Robert C. Green
#46,217
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American geneticist
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Why Is Robert C. Green Influential?
(Suggest an Edit or Addition)According to Wikipedia, Robert C. Green is an American medical geneticist, physician, and public health researcher. He directs the Genomes2People Research Program in translational genomics and health outcomes in the Division of Genetics at Brigham and Women's Hospital and the Broad Institute, and is Director of the Preventive Genomics Clinic at Brigham and Women's Hospital. Research led by Green includes clinical and research aspects of genomic and precision medicine, including the development and disclosure of Alzheimer's disease risk estimates and one of the first prospective studies of direct-to-consumer genetic testing services . He has studied the implementation of medical sequencing in healthy adults , newborns , and active duty military personnel . As of 2020, he is leading the first research collaboration to explore return of genomic results and better understand penetrance in a population-based cohort of underrepresented minorities. He has led the Preventive Genomics Clinic at Brigham and Women's Hospital since its creation in 2019.
Robert C. Green's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease (2013) (3484)
- The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods (2008) (2996)
- ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing (2013) (2235)
- Common variants in MS4A4/MS4A6E, CD2uAP, CD33, and EPHA1 are associated with late-onset Alzheimer’s disease (2011) (1656)
- The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease (2007) (1112)
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (1073)
- Common genetic variants influence human subcortical brain structures (2015) (731)
- Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis (2016) (716)
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease (2017) (693)
- Diagnostic clinical genome and exome sequencing. (2014) (567)
- Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial. (2009) (567)
- The Alzheimer’s Disease Neuroimaging Initiative: A review of papers published since its inception (2012) (553)
- Depression as a risk factor for Alzheimer disease: the MIRAGE Study. (2003) (524)
- The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception (2012) (513)
- The Alzheimer's Disease Neuroimaging Initiative: Progress report and future plans (2010) (473)
- Managing incidental findings and research results in genomic research involving biobanks and archived data sets (2012) (419)
- Clinical core of the Alzheimer's disease neuroimaging initiative: Progress and plans (2010) (395)
- Disclosure of APOE genotype for risk of Alzheimer's disease. (2009) (376)
- Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib. (2008) (372)
- Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans (2010) (360)
- Risk of dementia among white and African American relatives of patients with Alzheimer disease. (2002) (359)
- The genetic architecture of the human cerebral cortex (2018) (355)
- Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. (2013) (345)
- Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial (2007) (321)
- Trail Making Test errors in normal aging, mild cognitive impairment, and dementia. (2008) (318)
- Extended results of the Alzheimer’s disease anti-inflammatory prevention trial (2011) (317)
- Vascular factors predict rate of progression in Alzheimer disease (2007) (315)
- Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis (2012) (308)
- 2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception (2015) (287)
- Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study. (2006) (285)
- Performance of ACMG-AMP Variant-Interpretation Guidelines among Nine Laboratories in the Clinical Sequencing Exploratory Research Consortium. (2016) (283)
- Performance of ACMG-AMP Variant-Interpretation Guidelines among Nine Laboratories in the Clinical Sequencing Exploratory Research Consortium. (2016) (244)
- Novel genetic loci associated with hippocampal volume (2017) (238)
- Postmenopausal hormone therapy and Alzheimer’s disease risk: interaction with age (2004) (236)
- Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative (2018) (225)
- Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans (2015) (219)
- A comprehensive genetic association study of Alzheimer disease in African Americans. (2011) (218)
- Health Behavior Changes After Genetic Risk Assessment for Alzheimer Disease: The REVEAL Study (2008) (217)
- Hippocampal sclerosis in advanced age: clinical and pathological features. (2011) (214)
- Relationship between Serum and Brain Carotenoids, α-Tocopherol, and Retinol Concentrations and Cognitive Performance in the Oldest Old from the Georgia Centenarian Study (2013) (214)
- Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials (2017) (214)
- Progression of cognitive, functional, and neuropsychiatric symptom domains in a population cohort with Alzheimer dementia: the Cache County Dementia Progression study. (2011) (212)
- The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement (2017) (206)
- Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology (2016) (201)
- Four distinct trajectories of tau deposition identified in Alzheimer’s disease (2021) (200)
- The Scientific Foundation for Personal Genomics: Recommendations from a National Institutes of Health–Centers for Disease Control and Prevention Multidisciplinary Workshop (2009) (196)
- Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study (2019) (194)
- Novel genetic loci underlying human intracranial volume identified through genome-wide association (2016) (192)
- APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study (2013) (184)
- Impact of the Alzheimer's Disease Neuroimaging Initiative, 2004 to 2014 (2015) (175)
- Newborn Sequencing in Genomic Medicine and Public Health (2017) (163)
- Exploring concordance and discordance for return of incidental findings from clinical sequencing (2012) (163)
- Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE (2015) (161)
- Estimating risk curves for first-degree relatives of patients with Alzheimer’s disease: The REVEAL study (2004) (161)
- Conversion to dementia from mild cognitive disorder (2006) (160)
- Ethics and Genomic Incidental Findings (2013) (156)
- Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers (2013) (153)
- Epidemiology of apathy in older adults: the Cache County Study. (2007) (152)
- Genetic architecture of subcortical brain structures in 38,851 individuals (2019) (148)
- Differences Between African Americans and Whites in Their Perceptions of Alzheimer Disease (2003) (147)
- APOE, vascular pathology, and the AD brain (2005) (146)
- The adult galactosemic phenotype (2012) (143)
- Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity (2013) (143)
- Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine. (2016) (143)
- The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine (2014) (142)
- Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. (2014) (140)
- Genetic testing for Alzheimer's disease and its impact on insurance purchasing behavior. (2005) (139)
- Distinct High-Profile Methylated Genes in Colorectal Cancer (2009) (138)
- Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk Estimates: Effect on Low-Density Lipoprotein Cholesterol Levels (the MI-GENES Clinical Trial). (2016) (138)
- Genome-wide association study of the rate of cognitive decline in Alzheimer's disease (2014) (138)
- The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI) (2013) (137)
- Predicting Alzheimer’s disease progression using multi-modal deep learning approach (2019) (136)
- Genetic Risk Assessment for Adult Children of People With Alzheimer’s Disease: The Risk Evaluation and Education for Alzheimer’s Disease (REVEAL) Study (2005) (136)
- Communicating genetic risk information for common disorders in the era of genomic medicine. (2013) (134)
- Personalized Genetic Risk Counseling to Motivate Diabetes Prevention (2012) (131)
- Interpretation of Genomic Sequencing Results in Healthy and Ill Newborns: Results from the BabySeq Project. (2019) (128)
- GINA, genetic discrimination, and genomic medicine. (2015) (126)
- The Atlanta FICSIT Study: Two Exercise Interventions to Reduce Frailty in Elders (1993) (126)
- Caregiver-recipient closeness and symptom progression in Alzheimer disease. The Cache County Dementia Progression Study. (2009) (123)
