Robert B. Darnell
#32,915
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American biochemist
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Robert B. Darnellbiology Degrees
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#1657
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#2713
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#803
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Molecular Biology
#598
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#613
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#159
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Genetics
#567
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#646
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#212
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Biochemistry
#607
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#699
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#201
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Biology
Robert B. Darnell's Degrees
- Doctorate Medicine Columbia University
Why Is Robert B. Darnell Influential?
(Suggest an Edit or Addition)According to Wikipedia, Robert Bernard Darnell is an American neurooncologist and neuroscientist, founding director and former CEO of the New York Genome Center, the Robert and Harriet Heilbrunn Professor of Cancer Biology at The Rockefeller University, and an Investigator of the Howard Hughes Medical Institute. His research into rare autoimmune brain diseases led to the invention of the HITS-CLIP method to study RNA regulation, and he is developing ways to explore the regulatory portions—known as the "dark matter"—of the human genome.
Robert B. Darnell's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism (2011) (1771)
- FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism (2011) (1771)
- De Novo Gene Disruptions in Children on the Autistic Spectrum (2012) (1335)
- De Novo Gene Disruptions in Children on the Autistic Spectrum (2012) (1335)
- HITS-CLIP yields genome-wide insights into brain alternative RNA processing (2008) (1301)
- HITS-CLIP yields genome-wide insights into brain alternative RNA processing (2008) (1301)
- Microarray Identification of FMRP-Associated Brain mRNAs and Altered mRNA Translational Profiles in Fragile X Syndrome (2001) (1102)
- Microarray Identification of FMRP-Associated Brain mRNAs and Altered mRNA Translational Profiles in Fragile X Syndrome (2001) (1102)
- CLIP Identifies Nova-Regulated RNA Networks in the Brain (2003) (1083)
- Ago HITS-CLIP decodes miRNA-mRNA interaction maps (2009) (1057)
- A call for transparent reporting to optimize the predictive value of preclinical research (2012) (1036)
- Paraneoplastic syndromes involving the nervous system. (2003) (928)
- Fragile X Mental Retardation Protein Targets G Quartet mRNAs Important for Neuronal Function (2001) (923)
- Fragile X Mental Retardation Protein Targets G Quartet mRNAs Important for Neuronal Function (2001) (923)
- Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. (1997) (797)
- RNA processing and its regulation: global insights into biological networks (2010) (662)
- CLIP: a method for identifying protein-RNA interaction sites in living cells. (2005) (613)
- A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation (2015) (554)
- An RNA map predicting Nova-dependent splicing regulation (2006) (552)
- Vaccine Breakthrough Infections with SARS-CoV-2 Variants (2021) (520)
- Nova regulates brain-specific splicing to shape the synapse (2005) (518)
- Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells (2001) (470)
- Assembly and diploid architecture of an individual human genome via single-molecule technologies (2015) (433)
- Tumor-specific killer cells in paraneoplastic cerebellar degeneration (1998) (430)
- Tumor-specific killer cells in paraneoplastic cerebellar degeneration (1998) (430)
- Nova-1 Regulates Neuron-Specific Alternative Splicing and Is Essential for Neuronal Viability (2000) (428)
- The translation of translational control by FMRP: therapeutic targets for FXS (2013) (409)
- Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data (2011) (398)
- m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover (2017) (380)
- A Hierarchy of Hu RNA Binding Proteins in Developing and Adult Neurons (1997) (370)
- HITS‐CLIP: panoramic views of protein–RNA regulation in living cells (2010) (366)
- An alternative mode of microRNA target recognition (2012) (355)
- Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting. (2012) (330)
- HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism. (2014) (329)
- Sequence-Specific RNA Binding by a Nova KH Domain Implications for Paraneoplastic Disease and the Fragile X Syndrome (2000) (326)
- Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system (1993) (320)
- Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes. (2005) (311)
- Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes. (2005) (311)
- Hepatitis C Virus RNA Functionally Sequesters miR-122 (2015) (297)
- Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. (2000) (290)
- Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy (2012) (288)
- EBV and human microRNAs co‐target oncogenic and apoptotic viral and human genes during latency (2012) (285)
- Integrative Modeling Defines the Nova Splicing-Regulatory Network and Its Combinatorial Controls (2010) (280)
- Onconeural antigens and the paraneoplastic neurologic disorders: at the intersection of cancer, immunity, and the brain. (1996) (277)
- Fragile X Mental Retardation Protein Is Associated with Translating Polyribosomes in Neuronal Cells (2004) (272)
- Fragile X Mental Retardation Protein Is Associated with Translating Polyribosomes in Neuronal Cells (2004) (272)
- The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo (1997) (270)
- Two ZBP1 KH domains facilitate β-actin mRNA localization, granule formation, and cytoskeletal attachment (2003) (250)
- Genomic Patterns of De Novo Mutation in Simplex Autism (2017) (247)
- Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems. (1999) (246)
- A novel adaptor-related protein complex (1996) (245)
- Splicing Regulation in Neurologic Disease (2006) (243)
- Detection and treatment of activated T cells in the cerebrospinal fluid of patients with paraneoplastic cerebellar degeneration (2000) (240)
- Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis (2014) (240)
- miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity (2015) (240)
- Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis (2014) (240)
- A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing. (2000) (238)
- Genome Sequencing of Autism-Affected Families Reveals Disruption of Putative Noncoding Regulatory DNA. (2016) (234)
- The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia. (1998) (221)
- Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation (2018) (219)
- Paraneoplastic syndromes affecting the nervous system. (2006) (215)
- Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction (2011) (199)
- Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction (2011) (199)
- BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice (2015) (184)
- Neuronal Elav-like (Hu) Proteins Regulate RNA Splicing and Abundance to Control Glutamate Levels and Neuronal Excitability (2012) (180)
- Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk (2019) (178)
- RNA binding proteins and the regulation of neuronal synaptic plasticity (2006) (174)
- Paraneoplastic neurological degenerations: keys to tumour immunity (2004) (171)
- Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. (2012) (171)
- ATM binds to β-adaptin in cytoplasmic vesicles (1998) (163)
- Common Molecular Pathways Mediate Long-Term Potentiation of Synaptic Excitation and Slow Synaptic Inhibition (2005) (159)
- Apoptotic Cells Deliver Processed Antigen to Dendritic Cells for Cross-Presentation (2005) (159)
- Nova2 Regulates Neuronal Migration through an RNA Switch in Disabled-1 Signaling (2010) (156)
- The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain. (2000) (156)
- The splice of life: Alternative splicing and neurological disease (2001) (154)
- A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ (2019) (153)
- CLIP: crosslinking and immunoprecipitation of in vivo RNA targets of RNA-binding proteins. (2008) (152)
- RNA protein interaction in neurons. (2013) (150)
- β-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein (1995) (147)
- Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP (2015) (145)
- Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP (2015) (145)
- A Mouse Model of the Human Fragile X Syndrome I304N Mutation (2009) (132)
- A Mouse Model of the Human Fragile X Syndrome I304N Mutation (2009) (132)
- FMRP RNA targets: identification and validation (2005) (131)
- Nova Regulates GABAA Receptor γ2 Alternative Splicing via a Distal Downstream UCAU-Rich Intronic Splicing Enhancer (2003) (130)
- Nova autoregulation reveals dual functions in neuronal splicing (2005) (128)
