Rino Rappuoli
#12,811
Most Influential Person Now
Italian medical researcher
Rino Rappuoli's AcademicInfluence.com Rankings
Rino Rappuolimedical Degrees
Medical
#233
World Rank
#349
Historical Rank
Epidemiology
#65
World Rank
#73
Historical Rank
Rino Rappuolilaw Degrees
Law
#1046
World Rank
#1347
Historical Rank
Common Law
#11
World Rank
#12
Historical Rank
Jurisprudence
#11
World Rank
#36
Historical Rank
International Law
#90
World Rank
#133
Historical Rank
Download Badge
Medical Law
Rino Rappuoli's Degrees
- Doctorate Medicine University of Siena
- PhD Biotechnology University of Siena
Why Is Rino Rappuoli Influential?
(Suggest an Edit or Addition)According to Wikipedia, Rino Rappuoli is an Italian immunologist. He is the head of vaccine research and development at GlaxoSmithKline Vaccines. Previously, he has served as visiting scientist at Rockefeller University and Harvard Medical School and held roles at Sclavo, Vaccine Research and CSO, Chiron Corporation, and Novartis Vaccines.
Rino Rappuoli's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome". (2005) (2003)
- cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. (1996) (1992)
- Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. (2000) (1284)
- Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. (2000) (1150)
- Helicobacter pylori virulence and genetic geography. (1999) (1113)
- The microbial pan-genome. (2005) (1052)
- A universal vaccine for serogroup B meningococcus. (2006) (723)
- An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus (2004) (698)
- New Generation Vaccines (1990) (676)
- Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation. (2000) (620)
- Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin (1995) (618)
- Development of a mouse model of Helicobacter pylori infection that mimics human disease (1995) (590)
- Identification of a Universal Group B Streptococcus Vaccine by Multiple Genome Screen (2005) (546)
- Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients (2007) (529)
- Living dangerously: how Helicobacter pylori survives in the human stomach (2001) (519)
- COVID-19 vaccines: where we stand and challenges ahead (2021) (510)
- Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae (2002) (502)
- Reverse vaccinology. (2003) (490)
- A pneumococcal pilus influences virulence and host inflammatory responses. (2006) (487)
- SARS — beginning to understand a new virus (2003) (481)
- Nonviral delivery of self-amplifying RNA vaccines (2012) (465)
- Molecular and cellular signatures of human vaccine adjuvants (2008) (451)
- c‐Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs (2002) (447)
- Vaccination against Neisseria meningitidis Using Three Variants of the Lipoprotein GNA1870 (2003) (439)
- Pili in Gram-positive pathogens (2006) (434)
- Reverse vaccinology: developing vaccines in the era of genomics. (2010) (427)
- A novel glyco-conjugate vaccine against fungal pathogens (2005) (418)
- New adjuvants for human vaccines. (2010) (381)
- Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype. (1995) (376)
- NadA, a Novel Vaccine Candidate of Neisseria meningitidis (2002) (373)
- Correlates of adjuvanticity: A review on adjuvants in licensed vaccines. (2018) (372)
- Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species (2010) (349)
- Microbiology in the post-genomic era (2008) (343)
- Group B Streptococcus: global incidence and vaccine development (2006) (335)
- Genome Analysis Reveals Pili in Group B Streptococcus (2005) (330)
- Vaccines for the 21st century (2014) (328)
- MF59 Adjuvant Enhances Diversity and Affinity of Antibody-Mediated Immune Response to Pandemic Influenza Vaccines (2011) (327)
- Filamentous hemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence. (1989) (325)
- The Neutrophil-Activating Protein (Hp-Nap) of Helicobacter pylori Is a Protective Antigen and a Major Virulence Factor (2000) (322)
- The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: immunological, functional and structural characterization of the antigens. (2012) (320)
- Vaccine manufacturing: challenges and solutions (2006) (319)
- Reverse vaccinology: a genome-based approach for vaccine development (2002) (316)
- Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication. (1986) (314)
- Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants. (2001) (313)
- Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines (2010) (306)
- Selective Inhibition of Ii-dependent Antigen Presentation by Helicobacter pylori Toxin VacA (1998) (298)
- Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment. (2013) (298)
- Mucosal Adjuvanticity and Immunogenicity of LTR72, a Novel Mutant of Escherichia coli Heat-labile Enterotoxin with Partial Knockout of ADP-ribosyltransferase Activity (1998) (296)
- Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants. (1995) (296)
- Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transduction proteins. (1989) (295)
- Vaccines for the twenty-first century society (2011) (290)
- Transient Facial Nerve Paralysis (Bell's Palsy) following Intranasal Delivery of a Genetically Detoxified Mutant of Escherichia coli Heat Labile Toxin (2009) (289)
- Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins. (1999) (289)
- Hemagglutination Inhibition Antibody Titers as a Correlate of Protection for Inactivated Influenza Vaccines in Children (2011) (283)
- Formation of anion‐selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity (1999) (274)
- Reverse vaccinology : Genomics (2000) (272)
- Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design (2016) (270)
- Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels (2009) (264)
- Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin. (1998) (257)
- Vaccines with MF59 Adjuvant Expand the Antibody Repertoire to Target Protective Sites of Pandemic Avian H5N1 Influenza Virus (2010) (251)
- The history of MF59® adjuvant: a phoenix that arose from the ashes (2013) (249)
- A 2020 vision for vaccines against HIV, tuberculosis and malaria (2011) (248)
- Neisseria meningitidis NadA is a new invasin which promotes bacterial adhesion to and penetration into human epithelial cells (2004) (248)
- SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma (2020) (246)
- Counterselectable Markers: Untapped Tools for Bacterial Genetics and Pathogenesis (1998) (245)
- Invariant NKT cells sustain specific B cell responses and memory (2007) (244)
- Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli (2010) (244)
- Repeat‐associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58 (2000) (241)
- The design of vaccines against Helicobacter pylori and their development. (2001) (238)
- Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers (2011) (234)
- Reverse vaccinology: a genome-based approach for vaccine development. (2001) (231)
- Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments. (1994) (228)
- Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans (2010) (226)
- The amino-acid sequence of two non-toxic mutants of diphtheria toxin: CRM45 and CRM197. (1984) (226)
- Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant (1996) (225)
- Vaccines, new opportunities for a new society (2014) (223)
- Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2 (2015) (223)
- Low pH Activates the Vacuolating Toxin of Helicobacter pylori, Which Becomes Acid and Pepsin Resistant (*) (1995) (219)
- The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin (1997) (219)
- Alum adjuvanticity: Unraveling a century old mystery (2008) (214)
- Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes (1987) (212)
- The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity. (1998) (211)
- Identification of iron-activated and -repressed Fur-dependent genes by transcriptome analysis of Neisseria meningitidis group B (2003) (210)
- Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease (1995) (209)
- Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination (2011) (209)
- Strategic priorities for respiratory syncytial virus (RSV) vaccine development (2013) (209)
- The Fur repressor controls transcription of iron‐activated and ‐repressed genes in Helicobacter pylori (2001) (208)
- Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays (2002) (208)
- Vacuoles Induced by Helicobacter pylori Toxin Contain Both Late Endosomal and Lysosomal Markers* (1997) (203)
- A Second Pilus Type in Streptococcus pneumoniae Is Prevalent in Emerging Serotypes and Mediates Adhesion to Host Cells (2008) (195)
- Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin (1996) (194)
- Mucosal Administration of Ag85B-ESAT-6 Protects against Infection with Mycobacterium tuberculosis and Boosts Prior Bacillus Calmette-Guérin Immunity1 (2006) (191)
- Bridging the knowledge gaps in vaccine design (2007) (190)
- Developing vaccines in the era of genomics: a decade of reverse vaccinology. (2012) (189)
- Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection (1997) (189)
- Fur functions as an activator and as a repressor of putative virulence genes in Neisseria meningitidis (2004) (189)
- Adjuvanting a subunit COVID-19 vaccine to induce protective immunity (2021) (188)
- Intranasal immunogenicity and adjuvanticity of site-directed mutant derivatives of cholera toxin (1997) (184)
- Rapidly produced SAM® vaccine against H7N9 influenza is immunogenic in mice (2013) (184)
- Neisseria meningitidis group B correlates of protection and assay standardization--international meeting report Emory University, Atlanta, Georgia, United States, 16-17 March 2005. (2006) (184)
- Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host (2011) (184)
- Families of bacterial signal‐transducing proteins (1989) (183)
- Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to influenza vaccine in mice. (2008) (183)
- Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant. (1998) (182)
- Development and phase 1 clinical testing of a conjugate vaccine against meningococcus A and C. (1992) (180)
- Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori. (1995) (180)
- Pertussis toxin potentiates Th1 and Th2 responses to co-injected antigen: adjuvant action is associated with enhanced regulatory cytokine production and expression of the co-stimulatory molecules B7-1, B7-2 and CD28. (1998) (180)
- Safety and immunogenicity of an intramuscular Helicobacter pylori vaccine in noninfected volunteers: a phase I study. (2008) (176)
- Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens (2016) (176)
- RrgA is a pilus-associated adhesin in Streptococcus pneumoniae (2007) (176)
- The Helicobacter pylori neutrophil‐activating protein is an iron‐binding protein with dodecameric structure (1999) (172)
- Vaccinology in the genome era. (2009) (169)
- Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88 (2011) (168)
- Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics (2013) (168)
- The design of semi-synthetic and synthetic glycoconjugate vaccines (2011) (167)
- Cellular Microbiology Emerging (1996) (167)
- Did the inheritance of a pathogenicity island modify the virulence of Helicobacter pylori? (1997) (167)
- Influenza vaccine immunology (2011) (165)
- From empiricism to rational design: a personal perspective of the evolution of vaccine development (2014) (165)
- A mucosal vaccine against diphtheria: formulation of cross reacting material (CRM(197)) of diphtheria toxin with chitosan enhances local and systemic antibody and Th2 responses following nasal delivery. (2000) (158)
- Three conserved consensus sequences identify the NAD‐binding site of ADP‐ribosylating enzymes, expressed by eukaryotes, bacteria and T‐even bacteriophages (1996) (154)
- Structure-based antigen design: a strategy for next generation vaccines (2008) (154)
- The Intangible Value of Vaccination (2002) (151)
- Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus (2015) (151)
- Novel Approaches to Vaccine Delivery (2004) (150)
- Changing Priorities in Vaccinology: Antibiotic Resistance Moving to the Top (2018) (149)
- Helicobacter pylori vacuolating toxin forms anion-selective channels in planar lipid bilayers: possible implications for the mechanism of cellular vacuolation. (1999) (148)
- Emerging Vaccine Informatics (2011) (147)
- A Crisis of Public Confidence in Vaccines (2010) (147)
- Transcriptome Analysis of Neisseria meningitidis in Human Whole Blood and Mutagenesis Studies Identify Virulence Factors Involved in Blood Survival (2011) (146)
- Positive transcriptional feedback at the bvg locus controls expression of virulence factors in Bordetella pertussis. (1990) (146)
- Recombinant BCG Expressing LTAK63 Adjuvant induces Superior Protection against Mycobacterium tuberculosis (2017) (146)
- Antibody to genome-derived neisserial antigen 2132, a Neisseria meningitidis candidate vaccine, confers protection against bacteremia in the absence of complement-mediated bactericidal activity. (2003) (143)
- NadA Diversity and Carriage in Neisseria meningitidis (2004) (143)
- Streptococcus pneumoniae Pilus Subunits Protect Mice against Lethal Challenge (2006) (143)
- Structure of the neutrophil-activating protein from Helicobacter pylori. (2002) (141)
- Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity (2011) (141)
- Extremely potent human monoclonal antibodies from COVID-19 convalescent patients (2021) (140)
- Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections (2011) (139)
- The use of genomics in microbial vaccine development (2009) (137)
- Sequential activation and environmental regulation of virulence genes in Bordetella pertussis. (1991) (137)
- Post‐genomic vaccine development (2006) (136)
- Distribution and genetic variability of three vaccine components in a panel of strains representative of the diversity of serogroup B meningococcus. (2009) (132)
- Intranasal immunization with genetically detoxified diphtheria toxin induces T cell responses in humans: enhancement of Th2 responses and toxin-neutralizing antibodies by formulation with chitosan. (2004) (131)
- MF59 adjuvant: the best insurance against influenza strain diversity (2011) (131)
- Structural and biochemical studies of HCMV gH/gL/gO and Pentamer reveal mutually exclusive cell entry complexes (2015) (130)
- Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood (2016) (130)
- Helicobacter pylori toxin VacA induces vacuole formation by acting in the cell cytosol (1997) (129)
- Pneumococcal Pili Are Composed of Protofilaments Exposing Adhesive Clusters of Rrg A (2008) (129)
- Emerging infectious diseases: A proactive approach (2017) (128)
- Synthesis and Characterization of a Native, Oligomeric Form of Recombinant Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein (2004) (127)
- Bafilomycin A1 inhibits Helicobacter pylori‐induced vacuolization of HeLa cells (1993) (126)
- Two years into reverse vaccinology. (2003) (126)
- Mycobacterial heat‐shock proteins as carrier molecules. II: The use of the 70‐kDa mycobacterial heat‐shock protein as carrier for conjugated vaccinescan circumvent the need for adjuvants and Bacillus Calmette Guérin priming) (1992) (126)
- SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma (2021) (125)
- Stimulation of mucosal and systemic antibody responses against Bordetella pertussis filamentous haemagglutinin and recombinant pertussis toxin after nasal administration with chitosan in mice. (1998) (125)
- The Hsp60 protein of Helicobacter pylori: structure and immune response in patients with gastroduodenal diseases (1993) (124)
- Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen (2013) (124)
- Molecular mechanisms of complement evasion: learning from staphylococci and meningococci (2010) (124)
- Identification of the Helicobacter pylori VacA Toxin Domain Active in the Cell Cytosol (1998) (123)
