R. J. Johnson
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(Suggest an Edit or Addition)R. J. Johnson's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Renal injury from angiotensin II-mediated hypertension. (1992) (555)
- Membranoproliferative glomerulonephritis associated with hepatitis C virus infection responsive to interferon-alpha. (1993) (535)
- Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation. (1991) (475)
- Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model. (1992) (430)
- Mesangial cell apoptosis: the major mechanism for resolution of glomerular hypercellularity in experimental mesangial proliferative nephritis. (1994) (424)
- Impaired angiogenesis in the remnant kidney model: I. Potential role of vascular endothelial growth factor and thrombospondin-1. (2001) (412)
- Impaired angiogenesis in the remnant kidney model: II. Vascular endothelial growth factor administration reduces renal fibrosis and stabilizes renal function. (2001) (407)
- Evidence for a role of osteopontin in macrophage infiltration in response to pathological stimuli in vivo. (1998) (399)
- Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor (1992) (359)
- Cellular events in the evolution of experimental diabetic nephropathy. (1995) (334)
- Risk factors and mortality associated with calciphylaxis in end-stage renal disease. (2001) (320)
- Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture. (1994) (293)
- Obstructive uropathy in the mouse: role of osteopontin in interstitial fibrosis and apoptosis. (1999) (290)
- Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6-nephrectomized rats. (1996) (280)
- Increased synthesis of extracellular matrix in mesangial proliferative nephritis. (1991) (276)
- Enhanced expression of "muscle-specific" actin in glomerulonephritis. (1992) (273)
- Impaired angiogenesis in the aging kidney: vascular endothelial growth factor and thrombospondin-1 in renal disease. (2001) (266)
- Reappraisal of the pathogenesis and consequences of hyperuricemia in hypertension, cardiovascular disease, and renal disease. (1999) (264)
- Infusion of platelet-derived growth factor or basic fibroblast growth factor induces selective glomerular mesangial cell proliferation and matrix accumulation in rats. (1993) (260)
- Osteopontin expression in angiotensin II-induced tubulointerstitial nephritis. (1994) (245)
- New mechanism for glomerular injury. Myeloperoxidase-hydrogen peroxide-halide system. (1987) (241)
- The glomerular response to injury: progression or resolution? (1994) (240)
- Mycophenolate mofetil prevents salt-sensitive hypertension resulting from angiotensin II exposure. (2001) (236)
- Hepatitis B infection and renal disease: clinical, immunopathogenetic and therapeutic considerations. (1990) (229)
- Complement membrane attack complex stimulates production of reactive oxygen metabolites by cultured rat mesangial cells. (1986) (229)
- Tubulointerstitial disease in aging: evidence for underlying peritubular capillary damage, a potential role for renal ischemia. (1998) (219)
- Vascular endothelial growth factor accelerates renal recovery in experimental thrombotic microangiopathy. (2000) (208)
- The activated mesangial cell: a glomerular "myofibroblast"? (1992) (206)
- Glomerular cells, extracellular matrix accumulation, and the development of glomerulosclerosis in the remnant kidney model. (1992) (203)
- Platelets mediate glomerular cell proliferation in immune complex nephritis induced by anti-mesangial cell antibodies in the rat. (1990) (202)
- Risk of death among chronic dialysis patients infected with hepatitis C virus. (1998) (199)
- Role of immunocompetent cells in nonimmune renal diseases. (2001) (197)
- Cellular proliferation and macrophage influx precede interstitial fibrosis in cyclosporine nephrotoxicity. (1995) (188)
- Participation of glomerular endothelial cells in the capillary repair of glomerulonephritis. (1995) (184)
- Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis. (1998) (183)