- Lower-extremity function in cognitively healthy aging, mild cognitive impairment, and Alzheimer's disease. (2010) (116)
- Variable awareness of deficits in Alzheimer's disease (1993) (116)
- Who seeks genetic susceptibility testing for Alzheimer’s disease? Findings from a multisite, randomized clinical trial (2004) (112)
- The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ɛ3/ɛ3 genotype (2011) (110)
- The Impact of Whole-Genome Sequencing on the Primary Care and Outcomes of Healthy Adult Patients: A Pilot Randomized Trial. (2017) (110)
- Direct-to-Consumer Genetic Testing: User Motivations, Decision Making, and Perceived Utility of Results (2017) (110)
- Are physicians prepared for whole genome sequencing? a qualitative analysis (2016) (109)
- Compensatory recruitment of neural resources during overt rehearsal of word lists in Alzheimer's disease. (1998) (108)
- GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP. (2015) (108)
- Apolipoprotein E genotype in patients with alzheimer's disease: Implications for the risk of dementia among relatives (1995) (107)
- Secondary findings from clinical genomic sequencing: prevalence, patient perspectives, family history assessment, and health-care costs from a multisite study (2018) (107)
- Development of a process to disclose amyloid imaging results to cognitively normal older adult research participants (2014) (105)
- Hexanucleotide repeat expansions in C9ORF72 in the spectrum of motor neuron diseases (2012) (104)
- Association between apolipoprotein E genotype and Alzheimer disease in African American subjects. (2002) (103)
- Population-based study of medical comorbidity in early dementia and "cognitive impairment, no dementia (CIND)": association with functional and cognitive impairment: The Cache County Study. (2005) (99)
- Processes and preliminary outputs for identification of actionable genes as incidental findings in genomic sequence data in the Clinical Sequencing Exploratory Research Consortium (2013) (99)
- Polymorphisms in the PON gene cluster are associated with Alzheimer disease. (2006) (99)
- The BabySeq project: implementing genomic sequencing in newborns (2018) (98)
- Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease (2020) (96)
- Methodological Considerations in Studying Centenarians: Lessons Learned From the Georgia Centenarian Studies (2007) (96)
- Assessing the Costs and Cost-Effectiveness of Genomic Sequencing (2015) (95)
- A systematic approach to the reporting of medically relevant findings from whole genome sequencing (2014) (91)
- Disclosing pathogenic genetic variants to research participants: quantifying an emerging ethical responsibility. (2012) (90)
- Reasons for Seeking Genetic Susceptibility Testing Among First‐Degree Relatives of People With Alzheimer Disease (2003) (89)
- Anosognosia in Alzheimer's disease. (1996) (87)
- Returning a Research Participant's Genomic Results to Relatives: Analysis and Recommendations (2015) (84)
- Consumer Perceptions of Interactions With Primary Care Providers After Direct-to-Consumer Personal Genomic Testing. (2016) (83)
- A Taxonomy of Medical Uncertainties in Clinical Genome Sequencing (2017) (80)
- Consumers report lower confidence in their genetics knowledge following direct-to-consumer personal genomic testing (2015) (79)
- Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease (2016) (78)
- Brain pathologies in extreme old age (2016) (78)
- Comprehensive red blood cell and platelet antigen prediction from whole genome sequencing: proof of principle (2015) (78)
- Erratum: Performance of ACMG-AMP Variant-Interpretation Guidelines among Nine Laboratories in the Clinical Sequencing Exploratory Research Consortium (American Journal of Human Genetics (2016) 98(6) (1067–1076) (S0002929716300593) (10.1016/j.ajhg.2016.03.024)) (2016) (77)
- Development and validation of a computational method for assessment of missense variants in hypertrophic cardiomyopathy. (2011) (77)
- Vascular factors and risk for neuropsychiatric symptoms in Alzheimer's disease: the Cache County Study (2008) (76)
- Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment (2013) (76)
- Clock drawing performance in cognitively normal elderly. (2008) (75)
- Reporting genomic sequencing results to ordering clinicians: incidental, but not exceptional. (2013) (74)
- Regulation: The FDA is overcautious on consumer genomics (2014) (74)
- Non-coding variability at the APOE locus contributes to the Alzheimer’s risk (2019) (74)
- ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology (2014) (72)
- How Well Do Customers of Direct-to-Consumer Personal Genomic Testing Services Comprehend Genetic Test Results? Findings from the Impact of Personal Genomics Study (2015) (71)
- Nonsteroidal anti-inflammatory drug use and Alzheimer's disease risk: the MIRAGE Study (2005) (71)
- Effect of Alzheimer disease genetic risk disclosure on dietary supplement use. (2010) (71)
- “I know what you told me, but this is what I think:” Perceived risk of Alzheimer disease among individuals who accurately recall their genetics-based risk estimate (2010) (71)
- Direct to consumer genetic testing: Avoiding a culture war (2009) (70)
- Robust Identification of Alzheimer’s Disease subtypes based on cortical atrophy patterns (2017) (69)
- A curated gene list for reporting results of newborn genomic sequencing (2017) (66)
- Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease. (2008) (66)
- Unawareness of cognitive impairments in Alzheimer's disease (1994) (64)
- Variations in predicted risks in personal genome testing for common complex diseases (2013) (64)
- GA4GH: International policies and standards for data sharing across genomic research and healthcare (2021) (62)
- Willingness to pay for genetic testing for Alzheimer's disease: a measure of personal utility. (2011) (62)
- A Comparison of Whole Genome Sequencing to Multigene Panel Testing in Hypertrophic Cardiomyopathy Patients (2017) (62)
- Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection (2021) (61)
- Disclosure of Personalized Rheumatoid Arthritis Risk Using Genetics, Biomarkers, and Lifestyle Factors to Motivate Health Behavior Improvements: A Randomized Controlled Trial (2018) (60)
- Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans (2012) (59)
- Genetic testing for Alzheimer's and long-term care insurance. (2010) (58)
- Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer’s disease (2017) (58)
- Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network. (2019) (58)
- Toward clinical genomics in everyday medicine: perspectives and recommendations (2016) (57)
- Aggregate penetrance of genomic variants for actionable disorders in European and African Americans (2016) (56)
- Genetic susceptibility testing for Alzheimer disease: motivation to obtain information and control as precursors to coping with increased risk. (2006) (56)
- Understanding dementia prevalence among centenarians. (2012) (56)
- Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology (2020) (56)
- Protective variant for hippocampal atrophy identified by whole exome sequencing (2015) (56)
- Clinical Genome Sequencing (2013) (56)
- Shared genetic contribution to ischemic stroke and Alzheimer's disease (2016) (55)
- Effects of traumatic brain injury and posttraumatic stress disorder on Alzheimer’s disease in veterans, using the Alzheimer’s Disease Neuroimaging Initiative (2014) (55)
- Automated typing of red blood cell and platelet antigens: a whole-genome sequencing study. (2018) (54)
- Health-care referrals from direct-to-consumer genetic testing. (2010) (53)
- Statin use and the risk of Alzheimer’s disease: The MIRAGE Study (2006) (53)
- Genetic susceptibility testing versus family history–based risk assessment: Impact on perceived risk of Alzheimer disease (2005) (53)
- The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory (2019) (52)
- Slowly progressive apraxia in Alzheimer's disease. (1995) (52)
- Validity of the Mattis Dementia Rating Scale for detection of cognitive impairment in the elderly. (1995) (52)
- The Framingham Brain Donation Program: neuropathology along the cognitive continuum. (2012) (52)
- Genomic sequencing in clinical practice: applications, challenges, and opportunities (2016) (52)
- Polygenic risk scores in the clinic: new perspectives needed on familiar ethical issues (2021) (51)
- How to know when physicians are ready for genomic medicine (2015) (51)