- Comparative genomics of Neisseria meningitidis: core genome, islands of horizontal transfer and pathogen-specific genes. (2006) (123)
- Genetic characterization of Bordetella pertussis filamentous haemagglutinin: a protein processed from an unusually large precursor (1990) (122)
- Factor H-Binding Protein Is Important for Meningococcal Survival in Human Whole Blood and Serum and in the Presence of the Antimicrobial Peptide LL-37 (2008) (121)
- Effect of Helicobacter pylori Vacuolating Toxin on Maturation and Extracellular Release of Procathepsin D and on Epidermal Growth Factor Degradation* (1997) (121)
- Structural vaccinology starts to deliver (2012) (121)
- The Key Role of Genomics in Modern Vaccine and Drug Design for Emerging Infectious Diseases (2009) (120)
- The role of vaccines in combatting antimicrobial resistance (2021) (120)
- The Gracefully Aging Immune System (2013) (119)
- The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination (2013) (119)
- Glycoconjugate vaccines: Principles and mechanisms (2018) (118)
- A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit (1994) (117)
- The pan-genome: towards a knowledge-based discovery of novel targets for vaccines and antibacterials. (2007) (116)
- Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197 (2012) (116)
- An MF59-adjuvanted inactivated influenza vaccine containing A/Panama/1999 (H3N2) induced broader serological protection against heterovariant influenza virus strain A/Fujian/2002 than a subunit and a split influenza vaccine. (2006) (116)
- Technologies to address antimicrobial resistance (2018) (113)
- A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity, PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins (1995) (113)
- Probing the structure‐activity relationship of Escherichia coli LT‐A by site‐directed mutagenesis (1994) (113)
- Pertussis toxin export requires accessory genes located downstream from the pertussis toxin operon (1993) (113)
- Streptococcus pneumoniae contains 3 rlrA pilus variants that are clonally related. (2008) (112)
- Mutants of the Escherichia coli heat-labile enterotoxin as safe and strong adjuvants for intranasal delivery of vaccines (2003) (111)
- The concept of "tailor-made", protein-based, outer membrane vesicle vaccines against meningococcal disease. (2005) (110)
- Neisseria meningitidis NhhA is a multifunctional trimeric autotransporter adhesin (2006) (110)
- Common features of the NAD‐binding and catalytic site of ADP‐ribosylating toxins (1994) (109)
- Reverse vaccinology. (2000) (109)
- Prevalence and genetic diversity of candidate vaccine antigens among invasive Neisseria meningitidis isolates in the United States. (2011) (108)
- Molecular architecture of Streptococcus pneumoniae TIGR4 pili (2009) (108)
- Neisseria meningitidis App, a new adhesin with autocatalytic serine protease activity (2003) (108)
- Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses (2013) (108)
- Neisseria meningitidis: pathogenesis and immunity. (2015) (108)
- Ng‐MIP, a surface‐exposed lipoprotein of Neisseria gonorrhoeae, has a peptidyl‐prolyl cis/trans isomerase (PPIase) activity and is involved in persistence in macrophages (2005) (107)
- Beta-glucan-CRM197 conjugates as candidates antifungal vaccines. (2010) (107)
- Helicobacter pylori-specific CD4+ T-cell clones from peripheral blood and gastric biopsies (1995) (106)
- Mutants of Escherichia coli Heat-Labile Toxin Act as Effective Mucosal Adjuvants for Nasal Delivery of an Acellular Pertussis Vaccine: Differential Effects of the Nontoxic AB Complex and Enzyme Activity on Th1 and Th2 Cells (1999) (105)
- Vaccines, reverse vaccinology, and bacterial pathogenesis. (2013) (105)
- From Pasteur to genomics: progress and challenges in infectious diseases (2004) (104)
- The Helicobacter pylori VacA toxin is a urea permease that promotes urea diffusion across epithelia. (2001) (104)
- MHC class I-restricted cytotoxic lymphocyte responses induced by enterotoxin-based mucosal adjuvants. (1999) (103)
- Escherichia coli Heat-Labile Enterotoxin Promotes Protective Th17 Responses against Infection by Driving Innate IL-1 and IL-23 Production (2011) (103)
- Vaccinology at the beginning of the 21st century (2005) (103)
- Cell penetration of diphtheria toxin. Reduction of the interchain disulfide bridge is the rate-limiting step of translocation in the cytosol. (1993) (102)
- Vaccines and antibiotic resistance. (2012) (102)
- Subunit S1 of pertussis toxin: mapping of the regions essential for ADP-ribosyltransferase activity. (1988) (101)
- Reverse Vaccinology and Genomics (2003) (101)
- Introduction of unmarked mutations in the Helicobacter pylori vacA gene with a sucrose sensitivity marker (1997) (100)
- The acid activation of Helicobacter pylori toxin VacA: structural and membrane binding studies. (1998) (100)
- Therapeutic Vaccination against Helicobacter pylori in the Beagle Dog Experimental Model: Safety, Immunogenicity, and Efficacy (2004) (100)
- Protective Levels of Diphtheria-Neutralizing Antibody Induced in Healthy Volunteers by Unilateral Priming-Boosting Intranasal Immunization Associated with Restricted Ipsilateral Mucosal Secretory Immunoglobulin A (2003) (100)
- Unravelling the pathogenic role of Helicobacter pylori in peptic ulcer: potential new therapies and vaccines. (1994) (100)
- The Region Comprising Amino Acids 100 to 255 of Neisseria meningitidis Lipoprotein GNA 1870 Elicits Bactericidal Antibodies (2005) (99)
- Clonal success of piliated penicillin nonsusceptible pneumococci (2007) (98)
- The impact of genomics on vaccine design. (2005) (98)
- Modulation of Innate and Acquired Immune Responses by Escherichia coli Heat-Labile Toxin: Distinct Pro- and Anti-Inflammatory Effects of the Nontoxic AB Complex and the Enzyme Activity1 (2000) (98)
- Designing Vaccines for the Twenty-First Century Society (2013) (96)
- Measuring antigen-specific bactericidal responses to a multicomponent vaccine against serogroup B meningococcus. (2010) (96)
- In Vitro Analysis of Protein-Operator Interactions of the NikR and Fur Metal-Responsive Regulators of Coregulated Genes in Helicobacter pylori (2005) (96)
- Genome sequencing of disease and carriage isolates of nontypeable Haemophilus influenzae identifies discrete population structure (2014) (96)
- Positive regulation of pertussis toxin expression. (1988) (95)
- Identification and characterization of an operon of Helicobacter pylori that is involved in motility and stress adaptation (1997) (95)
- Antimicrobial resistance and the role of vaccines (2018) (94)
- Expression and immunological properties of the five subunits of pertussis toxin (1987) (94)
- Evaluation of the recombinant 38-kilodalton antigen of Mycobacterium tuberculosis as a potential immunodiagnostic reagent (1997) (94)
- Vaccine discovery and translation of new vaccine technology (2011) (93)
- Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies (1995) (93)
- Physicochemical characterisation of glycoconjugate vaccines for prevention of meningococcal diseases. (2008) (93)
- Structural and genetic analysis of the bvg locus in Bordetella species (1991) (93)
- Properties of pertussis toxin mutant PT-9K/129G after formaldehyde treatment (1991) (92)
- Tyrosine-Phosphorylated Bacterial Proteins (2000) (92)
- Dual RNA-seq of Nontypeable Haemophilus influenzae and Host Cell Transcriptomes Reveals Novel Insights into Host-Pathogen Cross Talk (2015) (91)
- Genetically Detoxified Mutants of Heat-Labile Toxin from Escherichia coli Are Able To Act as Oral Adjuvants (1999) (91)
- Biochemical and biological characteristics of cross-reacting material 197 CRM197, a non-toxic mutant of diphtheria toxin: use as a conjugation protein in vaccines and other potential clinical applications. (2011) (91)
- Immunobiology of Helicobacter pylori infection. (1997) (90)
- Cell Specificity of Helicobacter pyloriCytotoxin Is Determined by a Short Region in the Polymorphic Midregion (2000) (89)
- Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants (2021) (88)
- Molecular epidemiology of the 1984-1986 outbreak of diphtheria in Sweden. (1988) (88)
- In Vivo Dissection of the Helicobacter pylori Fur Regulatory Circuit by Genome-Wide Location Analysis (2006) (88)
- Vaccines in the era of genomics: the pneumococcal challenge. (2007) (88)
- The complete nucleotide sequence of the gene coding for diphtheria toxin in the corynephage omega (tox+) genome. (1983) (87)
- The concomitant use of the LTK63 mucosal adjuvant and of chitosan-based delivery system enhances the immunogenicity and efficacy of intranasally administered vaccines. (2003) (87)
- FdeC, a Novel Broadly Conserved Escherichia coli Adhesin Eliciting Protection against Urinary Tract Infections (2012) (87)
- Microbial genomes and vaccine design: refinements to the classical reverse vaccinology approach. (2006) (86)
- 3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin. (1999) (85)
- Development of vaccines against Helicobacter pylori (2009) (85)
- Phase variants of Bordetella bronchiseptica arise by spontaneous deletions in the vir locus (1989) (85)
- Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity. (1999) (85)
- Evolutionary relationships in the genus Bordetella (1987) (85)
- Reverse vaccinology in the 21st century: improvements over the original design (2013) (85)
- Chemistry of a new investigational quadrivalent meningococcal conjugate vaccine that is immunogenic at all ages. (2009) (85)
- Vaccines with the MF59 Adjuvant Do Not Stimulate Antibody Responses against Squalene (2006) (83)
- The neutrophil-activating protein of Helicobacter pylori. (2002) (83)
- Growth of Helicobacter pylori in media containing cyclodextrins (1993) (82)
- Intranasal Immunization with SAG1 and Nontoxic Mutant Heat-Labile Enterotoxins Protects Mice againstToxoplasma gondii (2001) (82)
- The neutrophil-activating protein (HP-NAP) of Helicobacter pylori is a potent stimulant of mast cells. (2002) (82)
- Recombinant Mycobacterium bovis BCG Expressing Pertussis Toxin Subunit S1 Induces Protection against an Intracerebral Challenge with Live Bordetella pertussisin Mice (2000) (82)
- Vi-CRM 197 as a new conjugate vaccine against Salmonella Typhi. (2011) (82)
- Construction of nontoxic derivatives of cholera toxin and characterization of the immunological response against the A subunit (1995) (81)
- Vaccine adjuvants: The dream becomes real (2008) (81)
- Dissecting human T cell responses against Bordetella species (1988) (80)
- Mucosal immunogenicity of genetically detoxified derivatives of heat labile toxin from Escherichia coli. (1998) (79)
- Towards deciphering the Helicobacter pylori cytotoxin (1999) (79)
- Sequence type 1 group B Streptococcus, an emerging cause of invasive disease in adults, evolves by small genetic changes (2015) (77)
- Chlamydia trachomatis control requires a vaccine. (2013) (77)
- Iron-Dependent Transcription of the frpB Gene ofHelicobacter pylori Is Controlled by the Fur Repressor Protein (2001) (77)
- Autoregulation of Helicobacter pylori Fur revealed by functional analysis of the iron‐binding site (2002) (76)
- A beta-glucan-conjugate vaccine and anti-beta-glucan antibodies are effective against murine vaginal candidiasis as assessed by a novel in vivo imaging technique. (2010) (76)
- Helicobacter pylori CagA: From Pathogenic Mechanisms to Its Use as an Anti-Cancer Vaccine (2013) (75)
- Genome-derived vaccines (2004) (75)
- Effect of Neisseria meningitidis Fur Mutations on Global Control of Gene Transcription (2006) (75)
- Influenza: Options to Improve Pandemic Preparation (2012) (73)
- The genome revolution in vaccine research. (2004) (73)
- Inhibition of the vacuolating and anion channel activities of the VacA toxin of Helicobacter pylori (1999) (72)
- On the mechanisms of conjugate vaccines (2018) (71)
- Characterization of Diverse Subvariants of the Meningococcal Factor H (fH) Binding Protein for Their Ability To Bind fH, To Mediate Serum Resistance, and To Induce Bactericidal Antibodies (2010) (71)
- Influence of Statins on Influenza Vaccine Response in Elderly Individuals. (2016) (71)
- Designing the next generation of vaccines for global public health. (2011) (71)
- Comparison of Open-Source Reverse Vaccinology Programs for Bacterial Vaccine Antigen Discovery (2019) (71)
- Formaldehyde treatment of proteins can constrain presentation to T cells by limiting antigen processing (1994) (70)
- Expression of factor H binding protein in meningococcal strains can vary at least 15-fold and is genetically determined (2016) (70)
- Inactivated and adjuvanted influenza vaccines. (2015) (70)
- A Conventional Beagle Dog Model for Acute and Chronic Infection with Helicobacter pylori (1999) (69)
- Vaccines and global health: In search of a sustainable model for vaccine development and delivery (2019) (68)
- Putative vaccine antigens from Neisseria meningitidis recognized by serum antibodies of young children convalescing after meningococcal disease. (2004) (68)
- Expression and immunogenicity of pertussis toxin S1 subunit-tetanus toxin fragment C fusions in Salmonella typhi vaccine strain CVD 908 (1996) (68)
- Helicobacter pylori: molecular evolution of a bacterial quasi-species. (1998) (68)
- Rational design of vaccines (1997) (68)
- Helicobacter pylori Interactions with Host Serum and Extracellular Matrix Proteins: Potential Role in the Infectious Process (2002) (67)
- Evaluation of a Group A Streptococcus synthetic oligosaccharide as vaccine candidate. (2010) (67)
- The adjuvant effect of a non‐toxic mutant of heat‐labile enterotoxin of Escherichia coli for the induction of measles virus‐specific CTL responses after intranasal co‐immunization with a synthetic peptide (1996) (66)
- Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal Salmonella (2018) (66)
- IgA-dependent cell-mediated activity against enteropathogenic bacteria: distribution, specificity, and characterization of the effector cells. (1984) (66)
- Genetically Detoxified Pertussis Toxin Induces Th1/Th17 Immune Response through MAPKs and IL-10-Dependent Mechanisms1 (2009) (66)
- The quest for a vaccine against Helicobacter pylori: how to move from mouse to man? (2003) (65)
- Interlaboratory Standardization of the Sandwich Enzyme-Linked Immunosorbent Assay Designed for MATS, a Rapid, Reproducible Method for Estimating the Strain Coverage of Investigational Vaccines (2012) (65)
- Three-dimensional reconstruction of metal replicas of the Helicobacter pylori vacuolating cytotoxin. (1998) (65)
- Generating memory with vaccination (2009) (65)
- CrgA Is an Inducible LysR-Type Regulator of Neisseria meningitidis, Acting both as a Repressor and as an Activator of Gene Transcription (2005) (65)
- The VacA toxin of Helicobacter pylori identifies a new intermediate filament‐interacting protein (2000) (65)
- Oil-in-Water Emulsion MF59 Increases Germinal Center B Cell Differentiation and Persistence in Response to Vaccination (2015) (64)
- Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum (2013) (64)
- On the membrane translocation of diphtheria toxin: at low pH the toxin induces ion channels on cells. (1988) (64)
- Computer modelling of the NAD binding site of ADP‐ribosylating toxins: active‐site structure and mechanism of NAD binding (1991) (63)
- Intranasal Immunization with Pneumococcal Polysaccharide Conjugate Vaccines with Nontoxic Mutants of Escherichia coliHeat-Labile Enterotoxins as Adjuvants Protects Mice against Invasive Pneumococcal Infections (1999) (63)
- Binding of the Helicobacter pyloriVacuolating Cytotoxin to Target Cells (1998) (63)
- Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen of Neisseria meningitidis* (2009) (63)