- Human renal cortical interstitial cells with some features of smooth muscle cells participate in tubulointerstitial and crescentic glomerular injury. (1994) (180)
- Tubulointerstitial disease in glomerulonephritis. Potential role of osteopontin (uropontin). (1994) (177)
- Renal manifestations of hepatitis C virus infection. (1994) (176)
- Sex differences in uric acid and risk factors for coronary artery disease. (2001) (175)
- Heparin suppresses mesangial cell proliferation and matrix expansion in experimental mesangioproliferative glomerulonephritis. (1993) (171)
- Mycophenolate mofetil prevents salt-sensitive hypertension resulting from nitric oxide synthesis inhibition. (2001) (167)
- Salt-sensitive hypertension develops after short-term exposure to Angiotensin II. (1999) (164)
- Unearthing uric acid: an ancient factor with recently found significance in renal and cardiovascular disease. (2006) (163)
- Restricted diet rescues rat enteric motor neurones from age related cell death (2000) (147)
- Rat glomerular mesangial cells synthesize basic fibroblast growth factor. Release, upregulated synthesis, and mitogenicity in mesangial proliferative glomerulonephritis. (1992) (142)
- The human neutrophil serine proteinases, elastase and cathepsin G, can mediate glomerular injury in vivo (1988) (140)
- Hypothesis: the role of acquired tubulointerstitial disease in the pathogenesis of salt-dependent hypertension. (1997) (137)
- Developmental patterns of PDGF B-chain, PDGF-receptor, and alpha-actin expression in human glomerulogenesis. (1992) (136)
- Hepatitis C virus infection and membranoproliferative glomerulonephritis in Japan. (1995) (133)
- Structural characterization of the mesangial cell type IV collagenase and enhanced expression in a model of immune complex-mediated glomerulonephritis. (1992) (132)
- Depletion of C6 prevents development of proteinuria in experimental membranous nephropathy in rats. (1989) (131)
- Age-related glomerulosclerosis and interstitial fibrosis in Milan normotensive rats: a podocyte disease. (1997) (130)
- Hyperuricemia exacerbates chronic cyclosporine nephropathy. (2001) (125)
- Mechanisms of progressive renal disease in glomerulonephritis. (1994) (124)
- Cyclin kinase inhibitors are increased during experimental membranous nephropathy: potential role in limiting glomerular epithelial cell proliferation in vivo. (1997) (124)
- Role of platelet-derived growth factor in glomerular disease. (1993) (123)
- Role of the complement membrane attack complex (C5b-9) in mediating experimental mesangioproliferative glomerulonephritis. (1996) (120)
- Demonstration of PDGF B-chain mRNA in glomeruli in mesangial proliferative nephritis by in situ hybridization. (1991) (120)
- Extraglomerular origin of the mesangial cell after injury. A new role of the juxtaglomerular apparatus. (1997) (119)
- Role of intrinsic renal cells versus infiltrating cells in glomerular crescent formation. (1998) (118)
- Hepatitis C virus associated membranous glomerulonephritis. (1995) (117)
- Osteopontin expression in fetal and mature human kidney. (1999) (117)
- PDGF-receptor localizes to mesangial, parietal epithelial, and interstitial cells in human and primate kidneys. (1993) (115)
- Visceral glomerular epithelial cells can proliferate in vivo and synthesize platelet-derived growth factor B-chain. (1993) (110)
- Markers of complement-dependent and complement-independent glomerular visceral epithelial cell injury in vivo. Expression of antiadhesive proteins and cytoskeletal changes. (1992) (109)
- Changes in cell-cycle protein expression during experimental mesangial proliferative glomerulonephritis. (1996) (107)
- Role of oxidants and proteases in glomerular injury. (1994) (106)
- Cyclosporine A induced arteriolopathy in a rat model of chronic cyclosporine nephropathy. (1995) (105)
- The effects of soluble recombinant complement receptor 1 on complement-mediated experimental glomerulonephritis. (1995) (104)
- Platelets mediate neutrophil-dependent immune complex nephritis in the rat. (1988) (103)
- Post-cyclosporine-mediated hypertension and nephropathy: amelioration by vascular endothelial growth factor. (2001) (102)