- Guidelines for return of research results from pediatric genomic studies: deliberations of the Boston Children’s Hospital Gene Partnership Informed Cohort Oversight Board (2014) (51)
- Predictive Genetic Testing for Alzheimer's Disease: Impact upon Risk Perception (2005) (51)
- Patient understanding of, satisfaction with, and perceived utility of whole genome sequencing: Findings from the MedSeq Project (2017) (51)
- Effects of general medical health on Alzheimer's progression: the Cache County Dementia Progression Study (2012) (50)
- The beliefs, motivations, and expectations of parents who have enrolled their children in a genetic biorepository (2012) (50)
- The role of disease perceptions and results sharing in psychological adaptation after genetic susceptibility testing: the REVEAL Study (2010) (49)
- Clock drawing test ratings by dementia specialists: interrater reliability and diagnostic accuracy. (2010) (49)
- Prenatal DNA Sequencing: Clinical, Counseling, and Diagnostic Laboratory Considerations (2018) (48)
- Characterizing genetic variants for clinical action (2014) (48)
- Psychological outcomes related to exome and genome sequencing result disclosure: a meta-analysis of seven Clinical Sequencing Exploratory Research (CSER) Consortium studies (2019) (48)
- Personal Genome Sequencing in Ostensibly Healthy Individuals and the PeopleSeq Consortium (2016) (48)
- Comparison of Alzheimer’s disease risk factors in white and African American families (2003) (47)
- Pupillary response to tropicamide in patients with Alzheimer disease. (1996) (47)
- Parental Interest in Genomic Sequencing of Newborns: Enrollment Experience from the BabySeq Project (2018) (47)
- Attitudes about regulation among direct-to-consumer genetic testing customers. (2013) (46)
- Disclosing Secondary Findings from Pediatric Sequencing to Families: Considering the “Benefit to Families” (2015) (46)
- The future of direct-to-consumer clinical genetic tests (2011) (45)
- Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk EstimatesCLINICAL PERSPECTIVE (2016) (45)
- Vascular risk factors and neuropsychiatric symptoms in Alzheimer's disease: the Cache County Study (2014) (45)
- Differences between African Americans and Whites in their attitudes toward genetic testing for Alzheimer's disease. (2003) (44)
- Education attenuates the effect of medial temporal lobe atrophy on cognitive function in Alzheimer's disease: the MIRAGE study. (2009) (44)
- Age-at-Onset in Late Onset Alzheimer Disease is Modified by Multiple Genetic Loci (2014) (44)
- Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts (2016) (44)
- Changes to perceptions of the pros and cons of genetic susceptibility testing after APOE genotyping for Alzheimer disease risk (2011) (43)
- Calibrating Longitudinal Cognition in Alzheimer's Disease Across Diverse Test Batteries and Datasets (2014) (42)
- Education effects on cognitive function in a healthy aged Arab population (2006) (42)
- Geriatric Performance on an Abbreviated Version of the Boston Naming Test (2007) (42)
- A One-Page Summary Report of Genome Sequencing for the Healthy Adult (2015) (41)
- Participants and Study Decliners’ Perspectives About the Risks of Participating in a Clinical Trial of Whole Genome Sequencing (2016) (41)
- Design, methods, and participant characteristics of the Impact of Personal Genomics (PGen) Study, a prospective cohort study of direct-to-consumer personal genomic testing customers (2014) (41)
- Comparing test-specific distress of susceptibility versus deterministic genetic testing for Alzheimer's disease (2008) (40)
- Common folate gene variant, MTHFR C677T, is associated with brain structure in two independent cohorts of people with mild cognitive impairment☆ (2012) (40)
- Screening for cognitive impairment in older individuals. Validation study of a computer-based test. (1994) (40)
- Test–retest stability on the WRAT-3 reading subtest in geriatric cognitive evaluations (2009) (39)
- A collaborative translational research framework for evaluating and implementing the appropriate use of human genome sequencing to improve health (2018) (39)
- Using AD biomarker research results for clinical care (2013) (39)
- Rarity of the Alzheimer disease-protective APP A673T variant in the United States. (2015) (39)
- The Impact of Whole-Genome Sequencing on the Primary Care and Outcomes of Healthy Adult Patients: A Pilot Randomized Trial. (2017) (39)
- Personalized Risk Estimator for Rheumatoid Arthritis (PRE-RA) Family Study: rationale and design for a randomized controlled trial evaluating rheumatoid arthritis risk education to first-degree relatives. (2014) (38)
- Cognitive correlates of HVOT performance differ between individuals with mild cognitive impairment and normal controls. (2006) (38)
- Effects of Food and Drug Administration-approved medications for Alzheimer’s disease on clinical progression (2012) (38)
- Predispositional genome sequencing in healthy adults: design, participant characteristics, and early outcomes of the PeopleSeq Consortium (2019) (37)
- Disclosing Pleiotropic Effects During Genetic Risk Assessment for Alzheimer Disease: A Randomized Trial. (2016) (37)
- Interaction between vascular factors and the APOE ε4 allele in predicting rate of progression in Alzheimer's disease. (2011) (37)
- Genetic testing, insurance discrimination and medical research: what the United States can learn from peer countries (2019) (36)
- Perceived Benefits, Risks, and Utility of Newborn Genomic Sequencing in the BabySeq Project (2019) (36)
- Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer’s Disease (2017) (36)
- Adopting Genetics: Motivations and Outcomes of Personal Genomic Testing in Adult Adoptees (2015) (36)
- Communication challenges for nongeneticist physicians relaying clinical genomic results. (2017) (36)
- Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience (2008) (36)
- 'Someday it will be the norm': physician perspectives on the utility of genome sequencing for patient care in the MedSeq Project. (2015) (36)
- Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics (2019) (35)
- Disclosing the Disclosure: Factors Associated With Communicating the Results of Genetic Susceptibility Testing for Alzheimer's Disease (2009) (35)
- Utilization of Genetic Counseling after Direct-to-Consumer Genetic Testing: Findings from the Impact of Personal Genomics (PGen) Study (2017) (35)
- Diagnostic utility of the NAB List Learning test in Alzheimer’s disease and amnestic mild cognitive impairment (2009) (35)
- Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease (2012) (35)
- Large-scale genomics unveil polygenic architecture of human cortical surface area (2015) (34)
- Returning a Genomic Result for an Adult-Onset Condition to the Parents of a Newborn: Insights From the BabySeq Project (2019) (34)
- Heritability of Magnetic Resonance Imaging (MRI) Traits in Alzheimer Disease Cases and Their Siblings in the MIRAGE Study (2007) (34)
- Poster Presentations P1 P192 P1-067 THE MEASUREMENT OF EVERYDAY COGNITION (ECOG): DEVELOPMENT AND VALIDATION OF A SHORT VERSION (34)
- Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. (2015) (34)
- Recall of disclosed Apolipoprotein E genotype and lifetime risk estimate for Alzheimer's disease: The REVEAL Study (2006) (34)
- Prescription medication changes following direct-to-consumer personal genomic testing: Findings from the Impact of Personal Genomics (PGen) Study (2016) (33)
- FASTKD2 is associated with memory and hippocampal structure in older adults (2014) (33)
- The Project Baseline Health Study: a step towards a broader mission to map human health (2020) (33)
- Discordant results between conventional newborn screening and genomic sequencing in the BabySeq Project (2021) (33)
- Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk (2016) (33)
- Personal Genomic Testing for Cancer Risk: Results From the Impact of Personal Genomics Study. (2017) (33)
- Differences Between African American and White Research Volunteers in Their Attitudes, Beliefs and Knowledge Regarding Genetic Testing for Alzheimer’s Disease (2011) (33)
- Variants in PPP3R1 and MAPT are associated with more rapid functional decline in Alzheimer's disease: The Cache County Dementia Progression Study (2014) (33)
- When bins blur: Patient perspectives on categories of results from clinical whole genome sequencing (2017) (32)
- Analyzing and Reanalyzing the Genome: Findings from the MedSeq Project. (2019) (31)
