Robert Bittman

Q: What Schools Are Affiliated With Robert Bittman

Robert Bittman is affiliated with the following schools: Queens College, City University of New York, University of Strathclyde, CUNY Graduate Center, University of Manitoba, University of Groningen, Technical University of Munich, University of Tennessee Health Science Center, Åbo Akademi University

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Robert Bittman

Chemistry

#3069

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#4055

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Physical Chemistry

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#442

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Organic Chemistry

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#555

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chemistry Degrees

Robert Bittman

Biology

#8687

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#11804

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Biochemistry

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#1395

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Chemistry
Biology

Robert Bittman's Degrees

PhD Chemistry University of California, Berkeley
Bachelors Chemistry Stanford University

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Robert Bittman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Effect of the Structure of Natural Sterols and Sphingolipids on the Formation of Ordered Sphingolipid/Sterol Domains (Rafts) (2001) (516)
Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions. (1999) (433)
Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis. (1995) (347)
Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. (2013) (261)
Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses (2011) (257)
Crystal Structure of the Mycobacterium tuberculosis Enoyl-ACP Reductase, InhA, in Complex with NAD+ and a C16 Fatty Acyl Substrate* (1999) (250)
Selective caveolin-1-dependent endocytosis of glycosphingolipids. (2003) (244)
BODIPY‐Cholesterol: A New Tool to Visualize Sterol Trafficking in Living Cells and Organisms (2008) (231)
Lysophosphatidic Acid Induces Neointima Formation Through PPARγ Activation (2004) (214)
Endothelial disruptive proinflammatory effects of nicotine and e-cigarette vapor exposures. (2015) (204)
Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan for Malarial Enoyl Acyl Carrier Protein Reductase* (2002) (201)
PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells. (2013) (193)
First synthesis of free cholesterol-BODIPY conjugates. (2006) (177)
FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells (2010) (176)
Correlated fluorescence-atomic force microscopy of membrane domains: structure of fluorescence probes determines lipid localization. (2006) (175)
The Immunomodulator FTY720 Has a Direct Cytoprotective Effect in Oligodendrocyte Progenitors (2007) (173)
A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol (2011) (171)
THE BINDING OF NICOTINAMIDE-ADENINE DINUCLEOTIDE TO YEAST D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE: TEMPERATURE-JUMP RELAXATION STUDIES ON THE MECHANISM OF AN ALLOSTERIC ENZYME* (1966) (155)
Interaction of cholesterol with sphingomyelin in monolayers and vesicles. (1994) (155)
Carba Analogs of Cyclic Phosphatidic Acid Are Selective Inhibitors of Autotaxin and Cancer Cell Invasion and Metastasis* (2006) (152)
FTY720 Inhibits Ceramide Synthases and Up-regulates Dihydrosphingosine 1-Phosphate Formation in Human Lung Endothelial Cells* (2009) (151)
The phospholipid-cholesterol interaction. Kinetics of water permeability in liposomes. (1972) (149)
Short-chain ceramide-1-phosphates are novel stimulators of DNA synthesis and cell division: antagonism by cell-permeable ceramides. (1995) (148)
NADH Dehydrogenase Defects Confer Isoniazid Resistance and Conditional Lethality in Mycobacterium smegmatis (1998) (148)
Bacterial lipopolysaccharide has structural similarity to ceramide and stimulates ceramide-activated protein kinase in myeloid cells. (1994) (147)
Low-pH-Dependent Fusion of Sindbis Virus with Receptor-Free Cholesterol- and Sphingolipid-Containing Liposomes (1999) (147)
Induction of Apoptosis and Potentiation of Ceramide-mediated Cytotoxicity by Sphingoid Bases in Human Myeloid Leukemia Cells (*) (1996) (146)
Cyclic Sulfites and Cyclic Sulfates in Organic Synthesis (2000) (135)
Erythrocytes serve as a reservoir for cellular and extracellular sphingosine 1‐phosphate (2010) (129)
Intracellular Generation of Sphingosine 1-Phosphate in Human Lung Endothelial Cells (2007) (129)
Novel Ceramide Analogs as Potential Chemotherapeutic Agents in Breast Cancer (2004) (123)
FTY720 Analogues as Sphingosine Kinase 1 Inhibitors (2011) (121)
Substrate recognition by ceramide-activated protein kinase. Evidence that kinase activity is proline-directed. (1993) (118)
Studies of the binding of ethidium bromide to transfer ribonucleic acid: absorption, fluorescence, ultracentrifugation and kinetic investigations. (1969) (117)
Use of Bodipy-labeled sphingolipid and cholesterol analogs to examine membrane microdomains in cells (2008) (116)
Raftlike mixtures of sphingomyelin and cholesterol investigated by solid-state 2H NMR spectroscopy. (2008) (115)
Ceramide Synthesis Is Modulated by the Sphingosine Analog FTY720 via a Mixture of Uncompetitive and Noncompetitive Inhibition in an Acyl-CoA Chain Length-de pend ent Manner* (2009) (114)
Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs. (2014) (112)
Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury. (2013) (109)
Interactions of very long-chain saturated fatty acids with serum albumin DOI 10.1194/jlr.M200041-JLR200 (2002) (108)
The Hedgehog Receptor Patched Is Involved in Cholesterol Transport (2011) (107)
Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies. (2013) (104)
A Single Subset of Dendritic Cells Controls the Cytokine Bias of Natural Killer T Cell Responses to Diverse Glycolipid Antigens (2014) (102)
Movement of cholesterol between vesicles prepared with different phospholipids or sizes. (1985) (101)
An improved synthesis of 6-O-monotosyl-6-deoxy-β-cyclodextrin (1998) (99)
Equilibrium binding of amphotericin B and its methyl ester and borate complex to sterols. (1982) (97)
Adaptation of Alphaviruses to Heparan Sulfate: Interaction of Sindbis and Semliki Forest Viruses with Liposomes Containing Lipid-Conjugated Heparin (2002) (97)
Membrane fluidity and lipid order in ternary giant unilamellar vesicles using a new bodipy-cholesterol derivative. (2009) (97)
The inhibition of cell signaling pathways by antitumor ether lipids. (1998) (97)
Role of ORPs in Sterol Transport from Plasma Membrane to ER and Lipid Droplets in Mammalian Cells (2011) (96)
Effect of ceramide N-acyl chain and polar headgroup structure on the properties of ordered lipid domains (lipid rafts). (2007) (94)
Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling. (1998) (93)
Role of ceramide in membrane protein organization investigated by combined AFM and FCS. (2008) (93)
LDL cholesterol recycles to the plasma membrane via a Rab8a-Myosin5b-actin-dependent membrane transport route. (2013) (92)
Sphingosine kinase inhibitors and cancer: seeking the golden sword of Hercules. (2011) (90)
Different Residues Mediate Recognition of 1-O-Oleyllysophosphatidic Acid and Rosiglitazone in the Ligand Binding Domain of Peroxisome Proliferator-activated Receptor γ* (2006) (89)
Sphingolipid and Cholesterol Dependence of Alphavirus Membrane Fusion (2002) (89)
(R)-FTY720 methyl ether is a specific sphingosine kinase 2 inhibitor: Effect on sphingosine kinase 2 expression in HEK 293 cells and actin rearrangement and survival of MCF-7 breast cancer cells. (2011) (88)
The 4,5-double bond of ceramide regulates its dipole potential, elastic properties, and packing behavior. (2004) (85)
Docosahexaenoic acid enhances segregation of lipids between : 2H-NMR study. (2008) (85)