- Biotechnology and vaccines: application of functional genomics to Neisseria meningitidis and other bacterial pathogens. (2004) (63)
- Pseudoparticle neutralization is a reliable assay to measure immunity and cross-reactivity to H5N1 influenza viruses. (2009) (63)
- Mucosal Vaccination against Serogroup B Meningococci: Induction of Bactericidal Antibodies and Cellular Immunity following Intranasal Immunization with NadA of Neisseria meningitidis and Mutants of Escherichia coli Heat-Labile Enterotoxin (2004) (62)
- Combined Adenovirus Vector and Hepatitis C Virus Envelope Protein Prime-Boost Regimen Elicits T Cell and Neutralizing Antibody Immune Responses (2014) (62)
- Innate Imprinting by the Modified Heat-Labile Toxin of Escherichia coli (LTK63) Provides Generic Protection against Lung Infectious Disease1 (2004) (62)
- Immunization with the Chlamydia trachomatis major outer membrane protein, using adjuvants developed for human vaccines, can induce partial protection in a mouse model against a genital challenge. (2006) (61)
- Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody (2014) (61)
- Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus pneumoniae Pilus (2010) (61)
- Lipid interaction of the 37-kDa and 58-kDa fragments of the Helicobacter pylori cytotoxin. (1995) (61)
- Mapping of a Protective Epitope of Pertussis Toxin by In Vitro Refolding of Recombinant Fragments (1988) (61)
- Helicobacter pylori neutrophil-activating protein stimulates tissue factor and plasminogen activator inhibitor-2 production by human blood mononuclear cells. (2001) (61)
- Immunogenicity of meningococcal B polysaccharide conjugated to tetanus toxoid or CRM197 via adipic acid dihydrazide. (1995) (61)
- Human T cell clones define S1 subunit as the most immunogenic moiety of pertussis toxin and determine its epitope map (1989) (61)
- Conservation of Meningococcal Antigens in the Genus Neisseria (2013) (60)
- Safety of AS03-adjuvanted influenza vaccines: A review of the evidence. (2019) (60)
- Sequence constancies and variations in genes encoding three new meningococcal vaccine candidate antigens. (2006) (59)
- Group B Streptococcus crosses human epithelial cells by a paracellular route. (2006) (58)
- Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide. (2019) (58)
- Growth Phase-Dependent Regulation of Target Gene Promoters for Binding of the Essential Orphan Response Regulator HP1043 of Helicobacter pylori (2002) (58)
- Conjugates and reverse vaccinology to eliminate bacterial meningitis. (2001) (58)
- GNA33 of Neisseria meningitidis Is a Lipoprotein Required for Cell Separation, Membrane Architecture, and Virulence (2004) (58)
- The safety of vaccines (2004) (57)
- Transcutaneous immunization with tetanus toxoid and mutants of Escherichia coli heat-labile enterotoxin as adjuvants elicits strong protective antibody responses. (2003) (57)
- Synthesis, chemical and rheological characterization of new hyaluronic acid-based hydrogels (2000) (57)
- Lymphokine secretion and cytotoxic activity of human CD4+ T-cell clones against Bordetella pertussis (1991) (57)
- Promoter of the pertussis toxin operon and production of pertussis toxin (1987) (57)
- Levels of Expression and Immunogenicity of Attenuated Salmonella enterica Serovar Typhimurium Strains Expressing Escherichia coli Mutant Heat-Labile Enterotoxin (1998) (57)
- Identification of Neisseria meningitidis Nonlipopolysaccharide Ligands for Class A Macrophage Scavenger Receptor by Using a Novel Assay (2006) (57)
- SARS-CoV-2 escaped natural immunity, raising questions about vaccines and therapies (2021) (56)
- Prevalence and sequence variations of the genes encoding the five antigens included in the novel 5CVMB vaccine covering group B meningococcal disease. (2009) (56)
- Development of a glycoconjugate vaccine to prevent meningitis in Africa caused by meningococcal serogroup X (2013) (56)
- Induction of Protective Serum Meningococcal Bactericidal and Diphtheria-Neutralizing Antibodies and Mucosal Immunoglobulin A in Volunteers by Nasal Insufflations of the Neisseria meningitidis Serogroup C Polysaccharide-CRM197 Conjugate Vaccine Mixed with Chitosan (2005) (56)
- Mu-Like Prophage in Serogroup B Neisseria meningitidis Coding for Surface-Exposed Antigens (2001) (56)
- Transcriptional analysis of the divergent cagAB genes encoded by the pathogenicity island of Helicobacter pylori (1997) (56)
- Ageing and immunity: addressing immune senescence to ensure healthy ageing. (2010) (56)
- Size fractionation of bacterial capsular polysaccharides for their use in conjugate vaccines. (1999) (56)
- Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines (2021) (56)
- Differential binding of BvgA to two classes of virulence genes of Bordetella pertussis directs promoter selectivity by RNA polymerase (1996) (56)
- The adjuvants MF59 and LT-K63 enhance the mucosal and systemic immunogenicity of subunit influenza vaccine administered intranasally in mice. (1999) (55)
- Rationally designed strings of promiscuous CD4+ T cell epitopes provide help to Haemophilus influenzae type b oligosaccharide: a model for new conjugate vaccines (2001) (55)
- Neisseria Adhesin A Variation and Revised Nomenclature Scheme (2014) (54)
- Enhancement of Protective Efficacy following Intranasal Immunization with Vaccine Plus a Nontoxic LTK63 Mutant Delivered with Nanoparticles (2002) (54)
- Vaccines against Meningococcal Diseases (2020) (54)
- Reverse vaccinology and vaccines for serogroup B Neisseria meningitidis. (2005) (53)
- Haemophilus influenzae infections and whooping cough (1990) (53)
- Photolabeling of Glu-129 of the S-1 subunit of pertussis toxin with NAD (1989) (53)
- What are the limits of adjuvanticity? (2001) (53)
- Adhesion of Bordetella pertussis to eukaryotic cells requires a time-dependent export and maturation of filamentous hemagglutinin. (1993) (52)
- Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis. (2009) (52)
- Pertussis toxin promoter sequences involved in modulation (1989) (52)
- Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines (2021) (52)
- Emerging experience with meningococcal serogroup B protein vaccines (2017) (52)
- Toxin inactivation and antigen stabilization: two different uses of formaldehyde. (1994) (51)
- Influence of sequence variability on bactericidal activity sera induced by Factor H binding protein variant 1.1. (2011) (51)
- Guidebook to protein toxins and their use in cell biology (1997) (51)
- Deploy vaccines to fight superbugs (2017) (51)
- Histidine 21 is at the NAD+ binding site of diphtheria toxin. (1989) (50)
- The vacuolar ATPase proton pump is present on intracellular vacuoles induced by Helicobacter pylori. (1996) (50)
- Seasonal Influenza Vaccine Provides Priming for A/H1N1 Immunization (2009) (50)
- The neutrophil‐activating protein of Helicobacter pylori (HP‐NAP) activates the MAPK pathway in human neutrophils (2003) (50)
- Lipid interaction of diphtheria toxin and mutants with altered fragment B. 2. Hydrophobic photolabelling and cell intoxication. (1987) (50)
- Meningococcal B vaccine (4CMenB): the journey from research to real world experience (2018) (50)
- Identification of a new OmpA‐like protein in Neisseria gonorrhoeae involved in the binding to human epithelial cells and in vivo colonization (2007) (50)
- Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules (2021) (50)
- High-level expression of a proteolytically sensitive diphtheria toxin fragment in Escherichia coli (1987) (50)
- Properties of the B oligomer of pertussis toxin (1991) (50)
- Editorial: Reverse Vaccinology (2019) (50)
- Efficacy, immunogenicity, and safety of a parenteral vaccine against Helicobacter pylori in healthy volunteers challenged with a Cag-positive strain: a randomised, placebo-controlled phase 1/2 study. (2018) (50)
- The Iron-Responsive Regulator Fur Is Transcriptionally Autoregulated and Not Essential in Neisseria meningitidis (2003) (49)
- Vaccines for the twenty-first century society (2012) (49)
- A Novel Mimetic Antigen Eliciting Protective Antibody to Neisseria meningitidis1 (2001) (49)
- Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide (2017) (49)
- Vaccines Against Antimicrobial Resistance (2020) (48)
- Vaccines for the future: learning from human immunology (2012) (48)
- Enterotoxic effect of the vacuolating toxin produced by Helicobacter pylori in Caco-2 cells. (1998) (48)
- Inhibition of Helicobacter pylori urease by omeprazole (1993) (48)
- Pushing the limits of cellular microbiology: microarrays to study bacteria-host cell intimate contacts. (2000) (48)
- Genome‑based vaccine development: A short cut for the future (2008) (48)
- Protease susceptibility and toxicity of heat-labile enterotoxins with a mutation in the active site or in the protease-sensitive loop (1997) (48)
- Comparison of CRM197, diphtheria toxoid and tetanus toxoid as protein carriers for meningococcal glycoconjugate vaccines. (2013) (47)
- SARS Vaccine Protective in Mice (2005) (47)
- HIV-1 Tat Promotes Integrin-Mediated HIV Transmission to Dendritic Cells by Binding Env Spikes and Competes Neutralization by Anti-HIV Antibodies (2012) (47)
- Helicobacter pylori: host responses in peptic ulceration (1993) (46)
- RrgB321, a Fusion Protein of the Three Variants of the Pneumococcal Pilus Backbone RrgB, Is Protective In Vivo and Elicits Opsonic Antibodies (2011) (46)
- Efficacy of Vaccination with Different Combinations of MF59-Adjuvanted and Nonadjuvanted Seasonal and Pandemic Influenza Vaccines against Pandemic H1N1 (2009) Influenza Virus Infection in Ferrets (2011) (46)
- The cag Pathogenicity Island (2001) (46)
- NarE: a novel ADP‐ribosyltransferase from Neisseria meningitidis (2003) (46)
- An Analysis of the Sequence Variability of Meningococcal fHbp, NadA and NHBA over a 50-Year Period in the Netherlands (2013) (46)
- Priming to heat shock proteins in infants vaccinated against pertussis. (1993) (45)
- One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A (2016) (45)
- Application of microbial genomic science to advanced therapeutics. (2005) (45)
- Solution Structure of the Immunodominant Domain of Protective Antigen GNA1870 of Neisseria meningitidis* (2006) (45)
- Protective immune responses to meningococcal C conjugate vaccine after intranasal immunization of mice with the LTK63 mutant plus chitosan or trimethyl chitosan chloride as novel delivery platform (2005) (45)
- An anti‐repression Fur operator upstream of the promoter is required for iron‐mediated transcriptional autoregulation in Helicobacter pylori (2003) (45)
- The subunit S1 is important for pertussis toxin secretion. (1990) (45)
- Genetically derived toxoids for use as vaccines and adjuvants. (1999) (44)
- Correlates of protection against influenza infection in humans--on the path to a universal vaccine? (2013) (44)
- Protective Efficacy Induced by Recombinant Clostridium difficile Toxin Fragments (2013) (44)
- Modulation of immune response to group C meningococcal conjugate vaccine given intranasally to mice together with the LTK63 mucosal adjuvant and the trimethyl chitosan delivery system. (2004) (44)
- Vaccinology in the post−COVID-19 era (2021) (44)
- Isolation and characterization of Corynebacterium diphtheriae nontandem double lysogens hyperproducing CRM197 (1983) (44)
- Functional analysis of the Helicobacter pylori principal sigma subunit of RNA polymerase reveals that the spacer region is important for efficient transcription (1998) (44)
- Phase I clinical trial of an acellular pertussis vaccine composed of genetically detoxified pertussis toxin combined with FHA and 69 kDa. (1991) (44)
- HadA is an atypical new multifunctional trimeric coiled‐coil adhesin of Haemophilus influenzae biogroup aegyptius, which promotes entry into host cells (2009) (44)
- SR-A, MARCO and TLRs Differentially Recognise Selected Surface Proteins from Neisseria meningitidis: an Example of Fine Specificity in Microbial Ligand Recognition by Innate Immune Receptors (2008) (43)
- Modulation of the Immune Response to the Severe Acute Respiratory Syndrome Spike Glycoprotein by Gene-Based and Inactivated Virus Immunization (2005) (43)
- Comparative Systems Analyses Reveal Molecular Signatures of Clinically tested Vaccine Adjuvants (2016) (42)
- Absence of protective immunity against diphtheria in a large proportion of young adults. (1993) (42)
- Preclinical evaluation of group B Neisseria meningitidis and Escherichia coli K92 capsular polysaccharide-protein conjugate vaccines in juvenile rhesus monkeys (1997) (41)
- Role of O-Acetylation in the Immunogenicity of Bacterial Polysaccharide Vaccines (2018) (41)
- Induction of Neutralizing Antibodies against Diphtheria Toxin by Priming with Recombinant Mycobacterium bovis BCG Expressing CRM197, a Mutant Diphtheria Toxin (2001) (41)
- Neutrophil-activating protein (HP-NAP) versus ferritin (Pfr): comparison of synthesis in Helicobacter pylori. (2001) (41)
- Human protective response induced by meningococcus B vaccine is mediated by the synergy of multiple bactericidal epitopes (2018) (41)
- Acellular pertussis vaccine composed of genetically inactivated pertussis toxin: safety and immunogenicity in 12- to 24- and 2- to 4-month-old children. (1992) (41)
- Novel polysaccharide hydrogels: characterization and properties (2000) (40)
- The Human Pathogen Streptococcus pyogenes Releases Lipoproteins as Lipoprotein-rich Membrane Vesicles* (2015) (40)
- Novel approaches to pediatric vaccine delivery. (2006) (40)
- A novel epigenetic regulator associated with the hypervirulent Neisseria meningitidis clonal complex 41/44 (2011) (40)
- Mutations in the A subunit affect yield, stability, and protease sensitivity of nontoxic derivatives of heat-labile enterotoxin (1996) (40)
- Universal Vaccines: Shifting to One for Many (2010) (40)
- Phylogeny of the SARS Coronavirus (2003) (40)
- The diphtheria and pertussis components of diphtheria-tetanus toxoids-pertussis vaccine should be genetically inactivated mutant toxins. (2005) (40)
- Preparation, characterization and immunogenicity of HIV-1 related high-mannose oligosaccharides-CRM197 glycoconjugates (2010) (39)
- The response of primary articular chondrocytes to micrometric surface topography and sulphated hyaluronic acid‐based matrices (2005) (39)
- Influence of serogroup B meningococcal vaccine antigens on growth and survival of the meningococcus in vitro and in ex vivo and in vivo models of infection. (2010) (39)
- Long noncoding RNAs are involved in multiple immunological pathways in response to vaccination (2019) (39)
- GNA33 from Neisseria meningitidis serogroup B encodes a membrane-bound lytic transglycosylase (MltA). (2002) (39)
- The LTR72 Mutant of Heat-Labile Enterotoxin of Escherichia coli Enhances the Ability of Peptide Antigens To Elicit CD4+ T Cells and Secrete Gamma Interferon after Coapplication onto Bare Skin (2002) (38)
- Acellular pertussis vaccines containing genetically detoxified pertussis toxin induce long-lasting humoral and cellular responses in adults. (1997) (38)
- Response of the bvg regulon of Bordetella pertussis to different temperatures and short-term temperature shifts. (1995) (38)
- Immobilisation of sulphated hyaluronan for improved biocompatibility. (2000) (37)
- Integration of corynebacteriophages beta tox+, omega tox+, and gamma tox- into two attachment sites on the Corynebacterium diphtheriae chromosome (1983) (37)
- Genetics of pertussis toxin (1989) (37)
- Both Immunization with Protein and Recombinant Vaccinia Virus Can Stimulate CTL Specific for the E7 Protein of Human Papilloma Virus 16 in H‐2d Mice (1995) (37)
- Lipid interaction of diphtheria toxin and mutants with altered fragment B. 1. Liposome aggregation and fusion. (1987) (37)