- The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development (2002) (121)
- Endodormancy, paradormancy, and ecodormancy—physiological terminology and classification for dormancy research (1987) (120)
- Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data (2018) (117)
- Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain (2016) (116)
- The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival. (1999) (115)
- Cytoplasmic RNA-binding proteins and the control of complex brain function. (2012) (114)
- Paraneoplastic neurologic disease antigens: RNA-binding proteins and signaling proteins in neuronal degeneration. (2001) (113)
- Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains. (1999) (113)
- Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs (2009) (110)
- Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs (2009) (110)
- A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration. (2016) (106)
- Alternative Splicing Microarrays Reveal Functional Expression of Neuron-specific Regulators in Hodgkin Lymphoma Cells* (2005) (104)
- Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer (2014) (103)
- Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing (2009) (100)
- Fibroblast Growth Factor Signaling Controls Liver Size in Mice With Humanized Livers. (2015) (100)
- Neuroimmunology of the paraneoplastic neurological degenerations. (2004) (95)
- Patients with lung cancer and paraneoplastic Hu syndrome harbor HuD-specific type 2 CD8+ T cells. (2009) (93)
- A Post-Transcriptional Regulatory Mechanism Restricts Expression of the Paraneoplastic Cerebellar Degeneration Antigen cdr2 to Immune Privileged Tissues (1997) (93)
- A Post-Transcriptional Regulatory Mechanism Restricts Expression of the Paraneoplastic Cerebellar Degeneration Antigen cdr2 to Immune Privileged Tissues (1997) (93)
- Cdr2, a target antigen of naturally occuring human tumor immunity, is widely expressed in gynecological tumors. (2000) (92)
- Cdr2, a target antigen of naturally occuring human tumor immunity, is widely expressed in gynecological tumors. (2000) (92)
- Evolution of Nova-Dependent Splicing Regulation in the Brain (2007) (91)
- Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs (2020) (90)
- Whole‐Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma (2018) (90)
- Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition (2017) (87)
- NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure (2013) (87)
- Mapping and characterization of structural variation in 17,795 human genomes (2020) (84)
- NOVA2-mediated RNA regulation is required for axonal pathfinding during development (2016) (84)
- RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares. (2020) (79)
- Structural insights into mis-regulation of protein kinase A in human tumors (2015) (77)
- ATM binds to beta-adaptin in cytoplasmic vesicles. (1998) (71)
- The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite (2009) (70)
- IL-2 Is Required for the Activation of Memory CD8+ T Cells via Antigen Cross-Presentation1 (2006) (70)
- ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity (2018) (69)
- Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue (2018) (69)
- Germline NPM1 mutations lead to altered rRNA 2’-O-methylation and cause dyskeratosis congenita (2019) (68)
- Observing the invisible: successful tumor immunity in humans (2003) (67)
- Prediction of clustered RNA-binding protein motif sites in the mammalian genome (2013) (64)
- Pre-mRNA processing includes N6 methylation of adenosine residues that are retained in mRNA exons and the fallacy of “RNA epigenetics” (2018) (64)
- PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage. (2016) (64)
- Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes (2015) (63)
- Paraneoplastic neurologic disorders: windows into neuronal function and tumor immunity. (2004) (62)
- Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer. (2017) (61)
- Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1. (2011) (59)
- Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1. (2011) (59)
- Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice. (2013) (59)
- Differential expression of the human gonadotropin alpha gene in ectopic and eutopic cells (1985) (56)
- Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-α/β on antigen cross-presentation (2007) (56)
- cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation (2017) (54)
- Disease variants in genomes of 44 centenarians (2014) (54)
- NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord (2016) (53)
- CLIP (cross-linking and immunoprecipitation) identification of RNAs bound by a specific protein. (2012) (52)
- The fragile X mental retardation protein, FMRP, recognizes G-quartets. (2004) (51)
- The fragile X mental retardation protein, FMRP, recognizes G-quartets. (2004) (51)
- FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory (2019) (48)
- FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory (2019) (48)
- Cholesterol levels in Fragile X syndrome (2015) (47)
- Expression and structures of human placental hormone genes as a function of placental development. (1982) (46)
- The Future of Cross-Linking and Immunoprecipitation (CLIP). (2018) (45)
- The distribution of glycosyl-phosphatidylinositol anchored proteins is differentially regulated by serum and insulin. (1989) (45)
- The neuronal splicing factor Nova controls alternative splicing in N-type and P-type CaV2 calcium channels (2010) (44)
- The neuronal nuclear antigen recognized by the human anti-Ri autoantibody is expressed in central but not peripheral nervous system neurons (1993) (43)
- Defects in translational regulation contributing to human cognitive and behavioral disease. (2011) (42)
- RNA regulation in neurologic disease and cancer. (2010) (42)
- A T cell receptor associated with naturally occurring human tumor immunity (2007) (41)
- Independent regulation by sodium butyrate of gonadotropin alpha gene expression and cell cycle progression in HeLa cells (1984) (41)
- A new cause of limbic encephalopathy. (2005) (41)
- Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory Neurons Regulates Cortical Development and Cerebellar Function (2019) (39)
- Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation. (2007) (39)
- Immune Escape via a Transient Gene Expression Program Enables Productive Replication of a Latent Pathogen. (2017) (38)
- Successful Targeted Therapy of Refractory Pediatric ETV6-NTRK3 Fusion-Positive Secretory Breast Carcinoma. (2017) (38)
- Cellular immune suppression in paraneoplastic neurologic syndromes targeting intracellular antigens. (2012) (38)
- Developing global insight into RNA regulation. (2006) (37)
- Sox21 is a repressor of neuronal differentiation and is antagonized by YB-1 (2004) (37)
- The Onconeural Antigen cdr2 Is a Novel APC/C Target that Acts in Mitosis to Regulate C-Myc Target Genes in Mammalian Tumor Cells (2010) (35)
- Elavl3 is essential for the maintenance of Purkinje neuron axons (2018) (34)
- The importance of defining the paraneoplastic neurologic disorders. (1999) (32)
- Comparing sequencing assays and human-machine analyses in actionable genomics for glioblastoma (2017) (32)
- A novel antineuronal antibody in stiff‐man syndrome (1993) (32)
- Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk (2021) (31)
- T cells targeting a neuronal paraneoplastic antigen mediate tumor rejection and trigger CNS autoimmunity with humoral activation (2014) (28)
- Determination and augmentation of RNA sequence specificity of the Nova K-homology domains. (2004) (27)
- Immunologic Complexity in Neurons (1998) (26)
- Tolerance to the Neuron-Specific Paraneoplastic HuD Antigen (2009) (25)
- A recurrent novel MGA–NUTM1 fusion identifies a new subtype of high-grade spindle cell sarcoma (2018) (24)
- The polymerase chain reaction: Application to nervous system disease (1993) (23)
- Harnessing Naturally Occurring Tumor Immunity: A Clinical Vaccine Trial in Prostate Cancer (2010) (23)
- Vaccine Breakthrough Infections with SARS-CoV-2 Variants. Reply. (2021) (22)
- Functional and mechanistic insights from genome-wide studies of splicing regulation in the brain. (2007) (22)
- A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ (2019) (22)
- Differential 3’ processing of specific transcripts expands regulatory and protein diversity across neuronal cell types (2018) (21)
- A destructive feedback loop mediated by CXCL10 in central nervous system inflammatory disease (2015) (21)
- Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens. (1997) (20)
- Microexons—Tiny but mighty (2015) (20)
- NOVA2 regulates neural circRNA biogenesis (2021) (19)
- RNA Logic in Time and Space (2002) (19)
- Dendritic cells loaded with FK506 kill T cells in an antigen-specific manner and prevent autoimmunity in vivo (2013) (19)
- cdr2‐Specific CTLs are detected in the blood of all patients with paraneoplastic cerebellar degeneration analyzed (2000) (19)