The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner. (2011) (81)
Interaction of cholesterol with sphingomyelin in bilayer membranes: evidence that the hydroxy group of sphingomyelin does not modulate the rate of cholesterol exchange between vesicles. (1991) (80)
Sterol effects and sites of sterol accumulation in Caenorhabditis elegans: developmental requirement for 4alpha-methyl sterols. (2003) (79)
Synthesis and spectral properties of cholesterol- and FTY720-containing boron dipyrromethene dyes. (2007) (77)
A stereocontrolled, efficient synthetic route to bioactive sphingolipids: synthesis of phytosphingosine and phytoceramides from unsaturated ester precursors via cyclic sulfate intermediates. (2000) (76)
Coupling of Cholesterol and Cone-shaped Lipids in Bilayers Augments Membrane Permeabilization by the Cholesterol-specific Toxins Streptolysin O and Vibrio cholerae Cytolysin* (2001) (75)
Stereospecific induction of apoptosis in U937 cells by N-octanoyl-sphingosine stereoisomers and N-octyl-sphingosine. The ceramide amide group is not required for apoptosis. (1996) (74)
Chemopreventive sphingadienes downregulate Wnt signaling via a PP2A/Akt/GSK3β pathway in colon cancer. (2012) (74)
Fluorescence studies of the binding of the polyene antibiotics filipin 3, amphotericin B, nystatin, and lagosin to cholesterol. (1972) (73)
Antitumor ether lipids and alkylphosphocholines (1994) (72)
NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation (2013) (70)
Interaction of cholesterol with synthetic sphingomyelin derivatives in mixed monolayers. (1991) (69)
The structural specificity of lecithin for activation of purified D-beta-hydroxybutyrate apodehydrogenase. (1979) (67)
Rates of spontaneous exchange of synthetic radiolabeled sterols between lipid vesicles. (1992) (66)
Synthetic Analogs of FTY720 [2-Amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol] Differentially Regulate Pulmonary Vascular Permeability in Vivo and in Vitro (2009) (64)
Ceramide is a competitive inhibitor of diacylglycerol kinase in vitro and in intact human leukemia (HL-60) cells. (1992) (62)
Antiviral activity of human lactoferrin: inhibition of alphavirus interaction with heparan sulfate. (2005) (61)
Interaction of filipin 3 and amphotericin B with lecithin-sterol vesicles and cellular membranes. Spectral and electron microscope studies. (1974) (61)
N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids are selective competitive antagonists of the lysophosphatidic acid receptors. (1996) (59)
Role of sphingolipids in murine radiation‐induced lung injury: protection by sphingosine 1‐phosphate analogs (2011) (58)
The Raft-Promoting Property of Virion-Associated Cholesterol, but Not the Presence of Virion-Associated Brij 98 Rafts, Is a Determinant of Human Immunodeficiency Virus Type 1 Infectivity (2004) (57)
Sphingolipids activate membrane fusion of Semliki Forest virus in a stereospecific manner. (1995) (57)
Novel sphingosine-containing analogues selectively inhibit sphingosine kinase (SK) isozymes, induce SK1 proteasomal degradation and reduce DNA synthesis in human pulmonary arterial smooth muscle cells. (2013) (56)
Regiospecific opening of glycidyl derivatives mediated by boron trifluoride. Asymmetric synthesis of ether-linked phospholipids (1989) (56)
Amot Recognizes a Juxtanuclear Endocytic Recycling Compartment via a Novel Lipid Binding Domain* (2010) (56)
Caveolar Endocytosis and Microdomain Association of a Glycosphingolipid Analog Is Dependent on Its Sphingosine Stereochemistry* (2006) (55)
Natural sphingadienes inhibit Akt-dependent signaling and prevent intestinal tumorigenesis. (2009) (55)
Quantitative assessment of sterol traffic in living cells by dual labeling with dehydroergosterol and BODIPY-cholesterol. (2011) (55)
(S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity. (2010) (54)
Sphingolipid-dependent fusion of Semliki Forest virus with cholesterol-containing liposomes requires both the 3-hydroxyl group and the double bond of the sphingolipid backbone (1995) (54)
Plasma gelsolin modulates cellular response to sphingosine 1-phosphate. (2010) (54)
Inhibition of caveolar uptake, SV40 infection, and β1-integrin signaling by a nonnatural glycosphingolipid stereoisomer (2007) (54)
Fusion of Semliki Forest virus with cholesterol-containing liposomes at low pH: a specific requirement for sphingolipids. (1995) (53)
Membrane orientation and lateral diffusion of BODIPY-cholesterol as a function of probe structure. (2013) (53)
Cholesterol : its functions and metabolism in biology and medicine (1997) (53)
NKT TCR Recognition of CD1d-α-C-Galactosylceramide (2011) (53)
Effects of sterols on permeability and phase transitions of bilayers from phosphatidylcholines lacking acyl groups. (1981) (53)
Improved syntheses of ethyl α-(bromomethyl)acrylate and 2-methylene-1,3-propanediol via ethyl α-(hydroxymethyl)acrylate (1994) (52)
The effect of side-chain analogues of cholesterol on the thermotropic phase behavior of 1-stearoyl-2-oleoylphosphatidylcholine bilayers: a differential scanning calorimetric study. (1996) (52)
Differential scanning calorimetric study of the effect of sterol side chain length and structure on dipalmitoylphosphatidylcholine thermotropic phase behavior. (1995) (52)
Structure and lipid interaction of N-palmitoylsphingomyelin in bilayer membranes as revealed by 2H-NMR spectroscopy. (2006) (52)
Dual inhibition of mycobacterial fatty acid biosynthesis and degradation by 2-alkynoic acids. (2006) (52)
Influence of cholesterol on bilayers of ester- and ether-linked phospholipids. Permeability and 13C-nuclear magnetic resonance measurements. (1984) (51)
The role of sphingosine 1-phosphate in inflammation and cancer. (2014) (50)
FTY720 Stimulates 27-Hydroxycholesterol Production and Confers Atheroprotective Effects in Human Primary Macrophages (2010) (50)
The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells. (2013) (49)
Dissociation kinetics and equilibrium binding properties of polyene antibiotic complexes with phosphatidylcholine/sterol vesicles. (1984) (48)
Kinetics of cholesterol and phospholipid exchange between Mycoplasma gallisepticum cells and lipid vesicles. Alterations in membrane cholesterol and protein content. (1984) (48)
Vibrational assignment of the sn‐1 and sn‐2 chain carbonyl stretching modes of membrane phospholipids (1982) (48)
Permeability properties of sterol-containing liposomes from analogues of phosphatidylcholine lacking acyl groups. (1979) (48)
Interaction of the Vibrio cholerae cytolysin (VCC) with cholesterol, some cholesterol esters, and cholesterol derivatives: a TEM study. (2002) (47)
Has nature designed the cholesterol side chain for optimal interaction with phospholipids? (1997) (47)
Cholesterol's aliphatic side chain modulates membrane properties. (2013) (47)
Enzymatic Oxidation of Cholesterol: Properties and Functional Effects of Cholestenone in Cell Membranes (2014) (47)
1-O-octadecyl-2-O-methyl-glycerophosphocholine inhibits the transduction of growth signals via the MAPK cascade in cultured MCF-7 cells. (1996) (46)
Ceramide-1-phosphate inhibits cigarette smoke-induced airway inflammation (2015) (46)
Synthesis and Evaluation of an α‐C‐Galactosylceramide Analogue that Induces Th1‐biased Responses in Human Natural Killer T Cells (2006) (46)
Cholesterol distribution between the two halves of the lipid bilayer of human erythrocyte ghost membranes. (1978) (45)
Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier (2016) (45)
Synthesis of selective inhibitors of sphingosine kinase 1. (2013) (45)
Glycidyl derivatives as chiral C3 synthons. Ring opening catalyzed by boron trifluoride etherate (1989) (45)
Bax and Bcl-xL exert their regulation on different sites of the ceramide channel. (2012) (45)
Characterization of sphingosine-1-phosphate lyase activity by electrospray ionization-liquid chromatography/tandem mass spectrometry quantitation of (2E)-hexadecenal. (2011) (44)