- Pathogenicity mechanisms of Bordetella. (1994) (37)
- Cell vacuolization induced by Helicobacter pylori VacA toxin: cell line sensitivity and quantitative estimation. (1998) (36)
- Phagocyte subsets and lymphocyte clonal deletion behind ineffective immune response to Staphylococcus aureus. (2015) (36)
- Anticipating crisis: towards a pandemic flu vaccination strategy through alignment of public health and industrial policy. (2005) (36)
- Expression of fragment C of tetanus toxin fused to a carboxyl-terminal fragment of diphtheria toxin in Salmonella typhi CVD 908 vaccine strain. (1995) (36)
- Differential response of the bvg virulence regulon of Bordetella pertussis to MgSO4 modulation (1991) (36)
- Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines (2016) (35)
- Efficient production of heat-labile enterotoxin mutant proteins by overexpression of dsbA in a degP-deficient Escherichia coli strain (1997) (35)
- Escherichia coli: Great Diversity around a Common Core (2012) (35)
- Dual Control of Helicobacter pylori Heat Shock Gene Transcription by HspR and HrcA (2004) (35)
- Novel meningococcal 4CMenB vaccine antigens – prevalence and polymorphisms of the encoding genes in Neisseria gonorrhoeae (2012) (35)
- Medicine. The intangible value of vaccination. (2002) (34)
- Systems vaccinomics: the road ahead for vaccinology. (2011) (34)
- A Recombinant Live Attenuated Strain of Vibrio cholerae Induces Immunity against Tetanus Toxin andBordetella pertussis Tracheal Colonization Factor (1998) (34)
- Cloning of a novel pilin‐like gene from Bordetella pertussis: homology to the fim2 gene (1988) (34)
- LytM Proteins Play a Crucial Role in Cell Separation, Outer Membrane Composition, and Pathogenesis in Nontypeable Haemophilus influenzae (2015) (34)
- Recombinant bacterial vaccines. (2012) (34)
- Characterization of an IS-like element from Mycobacterium tuberculosis. (1993) (34)
- Pertussis toxin interferes with superantigen-induced deletion of peripheral T cells without affecting T cell activation in vivo. Inhibition of deletion and associated programmed cell death depends on ADP-ribosyltransferase activity. (1994) (33)
- Vaccines for Staphylococcus aureus and Target Populations. (2017) (33)
- Oral Spray Immunization May Be an Alternative to Intranasal Vaccine Delivery to Induce Systemic Antibodies but not Nasal Mucosal or Cellular Immunity (2006) (33)
- The Acquired Immune Response to the Mucosal Adjuvant LTK63 Imprints the Mouse Lung with a Protective Signature (2007) (33)
- Factor H-binding protein, a unique meningococcal vaccine antigen. (2008) (33)
- Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)‐mediated adhesion and invasion (2012) (33)
- Pertussis toxin activates platelets through an interaction with platelet glycoprotein Ib (1994) (33)
- Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly population (2020) (33)
- Detection in an enzyme immunoassay of an immune response to a recombinant fragment of the 128 kilodalton protein (CagA) ofHelicobacter pylori (1993) (33)
- DNA element of Corynebacterium diphtheriae with properties of an insertion sequence and usefulness for epidemiological studies (1987) (33)
- Vacuolation induced by VacA toxin of Helicobacter pylori requires the intracellular accumulation of membrane permeant bases, Cl− and water (2001) (33)
- Identification of errors among database sequence entries and comparison of correct amino acid sequences for the heat‐labile enterotoxins of Escherichia coli and Vibrio cholerae (1995) (33)
- The reaction of bacterial toxins with formaldehyde and its use for antigen stabilization. (1996) (33)
- The Binding Subunit of Pertussis Toxin Inhibits HIV Replication in Human Macrophages and Virus Expression in Chronically Infected Promonocytic U1 Cells1 (2001) (32)
- Sulphated hyaluronic acids : a chemical and biological characterisation (1998) (32)
- Mucosal delivery of the human immunodeficiency virus-1 Tat protein in mice elicits systemic neutralizing antibodies, cytotoxic T lymphocytes and mucosal IgA. (2003) (32)
- Progress towards the development of new vaccines against whooping cough. (1992) (32)
- Immunohistochemical Study of Lymphocyte Populations Infiltrating the Gastric Mucosa of Beagle Dogs Experimentally Infected withHelicobacter pylori (2000) (32)
- Mutations in the linker region of BvgS abolish response to environmental signals for the regulation of the virulence factors in Bordetella pertussis. (1995) (32)
- The multiple cellular activities of the VacA cytotoxin of Helicobacter pylori. (2004) (31)
- A ‘tailor made’ vaccine trialled as part of public health response to group B meningococcal epidemic in New Zealand (2003) (31)
- Combined Conjugate Vaccines: Enhanced Immunogenicity with the N19 Polyepitope as a Carrier Protein (2005) (31)
- A sweet T cell response (2011) (31)
- Isogenic mutants of the cag pathogenicity island of Helicobacter pylori in the mouse model of infection: effects on colonization efficiency. (2002) (31)
- Construction of a diphtheria toxin A fragment-C180 peptide fusion protein which elicits a neutralizing antibody response against diphtheria toxin and pertussis toxin (1992) (31)
- In silico identification of novel bacterial ADP-ribosyltransferases. (2004) (31)
- Heat-labile enterotoxin of Escherichia coli and its site-directed mutant LTK63 enhance the proliferative and cytotoxic T-cell responses to intranasally co-immunized synthetic peptides. (1999) (31)
- Characterization of the HspR-Mediated Stress Response in Helicobacter pylori (2002) (30)
- Environmental regulation of virulence factors in Bordetella species (1993) (30)
- Comparative analysis of the effects of locally used herbicides and their active ingredients on a wild-type wine Saccharomyces cerevisiae strain. (2006) (30)
- Diphtheria toxin and its mutant crm 197 differ in their interaction with lipids (1987) (30)
- Restriction endonuclease map of corynebacteriophage omega ctox+ isolated from the Park-Williams no. 8 strain of Corynebacterium diphtheriae (1983) (29)
- Deploy vaccines to fight superbugs. (2017) (29)
- Genetic detoxification of bacterial toxins: a new approach to vaccine development. (1995) (29)
- Lessons from Reverse Vaccinology for viral vaccine design. (2015) (29)
- Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C. (2004) (29)
- Mucosal and systemic immunogenicity of a recombinant, non-ADP-ribosylating pertussis toxin: effects of formaldehyde treatment. (1995) (29)
- Differences in the immunogenicity of native and formalinized cross reacting material (CRM197) of diphtheria toxin in mice and guinea pigs and their implications on the development and control of diphtheria vaccine based on CRMs. (1997) (29)
- Pathogenic mechanisms of Helicobacter pylori: production of cytotoxin. (1990) (29)
- Recognition of Neisseria meningitidis by the Long Pentraxin PTX3 and Its Role as an Endogenous Adjuvant (2015) (28)
- Signal Transduction and Bacterial Virulence (1995) (28)
- Characterization of the antibody response to pneumococcal glycoconjugates and the effect of heat-labile enterotoxin on IGg subclasses after intranasal immunization. (2001) (28)
- Reverse Vaccinology: Exploiting Genomes for Vaccine Design (2017) (28)
- Identification of neutralizing human monoclonal antibodies from Italian Covid-19 convalescent patients (2020) (28)
- Detoxification of the Helicobacter pylori cytotoxin (1997) (28)
- Immune response in COVID-19: what is next? (2022) (27)
- One dose of an MF59-adjuvanted pandemic A/H1N1 vaccine recruits pre-existing immune memory and induces the rapid rise of neutralizing antibodies. (2012) (27)
- Developing vaccines for an aging population (2015) (27)
- The neutrophil‐activating protein (HP‐NAP) of Helicobacter pylori is a potent stimulant of mast cells (2002) (27)
- Bacterial pathogen genomics and vaccines. (2002) (27)
- The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit. (1995) (27)
- Mutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli (1995) (27)
- N19 Polyepitope as a Carrier for Enhanced Immunogenicity and Protective Efficacy of Meningococcal Conjugate Vaccines (2004) (26)
- Helicobacter pylori Infection Negatively Influences Pregnancy Outcome in a Mouse Model (2004) (26)
- Bacterial Protein Toxins (2003) (26)
- Prevention and control of meningococcal outbreaks: The emerging role of serogroup B meningococcal vaccines. (2015) (26)
- Conformational changes in diphtheria toxoids (1987) (26)
- Vaccines: Science, health, longevity, and wealth (2014) (26)
- Transforming vaccine development (2020) (26)
- Successful induction of protective antibody responses against Haemophilus influenzae type b and diphtheria after transcutaneous immunization with the glycoconjugate polyribosyl ribitol phosphate-cross-reacting material 197 vaccine. (2004) (26)
- Vaccine Evolution and Its Application to Fight Modern Threats (2019) (26)
- Deletion of the Major Proteolytic Site of theHelicobacter pylori Cytotoxin Does Not Influence Toxin Activity but Favors Assembly of the Toxin into Hexameric Structures (1998) (26)
- Restriction map of corynebacteriophages beta c and beta vir and physical localization of the diphtheria tox operon (1981) (25)
- Cell vacuolization induced by Helicobacter pylori: inhibition by bafilomycins A1, B1, C1 and D. (1993) (25)
- Crystal structure of a non‐toxic mutant of heat‐labile enterotoxin, which is a potent mucosal adjuvant (1997) (25)
- Tyrosine 65 is photolabeled by 8-azidoadenine and 8-azidoadenosine at the NAD binding site of diphtheria toxin. (1991) (25)
- DNA topology affects transcriptional regulation of the pertussis toxin gene of Bordetella pertussis in Escherichia coli and in vitro (1993) (25)
- Helicobacter pylori vacuolating cytotoxin and associated pathogenic factors (1999) (24)
- Mucosal delivery of vaccines. (1999) (24)
- Physical map of the chromosomal region of Corynebacterium diphtheriae containing corynephage attachment sites attB1 and attB2 (1984) (24)
- LTK63 and LTR72, two mucosal adjuvants ready for clinical trials. (2000) (24)
- Cell entry machines: a common theme in nature? (2005) (24)
- Biochemical and biological characteristics of cross-reacting material 197 ( CRM 197 ) , a non-toxic mutant of diphtheria toxin : Use as a conjugation protein in vaccines and other potential clinical applications (2011) (23)
- Restriction endonuclease map of the nontoxigenic corynephage gamma c and its relationship to the toxigenic corynephage beta c (1982) (23)
- Functional analysis of the pertussis toxin promoter. (1992) (23)
- Multicomponent meningococcal serogroup B vaccination elicits cross-reactive immunity in infants against genetically diverse serogroup C, W and Y invasive disease isolates. (2020) (23)
- Vaccines: An achievement of civilization, a human right, our health insurance for the future (2018) (23)
- The role of structural proteomics in vaccine development: recent advances and future prospects (2016) (23)
- Vaccine candidates for poor nations are going to waste (2018) (23)
- Hydrophobic photolabelling of pertussis toxin subunits interacting with lipids (1986) (23)
- Acellular pertussis vaccine composed of genetically inactivated pertussis toxin. (1995) (23)
- Nuclear relaxation studies in ligand-macromolecule affinity index determinations (1997) (23)
- IEM101, a naturally attenuated Vibrio cholerae strain as carrier for genetically detoxified derivatives of cholera toxin. (2000) (22)
- Sustainable vaccine development: a vaccine manufacturer's perspective (2018) (22)
- Recombinant Mycobacterium bovis BCG Expressing Pertussis Toxin Subunit S1 Induces Protection against an Intracerebral Challenge with Live Bordetella pertussisin Mice (2001) (22)
- Structural insight into the mechanism of DNA-binding attenuation of the Neisserial adhesin repressor NadR by the small natural ligand 4-hydroxyphenylacetic acid. (2012) (22)
- Inner Workings: 1885, the first rabies vaccination in humans (2014) (22)
- Rapid purification of diphtheria toxin by phenyl sepharose and DEAE-cellulose chromatography (1983) (22)
- The bvg‐dependent promoters show similar behaviour in different Bordetella species and share sequence homologies (1991) (21)
- Towards third-generation whooping cough vaccines. (1991) (21)
- Pilus Operon Evolution in Streptococcus pneumoniae Is Driven by Positive Selection and Recombination (2008) (21)
- Food and Drug Administration Center for Biologics Evaluation and Research SUMMARY MINUTES VACCINES AND RELATED BIOLOGICAL PRODUCTS ADVISORY COMMITTEE Meeting # 104: November 16 - 17, 2005 Holiday Inn Select, Bethesda, MD (2005) (21)
- Transmission-Blocking Vaccines for Malaria: Time to Talk about Vaccine Introduction. (2019) (21)
- A Non-Living Nasal Influenza Vaccine Can Induce Major Humoral and Cellular Immune Responses in Humans without the Need for Adjuvants (2005) (21)
- Expression of the S-1 catalytic subunit of pertussis toxin in Escherichia coli (1987) (21)
- Toward a Meningitis-Free World (2012) (21)
- A tRNAArg2 gene of Corynebacterium diphtheriae is the chromosomal integration site for toxinogenic bacteriophages (1997) (21)
- The factor H binding protein of Neisseria meningitidis interacts with xenosiderophores in vitro. (2012) (21)
- Interaction of the pertussis toxin peptide containing residues 30-42 with DR1 and the T-cell receptors of 12 human T-cell clones. (1992) (21)
- HCV E1E2-MF59 vaccine in chronic hepatitis C patients treated with PEG-IFNα2a and Ribavirin: a randomized controlled trial (2013) (20)
- Effects of Site-Directed Mutagenesis ofEscherichia coli Heat-Labile Enterotoxin on ADP-Ribosyltransferase Activity and Interaction with ADP-Ribosylation Factors (1999) (20)
- ADITEC: Joining Forces for Next-Generation Vaccines (2012) (20)
- Reversal of the CD4+/CD8+T-Cell Ratio in Lymph Node Cells upon In Vitro Mitogenic Stimulation by Highly Purified, Water-Soluble S3-S4 Dimer of Pertussis Toxin (2001) (20)
- Ranking Vaccines: A Prioritization Software Tool: Phase II: Prototype of a Decision-Support System (2013) (20)
- Are serological responses to acellular pertussis antigens sufficient criteria to ensure that new combination vaccines are effective for prevention of disease? (1997) (20)
- Evolution of functional polymorphism in the gene coding for the Helicobacter pylori cytotoxin. (2002) (20)
- Thermoregulation and reversible differentiation in Bordetella: a model for pathogenic bacteria. (1992) (20)
- Intranasal Immunization with SAG 1 and Nontoxic Mutant Heat-Labile Enterotoxins Protects Mice against Toxoplasma gondii (2001) (20)
- Twenty-first century vaccines (2011) (20)
- Sortase A Confers Protection against Streptococcus pneumoniae in Mice (2009) (19)
- Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM197 conjugate vaccine (2020) (19)
- Molecular basis of vaccination. (1998) (19)
- The value of vaccines (2003) (19)
- Transcutaneous Immunization with Cross-Reacting Material CRM197 of Diphtheria Toxin Boosts Functional Antibody Levels in Mice Primed Parenterally with Adsorbed Diphtheria Toxoid Vaccine (2008) (19)
- Histidine-21 is involved in diphtheria toxin NAD+ binding. (1990) (19)
- A structural overview of the Helicobacter cytotoxin. (2000) (19)
- Acellular pertussis vaccines: a turning point in infant and adolescent vaccination. (1996) (19)
- Efficacy, safety, and immunogenicity of the Shigella sonnei 1790GAHB GMMA candidate vaccine: Results from a phase 2b randomized, placebo-controlled challenge study in adults (2021) (19)
- Role of ARF6, Rab11 and External Hsp90 in the Trafficking and Recycling of Recombinant-Soluble Neisseria meningitidis Adhesin A (rNadA) in Human Epithelial Cells (2014) (18)
- Long Covid: where we stand and challenges ahead (2022) (18)
