Against Citrullinated Peptides with HLA Shared Epitope, PTPN22 1858T Variant, and Smoking in Individuals Prior to and After the Development of Rheumatoid Arthritis. (2012) (0)
- Chronicity Based on Experimental Models Genes Controlling Onset, Severity, and Evidence for Common Autoimmune Disease (2000) (0)
- Collagen II Negatively Selected toward Matrix Protein Pathogenic Autoreactive B Cells Are Not (2011) (0)
- Genetic dissection of immune system genes associated with experimental allergic encephalomyelitis by using multi-phenotype linkage analysis in rats (1999) (0)
- Anti citrullinated Collagen type 2 antibody acc4 in complex with a citrullinated peptide (2009) (0)
- Allows Development of Arthritis in Mice Cell Tolerance to Collagen Type II and Lack of Reactive Oxygen Species Breaks T (0)
- Identified in the Rat Homology with Susceptibility Loci Previously Collagen-Induced Arthritis in Mice: Striking Identification of Genes Controlling (1999) (0)
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- Disease in a Murine Psoriasis Model Identification of Susceptibility Loci for Skin (2006) (0)
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- Rheumatoid arthritis and other inflammatory joint diseases (animal models) (PP-037) (2010) (0)
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- NCF4 dependent intracellular reactive oxygen species regulate plasma cell formation (2022) (0)
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- Early Menopause, Smoking and Circulating Antibodies Against Citrullinated Peptides in the Pre-Clinical Phase of Rheumatoid Arthritis (2012) (0)
- Disease in a Murine Psoriasis Model Identification of Susceptibility Loci for Skin (2006) (0)
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- experimental arthritis in mice C4b-binding protein (C4BP) inhibits development of (2008) (0)
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- Reply (2016) (0)
- Frontline : The major T cell epitope on type II collagen is glycosylated in normal cartilage butmodified by arthritis in both rats and humans (2005) (0)
- At last — rats lacking B cells (2010) (0)
- Establishment of T Cell Hybridomas and Measurement of T Cell Hybridoma Response (2003) (0)
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- Arthritis susceptibility in mice transgenic for human type II collagen (1997) (0)
- Glycan Activation of Clec4b Induces Reactive Oxygen Species Protecting against Neutrophilia and Arthritis (2021) (0)
- Letters to the editor (1992) (0)
- THU0078 Interactions of Antibodies Against Citrullinated Peptides with HLA Shared Epitope, PTPN22 1858T Variant, and Smoking in Individuals Prior to and after the Development of Rheumatoid Arthritis (2013) (0)
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- Multivariate design synthesis and biological evaluation of peptides binding to Aq class II MHC molecules : a QSAR model for peptide binding in a mouse model for rheumatoid arthritis. (2006) (0)
- Arthritis development in germ free mice deficient for reactive oxygen species (2012) (0)
- Suppressor Cells + CD 152-Dependent CD 4 Collagen-Induced Arthritis Is Generated by Intrinsic Tolerance in Autologous and Shohreh Issazadeh-Navikas (2005) (0)
- In Honour of Paul Kallós (1987) (0)
- Oestrogen isa potentdisease accelerator inSLE-prone MRL lpr/lpr mice (1990) (0)
- Experimental allergic neuritis: Dynamics of Ia‐expressing cells, T lymphocytes of different subsets in peripheral nerve tissue and serum IgG response (1984) (0)
- Crystal structure of the arthritogenic antibody M2139 (Fab fragment) in complex with the triple-helical J1 peptide (2014) (0)
- Pristane-Induced Arthritis Stimulator of Autoimmunity in Rats with Autoantigen hnRNP-A 2 ( RA 33 ) Is a Major The Rheumatoid Arthritis-Associated and Günter (2007) (0)
- Effects on Experimental Allergic Neuritis in Rats by in Vivo Treatment with Monoclonal Anti‐T‐Cell Antibodies (1988) (0)
- A6.2 The NADPH oxidase 2 (NOX2) mediates an anti-inflammatory response to dead cell debris (2015) (0)
- Anti citrullinated Collagen type 2 antibody acc4 (2009) (0)
- Localization of a critical restriction site on the IAp chain that determines susceptibility to collagen-induced arthritis in mice ( major histocompatibility complex / class H genes / polymerase chain reaction / anticollagen autoantibodies / type II collagen-induced arthritis ) (0)
- Correction: A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis (2011) (0)
- Pain mechanisms in animal models of rheumatoid arthritis (2010) (0)
- Abstract 23: Identification of NCF4 as a Novel Regulator in Arterial Remodeling and Advanced Atherosclerosis (2017) (0)
- Murine Dendritic Cells Regulation of TLR 9-Induced IL-12 p 70 in Species-Independent Negative Feedback Provides a Reactive Oxygen Ncf 1 (2009) (0)
- Structure of anti-collagen type II FAb CIIC1 (2008) (0)
- Lymphocyte Subpopulations Encephalomyelitis and Proportion of Development of Experimental Autoimmune Novel Quantitative Trait Loci Controlling (2002) (0)
- The role of ncf1 in dendritic cell's antigen presentation (2008) (0)
- Crystal structure of ACPA E4 in complex with CEP1 (2018) (0)
- Development of Collagen II (CII)‐induced Arthritis Was Associated with High AID and IL‐17 Expression in BXD2 Mice (2008) (0)
- Encephalomyelitis Genes for Experimental Autoimmune as Candidate CLDN 4 and Ncf-1 Reveals Eae 5 Advanced Intercross Line Mapping of (2006) (0)
- P020 Toll-like receptor 9 influences inflammatory arthritis and osteoclastogenesis (2018) (0)
- VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis (2017) (0)
- Identification of genetic loci associated with antibodies to specific sets of citrullinated peptides in rheumatoid arthritis patients (2021) (0)
- SP0077 Innate versus adaptive immunity in the pathogenesis of arthritis (2001) (0)
- T173 PERSISTENT PAIN‐LIKE BEHAVIOR AND REDUCED LOCOMOTION, BUT TRANSIENT JOINT INFLAMMATION, IN THE COLLAGEN ANTIBODY‐INDUCED ARTHRITIS (CAIA) MOUSE MODEL (2011) (0)
- Contents, Vol. 82, 1987 (1987) (0)
- SAT0031 Detection and isolation of antigen specific b cells in patients with rheumatoid arthritis (2017) (0)
- Abstract 636: Accelerated Atherosclerosis in the Context of Rheumatoid Arthritis (2016) (0)
- The development of LLC tumors is restricted in the absence of functional NOX2 complex. (2013) (0)
- Glycopeptide Specificity of Helper T Cells Obtained in Mouse Models for Rheumatoid Arthritis. (2003) (0)
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