Hydrophilic cholesterol-binding molecular imprinted polymers (2001) (44)
Rates of amphotericin B and filipin association with sterols. A study of changes in sterol structure and phospholipid composition of vesicles. (1985) (44)
Distribution of cholesterol between the outer and inner halves of the lipid bilayer of mycoplasma cell membranes. (1976) (44)
Decreases in rates of lipid exchange between Mycoplasma gallisepticum cells and unilamellar vesicles by incorporation of sphingomyelin. (1984) (43)
Interaction of sphingomyelinase with sphingomyelin analogs modified at the C-1 and C-3 positions of the sphingosine backbone. (1995) (43)
LAPTM4B facilitates late endosomal ceramide export to control cell death pathways. (2015) (43)
Chiral vinylphosphonate and phosphonate analogues of the immunosuppressive agent FTY720. (2009) (42)
CD2 rocking modes as quantitative infrared probes of one-, two-, and three-bond conformational disorder in dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylcholine/cholesterol mixtures. (1991) (42)
Ceramide channels: influence of molecular structure on channel formation in membranes. (2012) (42)
The stoichiometry of A23187- and X537A-mediated calcium ion transport across lipid bilayers. (1984) (41)
Structural requirements of sphingosylphosphocholine and sphingosine-1-phosphate for stimulation of activator protein-1 activity. (1996) (41)
First asymmetric synthesis of 6-hydroxy-4-sphingenine-containing ceramides. Use of chiral propargylic alcohols to prepare a lipid found in human skin. (2003) (41)
Novel ceramide analogues display selective cytotoxicity in drug-resistant breast tumor cell lines compared to normal breast epithelial cells. (2003) (40)
Caged ceramide 1-phosphate analogues: synthesis and properties. (2009) (40)
Inhibition kinetics and regulation of sphingosine kinase 1 expression in prostate cancer cells: functional differences between sphingosine kinase 1a and 1b. (2012) (40)
FTY720 (S)-Phosphonate Preserves Sphingosine 1-Phosphate Receptor 1 Expression and Exhibits Superior Barrier Protection to FTY720 in Acute Lung Injury (2014) (40)
Stereoselective preparation of ceramide and its skeleton backbone modified analogues via cyclic thionocarbonate intermediates derived by catalytic asymmetric dihydroxylation of alpha,beta-unsaturated ester precursors. (2000) (40)
Kinetics of association of amphotericin B with vesicles. (1977) (40)
Lateral domain formation in cholesterol/phospholipid monolayers as affected by the sterol side chain conformation. (1995) (40)
Synthesis and growth inhibitory properties of glucosamine-derived glycerolipids. (2001) (39)
Cholesterol interacts with lactosyl and maltosyl cerebrosides but not with glucosyl or galactosyl cerebrosides in mixed monolayers. (1993) (39)
Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate. (2012) (39)
Behavior of a photoactivatable analog of cholesterol, 6‐photocholesterol, in model membranes (2002) (39)
Interaction of mammalian seminal plasma protein PDC-109 with cholesterol: implications for a putative CRAC domain. (2010) (39)
Sphingosine Interaction with Acidic Leucine-rich Nuclear Phosphoprotein-32A (ANP32A) Regulates PP2A Activity and Cyclooxygenase (COX)-2 Expression in Human Endothelial Cells* (2010) (39)
Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics (2014) (38)
Synthesis of ceramide analogues having the C(4)-C(5) bond of the long-chain base as part of an aromatic or heteroaromatic system. (2000) (38)
Structure–Activity Relationships and Molecular Modeling of Sphingosine Kinase Inhibitors (2013) (38)
Visualization of lipid metabolism in the zebrafish intestine reveals a relationship between NPC1L1-mediated cholesterol uptake and dietary fatty acid. (2012) (37)
Combined light and electron microscopy using diaminobenzidine photooxidation to monitor trafficking of lipids derived from lipoprotein particles. (2011) (37)
Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrate. (2009) (37)
Stopped-flow kinetic and equilibrium studies of filipin 3 binding to sterols. (1974) (37)
Stopped-flow kinetic studies of actinomycin binding to DNAs. (1975) (36)
Synthesis of l-lyxo-phytosphingosine and its 1-phosphonate analogue using a threitol acetal synthon. (2004) (36)
Effect of sterol side-chain structure on sterol-phosphatidylcholine interactions in monolayers and small unilamellar vesicles. (1994) (36)
Comparison of the capacity of beta-cyclodextrin derivatives and cyclophanes to shuttle cholesterol between cells and serum lipoproteins. (1999) (35)
An efficient stereocontrolled route to both enantiomers of platelet activating factor and analogs with long-chain esters at C-2: saturated and unsaturated ether glycerolipids by opening of glycidyl arenesulfonates (1989) (35)
Cholesterol distribution and movement in the Mycoplasma gallisepticum cell membrane. (1978) (35)
Interactions of cholesterol and synthetic sterols with phosphatidylcholines as deduced from infrared CH2 wagging progression intensities (1993) (34)
Identification and characterization by electrospray mass spectrometry of endogenous Drosophila sphingadienes Published, JLR Papers in Press, December 21, 2007. (2008) (34)
Organization of fluorescent cholesterol analogs in lipid bilayers - lessons from cyclodextrin extraction. (2013) (34)
Docosahexaenoic Acid Enhances Segregation of Lipids between Raft and Nonraft Domains : 2 H-NMR Study (2008) (34)
Inflammation in the Pathogenesis of Chronic Diseases (2007) (33)
Gramicidin channel function does not depend on phospholipid chirality. (1995) (33)
Synthesis of C-glycoside analogues of α-galactosylceramide via linear allylic C-H oxidation and allyl cyanate to isocyanate rearrangement. (2012) (33)
Hydrolysis of short acyl chain inositol lipids by phospholipase C-delta 1. (1993) (33)
Synthesis of New Trans Double-Bond Sphingolipid Analogues: Δ4,6 and Δ6 Ceramides (2002) (32)
SYNTHESIS OF PLASMALOGEN VIA 2,3-BIS-O-(4'-METHOXYBENZYL)-SN-GLYCEROL (1999) (32)
Molecular Interaction and Lateral Domain Formation in Monolayers Containing Cholesterol and Phosphatidylcholines with Acyl- or Alkyl-Linked C16 Chains (1996) (32)
Stereochemical properties of lysophosphatidic acid receptor activation and metabolism. (2002) (32)
Effects of sterol structure and exogenous lipids on the transbilayer distribution of sterols in the membrane of Mycoplasma capricolum. (1981) (32)
Inhibition of protein kinase C by ether-linked lipids is not correlated with their antineoplastic activity on WEHI-3B and R6X-B15 cells. (1992) (32)
Sphingomyelin Modulates the Transbilayer Distribution of Galactosylceramide in Phospholipid Membranes* 210 (2002) (32)
Ceramide 1-phosphate stimulates glucose uptake in macrophages. (2010) (32)
Synthesis of immunostimulatory alpha-C-galactosylceramide glycolipids via Sonogashira coupling, asymmetric epoxidation, and trichloroacetimidate-mediated epoxide opening. (2010) (31)
The critical micelle concentrations of lysophosphatidic acid and sphingosylphosphorylcholine. (2004) (31)
Fusion of alphaviruses with liposomes is a non‐leaky process (2002) (30)
Inhibitors of lipid phosphatidate receptors: N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids. (1996) (30)
6A‐O‐p‐Toluenesulfonyl‐β‐Cyclodextrin (2003) (30)
Uptake, transbilayer distribution, and movement of cholesterol in growing Mycoplasma capricolum cells. (1978) (30)
Hits of a High-Throughput Screen Identify the Hydrophobic Pocket of Autotaxin/Lysophospholipase D As an Inhibitory Surface (2013) (30)
Distribution and movement of sterols with different side chain structures between the two leaflets of the membrane bilayer of mycoplasma cells. (1984) (29)
Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics (2015) (29)
Improving Mycobacterium bovis Bacillus Calmette-Guèrin as a Vaccine Delivery Vector for Viral Antigens by Incorporation of Glycolipid Activators of NKT Cells (2014) (29)
Convergent C-glycolipid synthesis via the Ramberg-Bäcklund reaction: active antiproliferative glycolipids. (1999) (28)
