Robert E. W. Hancock

Robert E. W. Hancock's AcademicInfluence.com Rankings

Biology

#1299

World Rank

#2203

Historical Rank

Microbiology

#21

World Rank

#33

Historical Rank

Neuroscience

#95

World Rank

#100

Historical Rank

biology Degrees

Download Badge

Biology

Robert E. W. Hancock's Degrees

Bachelors Microbiology University of British Columbia
PhD Microbiology University of British Columbia

Why Is Robert E. W. Hancock Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Robert Ernest William Hancock is a Canadian microbiologist and University of British Columbia Killam Professor of Microbiology and Immunology, an Associate Faculty Member of the Wellcome Trust Sanger Institute, and a Canada Research Chair in Health and Genomics.

(See a Problem?)

Robert E. W. Hancock's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen (2000) (4100)
Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances (2008) (4090)
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies (2006) (3456)
Peptide Antimicrobial Agents (2006) (2179)
Designing antimicrobial peptides: form follows function (2011) (1440)
Peptide antibiotics (1997) (1349)
Cationic peptides: a new source of antibiotics. (1998) (1309)
The role of cationic antimicrobial peptides in innate host defences. (2000) (1151)
Pseudomonas aeruginosa: new insights into pathogenesis and host defenses. (2013) (980)
Pseudomonas aeruginosa: all roads lead to resistance. (2011) (959)
Cationic peptides: effectors in innate immunity and novel antimicrobials. (2001) (940)
Antibacterial peptides for therapeutic use: obstacles and realistic outlook. (2006) (927)
InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation (2012) (916)
The role of antimicrobial peptides in animal defenses. (2000) (908)
NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis (2019) (853)
The relationship between peptide structure and antibacterial activity (2003) (844)
Cationic host defense (antimicrobial) peptides. (2006) (793)
The Human Antimicrobial Peptide LL-37 Is a Multifunctional Modulator of Innate Immune Responses1 (2002) (686)
Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli. (1999) (671)
Procedure for isolation of bacterial lipopolysaccharides from both smooth and rough Pseudomonas aeruginosa and Salmonella typhimurium strains (1983) (649)
Pseudomonas Genome Database: improved comparative analysis and population genomics capability for Pseudomonas genomes (2010) (632)
NetworkAnalyst for statistical, visual and network-based meta-analysis of gene expression data (2015) (629)
Bacterial biofilm development as a multicellular adaptation: antibiotic resistance and new therapeutic strategies. (2013) (618)
Resistance mechanisms in Pseudomonas aeruginosa and other nonfermentative gram-negative bacteria. (1998) (608)
The immunology of host defence peptides: beyond antimicrobial activity (2016) (598)
Alternatives to antibiotics-a pipeline portfolio review. (2016) (593)
Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis. (2002) (587)
Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation (2008) (568)
Role of membranes in the activities of antimicrobial cationic peptides. (2002) (558)
Adaptive and Mutational Resistance: Role of Porins and Efflux Pumps in Drug Resistance (2012) (551)
Multifunctional cationic host defence peptides and their clinical applications (2011) (545)
Modulation of the TLR-Mediated Inflammatory Response by the Endogenous Human Host Defense Peptide LL-371 (2006) (529)
Biochemical model for enhanced biological phosphorus removal (1986) (516)
Rational Design of α-Helical Antimicrobial Peptides with Enhanced Activities and Specificity/Therapeutic Index* (2005) (504)
Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and impact on treatment. (2000) (485)
Immune modulation by multifaceted cationic host defense (antimicrobial) peptides. (2013) (479)
Protein interaction data curation: the International Molecular Exchange (IMEx) consortium (2012) (477)
Alternative mechanisms of action of cationic antimicrobial peptides on bacteria (2007) (469)
Antibacterial Action of Structurally Diverse Cationic Peptides on Gram-Positive Bacteria (2000) (466)
Complete genome sequence of Pseudomonas aeruginosa PAO 1 , an opportunistic pathogen (2000) (464)
Pseudomonas aeruginosa isolates from patients with cystic fibrosis: a class of serum-sensitive, nontypable strains deficient in lipopolysaccharide O side chains (1983) (460)
Outer membrane of Pseudomonas aeruginosa: heat- 2-mercaptoethanol-modifiable proteins (1979) (459)
Mode of Action of the Antimicrobial Peptide Indolicidin* (1996) (438)
Modulating immunity as a therapy for bacterial infections (2012) (434)
Mode of action of the new antibiotic for Gram-positive pathogens daptomycin: comparison with cationic antimicrobial peptides and lipopeptides. (2006) (427)
Antimicrobial properties of lactoferrin. (2009) (425)
Cationic antimicrobial peptides activate a two‐component regulatory system, PmrA‐PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa (2003) (423)
Cationic host defence peptides: Innate immune regulatory peptides as a novel approach for treating infections (2007) (411)
Use of the fluorescent probe 1-N-phenylnaphthylamine to study the interactions of aminoglycoside antibiotics with the outer membrane of Pseudomonas aeruginosa (1984) (396)
Host defense peptides: front-line immunomodulators. (2014) (386)
InnateDB: facilitating systems-level analyses of the mammalian innate immune response (2008) (382)
Broad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response (2014) (381)
Impact of LL‐37 on anti‐infective immunity (2005) (381)
Effects of net charge and the number of positively charged residues on the biological activity of amphipathic α‐helical cationic antimicrobial peptides (2009) (376)
An anti-infective peptide that selectively modulates the innate immune response (2007) (374)
A re-evaluation of the role of host defence peptides in mammalian immunity. (2005) (374)
Interaction of Cationic Antimicrobial Peptides with Model Membranes* (2001) (371)
The bacterial outer membrane as a drug barrier. (1997) (369)
Interaction of the Cyclic Antimicrobial Cationic Peptide Bactenecin with the Outer and Cytoplasmic Membrane* (1999) (359)
Inhibition of Bacterial Biofilm Formation and Swarming Motility by a Small Synthetic Cationic Peptide (2012) (359)
The biocompatibility and biofilm resistance of implant coatings based on hydrophilic polymer brushes conjugated with antimicrobial peptides. (2011) (353)
High-throughput generation of small antibacterial peptides with improved activity (2005) (352)
Clinical development of cationic antimicrobial peptides: from natural to novel antibiotics. (2002) (352)
Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa. (2008) (340)
Swarming of Pseudomonas aeruginosa Is a Complex Adaptation Leading to Increased Production of Virulence Factors and Antibiotic Resistance (2008) (337)
Sublethal Concentrations of Pleurocidin-Derived Antimicrobial Peptides Inhibit Macromolecular Synthesis in Escherichia coli (2002) (329)
NetworkAnalyst - integrative approaches for protein–protein interaction network analysis and visual exploration (2014) (328)
Immunomodulatory Activities of Small Host Defense Peptides (2005) (319)
Comparative Genomics of Helicobacter pylori: Analysis of the Outer Membrane Protein Families (2000) (319)
Cationic antimicrobial peptides and their multifunctional role in the immune system. (2000) (313)
The value of antimicrobial peptides in the age of resistance. (2020) (312)
Interactions of Bacterial Cationic Peptide Antibiotics with Outer and Cytoplasmic Membranes ofPseudomonas aeruginosa (2000) (308)
Outer membranes of gram-negative bacteria. XIX. Isolation from Pseudomonas aeruginosa PAO1 and use in reconstitution and definition of the permeability barrier (1978) (307)
Mechanisms of action of newer antibiotics for Gram-positive pathogens. (2005) (307)
Use of artificial intelligence in the design of small peptide antibiotics effective against a broad spectrum of highly antibiotic-resistant superbugs. (2009) (306)
Regulation of virulence and antibiotic resistance by two-component regulatory systems in Pseudomonas aeruginosa. (2009) (306)
Function of pseudomonas porins in uptake and efflux. (2002) (304)
Recognition of Host Immune Activation by Pseudomonas aeruginosa (2005) (304)
Can innate immunity be enhanced to treat microbial infections? (2004) (301)
The Cationic Antimicrobial Peptide LL-37 Modulates Dendritic Cell Differentiation and Dendritic Cell-Induced T Cell Polarization1 (2004) (299)
Antimicrobial peptides on calcium phosphate-coated titanium for the prevention of implant-associated infections. (2010) (298)
Adaptive Resistance to the “Last Hope” Antibiotics Polymyxin B and Colistin in Pseudomonas aeruginosa Is Mediated by the Novel Two-Component Regulatory System ParR-ParS (2010) (292)
Multilayered coating on titanium for controlled release of antimicrobial peptides for the prevention of implant-associated infections. (2013) (288)
Cutting Edge: Cationic Antimicrobial Peptides Block the Binding of Lipopolysaccharide (LPS) to LPS Binding Protein1 (2000) (286)
PSICQUIC and PSISCORE: accessing and scoring molecular interactions (2011) (284)
Ion selectivity of gram-negative bacterial porins (1985) (284)
Structure of the bovine antimicrobial peptide indolicidin bound to dodecylphosphocholine and sodium dodecyl sulfate micelles. (2000) (283)
The roles of cathelicidin LL-37 in immune defences and novel clinical applications (2009) (274)
Immunomodulatory Properties of Defensins and Cathelicidins (2006) (268)
Host defence peptides from invertebrates--emerging antimicrobial strategies. (2006) (265)
Peptide arrays on cellulose support: SPOT synthesis, a time and cost efficient method for synthesis of large numbers of peptides in a parallel and addressable fashion (2007) (261)
The Human Cationic Peptide LL-37 Induces Activation of the Extracellular Signal-Regulated Kinase and p38 Kinase Pathways in Primary Human Monocytes1 (2004) (260)
Outer membrane permeability in Pseudomonas aeruginosa: comparison of a wild-type with an antibiotic-supersusceptible mutant (1982) (258)
Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes (2008) (257)
Antiendotoxin activity of cationic peptide antimicrobial agents (1996) (256)
Multidrug Efflux Systems Play an Important Role in the Invasiveness of Pseudomonas aeruginosa (2002) (253)
Antibiotic screening of medicinal plants of the British Columbian native peoples. (1992) (251)
Identification of novel antibacterial peptides by chemoinformatics and machine learning. (2009) (250)
Transgenic plants expressing cationic peptide chimeras exhibit broad-spectrum resistance to phytopathogens (2000) (250)
Cationic bactericidal peptides. (1995) (249)
Structural transitions as determinants of the action of the calcium-dependent antibiotic daptomycin. (2004) (244)
Compounds which increase the permeability of the Pseudomonas aeruginosa outer membrane (1984) (241)
D-enantiomeric peptides that eradicate wild-type and multidrug-resistant biofilms and protect against lethal Pseudomonas aeruginosa infections. (2015) (240)
Peptide antibiotics. (1999) (239)
Synergistic Interactions between Mammalian Antimicrobial Defense Peptides (2001) (238)
PhoP–PhoQ homologues in Pseudomonas aeruginosa regulate expression of the outer‐membrane protein OprH and polymyxin B resistance (1999) (238)
Antibiotic resistance in Pseudomonas aeruginosa biofilms: towards the development of novel anti-biofilm therapies. (2014) (237)
Antibiotic Adjuvants: Diverse Strategies for Controlling Drug-Resistant Pathogens (2014) (234)
The Commensal Streptococcus salivarius K12 Downregulates the Innate Immune Responses of Human Epithelial Cells and Promotes Host-Microbe Homeostasis (2008) (231)
Polymyxin: Alternative Mechanisms of Action and Resistance. (2016) (228)
Endotoxin Tolerance Represents a Distinctive State of Alternative Polarization (M2) in Human Mononuclear Cells (2011) (227)
Interaction of polycationic antibiotics with Pseudomonas aeruginosa lipopolysaccharide and lipid A studied by using dansyl-polymyxin (1986) (227)
Dissociation of Antimicrobial and Hemolytic Activities in Cyclic Peptide Diastereomers by Systematic Alterations in Amphipathicity* (1999) (224)
Outer membrane protein H1 of Pseudomonas aeruginosa: involvement in adaptive and mutational resistance to ethylenediaminetetraacetate, polymyxin B, and gentamicin (1980) (221)
The pmrCAB Operon Mediates Polymyxin Resistance in Acinetobacter baumannii ATCC 17978 and Clinical Isolates through Phosphoethanolamine Modification of Lipid A (2011) (220)
Host Defense Peptide LL-37, in Synergy with Inflammatory Mediator IL-1β, Augments Immune Responses by Multiple Pathways1 (2007) (216)
Involvement of the outer membrane in gentamicin and streptomycin uptake and killing in Pseudomonas aeruginosa (1981) (215)
A Broad-Spectrum Antibiofilm Peptide Enhances Antibiotic Action against Bacterial Biofilms (2014) (214)
Salt-Resistant Alpha-Helical Cationic Antimicrobial Peptides (1999) (214)
Role of Pseudomonas aeruginosa PhoP-phoQ in resistance to antimicrobial cationic peptides and aminoglycosides. (2000) (213)
Nature of the energy requirement for the irreversible adsorption of bacteriophages T1 and phi80 to Escherichia coli (1976) (212)
Collateral damage (2014) (211)
Role of porins in outer membrane permeability (1987) (210)
Peptide design for antimicrobial and immunomodulatory applications. (2013) (209)
Negative Regulation of the Pseudomonas aeruginosa Outer Membrane Porin OprD Selective for Imipenem and Basic Amino Acids (1999) (209)
Synthetic Cationic Peptide IDR-1002 Provides Protection against Bacterial Infections through Chemokine Induction and Enhanced Leukocyte Recruitment (2010) (205)