- Adjuvant effect of non-toxic mutants of E. coli heat-labile enterotoxin following intranasal, oral and intravaginal immunization. (1998) (18)
- Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates (2021) (18)
- Development of V2-deleted trimeric envelope vaccine candidates from human immunodeficiency virus type 1 (HIV-1) subtypes B and C. (2005) (18)
- Antibodies Elicited by the Shigella sonnei GMMA Vaccine in Adults Trigger Complement-Mediated Serum Bactericidal Activity: Results From a Phase 1 Dose Escalation Trial Followed by a Booster Extension (2021) (18)
- Immunodominant antibody germlines in COVID-19 (2021) (18)
- Rethinking Influenza (2009) (18)
- The vaccine containing recombinant pertussis toxin induces early and long-lasting protection. (1999) (18)
- Monoclonal antibodies against pertussis toxin subunits (1988) (18)
- Lack of Interference with Immunogenicity of a Chimeric Alphavirus Replicon Particle-Based Influenza Vaccine by Preexisting Antivector Immunity (2012) (18)
- Vaccine Design: Innovative Approaches and Novel Strategies (2011) (17)
- Identification of subregions of Bordetella pertussis filamentous hemagglutinin that stimulate human T-cell responses (1991) (17)
- European Commission COST/STD Initiative. Report of the expert panel VIII. New vaccines, especially new combined vaccines. (1996) (17)
- Rational Design of a Glycoconjugate Vaccine against Group A Streptococcus (2020) (17)
- Development of an influenza virus protein array using Sortagging technology. (2012) (17)
- Detection of homology to the beta bacteriophage integration site in a wide variety of Corynebacterium spp (1986) (17)
- A novel chromatin‐forming histone H1 homologue is encoded by a dispensable and growth‐regulated gene in Bordetella pertussis (1995) (16)
- Vaccine Development: Current Status and Future Needs (2005) (16)
- Identification of Vaccine Targets (1998) (16)
- The challenge of developing universal vaccines (2011) (16)
- Self-Assembling Nanoparticles Usher in a New Era of Vaccine Design (2019) (16)
- CHAPTER 12 – Molecular, functional, and evolutionary aspects of ADP-ribosylating toxins (2006) (16)
- IL-1 stimulates a diverging signaling pathway in EL4 6.1 thymoma cells. IL-2 release, but not IL-2 receptor expression, is sensitive to pertussis toxin. (1995) (16)
- Faculty Opinions recommendation of Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. (2020) (16)
- SARS: understanding the virus and development of rational therapy. (2005) (16)
- Involvement of the intrinsic and extrinsic cell‐death pathways in the induction of apoptosis of mature lymphocytes by the Escherichia coli heat‐labile enterotoxin (2009) (16)
- Detection of a vacuolating cytotoxin in stools from children with diarrhea. (1996) (16)
- Cellular pertussis vaccine containing a Bordetella pertussis strain that produces a nontoxic pertussis toxin molecule (1992) (16)
- Structure of a protective epitope reveals the importance of acetylation of Neisseria meningitidis serogroup A capsular polysaccharide (2020) (15)
- Co‐Stimulation of T cells via CD28 inhibits human IgE production; reversal by Pertussis toxin (1995) (15)
- Bringing influenza vaccines into the 21st century (2014) (15)
- Characterisation of a monoclonal antibody and its use to purify the cytotoxin of Helicobacter pylori. (1998) (15)
- A common conserved amino acid motif module shared by bacterial and intercellular adhesins: bacterial adherence mimicking cell cell recognition? (2001) (15)
- Vir90, a virulence-activated gene coding for a Bordetella pertussis iron-regulated outer membrane protein. (2003) (15)
- Adjuvant is necessary for a robust immune response to a single dose of H1N1 pandemic flu vaccine in mice (2009) (15)
- Effect of heparin binding on Helicobacter pylori resistance to serum. (2004) (15)
- Characterization and Immunogenicity of the CagF Protein of the cag Pathogenicity Island of Helicobacter pylori (2002) (15)
- Big science for vaccine development. (2014) (15)
- Restriction Endonuclease Map of the Nontoxigenic Corynephage yc and Its Relationship to the Toxigenic Corynephage , Bc (14)
- TPA and butyrate increase cell sensitivity to the vacuolating toxin of Helicobacter pylori (1998) (14)
- Perspectives on vaccine development for the elderly. (2013) (14)
- Post-hoc analysis from phase III trials of human papillomavirus vaccines: considerations on impact on non-vaccine types (2019) (14)
- Expression and selective up‐regulation of toxin‐related mono ADP‐ribosyltransferases by pathogen‐associated molecular patterns in alveolar epithelial cells (2007) (14)
- Strategic Planning in Population Health and Public Health Practice: A Call to Action for Higher Education. (2016) (14)
- Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine (2022) (14)
- Multicriteria decision analysis and core values for enhancing vaccine-related decision-making (2016) (14)
- New biliary endoprosthesis less liable to block in biliary infections: description and in vitro studies. (1999) (14)
- Protein and Sugar Export and Assembly in Gram-positive Bacteria (2017) (14)
- A priority-setting aid for new vaccine candidates (2014) (14)
- Vaccines to Overcome Antibiotic Resistance: The Challenge of Burkholderia cenocepacia. (2020) (14)
- Faculty Opinions recommendation of Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells. (2006) (13)
- Beyond cost-effectiveness: Using systems analysis for infectious disease preparedness. (2017) (13)
- TIPICO IX: report of the 9th interactive infectious disease workshop on infectious diseases and vaccines (2019) (13)
- Vaccine innovations for emerging infectious diseases—a symposium report (2020) (13)
- Immunity to Haemophilus influenzae type b on sample population from central Italy. (1992) (13)
- Recent advances in meningococcal B disease prevention: real-world evidence from 4CMenB vaccination: Real-world effectiveness of MenB vaccination. (2021) (13)
- Inside sensors detecting outside pathogens (2004) (13)
- Cytoskeletal alterations as a parameter for assessment of toxicity. (1988) (13)
- Helicobacter pylori (2003) (13)
- In vitro selection of high affinity HspR-binding sites within the genome of Helicobacter pylori. (2002) (13)
- DNA sequence homology between attB-related sites of Corynebacterium diphtheriae, Corynebacterium ulcerans, Corynebacterium glutamicum, and the attP side of γ-Cornephage (1990) (13)
- 4CMenB Immunization Induces Serum Bactericidal Antibodies Against Non-Serogroup B Meningococcal Strains in Adolescents (2020) (13)
- The Escherichia coli heat‐labile enterotoxin induces apoptosis of immature lymphocytes in vivo via a glucocorticoid‐dependent pathway (2005) (13)
- Recombinant acellular pertussis vaccine--from the laboratory to the clinic: improving the quality of the immune response. (1992) (13)
- The pertussis toxin liberation genes of Bordetella pertussis are transcriptionally linked to the pertussis toxin operon (1996) (12)
- Aflunov®: a vaccine tailored for pre-pandemic and pandemic approaches against influenza (2013) (12)
- Novel vaccination strategies (2005) (12)
- Common Features of ADP—Ribosyltransferases (2000) (12)
- Deep Sequencing in Pre- and Clinical Vaccine Research (2013) (12)
- Ranking Vaccines: Applications of a Prioritization Software Tool: Phase III: Use Case Studies and Data Framework (2015) (12)
- Extremely potent human monoclonal antibodies from convalescent Covid-19 patients (2020) (11)
- Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin (2016) (11)
- New strategies for the prevention and treatment of Helicobacter pylori infection (2002) (11)
- Development and clinical testing of an acellular pertussis vaccine containing genetically detoxified pertussis toxin. (1992) (11)
- Delivering vaccines to the people who need them most (2015) (11)
- Towards a more comprehensive approach for a total economic assessment of vaccines? (2017) (11)
- H1N1: Can a Pandemic Cycle Be Broken? (2010) (11)
- Bridging the gap: need for a data repository to support vaccine prioritization efforts. (2015) (11)
- Molecular characterization H. pylori associated with cytotoxicity and duodenal ulcer (1993) (11)
- Vaccines as remedy for antimicrobial resistance and emerging infections. (2020) (11)
- Vision for a systems architecture to integrate and transform population health (2018) (11)
- Core values for vaccine evaluation. (2017) (11)
- Variability of genes encoding surface proteins used as vaccine antigens in meningococcal endemic and epidemic strain panels from Norway. (2014) (11)
- Improving membrane filtration processes (1995) (11)
- Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees (2022) (10)
- New vaccines against bacterial toxins. (1996) (10)
- Preventing Newborn Infection with Maternal Immunization (2013) (10)
- Looking beyond meningococcal B with the 4CMenB vaccine: the Neisseria effect (2021) (10)
- Meningococcal polysaccharide-protein conjugate vaccines (1997) (10)
- Chimeric Vaccines Against Japanese Encephalitis, Dengue, and West Nile (2004) (10)
- Studies of the antigenic structure of two cross-reacting proteins, pertussis and cholera toxins, using synthetic peptides. (1989) (10)
- Faculty Opinions recommendation of A beta-glucan-conjugate vaccine and anti-beta-glucan antibodies are effective against murine vaginal candidiasis as assessed by a novel in vivo imaging technique. (2011) (10)
- An unwanted guest: Neisseria meningitidis – carriage, risk for invasive disease and the impact of vaccination with insight on Italy incidence (2017) (10)
- Auto ADP‐ribosylation of NarE, a Neisseria meningitidis ADP‐ribosyltransferase, regulates its catalytic activities (2013) (9)
- Immunological fingerprint of 4CMenB recombinant antigens via protein microarray reveals key immunosignatures correlating with bactericidal activity (2020) (9)
- Mutant pertussis and Escherichia coli heat-labile toxins as adjuvants for enhancing local and systemic immune responses to coadministered, nonliving antigens (1997) (9)
- Influenza vaccines for the future (2008) (9)
- The Novartis Vaccines Institute for Global Health: a new initiative for developing vaccines for neglected diseases in developing countries. (2008) (9)
- Human monoclonal antibodies for discovery, therapy, and vaccine acceleration. (2019) (9)
- Meningococcus B: From Genome to Vaccine (2005) (9)
- Identification of an Iron-Sulfur Cluster That Modulates the Enzymatic Activity in NarE, a Neisseria meningitidis ADP-ribosyltransferase* (2009) (9)
- Biochemical and biological activities of recombinant S1 subunit of pertussis toxin (1990) (9)
- A C terminus cysteine of diphtheria toxin B chain involved in immunotoxin cell penetration and cytotoxicity. (1988) (9)
- Future Challenges for Vaccinologists (2015) (9)
- 2. How is the economic assessment of vaccines performed today? (2017) (9)
- Vaccines for the 21st century. A tool for decisionmaking (edited by KR Stratton, JS Durch and RS Lawrence) (2001) (9)
- 3. How comprehensive can we be in the economic assessment of vaccines? (2017) (9)
- Antigens from Neisseria meningitidis (1999) (9)
- COVID-19 mRNA third dose induces a unique hybrid immunity-like antibody response (2022) (9)
- Current approaches to developing a preventative HIV vaccine. (2005) (9)
- Meningococcal factor H-binding protein as immune evasion factor and vaccine antigen. (2020) (9)
- From microbial genomics to meta‐genomics (1997) (8)
- Toll-free immunity? (2008) (8)
- Improving accountability in vaccine decision-making (2017) (8)
- Will Systems Biology Deliver Its Promise and Contribute to the Development of New or Improved Vaccines? Systems Biology Views of Vaccine Innate and Adaptive Immunity. (2018) (8)
- Economic Analyses of Vaccines and Vaccination Programs (2004) (8)
- Changing route: aerosol vaccine against tuberculosis. (2014) (8)
- Vaccine Informatics (2011) (7)
- MOLECULAR GENETIC APPROACHES (1998) (7)
- Self-amplifying mRNA-Based Vaccine Technology and Its Mode of Action. (2021) (7)
- The respiratory syncytial virus (RSV) prefusion F‐protein functional antibody repertoire in adult healthy donors (2021) (7)
- Editorial overview: Vaccines: novel technologies for vaccine development. (2016) (7)
- Antibodies, epicenter of SARS-CoV-2 immunology (2021) (7)
- Compare voting systems to improve them (2017) (7)
- 66 – Technologies for Making New Vaccines (2018) (7)
- The Pangenome: A Data-Driven Discovery in Biology (2020) (7)
- Semisynthetic vaccines against bacterial meningitis (1991) (7)
- Generation of human monoclonal antibodies that confer protection against pertussis toxin (1992) (7)
- History of Diphtheria Vaccine Development (2014) (7)
- DNA sequence homology between attB-related sites of Corynebacterium diphtheriae, Corynebacterium ulcerans, Corynebacterium glutamicum, and the attP site of gamma-corynephage. (1990) (7)
- Antibody‐dependent macrophage‐mediated activity against Helicobacter pylori in the absence of complement (2002) (7)
- Hybrid immunity improves B cell frequency, antibody potency and breadth against SARS-CoV-2 and variants of concern (2021) (7)
- Blocking bacterial enterotoxins (2000) (7)
- Molecular epidemiology of nasopharyngeal corynebacteria in healthy adults from an area where diphtheria vaccination has been extensively practiced (1992) (7)
- Recombinant microbial ADP-ribosylating toxins of Bordetella pertussis, Vibrio cholerae, and enterotoxigenic Escherichia coli: structure, function, and toxoid vaccine development. (1994) (6)
- Meningococcal B Vaccine during a University Outbreak. (2016) (6)
- Novel molecular biology approaches to acellular vaccines. (1996) (6)
- Rationalizing the design of a broad coverage Shigella vaccine based on evaluation of immunological cross-reactivity among S. flexneri serotypes (2021) (6)
- Learning from the 2009 H1N1 pandemic: prospects for more broadly effective influenza vaccines. (2011) (6)
- Staphylococcus aureus coagulase R domain, a new evasion mechanism and vaccine target (2016) (6)
- Immune response to SARS-CoV-2 Omicron variant in patients and vaccinees following homologous and heterologous vaccinations (2022) (6)
- The nucleotide sequence of the gene coding for diphtheria toxoid CRM176. (1987) (6)
- CONVERSION FROM BORDETELLA PARAPERTUSSIS TO B PERTUSSIS (1987) (6)
- mRNA vaccines and hybrid immunity use different B cell germlines to neutralize Omicron BA.4 and BA.5 (2022) (6)
- Italy must invest more in science and technology (2008) (6)
- 60 – Technologies for making new vaccines (2013) (6)
- The trillion dollar vaccine gap (2022) (6)
- Erratum for Baddal et al., Dual RNA-seq of Nontypeable Haemophilus influenzae and Host Cell Transcriptomes Reveals Novel Insights into Host-Pathogen Cross Talk (2016) (6)
- Genome Mining and Reverse Vaccinology (2006) (6)
- Towards a vaccine against Escherichia coli-associated urinary tract infections. (2010) (6)
- [A phase-I clinical trial of a new antitetanus/antidiphtheria vaccine for adults]. (1991) (5)
- Neisseria gonorrhoeae PIII has a role on NG1873 outer membrane localization and is involved in bacterial adhesion to human cervical and urethral epithelial cells (2013) (5)
- Building an insurance against modern pandemics. (2010) (5)
- Vaccines research and development: poised for rapid growth (2007) (5)
- Timeline: Vaccines (2020) (5)
- DNA binding of the Bordetella pertussis H1 homolog alters in vitro DNA flexibility (1996) (5)
- NAP protein from helicobacter pylori (2002) (5)
- Correction: Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species (2011) (5)
- Virulent phenotypes associated with the cag pathogenicity island of Helicobacter pylori (1998) (5)
- Antibodies for Infectious Diseases (2015) (5)
- Finding epitopes with computers. (2013) (5)