Intrinsic Cytotoxicity and Chemomodulatory Actions of Novel Phenethylisothiocyanate Sphingoid Base Derivatives in HL-60 Human Promyelocytic Leukemia Cells (2004) (28)
Tracking peptide-membrane interactions: insights from in situ coupled confocal-atomic force microscopy imaging of NAP-22 peptide insertion and assembly. (2006) (28)
The sphingolipid degradation product trans-2-hexadecenal forms adducts with DNA. (2012) (28)
Binary mixtures of saturated and unsaturated mixed-chain phosphatidylcholine. A differential scanning calorimetry study. (1989) (28)
PE2 Cleavage Mutants of Sindbis Virus: Correlation between Viral Infectivity and pH-Dependent Membrane Fusion Activation of the Spike Heterodimer (2001) (28)
Molecular features of phospholipids that affect glycolipid transfer protein-mediated galactosylceramide transfer between vesicles. (2006) (27)
The 3-hydroxy group and 4,5-trans double bond of sphingomyelin are essential for modulation of galactosylceramide transmembrane asymmetry. (2005) (27)
Magic-angle spinning NMR studies of molecular organization in multibilayers formed by 1-octadecanoyl-2-decanoyl-sn-glycero-3-phosphocholine. (1990) (27)
A new tool to assess ceramide bioactivity: 6-bromo-7-hydroxycoumarinyl-caged ceramide. (2011) (27)
Lysophosphatidic acid and lipopolysaccharide bind to the PIP2-binding domain of gelsolin. (2006) (27)
Facile diacylation of glycidyl tosylate. Chiral synthesis of symmetric-chain glycerophospholipids (1988) (27)
The 2003 ASBMB-Avanti Award in Lipids Address: Applications of novel synthetic lipids to biological problems. (2004) (27)
HDL particles incorporate into lipid bilayers – a combined AFM and single molecule fluorescence microscopy study (2017) (27)
Sterol side chain length and structure affect the clearance of chylomicron-like lipid emulsions in rats and mice. (1998) (26)
Total synthesis of two photoactivatable analogues of the growth-factor-like mediator sphingosine 1-phosphate: differential interaction with protein targets. (2003) (26)
DHA Modifies the Size and Composition of Raftlike Domains: A Solid-State 2H NMR Study. (2018) (25)
Tracking Sphingosine Metabolism and Transport in Sphingolipidoses: NPC1 Deficiency as a Test Case (2012) (25)
Synthesis and growth inhibitory properties of glycosides of 1-O-hexadecyl-2-O-methyl-sn-glycerol, analogs of the antitumor ether lipid ET-18-OCH3 (edelfosine). (1996) (25)
Sphingosine kinase 2 prevents the nuclear translocation of sphingosine 1-phosphate receptor-2 and tyrosine 416 phosphorylated c-Src and increases estrogen receptor negative MDA-MB-231 breast cancer cell growth: The role of sphingosine 1-phosphate receptor-4. (2014) (25)
A glycosylated antitumor ether lipid kills cells via paraptosis-like cell death. (2009) (25)
Sphingosine‐1‐phosphate and the immunosuppressant, FTY720‐phosphate, regulate detrusor muscle tone (2007) (24)
Effects of Filipin on the Structure and Biological Activity of Enveloped Viruses (1977) (24)
Determination of cholesterol asymmetry by rapid kinetics of filipin-cholesterol association: effect of modification in lipids and proteins. (1981) (24)
Stereochemistry of the primary carbon. XVI. Optically active 1-butanol-1-d by hydroboration (1967) (24)
Junctional complex and focal adhesion rearrangement mediates pulmonary endothelial barrier enhancement by FTY720 S-phosphonate. (2015) (24)
An efficient preparation of isosteric phosphonate analogues of sphingolipids by opening of oxirane and cyclic sulfamidate intermediates with alpha-lithiated alkylphosphonic esters. (2004) (24)
1-O-Hexadecyl-2-O-methyl-3-O-(2'-acetamido-2'-deoxy-∃-D-glucopyranosyl)-sn-glycerol (Gln) induces cell death with more autophagosomes which is autophagy-independent (2009) (24)
Channeling of a beta-oxidation intermediate on the large subunit of the fatty acid oxidation complex from Escherichia coli. (1985) (24)
Phosphatidic acid inhibits ceramide 1-phosphate-stimulated macrophage migration. (2014) (24)
Synthesis and antineoplastic properties of ether-linked thioglycolipids. (1990) (24)
Partially deuterated phospholipids as IR structure probes of conformational order in bulk and monolayer phases (1996) (24)
Osmotic behavior of liposomes of phosphatidylcholine and phosphatidylsulfocholine as a function of lipid concentration (1981) (23)
Synthesis of DL-2,3-diacyloxypropylphosphonyl-cholines from DL-2,3-diacyloxyiodopropanes. (1976) (23)
Regioselective and Stereospecific Azidation of 1,2- and 1,3-Diols by Azidotrimethylsilane via a Mitsunobu Reaction (1999) (23)
The antitumor ether lipid 1-Q-octadecyl-2-O-methyl-rac-glycerophosphocholine (ET-18-OCH3) inhibits the association between Ras and Raf-1. (2003) (23)
Synthesis and growth inhibitory activity of chiral 5-hydroxy-2-N-acyl-(3E)-sphingenines: ceramides with an unusual sphingoid backbone. (2003) (23)
Synthesis of Sphingomyelin and Ceramide 1-Phosphate from Ceramide without Protection of the Allylic Hydroxyl Group (1994) (22)
Enantioselective synthesis of a novel trans double bond ceramide analogue via catalytic asymmetric dihydroxylation of an enyne. The role of the trans double bond of ceramide in the fusion of semliki forest virus with target membranes (1999) (22)
Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan for Malarial Enoyl Acyl Carrier Protein Reductase Year (2003) (22)
Inhibition of protein kinase C(alpha) by dequalinium analogues: dependence on linker length and geometry. (2000) (22)
Two-photon time-lapse microscopy of BODIPY-cholesterol reveals anomalous sterol diffusion in chinese hamster ovary cells (2012) (21)
High-density lipoprotein endocytosis in endothelial cells. (2013) (21)
Symmetrical distribution and rapid transbilayer movement of cholesterol in Mycoplasma gallisepticum membranes. (1981) (21)
Liposomes as target membranes in the study of virus receptor interaction and membrane fusion. (2003) (21)
Interaction of filipin with cholesterol in vesicles of saturated phospholipids. (1977) (21)
Total synthesis of α-1C-galactosylceramide, an immunostimulatory C-glycosphingolipid, and confirmation of the stereochemistry in the first-generation synthesis. (2011) (20)
Synthesis of photopolymerizable long-chain conjugated diacetylenic acids and alcohols from butadiyne synthons (1991) (20)
Synthesis of a photoactivatable (2S,3R)-sphingosylphosphorylcholine analogue. (2005) (20)
Inhibition of mTOR down-regulates scavenger receptor, class B, type I (SR-BI) expression, reduces endothelial cell migration and impairs nitric oxide production (2014) (20)
An improved two-step synthetic route to primary allylic alcohols from aldehydes (2010) (20)
Synthesis, characterization, mechanism of decomposition, and antiproliferative activity of a class of PEGylated benzopolysulfanes structurally similar to the natural product varacin. (2010) (20)
Mixed-chain phosphatidylcholine analogues modified in the choline moiety: preparation of isomerically pure phospholipids with bulky head groups and one acyl chain twice as long as the other. (1989) (19)
Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif (2014) (19)
Spontaneous rates of sitosterol and cholesterol exchange between phospholipid vesicles and between lysophospholipid dispersions: evidence that desorption rate is impeded by the 24.alpha.-ethyl group of sitosterol (1991) (19)
Lipid Metabolites Enhance Secretion Acting on SNARE Microdomains and Altering the Extent and Kinetics of Single Release Events in Bovine Adrenal Chromaffin Cells (2013) (19)
Synthesis of (S)-FTY720 vinylphosphonate analogues and evaluation of their potential as sphingosine kinase 1 inhibitors and activators. (2013) (19)
Permeability properties of the membrane of vesicular stomatitis virions. (1976) (19)
An efficient synthesis of D-ribo- and L-lyxo-phytosphingosine from D-tartaric acid (2005) (19)
Enantioselective Synthesis of 3-Deoxy-(R)-sphingomyelin from (S)-1-(4'-Methoxyphenyl)glycerol. (1998) (19)