- Renal injury and salt-sensitive hypertension after exposure to catecholamines. (1999) (101)
- Differential expression of transforming growth factor-beta isoforms and receptors in experimental membranous nephropathy. (1996) (99)
- Hypokalemia induces renal injury and alterations in vasoactive mediators that favor salt sensitivity. (2001) (97)
- Neutrophil fate in experimental glomerular capillary injury in the rat. Emigration exceeds in situ clearance by apoptosis. (1997) (95)
- Thrombospondin 1 precedes and predicts the development of tubulointerstitial fibrosis in glomerular disease in the rat. (1998) (95)
- Mesangial cell proliferation mediated by PDGF and bFGF is determined by levels of the cyclin kinase inhibitor p27Kip1. (1997) (95)
- C5b-9 membrane attack complex mediates endothelial cell apoptosis in experimental glomerulonephritis. (2000) (94)
- Mechanisms of increased venous smooth muscle tone in desoxycorticosterone acetate-salt hypertension. (2000) (94)
- Chronic potassium depletion induces renal injury, salt sensitivity, and hypertension in young rats. (2001) (94)
- Osteopontin expression in progressive renal injury in remnant kidney: role of angiotensin II. (2000) (93)
- Renal cortical vasoconstriction contributes to development of salt-sensitive hypertension after angiotensin II exposure. (2001) (93)
- A functional role for osteopontin in experimental crescentic glomerulonephritis in the rat. (1998) (92)
- Hepatitis C virus-associated glomerulonephritis. Effect of alpha-interferon therapy. (1994) (91)
- Platelet-complement interactions in mesangial proliferative nephritis in the rat. (1991) (90)
- IL-1 up-regulates osteopontin expression in experimental crescentic glomerulonephritis in the rat. (1999) (90)
- SPARC is expressed in renal interstitial fibrosis and in renal vascular injury. (1996) (90)
- Increased urinary excretion of C5b-9 distinguishes passive Heymann nephritis in the rat. (1989) (87)
- Elevated urinary excretion of the C5b-9 complex in membranous nephropathy. (1991) (87)
- Experimental mesangial proliferative glomerulonephritis (the anti-Thy-1.1 model). (1999) (86)
- Thrombospondin 1 is expressed by proliferating mesangial cells and is up-regulated by PDGF and bFGF in vivo. (1995) (84)
- Multiple roles for platelet-derived growth factor in renal disease. (1995) (84)
- Renal proliferative and phenotypic changes in rats with two-kidney, one-clip Goldblatt hypertension. (1994) (81)
- Hepatitis C virus-associated glomerulonephritis. (1995) (80)
- Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV. (1996) (79)
- Morphologic correlates of glomerular oxidant injury induced by the myeloperoxidase-hydrogen peroxide-halide system of the neutrophil. (1988) (79)
- De novo glomerular osteopontin expression in rat crescentic glomerulonephritis. (1998) (78)
- Participation of the myeloperoxidase-H2O2-halide system in immune complex nephritis. (1987) (77)
- CD59 protects glomerular endothelial cells from immune-mediated thrombotic microangiopathy in rats. (1998) (75)
- SPARC is expressed by mesangial cells in experimental mesangial proliferative nephritis and inhibits platelet-derived-growth-factor-medicated mesangial cell proliferation in vitro. (1996) (74)
- Vascular endothelial growth factor (VEGF121) protects rats from renal infarction in thrombotic microangiopathy. (2001) (72)
- A new model of renal microvascular endothelial injury. (1997) (71)
- The cytoskeletal linking proteins, moesin and radixin, are upregulated by platelet-derived growth factor, but not basic fibroblast growth factor in experimental mesangial proliferative glomerulonephritis. (1996) (71)
- Mesangial cells in the pathogenesis of progressive glomerular disease in animal models (1992) (70)
- The cyclin kinase inhibitor p21CIP1/WAF1 limits glomerular epithelial cell proliferation in experimental glomerulonephritis. (1999) (70)
- Membrane attack complex deposition in experimental glomerular injury. (1985) (69)
- The effect of drugs on fetal heart rate variability. (1978) (66)