- Comprar Paraneoplastic Syndromes | MD, FAAN | 9780199772735 | Oxford University Press (2011) (18)
- Synthesis of phosphatidylinositol in rat liver microsomes is accompanied by the rapid formation of lysophosphatidylinositol. (1991) (18)
- Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes (2015) (18)
- Global mapping of miRNA-target interactions in cattle (Bos taurus) (2017) (17)
- Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons (2018) (16)
- The role of glycosylphosphoinositides in signal transduction. (1989) (16)
- Identification of targetable BRAF ΔN486_P490 variant by whole-genome sequencing leading to dabrafenib-induced remission of a BRAF-mutant pancreatic adenocarcinoma (2019) (16)
- Brainstem and Cerebellum (2010) (16)
- Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons (2018) (16)
- Supplemental Information Protein-RNA and Protein-Protein Recognition by Dual KH 1 / 2 Domains of the Neuronal Splicing Factor Nova-1 (2011) (16)
- Fatty acid remodelling of phosphatidylinositol under conditions of de novo synthesis in rat liver microsomes. (1991) (16)
- Supplemental Information Protein-RNA and Protein-Protein Recognition by Dual KH 1 / 2 Domains of the Neuronal Splicing Factor Nova-1 (2011) (16)
- The function of glycosyl phosphoinositides in hormone action. (1988) (15)
- Memory, Synaptic Translation, and…Prions? (2003) (15)
- AGO CLIP reveals an activated network for acute regulation of brain glutamate homeostasis after ischemic stroke (2018) (15)
- Coenzyme A-dependent, ATP-independent acylation of 2-acyl lysophosphatidylinositol in rat liver microsomes. (1991) (14)
- Novel patterns of complex structural variation revealed across thousands of cancer genome graphs (2019) (14)
- FMRP binding to a ranked subset of long genes is revealed by coupled CLIP and TRAP in specific neuronal cell types (2019) (12)
- YTHDC2 control of gametogenesis requires helicase activity but not m6A binding (2022) (12)
- Reversible diencephalic dysfunction (1993) (12)
- FMRP binding to a ranked subset of long genes is revealed by coupled CLIP and TRAP in specific neuronal cell types (2019) (12)
- Differential burden of rare protein truncating variants in Alzheimer's disease patients compared to centenarians. (2016) (12)
- Non-Neurologic Paraneoplastic Syndromes (2010) (11)
- FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons (2021) (11)
- mechanisms of disease Paraneoplastic Syndromes Involving the Nervous System (2003) (11)
- Ribosome rescue and neurodegeneration (2014) (10)
- Structure and expression of human placental hormone genes. (1986) (10)
- Patient-Driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel AKT1 Fusion-Driven Cancer. (2019) (10)
- Whole Genome Sequencing-Based Discovery of Structural Variants in Glioblastoma. (2018) (9)
- Role of glycosyl phosphoinositides in insulin action. (1988) (9)
- Whole-genome deep learning analysis reveals causal role of noncoding mutations in autism (2018) (8)
- Whole-genome deep learning analysis reveals causal role of noncoding mutations in autism (2018) (8)
- Ri/Nova gene‐associated paraneoplastic subacute motor neuronopathy (2013) (8)
- Proteolytic degradation and potential role of onconeural protein cdr2 in neurodegeneration (2016) (8)
- Mapping of In Vivo RNA-Binding Sites by Ultraviolet (UV)-Cross-Linking Immunoprecipitation (CLIP). (2018) (8)
- Mapping of In Vivo RNA-Binding Sites by Ultraviolet (UV)-Cross-Linking Immunoprecipitation (CLIP). (2018) (8)
- Excess ribosomal protein production unbalances translation in a model of Fragile X Syndrome (2022) (7)
- ZFP36 RNA-binding proteins restrain T-cell activation and anti-viral immunity (2018) (7)
- Autoimmune encephalopathy: The spectrum widens (2009) (7)
- NMDA receptor as a target in paraneoplastic encephalitis (2007) (7)
- Comprehensive Identification of mRNA Polyadenylation Sites by PAPERCLIP. (2017) (6)
- Immunoprecipitation and SDS-PAGE for Cross-Linking Immunoprecipitation (CLIP). (2018) (6)
- Dendritic cell vaccines containing lymphocytes produce improved immunogenicity in patients with cancer (2014) (6)
- The Genetic Control of Stoichiometry Underlying Autism. (2020) (6)
- Immunoprecipitation and SDS-PAGE for Cross-Linking Immunoprecipitation (CLIP). (2018) (6)
- Paraneoplastic Syndromes (Contemporary Neurology Series) (2011) (6)
- Sequencing and curation strategies for identifying candidate glioblastoma treatments (2019) (6)
- Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation (2017) (5)
- Tumor immunity in small-cell lung cancer. (2004) (5)