Synthesis and Evaluation of the Antiproliferative Effects of 1-O-Hexadecyl-2-O- methyl-3-O-(2‘-acetamido-2‘-deoxy-β-d-glucopyranosyl)-sn-glycerol and 1-O-Hexadecyl-2-O-methyl-3-O-(2‘-amino-2‘-deoxy-β-d-glucopyranosyl)-sn-glycerol on Epithelial Cancer Cell Growth (1996) (18)
Resistance to ethanol disordering of membranes from ethanol-fed rats is conferred by all phospholipid classes. (1992) (18)
Enantioselective Syntheses of 1-O-Benzyl-sn-glycerol and 1-O-Hexadecyl-2-O-methyl-sn-glycerol via Asymmetric Dihydroxylation of Allyl 4-Methoxyphenyl Ether. Use of AD-Mix Supplemented with Potassium Persulfate (1994) (18)
Novel enantioselective synthesis of platelet activating factor and its enantiomer via ring opening of glycidyl tosylate with 1-hexadecanol (1988) (18)
A two-step synthesis of (R)- and (S)-benzylglycidyl ether (1989) (17)
Methyl group substitution at C(1), C(2) or C(3) of the glycerol backbone of a diether phosphocholine: a comparative study of bilayer chain disorder in the gel and liquid-crystalline phases. (1986) (17)
Synthesis of fluorescent lactosylceramide stereoisomers. (2006) (17)
Asymmetric synthesis of D-ribo-phytosphingosine from 1-tetradecyne and (4-methoxyphenoxy)acetaldehyde. (2010) (17)
Efficient synthesis of chiral α,β-epoxyesters via a cyclic sulfate intermediate (1998) (17)
Methanolysis of sphingomyelin. Toward an epimerization-free methodology for the preparation of D-erythro-sphingosylphosphocholine. (2000) (17)
Structure and thermotropic properties of hydrated 1-eicosyl-2-dodecyl-rac-glycero-3-phosphocholine and 1-dodecyl-2-eicosyl-rac-glycero-3-phosphocholine bilayer membranes. (1987) (17)
A concise route to d-erythro-sphingosine from N-Boc-l-serine derivatives via sulfoxide or sulfone intermediates (2002) (17)
"Pulmonary Endothelial Cell Barrier Enhancement by Novel FTY720 Analogs: Methoxy-FTY720, Fluoro-FTY720, and β-Glucuronide-FTY720". (2015) (17)
Chromatin and Disease (2007) (17)
The sphingosine kinase inhibitor 2‐(p‐hyroxyanilino)‐4‐(p‐chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress‐dependent mechanism (2013) (16)
Synthesis and use of novel ether phospholipid enantiomers to probe the molecular basis of the antitumor Effects of alkyllysophospholipids: correlation of differential activation of c-Jun NH(2)-terminal protein kinase with antiproliferative effects in neuronal tumor cells. (2004) (16)
Membrane properties of cholesterol analogs with an unbranched aliphatic side chain. (2014) (16)
FTY720 (Gilenya) Phosphate Selectivity of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P1) G Protein-coupled Receptor Requires Motifs in Intracellular Loop 1 and Transmembrane Domain 2* (2011) (16)
Synthesis of Cholesterol Analogues Bearing BODIPY Fluorophores by Suzuki or Liebeskind–Srogl Cross‐Coupling and Evaluation of Their Potential for Visualization of Cholesterol Pools (2014) (16)
BCR-ABL1 Kinase Activity but Not Its Expression Is Dispensable for Ph+ Quiescent Stem Cell Survival Which Depends on the PP2A-Controlled Jak2 Activation and Is Sensitive to FTY720 Treatment (2010) (15)
Synthesis of a novel ceramide analogue via Tebbe methylenation and evaluation of its antiproliferative activity. (2005) (15)
Glycosylated antitumor ether lipids: activity and mechanism of action. (2014) (15)
Sterol-polyene antibiotic complexation: Probe of membrane structure (1978) (15)
Enantioselective synthesis of the phosphate esters of the immunosuppressive lipid FTY720 (2006) (15)
Phospholipid interconversions in Mycoplasma capricolum. (1982) (15)
Inhibition of phospholipase C-delta 1 catalytic activity by sphingomyelin. (1996) (15)
Increased rates of lipid exchange between Mycoplasma capricolum membranes and vesicles in relation to the propensity of forming nonbilayer lipid structures. (1990) (15)
Synthesis of photoactivatable analogues of lysophosphatidic acid and covalent labeling of plasma proteins. (2006) (14)
Synthesis of phospholipids via dimethylphosphoryl chloride (1984) (14)
Reversible Acid-Induced Inactivation of the Membrane Fusion Protein of Semliki Forest Virus (2005) (14)
Phospholipids containing nitrogen- and sulfur-linked chains: kinetics of cholesterol exchange between vesicles. (1991) (14)
2'-(Trimethylammonio)ethyl 4-(hexadecyloxy)-3(S)-methoxybutanephosphonate: a novel potent antineoplastic agent. (1993) (14)
Anticancer activity of a ceramide analog containing a disulfide linkage. (2007) (14)
Synthesis of ether-linked analogues of lysophosphatidate and their effect on the proliferation of human epithelial cancer cells in vitro. (1996) (14)
Comparison of steady-state fluorescence polarization and urea permeability of phosphatidylcholine and phosphatidylsulfocholine liposomes as a function of sterol structure. (1989) (14)
An efficient asymmetric synthesis of diacylglycerols. (1994) (14)
Synthesis and antioxidant properties of an unnatural plasmalogen analogue bearing a trans O-vinyl ether linkage. (2009) (13)
Preparation of ether-linked 2-acetamido-2-deoxy β-glycolipids via zinc chloride promoted coupling of Ac4GlcNAcCl with lipid hydroxy groups (1994) (13)
The Roles of Sphingosine Kinase 1 and 2 in Regulating the Metabolome and Survival of Prostate Cancer Cells (2013) (13)
Fluorescent Sterols for the Study of Cholesterol Trafficking in Living Cells (2008) (13)
Ceramide channel: Structural basis for selective membrane targeting. (2016) (13)
Deacylation of the transmembrane domains of Sindbis virus envelope glycoproteins E1 and E2 does not affect low‐pH‐induced viral membrane fusion activity (2001) (13)
An active endocytosis pathway is required for the cytotoxic effects of glycosylated antitumor ether lipids. (2011) (13)
A New Synthetic Route to Chiral Glycerolipid Precursors Using a Cyclic Sulfate Synthon: Preparation of 1-O-Hexadecyl-3-O-(4‘-methoxyphenyl)- sn-glycerol and Its 1-Thio and 1-Aza Analogues (1998) (13)
Permeability behavior of liposomes prepared from fatty acids and fatty acid methyl esters. (1986) (12)
Photouncaging of ceramides promotes reorganization of liquid-ordered domains in supported lipid bilayers. (2013) (12)
Isosteric phosphonate analogs of ET-16-OMe. Synthesis and biological evaluation of the enantiomers of 2'-(trimethylammonio)ethyl 4-(hexadecyloxy)-3-methoxybutanephosphonate and 2'-(trimethylammonio)ethyl 4-(hexadecylthio)-3-methoxybutanephosphonate. (1994) (12)
Spin-label studies of the oligomeric structure of band 3 protein in erythrocyte membranes and in reconstituted systems. (1984) (12)
Structure and dynamics of the aliphatic cholesterol side chain in membranes as studied by (2)H NMR spectroscopy and molecular dynamics simulation. (2016) (12)
Synthesis and biochemical studies of analogs of platelet-activating factor bearing a methyl group at C2 of the glycerol backbone. (1987) (12)
Convenient synthesis of racemic mixed-chain ether glycerophosphocholines from fatty alkyl allyl ethers: useful analogs for biophysical studies. (1986) (12)
A new approach to archaebacterial lipid models (1993) (12)
Ionophorous properties of neutral diamide ligands toward calcium. (1977) (12)
Direct observation of cargo transfer from HDL particles to the plasma membrane. (2018) (11)
Constraint of the spontaneous intermembrane movement of sitosterol by its 24.alpha.-ethyl group (1990) (11)
Isolation of mycoplasma membranes by dicyclohexylcarbodiimide-induced lysis (1982) (11)
Kinetics of cholesterol and phospholipid exchange from membranes containing cross-linked proteins or cross-linked phosphatidylethanolamines. (1985) (11)
Structure of polymerizable lipid bilayers. V. Synthesis, bilayer structure and properties of diacetylenic ether and ester lipids. (1992) (11)
Preparation of chiral propargylic alcohols from α,β-unsaturated esters (2002) (11)
A photoreactive analogue of the immunosuppressant FTY720. (2006) (10)
Efficient Stereospecific Synthesis of Diamide Analogs of Phosphatidylcholine Starting from 1-(4‘-Methoxyphenyl)-sn-glycerol (1996) (10)