- Thiazide-induced subtle renal injury not observed in states of equivalent hypokalemia. (2007) (65)
- Osteopontin regulation in cultured rat renal epithelial cells. (1997) (65)
- The plasma membrane-actin linking protein, ezrin, is a glomerular epithelial cell marker in glomerulogenesis, in the adult kidney and in glomerular injury. (1998) (64)
- Osteopontin expression in human crescentic glomerulonephritis. (2000) (63)
- Glomerular epithelial cells secrete a glomerular basement membrane-degrading metalloproteinase. (1992) (62)
- Glomerular C3c localization indicates ongoing immune deposit formation and complement activation in experimental glomerulonephritis. (1993) (62)
- Platelet-derived growth factor: a potentially important cytokine in glomerular disease. (1992) (60)
- Modulation of experimental mesangial proliferative nephritis by interferon-gamma. (1995) (53)
- Glomerular cells in vitro versus the glomerulus in vivo. (1994) (51)
- Altered glomerular extracellular matrix synthesis in experimental membranous nephropathy. (1992) (51)
- Glomerulonephritis in renal allografts associated with hepatitis C infection: a possible relationship with transplant glomerulopathy in two cases. (1995) (50)
- Platelet-derived growth factor A-chain expression in developing and mature human kidneys and in Wilms' tumor. (1995) (49)
- Paroxysmal nocturnal haemoglobinuria: Nature's gene therapy? (2002) (48)
- Hepatitis C virus and rheumatic disease. (1996) (48)
- A role for P-selectin in neutrophil and platelet infiltration in immune complex glomerulonephritis. (1997) (47)
- The pathogenesis of tubulointerstitial disease associated with glomerulonephritis: the glomerular cytokine theory. (1995) (46)
- Mechanisms and kinetics for platelet and neutrophil localization in immune complex nephritis. (1989) (46)
- Endogenous fibroblast growth factor-2 mediates cytotoxicity in experimental mesangioproliferative glomerulonephritis. (1998) (46)
- Assessment of IgH PCR strategies in multiple myeloma. (1996) (46)
- Protective role of nitric oxide in a model of thrombotic microangiopathy in rats. (2001) (46)
- Nerve growth factor receptor expression in fetal, mature, and diseased human kidneys. (1993) (45)
- Cytokines, growth factors and renal injury: where do we go now? (1997) (45)
- Osteopontin in chronic puromycin aminonucleoside nephrosis. (1997) (45)
- Dissociation of mesangial cell migration and proliferation in experimental glomerulonephritis. (1999) (43)
- Renal microvascular injury induced by antibody to glomerular endothelial cells is mediated by C5b-9. (1997) (43)
- Much ado about nothing, or much to do about something? The continuing controversy over the role of uric acid in cardiovascular disease. (2000) (42)
- Role of endothelin in hypertension of experimental chronic renal failure. (1997) (42)
- Overexpression of Crry protects mesangial cells from complement-mediated injury. (1997) (41)
- Urinary excretion of C5b-9 reflects disease activity in passive Heymann nephritis. (1989) (40)
- C5b-9 increases albumin permeability of isolated glomeruli in vitro. (1994) (38)
- Uric acid and hypertension: an age-related relationship? (2009) (37)
- The platelet glycoprotein Ia/IIa gene polymorphism C807T/G873A: a novel risk factor for retinal vein occlusion (2003) (37)
- Resistance of neoplasms to immunological destruction: role of a macrophage chemotaxis inhibitor (1978) (36)
- Urinary excretion of the C5b-9 membrane attack complex of complement is a marker of immune disease activity in autologous immune complex nephritis. (1991) (36)
- Cyclosporin A inhibits prostaglandin E2 formation by rat mesangial cells in culture. (1989) (35)
- Peripheral blood stem cell transplantation in myeloma using CD34 selected cells. (1996) (34)
- Osteopontin expression in human cyclosporine toxicity. (2001) (34)
- Distinct patterns of glomerular disease in Lima, Peru. (2000) (33)
- Immunopathology of periodontal disease. I. Immunologic profiles in periodontitis and juvenile periodontitis. (1980) (32)