- Neuronal Signaling through Alternative Splicing: Some Exons CaRRE... (2001) (5)
- Ultraviolet (UV) Cross-Linking of Live Cells, Lysate Preparation, and RNase Titration for Cross-Linking Immunoprecipitation (CLIP). (2018) (4)
- Erratum: Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis (2016) (4)
- Turkey must end violent response to protests. (2013) (4)
- DRUL for school: Opening Pre-K with safe, simple, sensitive saliva testing for SARS-CoV-2 (2021) (4)
- Erratum: Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis (2016) (4)
- Ultraviolet (UV) Cross-Linking of Live Cells, Lysate Preparation, and RNase Titration for Cross-Linking Immunoprecipitation (CLIP). (2018) (4)
- De novo indels within introns contribute to ASD incidence (2017) (3)
- 3'-Linker Ligation and Size Selection by SDS-PAGE for Cross-Linking Immunoprecipitation (CLIP). (2018) (3)
- Whole genome sequencing of pharmacogenetic drug response in racially and ethnically diverse children with asthma (2017) (3)
- T cells presenting viral antigens or autoantigens induce cytotoxic T cell anergy. (2017) (3)
- Isolation of the RNA Cross-Linking Immunoprecipitation (CLIP) Tags, 5'-Linker Ligation, Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Amplification, and Sequencing. (2018) (3)
- N6-methyladenosine dynamics during early vertebrate embryogenesis (2019) (3)
- Isolation of the RNA Cross-Linking Immunoprecipitation (CLIP) Tags, 5'-Linker Ligation, Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Amplification, and Sequencing. (2018) (3)
- 3'-Linker Ligation and Size Selection by SDS-PAGE for Cross-Linking Immunoprecipitation (CLIP). (2018) (3)
- Neuron-specific cTag-CLIP reveals cell-specific diversity of functional RNA regulation in the brain (2018) (3)
- The maintenance of Purkinje axons by an RNA-binding protein HuC in adult cerebellum (2011) (2)
- Author response: NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord (2016) (2)
- The maintenance of Purkinje axons by HuC in adult cerebellum (2010) (2)
- AGO HITS-CLIP reveals distinct miRNA regulation of white and brown adipose tissue identity (2021) (2)
- Dorsal Root Ganglia and Peripheral Nerves (2010) (2)
- Author response: ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity (2018) (2)
- RNA regulation in Neurodegeneration and Cancer (2011) (1)
- FMRP association with and regulation of Fragile X granules exhibit circuit-dependent requirements for the KH2 RNA binding domain (2018) (1)
- Paraneoplastic Antinuclear and Antinucleolar Antibodies (2010) (1)
- The role of CSF CXCL10 in paraneoplastic neurologic disorders (2016) (1)
- MicroRNA-218 instructs proper assembly of hippocampal networks (2022) (1)
- Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons (2018) (1)
- Author response: NOVA2-mediated RNA regulation is required for axonal pathfinding during development (2016) (1)
- Clinical Findings, Diagnosis, Treatment, and Prognosis (2010) (1)
- Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing (2019) (1)
- Hematologic Malignancies and Miscellaneous Solid Tumors (2010) (1)
- Abstract 4497: NYGC glioblastoma clinical outcomes pilot study: Discovering therapeutic potential in glioblastoma through integrative genomics (2016) (1)
- Author response: Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain (2015) (1)
- Anti-Retinal and Optic Nerve Antibodies (2010) (1)
- Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons (2018) (1)
- Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk (2019) (1)
- Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis (2023) (1)
- Neuromuscular Junction and Muscle (2010) (0)
- Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN- (cid:1) / (cid:2) on antigen cross-presentation (2007) (0)
- Global mapping of miRNA-target interactions in cattle (Bos taurus) (2017) (0)
- Breast, Gynecologic, and Testicular Cancers (2010) (0)
- RBPS IN NEURONS AND NEUROLOGIC DISEASE RNA has greater complexity than DNA (2006) (0)
- Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, cesium bound form. (2015) (0)
- by a Specific Protein CLIP (Cross-Linking and Immunoprecipitation) Identification of RNAs Bound (2014) (0)
- Definitions, Classification, History, Epidemiology, and Importance (2010) (0)
- Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA. (2015) (0)
- Independent Regulation bySodiumButyrate ofGonadotropin Alpha GeneExpression andCellCycle Progression inHeLaCells (1984) (0)
- Corrigendum: CLIP (Cross-Linking and Immunoprecipitation) Identification of RNAs Bound by a Specific Protein. (2022) (0)