- Action site and cellular effects of cytotoxin VacA produced byHelicobacter pylori (2008) (5)
- Characterisation of diverse sub-variants of the meningococcal factor H binding protein ( fHbp ) for their ability to bind fH , mediate serum resistance and induce bactericidal antibodies (2013) (5)
- Detection and physical map of a omega tox+-related defective prophage in Corynebacterium diphtheriae Belfanti 1030(-)tox- (1985) (5)
- Molecular approaches for safer and stronger vaccines. (1999) (5)
- Vaccines 2020: The era of the digital vaccine is here (2021) (5)
- Physicochemical characterisation of the pertussis vaccine. (2000) (5)
- A single intramuscular injection of monoclonal antibody MAD0004J08 induces in healthy adults SARS-CoV-2 neutralising antibody titres exceeding those induced by infection and vaccination (2021) (5)
- Safety and serum distribution of anti-SARS-CoV-2 monoclonal antibody MAD0004J08 after intramuscular injection (2022) (5)
- Production and characterization of high titre rabbit antigonococcal R-type lipopolysaccharide serum. (1982) (5)
- Vaccine Design in the 21st Century (2016) (4)
- An Overview of Biotechnology in Vaccine Development (2004) (4)
- A revised model of the active site of adp ribosylating toxins (1992) (4)
- Cellular Microbiology, Second Edition (2004) (4)
- Optimized fluorescent labeling to identify memory B cells specific for Neisseria meningitidis serogroup B vaccine antigens ex vivo (2013) (4)
- Immunology and Technology of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccines (2022) (4)
- Cost effectiveness has its place, but so does common sense (2014) (4)
- Genetic detoxification of bacterial toxins. (1996) (4)
- Pathogenesis of Helicobacter pylori and perspectives of vaccine development against an emerging pathogen. (1994) (4)
- Introduction: Addressing the challenge of group B streptococcal disease. (2013) (4)
- Genetic detoxification of bacterial toxins. (2003) (4)
- Microbial pathogenesis--an interdisciplinary point of view. (1995) (4)
- Helicobacter pylori vacuolating cytotoxin and neutrophil activating protein (2001) (4)
- Toxins as Vaccines and Adjuvants (2003) (4)
- 4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp (2020) (4)
- Models for bacterial infectious diseases: Helicobacter pylori (2004) (4)
- Faculty Opinions recommendation of DNA vaccine protection against SARS-CoV-2 in rhesus macaques. (2020) (4)
- Waiting for a pandemic (2008) (4)
- Vaccines, emerging viruses, and how to avoid disaster (2014) (4)
- Investigation on the Effect of Immune Selection on Resistance to Bactericidal Antibodies to Group B Meningococci In Vitro (2009) (4)
- Production of Large Quantities of Diphtheria Toxoid CRM45 (1985) (4)
- Determination of diphtheria toxin neutralizing antibody titers with a cell protein synthesis inhibition assay (2004) (4)
- Use of Pseudotyped Particles Expressing Influenza A/VietNam/1194/2004 Hemagglutinin in Neutralization Assays (2014) (4)
- Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19 (2022) (4)
- Editorial: Advanced Immunization Technologies for Next Generation Vaccines (2020) (4)
- Staphylococcal Protein A Induces Leukocyte Necrosis by Complexing with Human Immunoglobulins (2021) (4)
- The European effort towards the development of mucosal vaccines for poverty-related diseases. (2009) (4)
- Reverse Vaccinology: Revolutionizing the Approach to Vaccine Design (2006) (4)
- Long-term solutions for the problem of vaccine shortages (2004) (4)
- The challenges of vaccinating the very young: lessons from a very old system of host defense. (1999) (4)
- 8 – Att Sites, Tox Gene, and Insertion Elements as Tools for the Diagnosis and Molecular Epidemiology of Corynebacterium Diphtheriae (1990) (4)
- Further analysis of the sequence of the S1 subunit of pertussis toxin (1991) (3)
- Review 1: "BNT162b2 vaccine boosts neutralizing antibodies to ancestral SARS-CoV-2 & Omicron variant in adults received 2-dose inactivated vaccine" (2022) (3)
- Recent Progress in the Discovery and Development of Monoclonal Antibodies against Viral Infections (2022) (3)
- Towards animal free and science based measures of critical quality attributes for vaccine quality control and release. (2019) (3)
- The Mouse Model of Helicobacter Pylori Infection (1999) (3)
- Faculty Opinions recommendation of Programming self-organizing multicellular structures with synthetic cell-cell signaling. (2018) (3)
- Identification of a 35-Kilodalton Mycobacterium tuberculosis Protein Containing B- and T-Cell Epitopes (2006) (3)
- Escherichia coli, a Versatile Pathogen (2018) (3)
- Durable protection against SARS-CoV-2 Omicron induced by an adjuvanted subunit vaccine (2022) (3)
- Faculty Opinions recommendation of An mRNA Vaccine against SARS-CoV-2 - Preliminary Report. (2020) (3)
- Isolation and Characterization of Corynebacterium diphtheriae Nontandem Double Lysogens Hyperproducing CRM 197 (3)
- Adjuvant is necessary for a robust immune response to a single dose of H1N1 pandemic flu vaccine in mice. (2009) (3)
- Immune Responses to HPV 16 E7 (1994) (3)
- Targeting infectious diseases in the genomics era. (2006) (3)
- Anatomy of Omicron neutralizing antibodies in COVID-19 mRNA vaccinees (2022) (3)
- Improving influenza vaccines (2012) (3)
- GITR contributes to the systemic adjuvanticity of the Escherichia coli heat‐labile enterotoxin (2010) (3)
- Host-microbe interactions: bacteria - Microbiology will never be the same again ... Editorial overview (2001) (3)
- New Generation Vaccines, Fourth Edition (2004) (3)
- IS15 Developing vaccines in the era of genomics and toll receptors (2005) (3)
- Effects of the insertion of a nonapeptide from murine IL-1β on the immunogenicity of carrier proteins delivered by live attenuated Salmonella (1998) (3)
- Faculty Opinions recommendation of Diversity of the human intestinal microbial flora. (2005) (3)
- Beer promotes differentiation and mineralization of human osteoblastic cells: Role of silicon (2019) (3)
- Wild-type wine Saccharomyces cerevisiae as a tool to evaluate the effects on eukaryotic life of locally used herbicides (2006) (3)
- Faculty Opinions recommendation of The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine. (2011) (3)
- Abstract form for the Irish Journal of Medical Science v workshop on gastroduodenal pathology and Helicobacter pylori July 5th — 7th 1992 — Dublin, Ireland (1992) (3)
- The real cost of an affordable vaccine for meningococcus A (2003) (3)
- Non-viral delivery of self-amplifying RNA (2012) (3)
- Formaldehyde-treatment of Proteins Constrains Recognition by T Cells In Vitro But Not In Vivo (1993) (3)
- SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly (2022) (2)
- Development of vaccines at the time of COVID-19 (2020) (2)
- Current developments in new vaccines for adolescents. (1997) (2)
- Protective Efficacy Induced by Recombinant Clostridium difficile Toxin Fragments (2013) (2)
- Selective immunotoxins prepared with mutant diphtheria toxins coupled to monoclonal antibodies. (1989) (2)
- Faculty Opinions recommendation of Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization. (2005) (2)
- Faculty Opinions recommendation of Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals. (2020) (2)
- Foam formation and control in industrial fermentative production of modified diphtheria toxin by a mutant of Corynebacterium diphtheriae (1993) (2)
- Monoclonal Antibodies for Bacterial Pathogens: Mechanisms of Action and Engineering Approaches for Enhanced Effector Functions (2022) (2)
- Meningococcal diseases: From genomes to vaccines (2006) (2)
- Bacteriophages, a multi-tool to fight infectious disease. (2020) (2)
- INNAMORA, a European Workshop focussed on the mechanisms of innate immunity in pathogen–host interaction and their exploitation in novel mucosal immunisation strategies (2003) (2)
- B cell analyses after SARS-CoV-2 mRNA third vaccination reveals a hybrid immunity like antibody response (2023) (2)
- Toxin-Based Vaccines (Diphtheria, Tetanus, Pertussis) (1999) (2)
- cag, the Pathogenicity Island of Helicobacter pylori, Triggers Host Responses (1999) (2)
- Vaccination of Humans (2011) (2)
- Innovative vaccine approaches—a Keystone Symposia report (2022) (2)
- Pathogenicity island mediatesHelicobacter pylori interaction with the host (2008) (2)
- Editorial: A Global Perspective on Vaccines: Priorities, Challenges and Online Information (2019) (2)
- Four-component Meningococcal Serogroup B Vaccine Induces Antibodies With Bactericidal Activity Against Diverse Outbreak Strains in Adolescents. (2020) (2)
- The use and abuse of a 4-fold increase in antibody response to assess immunogenicity in early stage vaccine clinical trials. (2019) (2)
- Subunit Vaccines and Toxoids (2004) (2)
- Rediscovering complement, the first barrier of innate immunity. (2008) (2)
- 602 THE CANDIDATE HCV E1E2MF59 VACCINE IS SAFE IN CHRONIC HEPATITIS C PATIENTS AND ACCELLERATES THE SECOND PHASE VIRAL DECLINE UPON PRIMARY RESPONSE TO PEG-INTERFERON-2A/RIBAVIRIN THERAPY (2009) (2)
- Novel Immunologic Adjuvants (2011) (2)
- DNA Vaccination (2003) (2)
- Faculty Opinions recommendation of Mycobacterium tuberculosis produces pili during human infection. (2007) (2)
- Structural basis for immunization with post-fusion RSV F to elicit high neutralizing antibody titers (2011) (2)
- Difficulty in Developing a Neisserial Vaccine (2010) (2)
- Mechanisms of pathogenesis and prevention of meningococcal disease (2006) (2)
- Vaccines: ideal drugs for the 21st century? (2001) (2)
- NMR studies on the structure/function correlations of T-cell-epitope analogs from pertussis toxin. (1998) (2)
- Vaccine adjuvants: the future is bright (2013) (2)
- Helicobacter pylori: The Cancer Bug (2015) (2)
- Vaccination: Past, Present and Future (2005) (2)
- Reverse vaccinology and genomics : Genomic Medicine (2003) (2)
- Genome-based vaccine development: a short cut for the future. (2008) (2)
- New Generation Vaccines, 3rd Edition (2004) (2)
- Human T cell immunity against Bordetella pertussis analyzed at clonal level. (1991) (2)
- Pertussis ToxinPromoter Sequences Involved inModulation (1989) (1)
- Vaccine sprint predicted a decade ago (2021) (1)
- Faculty Opinions recommendation of The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria. (2004) (1)
- Identification of a 35-kilodalton Mycobacterium tuberculosis protein containing B- and T-cell epitopes (1990) (1)
- HP-NAP of Helicobacter pylori alters the coagulation-fibrinolysis balance of human blood mononuclear cells by stimulating the expression of Tissue Factor and PAI-2 (2001) (1)
- The origin of virulence in type I strains of Helicobacter pylori (1998) (1)
- Neisseria meningitidis population is structured in phylogenetic clades , associated with restriction-modification systems that modulate the effect of homologous recombination (2010) (1)
- Micro Correspondence (1992) (1)
- mRNA, the beginning of a new influenza vaccine game (2022) (1)
- Genetic approaches to a vaccine for pertussis. (1991) (1)
- Problems assaying neutrophil activators. (2001) (1)
- Reverse vaccinology: From genome to vaccine (2002) (1)
- Visualizing bacterial surfaces in real time (2009) (1)
- Inhibiting neuraminidase can make the difference (2019) (1)
- Pangenomic Reverse Vaccinology (2010) (1)
- Faculty Opinions recommendation of A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants. (2017) (1)
- Adjuvants and Subunit Vaccines (2010) (1)
- Neisseria gonorrhoeae PIII has a role on NG1873 outer membrane localization and is involved in bacterial adhesion to human cervical and urethral epithelial cells (2013) (1)
- CHAPTER 34 – Diphtheria (2011) (1)
- Development of a vaccine against serogroup B has been the main scientific challenge. Preface. (2012) (1)
- Challenges for Vaccinologists in the First Half of the Twenty-First Century. (2021) (1)
- Faculty Opinions recommendation of Multifaceted effects of antigen valency on B cell response composition and differentiation in vivo. (2020) (1)
- Vaccines in the Global Era (2022) (1)
- Public health perspective of a pentavalent meningococcal vaccine combining antigens of MenACWY-CRM and 4CMenB. (2022) (1)
- Faculty Opinions recommendation of Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. (2013) (1)
- Faculty of 1000 evaluation for Emergence of an Extensively Drug-Resistant Salmonella enterica Serovar Typhi Clone Harboring a Promiscuous Plasmid Encoding Resistance to Fluoroquinolones and Third-Generation Cephalosporins. (2018) (1)
- Faculty Opinions recommendation of Engineered human antibodies for the opsonization and killing of Staphylococcus aureus. (2022) (1)
- Vaccine Group B streptococcus (2003) (1)
- Molecular analysis of the Helicobacter pylori cytotoxin gene (1993) (1)
- juvenile rhesus monkeys. polysaccharide-protein conjugate vaccines in meningitidis and Escherichia coli K92 capsular Preclinical evaluation of group B Neisseria (2013) (1)
- Purification of gonococcal R-type lipopolysaccharide not bearing the lactose-like antigen. (1981) (1)
- Drugs and Vaccines Will Be Necessary to Control Tuberculosis (2020) (1)
- Novel approaches, including systems biology, to HIV vaccine research and development: Report from a Global HIV Vaccine Enterprise Working Group (2010) (1)
- Antimicrobial Resistance: A Tale of Nasty Enemies and Powerful Weapons (2020) (1)
- Seminars in Immunology. Technologies and opportunities for vaccines. Introduction. (2013) (1)
- Development of the new acellular recombinant pertussis vaccine. (1994) (1)
- Measurement of Neutralizing Antibody Responses to Influenza H5N1 Clade 1 A/Viet Nam/1194/04 and Clade 2 A/ Indonesia/5/05 Hemagglutinin Using a Sensitive High Throughput Luciferase- Based Retroviral Pseudotype Assay (2008) (1)
- The 130-kDa Vacuolating Cytotoxin-Associated Protein Is a Component of Cytotoxic Helicobacter pylori Organisms (1994) (1)
- Faculty Opinions recommendation of Use of genetic profiling in leprosy to discriminate clinical forms of the disease. (2003) (1)
- Metronidazole resistance in Helicobacter pylori. (1999) (1)
- Inhibition of the vacuolating and anion activities of the VacA of Helicobacter pylori. (1999) (1)
- Microbial Genomics: Targeted Antimicrobial Therapy and Genome Vaccines (2014) (1)
- Development of Vaccines for Ebola and Marburg Viruses: Efficacy and Regulatory Considerations (2009) (1)
- Immunisation against meningococcus B (2013) (1)
- A re-assessment of 4CMenB vaccine effectiveness against serogroup B invasive meningococcal disease in England based on an incidence model (2021) (1)
- Engineering bacterial toxin for the development of new vaccine against pertussis. (1988) (1)
- Infrared spectroscopy as a tool to determine the secondary structure of proteins and orientation of protein domains in lipid bilayers (1989) (1)
- Editorial overview: Preventive and therapeutic vaccines: Vaccination against viral disease — current advances and challenges (2017) (1)
- Safety and immunogenicity in animals of subunit influenza vaccine given intranasally with mutants of Escherichia coli heat-labile enterotoxin (LT) (2004) (1)
- What are affordable vaccines? (2015) (1)
- METRONIDAZOLE RESISTANCE IN HELICOBACTER PYLORI. AUTHORS' REPLY (1999) (1)
- 4.1. Helicobacter pylori: Pathogenic Determinants and Strategies for Vaccine Design (1996) (1)
- Hyaluronan derivatives: chemical modification and biochemical applications (2000) (1)
- Novel Strategies for Improved Vaccines for the Elderly: The Example of Influenza (2012) (1)
- Short-term and mid-term solutions for influenza vaccines. (2018) (1)
- Faculty Opinions recommendation of High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages. (2021) (1)