- Hepatitis C--associated glomerular disease in liver transplant recipients. (1995) (32)
- Monoclonal immunoglobulin deposition disease in a renal allograft: probable recurrent disease in a patient without myeloma. (1989) (32)
- Transfected CD59 protects mesangial cells from injury induced by antibody and complement. (1996) (32)
- Treatment of hepatitis C-associated glomerular disease. (2000) (30)
- Mechanisms of clearance of immune complexes from peritubular capillaries in the rat. (1991) (30)
- Beneficial effects of systemic immunoglobulin in experimental membranous nephropathy. (1996) (30)
- Antibody-mediated suppression of grafted lymphoma. IV. Influence of time of tumor residency in vivo and tumor size upon the effectiveness of suppression by syngeneic antibody (1976) (29)
- Thrombospondin peptides are potent inhibitors of mesangial and glomerular endothelial cell proliferation in vitro and in vivo. (1999) (29)
- Characteristics of a monoclonal antibody (RM124) against acute myelocytic leukemia cells. (1984) (28)
- Suppression of antibody-sensitized tumor cells by macrophages: insufficient supply or activation of macrophages within large tumors. (1979) (28)
- Osteopontin expression, tubulointerstitial disease, and essential hypertension. (1998) (28)
- Analysis of CD34+ cell subsets in stem cell harvests can more reliably predict rapidity and durability of engraftment than total CD34+ cell dose, but steady state levels do not correlate with bone marrow reserve (2001) (25)
- Antibody-mediated suppression of tumor growth. II. Macrophage and platelet cooperation with murine IgG1 isolated from alloantiserum. (1977) (25)
- Biocompatibility of hemodialysis membranes: evaluation in an ovine model. (1993) (22)
- A vasodepressor substance of the human placenta. (1969) (21)
- Circulating primitive stem cells in paroxysmal nocturnal hemoglobinuria (PNH) are predominantly normal in phenotype but granulocyte colony-stimulating factor treatment mobilizes mainly PNH stem cells. (1998) (20)
- Antibody-mediated suppression of tumor growth. I. Suppression by murine IgG1 isolated from alloantiserum. (1977) (20)
- Role of cytokines and growth factors in glomerulonephritis: a chance for future therapeutic intervention. (1996) (20)
- Mechanisms of endothelin-induced venoconstriction in isolated guinea pig mesentery. (1999) (19)
- Requirements for the successful application of autologous bone marrow transplantation in the treatment of selected malignancies. (1980) (19)
- Tumor cell cytostasis by macrophages and antibody in vitro. I. Resolution into contact-dependent and contact-independent steps. (1978) (18)
- Autologous bone marrow transplantation in the treatment of selected human malignancies: The Johns Hopkins Oncology Center Program. (1979) (18)
- Complement activation by biomaterials. (1990) (17)
- C6 depletion reduces proteinuria in experimental nephropathy induced by a nonglomerular antigen. (1991) (17)
- Granulomatous synovitis and osteitis caused by Sporothrix schenckii. (1975) (17)
- Complement activation during extracorporeal therapy: biochemistry, cell biology and clinical relevance. (1994) (16)
- A modification of cellulose that facilitates the control of complement activation. (1990) (15)
- Immunotherapy of cancer with antibody. (1976) (15)
- Mechanisms of tumor immunity: the role of antibody and nonimmune effectors. (1978) (15)
- Detection of clonal immunoglobulin gene rearrangements in the PBPC harvests of patients with acute lymphoblastic leukaemia. (1995) (14)
- Monoclonal antibody against a differentiation antigen on human leukemia cells: cross-reactivity with rat leukemia and suppression of rat leukemia in vivo. (1983) (12)
- Immunologically Mediated Tubulointerstitial Nephritis (1984) (12)
- Mechanisms of cyclosporine-induced interstitial fibrosis. (1994) (12)
- Infusion of ovine C5a into sheep mimics the inflammatory response of hemodialysis. (1996) (12)
- Antibody-mediated suppression of tumor growth. III. Molecular assay of murine IgG1 alloantibody required to cause tumor suppression in vivo. (1977) (11)