Potential of immunomodulatory host defense peptides as novel anti-infectives (2009) (203)
Screening and characterization of surface-tethered cationic peptides for antimicrobial activity. (2009) (203)
Identification of Genes Involved in Swarming Motility Using a Pseudomonas aeruginosa PAO1 Mini-Tn5-lux Mutant Library (2006) (202)
Aminoglycoside uptake and mode of action--with special reference to streptomycin and gentamicin. I. Antagonists and mutants. (1981) (202)
AMPer: a database and an automated discovery tool for antimicrobial peptides (2007) (198)
Creeping baselines and adaptive resistance to antibiotics. (2011) (197)
Reassessing the Host Defense Peptide Landscape (2019) (197)
Structure and Mechanism of Action of an Indolicidin Peptide Derivative with Improved Activity against Gram-positive Bacteria* (2001) (196)
Salmonella typhimurium Infection and Lipopolysaccharide Stimulation Induce Similar Changes in Macrophage Gene Expression1 (2000) (194)
Cerebral: a Cytoscape plugin for layout of and interaction with biological networks using subcellular localization annotation (2007) (191)
Con− Mutants: Class of Mutants in Escherichia coli K-12 Lacking a Major Cell Wall Protein and Defective in Conjugation and Adsorption of a Bacteriophage (1974) (189)
Contribution of the PhoP-PhoQ and PmrA-PmrB Two-Component Regulatory Systems to Mg2+-Induced Gene Regulation in Pseudomonas aeruginosa (2006) (185)
Construction of a mini-Tn5-luxCDABE mutant library in Pseudomonas aeruginosa PAO1: a tool for identifying differentially regulated genes. (2005) (183)
Properties of the large ion-permeable pores formed from protein F of Pseudomonas aeruginosa in lipid bilayer membranes. (1981) (182)
Antimicrobial Peptides: An Introduction. (2017) (180)
Antifungal screening of medicinal plants of British Columbian native peoples. (1994) (180)
Function and therapeutic potential of host defence peptides (2005) (180)
Therapeutic potential of host defense peptides in antibiotic-resistant infections. (2012) (179)
Antimicrobial Peptide Therapeutics for Cystic Fibrosis (2005) (179)
Structure-based design of an indolicidin peptide analogue with increased protease stability. (2003) (173)
The Cationic Antimicrobial Peptide LL-37 Modulates Dendritic Cell Differentiation and Dendritic Cell-Induced T Cell Polarization (2004) (172)
The human cationic host defense peptide LL‐37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system (2006) (171)
Sequence requirements and an optimization strategy for short antimicrobial peptides. (2006) (167)
Recombinant DNA procedures for producing small antimicrobial cationic peptides in bacteria. (1993) (167)
Improvement of outer membrane-permeabilizing and lipopolysaccharide-binding activities of an antimicrobial cationic peptide by C-terminal modification (1994) (166)
Anti-adhesive antimicrobial peptide coating prevents catheter associated infection in a mouse urinary infection model. (2017) (165)
Swarming of Pseudomonas aeruginosa Is Controlled by a Broad Spectrum of Transcriptional Regulators, Including MetR (2009) (163)
Complex Ciprofloxacin Resistome Revealed by Screening a Pseudomonas aeruginosa Mutant Library for Altered Susceptibility (2008) (163)
Aminoglycoside uptake and mode of action-with special reference to streptomycin and gentamicin. II. Effects of aminoglycosides on cells. (1981) (163)
Modulation of Structure and Antibacterial and Hemolytic Activity by Ring Size in Cyclic Gramicidin S Analogs* (1996) (163)
Permeabilization of Fungal Hyphae by the Plant Defensin NaD1 Occurs through a Cell Wall-dependent Process* (2010) (161)
Antimicrobial constituents of Rhus glabra. (1994) (161)
Intracellular Receptor for Human Host Defense Peptide LL-37 in Monocytes1 (2009) (160)
Binding of polycationic antibiotics and polyamines to lipopolysaccharides of Pseudomonas aeruginosa (1985) (157)
Interaction of Cationic Peptides with Lipoteichoic Acid and Gram-Positive Bacteria (1999) (157)
Biological Properties of Structurally Related α-Helical Cationic Antimicrobial Peptides (1999) (157)
Interaction of aminoglycosides with the outer membranes and purified lipopolysaccharide and OmpF porin of Escherichia coli (1991) (155)
Cationic antimicrobial peptides: towards clinical applications (2000) (154)
Cationic peptides: distribution and mechanisms of resistance. (2002) (154)
Ciprofloxacin Induction of a Susceptibility Determinant in Pseudomonas aeruginosa (2005) (154)
Peptide IDR‐1018: modulating the immune system and targeting bacterial biofilms to treat antibiotic‐resistant bacterial infections (2015) (153)
Synthetic antibiofilm peptides. (2016) (153)
Pseudomonas aeruginosa outer membrane permeability: isolation of a porin protein F-deficient mutant (1983) (153)
Gramicidin S is active against both gram-positive and gram-negative bacteria. (2009) (152)
Structural studies of a peptide with immune modulating and direct antimicrobial activity. (2010) (150)
Outer membrane protein P of Pseudomonas aeruginosa: regulation by phosphate deficiency and formation of small anion-specific channels in lipid bilayer membranes (1982) (150)
Interaction of macrophage cationic proteins with the outer membrane of Pseudomonas aeruginosa (1988) (150)
Pseudomonas aeruginosa Genome Database and PseudoCAP: facilitating community-based, continually updated, genome annotation (2004) (149)
Genetic Determinants Involved in the Susceptibility of Pseudomonas aeruginosa to β-Lactam Antibiotics (2010) (148)
Interaction and Cellular Localization of the Human Host Defense Peptide LL-37 with Lung Epithelial Cells (2005) (146)
INMEX—a web-based tool for integrative meta-analysis of expression data (2013) (146)
Host Defense Peptide LL-37 Selectively Reduces Proinflammatory Macrophage Responses (2011) (145)
In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design (2018) (145)
Involvement of outer membrane of Pseudomonas cepacia in aminoglycoside and polymyxin resistance (1986) (144)
Functional organization of the outer membrane of escherichia coli: phage and colicin receptors as components of iron uptake systems. (1976) (143)
Influence of proline residues on the antibacterial and synergistic activities of alpha-helical peptides. (1999) (140)
Cost-effective expression and purification of antimicrobial and host defense peptides in Escherichia coli (2010) (140)
Identification of the protein producing transmembrane diffusion pores in the outer membrane of Pseudomonas aeruginosa PA01. (1979) (140)
Critical Assessment of Methods to Quantify Biofilm Growth and Evaluate Antibiofilm Activity of Host Defence Peptides (2018) (138)
Characterization of the Polymyxin B Resistome of Pseudomonas aeruginosa (2012) (135)
Novel Genetic Determinants of Low-Level Aminoglycoside Resistance in Pseudomonas aeruginosa (2008) (134)
Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections (2009) (134)
Antibiofilm Peptides: Potential as Broad-Spectrum Agents (2016) (133)
Role of the Novel OprD Family of Porins in Nutrient Uptake in Pseudomonas aeruginosa (2006) (133)
Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens (2018) (132)
Enabling a systems biology approach to immunology: focus on innate immunity. (2009) (130)
Surface localization of Pseudomonas aeruginosa outer membrane porin protein F by using monoclonal antibodies (1983) (130)
Outer membrane proteins of Pseudomonas aeruginosa serotype strains. (1982) (130)
Monoclonal antibodies specific for Escherichia coli J5 lipopolysaccharide: cross-reaction with other gram-negative bacterial species (1984) (130)
Heterogeneity of lipopolysaccharides from Pseudomonas aeruginosa: analysis of lipopolysaccharide chain length (1988) (129)
Anti-biofilm peptides as a new weapon in antimicrobial warfare. (2016) (128)
Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast. (2002) (128)
Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium (2015) (127)
Morphology of fast-tumbling bicelles: a small angle neutron scattering and NMR study. (2001) (127)
Iron transport of Escherichia coli K-12: involvement of the colicin B receptor and of a citrate-inducible protein (1976) (127)
Antimycobacterial polyynes of Devil's Club (Oplopanax horridus), a North American native medicinal plant. (1997) (127)
Inhibition of LpxC Protects Mice from Resistant Acinetobacter baumannii by Modulating Inflammation and Enhancing Phagocytosis (2012) (125)
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen. (2005) (125)
Using microarray gene signatures to elucidate mechanisms of antibiotic action and resistance. (2005) (125)
Antibacterial surfaces based on polymer brushes: investigation on the influence of brush properties on antimicrobial peptide immobilization and antimicrobial activity. (2011) (125)
The Sensor Kinase CbrA Is a Global Regulator That Modulates Metabolism, Virulence, and Antibiotic Resistance in Pseudomonas aeruginosa (2010) (125)
Synergy of Histone-Derived Peptides of Coho Salmon with Lysozyme and Flounder Pleurocidin (2001) (124)
Pseudomonas aeruginosa outer membrane protein F: structural role and relationship to the Escherichia coli OmpA protein (1989) (124)
Improved Derivatives of Bactenecin, a Cyclic Dodecameric Antimicrobial Cationic Peptide (1999) (123)
Aminoglycoside Efflux in Pseudomonas aeruginosa: Involvement of Novel Outer Membrane Proteins (2003) (122)
Local delivery of antimicrobial peptides using self-organized TiO2 nanotube arrays for peri-implant infections. (2012) (121)
Antibiotic uptake into gram-negative bacteria (1988) (120)
New Perspectives in Biofilm Eradication. (2017) (120)
Comparison of Biophysical and Biologic Properties of α‐Helical Enantiomeric Antimicrobial Peptides (2006) (120)
Systems-Level Comparison of Host-Responses Elicited by Avian H5N1 and Seasonal H1N1 Influenza Viruses in Primary Human Macrophages (2009) (119)
Innate Defense Regulator Peptide 1018 in Wound Healing and Wound Infection (2012) (118)
Improved activity of a synthetic indolicidin analog (1997) (118)
An Endotoxin Tolerance Signature Predicts Sepsis and Organ Dysfunction at Initial Clinical Presentation (2014) (117)
Cathelicidins and functional analogues as antisepsis molecules (2007) (116)
Host defence (cationic) peptides: what is their future clinical potential? (1999) (116)
Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide (2006) (115)
The Two-Component System CprRS Senses Cationic Peptides and Triggers Adaptive Resistance in Pseudomonas aeruginosa Independently of ParRS (2012) (114)
Dynamic molecular changes during the first week of human life follow a robust developmental trajectory (2019) (114)
An α-Helical Cationic Antimicrobial Peptide Selectively Modulates Macrophage Responses to Lipopolysaccharide and Directly Alters Macrophage Gene Expression1 (2000) (113)
Antimicrobial Peptides Protect Coho Salmon fromVibrio anguillarum Infections (2000) (112)
In vitro characterization of the anticancer activity of membrane-active cationic peptides. I. Peptide-mediated cytotoxicity and peptide-enhanced cytotoxic activity of doxorubicin against wild-type and p-glycoprotein over-expressing tumor cell lines. (2000) (112)
Interaction of polyphemusin I and structural analogs with bacterial membranes, lipopolysaccharide, and lipid monolayers. (2000) (111)
Pore-forming properties of the major 53-kilodalton surface antigen from the outer sheath of Treponema denticola (1993) (111)
Peptide Antibiotics (1999) (111)
Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides. (2008) (111)
Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS‐independent activation of NF‐κB (2007) (110)
Secondary Acylation of Klebsiella pneumoniae Lipopolysaccharide Contributes to Sensitivity to Antibacterial Peptides* (2007) (109)
The Lon protease of Pseudomonas aeruginosa is induced by aminoglycosides and is involved in biofilm formation and motility. (2007) (107)
Innate Immunity Mediated by TLR5 as a Novel Antiinflammatory Target for Cystic Fibrosis Lung Disease1 (2008) (105)
The sensor kinase PhoQ mediates virulence in Pseudomonas aeruginosa. (2009) (105)
Ability of Innate Defence Regulator Peptides IDR-1002, IDR-HH2 and IDR-1018 to Protect against Mycobacterium tuberculosis Infections in Animal Models (2013) (104)
Antibacterial peptides and the outer membranes of gram-negative bacilli. (1997) (101)
Apoptosis of airway epithelial cells: human serum sensitive induction by the cathelicidin LL-37. (2006) (101)
Reevaluation, using intact cells, of the exclusion limit and role of porin OprF in Pseudomonas aeruginosa outer membrane permeability (1992) (100)
Activity of LL-37, CRAMP and antimicrobial peptide-derived compounds E2, E6 and CP26 against Mycobacterium tuberculosis. (2013) (100)
QSAR modeling and computer‐aided design of antimicrobial peptides (2008) (99)
The human cathelicidin LL-37 preferentially promotes apoptosis of infected airway epithelium. (2010) (99)
Pseudomonas aeruginosa outer membrane protein F is an adhesin in bacterial binding to lung epithelial cells in culture. (2002) (99)
Immunomodulators as adjuvants for vaccines and antimicrobial therapy (2010) (99)
Factors involved in the enhanced efficacy against gram-negative bacteria of fourth generation cephalosporins. (1992) (98)
Systems biology evaluation of immune responses induced by human host defence peptide LL-37 in mononuclear cells. (2009) (98)
The rare outer membrane protein, OmpL1, of pathogenic Leptospira species is a heat-modifiable porin (1995) (97)
Solution structure and interaction of the antimicrobial polyphemusins with lipid membranes. (2005) (97)
Deciphering the Mode of Action of the Synthetic Antimicrobial Peptide Bac8c (2011) (96)
Transgenic Potatoes Expressing a Novel Cationic Peptide are Resistant to Late Blight and Pink Rot (2004) (96)
The interaction of a recombinant cecropin/melittin hybrid peptide with the outer membrane of Pseudomonas aeruginosa (1994) (95)
Drug release and bone growth studies of antimicrobial peptide-loaded calcium phosphate coating on titanium. (2012) (95)
Human Cathelicidin Peptide LL-37 Modulates the Effects of IFN-γ on APCs1 (2009) (95)
Pathogen-induced expression of a cecropin A-melittin antimicrobial peptide gene confers antifungal resistance in transgenic tobacco. (2005) (95)
Complexities of targeting innate immunity to treat infection. (2007) (94)
An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities (2016) (94)
A conserved Aeromonas salmonicida porin provides protective immunity to rainbow trout (1995) (94)
Roles of the Carboxy-Terminal Half of Pseudomonas aeruginosa Major Outer Membrane Protein OprF in Cell Shape, Growth in Low-Osmolarity Medium, and Peptidoglycan Association (1998) (93)
Involvement of pmrAB and phoPQ in Polymyxin B Adaptation and Inducible Resistance in Non-Cystic Fibrosis Clinical Isolates of Pseudomonas aeruginosa (2009) (93)
Isolation and characterization of a family of porin proteins from Helicobacter pylori (1995) (93)
Effective Adjunctive Therapy by an Innate Defense Regulatory Peptide in a Preclinical Model of Severe Malaria (2012) (92)
Neutrophil-derived defensins as modulators of innate immune function. (2008) (92)
Chemical and chromatographic analysis of lipopolysaccharide from an antibiotic-supersusceptible mutant of Pseudomonas aeruginosa (1982) (91)
The role of specific surface loop regions in determining the function of the imipenem-specific pore protein OprD of Pseudomonas aeruginosa (1996) (91)
A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity. (2009) (91)
Effect of divalent cations on the structure of the antibiotic daptomycin (2008) (91)
ArrayPipe: a flexible processing pipeline for microarray data (2004) (89)
Expression in Escherichia coli and function of Pseudomonas aeruginosa outer membrane porin protein F (1986) (89)
The intrinsic resistome of Pseudomonas aeruginosa to β-lactams (2011) (89)
The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation. (2012) (89)
Fluorescent probes alter miscibility phase boundaries in ternary vesicles. (2007) (89)
Neutrophil Elastase Mediates Innate Host Protection against Pseudomonas aeruginosa1 (2008) (89)
Protein D1 — A glucose-inducible, pore-forming protein from the outer membrane of Pseudomonas aeruginosa (1980) (88)
Genetic definition of the substrate selectivity of outer membrane porin protein OprD of Pseudomonas aeruginosa (1993) (88)
Antibiofilm Peptides Increase the Susceptibility of Carbapenemase-Producing Klebsiella pneumoniae Clinical Isolates to β-Lactam Antibiotics (2015) (88)
Mechanism of ion transport through the anion-selective channel of the Pseudomonas aeruginosa outer membrane (1987) (87)
The Role of Sphingosine-1-Phosphate Transporter Spns2 in Immune System Function (2012) (86)
Monoclonal antibodies against Pseudomonas aeruginosa outer membrane antigens: isolation and characterization (1982) (86)
New Mouse Model for Chronic Infections by Gram-Negative Bacteria Enabling the Study of Anti-Infective Efficacy and Host-Microbe Interactions (2017) (84)
Phosphate Starvation Promotes Swarming Motility and Cytotoxicity of Pseudomonas aeruginosa (2012) (84)
Cationic amphipathic peptides KT2 and RT2 are taken up into bacterial cells and kill planktonic and biofilm bacteria. (2015) (84)
Role of porins in intrinsic antibiotic resistance of Pseudomonas cepacia (1987) (84)
Effects of single D-amino acid substitutions on disruption of beta-sheet structure and hydrophobicity in cyclic 14-residue antimicrobial peptide analogs related to gramicidin S. (2004) (83)
Optimization of Antibacterial Peptides by Genetic Algorithms and Cheminformatics (2011) (83)
Curating the innate immunity interactome (2010) (83)
Novel anti-infectives: is host defence the answer? (2008) (82)
Outer Membrane Proteins (1998) (82)
Cloning and characterization of the major outer membrane protein gene (ompH) of Pasteurella multocida X-73 (1997) (81)
Synthetic Cationic Peptide IDR-1018 Modulates Human Macrophage Differentiation (2013) (81)
High throughput screening methods for assessing antibiofilm and immunomodulatory activities of synthetic peptides (2015) (81)
Isolation of the outer membranes from Treponema pallidum and Treponema vincentii (1994) (81)
The importance of bacterial membrane composition in the structure and function of aurein 2.2 and selected variants. (2011) (80)
Lipid-specific binding of the calcium-dependent antibiotic daptomycin leads to changes in lipid polymorphism of model membranes. (2008) (80)
Rescue of Dysfunctional Autophagy Attenuates Hyperinflammatory Responses from Cystic Fibrosis Cells (2013) (80)
Role of Intracellular Proteases in the Antibiotic Resistance, Motility, and Biofilm Formation of Pseudomonas aeruginosa (2011) (80)
Determinants of recombinant production of antimicrobial cationic peptides and creation of peptide variants in bacteria. (1998) (79)
Antibacterial and antifungal polyine compounds from Glehnia littoralis ssp. leiocarpa. (1996) (78)
Broad-spectrum peptide inhibitors of aminoglycoside antibiotic resistance enzymes. (2003) (78)
Effect of membrane composition on antimicrobial peptides aurein 2.2 and 2.3 from Australian southern bell frogs. (2009) (78)
Strategies for the discovery and advancement of novel cationic antimicrobial peptides. (2010) (78)
Adaptive and Mutational Resistance: Role of Porins and Efflux Pumps in Drug Resistance (2013) (77)
Epitope mapping of the Pseudomonas aeruginosa major outer membrane porin protein OprF (1995) (77)
Manipulation of innate immunity by a bacterial secreted peptide: Lantibiotic nisin Z is selectively immunomodulatory (2013) (77)
Membrane topology and site‐specific mutagenesis of Pseudomonas aeruginosa porin OprD (1995) (77)
Antibiofilm activity of host defence peptides: complexity provides opportunities (2021) (76)
Mucin Promotes Rapid Surface Motility in Pseudomonas aeruginosa (2012) (76)
An arginine ladder in OprP mediates phosphate-specific transfer across the outer membrane (2006) (76)
ROS-deficient monocytes have aberrant gene expression that correlates with inflammatory disorders of chronic granulomatous disease. (2008) (76)
Demonstration and chemical modification of a specific phosphate binding site in the phosphate-starvation-inducible outer membrane porin protein P of Pseudomonas aeruginosa. (1986) (75)
The Lon Protease Is Essential for Full Virulence in Pseudomonas aeruginosa (2012) (75)
The innate defense regulator peptides IDR‐HH2, IDR‐1002, and IDR‐1018 modulate human neutrophil functions (2013) (75)
Using intrinsic X-ray absorption spectral differences to identify and map peptides and proteins. (2007) (74)
Treatment of Oral Multispecies Biofilms by an Anti-Biofilm Peptide (2015) (74)
Structure-activity relationships for the beta-hairpin cationic antimicrobial peptide polyphemusin I. (2004) (73)
Characterization of two surface-localized antigenic sites on porin protein F of Pseudomonas aeruginosa. (1985) (72)
Construction and characterization of Pseudomonas aeruginosa protein F-deficient mutants after in vitro and in vivo insertion mutagenesis of the cloned gene (1988) (72)
Alteration of susceptibility to EDTA, polymyxin B and gentamicin in Pseudomonas aeruginosa by divalent cation regulation of outer membrane protein H1. (1983) (72)
Immunization with PCEP microparticles containing pertussis toxoid, CpG ODN and a synthetic innate defense regulator peptide induces protective immunity against pertussis. (2011) (72)
In Vivo, In Vitro, and In Silico Characterization of Peptoids as Antimicrobial Agents (2016) (72)
Effect of BMAP-28 Antimicrobial Peptides on Leishmania major Promastigote and Amastigote Growth: Role of Leishmanolysin in Parasite Survival (2011) (71)
Effects of Hydrophobicity on the Antifungal Activity of α‐Helical Antimicrobial Peptides (2008) (71)
The novel adjuvant combination of CpG ODN, indolicidin and polyphosphazene induces potent antibody- and cell-mediated immune responses in mice. (2009) (70)
Involvement of an ATP-Dependent Protease, PA0779/AsrA, in Inducing Heat Shock in Response to Tobramycin in Pseudomonas aeruginosa (2011) (69)
Optimization of Microbial Specificity in Cyclic Peptides by Modulation of Hydrophobicity within a Defined Structural Framework* (2002) (69)
Use of luminescent bacteria for rapid screening and characterization of short cationic antimicrobial peptides synthesized on cellulose using peptide array technology (2007) (69)
LL-37 Immunomodulatory Activity during Mycobacterium tuberculosis Infection in Macrophages (2015) (69)
Evidence for two distinct mechanisms of resistance to polymyxin B in Pseudomonas aeruginosa (1984) (69)
Design of host defence peptides for antimicrobial and immunity enhancing activities. (2005) (69)
Structure and Association of Human Lactoferrin Peptides with Escherichia coli Lipopolysaccharide (2004) (69)
Evaluating Different Descriptors for Model Design of Antimicrobial Peptides with Enhanced Activity Toward P. aeruginosa (2007) (68)
Lipopolysaccharide-deficient, bacteriophage-resistant mutants of Escherichia coli K-12 (1976) (68)
Phosphate transport in Pseudomonas aeruginosa. Involvement of a periplasmic phosphate-binding protein. (1984) (68)
Quantitation and identification of antibodies to outer-membrane proteins of Pseudomonas aeruginosa in sera of patients with cystic fibrosis. (1984) (68)
Functional Genetic Variation in NFKBIA and Susceptibility to Childhood Asthma, Bronchiolitis, and Bronchopulmonary Dysplasia (2013) (67)
Enhanced immune responses and protection by vaccination with respiratory syncytial virus fusion protein formulated with CpG oligodeoxynucleotide and innate defense regulator peptide in polyphosphazene microparticles. (2012) (67)
Influence of a Putative ECF Sigma Factor on Expression of the Major Outer Membrane Protein, OprF, in Pseudomonas aeruginosa and Pseudomonas fluorescens (1999) (67)
Computer-aided Discovery of Peptides that Specifically Attack Bacterial Biofilms (2018) (67)
Antimicrobial Activity and Bacterial-Membrane Interaction of Ovine-Derived Cathelicidins (2004) (66)
Immunogenicity of Pseudomonas aeruginosa outer membrane antigens examined by crossed immunoelectrophoresis (1983) (66)
Design and Assessment of Anti-Biofilm Peptides: Steps Toward Clinical Application (2018) (66)
Sequestosome-1/p62 Is the Key Intracellular Target of Innate Defense Regulator Peptide* (2009) (66)
Short Cationic Antimicrobial Peptides Interact with ATP (2010) (66)
The Pseudomonas aeruginosa Autoinducer 3O-C12 Homoserine Lactone Provokes Hyperinflammatory Responses from Cystic Fibrosis Airway Epithelial Cells (2011) (65)
Biological properties of structurally related alpha-helical cationic antimicrobial peptides. (1999) (65)
NMR structural studies of the antibiotic lipopeptide daptomycin in DHPC micelles. (2007) (65)
Isolation and characterization of a conserved porin protein from Helicobacter pylori (1995) (65)
Atypical Activation of the Unfolded Protein Response in Cystic Fibrosis Airway Cells Contributes to p38 MAPK-Mediated Innate Immune Responses (2012) (65)
Role of Pseudomonas putida tol-oprL Gene Products in Uptake of Solutes through the Cytoplasmic Membrane (2003) (65)
The Human Host Defense Peptide LL-37 Induces Apoptosis in a Calpain- and Apoptosis-Inducing Factor–Dependent Manner Involving Bax Activity (2009) (64)
Evaluation of a Structural Model ofPseudomonas aeruginosa Outer Membrane Protein OprM, an Efflux Component Involved in Intrinsic Antibiotic Resistance (2001) (64)
Amino Acid-Mediated Induction of the Basic Amino Acid-Specific Outer Membrane Porin OprD from Pseudomonas aeruginosa (1999) (63)
Role of Pseudomonas aeruginosa outer membrane protein OprH in polymyxin and gentamicin resistance: isolation of an OprH-deficient mutant by gene replacement techniques (1992) (63)
Host Defence Peptide LL-37 Induces IL-6 Expression in Human Bronchial Epithelial Cells by Activation of the NF-κB Signaling Pathway (2008) (62)
Low concentrations of LL-37 alter IL-8 production by keratinocytes and bronchial epithelial cells in response to proinflammatory stimuli. (2009) (62)
Induction by Cationic Antimicrobial Peptides and Involvement in Intrinsic Polymyxin and Antimicrobial Peptide Resistance, Biofilm Formation, and Swarming Motility of PsrA in Pseudomonas aeruginosa (2008) (62)
Killing of Trypanosomatid Parasites by a Modified Bovine Host Defense Peptide, BMAP-18 (2009) (62)
Toward Infection-Resistant Surfaces: Achieving High Antimicrobial Peptide Potency by Modulating the Functionality of Polymer Brush and Peptide. (2015) (61)
Antibody responses in adult and neonatal BALB/c mice to immunization with novel Bordetella pertussis vaccine formulations. (2011) (61)
Characterization of the structure and membrane interaction of the antimicrobial peptides aurein 2.2 and 2.3 from Australian southern bell frogs. (2007) (60)
Bacterial Abscess Formation Is Controlled by the Stringent Stress Response and Can Be Targeted Therapeutically (2016) (59)
Anticancer activities of bovine and human lactoferricin-derived peptides. (2017) (59)
Role of Putative Loops 2 and 3 in Imipenem Passage through the Specific Porin OprD of Pseudomonas aeruginosa (2000) (59)
Signaling Pathways Mediating Chemokine Induction in Keratinocytes by Cathelicidin LL-37 and Flagellin (2012) (58)
Mechanism of Action and Limited Cross-Resistance of New Lipopeptide MX-2401 (2011) (57)
A facile method of delivery of liposomes by nebulization. (2002) (57)
Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide promotes wound healing. (2014) (57)
Designing antimicrobial peptides: form follows function (2012) (57)
Anti-mycobacterial screening of British Columbian medicinal plants (1997) (56)
Synthetic Peptides to Target Stringent Response-Controlled Virulence in a Pseudomonas aeruginosa Murine Cutaneous Infection Model (2017) (56)
Synthesis of peptide arrays using SPOT-technology and the CelluSpots-method. (2009) (56)
The major outer membrane protein OprG of Pseudomonas aeruginosa contributes to cytotoxicity and forms an anaerobically regulated, cation-selective channel. (2009) (56)
Use of specific dyes in the detection of antimicrobial compounds from crude plant extracts using a thin layer chromatography agar overlay technique (1995) (56)
MODE OF ACTION OF α‐TERTHIENYL ON ESCHERICHIA COLI: EVIDENCE FOR A PHOTODYNAMIC EFFECT ON MEMBRANES (1982) (56)
In vitro aerosol delivery and regional airway surface liquid concentration of a liposomal cationic peptide. (2001) (55)
The Liver X Receptor Agonist GW3965 Improves Recovery from Mild Repetitive Traumatic Brain Injury in Mice Partly through Apolipoprotein E (2013) (55)
Purification of glucose-inducible outer membrane protein OprB of Pseudomonas putida and reconstitution of glucose-specific pores (1991) (55)
Influence of outer membrane mutations on susceptibility of Escherichia coli to the dibasic macrolide azithromycin. (1992) (55)
A pleiotropic, posttherapy, enoxacin-resistant mutant of Pseudomonas aeruginosa (1992) (55)
INVEX—a web-based tool for integrative visualization of expression data (2013) (54)
Experimental and Theoretical Investigation of Multispecies Oral Biofilm Resistance to Chlorhexidine Treatment (2016) (54)
Diastereoisomeric analogues of gramicidin S: structure, biologicalactivity and interaction with lipid bilayers. (2000) (54)
Pseudomonas aeruginosa pili as ligands for nonopsonic phagocytosis by fibronectin-stimulated macrophages (1989) (54)
Porin activity and sequence analysis of a 31-kilodalton Treponema pallidum subsp. pallidum rare outer membrane protein (Tromp1) (1995) (54)
Membrane binding and permeation by indolicidin analogs studied by a biomimetic lipid/polydiacetylene vesicle assay (2003) (54)
Inhibition of HSV cell-to-cell spread by lactoferrin and lactoferricin. (2008) (53)
Pseudomonas aeruginosa outer membrane protein OprH: expression from the cloned gene and function in EDTA and gentamicin resistance (1991) (53)
The Amino Terminus of Pseudomonas aeruginosaOuter Membrane Protein OprF Forms Channels in Lipid Bilayer Membranes: Correlation with a Three-Dimensional Model (2000) (53)
Intrinsic antibiotic resistance of Pseudomonas aeruginosa. (1986) (53)
Identification of novel host defense peptides and the absence of α‐defensins in the bovine genome (2008) (53)
Mitogenic effects of purified outer membrane proteins from Pseudomonas aeruginosa (1980) (53)
Outer-membrane protein PhoE from Escherichia coli forms anion-selective pores in lipid-bilayer membranes. (1984) (53)
Effect of Nitroxides on Swarming Motility and Biofilm Formation, Multicellular Behaviors in Pseudomonas aeruginosa (2013) (53)
Barriers to the effective treatment of sepsis: antimicrobial agents, sepsis definitions, and host‐directed therapies (2014) (52)
Polyphosphate‐selective porin OprO of Pseudomonas aeruginosa: expression, purification and sequence (1992) (52)
Monoclonal antibodies provide protection against ocular Pseudomonas aeruginosa infection. (1988) (51)
Structure, dynamics, and antimicrobial and immune modulatory activities of human LL-23 and its single-residue variants mutated on the basis of homologous primate cathelicidins. (2012) (51)
Pseudomonas aeruginosa Outer Membrane: Peptidoglycan-Associated Proteins (1981) (51)
The Pseudomonas aeruginosa PhoP-PhoQ Two-Component Regulatory System Is Induced upon Interaction with Epithelial Cells and Controls Cytotoxicity and Inflammation (2012) (51)
Cationic antimicrobial peptide killing of African trypanosomes and Sodalis glossinidius, a bacterial symbiont of the insect vector of sleeping sickness. (2003) (51)
Outer membrane porin proteins F, P, and D1 of Pseudomonas aeruginosa and PhoE of Escherichia coli: chemical cross-linking to reveal native oligomers (1983) (51)
Secretion of alkaline phosphatase and phsopholipase C in Pseudomonas aeruginosa is specific and does not involve an increase in outer membrane permeability (1983) (50)
Evolutionary Relationships among Virulence-Associated Histidine Kinases (2001) (50)
Contrasting Transcriptional Responses of a Virulent and an Attenuated Strain of Mycobacterium tuberculosis Infecting Macrophages (2010) (49)
The therapeutic potential of cationic peptides. (1998) (49)
Bacteriophage resistance in Escherichia coli K-12: general pattern of resistance (1975) (49)
Bovine lactoferrin and lactoferricin interfere with intracellular trafficking of Herpes simplex virus-1. (2009) (49)
Enhanced binding of polycationic antibiotics to lipopolysaccharide from an aminoglycoside-supersusceptible, tolA mutant strain of Pseudomonas aeruginosa (1988) (49)
Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis (2017) (48)
Pseudomonas aeruginosa outer membrane protein OprF as an expression vector for foreign epitopes: the effects of positioning and length on the antigenicity of the epitope. (1995) (48)
A new cryptic cationic antimicrobial peptide from human apolipoprotein E with antibacterial activity and immunomodulatory effects on human cells (2016) (48)
Roles of Porin and β-Lactamase in β-Lactam Resistance of Pseudomonas aeruginosa (1988) (48)
Systems-level comparison of host responses induced by pandemic and seasonal influenza A H1N1 viruses in primary human type I-like alveolar epithelial cells in vitro (2010) (47)
Therapeutic potential of HDPs as immunomodulatory agents. (2010) (47)
The Human Cathelicidin, LL-37, Induces Granzyme-mediated Apoptosis in Regulatory T Cells (2011) (47)
Overexpression in Escherichia coli and functional analysis of a novel PPi-selective porin, oprO, from Pseudomonas aeruginosa (1992) (47)
Role of Lon, an ATP-Dependent Protease Homolog, in Resistance of Pseudomonas aeruginosa to Ciprofloxacin (2007) (47)
A novel approach to the pulmonary delivery of liposomes in dry powder form to eliminate the deleterious effects of milling. (2002) (47)
The Antimicrobial Peptide Polyphemusin Localizes to the Cytoplasm of Escherichia coli following Treatment (2006) (46)
Anti-endotoxin properties of cationic host defence peptides and proteins (2005) (46)
IRAK-4 Mutation (Q293X): Rapid Detection and Characterization of Defective Post-Transcriptional TLR/IL-1R Responses in Human Myeloid and Non-Myeloid Cells1 (2006) (46)
On the mechanism of solute uptake in Pseudomonas. (2003) (46)
Phosphate-starvation-induced outer membrane proteins of members of the families Enterobacteriaceae and Pseudomonodaceae: demonstration of immunological cross-reactivity with an antiserum specific for porin protein P of Pseudomonas aeruginosa (1986) (46)
Mastoparan is a membranolytic anti-cancer peptide that works synergistically with gemcitabine in a mouse model of mammary carcinoma. (2016) (45)
Development of multiple-antibiotic-resistant (Mar) mutants of Pseudomonas aeruginosa after serial exposure to fluoroquinolones (1995) (45)
Novel vaccine formulations against pertussis offer earlier onset of immunity and provide protection in the presence of maternal antibodies. (2013) (45)
Antimicrobial efficacy against Pseudomonas aeruginosa biofilm formation in a three-dimensional lung epithelial model and the influence of fetal bovine serum (2017) (45)
Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts (2011) (44)
A polyalanine peptide derived from polar fish with anti-infectious activities (2016) (44)
Determination of membrane immersion depth with O(2): a high-pressure (19)F NMR study. (2001) (44)
Anti-Biofilm and Immunomodulatory Activities of Peptides That Inhibit Biofilms Formed by Pathogens Isolated from Cystic Fibrosis Patients (2014) (44)
Transcription of the oprF Gene of Pseudomonas aeruginosa Is Dependent Mainly on the SigX Sigma Factor and Is Sucrose Induced (2012) (44)
The Extra-Cytoplasmic Function Sigma Factor SigX Modulates Biofilm and Virulence-Related Properties in Pseudomonas aeruginosa (2013) (44)
Metabolic Changes Associated With Adaptive Diversification in Escherichia coli (2008) (44)
A systems biology approach to nutritional immunology - focus on innate immunity. (2012) (43)
Novel method for measurement of outer membrane permeability to new beta-lactams in intact Enterobacter cloacae cells (1991) (43)
Treatment of Oral Biofilms by a D-Enantiomeric Peptide (2016) (43)
Mutator Genes Giving Rise to Decreased Antibiotic Susceptibility in Pseudomonas aeruginosa (2008) (42)
Bordetella pertussis major outer membrane porin protein forms small, anion-selective channels in lipid bilayer membranes (1986) (42)
Endosomal pH modulation by peptide-gold nanoparticle hybrids enables potent anti-inflammatory activity in phagocytic immune cells. (2016) (42)
Aggregation and Its Influence on the Immunomodulatory Activity of Synthetic Innate Defense Regulator Peptides. (2017) (41)
Bordetella pertussis Lipid A Glucosamine Modification Confers Resistance to Cationic Antimicrobial Peptides and Increases Resistance to Outer Membrane Perturbation (2014) (41)
Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities. (2016) (41)
Outer membrane protein H1 of Pseudomonas aeruginosa: purification of the protein and cloning and nucleotide sequence of the gene (1989) (40)
Identification of a penicillin-binding protein 3 homolog, PBP3x, in Pseudomonas aeruginosa: gene cloning and growth phase-dependent expression (1997) (40)
Outer membrane porin protein of Campylobacter jejuni (1986) (40)
Interaction of cationic peptides with bacterial membranes. (1997) (40)
Lipopolysaccharide-free Escherichia coli OmpF and Pseudomonas aeruginosa protein P porins are functionally active in lipid bilayer membranes (1986) (40)
Effects of growth temperature, 47-megadalton plasmid, and calcium deficiency on the outer membrane protein porin and lipopolysaccharide composition of Yersinia pestis EV76 (1983) (40)
Characterization of a proteolytically stable multifunctional host defense peptidomimetic. (2013) (40)
In Vitro Susceptibility of Burkholderia vietnamiensis to Aminoglycosides (2011) (39)
Properties of a Pseudomonas stutzeri outer membrane channel-forming protein (NosA) required for production of copper-containing N2O reductase (1989) (39)
Involvement of the Lon Protease in the SOS Response Triggered by Ciprofloxacin in Pseudomonas aeruginosa PAO1 (2012) (39)
Recombinant Treponema pallidum rare outer membrane protein 1 (Tromp1) expressed in Escherichia coli has porin activity and surface antigenic exposure (1996) (39)
Outer membrane protein K of Escherichia coli: purification and pore-forming properties in lipid bilayer membranes (1983) (39)
New insights into cathelicidin modulation of adaptive immunity (2011) (39)
Isolation of the outer membrane and characterization of the major outer membrane protein from Spirochaeta aurantia (1987) (39)
Conservation of the gene for outer membrane protein OprF in the family Pseudomonadaceae: sequence of the Pseudomonas syringae oprF gene (1991) (39)
Mechanism of uptake of deglucoteicoplanin amide derivatives across outer membranes of Escherichia coli and Pseudomonas aeruginosa (1993) (39)
Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome (2009) (38)
Strategies to link innate and adaptive immunity when designing vaccine adjuvants. (2009) (38)
Reevaluation of the factors involved in the efficacy of new beta-lactams against Enterobacter cloacae (1991) (38)
Cathelicidin Host Defense Peptides and Inflammatory Signaling: Striking a Balance (2020) (37)
Influence of preformed α-helix and α-helix induction on the activity of cationic antimicrobial peptides (2009) (37)
Characterization of OpdH, a Pseudomonas aeruginosa Porin Involved in the Uptake of Tricarboxylates (2006) (37)
Specific Association of Lectin LecB with the Surface of Pseudomonas aeruginosa: Role of Outer Membrane Protein OprF (2012) (36)
Comparison of Fatty Acid, Protein, and Serological Properties Distinguishing Outer Membranes of Pseudomonas anguilliseptica Strains from Those of Fish Pathogens and Other Pseudomonads (1983) (36)
Aurein-Derived Antimicrobial Peptides Formulated with Pegylated Phospholipid Micelles to Target Methicillin-Resistant Staphylococcus aureus Skin Infections. (2019) (36)
Purification and partial characterization of the OmpA family of proteins of Pasteurella haemolytica (1997) (36)
Characterization of, and immune responses of mice to, the purified OmpA-equivalent outer membrane protein of Pasteurella multocida serotype A:3 (Omp28). (2002) (36)
Host defense (antimicrobial) peptides (2018) (36)
Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells (2018) (35)
Mechanisms of the Innate Defense Regulator Peptide-1002 Anti-Inflammatory Activity in a Sterile Inflammation Mouse Model (2017) (35)
Analysis of the Pseudomonas aeruginosa major outer membrane protein OprF by use of truncated OprF derivatives and monoclonal antibodies (1992) (35)
Expression of an Engineered Heterologous Antimicrobial Peptide in Potato Alters Plant Development and Mitigates Normal Abiotic and Biotic Responses (2013) (35)
Purification and reconstitution in lipid bilayer membranes of an outer membrane, pore-forming protein of Aeromonas salmonicida (1983) (35)
Biomembrane interactions reveal the mechanism of action of surface-immobilized host defense IDR-1010 peptide. (2012) (35)
Antibacterial in vitro activity of fourth generation cephalosporins. (1996) (34)
An anion-selective channel from the Pseudomonas aeruginosa outer membrane (1983) (34)
Mapping and characterization of two mutations to antibiotic supersusceptibility in Pseudomonas aeruginosa. (1987) (34)
Chapter 12 Molecular organization and structural role of outer membrane macromolecules (1994) (34)
Identification of Novel Adenosine Deaminase 2 Gene Variants and Varied Clinical Phenotype in Pediatric Vasculitis (2019) (34)
Characterization of lipid A from Pseudomonas aeruginosa O-antigenic B band lipopolysaccharide by 1D and 2D NMR and mass spectral analysis. (1992) (34)
Involvement of two related porins, OprD and OpdP, in the uptake of arginine by Pseudomonas aeruginosa. (2006) (34)
A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection (2019) (33)
Visualization of Pseudomonas aeruginosa O antigens by using a protein A-dextran-colloidal gold conjugate with both immunoglobulin G and immunoglobulin M monoclonal antibodies (1987) (33)
An Immunohistological Evaluation of Pseudomonas aeruginosa Pulmonary Infection in Two Patients with Cystic Fibrosis (1987) (32)
Potentiation of ciprofloxacin action against Gram-negative bacterial biofilms by a nitroxide. (2015) (32)
Short Cationic Peptide Derived from Archaea with Dual Antibacterial Properties and Anti-Infective Potential. (2019) (32)
Delivery of liposomes in dry powder form: aerodynamic dispersion properties. (2003) (32)
Pseudomonas aeruginosa outer membrane: peptidoglycan-associated proteins (1981) (31)
Extracellular lipase from Pseudomonas aeruginosa is an amphiphilic protein. (1992) (31)
Iron transport in Escherichia coli K-12 (1977) (31)
Development of Molecularly Imprinted Polymers To Block Quorum Sensing and Inhibit Bacterial Biofilm Formation. (2018) (31)
The olsA gene mediates the synthesis of an ornithine lipid in Pseudomonas aeruginosa during growth under phosphate-limiting conditions, but is not involved in antimicrobial peptide susceptibility. (2011) (31)
The Bacterial Surface Layer Provides Protection against Antimicrobial Peptides (2012) (31)
Cloning and characterization of the Pseudomonas aeruginosa pbpB gene encoding penicillin-binding protein 3 (1995) (31)
Two Isoforms of Clp Peptidase in Pseudomonas aeruginosa Control Distinct Aspects of Cellular Physiology (2016) (31)
High-throughput detection of RNA processing in bacteria (2016) (30)
The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing* (2015) (30)
Pseudomonas aeruginosa elastase disrupts the cortisol-binding activity of corticosteroid-binding globulin. (2014) (30)
Monoclonal Antibody for an Outer Membrane Lipoprotein of the Pseudomonas fluorescens Group of the Family Pseudomonadaceae (1985) (30)
Cellulose-bound Peptide Arrays: Preparation and Applications (2007) (29)
Insertion Mutagenesis and Membrane Topology Model of the Pseudomonas aeruginosa Outer Membrane Protein OprM (2000) (29)
Modeling the Ion Selectivity of the Phosphate Specific Channel OprP. (2012) (29)
Membrane topology of the outer membrane protein OprH from Pseudomonas aeruginosa: PCR-mediated site-directed insertion and deletion mutagenesis (1996) (29)
Cathelicidin Peptide LL-37 Modulates TREM-1 Expression and Inflammatory Responses to Microbial Compounds (2011) (29)
Susceptibility to beta-lactam antibiotics of Pseudomonas aeruginosa overproducing penicillin-binding protein 3 (1997) (29)
The human cathelicidin, LL-37, induces granzyme-mediated apoptosis in cytotoxic T lymphocytes. (2011) (29)
Consensus statement understanding health and malnutrition through a systems approach: the ENOUGH program for early life (2013) (29)
Exploring the pathophysiology of post-sepsis syndrome to identify therapeutic opportunities (2020) (29)
Mechanisms of nonopsonic phagocytosis of Pseudomonas aeruginosa (1993) (29)
Importance of residue 13 and the C-terminus for the structure and activity of the antimicrobial peptide aurein 2.2. (2010) (28)
Corrigendum: Protein interaction data curation: the International Molecular Exchange (IMEx) consortium (2012) (28)
The colicin I receptor of Escherichia coli K‐12 has a role in enterochelin‐mediated iron transport (1976) (28)
Tryptic Stability of Synthetic Bactenecin Derivatives Is Determined by the Side Chain Length of Cationic Residues and the Peptide Conformation. (2016) (28)
Large-scale purification and biochemical characterization of crystallization-grade porin protein P from Pseudomonas aeruginosa. (1988) (28)
Surfing Motility: a Conserved yet Diverse Adaptation among Motile Bacteria (2018) (28)
Role of the central arginine R133 toward the ion selectivity of the phosphate specific channel OprP: effects of charge and solvation. (2013) (28)
Microtiter plate assays to assess antibiofilm activity against bacteria (2021) (27)
Helicobacter pylori: A surprisingly conserved bacterium (1998) (27)
Ciprofloxacin-nitroxide hybrids with potential for biofilm control. (2017) (27)
Comparison of immune responses and protective efficacy of intranasal prime-boost immunization regimens using adenovirus-based and CpG/HH2 adjuvanted-subunit vaccines against genital Chlamydia muridarum infection. (2012) (27)
Outer membrane protein NmpC of Escherichia coli: pore-forming properties in black lipid bilayers (1984) (27)
Functional Expression in Escherichia coli and Membrane Topology of Porin HopE, a Member of a Large Family of Conserved Proteins in Helicobacter pylori (2000) (27)
Functional and regulatory analysis of the OmpF‐like porin, OpnP, of the symbiotic bacterium Xenorhabdus nematophilus (1995) (27)
New strategies and compounds for anti-infective treatment. (2013) (27)
Outer Membrane Interaction Kinetics of New Polymyxin B Analogs in Gram-Negative Bacilli (2019) (27)
The Pseudomonas aeruginosa outer membrane permeability barrier and how to overcome it. (1985) (27)
Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5. (2019) (27)
Linker‐insertion mutagenesis of Pseudomonas aeruginosa outer membrane protein OprF (1993) (26)
Synthesis and Evaluation of Ciprofloxacin-Nitroxide Conjugates as Anti-Biofilm Agents (2016) (26)
Anion transport through the phosphate-specific OprP-channel of the Pseudomonas aeruginosa outer membrane: effects of phosphate, di- and tribasic anions and of negatively-charged lipids. (1993) (26)
Influence of preformed alpha-helix and alpha-helix induction on the activity of cationic antimicrobial peptides. (1998) (26)
A cyclic derivative of host-defence peptide IDR-1018 improves proteolytic stability, suppresses inflammation, and enhances in vivo activity. (2020) (26)
Modification of the conductance, selectivity and concentration-dependent saturation of Pseudomonas aeruginosa protein P channels by chemical acetylation. (1983) (26)
The role of fundamental research and biotechnology in finding solutions to the global problem of antibiotic resistance. (1997) (25)
Utilizing Organoid and Air-Liquid Interface Models as a Screening Method in the Development of New Host Defense Peptides (2020) (25)
PhyloBLAST: facilitating phylogenetic analysis of BLAST results (2001) (25)
Antibiotic uptake: unusual results for unusual molecules. (1992) (25)
Multidrug Adaptive Resistance of Pseudomonas aeruginosa Swarming Cells (2019) (25)
Physical mapping of 32 genetic markers on the Pseudomonas aeruginosa PAO1 chromosome. (1996) (25)
Helicobacter pylori Biofilm Formation Is Differentially Affected by Common Culture Conditions, and Proteins Play a Central Role in the Biofilm Matrix (2018) (25)
TheVibrio fischeri sapABCDF locus is required for normal growth, both in culture and in symbiosis (2002) (25)
Analysis of two gene regions involved in the expression of the imipenem-specific, outer membrane porin protein OprD of Pseudomonas aeruginosa. (1992) (24)
Antiviral indolicidin variant peptides: Evaluation for broad-spectrum disease resistance in transgenic Nicotiana tabacum (2007) (24)
An in situ Raman spectroscopy-based microfluidic "lab-on-a-chip" platform for non-destructive and continuous characterization of Pseudomonas aeruginosa biofilms. (2015) (24)
Molecular orgaruizatron and strucfural role of outer membrane macromolecules (24)
Role of gyrA mutation and loss of OprF in the multiple antibiotic resistance phenotype of Pseudomonas aeruginosa G49. (1996) (24)
Use of monoclonal antibodies to protein F of Pseudomonas aeruginosa as opsonins for phagocytosis by macrophages (1987) (24)
The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NFκB-Mediated Inflammation and Persistent Cell Cycle Disruption (2011) (24)
Role of lysines in ion selectivity of bacterial outer membrane porins. (1986) (24)
Synthetic host defense peptide IDR-1002 reduces inflammation in Pseudomonas aeruginosa lung infection (2017) (23)
Identification of a Novel Inhibition Site in Translocase MraY Based upon the Site of Interaction with Lysis Protein E from Bacteriophage ϕX174 (2014) (23)
Surface characteristics of Pseudomonas aeruginosa grown in a chamber implant model in mice and rats (1989) (23)
The complexities of antibiotic action (2007) (23)
Mammalian host defense peptides (2004) (23)
Sequencing solution: use volunteer annotators organized via Internet (2000) (23)
Antimicrobial Compounds from Alnus Rubra (1995) (23)
Synthetic Immunomodulatory Peptide IDR-1002 Enhances Monocyte Migration and Adhesion on Fibronectin (2012) (23)
Concerns regarding resistance to self-proteins. (2003) (23)
Antimicrobial Properties of MX-2401, an Expanded-Spectrum Lipopeptide Active in the Presence of Lung Surfactant (2011) (23)
Antimicrobial host defence peptide, LL-37, as a potential vaginal contraceptive. (2014) (22)
Fibronectin as an enhancer of nonopsonic phagocytosis of Pseudomonas aeruginosa by macrophages (1989) (22)
Antibacterial and antifungal compounds from Empetrum nigrum. (1995) (22)
Sequence analysis and recombinant expression of a 28-kilodalton Treponema pallidum subsp. pallidum rare outer membrane protein (Tromp2) (1997) (22)
Human organoid biofilm model for assessing antibiofilm activity of novel agents (2021) (22)
Salmonella’s Sensor for Host Defense Molecules (2005) (22)
Tuning the affinity of anion binding sites in porin channels with negatively charged residues: molecular details for OprP. (2015) (22)
Insertion mutagenesis of the Pseudomonas aeruginosa phosphate-specific porin OprP (1995) (22)
Peptide IDR-1002 Inhibits NF-κB Nuclear Translocation by Inhibition of IκBα Degradation and Activates p38/ERK1/2–MSK1-Dependent CREB Phosphorylation in Macrophages Stimulated with Lipopolysaccharide (2016) (22)
Chlorochimaphilin: a new antibiotic from Moneses uniflora. (1996) (21)
Structural Studies of a Lipid-Binding Peptide from Tunicate Hemocytes with Anti-Biofilm Activity (2016) (21)
Enhanced killing of breast cancer cells by a d-amino acid analog of the winter flounder-derived pleurocidin NRC-03. (2015) (21)
The Role of Specific Lysine Residues in the Passage of Anions through the Pseudomonas aeruginosa Porin OprP* (1996) (21)
Antimicrobial peptides: broad-spectrum antibiotics from nature. (1996) (21)
Requirement of the Pseudomonas aeruginosa CbrA Sensor Kinase for Full Virulence in a Murine Acute Lung Infection Model (2013) (21)
Influence of OprM expression on multiple antibiotic resistance in Pseudomonas aeruginosa (1997) (21)
Metabolomics Study of the Synergistic Killing of Polymyxin B in Combination with Amikacin against Polymyxin-Susceptible and -Resistant Pseudomonas aeruginosa (2019) (21)
Complete Genome Sequences of Three Pseudomonas aeruginosa Isolates with Phenotypes of Polymyxin B Adaptation and Inducible Resistance (2012) (21)
Rethinking the Antibiotic Discovery Paradigm (2015) (21)
The Outer Membranes of Pseudomonads (2004) (21)
Are we approaching the end of the antibiotic era (1998) (21)
Interconnection of post-transcriptional regulation: The RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa (2016) (20)
Role of beta-lactamase in in vivo development of ceftazidime resistance in experimental Pseudomonas aeruginosa endocarditis (1987) (20)
Broad-Spectrum Adaptive Antibiotic Resistance Associated with Pseudomonas aeruginosa Mucin-Dependent Surfing Motility (2018) (20)
A brief on bacterial biofilms (2001) (20)
Chemical modification of the anion selectivity of the PhoE porin from the Escherichia coli outer membrane. (1984) (20)
Conservation of surface epitopes in Pseudomonas aeruginosa outer membrane porin protein OprF. (1993) (20)
The Amino Terminus of Pseudomonas aeruginosa Outer Membrane Protein OprF Forms Channels in Lipid Bilayer Membranes: Correlation with a Three-Dimensional Model (2000) (19)
Outer membranes of environmental isolates of Pseudomonas aeruginosa (1988) (19)
A novel small RNA is important for biofilm formation and pathogenicity in Pseudomonas aeruginosa (2017) (19)
Identification of Synthetic and Natural Host Defense Peptides with Leishmanicidal Activity (2016) (19)
Adherence of Burkholderia cepacia to respiratory tract epithelial cells and inhibition with dextrans. (2001) (19)
Influence of Culture Conditions on Expression of the 40-Kilodalton Porin Protein of Vibrio anguillarum Serotype O2 (1998) (19)
Novel roles for two-component regulatory systems in cytotoxicity and virulence-related properties in Pseudomonas aeruginosa (2018) (19)
Linker-insertion mutagenesis of Pseudomonas aeruginosa outer membrane protein OprF. (1993) (19)
ProbeLynx: a tool for updating the association of microarray probes to genes (2004) (19)
A lipidic delivery system of a triple vaccine adjuvant enhances mucosal immunity following nasal administration in mice. (2019) (19)
Exploring relationships between mimic configuration, peptide conformation and biological activity in indolizidin-2-one amino acid analogs of gramicidin S. (2002) (18)
Comparison of the outer membrane protein and lipopolysaccharide profiles of mucoid and nonmucoid Pseudomonas aeruginosa (1990) (18)
Identification of novel targets of azithromycin activity against Pseudomonas aeruginosa grown in physiologically relevant media (2020) (18)
Roles of porin and beta-lactamase in beta-lactam resistance of Pseudomonas aeruginosa. (1988) (18)
Structural variations in nisin associated with different membrane mimicking and pH environments. (1998) (18)
Pseudomonas aeruginosa: A Persistent Pathogen in Cystic Fibrosis and Hospital-Associated Infections (2012) (17)
An Immunomodulatory Peptide Confers Protection in an Experimental Candidemia Murine Model (2017) (17)
Bone Environment Influences Irreversible Adhesion of a Methicillin-Susceptible Staphylococcus aureus Strain (2018) (17)
Analysis of two gene regions involved in the expression of the imipenem-specific, outer membrane porin protein OprD of Pseudomonas aeruginosa (1992) (17)
The Stringent Stress Response Controls Proteases and Global Regulators under Optimal Growth Conditions in Pseudomonas aeruginosa (2020) (17)
Computer-Aided Design of Antimicrobial Peptides (2010) (17)
Host Defense Peptide-Mimicking Amphiphilic β-Peptide Polymer (Bu:DM) Exhibiting Anti-Biofilm, Immunomodulatory, and in Vivo Anti-Infective Activity. (2020) (17)
Anti-endotoxin properties of cationic host defence peptides and proteins. (2005) (17)
Conditional-ready mouse embryonic stem cell derived macrophages enable the study of essential genes in macrophage function (2015) (17)
An iron-regulated LysR-type element mediates antimicrobial peptide resistance and virulence in Yersinia pseudotuberculosis. (2009) (17)
Cross-resistance between bacteriophages and colicins in Escherichia coli K-12 (1976) (17)
Antibiofilm Effect of D‐enantiomeric Peptide Alone and Combined with EDTA In Vitro (2017) (17)
The role of antimicrobial (2016) (17)
Molecular dynamics simulations informed by membrane lipidomics reveal the structure-interaction relationship of polymyxins with the lipid A-based outer membrane of Acinetobacter baumannii. (2020) (17)
Bacterial biofilms of importance to medicine and bioterrorism: proteomic techniques to identify novel vaccine components and drug targets (2003) (17)
Fluoroquinolone supersusceptibility mediated by outer membrane protein OprH overexpression in Pseudomonas aeruginosa: evidence for involvement of a nonporin pathway (1992) (16)
Alternative strategies for the study and treatment of clinical bacterial biofilms. (2017) (16)
Genome-Wide Identification of Genes Conferring Energy Related Resistance to a Synthetic Antimicrobial Peptide (Bac8c) (2013) (16)
Pseudomonas aeruginosa cytotoxin: periplasmic localization and inhibition of macrophages (1989) (16)
Systems Biology Approaches to Understanding the Human Immune System (2020) (16)
Expression of a polyphemusin variant in transgenic tobacco confers resistance against plant pathogenic bacteria, fungi and a virus (2007) (16)
MetaBridge: enabling network-based integrative analysis via direct protein interactors of metabolites (2018) (15)
Antibiotic uptake pathways across the outer membrane of Pseudomonas aeruginosa. (1987) (15)
NtrBC Regulates Invasiveness and Virulence of Pseudomonas aeruginosa During High-Density Infection (2020) (15)
Induction by innate defence regulator peptide 1018 of pro-angiogenic molecules and endothelial cell migration in a high glucose environment (2018) (15)
Whole blood transcriptional responses of very preterm infants during late-onset sepsis (2020) (15)
Antimicrobial Effect of Peptide DJK‐5 Used Alone or Mixed with EDTA on Mono‐ and Multispecies Biofilms in Dentin Canals (2018) (15)
Bacterial aggregation triggered by fibril forming tryptophan rich sequences: effects of peptide side chain and membrane phospholipids. (2020) (14)
Antibiofilm peptides: overcoming biofilm-related treatment failure (2021) (14)
Stimulation by fibronectin of macrophage-mediated phagocytosis of Pseudomonas aeruginosa (1989) (14)
Anti-infective peptide IDR-1002 augments monocyte chemotaxis towards CCR5 chemokines. (2015) (14)
G-protein-coupled receptor independent, immunomodulatory properties of chemokine CXCL9. (2010) (14)
Synthesis of bulky beta-lactams for inhibition of cell surface beta-lactamase activity. (1993) (14)
Armand-Frappier outstanding student award -- role of ATP-dependent proteases in antibiotic resistance and virulence. (2013) (14)
Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative Infections (2020) (14)
Aberrant cell migration contributes to defective airway epithelial repair in childhood wheeze. (2020) (14)
Cloning of the Pseudomonas aeruginosa outer membrane porin protein P gene: evidence for a linked region of DNA homology (1988) (14)
Exosomes, your body's answer to immune health. (2017) (14)
Differential Expression of Porins OmpP2A and OmpP2B of Haemophilus ducreyi (2004) (13)
Self‐Limiting Mussel Inspired Thin Antifouling Coating with Broad‐Spectrum Resistance to Biofilm Formation to Prevent Catheter‐Associated Infection in Mouse and Porcine Models (2021) (13)
Preparing for Life: Plasma Proteome Changes and Immune System Development During the First Week of Human Life (2020) (13)
S100A12 Serum Levels and PMN Counts Are Elevated in Childhood Systemic Vasculitides Especially Involving Proteinase 3 Specific Anti-neutrophil Cytoplasmic Antibodies (2018) (13)
An antibacterial thiophene from Balsamorhiza sagittata. (1996) (13)
Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults (2020) (13)
The importance of reporting house dust mite endotoxin abundance: impact on the lung transcriptome. (2020) (13)
Surfing motility is a complex adaptation dependent on the stringent stress response in Pseudomonas aeruginosa LESB58 (2020) (13)
Characterization of Host Responses during Pseudomonas aeruginosa Acute Infection in the Lungs and Blood and after Treatment with the Synthetic Immunomodulatory Peptide IDR-1002 (2018) (13)
Antibiotic Resistance due to Reduced Uptake (2009) (12)
Insights into the mechanism of action of two analogues of aurein 2.2. (2020) (12)
Selective anticancer activity of synthetic peptides derived from the host defence peptide tritrpticin. (2020) (12)
Contribution of swarming motility to dissemination in a Pseudomonas aeruginosa murine skin abscess infection model. (2020) (12)
Rapid Assembly of Infection-Resistant Coatings: Screening and Identification of Antimicrobial Peptides Works in Cooperation with an Antifouling Background. (2021) (12)
Colonial dissociation and susceptibility to phagocytosis of Pseudomonas aeruginosa grown in a chamber implant model in mice (1987) (12)
Liposomal Therapy Attenuates Dermonecrosis Induced by Community-Associated Methicillin-Resistant Staphylococcus aureus by Targeting α-Type Phenol-Soluble Modulins and α-Hemolysin (2018) (12)
Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens. (2022) (12)
Using anti-biofilm peptides to treat antibiotic-resistant bacterial infections. (2015) (12)
Overexpression of the Small RNA PA0805.1 in Pseudomonas aeruginosa Modulates the Expression of a Large Set of Genes and Proteins, Resulting in Altered Motility, Cytotoxicity, and Tobramycin Resistance (2020) (12)
Identification of oprG, a gene encoding a major outer membrane protein of Pseudomonas aeruginosa. (1999) (12)
Multi-Omic Data Integration Allows Baseline Immune Signatures to Predict Hepatitis B Vaccine Response in a Small Cohort (2020) (11)
Susceptibility and Resistance of Pseudomonas aeruginosa to Antimicrobial Agents (1993) (11)
The global access initiative at the University of British Columbia (UBC): Availability of UBC discoveries and technologies to the developing world. (2009) (11)
Phosphate-selective porins from the outer membranes of fluorescent Pseudomonas sp. (1987) (11)
Importance of Adaptive and Stepwise Changes in the Rise and Spread of Antimicrobial Resistance (2011) (11)
An Overview of Biological and Computational Methods for Designing Mechanism-Informed Anti-biofilm Agents (2021) (11)
Testing physiologically relevant conditions in minimal inhibitory concentration assays (2021) (11)
A broad-spectrum anti-biofilm peptide enhances antibiotic action (2014) (10)
Host Defense Peptide-Mimicking Polymers and Polymeric-Brush-Tethered Host Defense Peptides: Recent Developments, Limitations, and Potential Success (2021) (10)
Controlling biofilm formation with nitroxide functional surfaces (2019) (10)
Influence of non-natural cationic amino acids on the biological activity profile of innate defence regulator peptides. (2019) (10)
X-ray spectromicroscopy study of competitive adsorption of protein and peptide onto polystyrene-poly(methyl methacrylate) (2008) (10)
Identification of an IDR peptide formulation candidate that prevents peptide aggregation and retains immunomodulatory activity (2019) (10)
A novel mouse model of chronic suppurative otitis media and its use in preclinical antibiotic evaluation (2020) (10)
Rhinovirus Infection Drives Complex Host Airway Molecular Responses in Children With Cystic Fibrosis (2020) (10)
Fine tuning host responses in the face of infection: Emerging roles and clinical applications of host defence peptides (2010) (10)
Lipopolysaccharide Renders Transgenic Mice Expressing Human Serum Amyloid P Component Sensitive to Shiga Toxin 2 (2011) (10)
Clinical Protocol for a Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea (2020) (10)
Pore-forming ability of major outer membrane proteins from Wolinella recta ATCC 33238 (1992) (10)
Characterization and Chemical Modification of Small Anion Specific Channels formed in Lipid Bilayer Membranes by Outer Membrane Protein P or Pseudomonas aeruginosa. (1984) (9)
Application of Monoclonal Antibodies to the Study of the Surface Antigens in Pseudomonas aeruginosa (1985) (9)
Antimicrobial Peptide Delivery from Trabecular Bone Grafts (2014) (9)
Porins from Gram-Negative Bacteria in Lipid Bilayer Membranes (9)
Host Defence (bdCationic) Peptides (2012) (9)
EcDBS1R6: A novel cationic antimicrobial peptide derived from a signal peptide sequence. (2020) (9)
Use of Monoclonal Antibodies in the Study of Common Antigens of Gram-Negative Bacteria (1985) (9)
Porins of the Outer Membrane of Pseudomonas aeruginosa (2005) (9)
Antimicrobial properties of spray-dried cellulose nanocrystals and metal oxide-based nanoparticles-in-microspheres (2022) (8)
Potential of protein OprF of Pseudomonas in bivalent vaccines. (1997) (8)
Synthetic analogues of bovine bactenecin dodecapeptide reduce herpes simplex virus type 2 infectivity in mice. (2013) (8)
High-Performance Liquid Chromatography and Mass Spectrometry-Based Design of Proteolytically Stable Antimicrobial Peptides. (2017) (8)
Effect of Long-term Exposure to Peptides on Mono- and Multispecies Biofilms in Dentinal Tubules. (2019) (8)
Sensing Mg2+ contributes to the resistance of Pseudomonas aeruginosa to complement‐mediated opsonophagocytosis (2017) (7)
Dismantling the bacterial virulence program (2019) (7)
Murine Model of Sinusitis Infection for Screening Antimicrobial and Immunomodulatory Therapies (2021) (7)
Is synergy the key to treating high-density infections? (2018) (7)
A Systems Biology Approach to the Analysis of Subset-Specific Responses to Lipopolysaccharide in Dendritic Cells (2014) (7)
In Vitro and In Vivo Antibiotic Capacity of Two Host Defense Peptides (2020) (7)
Rapid microwave-based method for the preparation of antimicrobial lignin-capped silver nanoparticles active against multidrug-resistant bacteria. (2021) (7)
Multifunctional Antibiotic-Host Defense Peptide Conjugate Kills Bacteria, Eradicates Biofilms, and Modulates the Innate Immune Response. (2021) (6)
MicroReview Outer membrane proteins of Pseudomonas (1990) (6)
Host Defense Peptides: Immune Modulation and Antimicrobial Activity In Vivo (2013) (6)
Impact of Host Defense Peptides on Chronic Wounds and Infections (2018) (6)
Antibacterial and Antifungal Polyine Compounds from Glehnia littoralis ssp . (2006) (6)
Regional Dichotomy in Enteric Mucosal Immune Responses to a Persistent Mycobacterium avium ssp. paratuberculosis Infection (2020) (6)
MetaBridge: An Integrative Multi‐Omics Tool for Metabolite‐Enzyme Mapping (2020) (6)
Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity (2010) (6)
Immunotherapeutic potential of monoclonal antibodies againstPseudomonas aeruginosa protein F (1985) (6)
In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-βNspe)6-NH2 and Lau-(Lys-βNspe)6-NH2 Against PMA-Induced Acute Inflammation (2020) (6)
Determinants of the efficacy of tobramycin therapy against isogenic nonmucoid and mucoid derivatives of Pseudomonas aeruginosa PAO1 growing in peritoneal chambers in mice (1989) (6)
The effect of nitroxides on swarming motility and biofilms, multicellular behaviors in Pseudomonas aeruginosa (2013) (6)
Gene cloning and expression of the Pseudomonas aeruginosa periplasmic phosphate-binding protein (1988) (6)
Host Defense Peptides: Bridging Antimicrobial and Immunomodulatory Activities (2010) (6)
Impaired pulmonary defense against Pseudomonas aeruginosa in VEGF gene inactivated mouse lung (2013) (6)
Host Defense Peptides and Their Potential as Therapeutic Agents (2016) (6)
Different Disease Endotypes in Phenotypically Similar Vasculitides Affecting Small-to-Medium Sized Blood Vessels (2021) (5)
Unique inducible filamentous motility identified in pathogenic Bacillus cereus group species (2020) (5)
Resistance to Antibacterial Agents Acting on Cell Membranes (1984) (5)
Pseudomonas Aeruginosa: Infection and Immunity (1998) (5)
The role of the Src family kinase Lyn in the immunomodulatory activities of cathelicidin peptide LL‐37 on monocytic cells (2012) (5)
Retinoic acid elicits a coordinated expression of gut homing markers on T lymphocytes of Zambian men receiving oral Vivotif, but not Rotarix, Dukoral or OPVERO vaccines (2018) (5)
Improved activity of a synthetic indolicidin (1997) (5)
Gene Expression Profiling: Identification of Novel Pathways and Potential Biomarkers in Severe Acute Pancreatitis. (2022) (5)
a Model for Oral Multispecies Biofilm Recovery after Chlorhexidine Treatment (2016) (5)
Identification of a crocodylian β-defensin variant from Alligator mississippiensis with antimicrobial and antibiofilm activity (2021) (5)
Expression in Caulobacter crescentus of the phosphate-starvation-inducible porin OprP of Pseudomonas aeruginosa. (1991) (5)
MDA-MB-231 Breast Cancer Cells Resistant to Pleurocidin-Family Lytic Peptides Are Chemosensitive and Exhibit Reduced Tumor-Forming Capacity (2020) (5)
AB569, a nontoxic chemical tandem that kills major human pathogenic bacteria (2020) (5)
STRUCTURE OF THE BOVINE ANTIMICROBIAL PEPTIDE INDOLICIDIN BOUND TO SODIUM DODECYL SULFATE MICELLES (2000) (5)
Editorial overview: Antimicrobials in the 21st century (2001) (5)
Host Defense Peptides (2011) (5)
Immunogenicity ofPseudomonas aeruginosa OuterMembrane Antigens Examined byCrossed Immunoelectrophoresis (1983) (4)
Antimicrobial, Host Defence Peptides and Proteins (2007) (4)
An alternative approach to treating antibiotic-resistant infections. (2017) (4)
Ivacaftor or lumacaftor/ivacaftor treatment does not alter the core CF airway epithelial gene response to rhinovirus. (2020) (4)
Chapter 15 – Cathelicidins (2013) (4)
Recovery of Oral in Vitro Biofilms after Exposure to Peptides and Chlorhexidine. (2020) (4)
Enzymatically releasable polyethylene glycol - Host defense peptide conjugates with improved activity and biocompatibility. (2021) (4)
Assessing biofilm inhibition and immunomodulatory activity of small amounts of synthetic host defense peptides synthesized using SPOT-array technology (2021) (4)
Cathelicidins link the endocrine and immune systems. (2010) (4)
Increased IL-8 production in human bronchial epithelial cells after exposure to azithromycin-pretreated Pseudomonas aeruginosa in vitro. (2014) (4)
Sequence Analysis and Recombinant Expression of a 28-Kilodalton Treponema pallidum subsp . pallidum Rare Outer Membrane Protein ( Tromp 2 ) † (1997) (4)
The Pseudomonas aeruginosa whole genome sequence: A 20th anniversary celebration. (2021) (4)
Competition between Pseudomonas aeruginosa and Staphylococcus aureus is dependent on intercellular signaling and regulated by the NtrBC two-component system (2022) (4)
Characterization of immune responses and the lung transcriptome in a murine model of IL-33 challenge. (2020) (4)
Susceptibility to b-Lactam Antibiotics of Pseudomonas aeruginosa Overproducing Penicillin-Binding Protein 3 (1997) (4)
Cell-Induced T Cell Polarization Differentiation and Dendritic LL-37 Modulates Dendritic Cell The Cationic Antimicrobial Peptide (2009) (4)
The hydrophobic uptake pathway across the outer membrane of the antibiotic supersusceptible Pseudomonas aeruginosa mutant Z61 (1987) (4)
STRUCTURE OF THE BOVINE ANTIMICROBIAL PEPTIDE INDOLICIDIN BOUND TO DODECYLPHOSPHOCHOLINE MICELLES (2000) (3)
Wall-dependent Process CellPlant Defensin NaD 1 Occurs through a Permeabilization of Fungal Hyphae by the Cell Biology : (2010) (3)
New Perspectives in Bio fi lm Eradication (2017) (3)
Host Defence (Antimicrobial) Peptides and Proteins (2013) (3)
Isolation of a Tn501 insertion mutant lacking porin protein P of Pseudomonas aeruginosa (1986) (3)
Resistanceand Efflux Pumps in Drug Adaptive and Mutational Resistance: Role (2012) (3)
The use of host defense peptides in root canal therapy in rats (2020) (3)
The Small RNAs PA2952.1 and PrrH as Regulators of Virulence, Motility, and Iron Metabolism in Pseudomonas aeruginosa (2020) (3)
Canadian Bacterial Diseases Network: a new approach to university-industry relationships. (1993) (3)
Immunomodulatory Cationic Peptide Therapeutics: A New Paradigm in Infection and Immunity (2012) (3)
The ColR/S two-component system is a conserved determinant of host association across Pseudomonas species (2021) (3)
Genomic insights into the diversity, virulence and resistance of Klebsiella pneumoniae extensively drug resistant clinical isolates (2021) (3)
Monoclonal antibodies against bacterial outer membrane antigens. (1985) (3)
Membrane antigens: isolation and characterization. (1982) (2)
Pseudomonas aeruginosa : new therapeutic approaches from basic research (1985) (2)
Corrigendum: A polyalanine peptide derived from polar fish with anti-infectious activities (2016) (2)
PaIntDB: network-based omics integration and visualization using protein-protein interactions in Pseudomonas aeruginosa (2021) (2)
Host Response of Human Epidermis to Methicillin-Resistant Staphylococcus aureus Biofilm Infection and Synthetic Antibiofilm Peptide Treatment (2022) (2)
reeping baselines and adaptive resistance to antibiotics (2011) (2)
Colorimetric Biosensor Vesicles for Biotechnological Applications (2002) (2)
Antibacterial host defence peptides of bovine origin (2007) (2)
Addressing Antibiotic Failure—Beyond Genetically Encoded Antimicrobial Resistance (2022) (2)
Gut microbes shape microglia and cognitive function during malnutrition (2022) (2)
NtrBC Selectively Regulates Host-Pathogen Interactions, Virulence, and Ciprofloxacin Susceptibility of Pseudomonas aeruginosa (2021) (2)
Assessing the In Vivo Effectiveness of Cationic Lipid Nanoparticles with a Triple Adjuvant for Intranasal Vaccination against the Respiratory Pathogen Bordetella pertussis. (2022) (2)
Machine Learning-Based Single Cell and Integrative Analysis Reveals That Baseline mDC Predisposition Correlates With Hepatitis B Vaccine Antibody Response (2021) (2)
A Bovine Enteric Mycobacterium Infection Model to Analyze Parenteral Vaccine-Induced Mucosal Immunity and Accelerate Vaccine Discovery (2020) (2)
EXAGGERATED INNATE IMMUNE RESPONSES TO RHINOVIRUS INFECTION IN AIRWAY EPITHELIAL CELLS (AEC) FROM CHILDREN WITH CYSTIC FIBROSIS (2015) (2)
Structural transitions as determinants of calcium-dependent antibiotic daptomycin (2004) (2)
Predicting severity in COVID-19 disease using sepsis blood gene expression signatures (2023) (2)
A curated collection of human vaccination response signatures (2021) (2)
Machine learning-based single cell and integrative analysis reveals that baseline mDC predisposition predicts protective Hepatitis B vaccine response (2021) (2)
RNase III and RNase E Influence Posttranscriptional Regulatory Networks Involved in Virulence Factor Production, Metabolism, and Regulatory RNA Processing in Bordetella pertussis (2021) (2)
Insect Cationic Antimicrobial Peptides (2001) (2)
Immunomodulatory streptococci that inhibit CXCL8 secretion and NFκB activation are common members of the oral microbiota (2021) (2)
Erratum: The Cationic Antimicrobial Peptide LL-37 Modulates Dendritic Cell Differentiation and Dendritic Cell-Induced T Cell Polarization (Journal of Immunology (2004) 172 (1146-1156)) (2004) (2)
Peptide 1018 inhibits swarming and influences Anr-regulated gene expression downstream of the stringent stress response in Pseudomonas aeruginosa (2021) (2)
Evolutionary Relationships among Virulence-Associated (2001) (2)
2-Deoxyglucose modulates innate defence regulator peptide activity (2016) (1)
Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide promotes the healing of non-diabetic diabetic and ischemic wounds (2013) (1)
Bioinformatics: Novel Insights from Genomic Information. (2016) (1)
The effect of the length of a malarial epitope on its antigenicity and immunogenicity in an epitope presentation system using the Pseudomonas aeruginosa outer membrane protein OprF as the carrier. (1996) (1)
LpS integration into outer membrane structures (2018) (1)
Host Defense Peptides and Their Advancements in Translational Staphylococcus aureus Research (2016) (1)
Modulation of specificity in cyclic antimicrobial peptides by amphipathicity (2002) (1)
Structural Studies of An Immune Modulating and Direct Antimicrobial Peptide (2010) (1)
EXTRACELLULAR MATRIX REMODELING IN ATOPIC DERMATITIS HARNESSES THE ONSET OF AN ASTHMATIC PHENOTYPE AND IS A POTENTIAL CONTRIBUTOR TO THE ATOPIC MARCH (2022) (1)
The effect of the length of a malarial epitope on its antigenicity and immunogenicity in an epitope presentation system using the Pseudomonas aeruginosa outer membrane protein OprF as the carrier (1996) (1)
Title Systems-level comparison of host-responses elicited by avian H 5 N 1 and seasonal H 1 N 1 influenza viruses in primary human macrophages (2009) (1)
IDRs as Novel Immunomodulators (2007) (1)
Innate defence regulator peptide 1018 protects mice in the Pseudomonas aeruginosa acute lung infection model (P4045) (2013) (1)
Systems-Level Analyses of the Mammalian Innate Immune Response (2010) (1)
Dendritic Cell-Induced T Cell Polarization Modulates Dendritic Cell Differentiation and The Cationic Antimicrobial Peptide LL-37 (2003) (1)
Genetic Determinants Involved in the Susceptibility of Pseudomonas aeruginosa to (cid:1) -Lactam Antibiotics (cid:1) (2010) (1)
P92 Optimization of antibacterial peptides by genetic algorithms and QSAR (2009) (1)
Outer Membrane Protein Hi of Pseudomonas aeruginosa : Purification of the Protein and Cloning and Nucleotide Sequence of the Gene ANGUS BELL (1)
A transcriptomic analysis of the effects of macrophage polarization and endotoxin tolerance on the response to Salmonella (2022) (1)
Identifying biofilm regulators as novel targets for antimicrobial drug design (2020) (1)
SPECT/CT Imaging of 111Ag for the Preclinical Evaluation of Silver-Based Antimicrobial Nanomedicines. (2022) (1)
Dynamic molecular changes during the first week of human life follow a robust developmental trajectory (2019) (1)
Computer-aided Discovery of Peptides that Specifically Attack Bacterial Biofilms (2018) (1)
Regulationofvirulenceandantibiotic resistancebytwo-component regulatorysystems inPseudomonasaeruginosa (2009) (1)
sheath of Treponema denticola. 53-kilodalton surface antigen from the outer Pore-forming properties of the major (2013) (1)
Cathelicidins: Cationic Host Defense and Antimicrobial Peptides (2006) (1)
Ex pert Opin ion on Investigational Drugs (1998) (1)
Surviving the host: Microbial metabolic genes required for growth of Pseudomonas aeruginosa in physiologically-relevant conditions (2022) (1)
Human Mononuclear Cells State of Alternative Polarization (M2) in Endotoxin Tolerance Represents a Distinctive (2011) (0)
Contraceptive actions of Bin1b and LL-37 antimicrobial peptide : involvement of sperm sulfogalactosylglycerolipid (SGG) (2009) (0)
TheolsAgenemediates the synthesis ofanornithine lipid in Pseudomonasaeruginosaduringgrowthunderphosphate-limiting conditions , but is not involved inantimicrobial peptide susceptibility (2011) (0)
AUTHOR'S CORRECTION The Amino Terminus of Pseudomonas aeruginosa Outer Membrane Protein OprF Forms Channels in Lipid Bilayer Membranes: Correlation with a Three-Dimensional Model (2000) (0)
IDENTIFYING A NOVEL THERAPEUTIC STRATEGY FOR ASTHMA: TARGETING AIRWAY EPITHELIAL CELL RESTITUTION (2017) (0)
Monoclonal Antibody Protection Against Pseudomonas aeruginosa (1985) (0)
Interaction ofMacrophage Cationic Proteins withtheOuter MembraneofPseudomonas aeruginosa (1988) (0)
RNase III and RNase E Influence Posttranscriptional Regulatory Networks Involved in Virulence Factor Production, Metabolism, and Regulatory RNA Processing in <named-content content-type='genus-species'>Bordetella pertussis</named-content> (2021) (0)
Title Systems-level comparison of host responses induced by pandemic and seasonal influenza A H 1 N 1 viruses in primary human type Ilike alveolar epithelial cells in vitro (2010) (0)
Cationic Peptide and Swarming Motility by a Small Synthetic Inhibition of Bacterial Biofilm Formation (2012) (0)
The RoIe of Fundamentar Research and Biotechnology the Global Problem of Antibiotic Resistance (2018) (0)
Systems biology approaches to understand sepsis (2009) (0)
Laboratory Characterization of Lipopolysaccharides (LPS) (1985) (0)
Immune Responses Contributes to p38 MAPK-Mediated Innate Response in Cystic Fibrosis Airway Cells Atypical Activation of the Unfolded Protein (2012) (0)
Chapter 22 Systems-Level Analyses of the Mammalian Innate Immune Response (2010) (0)
Genome sequence of a cystic fibrosis epidemic strain of Pseudomonas aeruginosa (2008) (0)
Antimicrobials Antimicrobials in the 21 st century Editorial overview (0)
vietnamiensis to Aminoglycosides Susceptibility of Burkholderia In Vitro (2014) (0)
Hancock The therapeutic potential of cationic peptides The therapeutic potential of cationic peptides (1998) (0)
Defense Technical Information Center Compilation Part Notice ADP 014413 TITLE : Colorimetric Biosensor Vesicles for Biotechnological Applications (0)
Proton chemical shift assignments for cycloCP-11 (2008) (0)
aeruginosa Independently of ParRS Adaptive Resistance in Pseudomonas Senses Cationic Peptides and Triggers The Two-Component System CprRS (2012) (0)
The critical role of histone H 2 A-deubiquitinase Mysm 1 in hematopoiesis (2012) (0)
Cellulose-bound peptide arrays : preparation and applications 31 (2007) (0)
Human Host Defense Peptide LL-37 Inflammatory Response by the Endogenous Modulation of the TLR-Mediated (2006) (0)
Isolation and Characterization of Porins from H. pylori. (1997) (0)
Systematic design and screening of immune modulating innate defence regulator peptides (2010) (0)
Computer-Aided Design of Antimicrobial Peptides Article in Current Pharmaceutical Analysis · May 2010 (2016) (0)
O01.3 An Integrative Omics approach to understanding host cellular responses to treponema pallidum (2021) (0)
Understanding the Importance of Residue 13 and the C-terminus on the Structure and Activity of the Amphibian Antimicrobial Peptide, Aurein 2.2 (2010) (0)
Post-genomic Pseudomonas (2001) (0)
Antimicrobial Defense Synergistic Interactions between (2001) (0)
Human-induced pluripotent stem cell–derived macrophages for studying infection biology and immunology (2021) (0)
Peptides cationiques antimicrobiens (1996) (0)
CHAPTER 8 I n Model ttfembrane Studies of Porin Function (2018) (0)
Comparison of steady-state spleen DC subsets. (2014) (0)
Sucrose Induced Mainly on the SigX Sigma Factor and Is Pseudomonas aeruginosa Is Dependent Gene of oprF Transcription of the (2014) (0)
Immunomodulatory activities of cationic host defence peptides and novel therapeutic strategies. (2017) (0)
Fibrosis Lung Disease Novel Antiinflammatory Target for Cystic Innate Immunity Mediated by TLR5 as a (2013) (0)
Antimicrobial cationic peptides and methods for their identification (1996) (0)
19 THE OUTER MEMBRANES OF PSEUDOMONADS (2011) (0)
Pathways in Primary Human Monocytes Signal-Regulated Kinase and p 38 Kinase Activation of the Extracellular The Human Cationic Peptide LL-37 Induces and (2004) (0)
Antibiotic Resistance : Why Antibiotics Fail & New Ways of Overcoming Difficult Infections (2017) (0)
PV5 nmr solution structure (2005) (0)
Myeloid and Non-Myeloid Cells TLR/IL-1R Responses in Human Defective Post-Transcriptional Detection and Characterization of (2009) (0)
Novel Alligator Cathelicidin As-CATH8 Demonstrates Anti-Infective Activity against Clinically Relevant and Crocodylian Bacterial Pathogens (2022) (0)
Contents Vol. 4, 2012 (2012) (0)
Contributes to p 38 MAPK-Mediated Innate Response in Cystic Fibrosis Airway Cells Atypical Activation of the Unfolded Protein (2012) (0)
Corrigendum: Clinical Protocol for a Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea (2020) (0)
Host Defense Peptides in Fish: From the Peculiar to the Mainstream (2019) (0)
Antibiotic Resistance and Survival in the Host (2000) (0)
Peptide IDR-1018 attenuates the severity of DSS colitis by enhancing recruitment of non-inflammatory neutrophils with increased bacteriocidal activity: P-183. (2011) (0)
Rethinking the Pertussis vaccine: Formulation of lipid nanoparticles with vaccine adjuvants to achieve enhanced immunity (2020) (0)
PV5 NMR solution structure in DPC micelles (2005) (0)
Pseudomonas aeruginosa Protection against Neutrophil Elastase Mediates Innate Host (2011) (0)
Pseudomonas aeruginosa Mucin Promotes Rapid Surface Motility in 2012 (2012) (0)
Lung Epithelial Cells Human Host Defense Peptide LL-37 with Interaction and Cellular Localization of the (2004) (0)
Peptides immunomodulateurs utilisables en vue du traitement de maladies neurodégénératives évolutives (2012) (0)
The Role of the Cell Surface Components of Pseudomonas aeruginosa in Virulence (1985) (0)
Involvement oftheOuterMembraneinGentamicin and Streptomycin Uptake andKilling in Pseudomonas aeruginosa (1981) (0)
33 CFTR modulators alter innate immune responses by primary airway epithelial cells challenged with rhinovirus (2017) (0)
Groups Infection , Inflammation and Immunity ( I 3 ) (2018) (0)
Immunotherapeutic of Monodonal Antibodies Against Pseudomonas aeruginosa Protein F (1985) (0)
Myeloid and Non-Myeloid Cells TLR / IL-1 R Responses in Human Defective Post-Transcriptional Detection and Characterization of Mutation ( Q 293 X ) : RapidIRAK (2006) (0)
aeruginosaand Cytotoxicity of Pseudomonas Phosphate Starvation Promotes Swarming (2012) (0)
Synthetic innate defense regulator peptides modulate various functions of human neutrophils (2013) (0)
Immunomodulatory activity of synthetic innate defence regulators (IDRs) (134.45) (2009) (0)
Regulator Peptide Intracellular Target of Innate Defense Sequestosome-1 / p 62 Is the Key Accelerated Publication : (2009) (0)
Exploring the development of endotoxin tolerance and anti-endotoxin activity of LL-37 in mammalian cells (134.55) (2009) (0)
Cationic peptides, and methods for their preparation (1993) (0)
Chapter 9 Antibiotic Resistance Due to Reduced Uptake (2009) (0)
Peptide LL-37 Endogenous Human Host Defense Inflammatory Response by the Modulation of the TLR-Mediated (2009) (0)
Human Monocytes and p38 Kinase Pathways in Primary (2009) (0)
20 lsolation and Gharacterization of Porins from H . pylori (2018) (0)
expression . gene cloning and growth phase-dependent homolog , PBP 3 x , in Pseudomonas aeruginosa : Identification of a penicillin-binding protein 3 (1997) (0)
Design of cyclic antimicrobial peptides with low hemolytic activity (1999) (0)
Protection against Antimicrobial Peptides The Bacterial Surface Layer Provides (2012) (0)
Immunomodulatory peptides attenuate local and systemic inflammation in a murine DSS-colitis model: P-0160. (2009) (0)
OprP Pseudomonas aeruginosa Passage of Anions through the The Role of Specific Lysine Residues in the Protein Chemistry and Structure : (1996) (0)
Innate Defence Regulator Peptides as a Novel Anti-infective Strategy (94.2) (2010) (0)
The role of PI3-Kinase signalling in immunomodulation by a protective innate defence regulator peptide (135.6) (2009) (0)
Immune Multifunctional Modulator of Innate The Human Antimicrobial Peptide LL-37 Is a (2002) (0)
Disruption of the β-Sheet Structure of Cyclic Peptides by Single Amino Acid Substitution: Influence on Prokaryotic and Eukaryotic Cell Viability (2001) (0)
Cationic antimicrobial peptides and selection procedures thereof. (1996) (0)
Novel antimicrobial peptide PaDBS1R1 designed from the ribosomal protein L39E from Pyrobaculum aerophilum using bioinformatics (2016) (0)
High-throughput detection of RNA processing in bacteria (2018) (0)
of Innate Immune Responses LL-37 Is a Multifunctional Modulator The Human Antimicrobial Peptide (2009) (0)
ThemajoroutermembraneproteinOprGofPseudomonas aeruginosa contributes to cytotoxicityand formsananaerobically regulated, cation-selective channel (2009) (0)
Pseudomonas aeruginosa Virulence, and Antibiotic Resistance in Regulator That Modulates Metabolism, The Sensor Kinase CbrA Is a Global (2014) (0)
Assessing the Activity of Antimicrobial Peptides Against Common Marine Bacteria Located in Rotifer (Brachionus plicatilis) Cultures (2022) (0)
Title: Mechanistic understanding enables the rational design of salicylanilide (2020) (0)
Quantitative structure - activity relationship-based discovery of antimicrobial peptides active against multidrug-resistant bacteria. (2012) (0)
E1-4 Innate defense regulator peptides modulate neutrophil functions(English Session 1) (2012) (0)
Electrophoresis and Blotting of DNA (2013) (0)
Achtman a Preclinical Model of Severe Malaria Effective Adjunctive Therapy by an Innate Defense Regulatory Peptide in (2012) (0)
Structure of an indolicidin peptide derivative with P-->A substitution (2001) (0)
antibodies.OprF derivatives and monoclonal major outer membrane protein OprF by use of Analysis of the Pseudomonas aeruginosa (2013) (0)
Endotoxin Tolerance represents a state of alternative polarization in mononuclear cells (142.4) (2010) (0)
MINIREVIEWS RoleofPorins inOuterMembranePermeability (1987) (0)
Robert E W Hancock--boosting innate immunity to combat infection: interview by Marilynn Larkin. (2003) (0)
Isolation oftheOuterMembrane andCharacterization oftheMajor OuterMembraneProtein fromSpirochaeta aurantia (1987) (0)
Macrophage Gene Expression Induce Similar Changes in and Lipopolysaccharide Stimulation Infection Salmonella typhimurium (2009) (0)
Human Monocytes and p 38 Kinase Pathways in Primary Extracellular Signal-Regulated Kinase Induces Activation of the The Human Cationic Peptide LL-37 (2004) (0)
POLYPHEMUSIN I NMR SOLUTION STRUCTURE (2004) (0)
In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design (2018) (0)
Protein Lipopolysaccharide ( LPS ) to LPS Binding Peptides Block the Binding of Cutting Edge : Cationic Antimicrobial Buurman (1999) (0)
EcDBS1R6: A new broad-spectrum cationic antibacterial peptide derived from a signal peptide sequence (2019) (0)
Title Page / Contents / Foreword / Preface (1985) (0)
Defense Peptide LL-37 in Monocytes Intracellular Receptor for Human Host (2009) (0)
techniques.mutant by gene replacement gentamicin resistance: isolation of an membrane protein OprH in polymyxin and Role of Pseudomonas aeruginosa outer (2013) (0)
ResponsesReduces Proinflammatory Macrophage Host Defense Peptide LL-37 Selectively (2011) (0)
Structure-activity relationships in cyclic ß-sheet antibacterial peptides (2002) (0)
Susceptibili ty and Resisrance of P seud , omonas aeruginoso to Antimicrobial Agenrs (0)
The Amino Acid Sequences of BMAP-27 and BMAP-18 peptides. (2013) (0)
use of Monoclonal Antibodies in the Study of Common Antigens of Gram-Negative B acteria (0)
Determinants oftheEfficacy ofTobramycin Therapy against Isogenic Nonmucoid andMucoidDerivatives ofPseudomonas aeruginosa PAO1Growing inPeritoneal Chambers inMice (1989) (0)
Enhancing Phagocytosis by Modulating Inflammation and Acinetobacter baumannii Inhibition of LpxC Protects Mice from Resistant 2012 (2012) (0)
Human organoid biofilm model for assessing antibiofilm activity of novel agents (2021) (0)
Inducible Resistance Phenotypes of Polymyxin B Adaptation and Pseudomonas aeruginosa Isolates with Complete Genome Sequences of Three (2012) (0)
Human Myeloid and Non-Myeloid Cells Post-Transcriptional TLR / IL-1 R Responses and Characterization of Defective Mutation ( Q 293 X ) : Rapid Detection IRAK-4 Speert (2006) (0)
Antibioﬁlm Peptides Increase the Susceptibility of Carbapenemase-Producing Klebsiella pneumoniae Clinical Isolates to (cid:2) -Lactam Antibiotics (2015) (0)
Behaviors in Pseudomonas aeruginosa and Biofilm Formation , Multicellular Effect of Nitroxides on Swarming Motility (2013) (0)
from Cystic Fibrosis Cells Attenuates Hyperinflammatory Responses Rescue of Dysfunctional Autophagy (2012) (0)
Resistome of Pseudomonas aeruginosa Characterization of the Polymyxin B (2013) (0)
Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms (2023) (0)
Correction to "Multifunctional Antibiotic-Host Defense Peptide Conjugate Kills Bacteria, Eradicates Biofilms, and Modulates the Innate Immune Response". (2022) (0)
Resistance of Porins and Efflux Pumps in Drug Adaptive and Mutational Resistance : Role (2012) (0)
aeruginosa Motility and Cytotoxicity of Pseudomonas Phosphate Starvation Promotes Swarming (2012) (0)
Targeting the Pseudomonas aeruginosa Virulence Factor Phospholipase C With Engineered Liposomes (2022) (0)
Involvementoftwo related porins , OprDandOpdP , in theuptake ofarginine byPseudomonasaeruginosa (2006) (0)
Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens (2023) (0)
Formation of Pseudomonas aeruginosa Antibiotic Resistance, Motility, and Biofilm Role of Intracellular Proteases in the (2012) (0)
Impacts of PEGylation and Glycosylation on the Biological Properties of Host Defense Peptide IDR1018 (2023) (0)
Competition between Pseudomonas aeruginosa and Staphylococcus aureus is dependent on intercellular signaling and regulated by the NtrBC two-component system (2022) (0)
Role of Lon, an ATP-Dependent Protease Homolog, in Resistance of Pseudomonas aeruginosa to Ciproﬂoxacin (cid:1) (2007) (0)
p rotein interaction data curation: the i nternational m olecular exchange (ime x) consortium (2012) (0)
A NOVEL PEPTIDE FROM THE LIVER FLUKE FASCIOLA HEPATICA INHIBITS THE MIXED GRANULOCYTIC AIRWAY INFLAMMATION IN A MOUSE MODEL OF ALLERGIC ASTHMA (2017) (0)
BosR: A novel biofilm-specific regulator in Pseudomonas aeruginosa (2022) (0)
HLA-DPB1 is associated with ANCA-associated vasculitis in children. (2022) (0)
Complex Ciproﬂoxacin Resistome Revealed by Screening a Pseudomonas aeruginosa Mutant Library for Altered Susceptibility (cid:1) (2008) (0)
This information is current as on APCs γ Modulates the Effects of IFN-Human Cathelicidin Peptide LL-37 and (2009) (0)
Immune Responses by Multiple Pathways , Augments β Inflammatory Mediator IL-1 Host Defense Peptide LL-37 , in Synergy with (2007) (0)
Structure of a cyclic indolicidin peptide derivative with higher charge (2003) (0)
Focus Session 13: Functional Genomics (2014) (0)
Understanding the Anti-Inflammatory Properties of Low-Dose Intranasal Simvastatin in a Murine Model of Allergic Asthma (0)
Cross resistance amongst coliphages / Robert E.W. Hancock (1974) (0)
DysplasiaBronchiolitis, and Bronchopulmonary Susceptibility to Childhood Asthma, and NFKBIA Functional Genetic Variation in (2013) (0)
The host defence peptide LL-37 is a potent inducer of chemokine production by primary human monocytes (2005) (0)
The human cathelicidin, LL-37, kills through activation of the mitochondrial-associated pathway of apoptosis in a caspase-independent manner (2007) (0)
Immunity to virus infection (excluding retroviruses) (PP-025) (2010) (0)
Ivacaftor or Lumacaftor/Ivacaftor Treatment Does Not Alter the Core CF Airway Epithelial Gene Response to Rhinovirus (2020) (0)
IDRs as Novel Immunomodulators (B208) (2007) (0)
Involvement ofOuterMembraneofPseudomonas cepacia in Aminoglycoside andPolymyxin Resistance (1986) (0)
TITLE: EXTRACELLULAR MATRIX REMODELING IN ATOPIC DERMATITIS HAR- 1 NESSES THE ONSET OF AN ASTHMATIC PHENOTYPE AND IS A POTENTIAL CON- (2022) (0)
Deciphering the Ion Selectivity of the Phosphate Specific Channel OprP from Pseudomonas Aeruginosa: A Free-Energy Molecular Dynamics Simulation Study (2013) (0)
Investigating the Structure-Function Relationship of the Phosphate-Selective Channel OprP (2014) (0)
Inflammation Cells and Controls Cytotoxicity and Induced upon Interaction with Epithelial Two-Component Regulatory System Is The Pseudomonas aeruginosa PhoP-PhoQ (2012) (0)

This paper list is powered by the following services:

Other Resources About Robert E. W. Hancock

What Schools Are Affiliated With Robert E. W. Hancock?

Robert E. W. Hancock is affiliated with the following schools:

Robert E. W. Hancock's Academic­Influence.com Rankings

Robert E. W. Hancock's Degrees

Why Is Robert E. W. Hancock Influential?

Robert E. W. Hancock's Published Works

Published Works

Other Resources About Robert E. W. Hancock

What Schools Are Affiliated With Robert E. W. Hancock?

Image Attributions

Robert E. W. Hancock's AcademicInfluence.com Rankings