- Production of two SARS-CoV-2 neutralizing antibodies with different potencies in Nicotiana benthamiana (2022) (1)
- Committee on Identifying and Prioritizing New Preventive Vaccines for Development, Phase III (2013) (1)
- Comprar Influenza Vaccines for the Future | Rappuoli, Rino | 9783764383701 | Springer (2008) (1)
- 7.6 Molecular Genetics of Bordetella Pertussis Virulence (1998) (1)
- Faculty Opinions recommendation of Nanoparticle size influences antigen retention and presentation in lymph node follicles for humoral immunity. (2019) (1)
- Vaccines, emerging viruses, and how to avoid disaster (2014) (1)
- Reverse Vaccinology , and Bacterial Pathogenesis (2013) (1)
- Introduction: Helicobacter pylori, from witchcraft to drugs to vaccines (2003) (1)
- Pertussis toxin mutants, the same producing Bordetella strains and their use as a vaccine against pertussis. (1990) (0)
- Use of pseudotyped particles expressing influenza A/Viet Nam/1194/2004 haemagglutinin in immunological assays (2007) (0)
- Optimizing Response to Vaccination in the Elderly (2014) (0)
- Faculty Opinions recommendation of Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes. (2004) (0)
- Development and Clinical Results with an Acellular Vaccine Containing Genetically Detoxified Pertussis Toxin (1993) (0)
- Antigenic peptides of Neisseria (2000) (0)
- Vaccine candidates for poor nations are going to waste (2018) (0)
- Monack Persistent Infection Strategies Salmonella and Helicobacter (2013) (0)
- Faculty Opinions recommendation of Expression of Th1-mediated immunity in mouse lungs induces a Mycobacterium tuberculosis transcription pattern characteristic of nonreplicating persistence. (2003) (0)
- Transcription Repressor and as an Activator of Gene , Acting both as a Neisseria meningitidis of CrgA Is an Inducible LysR-Type Regulator (2005) (0)
- Presentations at the UK National Immunisation Conference (2022) (0)
- Antigenes de neisseria conserves (2000) (0)
- 2D NMR Analysis as a Sensitive Tool for Evaluating the Higher-Order Structural Integrity of Monoclonal Antibody against COVID-19 (2022) (0)
- The candidate HCV E1E2MF59 vaccine enhances 2nd phase viral decline in responders to PEG-IFN/ribavirin (2009) (0)
- Faculty Opinions recommendation of TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease. (2018) (0)
- PROTEIN CONFORMATION AFFECTS THE EFFICACY OF PERTUSSIS VACCINES (1991) (0)
- Use Case Scenarios and Design Enhancements (2015) (0)
- Faculty Opinions recommendation of Designed protein logic to target cells with precise combinations of surface antigens. (2020) (0)
- Faculty Opinions recommendation of Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers. (2019) (0)
- STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE (2010) (0)
- The small GTP binding protein rab 7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin C-terminal domain and released into the extracellular (2013) (0)
- Faculty Opinions recommendation of Structure of a patient-derived antibody in complex with allergen reveals simultaneous conventional and superantigen-like recognition. (2018) (0)
- Faculty Opinions recommendation of Cutting edge: long-term B cell memory in humans after smallpox vaccination. (2003) (0)
- Toxin into vaccine: studies of AB5 bacterial toxins (1996) (0)
- Faculty Opinions recommendation of Hydrogel delivery of lysostaphin eliminates orthopedic implant infection by Staphylococcus aureus and supports fracture healing. (2018) (0)
- Crystal structure of group B Streptococcus type III DP2 oligosaccharide bound to Fab NVS-1-19-5 (2017) (0)
- Pertactin antigens extracted from Bordetella pertussis and Bordetella bronchiseptica differ in the isoelectric point (1997) (0)
- Faculty Opinions recommendation of CCR5 is a receptor for Staphylococcus aureus leukotoxin ED. (2013) (0)
- Microbial Vaccine Design: The Reverse Vaccinology Approach (2011) (0)
- Vaccination with multiple clades of influenza virus A H5 (2008) (0)
- Culture medium with soybean extract protein complex as amino acids-source and without animal origin (1998) (0)
- OMV vaccine supplemented against meningococcus (2001) (0)
- Faculty Opinions recommendation of Down-regulation of pili and capsule of Neisseria meningitidis upon contact with epithelial cells is mediated by CrgA regulatory protein. (2002) (0)
- A strategic model for developing vaccines against neglected diseases: An example of industry collaboration for sustainable development (2022) (0)
- ADP-ribosilant bacterial toxins (2002) (0)
- Faculty Opinions recommendation of Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4. (2018) (0)
- Faculty Opinions recommendation of Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. (2003) (0)
- DNA VACCINE ADMINISTRATION BY INTRAMUSCULAR INJECTION OF THE QUADRICPEPS MUSCLES IN THE MOUSE (2003) (0)
- On the Cellular Mechanism of Action of Diphtheria Toxin (1989) (0)
- Faculty Opinions recommendation of Prevention of tuberculosis in macaques after intravenous BCG immunization. (2020) (0)
- Improve the bactericidal activity of neisseria antigens containing oligonucleotides with cg (2000) (0)
- Faculty Opinions recommendation of Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys. (2013) (0)
- A vision of immuno-oncology: the Siena think tank of the Italian network for tumor biotherapy (NIBIT) foundation (2021) (0)
- Chapter 2 Future Challenges for Vaccinologists (2018) (0)
- An abundance of bacterial ADP-ribosyltransferases – implications for the origin of exotoxins and their human homologues (2001) (0)
- Faculty Opinions recommendation of Metagenomic sequencing at the epicenter of the Nigeria 2018 Lassa fever outbreak. (2019) (0)
- With the cytotoxin of helicobacter pylori associated, immunodominant antigen used in vaccines and to diagnose (1993) (0)
- Allelic variation in the vacA gene of Helicobacter pylori isolated from China (2000) (0)
- Neisserial antigen peptides (2000) (0)
- [Genome and infectious diseases]. (2005) (0)
- Vaccination and autoimmunity (2004) (0)
- Introduction to the vaccine supplement. (2017) (0)
- Save the microbes to save the planet. A call to action of the International Union of the Microbiological Societies (IUMS) (2023) (0)
- A process for preparing an immunogenic factor of Corynebacterium diphtheriae using a culture medium with yeast extract as a source of amino acids and without protein complexes of animal origin (1998) (0)
- Production and characterization of monoclonal antibodies (Mabs) specifically reactive with the different subunits of toxin from "Bordetella pertussis". (1986) (0)
- Neisseria meningitidis protein (1999) (0)
- Faculty Opinions recommendation of AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. (2006) (0)
- 827 EXPERIMENTAL HCV VACCINE COMBINING ADENOVIRUS AND PROTEIN ELICITS POTENT T-CELL RESPONSES AND NEUTRALIZING ANTIBODIES IN RODENTS (2012) (0)
- Data Sources and Methodology for SMART Vaccines (2013) (0)
- Historical Advances in Structural and Molecular Biology and How They Impacted Vaccine Development (2023) (0)
- Faculty Opinions recommendation of Structure of the ecto-ADP-ribosyl transferase ART2.2 from rat. (2003) (0)
- Faculty Opinions recommendation of A protective Zika virus E-dimer-based subunit vaccine engineered to abrogate antibody-dependent enhancement of dengue infection. (2019) (0)
- Bumpy Road to Vaccination Policies (2007) (0)
- Positive transcriptional feedback at the bvg locus controls expression of virulence factors in Bordetella pertussis. (1990) (0)
- Preparation for nasal administration containing vibrio cholera zonula occludins toxin absorption as mediator (1998) (0)
- Neisseria meningitidis antigenic and compositions (1999) (0)
- Faculty Opinions recommendation of A human apolipoprotein L with detergent-like activity kills intracellular pathogens. (2021) (0)
- Faculty Opinions recommendation of Reconstitution of pilus assembly reveals a bacterial outer membrane catalyst. (2008) (0)
- An immunogenic detoxified mutant E. coli LT-A toxin (1997) (0)
- Faculty Opinions recommendation of Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm. (2018) (0)
- Lung Infectious Disease ( LTK 63 ) Provides Generic Protection against Escherichia coli Heat-Labile Toxin of Innate Imprinting by the Modified and Tracy (2004) (0)
- European Workshop on Bacterial Protein Toxins (4th) Held in Urbino, Italy on July 3-6, 1989 (1990) (0)
- Faculty Opinions recommendation of Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. (2002) (0)
- Science Translational Medicine Podcast: 13 July 2011 (2011) (0)
- LIPOTEICHOIC ACID AND FLAGELLIN INDUCE UP-REGULATION OF ART1 INAIRWAY EPITHELIAL CELLS (2005) (0)
- 37 – Vaccine Development (2002) (0)
- Different electron microscopical approaches to study pilus-like structures in Streptococci during infection (2011) (0)
- Thanks to Reviewers and Sources of Submissions (2017) (0)
- Immunogenic, non-toxic mutant of the toxin LT from E. coli a (1997) (0)
- Faculty Opinions recommendation of Microbial factor-mediated development in a host-bacterial mutualism. (2004) (0)
- "Vaccines Against Meningococcus" An update of the progresses in meningitis prevention, based on the Meningococcus Scientific Exchange Meeting, Siena, Italy, 1-3 July 2008. (2009) (0)
- Rapid generation of Shigella flexneri GMMA displaying natural or new and cross-reactive O-Antigens (2022) (0)
- Disease Eradication by Vaccination (2015) (0)
- Faculty Opinions recommendation of Peptidoglycan crosslinking relaxation promotes Helicobacter pylori's helical shape and stomach colonization. (2010) (0)
- Fiber hemagglutinin of b. pertussis (1989) (0)
- Composition for nasal administration containing vibrio cholera toxin zonula occludens as absorption enhancer. (1998) (0)
- Enterotoxin-Based Mucosal Adjuvants Lymphocyte Responses Induced by MHC Class I-Restricted Cytotoxic (1999) (0)
- Engineering bacterial toxins for the development of a new vaccine against whooping cough. (1989) (0)
- Genomic neisseriasekvenser and progress ways of use thereof (2000) (0)
- Faculty Opinions recommendation of Infection, inflammation, height, and longevity. (2006) (0)
- Faculty Opinions recommendation of A mouse model of Salmonella typhi infection. (2013) (0)
- Neisseria genomic sequences and methods of use. (2000) (0)
- Faculty Opinions recommendation of Intracellular bacterial biofilm-like pods in urinary tract infections. (2003) (0)
- Deep Sequencing in Vaccine Research, Development and Post-marketing Surveillance (2015) (0)
- Vaccines for the future. (1971) (0)
- Recombinant Protein Antigens with ‘Built-in’ Adjuvanticity (1993) (0)
- Vaccination (new adjuvants etc.) (SY5-3) Chairpersons: Hiroshi Kiyono, Rino Rappuoli (2010) (0)
- Faculty Opinions recommendation of Genome-wide screen identifies curli amyloid fibril as a bacterial component promoting host neurodegeneration. (2021) (0)
- mRNA vaccines and hybrid immunity use different B cell germlines against Omicron BA.4 and BA.5 (2023) (0)
- Editorial overview: Vaccines 2020 (2020) (0)
- Vaccines for a sustainable planet (2023) (0)
- Faculty Opinions recommendation of Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function. (2008) (0)
- Data Synthesis, Software Redesign, and Evaluation (2013) (0)
- A new and safer pertussis vaccine is on the way (1990) (0)
- DNA Binding of theBordetella pertussisH1 Homolog Alters In (1996) (0)
- Reviews of "BNT162b2 vaccine boosts neutralizing antibodies to ancestral SARS-CoV-2 & Omicron variant in adults received 2-dose inactivated vaccine" (2022) (0)
- Faculty Opinions recommendation of External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers. (2010) (0)
- Pharmaceutical biotechnology (2003) (0)
- Neisseria meningitidis serogroups compositions b and c-antigenic and containing an additional antigen (2000) (0)
- Editorial overview: Vaccines (2022) (0)
- 6 – DISEASE STATES AND VACCINES: SELECTED CASES: PART K. Helicobacter Pylori (2003) (0)
- Absolute Quantification of the Bexsero Vaccine Component Factor H Binding Protein (fHbp) by Selected Reaction Monitoring: The Contribution of Mass Spectrometry in Vaccinology (2016) (0)
- Faculty Opinions recommendation of Inborn errors of type I IFN immunity in patients with life-threatening COVID-19. (2020) (0)
- Faculty Opinions recommendation of How to become a uropathogen: comparative genomic analysis of extraintestinal pathogenic Escherichia coli strains. (2006) (0)
- Faculty Opinions recommendation of Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor. (2007) (0)
- Faculty Opinions recommendation of Interactions with fibronectin attenuate the virulence of Streptococcus pyogenes. (2004) (0)
- Eurotox‐6 Conference: old bacterial toxins reveal new cell machineries (1994) (0)
- Faculty Opinions recommendation of Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. (2009) (0)
- IL-10-Dependent Mechanisms throughInduces Th 1 / Th 17 Immune Response Genetically Detoxified Pertussis Toxin (2009) (0)
- Faculty Opinions recommendation of Optimizing the impact of low-efficacy influenza vaccines. (2018) (0)
- Vaccines: a health insurance of the 21st century (2011) (0)
- Introduction: SMART Vaccines and Smart Priorities (2015) (0)
- Genomics and Proteomics in Vaccine Design (2003) (0)
- Human T-cell immunity against Bordetella pertussis analyzed at clonal level. (1988) (0)
- Infections Escherichia coli In Vitro and In Vivo Model Systems for Studying Enteropathogenic (2013) (0)
- Identification of non-LPS bacterial ligands for the class A macrophage scavenger receptor on Neisseria meningitidis using a novel assay (2005) (0)
- A recombinant DNA approach to the pertussis vaccine. (1986) (0)
- Learning from the First Pandemic of the Twenty-First Century (2011) (0)
- Subject Index Vol. 108, 1995 (1995) (0)
- CHAPTER 49 – Vaccines Against Infectious Diseases: A Biotechnology-Driven Evolution (2009) (0)
- Reflections and Looking Forward (2015) (0)
- Improved vesicles of the outer membrane of the bacteria (2003) (0)
- Functional ap.alysis of the pcrtussis toxin promoter (1992) (0)
- Faculty Opinions recommendation of Passive immunization with neutralizing antibodies interrupts the mouse mammary tumor virus life cycle. (2003) (0)
- Observations and Looking Forward (2013) (0)
- A NOVEL NAD:ARGININE:ADP-RIBOSYLTRANSFERASE FROM NEISSERIA MENINGITIDIS (2001) (0)
- Faculty Opinions recommendation of De novo protein design by citizen scientists. (2019) (0)
- Human T-cell Immunity against Bordetella pertussis Analyzed at Clonal Level(II. Molecular Biological and Genetic Analysis of Bordetella pertussis)(Current Studies on Future Vaccines) (1988) (0)
- Faculty Opinions recommendation of Cholera toxin promotes pathogen acquisition of host-derived nutrients. (2019) (0)
- Committee's Response to the Use Case Scenarios Report (2015) (0)
- Faculty Opinions recommendation of Regulation of phagosome maturation by signals from toll-like receptors. (2004) (0)
- Antibody to Neisseria meningitidis A Novel Mimetic Antigen Eliciting Protective (2013) (0)
- A process for the immunization against and treatment of infections caused by H.pylori (1999) (0)
- Toxin lt e-a. coli mutant detoxified immunogenic. (1997) (0)
- Faculty Opinions recommendation of Pathogen elimination by probiotic Bacillus via signalling interference. (2018) (0)
- Adjuvanticity of a mutant of heat-labile enterotoxin of E. coli for the induction of measles specific CTL responses after intranasal coimmunization with a synthetic peptide (1997) (0)
- Faculty Opinions recommendation of A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity. (2021) (0)
- Advanced vaccine research : methods for the decade of vaccines (2015) (0)
- Faculty Opinions recommendation of GROWTH POLE RING protein forms a 200-nm-diameter ring structure essential for polar growth and rod shape in Agrobacterium tumefaciens. (2019) (0)