- A simplified radioimmunoassay for antibodies causing immune cytopenia. (1985) (11)
- The mystery of the antineutrophil cytoplasmic antibodies. (1995) (11)
- Systemic monoclonal antibody therapy for eliminating minimal residual leukemia in a rat bone marrow transplant model. (1989) (10)
- Unilateral Testicular Hypoplasia in a Goat (1983) (10)
- A cytotoxic monoclonal anti-leukemia antibody binds to histone H1. (1990) (10)
- Aprotinin, an antifibrinolytic drug, attenuates bradykinin-induced permeability in conscious rats via platelets and neutrophils. (1997) (9)
- Immunoblotting characterization of neutrophil antigenic targets in autoimmune neutropenia. (1989) (9)
- Intravenous immunoglobulin protects against experimental thrombotic microangiopathy. (2001) (8)
- The diagnostic usefulness of measuring antineutrophil antibodies in neutropenic patients. (1986) (8)
- TGF-beta in glomerular disease. (1998) (8)
- Role of endogenous complement in monoclonal IgM antibody-dependent leukemia suppression in vivo: participation of C3b. (1985) (8)
- Detection of clonal immunoglobulin gene rearrangements in the peripheral blood progenitor cells of patients with multiple myeloma: the potential role of purging with CD34 positive selection (1996) (7)
- Have we ignored the role of oncotic pressure in the pathogenesis of glomerulosclerosis? (1997) (7)
- In vivo gene transfer, Koch's postulates, and renal disease. (1993) (7)
- Tumor cell cytostasis by macrophages and antibody in vitro. II. Isolation and characterization of suppressed cells. (1978) (7)
- Hepatitis C virus-associated glomerulonephritis. (1995) (6)
- An evaluation of four automated coagulation instruments. (1978) (6)
- Cytokine networks and the pathogenesis of glomerulonephritis. (1993) (6)
- Mobilisation and reinfusion of Philadelphia negative peripheral blood mononuclear cells in chronic myeloid leukaemia with hydroxyurea and G-CSF. (1997) (5)
- The detection and clinical significance of monoclonality in lymphoproliferative disorders (1995) (4)
- Lack of correlation of growth attenuation of murine lymphoma caused by in vitro passage with loss of lactate dehydrogenase virus. (1983) (4)
- Glomerulosclerosis in the rat induced by repeated immune-mediated mesangial cell injury. (1993) (4)
- A subline of the Brown Norway myeloid leukemia in the Lewis x Brown Norway rat: in vivo growth characteristics and development of an in vitro clonogenic assay. (1989) (3)
- Is there a hepatitis C virus-associated membranoproliferative glomerulonephritis? (1997) (2)
- Antibody-mediated Tumour Supression: Some Recent Developments and Possible Role in Natural Resistance to Tumours (1983) (2)
- Anti-GOR in chronic HCV patients with membranoproliferative glomerulonephritis. (1996) (2)
- Macrophage shortage within tumor diminishes effectiveness of igg1 antibody-mediated suppression. Abstr. (1977) (2)
- The design of cellulosic based membranes that do not activate complement. (1989) (1)
- Suppression of tumor growth by igg1 antibody. Cooperation with macrophages and platelets. Abstr. (1976) (1)
- 4P-1173 Uric acid induced the expression of C-reactive protein (CRP) in vascular smooth muscle cells (VSMC) via MAP kinase-dependent and angiotensin II-mediated pathway (2003) (1)
- A free-ranging roundtable discussion on hypertension (2005) (1)
- Rejection of tumor grafts after passage of the tumor cells in vitro: failure to correlate attenuated growth in vivo with presence or loss of viral products that suppress macrophage functions. Abstr. (1982) (0)
- Role of Fas (CD95) in tubulointerstitial disease induced by unilateral ureteric obstruction. (1999) (0)
- Influx of 45Ca++ into U937 cells after attack by sublytic doses of complement (1984) (0)
- Effects of tranexamic acid and aprotinin on PAF-induced vascular permeability in normal, thrombocytopenic or neutropenic rats (1997) (0)
- ROLE OF ANGIOTENSIN II (AII) AND NITRIC OXIDE (NO) IN THE APOPTOSIS ACCOMPANYING CYCLOSPORINE (CSA) MEDIATED INTERSTITIAL FIBROSISS. •1695 (1997) (0)
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