- Context specific regulation of microRNA targets in the immune system (P1142) (2013) (0)
- Author response: Dendritic cells loaded with FK506 kill T cells in an antigen-specific manner and prevent autoimmunity in vivo (2012) (0)
- Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, cesium bound form. (2015) (0)
- Author response: FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons (2021) (0)
- Genome-wide landscape of RNA-binding protein dysregulation reveals a major impact on psychiatric disorder risk (2020) (0)
- Correction to: Sequencing and curation strategies for identifying candidate glioblastoma treatments (2019) (0)
- RNA Duplex-Quadruplex Junction Complex with FMRP RGG peptide (2011) (0)
- CHAPTER 16Paraneoplastic Syndromes (2004) (0)
- Cerebral Hemisphere Syndromes (2010) (0)
- PRIME Cells Predicting Rheumatoid Arthritis Flares. Reply. (2020) (0)
- RNA regulation and modular control of the neuronal synapse (2006) (0)
- Advances in Brief cdr 2 , a Target Antigen of Naturally Occurring Human Tumor Immunity , Is Widely Expressed in Gynecological Tumors 1 (2000) (0)
- Crystal structure (I) of Nova-1 KH1/KH2 domain tandem with 25 nt RNA hairpin (2006) (0)
- Windows Into Neuronal Function and Tumor Immunity (2016) (0)
- Synaptic and Channel Antibodies (2010) (0)
- Correction to: Sequencing and curation strategies for identifying candidate glioblastoma treatments (2019) (0)
- A master regulatory network restoring brain glutamate homeostasis is coordinately activated in stroke (2018) (0)
- Excess ribosomal protein production unbalances translation in Fragile X Syndrome (2022) (0)
- Localization and local translation of mRNA at synapses: some observations and paradoxes. (2015) (0)
- Crystal structure (I) of Nova-1 KH1/KH2 domain tandem with 25 nt RNA hairpin (2006) (0)
- NOVA1 acts on Impact to regulate hypothalamic function and translation in inhibitory neurons. (2023) (0)
- Author response: FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory (2019) (0)
- Have you seen ? Microexons — Tiny but mighty (2015) (0)
- Mapping and characterization of structural variation in 17,795 human genomes (2020) (0)
- Author response: NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure (2012) (0)
- PNAS Plus Significance Statements (2015) (0)
- F.16. Identification of HuD-specific CD8+ T Cells in Paraneoplastic Neurologic Degeneration Patients with Tumor Immunity and Autoimmunity (2008) (0)
- Author response: Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer (2014) (0)
- Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, iridium hexammine bound form. (2015) (0)
- Advances in Brief cdr 2 , a Target Antigen of Naturally Occurring Human Tumor Immunity , Is Widely Expressed in Gynecological Tumors 1 (2000) (0)
- Identifying RNA-binding Proteins as a Novel Class of Therapeutic Targets in Glioblastoma Cancer Stem-Like Cells (2016) (0)
- DeepSEA and Seqweaver: Deep learning frameworks for the identification of de novo disease-causing mutations in noncoding sequences (2019) (0)
- Spinal Cord Syndromes (2010) (0)
- CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN (2000) (0)
- Dendritic cell vaccines containing lymphocytes produce improved immunogenicity in patients with cancer (2014) (0)
- Breast Tumor Immunity in the Paraneoplastic Neurologic Disorders. (1995) (0)
- Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, iridium hexammine bound form. (2015) (0)
- ReviewRNA Logic in Time and Space translation initiation for most mRNAs ( IRES-dependent (2002) (0)
- The Future of CLIP (2018) (0)
- When Science Is a Family Tradition (2015) (0)
- Ruggiu Agrin&Nova Supplementary PNAS2009 (2013) (0)
- Sequencing and curation strategies for identifying candidate glioblastoma treatments (2019) (0)
- Chaolin Zhang and Its Combinatorial Controls Integrative Modeling Defines the Nova Splicing-Regulatory Network (2013) (0)
- Author response: FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory (2019) (0)
- RNA Duplex-Quadruplex Junction Complex with FMRP RGG peptide (2011) (0)
- Elavl3 is essential for the maintenance of Purkinje neuron axons (2018) (0)
- Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA. (2015) (0)
- Reply (2016) (0)
- AGO HITS-CLIP in Adipose Tissue Reveals miR-29 as a Post-Transcriptional Regulator of Leptin (2020) (0)
- Abstract 4498: RNA-Seq in the NYGC GBM Clinical Outcomes Pilot Study (2016) (0)
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