Rob Klose
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Canadian geneticist
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Rob Klosebiology Degrees
Biology
#4501
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#6702
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Genetics
#1173
World Rank
#1273
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Molecular Biology
#1601
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#1629
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Biology
Why Is Rob Klose Influential?
(Suggest an Edit or Addition)According to Wikipedia, Rob Klose is a Canadian researcher and Professor of Genetics at the Department of Biochemistry, University of Oxford. His research investigates how chromatin-based and epigenetic mechanisms contribute to the ways in which gene expression is regulated.
Rob Klose's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Genomic DNA methylation: the mark and its mediators. (2006) (2451)
- JmjC-domain-containing proteins and histone demethylation (2006) (1156)
- Regulation of histone methylation by demethylimination and demethylation (2007) (857)
- The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases (2011) (851)
- The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36 (2006) (647)
- Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation (2014) (602)
- PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. (2007) (484)
- Understanding the relationship between DNA methylation and histone lysine methylation (2014) (438)
- The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase (2007) (432)
- KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands (2012) (411)
- DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG. (2005) (364)
- Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators (2010) (315)
- CpG Islands Recruit a Histone H3 Lysine 36 Demethylase (2010) (307)
- Targeting Polycomb systems to regulate gene expression: modifications to a complex story (2015) (306)
- Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment (2014) (295)
- MeCP2 binding to DNA depends upon hydration at methyl-CpG. (2008) (271)
- Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function (2009) (229)
- Dynamic protein methylation in chromatin biology (2008) (203)
- ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection (2013) (202)
- Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors (2010) (198)
- Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates (2013) (185)
- The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells (2017) (154)
- Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression (2019) (154)
- PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase. (2010) (154)
- PRC1 Catalytic Activity Is Central to Polycomb System Function (2019) (148)
- Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase (2007) (140)
- Histone demethylases in chromatin biology and beyond (2015) (133)
- 5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation. (2013) (131)
- Chromatin Sampling—An Emerging Perspective on Targeting Polycomb Repressor Proteins (2013) (120)
- The trithorax-group protein Lid is a histone H3 trimethyl-Lys4 demethylase (2007) (113)
- Interferon‐γ‐induced chromatin remodeling at the CIITA locus is BRG1 dependent (2002) (112)
- Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. (2012) (109)
- CpG island chromatin (2011) (102)
- Demethylation of Histone H3K36 and H3K9 by Rph1: a Vestige of an H3K9 Methylation System in Saccharomyces cerevisiae? (2007) (102)
- PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes (2017) (100)
- Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells (2020) (99)
- The molecular principles of gene regulation by Polycomb repressive complexes (2021) (94)
- MeCP2 Behaves as an Elongated Monomer That Does Not Stably Associate with the Sin3a Chromatin Remodeling Complex* (2004) (93)
- RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes (2016) (92)
- Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved (2016) (75)
- The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin (2017) (72)
- MeCP2 Repression Goes Nonglobal (2003) (65)
- MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia (2017) (63)
- Interferon-gamma-induced chromatin remodeling at the CIITA locus is BRG1 dependent. (2002) (57)
- Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes (2018) (49)
- Understanding the interplay between CpG island-associated gene promoters and H3K4 methylation☆ (2020) (48)
- Recognition of CpG Island Chromatin by KDM2A Requires Direct and Specific Interaction with Linker DNA (2011) (47)
- PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency (2020) (44)
- Analysis of Genome Architecture during SCNT Reveals a Role of Cohesin in Impeding Minor ZGA. (2020) (34)
- Molecular biology. MeCP2 repression goes nonglobal. (2003) (32)
- Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors (2019) (31)
- Bio-CAP: a versatile and highly sensitive technique to purify and characterise regions of non-methylated DNA (2011) (29)
- BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome (2020) (27)
- Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy (2020) (27)
- Histone H2A monoubiquitylation and p38-MAPKs regulate immediate-early gene-like reactivation of latent retrovirus HTLV-1. (2018) (26)
- Histone lysine methylation: an epigenetic modification? (2010) (20)
- Demethylation of Histone H 3 K 36 and H 3 K 9 by Rph 1 : a Vestige of an H 3 K 9 Methylation System in Saccharomyces cerevisiae ? (2007) (19)
- FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment (2018) (19)
- Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction (2020) (18)
- KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity (2019) (17)
- Characterization of an overexpressed spindle protein during a baculovirus infection. (2000) (17)
- Correction: PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes (2017) (15)
- Yeast Jhd 2 p is a histone H 3 Lys 4 trimethyl demethylase (2007) (15)
- Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes (2021) (13)
- Cohesin disrupts polycomb-dependent chromosome interactions (2019) (12)
- CDK-Mediator and FBXL19 prime developmental genes for activation by promoting atypical regulatory interactions (2020) (8)
- Histone H3 Arg2 methylation provides alternative directions for COMPASS (2007) (7)
- Distinct roles for CKM–Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction (2021) (5)
- Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis (2016) (5)
- Recycling of modified H2A-H2B provides short-term memory of chromatin states (2023) (4)
- Interferon-g-induced chromatin remodeling at the CIITA locus is BRG 1 dependent (4)
- Getting under the skin of Polycomb-dependent gene regulation (2021) (3)
- ATACing DNA Methylation during Differentiation. (2020) (3)
- A CpG island-encoded mechanism protects genes from premature transcription termination (2022) (1)
- Author response: RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes (2016) (1)
- Erratum: Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase (2007) (1)
- FBXL19 recruits CDK-Mediator to the CpG islands of developmental genes to prime them for activation during lineage commitment (2018) (0)
- Author response: The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells (2016) (0)
- 8-Hydroxyquinoline-5-Carboxylic Acid is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation (2013) (0)
- Polycomb repression during S/G2 phases restrain initiation of cell differentiation to the G1 phase of the cell cycle (2022) (0)
- PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment (2022) (0)
- Understanding the role of CFP1 at CpG islands (2014) (0)
- Biochemical analysis of MeCP2 (2005) (0)
- Biochemical Identification of Nonmethylated DNA by BioCAP-Seq. (2018) (0)
- Biochemical characterisation of KDM2A (2012) (0)
- Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells (2023) (0)
- The Crystal Structure of Methyl-CpG Binding Domain of Human MeCP2 in Complex with a Methylated DNA Sequence from BDNF (2008) (0)
- Erratum: Histone merry-go-round (2007) (0)
- KDM2B links recognition of CpG islands to polycomb domain formation in vivo (2013) (0)
- Author response: KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands (2012) (0)
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