- Caregiver personality predicts rate of cognitive decline in a community sample of persons with Alzheimer's disease. The Cache County Dementia Progression Study (2013) (31)
- Early detection of Alzheimer disease: methods, markers, and misgivings. (1997) (31)
- Dysnomia in Alzheimer's disease: An evaluation of neurobehavioral subtypes (1992) (31)
- An eMERGE Clinical Center at Partners Personalized Medicine (2016) (30)
- Reliability of Information Collected by Proxy in Family Studies of Alzheimer’s Disease (2001) (30)
- Navigating the research–clinical interface in genomic medicine: analysis from the CSER Consortium (2017) (30)
- Explaining, not just predicting, drives interest in personal genomics (2015) (30)
- Parents' Preferences for Return of Results in Pediatric Genomic Research (2014) (30)
- Parents are interested in newborn genomic testing during the early postpartum period (2014) (30)
- A randomized noninferiority trial of condensed protocols for genetic risk disclosure of Alzheimer's disease (2015) (30)
- A New Scale Measuring Psychologic Impact of Genetic Susceptibility Testing for Alzheimer Disease (2009) (29)
- Associations between self-referral and health behavior responses to genetic risk information (2015) (29)
- Diagnostic Accuracy Statistics for Seven Neuropsychological Assessment Battery (NAB) Test Variables in the Diagnosis of Alzheimer's Disease (2012) (29)
- Confirmatory Factor Analysis of the Mattis Dementia Rating Scale in Patients With Alzheimer's Disease (1996) (29)
- Returning Results in the Genomic Era: Initial Experiences of the eMERGE Network (2020) (29)
- A Randomized Controlled Trial of Disclosing Genetic Risk Information for Alzheimer’s Disease via Telephone (2017) (29)
- Summarizing polygenic risks for complex diseases in a clinical whole-genome report (2014) (29)
- Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide (2017) (28)
- Consumer Perspectives on Access to Direct‐to‐Consumer Genetic Testing: Role of Demographic Factors and the Testing Experience (2017) (28)
- Patients' perceived utility of whole-genome sequencing for their healthcare: findings from the MedSeq project. (2016) (28)
- Management of Incidental Findings in Clinical Genomic Sequencing (2015) (28)
- Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits (2016) (28)
- A first update on mapping the human genetic architecture of COVID-19 (2022) (27)
- Perceptions of Familial Risk in those Seeking a Genetic Risk Assessment for Alzheimer’s Disease (2009) (27)
- Magnetic Resonance Imaging Traits in Siblings Discordant for Alzheimer Disease (2008) (27)
- Women can bear a bigger burden: ante- and post-mortem evidence for reserve in the face of tau (2020) (26)
- Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (26)
- Assessment of Problem Solving and Executive Functions (1995) (26)
- Reclassification of genetic-based risk predictions as GWAS data accumulate (2016) (26)
- Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium (2018) (26)
- Explaining behavior change after genetic testing: the problem of collinearity between test results and risk estimates. (2008) (25)
- Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease (2021) (25)
- “Friendship” Interactions and Expression of Agitation among Residents of a Dementia Care Unit (2000) (25)
- Short Term Costs of Integrating Whole Genome Sequencing into Primary Care and Cardiology Settings: A Pilot Randomized Trial (2018) (24)
- O3-04-01: Safety and efficacy of tarenflurbil in subjects with mild Alzheimer's disease: Results from an 18-month multi-center phase 3 trial (2008) (24)
- Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease (2017) (24)
- Clinical utility of genomic sequencing: a measurement toolkit (2020) (24)
- Effectiveness of a condensed protocol for disclosing APOE genotype and providing risk education for Alzheimer disease (2012) (24)
- Design of a randomized trial of diabetes genetic risk testing to motivate behavior change: The Genetic Counseling/Lifestyle Change (GC/LC) Study for Diabetes Prevention (2011) (24)
- Use of Statins and Risk of Hospitalization With Dementia: A Danish Population-based Case-control Study (2009) (24)
- Navigating a research partnership between academia and industry to assess the impact of personalized genetic testing (2012) (24)
- Effect of communicating personalized rheumatoid arthritis risk on concern for developing RA: A randomized controlled trial (2018) (24)
- The impact of personal genomics on risk perceptions and medical decision-making (2016) (23)
- Diet and exercise changes following direct-to-consumer personal genomic testing (2017) (23)
- Diet and exercise changes following direct-to-consumer personal genomic testing (2017) (23)
- Brain levels of lutein (L) and zeaxanthin (Z) are related to cognitive function in centenarians (2011) (23)
- The impact of direct-to-consumer personal genomic testing on perceived risk of breast, prostate, colorectal, and lung cancer: findings from the PGen study (2015) (23)
- Predictors of subjective memory complaint in cognitively normal relatives of patients with Alzheimer's disease. (2006) (23)
- Prioritizing Disease‐Linked Variants, Genes, and Pathways with an Interactive Whole‐Genome Analysis Pipeline (2014) (22)
- Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease (2021) (22)
- Racial minority group interest in direct-to-consumer genetic testing: findings from the PGen study (2017) (22)
- CORRIGENDUM: ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing (2017) (22)
- Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer’s disease (2016) (22)
- Automated typing of red blood cell and platelet antigens from whole exome sequences (2019) (22)
- Development of a clinical polygenic risk score assay and reporting workflow (2022) (22)
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- 18F-florbetapir Positron Emission Tomography–determined Cerebral &bgr;-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery (2018) (21)
- Research Results: Preserving Newborn Blood Samples (2012) (21)
- The Development of a Preference-Setting Model for the Return of Individual Genomic Research Results (2015) (21)
- Reconciling Opportunistic and Population Screening in Clinical Genomics (2019) (21)
- Genomic medicine in the military (2016) (21)
- Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer’s Disease via Fusion of Clinical, Imaging and Omic Features (2017) (20)
- Effectiveness of a Web‐Based Personalized Rheumatoid Arthritis Risk Tool With or Without a Health Educator for Knowledge of Rheumatoid Arthritis Risk Factors (2018) (20)
- Participant Satisfaction With a Preference-Setting Tool for the Return of Individual Research Results in Pediatric Genomic Research (2015) (20)
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- Psychosocial Effect of Newborn Genomic Sequencing on Families in the BabySeq Project: A Randomized Clinical Trial. (2021) (19)
- KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease (2021) (19)
- Disclosing genetic risk for coronary heart disease: effects on perceived personal control and genetic counseling satisfaction (2016) (19)
- Direct-to-consumer genetic testing: reliable or risky? (2011) (18)
- Precision Population Medicine in Primary Care: The Sanford Chip Experience (2021) (18)
- How behavioral economics can help to avoid ‘The last mile problem’ in whole genome sequencing (2015) (18)
- Muscle cell growth and the distribution of water and electrolyte in human pregnancy. (1985) (18)
- Psychosocial Factors Influencing Parental Interest in Genomic Sequencing of Newborns (2016) (18)
- Preferences for the Return of Individual Results From Research on Pediatric Biobank Samples (2017) (18)
- Polygenic risk scores in the clinic: Translating risk into action (2021) (18)
- Comparison of multi-sample variant calling methods for whole genome sequencing (2014) (17)
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- Predicting cognitive decline and conversion to Alzheimer’s disease in older adults using the NAB List Learning test (2010) (17)
- Returning actionable genomic results in a research biobank: Analytic validity, clinical implementation, and resource utilization (2021) (17)
- Genome‐wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways (2020) (16)
- Genetic susceptibility testing for chronic disease and intention for behavior change in healthy young adults (2013) (16)
- Plasma phosphorylated-tau181 as a predictive biomarker for Alzheimer’s amyloid, tau and FDG PET status (2021) (16)
- Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways (2016) (16)
- Genetic susceptibility for Alzheimer's disease: Why did adult offspring seek testing? (2005) (16)
- Disclosing genetic risk of Alzheimer's disease to cognitively impaired patients and visit companions: Findings from the REVEAL Study. (2017) (16)
- Primary prevention trials in Alzheimer disease (2006) (16)
- Profiles of Cognitive Functioning in a Population-Based Sample of Centenarians Using Factor Mixture Analysis (2013) (15)
- Genomic medicine in primary care: barriers and assets (2013) (15)
- An analysis of test bias and differential item functioning due to race on the Mattis Dementia Rating Scale. (1998) (15)
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- An international policy on returning genomic research results (2021) (15)
- Cost Analyses of Genomic Sequencing: Lessons Learned from the MedSeq Project. (2018) (15)
- Disclosing genetic risk for Alzheimer's dementia to individuals with mild cognitive impairment (2020) (15)
- RHD Zygosity Determination from Whole Genome Sequencing Data (2016) (15)
- Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer’s Dementia (2018) (15)
- Effect of Pharmacogenetic Testing for Statin Myopathy Risk vs Usual Care on Blood Cholesterol (2020) (14)
- A genome sequencing system for universal newborn screening, diagnosis, and precision medicine for severe genetic diseases (2022) (14)
- Implications of Personal Genomic Testing for Health Behaviors: The Case of Smoking. (2016) (14)
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- How Primary Care Providers Talk to Patients about Genome Sequencing Results: Risk, Rationale, and Recommendation (2018) (13)
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- Approaches to carrier testing and results disclosure in translational genomics research: The clinical sequencing exploratory research consortium experience (2018) (13)
- “Big data” gets personal (2016) (12)
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- Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study (2021) (12)
- Safety and efficacy of tarenflurbil in subjects with mild Alzheimer's disease: Results from an 18-month international multi-center phase 3 trial (2009) (12)
- Challenging the Current Recommendations for Carrier Testing in Children (2019) (12)
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- DNA-based screening and personal health: a points to consider statement for individuals and health-care providers from the American College of Medical Genetics and Genomics (ACMG) (2021) (11)
- Pragmatic Tools for Sharing Genomic Research Results with the Relatives of Living and Deceased Research Participants (2018) (11)
- A whole genome approach for discovering the genetic basis of blood group antigens: independent confirmation for P1 and Xga (2018) (11)
- Universal newborn genetic screening for pediatric cancer predisposition syndromes: model-based insights (2021) (11)
- Reducing False‐Positive Incidental Findings with Ensemble Genotyping and Logistic Regression Based Variant Filtering Methods (2014) (11)
- Association of Pathogenic Variants in Hereditary Cancer Genes With Multiple Diseases. (2022) (11)
- A randomized trial of the clinical utility of genetic testing for obesity: Design and implementation considerations (2014) (11)
- Management of Incidental Findings in Clinical Genomic Sequencing (2013) (11)
- The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum (2016) (10)
- Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics (2013) (10)
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- Physician-directed genetic screening to evaluate personal risk for medically actionable disorders: a large multi-center cohort study (2021) (10)
- Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease (2021) (9)
- Areas of intervention for genetic counselling of dementia: cross-cultural comparison between Italians and Americans. (2006) (9)
- The structure and validity of self-reported affect in mild cognitive impairment and mild Alzheimer's disease (2011) (9)
- Genetic counseling following direct‐to consumer genetic testing: Consumer perspectives (2020) (9)
- Diagnosis and Management of Alzheimer's Disease and Other Dementias (2001) (9)
- Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease (2022) (9)
- FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease (2020) (9)
- APOE ϵ4, rated life experiences, and affect among centenarians (2014) (8)
- A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease (2020) (8)
- Factors Affecting Recall of Different Types of Personal Genetic Information about Alzheimer's Disease Risk: The REVEAL Study (2015) (8)
- Successful Recruitment of Centenarians for Post-Mortem Brain Donation: Results from the Georgia Centenarian Study. (2012) (8)
- The price of whole-genome sequencing may be decreasing, but who will be sequenced? (2017) (8)
- Biobanks could identify medically actionable findings relevant for COVID-19 clinical care (2020) (8)
- Correlation between Alzheimer’s disease and type 2 diabetes using non-negative matrix factorization (2021) (7)
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- Educating military primary health-care providers in genomic medicine: lessons learned from the MilSeq Project (2020) (7)
- Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine. (2016) (7)
- Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer (2020) (7)
- An Economic Interpretation of Taniwha Pa, Lower Waikato, New Zealand (N52/1) (2009) (7)
- Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community‐engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4 (2022) (6)
- Predictive and Precision Medicine with Genomic Data. (2019) (6)
- Correction: A collaborative translational research framework for evaluating and implementing the appropriate use of human genome sequencing to improve health (2018) (6)
- Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume (2022) (6)
- Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease (2022) (6)
- Alzheimer’s disease; clinical genomics: Practical applications in adult patient care (2013) (6)
- The impact of genetic counselors' use of facilitative strategies on cognitive and emotional processing of genetic risk disclosure for Alzheimer's disease. (2017) (6)
- Molecular cancer screening: in search of evidence (2021) (6)
- The Project Baseline Health Study: a step towards a broader mission to map human health. (2020) (6)
- Predicting Alzheimer’s disease progression using multi-modal deep learning approach (2019) (6)
- Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference (2018) (6)
- Reconciling newborn screening and a novel splice variant in BTD associated with partial biotinidase deficiency: a BabySeq Project case report (2018) (6)
- Multiple GYPB gene deletions associated with the U− phenotype in those of African ancestry (2020) (6)
- Interaction between vascular factors and the APOE E4 allele predict rate of progression in Alzheimer's dementia (2011) (5)
- The ADNI Publication Policy: Commensurate recognition of critical contributors who are not authors (2012) (5)
- Family Health History Reporting is Sensitive to Small Changes in Wording (2016) (5)
- The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory (2019) (5)
- In the Early Postpartum Period, Parents are Interested in Newborn Genomic Testing (2014) (5)
- Quantifying Downstream Healthcare Utilization in Studies of Genomic Testing. (2020) (5)
- An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease (2022) (5)
- Do research participants share genomic screening results with family members? (2021) (5)
- The case for implementing sustainable routine, population-level genomic reanalysis (2019) (5)
- APOE Genotype Disclosure for Risk of Alzheimer ’ s Disease : The REVEAL Study (2009) (5)
- O2-01-08 Comparing the impact of a condensed vs extended protocol for disclosure of APOE to relatives of patients with AD: The reveal study (2007) (5)
- Improved provider preparedness through an 8-part genetics and genomic education program. (2021) (4)
- Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients (2022) (4)
- The reckoning: The return of genomic results to 1444 participants across the eMERGE3 Network. (2022) (4)
- Enhancing Autonomy in Biobank Decisions: Too Much of a Good Thing? (2018) (4)
- P-004 Incorporating ethnicity into genetic risk assessment for Alzheimer’s disease: The reveal study experience (2007) (4)
- Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts (2016) (4)
- Behavioral and psychological impact of genome sequencing: a pilot randomized trial of primary care and cardiology patients (2021) (4)
- Muscle cell potassium, RNA and hydration in pregnancy and pre-eclampsia. (1989) (4)
- Commentary on “Illness Representations Among First-Degree Relatives of People With Alzheimer Disease” (2000) (4)
- Communication Predictors of Patient and Companion Satisfaction with Alzheimer’s Genetic Risk Disclosure (2018) (4)
- Clinical Practices Regarding Mild Cognitive Impairment (MCI) Among Neurology Service Providers (2009) (4)
- Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90 (2022) (4)
- Placebos in clinical trials in Alzheimer disease: an international discussion. (1999) (4)
- Reinventing submarine signature measurements: Installation of the High Gain Measurement System at SEAFAC (2009) (3)
- P4-121 How does genetic testing affect anxiety about developing ad? Findings from a randomized clinical trial (2004) (3)
- Low frequency of treatable pediatric disease alleles in gnomAD: An opportunity for future genomic screening of newborns (2021) (3)
- Parental Attitudes Toward Standard Newborn Screening and Newborn Genomic Sequencing: Findings From the BabySeq Study (2022) (3)
- Correction: Secondary findings from clinical genomic sequencing: prevalence, patient perspectives, family history assessment, and health-care costs from a multisite study (2019) (3)
- Primary care providers’ responses to unsolicited Lynch syndrome secondary findings of varying clinical significance (2021) (3)
- Design, methods, and participant characteristics of the Impact of Personal Genomics (PGen) Study, a prospective cohort study of direct-to-consumer personal genomic testing customers (2014) (3)
- Are we prepared to deliver gene‐targeted therapies for rare diseases? (2023) (3)
- Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology (2020) (3)
- Development and Validation of a Comprehensive Genomics Knowledge Scale (2021) (3)
- Airmen and Healthcare Providers’ attitudes toward the use of genomic sequencing in the US Air Force: Findings from the MilSeq Project (2020) (3)
- Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy (2021) (3)
- Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease (2020) (3)
- Glucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment (2022) (3)
- S1-03-03 Pooled analysis of the association between different NSAIDS and AD: preliminary findings (2004) (3)
- A Framework for Automated Gene Selection in Genomic Applications (2021) (3)
- Aging, biotechnology, and the future (2008) (2)
- Effects of participation in a U.S. trial of newborn genomic sequencing on parents at risk for depression (2021) (2)
- Influence of rare reelin variants on quantitative PET imaging and CSF phenotypes in late-onset Alzheimer’s disease (2015) (2)
- ERRATUM: Processes and preliminary outputs for identification of actionable genes as incidental findings in genomic sequence data in the Clinical Sequencing Exploratory Research Consortium (2014) (2)
- The formation of the advisory group on risk evaluation education for dementia (2020) (2)
- Genome-wide rare variant analysis identifies candidate genes significantly associated with composite scores for memory (2015) (2)
- Incorporating ethnicity into genetic risk assessment for Alzheimer's disease: the REVEAL study (2008) (2)
- Erratum: Correction: A collaborative translational research framework for evaluating and implementing the appropriate use of human genome sequencing to improve health (PLoS medicine (2018) 15 8 (e1002631)) (2018) (2)
- The psychological impact of genetic risk information on individuals with mild cognitive impairment at imminent risk for conversion to Alzheimer's disease dementia: Findings from the REVEAL Study (2013) (2)
- TOMM40 Variable Length Polymorphism is Associated With Memory Function in Asymptomatic Middle-aged Persons (2010) (2)
- Beliefs about prevention and treatment of Alzheimer’s disease among African Americans (2005) (2)
- Planar cell polarity pathway and development of the human visual cortex (2018) (2)
- Tomm40 is Associated with Gray Matter Volume in Middle-aged Persons with Apoe ɛ3/ɛ3 Genotype (2010) (2)
- Moving away from one disease at a time: Screening, trial design, and regulatory implications of novel platform technologies (2023) (2)
- Improving Access to HLA-Matched Kidney Transplants for African American Patients (2022) (2)
- Non-Alzheimer's degenerative dementias (1995) (2)
- Imaging genetics of the SPON1 gene variant rs11023139 in Alzheimer's disease (2013) (2)
- Long-awaited progress in addressing genetic discrimination in the United States (2020) (2)
- Minding the aging brain: are we ready for personalized medicine? (2014) (2)
- Challenges in the Clinical Use of Genome Sequencing (2012) (2)
- The psychological impact of learning about APOE-cardiovascular disease associations during genetic risk assessment for Alzheimer's disease: Findings from the reveal study (2010) (2)
- Genetic findings using ADNI multimodal quantitative phenotypes: A 2014 update (2015) (2)
- Clinical validation, implementation, and reporting of polygenic risk scores for common diseases (2021) (2)
- P2-282: Impact of a condensed protocol for disclosing APOE genotype to first-degree relatives of people with Alzheimer's disease (2008) (2)
- Correction: Long-awaited progress in addressing genetic discrimination in the United States (2020) (1)
- Postmenopausal estrogen reduced the risk for and delayed the onset of Alzheimer disease (1997) (1)
- ASSESSING THE IMPACT OF DISCLOSING AMYLOID IMAGING RESULTS TO COGNITIVELY NORMAL OLDER ADULTS: THE REVEAL-SCAN STUDY (2017) (1)
- Patient and provider perspectives on polygenic risk scores: implications for clinical reporting and utilization (2022) (1)
- Heritability of regional brain volumes in large-scale neuroimaging and genetic studies (2017) (1)
- Disclosing ApoE genotype status to individuals at risk for Alzheimer's disease: Applying lessons learned from the reveal study to prevention treatment trials (2015) (1)
- Predictors of progression through the recruitment process, from questionnaire response to enrollment, in an Alzheimer’s disease (AD) primary prevention trial (2005) (1)
- Interaction between C-Reactive protein level and APOE genotype in predicting rate of progression in Alzheimer's disease: The Cache County dementia progression study (2009) (1)
- Support for Genetic Association Between Variants in PPP3R1 and MAPT and Rate of Progression of Alzheimer’s Disease (2011) (1)
- DIRECT-TO-CONSUMER GENETIC TESTING FOR RISK OF ALZHEIMER'S DISEASE (AD): THE PSYCHOLOGICAL AND BEHAVIORAL IMPACT OF APOE GENOTYPE DISCLOSURE (2014) (1)
- Alzheimer’s disease – Modernizing concept, biological diagnosis and therapy (2011) (1)
- P2-338 Evaluating the efficacy of a caregiver-based, behavioral intervention for reducing neuropsychiatric symptoms among patients with Alzheimer's disease and for reducing caregiver distress: a controlled trial (2004) (1)
- The PRECISE Pilot Trial: Temporal Changes In Thrombin Generation, Protein C Levels And Activated Protein C Generation In Early Septic Shock (2010) (1)
- STRIATAL PLAQUES OCCUR RELATIVELY EARLY IN THE PROGRESSION OF ALZHEIMERʼS DISEASE CHANGES: 63 (1995) (1)
- Injury and Disease Linkages Effects of traumatic brain injury and posttraumatic stress disorder on Alzheimer's disease in veterans, using the Alzheimer's Disease Neuroimaging Initiative * (2014) (1)
- O2-01-08: Assocation between neuropsychiatric syndromes and mortality in a population-based sample of incident Alzheimer's disease and other dementias: The Cache County dementia progression study (2008) (1)
- What is the experience of being an APOE-ε4 homozygote? Findings from the REVEAL Study (2013) (1)
- Reevaluating the "right not to know" in genomics research. (2021) (1)
- SS-FDMA channelization and routing in advanced multibeam mobile satellite systems (1988) (1)
- Parents' decision-making regarding whether to receive adult-onset only genetic findings for their children: Findings from the BabySeq Project. (2022) (1)
- P4-376: A phase 3 multicenter trial of tarenflurbil in subjects with mild dementia of the Alzheimer's type (Act-Earli-AD): Rationale and methodology (2008) (1)
- Author Correction: Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease (2021) (1)
- THE EVOLVING ROLE OF MEDICAL GENETICISTS IN THE ERA OF GENE THERAPY: AN URGENCY TO PREPARE. (2023) (1)
- Genetic architecture of subcortical brain structures in 38,851 individuals (2019) (1)
- Using APOE to predict “imminent” risk of Alzheimer's disease conversion among patients with MCI: The REVEAL Study (2010) (1)
- P3-168 APOE, vascular pathology, and the AD brain (2004) (1)
- P2-240: Development of a new scale measuring psychological impact of genetic susceptibility testing for Alzheimer's disease (2008) (1)
- Using the capacity assessment tool for genetic testing (CAT-GT) to assess the ability of persons with MCI to decide about ApoE testing: The reveal study (2015) (1)
- Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease (2018) (0)
- Enabling Personalized Medicine Through Exome Sequencing in the U.S. Air Force (2018) (0)
- S2-01-02 Using a genetic approach to understand the vascular basis of Alzheimer disease (2004) (0)
- Worldwide ADNI Update – July , 2012 (2013) (0)
- P 3 P 3001 MITOCHONDRIAL GENOME-WIDE ASSOCIATION STUDYOFALZHEIMER ’ S DISEASE (2013) (0)
- Parity of Patient and Provider Perceptions of Omics-Integrated Military Medicine (Poster) (2018) (0)
- Comparison of statistical models estimating rate of decline in a population-based cohort of persons with Alzheimer's disease: The Cache County study (2011) (0)
- Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers (2013) (0)
- Low frequency of treatable pediatric disease alleles in gnomAD: an opportunity for future genomic newborn screening (2021) (0)
- Influence of rare RELN variants on quantitative PET imaging and CSF phenotypes in late-onset Alzheimer’s disease (2015) (0)
- Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer’s disease (2016) (0)
- Supplementary Material for: Calibrating Longitudinal Cognition in Alzheimer's Disease Across Diverse Test Batteries and Datasets (2017) (0)
- Impact of Genetic Testing for Alzheimer’s Disease (2019) (0)
- P-199 Use of anti-cholinesterase inhibitors and memantine in a population-based study of incident AD cases: Prevalence of use, characteristics, and relationship to mortality (2007) (0)
- O4‐04‐06: Withdrawn (2015) (0)
- Parental survey of interest in newborn genome screening research (2013) (0)
- RARE VARIANT IN PLD3 IS ASSOCIATED WITH ALZHEIMER'S PATTERN OF NEURODEGENERATIVE CHANGES (2014) (0)
- Special Considerations for Genomic Sequencing Research in the United States Air Force: Development of the MilSeq Project (2017) (0)
- Contens Vol. 43, 2014 (2015) (0)
- P1-158 Alzheimer’s disease in centenarians: Clinicopathologic correlations in the georgia centenarian study (2006) (0)
- A Framework for Automated Gene Selection in Genomic Screening (2020) (0)
- INFLUENCE OF RARE PSEN1 VARIANTS ON QUANTITATIVE STRUCTURAL IMAGING AND CSF PHENOTYPES IN LATE ONSET ALZHEIMER'S DISEASE (2014) (0)
- P2-060: Comparison of Alzheimer and vascular dementia patients using MRI-based measures of atrophy (2008) (0)
- O1-02-04 Higher self-perceived risk of Alzheimer’s disease is associated with lower dropout in a study disclosing genetic susceptibility (2007) (0)
- Featured Article A randomized noninferiority trial of condensed protocols for genetic risk disclosure of Alzheimer's disease (2015) (0)
- P4-372: Comparison of a slopes analysis using a mixed model to a traditional change from baseline analysis in an Alzheimer's disease clinical trial setting (2008) (0)
- munoassays for the clinical diagnostic work-up of AD. P4-069 DEVELOPMENT OFA PROCESS TO DISCLOSE AMYLOID IMAGING RESULTS TO COGNITIVELY NORMAL OLDER ADULT RESEARCH PARTICIPANTS (2014) (0)
- Orientation in patients with alzheimer's disease (1997) (0)
- Combination Therapy of Albumin and Furosemide To Induce a Negative Fluid Balance: A Systematic Review of the Literature. (2009) (0)
- P3-052: Neuropsychiatric syndromes in Alzheimer's disease: Relationship to cognitive and functional progression. The Cache County dementia progression study (2008) (0)
- P4-200 The psychological impact of susceptibility versus deterministic genetic testing for Alzheimer’s disease (2006) (0)
- Association between serum and brain fatty acid profiles in centenarians (821.2) (2014) (0)
- A New Model for Genomics Support of Military Healthcare Providers: Early Findings from the MilSeq Project (2018) (0)
- P1-273 Extended versus condensed protocol for disclosing genetic susceptibility for Alzheimer’s disease: The REVEAL Study (2006) (0)
- Development of a genetic education and genetic risk disclosure protocol for individuals with mild cognitive impairment (2011) (0)
- Common folate genevariant , MTHFR C 677 T , is associatedwithbrain structure in two independent cohorts of people with mild cognitive impairment ☆ (2013) (0)
- The Cost Of Integrating Whole Genome Sequencing Into The Care Of Cardiomyopathy Patients: Sensitivity And Scenario Analyses (2018) (0)
- A scalable EHR-based approach for phenotype discovery and variant interpretation for hereditary cancer genes (2021) (0)
- P.5.c.003 Comparison of mixed model slope analysis with traditional change from baseline analysis, in an AD clinical trial setting (2008) (0)
- Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration (2020) (0)
- Gwas of longitudinal amyloid PET identifies IL1RAP as a new potential Alzheimer's disease target (2015) (0)
- Attitudes, knowledge and intentions about genetic testing among relatives of Italian patients affected by familial dementia: Cross-cultural comparison with Americans (2005) (0)
- P3-165 MRI traits are heritable among Alzheimer disease cases and their siblings in the MIRAGE Study (2006) (0)
- Gender modifying-effect between APOE and cognitive decline in Alzheimer's disease: The Cache County dementia progression study (2011) (0)
- P-157 Factors associated with the impact of susceptibility genetic testing of Alzheimer’s disease (2007) (0)
- A randomized trial examining recall and distress after telephone versus in-person disclosure of genetic risk information about Alzheimer's disease: the REVEAL study (2011) (0)
- P2-413 What motivates adult offspring of persons with Alzheimer's disease to seek susceptibility genetic testing? (2004) (0)
- Protective variant for rate of hippocampal volume loss identified by whole exome sequencing in APOE-ε3ε3 males with MCI (2013) (0)
- Impact of APOE Genotype Disclosure on Exercise and Mental Activities (2011) (0)
- 3 Cirino at al Comparing Panel and Whole Genome Sequencing in HCM Results Patient Characteristics (2017) (0)
- The trend of disruption in the functional brain network topology of Alzheimer’s disease (2021) (0)
- O2-06-08: Distinct variants in SORL1 are associated with cerebrovascular and neurodegenerative changes related to Alzheimer's disease (2008) (0)
- Whole-Genome Sequencing in Primary Care (2017) (0)
- Genome-wide analysis of genetic variants associated with depressive symptoms in older adults (2013) (0)
- Provision of Basic Genetic Counseling Services by Primary Healthcare Providers After an Educational Intervention: Lessons Learned from the Milseq Project (2020) (0)
- Is apoE plasma level associated with MCI? Findings from the Framingham Heart Study (2005) (0)
- Abstract 20188: The Effect of Disclosing Genetic Risk for Coronary Heart Disease on Perceived Personal Control and Genetic Counseling Satisfaction: The MI-GENES Study (2014) (0)
- P.5.b.003 Apolipoprotein E disclosure for genetic risk assessment of Alzheimer's disease: preparing for pharmacogenetics (2008) (0)
- False Reassurance Following Genetic Susceptibility Testing for Alzheimer’s Disease: Evidence from the REVEAL Study (2011) (0)
- LATE BREAKING NEWS (2008) (0)
- ANOSOGNOSIA IN ALZHEIMER'S DISEASE. AUTHORS' REPLY (1996) (0)
- VKučinskas-2001-2016 (2016) (0)
- Purifying selection on noncoding deletions of human regulatory elements detected using their cellular pleiotropy (2020) (0)
- WHAT IS THE LONG-TERM EMOTIONAL AND BEHAVIORAL IMPACT OF GENETIC RISK ASSESSMENT FOR ALZHEIMER'S DISEASE? FINDINGS FROM THE REVEAL STUDY (2014) (0)
- Genetic Risk Counseling to Motivate Diabetes Prevention (2012) (0)
- Development of a process to disclose amyloid imaging results to cognitively normal older adult research participants (2015) (0)
- RARE VARIANT IN PLD3 IS ASSOCIATED WITH ALZHEIMER'S PATTERN OF NEURODEGENERATIVE CHANGES (2014) (0)
- Family history of non-Alzheimer's Demeutia memory problems predicts rate of cognitive decline in APOE E4 non-carriers in Alzheimer's disease: The Cache County Dementia Progression Study. (2011) (0)
- NEXT-GENERATION SEQUENCING OF THE BCHE LOCUS IDENTIFIES A FUNCTIONAL SNP ASSOCIATED WITH ALZHEIMER'S DISEASE BIOMARKERS AND AGE OF ONSET (2014) (0)
- Medical consequences of unanticipated monogenic findings identified through exome screening of newborns in the BabySeq Project (2021) (0)
- Quantifying an emerging ethical responsibility Disclosing pathogenic genetic variants to research participants : Material Supplemental (2012) (0)
- PMU116 - PATIENT-REPORTED OUTCOMES IN A PILOT RANDOMIZED TRIAL OF GENOME SEQUENCING (2018) (0)
- P3-488: The impact of an education and risk evaluation protocol on perceived benefits and risks of genetic susceptibility testing for Alzheimer's disease (2008) (0)
- The PRECISE Fluid Resuscitation Pilot Randomized Controlled Trial: Study Design And Preliminary Feasibility Results (2010) (0)
- ASSOCIATION ANALYSIS OF RARE VARIANTS NEAR THE APOE REGION WITH CEREBROSPINAL FLUID (CSF) BIOMARKERS OF ALZHEIMER'S DISEASE (2014) (0)
- ImpactoftheAlzheimer'sDiseaseNeuroimagingInitiative,2004to2014 (2015) (0)
- Author Correction: Multimodal hippocampal subfield grading for Alzheimer’s disease classification (2020) (0)
- P4-201 Age group differences in response to genetic risk assessment: Results from the risk evaluation & education for Alzheimer’s disease (REVEAL) study (2006) (0)
- Acta Neuropathologica ABCC 9 gene polymorphism is associated with hippocampal sclerosis of aging pathology (2017) (0)
- Identification of genetic variants associated with Alzheimer's disease: Progression rate (2015) (0)
- Pharmacogenomics in the U.S. Air Force: Development of a Tailored Panel for the MilSeq Project (2018) (0)
- Title Large-scale genomics unveil polygenic architecture of human cortical surface area Permalink (2015) (0)
- P3-133: The diagnostic utility of the NAB list learning test in the assessment of Alzheimer's disease and mild cognitive impairment (2008) (0)
- P1-209: Cognitive complaints in mild cognitive impairment and Alzheimer's disease (2008) (0)
- A Randomized Non-inferiority Trial of Condensed Protocols for Genetic Risk Disclosure of Alzheimer ’ s Disease (2015) (0)
- Integrating whole-exome sequencing and imaging genetics to identify single-nucleotide variants associated with rate of hippocampal neurodegeneration in APOE-ε3/ε3 males with mild cognitive impairment (2012) (0)
- Book Reviews (2001) (0)
- Research Article Variants in PPP3R1 and MAPTare associated with more rapid functional decline inAlzheimer's disease: TheCache County Dementia Progression Study (2013) (0)
- P1-283 Ethnic differences in MRI scans among Alzheimer’s disease patients and unaffected siblings in the MIRAGE Study (2006) (0)
- Polymorphisms in paraoxonase genes PON1, PON2 and PON3 are associated with late onset Alzheimer disease (2005) (0)
- Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer’s Dementia (2018) (0)
- Genetic factors associated with the rate of cognitive decline in Alzheimer's disease (2011) (0)
- Imaging genetics of SPON1 gene variant rs11023139 in Alzheimer's disease (2013) (0)
- The reveal study: The impact of genetic risk assessment with APOE disclosure for Alzheimer’s disease (2005) (0)
- Brain carotenoids and physical function in the very old (2011) (0)
- P3‐013: Withdrawn (2015) (0)
- Diabetes mellitus and risk of developing Alzheimer’s dementia: Results from the Framingham study (2005) (0)
- Binary vs. continuous: understanding provider and patient preference for polygenic risk score reporting (2021) (0)
- How knowledge of elevated amyloid impacts neuropsychological performance in cognitively normal older adults: Findings from the REVEAL SCAN Study (2021) (0)
- Willingness to Pay for Alzheimer’s Disease Genetic Susceptibility Testing: Results from the REVEAL Study (2011) (0)
- EDUCATING PATIENTS AND CARE PARTNERS ABOUT MILD COGNITIVE IMPAIRMENT, APOE, AND ALZHEIMER’S DISEASE: FINDINGS FROM THE REVEAL STUDY (2016) (0)
- 14th Italian Congress of Neuroepidemiology. Milan, Italy, November 21-22, 2014: Abstracts (2014) (0)
- Does hypertension affect the risk and age at onset of Alzheimer disease? (2000) (0)
- Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease (2017) (0)
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (0)
- Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease (2020) (0)
- Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study (2020) (0)
- Particle Loading Tests on HEPA Flat Sheet Media at Sub-Ambient Pressures Using a Lunar Dust Simulant (2021) (0)
- GenEpi: gene-based epistasis discovery using machine learning (2020) (0)
- Human leukocyte antigen distributions do not share a copula across sub-populations (2022) (0)
- Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty (2017) (0)
- The Relationship of Lutein and DHA in Cognitive Function (2013) (0)
- College Spread of COVID-19 in Ohio (2022) (0)
- P408: Perspectives of rare disease experts on sequencing newborns for treatable genetic conditions* (2023) (0)
- Disclosure of APOE genotype to persons with mild cognitive impairment (MCI) (2012) (0)
- P517: An automated approach to report drafting for newborn genomic sequencing in the BabySeq Project (2023) (0)
- Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer (2020) (0)
- Polygenic risk scores in the clinic: new perspectives needed on familiar ethical issues (2021) (0)
- Diet and exercise changes following direct-to-consumer personal genomic testing (2017) (0)
- Diet and exercise changes following direct-to-consumer personal genomic testing (2017) (0)
- Associations between self-referral and health behavior responses to genetic risk information (2015) (0)
- Educating military primary health-care providers in genomic medicine: lessons learned from the MilSeq Project (2020) (0)
- Workforce Considerations When Building a Precision Medicine Program (2022) (0)
- Prioritizing the detection of rare pathogenic variants in population screening (2023) (0)
- Reclassification of genetic-based risk predictions as GWAS data accumulate (2016) (0)
- The impact of direct-to-consumer personal genomic testing on perceived risk of breast, prostate, colorectal, and lung cancer: findings from the PGen study (2015) (0)
- A review of published genetic studies using ADNI multimodality quantitative phenotypes: MRI, PET, fluid biomarkers, cognition and clinical status (2013) (0)
- Return of Results in Genomic Research Using Large-Scale or Whole Genome Sequencing: Toward a New Normal. (2023) (0)
- Parental interest in genomic sequencing of newborns: enrollment experience from the BabySeq Project (2018) (0)
- Explaining, not just predicting, drives interest in personal genomics (2015) (0)
- A framework evaluating the utility of multi-gene, multi-disease population-based panel testing that accounts for uncertainty in penetrance estimates (2023) (0)
- P2-115 Factors associated with changing decisions for brain donation (2006) (0)
- Medical Evaluation of Unanticipated Monogenic Disease Risks Identified through Newborn Genomic Screening: Findings from the BabySeq Project (2022) (0)
- Public willingness to participate in population DNA screening in Australia (2022) (0)
- Racial minority group interest in direct-to-consumer genetic testing: findings from the PGen study (2017) (0)
- Patient understanding of, satisfaction with, and perceived utility of whole-genome sequencing: findings from the MedSeq Project (2018) (0)
- Awareness and utilization of genetic testing among Hispanic and Latino adults living in the US: The Hispanic Community Health Study/Study of Latinos (2022) (0)
- Short-term costs of integrating whole-genome sequencing into primary care and cardiology settings: a pilot randomized trial (2018) (0)
- Predispositional genome sequencing in healthy adults: design, participant characteristics, and early outcomes of the PeopleSeq Consortium (2019) (0)
- Author Correction: Multimodal hippocampal subfield grading for Alzheimer’s disease classification (2020) (0)
- An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery (2018) (0)
- A blood-based signature of cerebrospinal fluid Aβ1–42 status (2019) (0)
- Author Correction: FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease (2022) (0)
- Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics (2019) (0)
- Parental interest in genomic sequencing of newborns: enrollment experience from the BabySeq Project (2018) (0)
- Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction (2023) (0)
- Motivation for Seeking Genetic Risk Assessment for Alzheimer's Disease: Implications for Health Education (2011) (0)
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