Robert Clarke
#95,968
Most Influential Person Now
Northern Irish oncologist
Robert Clarke 's AcademicInfluence.com Rankings
Robert Clarke medical Degrees
Medical
#1590
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#1946
Historical Rank
Oncology
#73
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#77
Historical Rank
Robert Clarke philosophy Degrees
Philosophy
#7789
World Rank
#11045
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Logic
#4832
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#6161
Historical Rank
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Medical Philosophy
Robert Clarke 's Degrees
- Masters Medicine Queen's University Belfast
- Doctorate Oncology Queen's University Belfast
Why Is Robert Clarke Influential?
(Suggest an Edit or Addition)According to Wikipedia, Robert Clarke is a Northern Irish oncology researcher and academic administrator. He is the executive director of The Hormel Institute, a professor of biochemistry, Molecular Biology and Biophysics at the University of Minnesota, and an adjunct professor of oncology at Georgetown University.
Robert Clarke 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (2012) (6925)
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Aberrant Activation of Notch Signaling in Human Breast Cancer (2006) (557)
- Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland (2003) (549)
- Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines (1992) (548)
- The properties of high-dimensional data spaces: implications for exploring gene and protein expression data (2008) (516)
- Identification of a putative intestinal stem cell and early lineage marker; musashi-1. (2003) (506)
- Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling (2003) (485)
- Meta-analysis of soy intake and breast cancer risk. (2006) (475)
- Cellular and molecular pharmacology of antiestrogen action and resistance. (2001) (414)
- Endocrine resistance in breast cancer – An overview and update (2015) (276)
- A maternal diet high in n - 6 polyunsaturated fats alters mammary gland development, puberty onset, and breast cancer risk among female rat offspring. (1997) (273)
- Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer. (2011) (246)
- MCF7/LCC2: a 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780. (1993) (226)
- MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen. (1997) (213)
- Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate. (2012) (210)
- Prepubertal exposure to zearalenone or genistein reduces mammary tumorigenesis (1999) (202)
- Human X‐Box binding protein‐1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines (2007) (187)
- Maternal exposure to genistein during pregnancy increases carcinogen-induced mammary tumorigenesis in female rat offspring. (1999) (186)
- Progression of human breast cancer cells from hormone-dependent to hormone-independent growth both in vitro and in vivo. (1989) (185)
- Dynamic modelling of oestrogen signalling and cell fate in breast cancer cells (2011) (178)
- Hormonal aspects of breast cancer. Growth factors, drugs and stromal interactions. (1992) (156)
- Autophagy and endocrine resistance in breast cancer (2011) (152)
- Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness. (2012) (150)
- The effects of a constitutive expression of transforming growth factor-alpha on the growth of MCF-7 human breast cancer cells in vitro and in vivo. (1989) (141)
- Interferon regulatory factor-1 (IRF-1) exhibits tumor suppressor activities in breast cancer associated with caspase activation and induction of apoptosis. (2005) (135)
- Multidrug resistance/P-glycoprotein and breast cancer: review and meta-analysis. (2005) (130)
- Estrogen Withdrawal-Induced NF-κB Activity and Bcl-3 Expression in Breast Cancer Cells: Roles in Growth and Hormone Independence (2003) (129)
- Molecular and pharmacological aspects of antiestrogen resistance (2001) (125)
- Differential dependency network analysis to identify condition-specific topological changes in biological networks (2009) (123)
- Chloroquine Inhibits Autophagy to Potentiate Antiestrogen Responsiveness in ER+ Breast Cancer (2014) (117)
- Reduction of the membrane fluidity of human breast cancer cells by tamoxifen and 17 beta-estradiol. (1990) (110)
- Influence of berry polyphenols on receptor signaling and cell-death pathways: implications for breast cancer prevention. (2012) (108)
- Human breast cancer cell line xenografts as models of breast cancer — The immunobiologies of recipient mice and the characteristics of several tumorigenic cell lines (2005) (108)
- Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappaB, and cyclic AMP response element binding with acquired resistance to Faslodex (ICI 182,780). (2002) (107)
- Development and validation of a method for using breast core needle biopsies for gene expression microarray analyses. (2002) (105)
- Molecular mechanisms of tamoxifen-associated endometrial cancer (Review) (2015) (105)
- Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer. (2005) (98)
- Dietary modulation of pregnancy estrogen levels and breast cancer risk among female rat offspring. (2002) (97)
- Acquisition of hormone-independent growth in MCF-7 cells is accompanied by increased expression of estrogen-regulated genes but without detectable DNA amplifications. (1993) (94)
- ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer. (2008) (92)
- Resistance to TNF-alpha and adriamycin in the human breast cancer MCF-7 cell line: relationship to MDR1, MnSOD, and TNF gene expression. (1994) (91)
- Identification of twenty alternatively spliced estrogen receptor alpha mRNAs in breast cancer cell lines and tumors using splice targeted primer approach (2000) (91)
- Maternal genistein exposure mimics the effects of estrogen on mammary gland development in female mouse offspring. (1998) (90)
- Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b. (2006) (90)
- BCL2 and CASP8 regulation by NF‐κB differentially affect mitochondrial function and cell fate in antiestrogen‐sensitive and ‐resistant breast cancer cells (2010) (87)
- Breast cancer risk in rats fed a diet high in n-6 polyunsaturated fatty acids during pregnancy. (1996) (86)
- Identifying cancer biomarkers by network-constrained support vector machines (2011) (85)
- Reversal of tamoxifen resistance of human breast carcinomas in vivo by neutralizing antibodies to transforming growth factor-beta. (1999) (85)
- Common origins of MDA-MB-435 cells from various sources with those shown to have melonoma properties (2004) (84)
- Enhancing reproducibility in cancer drug screening: how do we move forward? (2014) (84)
- NTP-CERHR expert panel report on the developmental toxicity of soy infant formula. (2011) (83)
- Psychosocial factors in the development and progression of breast cancer (2004) (83)
- The nuclear factor κB inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)–induced apoptosis in antiestrogen-resistant breast cancer cells (2005) (83)
- The process of malignant progression in human breast cancer. (1990) (80)
- Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells (2009) (78)
- Knockdown of estrogen receptor‐α induces autophagy and inhibits antiestrogen‐mediated unfolded protein response activation, promoting ROS‐induced breast cancer cell death (2014) (78)
- Maternal and prepubertal diet, mammary development and breast cancer risk. (2001) (76)
- IFNγ Restores Breast Cancer Sensitivity to Fulvestrant by Regulating STAT1, IFN Regulatory Factor 1, NF-κB, BCL2 Family Members, and Signaling to Caspase-Dependent Apoptosis (2010) (75)
- Approaches to working in high-dimensional data spaces: gene expression microarrays (2008) (75)
- Interferon Regulatory Factor-1 Mediates the Proapoptotic but Not Cell Cycle Arrest Effects of the Steroidal Antiestrogen ICI 182,780 (Faslodex, Fulvestrant) (2004) (74)
- Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer. (2016) (73)
- Disruption of estrogen receptor DNA-binding domain and related intramolecular communication restores tamoxifen sensitivity in resistant breast cancer. (2006) (72)
- The influence of maternal diet on breast cancer risk among female offspring. (1999) (71)
- Two-dimensional gel electrophoresis analyses identify nucleophosmin as an estrogen regulated protein associated with acquired estrogen-independence in human breast cancer cells (1998) (71)
- The p160 family coactivators regulate breast cancer cell proliferation and invasion through autocrine/paracrine activity of SDF-1alpha/CXCL12. (2005) (69)
- Co-Inhibition of BCL-W and BCL2 Restores Antiestrogen Sensitivity through BECN1 and Promotes an Autophagy-Associated Necrosis (2010) (69)
- NF-κB Signaling Is Required for XBP1 (Unspliced and Spliced)-Mediated Effects on Antiestrogen Responsiveness and Cell Fate Decisions in Breast Cancer (2014) (69)
- Anti‐proliferative and anti‐estrogenic effects of ICI 164,384 and ICI 182,780 in 4‐OH‐tamoxifen‐resistant human breast‐cancer cells (1994) (68)
- Iterative normalization of cDNA microarray data (2002) (68)
- MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer (2014) (67)
- Classification algorithms for phenotype prediction in genomics and proteomics. (2008) (67)
- G-DOC: a systems medicine platform for personalized oncology. (2011) (66)
- The role of X-box binding protein-1 in tumorigenicity. (2009) (65)
- Caveolin-1 Tyrosine Phosphorylation Enhances Paclitaxel-mediated Cytotoxicity* (2007) (65)
- Do estrogens always increase breast cancer risk? (2002) (65)
- Dynamic Modeling of the Interaction Between Autophagy and Apoptosis in Mammalian Cells (2013) (64)
- Effect of P-glycoprotein expression on sensitivity to hormones in MCF-7 human breast cancer cells. (1992) (63)
- The nuclear factor kappa B inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells. (2005) (62)
- Gamma-tocotrienol induced apoptosis is associated with unfolded protein response in human breast cancer cells. (2012) (62)
- The inter-relationships between ovarian-independent growth, tumorigenicity, invasiveness and antioestrogen resistance in the malignant progression of human breast cancer. (1989) (61)
- Issues in experimental design and endpoint analysis in the study of experimental cytotoxic agents in vivo in breast cancer and other models (1997) (61)
- Maternal exposure to tamoxifen during pregnancy increases carcinogen-induced mammary tumorigenesis among female rat offspring. (2000) (60)
- Physical and Functional Interactions between Cas and cSrc Induce Tamoxifen Resistance of Breast Cancer Cells through Pathways Involving Epidermal Growth Factor Receptor and Signal Transducer and Activator of Transcription 5 b (2006) (59)
- Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy (2014) (59)
- Tyrosine-phosphorylated Caveolin-1 (Tyr-14) Increases Sensitivity to Paclitaxel by Inhibiting BCL2 and BCLxL Proteins via c-Jun N-terminal Kinase (JNK)* (2012) (57)
- Mathematical modelling of transcriptional heterogeneity identifies novel markers and subpopulations in complex tissues (2016) (55)
- GX15-070 (Obatoclax) Induces Apoptosis and Inhibits Cathepsin D- and L–Mediated Autophagosomal Lysis in Antiestrogen-Resistant Breast Cancer Cells (2013) (55)
- Endocrine therapy resistance can be associated with high estrogen receptor alpha (ERalpha) expression and reduced ERalpha phosphorylation in breast cancer models. (2006) (55)
- Estrogen receptor alpha positive breast tumors and breast cancer cell lines share similarities in their transcriptome data structures. (2006) (52)
- The invasive and metastatic properties of hormone-independent but hormone-responsive variants of MCF-7 human breast cancer cells (2004) (52)
- UNDO: a Bioconductor R package for unsupervised deconvolution of mixed gene expressions in tumor samples (2015) (50)
- ERβ decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway (2014) (49)
- Application of Metabolomics in Drug Resistant Breast Cancer Research (2015) (49)
- Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer (2011) (49)
- Analysis of tyrosine kinase mRNAs including four FGF receptor mRNAs expressed in MCF‐7 breast‐cancer cells (1992) (49)
- Reverse engineering module networks by PSO-RNN hybrid modeling (2009) (48)
- Acquired estrogen independence and antiestrogen resistance in breast cancer Estrogen receptor driven phenotypes? (1996) (48)
- Expression patterns among interferon regulatory factor-1, human X-box binding protein-1, nuclear factor kappa B, nucleophosmin, estrogen receptor-alpha and progesterone receptor proteins in breast cancer tissue microarrays. (2006) (48)
- Animal models of breast cancer: Their diversity and role in biomedical research (2005) (47)
- Orphan nuclear receptors in breast cancer pathogenesis and therapeutic response. (2010) (47)
- Systemic distribution of woodchuck hepatitis virus in the tissues of experimentally infected woodchucks. (1988) (46)
- The Role of Interferon Regulatory Factor-1 (IRF1) in Overcoming Antiestrogen Resistance in the Treatment of Breast Cancer (2011) (46)
- Functionally active estrogen receptor isoform profiles in the breast tumors of African American women are different from the profiles in breast tumors of Caucasian women (2002) (44)
- Mechanisms mediating the effects of prepubertal (n-3) polyunsaturated fatty acid diet on breast cancer risk in rats. (2005) (44)
- The biology of breast tumor progression. Acquisition of hormone independence and resistance to cytotoxic drugs. (1992) (44)
- Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data (2008) (43)
- Autophagy inhibitor 3-methyladenine potentiates apoptosis induced by dietary tocotrienols in breast cancer cells (2015) (43)
- DDN: a caBIG® analytical tool for differential network analysis (2011) (42)
- Block principal component analysis with application to gene microarray data classification (2002) (42)
- Frequent loss of heterozygosity at the interferon regulatory factor-1 gene locus in breast cancer (2010) (42)
- Identifying protein interaction subnetworks by a bagging Markov random field-based method (2012) (42)
- Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats (2017) (40)
- Alterations in behavior, steroid hormones and natural killer cell activity in male transgenic TGFα mice (1992) (39)
- Hormonal carcinogenesis in breast cancer: cellular and molecular studies of malignant progression (2004) (39)
- Radiogenomic signatures reveal multiscale intratumour heterogeneity associated with biological functions and survival in breast cancer (2020) (38)
- Monoclonal Antibody against the Ectodomain of E-Cadherin (DECMA-1) Suppresses Breast Carcinogenesis: Involvement of the HER/PI3K/Akt/mTOR and IAP Pathways (2013) (38)
- Estrogens, phytoestrogens, and breast cancer. (1996) (38)
- Optimized multilayer perceptrons for molecular classification and diagnosis using genomic data (2006) (37)
- G-DOC Plus – an integrative bioinformatics platform for precision medicine (2016) (37)
- VAV3 mediates resistance to breast cancer endocrine therapy (2014) (35)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Genome-wide identification of significant aberrations in cancer genome (2012) (33)
- Inhibition of BET proteins impairs estrogen-mediated growth and transcription in breast cancers by pausing RNA polymerase advancement (2015) (32)
- Network motif-based identification of breast cancer susceptibility genes (2008) (32)
- Hormone resistance, invasiveness, and metastatic potential in breast cancer (1993) (32)
- Autoantibodies to the Nucleolar Phosphoprotein Nucleophosmin in Breast Cancer Patients (1998) (32)
- Role of GRP78 in promoting therapeutic-resistant breast cancer. (2015) (32)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast Cancers (2015) (31)
- Discriminatory Mining of Gene Expression Microarray Data (2003) (30)
- Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer (2019) (30)
- Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model (2017) (30)
- Soluble‐E‐cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers (2014) (30)
- Overexpression of the Dominant-Negative Form of Interferon Regulatory Factor 1 in Oligodendrocytes Protects against Experimental Autoimmune Encephalomyelitis (2011) (29)
- Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes (2018) (29)
- Mathematical models of the transitions between endocrine therapy responsive and resistant states in breast cancer (2014) (29)
- Inference of Gene Regulatory Networks from Time Course Gene Expression Data Using Neural Networks and Swarm Intelligence (2006) (28)
- Modelling the effect of GRP78 on anti-oestrogen sensitivity and resistance in breast cancer (2013) (27)
- Heat shock 70 kDa protein 5/glucose-regulated protein 78 “AMP”ing up autophagy (2012) (27)
- C-7 analogues of progesterone as potent inhibitors of the P-glycoprotein efflux pump. (2002) (27)
- Modeling the estrogen receptor to growth factor receptor signaling switch in human breast cancer cells (2013) (26)
- Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate. (2015) (26)
- Targeting GRP78 and antiestrogen resistance in breast cancer. (2013) (26)
- The p 160 family coactivators regulate breast cancer cell proliferation and invasion through autocrine / paracrine activity of SDF-1 a / CXCL 12 (2005) (26)
- Knowledge-fused differential dependency network models for detecting significant rewiring in biological networks (2013) (26)
- Motif-directed network component analysis for regulatory network inference (2007) (26)
- Perinatal factors increase breast cancer risk (2004) (26)
- Gene Signaling Pathways Mediating the Opposite Effects of Prepubertal Low-Fat and High-Fat n-3 Polyunsaturated Fatty Acid Diets on Mammary Cancer Risk (2008) (26)
- Progressive Loss of Estrogen Receptor α Cofactor Recruitment in Endocrine Resistance (2007) (25)
- Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation (2016) (25)
- Differential distribution of protein phosphatase 2A in human breast carcinoma cell lines and its relation to estrogen receptor status. (1999) (24)
- Knowledge-guided multi-scale independent component analysis for biomarker identification (2008) (24)
- Gene Selection for Multiclass Prediction by Weighted Fisher Criterion (2007) (23)
- TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling (2015) (22)
- Regulation of human breast cancer by secreted growth factors. (1989) (22)
- PUGSVM: a caBIGTM analytical tool for multiclass gene selection and predictive classification (2011) (22)
- The role of preclinical animal models in breast cancer drug development (2009) (22)
- Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration (2010) (21)
- CRNET: an efficient sampling approach to infer functional regulatory networks by integrating large‐scale ChIP‐seq and time‐course RNA‐seq data (2018) (21)
- VISDA: an open-source caBIGTM analytical tool for data clustering and beyond (2007) (21)
- Gene Module Identification from Microarray Data Using Nonnegative Independent Component Analysis (2008) (21)
- Constitutive expression of the steroid sulfatase gene supports the growth of MCF-7 human breast cancer cells in vitro and in vivo. (2001) (21)
- Autoantibodies to the nuclear phosphoprotein nucleophosmin in breast cancer patients. (1998) (21)
- Cross-resistance and molecular mechanisms in antiestrogen resistance (1995) (21)
- Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance. (2015) (21)
- Progressive loss of estrogen receptor alpha cofactor recruitment in endocrine resistance. (2007) (20)
- The Proapoptotic Molecule BLID Interacts with Bcl-XL and Its Downregulation in Breast Cancer Correlates with Poor Disease-Free and Overall Survival (2010) (20)
- caBIG™ VISDA: Modeling, visualization, and discovery for cluster analysis of genomic data (2008) (20)
- Animal models of breast cancer: experimental design and their use in nutrition and psychosocial research (1997) (19)
- Matched Gene Selection and Committee Classifier for Molecular Classification of Heterogeneous Diseases (2010) (19)
- Multilevel support vector regression analysis to identify condition-specific regulatory networks (2010) (19)
- ChIP-BIT: Bayesian inference of target genes using a novel joint probabilistic model of ChIP-seq profiles (2015) (19)
- Specific binding of estradiol to rat coronary artery smooth muscle cells (1996) (18)
- Introduction and Overview: Sex Steroids in the Mammary Gland (2000) (18)
- KDDN: an open-source Cytoscape app for constructing differential dependency networks with significant rewiring (2015) (18)
- Constitutive Expression of the Steroid Sulfatase Gene Supports the Growth of MCF-7 Human Breast Cancer Cells in Vitroand in Vivo. (2001) (18)
- Endocrine therapy of human breast cancer cells: the role of secreted polypeptide growth factors. (1989) (18)
- Aromatase inhibitor plus ovarian suppression as adjuvant therapy in premenopausal women with breast cancer (2014) (17)
- Module-based breast cancer classification (2013) (17)
- LCC15-MB Cells are MDA-MB-435: A Review of Misidentified Breast and prostate cell lines (2004) (17)
- Inhibition of growth of MCF-7 MIII human breast carcinoma in nude mice by treatment with agonists or antagonists of LH-RH (1992) (17)
- EGR1 regulates cellular metabolism and survival in endocrine resistant breast cancer. (2017) (17)
- Motif-guided sparse decomposition of gene expression data for regulatory module identification (2011) (17)
- Breast cancer cell obatoclax response characterization using passivated‐electrode insulator‐based dielectrophoresis (2017) (17)
- Tissue Stem cells: Biology and Applications (2006) (16)
- The A4396G polymorphism in interferon regulatory factor 1 is frequently expressed in breast cancer cell lines. (2007) (16)
- Opposing behavioural alterations in male and female transgenic TGF alpha mice: association with tumour susceptibility. (1993) (16)
- mAPC-GibbsOS: an integrated approach for robust identification of gene regulatory networks (2013) (16)
- Vitamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells (2011) (16)
- Integration of Network Biology and Imaging to Study Cancer Phenotypes and Responses (2014) (16)
- Acquisition of an antiestrogen-resistant phenotype in breast cancer: role of cellular and molecular mechanisms. (1996) (15)
- BADGE: A novel Bayesian model for accurate abundance quantification and differential analysis of RNA-Seq data (2014) (14)
- Timing of dietary fat exposure and mammary tumorigenesis: Role of estrogen receptor and protein kinase C activity (1998) (14)
- Differentiation therapy: targeting breast cancer stem cells to reduce resistance to radiotherapy and chemotherapy (2010) (14)
- Hormone dependence of breast cancer cells and the effects of tamoxifen and estrogen:31P NMR studies (1995) (14)
- Tissue Stem Cells (2006) (14)
- AIB1 gene amplification and the instability of polyQ encoding sequence in breast cancer cell lines (2006) (14)
- The Enantioselective Binding of Mefloquine Enantiomers to P-glycoprotein Determined Using An Immobilized P-glycoprotein Liquid Chromatographic Stationary Phase (2001) (13)
- In Silico Discovery of Mitosis Regulation Networks Associated with Early Distant Metastases in Estrogen Receptor Positive Breast Cancers (2013) (13)
- Regulation of breast cancer cells by hormones and growth factors: effects on proliferation and basement membrane invasiveness. (1989) (13)
- Systems biology: perspectives on multiscale modeling in research on endocrine-related cancers. (2019) (12)
- BMRF-Net: a software tool for identification of protein interaction subnetworks by a bagging Markov random field-based method (2015) (12)
- Social isolation induces autophagy in the mouse mammary gland: link to increased mammary cancer risk. (2016) (12)
- Estrogen-Induced Apoptosis in Breast Cancers Is Phenocopied by Blocking Dephosphorylation of Eukaryotic Initiation Factor 2 Alpha (eIF2α) Protein (2019) (12)
- Identifying Early Events of Gene Expression in Breast Cancer with Systems Biology Phylogenetics (2013) (12)
- Early Life Affects the Risk of Developing Breast Cancer (1995) (12)
- Reconstruction of Transcriptional Regulatory Networks by Stability-Based Network Component Analysis (2012) (12)
- Interaction of dietary polyphenols with molecular signaling pathways of antiestrogen resistance: possible role in breast cancer recurrence (2012) (11)
- Estrogen receptor-α signaling and localization regulates autophagy and unfolded protein response activation in ER+ breast cancer. (2014) (11)
- Steroid metabolism in the hormone dependent MCF-7 human breast carcinoma cell line and its two hormone resistant subpopulations MCF-7 LCC1 and MCF-7 LCC2 (1997) (11)
- Unsupervised Deconvolution of Dynamic Imaging Reveals Intratumor Vascular Heterogeneity and Repopulation Dynamics (2013) (11)
- Inferring Network Interactions Using Recurrent Neural Networks and Swarm Intelligence (2006) (11)
- debCAM: a bioconductor R package for fully unsupervised deconvolution of complex tissues (2020) (11)
- Inhibition of estrogen receptor function promotes porcine coronary artery smooth muscle cell proliferation (1999) (11)
- Data-driven detection of subtype-specific differentially expressed genes (2019) (11)
- Evaluation of gene expression profile of keratinocytes in response to JP-8 jet fuel. (2004) (10)
- BMRF-MI: integrative identification of protein interaction network by modeling the gene dependency (2015) (10)
- Partially-independent component analysis for tissue heterogeneity correction in microarray gene expression analysis (2003) (10)
- AISAIC: a software suite for accurate identification of significant aberrations in cancers (2014) (10)
- Mechanisms of hormone and cytotoxic drug interactions in the development and treatment of breast cancer. (1990) (10)
- Robust identification of transcriptional regulatory networks using a Gibbs sampler on outlier sum statistic (2012) (10)
- Breast cancer: dietary and environmental oestrogens. (2001) (9)
- Biomarker Identification by Knowledge-Driven Multi-Level ICA and Motif Analysis (2007) (9)
- Expression of an estrogen receptor variant lacking exon 3 in derivatives of MCF-7 cells with acquired estrogen independence or tamoxifen resistance. (2004) (9)
- Knowledge-guided gene ranking by coordinative component analysis (2010) (9)
- Robust feature selection by weighted Fisher criterion for multiclass prediction in gene expression profiling (2004) (9)
- Cannibalism, cell survival, and endocrine resistance in breast cancer (2011) (9)
- Vascular Non-genomic Effects of Estrogen (1992) (9)
- Effect of estrogen withdrawal on energy-rich phosphates and prediction of estrogen dependence monitored by in vivo 31P magnetic resonance spectroscopy of four human breast cancer xenografts. (1995) (9)
- IGF-I and IGF-II expression in human breast cancer xenografts: Relationship to hormone independence (2005) (9)
- EGR1 regulates cellular metabolism and survival in endocrine resistant breast cancer (2017) (9)
- S1-8: Molecular Signaling Distinguishes Early ER Positive Breast Cancer Recurrences Despite Adjuvant Tamoxifen. (2011) (8)
- SparseIso: a novel Bayesian approach to identify alternatively spliced isoforms from RNA-seq data (2017) (8)
- Poly-ADP-Ribosylation of Estrogen Receptor-Alpha by PARP1 Mediates Antiestrogen Resistance in Human Breast Cancer Cells (2019) (8)
- Maternal obesity increases offspring’s mammary cancer recurrence and impairs tumor immune response (2020) (8)
- The Unfolded Protein Response in Cancer (2019) (8)
- The CAM software for nonnegative blind source separation in R-Java (2013) (8)
- Differential Dependency Network Analysis to Identify Topological Changes in Biological Networks (2010) (8)
- The nuclear factor K B inhibitor parthenolide restores ICI 182 , 780 ( Faslodex ; fulvestrant ) – induced apoptosis in antiestrogen-resistant breast cancer cells (2005) (8)
- When is a vesicle not just a vesicle: mitochondrial spheroids and mitochondrial autophagosomes (2014) (7)
- Growth and phenotypic characterization of porcine coronary artery smooth muscle cells (1999) (7)
- Effect of Berry Extracts and Bioactive Compounds on Fulvestrant (ICI 182,780) Sensitive and Resistant Cell Lines (2012) (7)
- A systems biology approach to discovering pathway signaling dysregulation in metastasis (2020) (7)
- Stability-Based Dimension Estimation of ICA with Application to Microarray Data Analysis (2007) (7)
- A ground truth based comparative study on clustering of gene expression data. (2008) (7)
- Linking autophagy with inflammation through IRF1 signaling in ER+ breast cancer (2016) (6)
- CyNetSVM: A Cytoscape App for Cancer Biomarker Identification Using Network Constrained Support Vector Machines (2017) (6)
- Integrative Analysis Workflow for Untargeted Metabolomics in Translational Research (2014) (6)
- Mobilisation of Ph-negative peripheral blood stem cells in CML with idarubicin and cytarabine. (1994) (6)
- PSSV: a novel pattern-based probabilistic approach for somatic structural variation identification (2017) (6)
- BACOM2.0 facilitates absolute normalization and quantification of somatic copy number alterations in heterogeneous tumor (2013) (6)
- DM-BLD: differential methylation detection using a hierarchical Bayesian model exploiting local dependency (2017) (6)
- Inhibition of Antiestrogen-Promoted Pro-Survival Autophagy and Tamoxifen Resistance in Breast Cancer through Vitamin D Receptor (2021) (6)
- Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP. (2021) (5)
- Normalization of microarray data by iterative nonlinear regression (2005) (5)
- G-CODE: enabling systems medicine through innovative informatics (2011) (5)
- Dynamical Modeling of the Interaction between Autophagy and Apoptosis in Mammalian Cells:A Systems Pharmacology Framework (2013) (5)
- Regulatory component analysis: A semi-blind extraction approach to infer gene regulatory networks with imperfect biological knowledge (2012) (5)
- Identification of Condition-specific Regulatory Modules by Multi-level Motif and mRNA Expression Analysis (2008) (5)
- Identifying intracellular signaling modules and exploring pathways associated with breast cancer recurrence (2021) (5)
- Extremely short bioavailability and fast pharmacodynamic effects of pMHC-based nanomedicines. (2021) (5)
- Introduction: Cancer Gene Networks. (2017) (5)
- SLCs contribute to endocrine resistance in breast cancer: role of SLC7A5 (LAT1) (2019) (5)
- In vitro antineoplastic activity of C7-substituted mitomycin C analogues MC-77 and MC-62 against human breast-cancer cell lines (2004) (5)
- IκB kinase-ε-mediated phosphorylation triggers IRF-1 degradation in breast cancer cells (2020) (5)
- Latent Variable and nICA Modeling of Pathway Gene Module Composite (2006) (5)
- Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α. (2014) (5)
- Dielectrophoretic properties distinguish responses to estrogen and fulvestrant in breast cancer cells (2018) (4)
- Module-based biomarker discovery in breast cancer (2010) (4)
- In vivo/in vitro Selection of Hormone-Independent Cells from the Hormone-Dependent MCF-7 Human Breast Cancer Cell Line (1989) (4)
- Human Breast-Cancer Xenografts as Models of the Human Disease (2002) (4)
- Changes in mammary caveolin-1 signaling pathways are associated with breast cancer risk in rats exposed to estradiol in utero or during prepuberty (2010) (4)
- Adverse interactions between cytotoxic drugs and hormonal agents in human breast cancer cells. (1989) (4)
- BSSV: Bayesian based somatic structural variation identification with whole genome DNA-seq data (2014) (4)
- Vitamin E succinate induces apoptosis in pancreatic cancer cells (2007) (3)
- AMPK Signaling Regulates Mitophagy and Mitochondrial ATP Production in Human Trophoblast Cell Line BeWo (2022) (3)
- BICORN: An R package for integrative inference of de novo cis-regulatory modules (2019) (3)
- swCAM: estimation of subtype-specific expressions in individual samples with unsupervised sample-wise deconvolution (2021) (3)
- Annotating breast cancer microarray samples using ontologies (2008) (3)
- Statistical Identification of Co-regulatory Gene Modules using Multiple ChIP-Seq Experiments (2014) (3)
- Roles of Spliced and Unspliced XBP1 in Breast Cancer (2019) (3)
- Integrated Identification of Disease Specific Pathways Using Multi-omics data (2019) (3)
- Human Tumours in Animal Hosts (2005) (3)
- Blockage of Lysosomal Degradation Is Detrimental to Cancer Cell Survival: Role of Autophagy Activation (2015) (3)
- Antiestrogen Resistance and the Application of Systems Biology. (2012) (3)
- Exploring Transcriptional Modules Through Integrative Gene Clustering Guided by Transcription Factor Binding Information (2008) (3)
- Abstract 835: Elevatedin uteroestrogenic environment may increase later breast cancer risk by down-regulating miRNAs (2011) (2)
- Abstract 1258: The unfolded protein response may contribute to racial disparity in endocrine responsiveness in breast cancer (2015) (2)
- Biologically inspired survival analysis based on integrating gene expression as mediator with genomic variants (2016) (2)
- A new class of small molecule estrogen receptor-alpha antagonists that overcome anti-estrogen resistance (2015) (2)
- A computer simulation of propagation through a tenuous random medium (1979) (2)
- Acquisition of estrogen independence and antiestrogen resistance in breast cancer: association with the invasive and metastatic phenotype (1995) (2)
- Abstract 907: Targeting glycolysis enzyme, PFKFB3, in endocrine therapy resistant breast cancers (2018) (2)
- The Estrogenicity of Selected Nutrients, Phytochemicals, Pesticides, and Pollutants (1999) (2)
- Gene selection in class space for molecular classification of cancer (2004) (2)
- The Estrogenicity of Selected Nutrients, Phytochemicals, Pesticides, and Pollutants: Their Potential Roles in Breast Cancer (1999) (2)
- Advancing Translational Research through Facility Design in Non-AMC Hospitals (2013) (2)
- Effects of Jaeumkanghwa-tang on tamoxifen responsiveness in preclinical ER+ breast cancer model (2019) (2)
- A feasible roadmap for unsupervised deconvolution of two-source mixed gene expressions (2013) (2)
- GIST: A Gibbs sampler to identify intracellular signal transduction pathways (2011) (2)
- Sampling-Based Subnetwork Identification from Microarray Data and Protein-Protein Interaction Network (2012) (2)
- Steroid receptors and disease: cancer, autoimmune, bone and circulatory disorders: Edited by P. J. Sheridan, K. Blum and M. C. Trachtenberg, Marcel Dekker, 1988. US$125.00 in USA and Canada (US$150.00 elsewhere) (xvi + 580 pages) ISBN 0 8247 7954 1 (1989) (2)
- The Changing Spectrum of Biomedical and Clinical Research (2015) (2)
- Modelling the effect of GRP 78 on anti-oestrogen sensitivity and resistance in breast cancer (2013) (2)
- Identification of Transcriptional Regulatory Networks by Learning the Marginal Function of Outlier Sum Statistic (2010) (2)
- Gene Selection by Weighted Fisher criterion for Multiclass Prediction (2005) (1)
- Sparse Decomposition of Gene Expression Data to Infer Transcriptional Modules Guided by Motif Information (2008) (1)
- ChIP-GSM: Inferring active transcription factor modules to predict functional regulatory elements (2021) (1)
- Abstract 1508: Integration of transcriptomic and metabolomic data reveals a central role for EGR1 in regulating survival and cellular metabolism in endocrine-resistant breast cancer (2016) (1)
- Optimizing multilayer perceptrons by discriminatory component analysis (2004) (1)
- Role of Protein Translation in Unfolded Protein Response (2019) (1)
- Abstract 2329: TMEM33 induces apoptosis via UPR signaling and autophagy in breast cancer cells (2017) (1)
- Cancer Gene Networks (2017) (1)
- Composite Gene Module Discovery using Non-negative Independent Component Analysis (2006) (1)
- Comparative Assessment and Outlook on Methods for Imputing Proteomics Data (2021) (1)
- Sample-wise unsupervised deconvolution of complex tissues (2021) (1)
- Introduction: The Unfolded Protein Response (2019) (1)
- RNA Interference Screening to Identify Proliferation Determinants in Breast Cancer Cells. (2017) (1)
- Identification of condition-specific regulatory modules through multi-level motif and mRNA expression analysis (2009) (1)
- Abstract 2070: XBP-1 promotes cell survival by activating the unfolded protein response (UPR) in antiestrogen resistance in breast cancer (2011) (1)
- RNA interference screening methods to identify proliferation determinants and mechanisms of resistance to immune attack. (2020) (1)
- Biomedical image characterization and radiogenomics (2020) (1)
- Chapter 18 – Blockage of Lysosomal Degradation is Detrimental to Cancer Cell Survival: Role of Autophagy Activation (2014) (1)
- BMRF-MI: integrative identification of protein interaction network by modeling the gene dependency (2015) (1)
- When is a vesicle not just a vesicle: mitochondrial spheroids and mitochondrial autophagosomes (2014) (1)
- GX 15-070 ( Obatoclax ) Induces Apoptosis and Inhibits Cathepsin Dand L – Mediated Autophagosomal Lysis in Antiestrogen-Resistant Breast Cancer Cells (2013) (1)
- Reconstructing transcriptional regulatory networks by probabilistic network component analysis (2013) (1)
- Inside Front Cover: Breast cancer cell obatoclax response characterization using passivated-electrode insulator-based dielectrophoresis (2017) (1)
- An approximation procedure for determining configuration factors in radiative heat transfer problems (1964) (1)
- Apoptosis, Cell Death and Breast Cancer (2008) (1)
- Blockage of Lysosomal Degradation is Detrimental to Cancer Cell Survival (2014) (1)
- Integrating multi-source biological data for transcriptional regulatory module discovery (2007) (1)
- Abstract P4-10-02: Transmembrane protein 33 (TMEM33) induces apoptosis via UPR signaling and autophagy in breast cancer cells (2017) (1)
- Abstract 2604: The Georgetown Database of Cancer (G-DOC): A web-based data sharing platform for precision medicine (2017) (1)
- A Systems Biology Approach to Identify Affected Regulatory and Signaling Circuits in Protein Interaction Networks (2009) (1)
- A T follicular helper cell origin for T regulatory type 1 cells. (2023) (1)
- Short communication The A4396G polymorphism in interferon regulatory factor 1 is frequently expressed in breast cancer cell lines (2007) (1)
- Celecoxib decreases COX-2 protein expression and increases apoptosis in ductal carcinoma in situ of the breast in vivo (2005) (1)
- Abstract P6-05-01: Endoplasmic reticulum resident protein transmembrane protein 33 (TMEM33) induces apoptosis via UPR signaling and autophagy in breast cancer cells (2015) (1)
- Data-driven robust detection of tissue/cell-specific markers (2019) (1)
- Network-Constrained Support Vector Machine for Classification (2008) (1)
- Genome-wide identification of significant aberrations in cancer genome (2012) (1)
- Abstract 4601: XBP1 regulated function of c-MYC and BCL2 in antiestrogen resistance in breast cancer (2010) (1)
- Erratum: Robust identification of transcriptional regulatory networks using a Gibbs sampler on outlier sum statistic (Bioinformatics (2012) 28:15 (1990-1997) DOI:10.1093/bioinformatics/bts296) (2014) (1)
- Genomic and network analysis to study the origin of ovarian cancer (2013) (1)
- The role of SLC7A5 (LAT1) in endocrine therapy resistant breast cancer (2019) (1)
- Determining molecular archetype composition and expression from bulk tissues with unsupervised deconvolution (2021) (1)
- A novel statistical approach to identify co-regulatory gene modules (2013) (1)
- A Markov random field-based Bayesian model to identify genes with differential methylation (2014) (1)
- DDN2.0: R and Python packages for differential dependency network analysis of biological systems (2021) (1)
- Suppressor Genes in Breast Cancer (1997) (1)
- Abstract 4595: ERK/MAPK regulation of ERRγ in Tamoxifen resistant breast cancer (2010) (1)
- Abstract B049: An integrated approach to study miRNA involvement in anti-endocrine resistance in breast cancer (2013) (1)
- The Unfolded Protein Response as an Integrator of Response to Endocrine Therapy in Estrogen Receptor Positive Breast Cancer (2019) (1)
- Human drug transporters and taxane resistance (2007) (0)
- Signaling Pathways in the Normal and Neoplastic Breast (2010) (0)
- The Role of Nutrition in Preventing and Treating Breast and Prostate Cancer Maternal and Prepubertal Diet , Mammary Development and Breast Cancer Risk 1 , 2 (2000) (0)
- ModVis: An information visualization tool for gene module discovery (2006) (0)
- Abstract 1390: In utero estrogenic exposures increase tamoxifen resistance in a new pre-clinical model of estrogen receptor positive breast cancer. (2013) (0)
- Unsupervised deconvolution of molecular heterogeneity uncovers novel signatures and glia-neuron ratio (2018) (0)
- Population remodeling in the acquisition of endocrine resistance in breast cancer (2017) (0)
- Number DAMD 1796-1-6130 TITLE : Suppressor Genes in Breast Cancer (0)
- Abstract B2-09: A systems biology approach to understanding estrogen responsiveness in breast cancer cells using the MCF7 model (2015) (0)
- Sophia Academy Roof Garden (2013) (0)
- Regulatory Factor-1 Signaling 3 Regulates the Switch between Autophagy and 4 Apoptosis to Determine Breast Cancer Cell Fate (2014) (0)
- Abstract C73: Differences in UPR signaling in ER+ breast cancer between African American and Caucasian women (2014) (0)
- Effect of Oophorectomy on Estrogen and Progesterone Receptor Concentrations in an Ovarian-Dependent and an Ovarian-Independent Human Breast Cancer Grown in Nude Mice (1989) (0)
- Abstract 904: Heterozygous ATG7 inhibition enhances endocrine therapy responsiveness through regulation of damage associated molecular patterns and priming the immune system in ER+ breast tumors (2016) (0)
- Abstract LB-254: XBP1-NFkappaB signaling promotes antiestrogen resistance in breast cancer animal model. (2013) (0)
- User Manual for BayesIso 1.0.0 demo (Matlab) (2015) (0)
- Cross phenotype normalization of microarray data. (2010) (0)
- Special FocuS : combating ReSiStance : oncology Breast cancer & antiestrogen resistance Breast cancer (2013) (0)
- Inferring Condition-Specific miRNA-Gene Modules from miRNA and mRNA Profiling Data (2008) (0)
- Resistance to endocrine therapy in breast cancer: A systems biology approach (2016) (0)
- Abstract 2443: Novel role of glucose-regulated protein 78 mediating lipid metabolism through controlling stearoyl-CoA desaturase 1 (2014) (0)
- Integrative Network Component Analysis for Regulatory Network Reconstruction (2008) (0)
- Abstract 4857: The role of autophagy in taxane resistant breast cancer models (2010) (0)
- 425 Stem cells and cancer: treatment resistance, markers and novel therapeutic targets (2010) (0)
- Abstract 580: Combined treatment of breast cancer cells with epigallocatechin gallate (EGCG) and Tamoxifen delays cell-growth in long-term culture: Implications for recurrent breast cancer (2012) (0)
- Inhibition of growth of MCF-7 MIII human breast carcinoma treatment with agonists or antagonists of LH-RH in nude mice by (0)
- BACOM2: a Java tool for detecting normal cell contamination of copy number in heterogeneous tumor (2015) (0)
- The Role of XBP-1 in Tumorigenicity (2013) (0)
- Integrating Proteotoxic Stress Response Pathways for Induction of Cell Death in Cancer Cells: Molecular Mechanisms and Therapeutic Opportunities (2015) (0)
- An Iterative Nonlinear Regression Method for Microarray Data Normalization (2007) (0)
- Abstract 1634: A novel small molecule inhibitor of IRE1alpha reverses endocrine resistance in breast cancer cells (2014) (0)
- Use of ERE and reporter gene constructs to assess putative estrogenic activity. (1999) (0)
- Abstract 2042: TOB1 promotes cell survival in estrogen-independent estrogen receptor-positive breast cancer. (2013) (0)
- Review of: Proliferation of estrogen receptor-alpha-positive mammary epithelial cells is restrained by transforming growth factor-beta1 in adult mice (2006) (0)
- Abstract B1-44: G-DOC Plus: A cloud based next-generation systems medicine platform for precision medicine (2015) (0)
- 117 Isolation and characterization of gene expression in nonmetastasizing versus metastasizing human breast cancer cells (1997) (0)
- SP153 Stem cells and breast cancer: treatment resistance, markers and novel therapeutic targets (2009) (0)
- Abstract P3-05-11: Glutamine metabolism promotes survival through the unfolded protein response in endocrine resistant breast cancer (2015) (0)
- 92nd AACR. Novel molecular targets and drugs. (2001) (0)
- Abstract 679: Glutamine metabolism in MYC-driven antiestrogen resistant breast cancer cells confers metabolic flexibility through the unfolded protein response (2014) (0)
- Mathematical modelling of molecular heterogeneity identifies novel markers and subpopulations in complex tumors (2018) (0)
- Tamoxifen Resistance in Estrogen Receptor Positive (ER+) Breast Cancer Is Driven by Estrogen Receptor Negative (ER-) Cancer Stem-Like Cells. (2009) (0)
- Abstract B1-23: Early growth response (EGR1) is a critical regulator of cellular metabolism and predicts increased responsiveness to antiestrogens in breast cancer (2015) (0)
- 128 POSTER Vitamin E succinate inhibits the in vitro growth of pancreatic cancer cells (2006) (0)
- Abstract LB-167: Prepubertal or lifetime genistein intake reduces risk of tamoxifen resistance in rats (2012) (0)
- BADGE: A novel Bayesian model for accurate abundance quantification and differential analysis of RNA-Seq data (2014) (0)
- Inhibiting glucose-regulated protein 78 modulates lipid metabolism through controlling stearoyl-CoA desaturase 1 (2014) (0)
- Abstract P3-04-12: Both spliced and unspliced XBP1 regulates breast cancer cell fate response to antiestrogen via NFkappaB signaling (2017) (0)
- Molecular mechanisms of taxane resistance (2006) (0)
- Abstract LB-148: XBP1 regulates NFkappaB signaling in antiestrogen resistant breast cancer cells (2011) (0)
- Abstract 2266: Beclin-1 regulation of autophagy in endocrine resistant breast cancer (2012) (0)
- Identifying intracellular signaling modules and exploring pathways associated with breast cancer recurrence (2021) (0)
- Abstract P4-10-01: Estrogen induced apoptosis can be mimicked by targeting unfolded protein response (2017) (0)
- Abstract 2014: An estrogen receptor - centered network for probing anti-estrogen drug resistance with siRNA screening technology (2010) (0)
- Abstract 4046: Estrogen receptor-α coordinates the unfolded protein response,autophagy, and reactive oxygen species generation to regulate breast cancer survival. (2013) (0)
- International Conference on Diet , Nutrition , and Cancer Mechanisms Mediating the Effects of Prepubertal ( n-3 ) Polyunsaturated Fatty Acid Diet on Breast Cancer Risk in Rats 1 , 2 (2005) (0)
- Machine learning and light-sheet fluorescence microscopy reveals morphometric indicators in organoids for informed anti-cancer drug discovery (2020) (0)
- Abstract 2919: XBP1 and the unfolded protein response in antiestrogen resistance in breast cancer (2010) (0)
- Abstract P2-06-14: The role of SLC7A5 (LAT1) in endocrine therapy-resistant breast cancer (2019) (0)
- Abstract P4-02-13: Social isolation promotes mammary cancer recurrence, increases IL6/JAK/STAT3 signaling and causes mitochondrial dysfunction in tamoxifen treated rats, and a traditional herbal mixture reverses all these changes (2022) (0)
- Abstract B19: Role of cell-cell communication in endocrine therapy-resistant breast cancer (2020) (0)
- C:\Documents and Settings\senthil.d\Desktop\Bioinfo-26(11)issue\btq144.dvi (2010) (0)
- Antihormone drug resistance (2013) (0)
- Abstract 3339: A role for CXCR4 signalling in the regulation of normal and malignant breast stem cell activity (2011) (0)
- XBP1, Unfolded Protein Response, and Endocrine Responsiveness (2009) (0)
- Abstract #823: NFkB inhibition restores 4-Hydroxy Tamoxifen- induced cell death and sensitivity through a caspase dependent intrinsic apoptotic cell death pathway involving Caspase 8 and Bcl-2 In antiestrogen-resistant MCF-7 breast cancer cells (2009) (0)
- Abstract 1257: In vivo inhibition of GRP78 potentiates antiestrogen therapy effectiveness in ER+ breast tumors (2015) (0)
- Binding with Acquired Resistance to Faslodex ( ICI 182 , 780 ) B , and Cyclic AMP Response Element κ Nuclear Factor-Association of Interferon Regulatory Factor-1 , Nucleophosmin , Updated (2002) (0)
- Abstract B2-41: Inference of differential dependency networks between tumor and stroma by integrated UNDO-KDDN software tool (2015) (0)
- Function of Caveolin-1 in sensitivity to taxanes in MCF-7 breast cancer cells (2006) (0)
- Targeting the UPR to Circumvent Endocrine Resistance in Breast Cancer (2015) (0)
- Abstract 196: Lifetime and adulthood dietary genistein intake have opposing effect on tamoxifen resistance in rats. (2013) (0)
- Animal models of endocrine-responsive and -unresponsive breast cancers (2002) (0)
- Abstract 2164: BLID is a novel drug-inducible apoptotic molecule: Identification of an integrative mechanism of chemosensitivity in breast cancer cells (2017) (0)
- Overcoming cancer resistance. (2015) (0)
- Development and Validation of a Method for Using Breast Core Needle Biopsies for Gene Expression Microarray Analyses 1 (2002) (0)
- IntAPT: integrated assembly of phenotype-specific transcripts from multiple RNA-seq profiles (2020) (0)
- Abstract 4311: Targeting specific regulatory subunits of protein phosphatase 1 phenocopies estrogen-induced apoptosis (2017) (0)
- Endocrine Therapy of Breast Cancer (2007) (0)
- Abstract 2179: Population remodeling in the acquisition of endocrine resistance in breast cancer (2018) (0)
- Cancer Therapy : Preclinical Monoclonal Antibody against the Ectodomain of E-Cadherin ( DECMA-1 ) Suppresses Breast Carcinogenesis : Involvement of the HER / PI 3 K / Akt / mTOR and IAP Pathways (2013) (0)
- Abstract #2378: ERR\#947;/AP1 signaling drives cholesterol production and Tamoxifen resistance in breast cancer (2009) (0)
- Abstract 1716: Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation (2015) (0)
- Abstract 4995: Glucose-regulated protein 78 regulates crosstalk between apoptosis and autophagy to determine antiestrogen responsiveness (2012) (0)
- Additional file 7: of G-DOC Plus â an integrative bioinformatics platform for precision medicine (2016) (0)
- Abstract P5-10-01: Patient advocates as partners in breast cancer research at Georgetown University Lombardi Comprehensive Cancer Center (2016) (0)
- Does the orphan nuclear receptor ERRγ link cholesterol synthesis to endocrine therapy resistance (2007) (0)
- Abstract 3638: Hypermethylation of BRCA1, and hypomethylation and overexpression of unfolded protein response (UPR) regulators EIF2AK3, IKBKB and NFkB in breast cancer may originate from elevated in utero estrogenic environment. (2013) (0)
- 79 Un“Abl”ing Anti-estrogen Therapy Resistance in Estrogen Receptor-alpha Positive Breast Cancer (2012) (0)
- Learning a highly resolved tree of phenotypes using genomic data clustering (2009) (0)
- Abstract C135: AZ’4425 is a potent, selective, and orally bio-available progesterone receptor antagonist that has shown anti-tumor activity and inhibition of cancer stem cell proliferation. (2013) (0)
- Function of Caveolin‐1 in Paclitaxel‐mediated Cytotoxicity in Breast Cancer (2007) (0)
- P4-01-12: The Unfolded Protein Response (UPR) and Pro-Survival Autophagy Contributes to Antiestrogen Resistance in Breast Cancer. (2011) (0)
- Mammary gland gene expression patterns in rats at elevated breast cancer risk due to being exposed to estradiol or leptin during pregnancy (2004) (0)
- Abstract 5023: Down-regulating interferon regulatory factor-1 by siRNA promotes endurance to fulvestrant in sensitive breast cancer cells partially via Ras/Raf/MEK/ERK pathway (2010) (0)
- G-CODE: enabling systems medicine through innovative informatics (2011) (0)
- Abstract 5671: Differential roles of caveolin-1 variants in cell death in breast cancer (2012) (0)
- Abstract 5397: MYC-driven glutamine metabolism promotes antiestrogen resistance in breast cancer. (2013) (0)
- Biomarker identification by knowledge-driven multi-scale independent component analysis (2007) (0)
- Metabolic profile of endocrine resistance (2013) (0)
- Caveolin-1 regulation of BCL-2 in paclitaxel-mediated apoptosis in breast cancer (2008) (0)
- ChIP-BIT2: a software tool to detect weak binding events using a Bayesian integration approach (2018) (0)
- Oestrogen, antioestrogen and cytotoxic drug interactions in human breast cancer cells. (1986) (0)
- CRE Activation in Antiestrogen Resistance (2005) (0)
- Author Correction: BICORN: An R package for integrative inference of de novo cis-regulatory modules (2020) (0)
- Abstract P4-08-03: Mathematical modeling of the unfolded protein response pathway in breast cancer cells (2017) (0)
- Abstract 4110: Measurement of autophagy in sensitive versus resistant breast cancer cells (2012) (0)
- Abstract A10: Unsupervised deconvolution of dynamic imaging reveals intratumor vascular heterogeneity and repopulation dynamics (2015) (0)
- Abstract 4896: The role of SLC7A5 (LAT1) in endocrine therapy-resistant breast cancer (2018) (0)
- Abstract C45: Inhibition of antiapoptotic BCL2 members facilitates interferon regulatory factor-1 (IRF1) mediated prodeath signaling in breast cancer cells (2011) (0)
- Abstract PS17-50: Nuclear expression of acetyl-CoA producing enzymes and their roles in epigenetic reprogramming in breast cancer cells (2021) (0)
- 459 Interferon Regulatory Factor-1 (IRF1) Protein Expression is Upregulated in Breast Cancer Tissue Microarrays with BRCA1 Mutations (2012) (0)
- Abstract 1667: Autophagy and unfolded protein response (UPR) signaling regulates progression of apoptosis in mammary gland involution. (2013) (0)
- Reliability Analysis of Transcriptional Regulatory Networks (2008) (0)
- Social isolation induces autophagy in the mouse mammary gland: link to increased mammary cancer risk (2017) (0)
- Glutamine metabolism and the unfolded protein response in MYC-driven breast cancer (2014) (0)
- Abstract P4-04-10: Molecular features of dormancy in ER+ breast cancers (2018) (0)
- PART I ALLY- IN DE P E N DENT C 0 M P 0 N ENT ANALYSIS FOR TISSUE HETEROGENEITY CORRECTION IN MICROARRAY GENE EXPRESSION ANALYSIS (2003) (0)
- Abstract 2783: Inhibition of prosurvival autophagy by the BH3-mimetic obatoclax sensitizes antiestrogen-resistant breast cancer cells to apoptosis (2012) (0)
- Abstract P1-18-21: Neratinib reduces HER2+/luminal B breast cancer stem cell activity and inhibits resistance by blocking efflux mechanisms (2020) (0)
- Time-dependent gene expression changes in a xenograft model of docetaxel cytotoxicity. (2009) (0)
- Inferring active cis-regulatory modules to predict functional regulatory elements (2019) (0)
- Accurate identification of significant aberrations in contaminated cancer genome (2012) (0)
- The need for new cancer therapies to target pathways involved in the development of resistance is essential to improve further the outcomes for patients. (2015) (0)
- Exploring and predicting phenotype and function in cancer biology: working in high dimensional data spaces (2007) (0)
- Abstract 1677: Inhibition of autophagy proteins ATG7 and BECN1 correlates with increased interferon regulatory factor-1 (IRF1) protein expression through STAT1 phosphorylation. (2013) (0)
- Abstract 2547: Caveolin-1 inhibits survivin and increases sensitivity to paclitaxel in breast cancer cells (2010) (0)
- Abstract 1027: Autophagy as a mediator of increased mammary cancer risk in socially isolated mice (2016) (0)
- Abstract 4600: The role of COUP transcription factors in Tamoxifen resistant breast cancer cells (2010) (0)
- Autophagy, inflammation, and breast cancer risk (2017) (0)
- The Disposition of Reduced Haloperidol and HPP,+ Metabolites of Haloperidol, is Not Influenced by P-Glycoprotein (2006) (0)
- Abstract P5-04-17: Local network topology differences between early and late recurrence in ER+ breast cancers (2019) (0)
- A CONTINUUM THEORY FOR FLUID SURFACE PHENOMENA (1970) (0)
- Mathematical Models of Death Signaling Networks (2022) (0)
- Do conditionally reprogrammed cell cultures represent the tumors they have been isolated from with high fidelity (2014) (0)
- Definition of the breakpoint fusion peptides for HLA-A3 and HLA-B8 in CML cells (2002) (0)
- 426 Identification and diagnostic performance of a small RNA within the PCA3 and BMCC1 gene locus that potentially targets mRNA (2015) (0)
- Jane Mathematical Modeling of Stem Cells : A Complexity Primer for the Stem-Cell Biologist (2014) (0)
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