Organization of unesterified cholesterol in high density lipoproteins probed by filipin. (1982) (10)
Enantioselective synthesis and antiproliferative properties of an ilmofosine analog, 2'-(trimethylammonio)ethyl 3-(hexadecyloxy)-2-(methoxymethyl)propyl phosphate, on epithelial cancer cell growth. (1997) (10)
C‐Glycosphingolipids with an exo‐Methylene Substituent: Stereocontrolled Synthesis and Immunostimulation of Mouse and Human Natural Killer T Lymphocytes (2012) (10)
Transbilayer distribution of sterols in mycoplasma membranes: a review. (1983) (10)
Glycosylated antitumor ether lipids are more effective against oncogene-transformed fibroblasts than alkyllysophospholipids. (1998) (10)
BCL-2 suppresses ceramide-induced cell killing. (1996) (10)
Synthesis of novel phenoxy-linked diazirine glycero- and sphingolipid probes via trialkylaryltin intermediates (2000) (10)
Effect of double bond geometry in sphingosine base on the antioxidant function of sphingomyelin. (2009) (10)
Synthesis and Antitumor Activity of Ether Glycerophospholipids Bearing a Carbamate Moiety at the sn‐2 Position: Selective Sensitivity Against Prostate Cancer Cell Lines (2010) (10)
Synthesis and evaluation of an alpha-C-galactosylceramide analogue that induces Th1-biased responses in human natural killer T cells. (2006) (10)
Synthesis and Properties of a Photoactivatable Analogue of Psychosine (β‐Galactosylsphingosine) (2010) (10)
Synthesis and Growth Inhibitory Properties of Glycosides of 1-O- Hexadecyl-2-O-methyl-sn-glycerol, Analogues of the Antitumor Ether Lipid ET-18-OCH3 (Edelfosine). (1996) (9)
Lipid Phase Separation and Protein-Ganglioside Clustering in Supported Bilayers Are Induced by Photorelease of Ceramide. (2013) (9)
Binding properties of neutral diamide ligands for alkaline-earth cations. (1977) (9)
Kinetics of solute permeability in phospholipid vesicles. (1976) (9)
Differential basolateral–apical distribution of scavenger receptor, class B, type I in cultured cells and the liver (2014) (9)
Isolation of protein(s) containing chloride ion transport activity from thylakoid membranes. (1984) (9)
How plant inventories improve future monitoring (2012) (9)
Synthesis of cholesterol analogs having varying length alkyl side chains including cholesterol-23, 23, 24, 24, 25, 26, 26, 26, 27, 27, 27-d(11) as probes of cholesterol's functions and properties. (2013) (9)
Selective deuterium labeling of the sphingoid backbone: facile syntheses of 3,4,5-trideuterio-d-erythro-sphingosine and 3-deuterio-d-erythro-sphingomyelin. (2010) (9)
Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT 3-activated microRNAs (2019) (9)
Antitumor phospholipids: A one-pot introduction of a phosphocholine moiety into lipid hydroxy acceptors (1994) (9)
A simple synthesis of phosphonate - containing lipids. Introduction of the phosphonic acid moiety into hydrolytically-labile compounds (1975) (9)
THREE-STEP SYNTHESIS OF PLATELET-ACTIVATING FACTOR FROM CHIRAL GLYCIDOL VIA REGIOSELECTIVE MONOPHOSPHITYLATION OF 1-O-HEXADECYL-SN-GLYCEROL (1995) (8)
Cholesterol's Aliphatic Side Chain Structure Modulates Membrane Properties (2016) (8)
Synthesis and antiproliferative properties of a photoactivatable analogue of ET-18-OCH 3 (2001) (8)
Kinetics of cholesterol and phospholipid exchange between mycoplasma membranes and lipid vesicles. (1987) (8)
A convenient synthesis of D-myo-inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and L-myo-inositol 1,4,5-trisphosphate (Ins(3,5,6)P3). (1997) (8)
Microdomain structures in polymerizable and nonpolymerizable diacetylenic phosphatidylcholine monolayers (1992) (8)
Fluorescence Studies of the Binding of the Polyene Antibiotics Filipin III , Amphotericin B , . Nystatin , and Lagosin to Cholesterol ( membranes / vesicles / lecithin / probe ) (8)
Structure of polymerizable lipid bilayers VII: lateral organization of diacetylenic phosphatidylcholines with short proximal acyl chains. (1994) (8)
Analysis of reducing sugars in breakfast cereal and other foods. A general chemistry experiment. (1974) (8)
Selective Removal of Palmitic Acid from Langmuir Monolayers by Complexation with New Quaternary Ammonium β-Cyclodextrin Derivatives (2001) (7)
Mycoplasma membrane lipids. Chemical composition and transbilayer distribution. (1993) (7)
Antitumor ether lipids: An improved synthesis of ilmofosine and an enantioselective synthesis of an ilmofosine analog (1994) (7)
A facile synthesis of [14C] epicholesterol. (1990) (7)
Efficient and versatile synthesis of (2S,3R)-sphingosine and its 2-azido-3-O-benzylsphingosine analogue (2005) (7)
Pulmonary endothelial cell barrier enhancement by novel FTY720 analogs: methoxy-FTY720, fluoro-FTY720, and β-glucuronide-FTY720. (2015) (7)
PP2A Activating Drugs (PAD): Anti-Leukemic and Non-Toxic Activity of Two Novel and Non-Immunosuppressive FTY720 Derivatives (2010) (7)
Stereospecific Synthesis of Thioether Glycerophospholipids. Catalytic Asymmetric Epoxidation Followed by in situ Borohydride-Mediated Opening of Glycidol with Hexadecylmercaptan (1994) (7)
Synthesis of optically active 1-acyl-2-O-alkyl-sn-glycero-3-phosphocholine via 1-O-benzyl-sn-glycerol 3-arenesulfonate. (1990) (6)
Sterol effects and sites of sterol accumulation in Caenorhabditis elegans Published, JLR Papers in Press, November 4, 2002. DOI 10.1194/jlr.M200323-JLR200 (2003) (6)
Properties of HIV-1 associated cholesterol in addition to raft formation are important for virus infection. (2015) (6)
Synthesis and antineoplastic properties of an ether glycerophosphonocholine, and analog of ET-18-OCH3-GPC. (1992) (6)
Endothelial disruptive pro-inflammatory effects of nicotine and e-cigarette vapor exposures 1 (2015) (6)
The alpha-anomers and Beta-anomers of 1-o-hexadecyl-2-o-methyl-3-s-thioglucosyl-sn-glycerol inhibit the proliferation of epithelial cancer cell-lines. (1994) (6)
The effect of cholesterol on glycerophosphono- and glycerophosphinocholines. Permeability measurements in lipid vesicles. (1986) (6)
Synthesis of fluorescent phosphatidylinositols using a novel inositol H-phosphonate (1998) (6)
ET-18-OCH3 inhibits the phosphorylation and activation of p70 S6 kinase in MCF-7 cells. (2005) (6)
A short synthesis of antitumor ether thioglycolipids: Thioglycosidation of a glucose donor with a tributylstannyl sulfide acceptor (1995) (6)
FTY720 Restores PP2A Tumor Suppressor Activity in Polycythemia Vera CD34+ Progenitors Through Inhibition of Jak2 V617F- and PI-3Kγ-Dependent SET Serine Phosphorylation and Enhancement of NOS-Dependent PP2A Tyrosine Nitration (2011) (6)
Synthesis of phosphatidylcholine analogs with an alkyl group at C1 or C3 of the glycerol moiety. (1985) (5)
A One-Pot Synthesis of Dimethyl 2,3-O-Benzylidene-L-tartrate from L-Tartaric Acid (1993) (5)
An Improved Two-Step Synthetic Route to Primary Allylic Alcohols from Aldehydes. (2010) (5)
Synthesis and antiproliferative properties of a new ceramide analog of varacin. (2016) (5)
Synthetic Analogues of FTY720 Regulate Pulmonary Vascular PermeabilityIn VivoandIn Vitro. (2009) (5)
Synthesis of Photopolymerizable Long-Chain Conjugated Diacetylenic Acids and Alcohols from Butadiyne Synthons. (2010) (4)
Interaction of cholesterol with conformationally restricted phospholipids in vesicles. (1992) (4)
Synthesis of new trans double-bond sphingolipid analogues: Delta(4,6) and Delta(6) ceramides. (2002) (4)
Chemical Preparation of Sphingosine and Sphingolipids: A Review of Enantioselective Synthesis (1994) (4)
Synthesis and photochemical properties of PEGylated coumarin-caged ceramides for cell studies. (2016) (4)
Abstract LB-109: BCR-ABL1 kinase activity but not its expression is dispensable for Ph+ quiescent stem cell survival which depends on the PP2A-controlled Jak2 activation and is sensitive to FTY720 treatment (2011) (4)
Stereoselective Total Synthesis of Serine Palmitoyl‐CoA Transferase Inhibitors (2006) (4)
Phospholipid–Cholesterol Bilayers (2007) (4)
An Efficient Stereocontrolled Route to Both Enantiomers of Platelet Activating Factor and Analogues with Long‐Chain Esters at C2: Saturated and Unsaturated Ether Glycerolipids by Opening of Glycidyl Arenesulfonates. (1990) (4)
Synthesis and antitumor properties of a plasmalogen methyl ether analogue (2001) (4)
Equilibrium and kinetic measurements of actinomycin binding to deoxyribonucleic acid in the presence of competing drugs. (1975) (4)
Two different sites of action for platelet activating factor and 1-O-alkyl-2-O-methyl-sn-glycero-3-phosphocholine on platelets and leukemic cells. (1992) (4)
Effect of ether glycerol lipids on interleukin-1β release and experimental autoimmune encephalomyelitis. (2016) (4)
Stereospecific and regiospecific ring opening of glycidol with primary and secondary alcohols mediated by diisobutylaluminium hydride (1995) (4)
Pharmacologic Restoration of PP2A Activity and Interference with the SET-PP2A Interplay by FTY720 and Its Non-Immunosuppressive Derivative as a Novel and Efficient Therapy for Ph-Negative Myeloproliferative Disorders (2010) (3)
Synthesis and biological activity of alkynoic acids derivatives against mycobacteria. (2016) (3)
A comparison of the lytic properties of two ether-linked lipids, one with and one without antineoplastic activity. (1994) (3)
Sphingosine-1-phosphate receptor-independent lung endothelial cell barrier disruption induced by FTY720 regioisomers (2020) (3)
Synthesis of Half-Deuterated Palmitic and Palmitoleic Acids from THF-d8 (1996) (3)
Practical multigram-scale synthesis of 4,6- and 4,8-sphingadienes, chemopreventive sphingoid bases. (2012) (3)
Diacetylenic sterols: New potentially photopolymerizable lipids (1995) (3)
Effects of a water-soluble antitumor ether phosphonoinositide, D-myo-inositol 4-(hexadecyloxy)-3(S)-methoxybutanephosphonate (C4-PI), on inositol lipid metabolism in breast epithelial cancer cell lines. (1999) (3)
Sphingosine-1-phosphate receptor-independent lung endothelial cell barrier disruption induced by FTY720 regioisomers (2020) (3)
Synthesis and bioactivity of α-galactosylceramide analogues bearing an aryl group within the fatty amide chain (2013) (3)
Synthesis of Sphingomyelin and Ceramide 1-Phosphate from Ceramide Without Protection of the Allylic Hydroxyl Group. (1995) (3)
Synthetic Sphingolipids as Bioactive Molecules (2008) (3)
Bax, Bcl-xl Exert their Regulation on Different Sites on the Ceramide Channel (2011) (3)
The assembly of glycosphingolipid determines their immunomodulatory effect: A novel method for structure-based design of immunotherapy. (2020) (3)
Stereoselective total synthesis of serine palmitoyl-CoA transferase inhibitors (2006) (3)
Enantioselective Synthesis and Antiproliferative Properties of an Ilmofosine Analogue, 2′-(Trimethylammonio)ethyl 3-(Hexadecyloxy)-2-( methoxymethyl)propyl Phosphate, on Epithelial Cancer Cell Growth. (1997) (2)
TLC ELL-12: Oncolytic (2001) (2)
Effects of Cross‐linking of Membrane Components on Cholesterol and Phospholipid Translocation a (1984) (2)
2′‐(Trimethylammonio)ethyl 4‐(Hexadecyloxy)‐3(S)‐ methoxybutanephosphonate (I): A Novel Potent Antineoplastic Agent. (1994) (2)
Therapeutic Potential Of FTY720-Analogs In Cigarette-Smoke Induced Lung Injury That Is Dependent Upon Sphingosine-1 Phosphate Receptor-1, S1PR1 (2012) (2)
Enantioselective Syntheses of 1‐O‐Benzyl‐sn‐glycerol and 1‐O‐Hexadecyl‐ 2‐O‐methyl‐sn‐glycerol via Asymmetric Dihydroxylation of Allyl 4‐ Methoxyphenyl Ether. Use of AD‐Mix Supplemented with Potassium Persulfate. (1994) (2)
FTY720 S‐ene‐phosphonate is a novel pan‐antagonist of the S1P receptors that inhibits lymphocyte egress (2010) (2)
Efficient Stereospecific Synthesis of Diamide Analogues (VII) of Phosphatidylcholine Starting from 1-(4′-Methoxyphenyl)-sn-glycerol. (1997) (2)
Erratum to “In-situ investigation of partially deuterated fatty acid and phospholipid monolayers at the air-water interface by IR reflection-absorption spectroscopy” [thinsolid films284–285 (1996) 428–431] (1997) (2)
Stereoselective Preparation of Ceramide and Its Skeleton Backbone Modified Analogues via Cyclic Thionocarbonate Intermediates Derived by Catalytic Asymmetric Dihydroxylation of α,β‐Unsaturated Ester Precursors. (2001) (2)
A fluorescent alkyllysophospholipid analog exhibits selective cytotoxicity against the hormone-insensitive prostate cancer cell line PC3. (2014) (2)
Synthesis and Antiproliferative Properties of a Photoactivatable Analogue of ET‐18‐OCH3. (2002) (2)
1-O-hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine inhibits diacylglycerol kinase in WEHI-3B cells. (1993) (2)
Isosteric Phosphonate Analogues of ET‐16‐OMe. Synthesis and Biological Evaluation of the Enantiomers of 2′‐(Trimethylammonio)ethyl 4‐( Hexadecyloxy)‐3‐methoxybutanephosphonate and 2′‐(Trimethylammonio) ethyl 4‐(Hexadecylthio)‐3‐methoxybutanephosphonate. (1994) (2)
Microdomains in Polymerizable Diacetylenic Phosphatidylcholine Monolayers (1992) (2)
In-situ investigation of partially deuterated fatty acid and phospholipid monolayers at the air-water interface by IR reflection-absorption spectroscopy (1996) (2)
Critical Role Of Sphingolipid Pathway Components In Murine Radiation-Induced Lung Injury: Protection By Sphingosine 1 Phosphate Analogues (2011) (2)
Three-Step Synthesis of Platelet-Activating Factor from Chiral Glycidol via Regioselective Monophosphitylation of 1-O-Hexadecyl-sn- glycerol. (1996) (1)
Regiospecific Opening of Glycidyl Derivatives Mediated by Boron Trifluoride. Asymmetric Synthesis of Ether-Linked Phospholipids. (1990) (1)
DHA Disorders Raft-Like Domains as Revealed by Solid State 2H NMR (2015) (1)
Synthesis and Evaluation of an α-C-Galactosylceramide Analogue that Induces Th1-Biased Responses in Human Natural Killer T Cells. (2007) (1)
The Effect of Sterol Side Chain Conformation on Lateral Lipid Domain Formation in Monolayer Membranes (1996) (1)
Corrigendum to “The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner” [Cell. Signal. 23(7) (2011) 1144-1152]☆ (2012) (1)
DHA Alters Raft-like Membrane Domains as Revealed by Solid State 2H NMR Spectroscopy (2015) (1)
FTY720 Analogs Improve Alveolar Macrophages Efferocytosis During Cigarette Smoking (2012) (1)
Retraction: Visualization of Lipid Metabolism in the Zebrafish Intestine Reveals a Relationship between NPC1L1-Mediated Cholesterol Uptake and Dietary Fatty Acid. (2015) (1)
Corrigendum to “(R)-FTY720 methyl ether is a specific sphingosine kinase 2 inhibitor: Effect on sphingosine kinase 2 expression in HEK 293 cells and actin rearrangement and survival of MCF-7 breast cancer cells” [Cell. Signal. 23 (2011) 1590–1595] (2012) (1)
Pharmacological sphingosine-1 phosphate receptor 1 targeting in cigarette smoke-induced emphysema in mice. (2022) (1)
A Facile Stereoselective Synthesis of Ether-Linked β-D-Maltosyl- and β-D-Lactosyl-glycerolipids via Peracetylated Disaccharide α-Phosphoramidates (1994) (1)
1 FTY 720 ANALOGUES AS SPHINGOSINE KINASE 1 INHIBITORS : ENZYME INHIBITION KINETICS , ALLOSTERISM , PROTEASOMAL DEGRADATION AND ACTIN REARRANGEMENT IN MCF-7 BREAST CANCER CELLS (2011) (1)
A Novel Water-Soluble Phosphonate Analog of Phosphatidylinositol, D-Myo-Inositol4-(Hexadecyloxy)-3(5)-Methoxybutanephosphonate (C4-PI), Inhibits Epithelial Cell Proliferation and is a Substrate but not an Inhibitor of Phosphatidylinositol 3-Kinase (1998) (1)
Synthesis and evaluation of the antiproliferative effects of 1-O-hexadecyl-2-O-methyl-3-O-(2'-acetamido-2'-deoxy-beta-D- glucopyranosyl)-sn-glycerol and 1-O-hexadecyl-2-O-methyl-3-0- (2'-amino-2'-deoxy-beta-D-glucopyranosyl)-sn-glycerol on epithelial cancer cell growth. (1996) (1)
Preparation of Ether-Linked 2-Acetamido-2-deoxy β-Glycolipids via Zinc Chloride Promoted Coupling of Ac4GlcNAc-Cl with Lipid Hydroxy Groups. (1994) (1)
FTY720 S-phosphonate Exhibits Superior Barrier Promoting Properties To S1P And FTY720 In Vitro And In Vivo (2011) (1)
Sphingolipid Involvement In The Cigarette-smoke-induced Endothelial Barrier Dysfunction (2010) (1)
Conversion of methylallyl alcohol into C2-methyl-1,2-di-O-hexadecylglycerophosphocholine, a conformationally restricted phospholipid. (1989) (1)
Solid-state 2H NMR Reveals the Impact of DHA on Molecular Organization in Raft-Like Domains (2016) (1)
DHA and EPA Interaction with Raft Domains Observed With Solid-State 2H NMR Spectroscopy (2013) (0)
Regioselective and Stereospecific Azidation of 1,2‐ and 1,3‐Diols by Azidotrimethylsilane via a Mitsunobu Reaction. (2000) (0)
Synthesis of Novel Phenoxy‐Linked Diazirine Glycero‐ and Sphingolipid Probes via Trialkylaryltin Intermediates. (2000) (0)
Stereospecific and Regiospecific Ring Opening of Glycidol with Primary and Secondary Alcohols Mediated by Diisobutylaluminum Hydride. (1996) (0)
A New Approach to Archaebacterial Lipid Models. (1993) (0)
FTY720‐PHOSPHATE (GILENYA) SELECTIVITY OF S1P1 GPCR REQUIRES MOTIFS IN INTRACELLULAR LOOP 1 AND TRANSMEMBRANE DOMAIN 2 (2012) (0)
A One-Pot Synthesis of Dimethyl 2,3-O-Benzylidene-L-tartrate (IV) from L-Tartaric Acid. (1994) (0)
Combinations of cholesterol removing chemicals and cholesterol analogues as a potential microbicides (2005) (0)
Differential basolateral–apical distribution of scavenger receptor, class B, type I in cultured cells and the liver (2014) (0)
Raft Busters: A Molecular Role for DHA in Biological Membranes? (2016) (0)
Partitioning and Single-Molecule Diffusion Dynamics of Bodipy-FTY720 in Biomembranes (2011) (0)
Multimodal Imaging and Spectroscopy Approaches for Studying Ceramide-induced Reorganization of Lipid Membranes (2013) (0)
CRYSTAL STRUCTURE ANALYSIS OF PLASMODIUM FALCIPARUM ENOYL-ACYL-CARRIER-PROTEIN REDUCTASE WITH NADH (2003) (0)
A Short Synthesis of Antitumor Ether Thioglycolipids: Thioglycosidation of a Glucose Donor with a Tributylstannyl Sulfide Acceptor. (1995) (0)
Disordering of Raft Domains by DHA and EPA observed with Solid-State Deuterium NMR Spectroscopy (2013) (0)
Dissecting the contribution of cholesterol in viral entry: a potential role in fusion pore formation (2005) (0)
Stereospecific Synthesis of Thioether Glycerophospholipids. Catalytic Asymmetric Epoxidation Followed by in situ Borohydride-Mediated Opening of Glycidol with Hexadecylmercaptan. (1994) (0)
EFFICIENT SYNTHESIS OF CHIRAL ALPHA , BETA -EPOXYESTERS VIA A CYCLIC SULFATE INTERMEDIATE (1998) (0)
A Two-Step Synthesis of (R)- and (S)-Benzyl Glycidyl Ether. (1990) (0)
Synthetic analogues of FTY 720 differentially regulate pulmonary vascular permeability in vivo and in vitro (2009) (0)
This information is current as-Galactosylceramide C-α NKT TCR Recognition of CD 1 d-Godfrey and (2011) (0)
Antitumor Phospholipids: A One-Pot Introduction of a Phosphocholine Moiety into Lipid Hydroxy Acceptors. (1994) (0)
Diacetylenic Sterols: New Potentially Photopolymerizable Lipids. (1996) (0)
Differential Recognition of LPA and Rosiglitazone by PPARγ 1 (2006) (0)
Efficient Synthesis of Chiral α,β-Epoxyesters via a Cyclic Sulfate Intermediate. (1998) (0)
Determining the mechanistic role of cholesterol in HIV-1 infectivity (2005) (0)
Structural Basis of FTY720 (Gilenya) Phosphate Selectivity of the Sphingosine 1‐Phosphate Receptor Subtype 1 (2013) (0)
THE BINDING OF NICOTINAMIDE-ADENINE DINUCLEOTIDE TO YEAST D-GLYCERALDEHYDE-3-PHOSPHA TE DEHYDROGENASE: TEMPERATURE-JUMP (0)
A facile synthesis of [ ' * C ] epicholesterol (2002) (0)
Differential Effects Of Ceramide Metabolites On Microvascular Endothelial Barrier Function (2011) (0)
55 NOVEL ANALOGS OF FTY720 PROMOTE PULMONARY VASCULAR BARRIER FUNCTION. (2006) (0)
Facile Diacylation of Glycidyl Tosylate. Chiral Synthesis of Symmetric-Chain Glycerophospholipids. (1989) (0)
An efficient asymmetric synthesis of diacylgl ycerols (1994) (0)
Differential scanning calorimetry study of the influence of phospholipid analogs with a carbonyl-terminated sn-2 chain on the interdigitated phases formed by 1-stearoyl-2-capryl-sn-glycero-3-phosphatidylcholine (C18:C10-PC). (1996) (0)
Tris(trimethylsilyl) Phosphite (2001) (0)
Rates of Lipid Movement between Mycoplasma Cells and Vesicles and between Small Unilamellar Vesicles Are Decreased by Sphingomyelin Incorporation a (1986) (0)
Abstract 17: Reverse Cholesterol Transport Relies on a Functional Lymphatic Network (2012) (0)
The roles of sphingosine kinase 1 and 2 in regulating the Warburg effect in prostate cancer cells (2013) (0)
Exploring the Formation, Lifetime and Dissociation Statistics of Acid-Amine Bonds (0)
Abstract 56: Macrophage Reverse Cholesterol Transport in Mice Relies on The Lymphatic Vasculature (2013) (0)
tuberculosis Mycobacterium Crystal Structure of the ENZYMOLOGY (2014) (0)
FTY720 S-Phosphonate Enhances Endothelial Barrier Function Via Cytoskeletal Rearrangement And Protects Against Bleomycin-Induced Acute Lung Injury In Mice (2012) (0)
M.TB. ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH NAD+ AND C16-FATTY-ACYL-SUBSTRATE (1999) (0)
Probing the Structural and Signalling Roles of Ceramide using 6-Bromo-7-Hydroxycoumarin Caged Derivatives (2012) (0)
Selective inhibitors and allosteric activators of sphingosine kinase : PCT/GB2014/050264 (2014) (0)
Synthesis of actinomycin and analogs. 12. Synthesis and some properties and antitumor effects of the actinomycin lactam analog, [di-(1'-L-.alpha.,.beta.-diaminopropionic acid)]actinomycin D (1976) (0)
Fusion of Semliki Forest Virus in the Absence of Sphingolipids Implications for the Role of Sphingolipids in Alphavirus Membrane Fusion (2018) (0)
Byun, Hoe-Sup and Pyne, Susan and Macritchie, Neil and Pyne, Nigel J and Bittman, Robert (2013) Novel sphingosine-containing analogues selectively inhibit sphingosine kinase (SK) isozymes, induce SK1 proteasomal degradation and reduce DNA synthesis in human (2017) (0)
Preparation of Chiral Propargylic Alcohols from α,β-Unsaturated Esters. (2003) (0)
HDL particles incorporate into lipid bilayers – a combined AFM and single molecule fluorescence microscopy study (2017) (0)
HDL-Lipid Uptake is Regulated by Elastic Properties of the Plasma Membrane (2014) (0)
A SIMPLE SYNTHESIS OF PHOSPHONATE - CONTAINING LIPIDS, INTRODUCTION OF THE PHOSPHONIC ACID MOIETY INTO HYDROLYTICALLY-LABILE COMPOUNDS (1975) (0)
HIV functions as lipid rafts during viral entry (2007) (0)
Utilization of Caged Ceramide and Ceramide 1-Phosphate Analogs for Monitoring Cellular Events after Photoactivation (2015) (0)
ET-18-OCH 3 Inhibits the Phosphorylation and Activation of p 70 S 6 Kinase in MCF-7 Cells (2009) (0)
A new α‐C‐galactosylceramide analog: promotion of Th1‐biased responses in human CD1d‐reactive Vα24‐invariant natural killer T cells (2007) (0)
A New Synthetic Route to Chiral Glycerolipid Precursors Using a Cyclic Sulfate Synthon: Preparation of 1‐O‐Hexadecyl‐3‐O‐(4′‐methoxyphenyl)‐sn‐glycerol and Its 1‐Thio and 1‐Aza Analogues. (1999) (0)
Chemical Synthesis of Glycerophospholipids and Their Analogues (2010) (0)
Cholesterol-regulated signaling and transport in endo-lysosomes (2011) (0)
Solid State 2H NMR Studies of the Disordering of Raft-Like Domains by n-3 PUFA (2014) (0)
Glycidyl Derivatives as Chiral C3 Synthons. Ring Opening Catalyzed by BF3 Etherate. (1989) (0)
Field study to obtain trace element mass balances at Kingston Steam Plant. Final report Mar 77-Jun 81 (1982) (0)
Reversible Conformational Changes of Semliki Forest Virus E1 (2004) (0)
Crystal Structure Analysis of Plasmodium falciparum enoyl-acyl-carrier-protein reductase with Triclosan Analog (2003) (0)
dicyclohexylcarbodiimide-in membranes by Isolation of mycoplasma (2013) (0)
Enantioselective Synthesis of 3-Deoxy-(R)-sphingomyelin from (S)-1-(4′-Methoxyphenyl)glycerol. (1998) (0)
Interaction of Cholesterol with Glycerophosphono‐and Glycerophosphinocholines a (1987) (0)
The Novel S-phosphonate Analog Of FTY720 Regulates Pulmonary Vascular Permeability (2010) (0)
Determining the mechanistic role of cholesterol in HIV-1 entry (2006) (0)

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