- alphavirus replicon particle-based influenza vaccine by pre- (2012) (0)
- Culture medium with soybean extract as a source of amino acids but without animal protein complexes. (1998) (0)
- MOLECULAR CHARACTERISATION OF A NOVEL ADP-RIBOSYLATING PUTATIVE TOXIN OF NEISSERIA MENINGITIDIS (2002) (0)
- Faculty Opinions recommendation of Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity. (2020) (0)
- Faculty Opinions recommendation of Maintenance of serological memory by polyclonal activation of human memory B cells. (2003) (0)
- Antigens and Neisseria meningitidis compositions. (1999) (0)
- New-age vaccine adjuvants, their development, and future perspective (2023) (0)
- Conjugates of heat hock proteins and oligo- or polysaccharides (1993) (0)
- Allelic variation in the vacA gene of Helicobacter pylori isolated from Chinese patients (2001) (0)
- The adjuvant action of pertussis toxin for Th1 and Th2 responses is associated with enhanced co-stimulatory molecule expression and regulatory cytokine production (1997) (0)
- The neutralizing response to SARS-CoV-2 Omicron variants BA.1 and BA.2 in COVID-19 patients and homologous and heterologous vaccinees (2022) (0)
- Microbial Genomics and Global Health (2012) (0)
- Compositions combinations Neisseria (2000) (0)
- Faculty Opinions recommendation of Auto-antibodies against type I IFNs in patients with life-threatening COVID-19. (2020) (0)
- New pertussis toxin variant, bordetella bacterial strain capable of producing such variant and its use in development of pertussis vaccine (1996) (0)
- Faculty Opinions recommendation of Follicular regulatory T cells produce neuritin to regulate B cells. (0)
- Refinements to the SMART Vaccines Model (2013) (0)
- Detoxified immunogenic mutant cholera toxins. (1996) (0)
- A process for the culture of microorganisms of the genus Helicobacter, Campylobacter and Arcobacter using cyclodextrins or methylcellulose, or mixtures containing culture media (1992) (0)
- Toxins and toxoids as mucosal immunogens and adjuvants (1996) (0)
- Faculty Opinions recommendation of A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin. (2004) (0)
- Jean-Marc Reyrat (29/04/1967–28/10/2009) (2010) (0)
- Chronically Infected Promonocytic U1 Cells Macrophages and Virus Expression in Inhibits HIV Replication in Human The Binding Subunit of Pertussis Toxin (2001) (0)
- Faculty Opinions recommendation of Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection. (2015) (0)
- Meningococcal Vaccines: A Technological Revolution (2021) (0)
- Immunogenic, nontoxic cholera toxin mutant (1996) (0)
- Contents, Vol. 108, 1995 (1995) (0)
- Vaccinology – Editorial (2020) (0)
- Faculty Opinions recommendation of SARS-CoV-2 infection protects against rechallenge in rhesus macaques. (2020) (0)
- Faculty Opinions recommendation of Signal sequence directs localized secretion of bacterial surface proteins. (2006) (0)
- Faculty Opinions recommendation of A bacterial effector acts as a plant transcription factor and induces a cell size regulator. (2007) (0)
- Nhieu Invasion of Intestinal Epithelial Cells Shigella The Inside Story of (2013) (0)
- Recombinant DNA vaccines: Rationale and strategy: edited by R.E. Isaacson Marcel Dekker, 1992. $145.00/£72.70 (409 pages) ISBN 0 8247 8699 8 (1993) (0)
- Enzyme Activity Effects of the Nontoxic AB Complex and the Toxin : Distinct Pro-and Anti-Inflammatory Heat-Labile Escherichia coli Responses by Modulation of Innate and Acquired Immune Rappuoli (2000) (0)
- Human papillomavirus E2 protein: a potential key regulator of viral cell pathogenesis (2012) (0)
- Faculty Opinions recommendation of The challenge of antimicrobial resistance: What economics can contribute. (2019) (0)
- Neisseriale antigenic peptides. (2000) (0)
- Classical- and bioconjugate vaccines: comparison of the structural properties and immunological response. (2022) (0)
- Faculty Opinions recommendation of A durable protective immune response to wild-type measles virus infection of macaques is due to viral replication and spread in lymphoid tissues. (2020) (0)
- Bacterial outer membrane vesicles improved (2003) (0)
- Approaches to Target Conserved Conformational Epitopes in HIV Envelope (2005) (0)
- Faculty Opinions recommendation of A monoclonal antibody for malaria prevention. (2021) (0)
- Genomics of ecology and industrial microbiology. (2009) (0)
- Editorial: Intersection of biophysical and structural approaches in vaccine design (2023) (0)
- Faculty Opinions recommendation of Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. (2006) (0)
- Faculty Opinions recommendation of Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori. (2003) (0)
- Faculty Opinions recommendation of A neuronal isoform of the aplysia CPEB has prion-like properties. (2004) (0)
- Introduction: New Vaccines and SMART Vaccines (2013) (0)
- Candidate Disease Profiles (2013) (0)
- Persistence in Response to Vaccination Germinal Center B Cell Differentiation and Oil-in-Water Emulsion MF59 Increases (2015) (0)
- Looking beyond meningococcal B with the 4CMenB vaccine: the Neisseria effect (2021) (0)
- Verification and Analyses of the SMART Vaccines Computational Model (2013) (0)
- Supplementary Material 14 (2015) (0)
- Faculty Opinions recommendation of Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation. (2018) (0)
- Dawn of the Postantibiotic Era Bacterial Biofilms: Development, Dispersal, and Therapeutic Strategies in the (2014) (0)
- Disease Eradication by Vaccination: Prospects (2007) (0)
- Faculty Opinions recommendation of EsaC substrate for the ESAT-6 secretion pathway and its role in persistent infections of Staphylococcus aureus. (2008) (0)
- Immunogenic composition comprising a SARS coronavirus spicular protein (2004) (0)
- Low Inhibition Systems Mechanisms and Biological Roles of Contact-Dependent Growth (2014) (0)
- Helicobacter pylori cytotoxin used in vaccines and diagnostics (1993) (0)
- MAPKs and IL-10-Dependent Mechanismsthrough Induces Th1/Th17 Immune Response Genetically Detoxified Pertussis Toxin (2009) (0)
- Solution structure of the antigenic domain of GNA1870 of Neisseria meningitidis (2006) (0)
- Interaction of diphtheria toxin (fragment B) with natural membranes (1987) (0)
- Faculty Opinions recommendation of A proof of concept for structure-based vaccine design targeting RSV in humans. (2019) (0)
- The nucleotide sequence of the gene coding toxoid CRM176 (1987) (0)
- Mutation Infection Bacterial multiplication Bacterial multiplication Antibiotic sensitive bacteria Antibiotic resistant bacteria Infection No vaccine pressure in the environment Antibiotics Vaccine (2012) (0)
- Part L - Genome-Based Approach for a Vaccine against Neisseria meningitidis (2003) (0)
- | New Generation Vaccines | Taylor & Francis Group (2004) (0)
- Problems in identifying microbial-derived neutrophil activators, focusing on Helicobacter pylori (2002) (0)
- Faculty Opinions recommendation of Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition. (2018) (0)
- Heat-Labile Enterotoxin Escherichia coli and Mutants of Neisseria meningitidis Intranasal Immunization with NadA of Antibodies and Cellular Immunity following Meningococci : Induction of Bactericidal Mucosal Vaccination against Serogroup B (2004) (0)
- Computational Modeling for SMART Vaccines (2013) (0)
- Faculty Opinions recommendation of Staphylococcus aureus degrades neutrophil extracellular traps to promote immune cell death. (2014) (0)
- Flu vaccines that include combinations of particulate adjuvants and immunopotentiating (2006) (0)
- Neisseria meningitidis antigenic and assortments (1999) (0)
- Antibodies, epicenter of SARS-CoV-2 immunology (2021) (0)
- Neisseria antigens and preparations (1999) (0)
- Antibody Immune Responses Regimen Elicits T Cell and Neutralizing C Virus Envelope Protein Prime-Boost Combined Adenovirus Vector and Hepatitis (2014) (0)
- Faculty Opinions recommendation of Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β. (2012) (0)
- Faculty Opinions recommendation of The role of neutralizing antibodies for mouse mammary tumor virus transmission and mammary cancer development. (2003) (0)
- Faculty Opinions recommendation of West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H. (2007) (0)
- Profiling Vaccines for an Immunosenescent and Multimorbid Population (2019) (0)
- HELICOBACTER PYLORI VACUOLATING TOXIN INDUCES Ca2+-MEDIATED Cl--SECRETION IN CACO-2 CELLS. (1997) (0)
- Faculty Opinions recommendation of Clonal integration of a polyomavirus in human Merkel cell carcinoma. (2008) (0)
- Faculty Opinions recommendation of Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance. (2019) (0)
- DISEASE STATES AND VACCINES: SELECTED CASES (2003) (0)
- Faculty Opinions recommendation of Acquisition of virulence genes by a carrier strain gave rise to the ongoing epidemics of meningococcal disease in West Africa. (2018) (0)
- Faculty of 1000 evaluation for The impact of past vaccination coverage and immunity on pertussis resurgence. (2018) (0)
- Faculty Opinions recommendation of Inducible antibacterial defense system in C. elegans. (2002) (0)
- Faculty Opinions recommendation of Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells. (2019) (0)
- HIV-1 Tat binds Env forming a virus entry complex which enhances HIV infectivity and targets the virus to RGD-binding integrins (2008) (0)
- Faculty Opinions recommendation of Toll-like receptor 9 inhibition reduces mortality in polymicrobial sepsis. (2008) (0)
- Tat cd4-hiv-hybrid molecules and use procedures for (2006) (0)
- Supplementary Material 13 (2014) (0)
- Echinococcosis, Ningxia, China (2019) (0)
- Corrigendum: Vaccines Against Antimicrobial Resistance (2020) (0)
- Advancing Vaccines in the Genomics Era (0)
- Novel Vaccine Candidate of Neisseria meningitidis (2002) (0)
- MONO ADP-RIBOSYLATION ON THE SURFACE OF PULMONARY EPITHELIAL CELLS (2003) (0)
- MONO ADP-RIBOSYLTRANSFERASES EXPRESSED ON THE SURFACE OF PULMONARY EPITHELIAL CELLS ARE REGULATED BY PATHOGEN-ASSOCIATED MOLECULAR PATTERNS (2007) (0)
- Antigenic recognition of pertussis and cholera toxin by the same antipeptide antibodies. (1986) (0)
- Faculty Opinions recommendation of An in vivo gene deletion system for determining temporal requirement of bacterial virulence factors. (2008) (0)
- Bacterial protein toxins : fourth European workshop, Urbino, July 3-July 6, 1989 (1990) (0)
- Faculty Opinions recommendation of Identification of a structural motif crucial for infectivity of hepatitis B viruses. (2006) (0)
- Faculty Opinions recommendation of Type I interferon production enhances susceptibility to Listeria monocytogenes infection. (2004) (0)
- AN IRON-SULFUR CLUSTER IN NARE MODULATES ITS ENZYMATIC ACTIVITIES (2009) (0)
- 7. Two-Dose 4CMenB Vaccination in Adolescents Elicits a Bactericidal Activity against 15 Outbreak-Representative Meningococcal Strains (2020) (0)
- Human T lymphocyte clones specific for "Bordetella pertussis". (1986) (0)
- Faculty Opinions recommendation of Resurgence of Vaccine-Preventable Diseases in Venezuela as a Regional Public Health Threat in the Americas. (2019) (0)
- Safety and serum distribution of anti-SARS-CoV-2 monoclonal antibody MAD0004J08 after intramuscular injection (2022) (0)
- Immunogenicity of an acellular pertussis vaccine composed of genetically inactivated pertussis toxin combined with FHA and pertactin in infants and children (1993) (0)
- From pioneers to marketeers (2000) (0)
- Detoxified mutant bacterial adp ribosylierender toxins as parenteral adjuvants (1998) (0)
- The Microbial Pangenome: Implications for Vaccine Development (2011) (0)
- Faculty Opinions recommendation of Induction of potent neutralizing antibody responses by a designed protein nanoparticle vaccine for respiratory syncytial virus. (2019) (0)
- Compositions comprising Neisseria antigens from serogroups miningitidis byc well as other antigen. (2000) (0)
- neutralizing antibodies. native conformation for induction of Helicobacter pylori cytotoxin: importance of (2013) (0)
- from peripheral blood and gastric biopsies. Helicobacter pylori-specific CD4+ T-cell clones (2013) (0)
- Faculty Opinions recommendation of Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates. (2009) (0)
- Influenza vaccines containing combinations of particulate adjuvants, and immune enhancers (2006) (0)
- Membrane vesicles (OMV) vaccine, the n. Meningitidis serogroup B membrane proteins containing (2001) (0)
- Rational Design of Vaccine Molecules to Prevent Pertussis (1995) (0)
- A carrier protein polyepitope (1999) (0)
- F 270 ROLE OF HELICOBACTER PYLORI SEROLOGjY IN SCREENING PRIOR TO DIRECT ACCESS ENDOSCOPY (2006) (0)
- Faculty Opinions recommendation of Regulatory T cells enhance persistence of the zoonotic pathogen Seoul virus in its reservoir host. (2007) (0)
- Cell trafficking alterations caused by the H. pylori VacA toxin (2000) (0)
- Current Topics in Microbiology and Immunology (1976) (0)
- Faculty Opinions recommendation of Dengue type 1 viruses circulating in humans are highly infectious and poorly neutralized by human antibodies. (2019) (0)
- Faculty Opinions recommendation of Neutrophil extracellular traps kill bacteria. (2004) (0)
- A new biomaterial more resistent to infection to be used to manufacture biliary endoprostheses (1998) (0)
- Introduction to the supplement. (2015) (0)
- K01.1 Bacterial STI vaccines – eternal dream or future reality? (2019) (0)
- Human protective response induced by meningococcus B vaccine is mediated by the synergy of multiple bactericidal epitopes (2018) (0)
- Emerging roles of SARS-CoV-2 Spike-ACE2 in immune evasion and pathogenesis (2023) (0)
- Experimental model of Helicobacter pylori infection. (1998) (0)
- of heat-labile enterotoxin. derivatives and protease sensitivity of nontoxic Mutations in the A subunit affect yield, stability, (2013) (0)
- Efficacy of Vaccination with Different Combinations of MF59-Adjuvanted and Nonadjuvanted Seasonal and Pandemic Influenza Vaccines against Pandemic H1N1 (2009) Influenza Virus Infection in Ferrets (cid:1) (2011) (0)
- Polypeptides for oligomeric antigen assembly. (2005) (0)
- THE ADP-RIBOSYLTRANSFERASE FROM NEISSERIA MENINGITIDIS DISPLAYS AUTO-ADP-RIBOSYLATION ACTIVITY (2002) (0)
- A new dawn for monoclonal antibodies against antimicrobial resistant bacteria (2022) (0)
- Immunoreactive polypeptide and its production (1988) (0)
- Faculty Opinions recommendation of A double-blind randomized placebo-controlled phase III study of a Pseudomonas aeruginosa flagella vaccine in cystic fibrosis patients. (2007) (0)
- Mucosal vaccines DTPA. (2000) (0)
- In This Issue (2003) (0)
- Bacterial protein toxins. Eighth European Workshop, Staffelstein, Kloster Banz, Germany, June 29 to July 04, 1997. (1998) (0)
- Faculty Opinions recommendation of Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles. (2019) (0)
- Data Synthesis and Framework (2015) (0)
- VACCINES: OUR INSURANCE FOR A HEALTHIER LIVING (2010) (0)
- Faculty Opinions recommendation of Translocation of YopE and YopN into eukaryotic cells by Yersinia pestis yopN, tyeA, sycN, yscB and lcrG deletion mutants measured using a phosphorylatable peptide tag and phosphospecific antibodies. (2003) (0)
- Faculty Opinions recommendation of Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans. (2019) (0)
- Recombinant BCG Expressing LTAK63 Adjuvant induces Superior Protection against Mycobacterium tuberculosis (2017) (0)
This paper list is powered by the following services:
Other Resources About Rino Rappuoli
What Schools Are Affiliated With Rino Rappuoli?
Rino Rappuoli is affiliated with the following schools:
