Robert G Roeder

Q: What Schools Are Affiliated With Robert G Roeder

Robert G Roeder is affiliated with the following schools: Washington University in St. Louis, University of California, Berkeley, Kyushu University, University of Oxford, California Institute of Technology, Ludwig Maximilian University of Munich, University of Guelph, University of Southern California, Rockefeller University, Baylor College of Medicine

Robert G Roeder's AcademicInfluence.com Rankings

Robert G Roeder

Biology

#1544

World Rank

#2553

Historical Rank

Molecular Biology

#88

World Rank

#91

Historical Rank

Neuroscience

#106

World Rank

#113

Historical Rank

Biochemistry

#109

World Rank

#140

Historical Rank

biology Degrees

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Biology

Robert G Roeder's Degrees

PhD Biochemistry University of California, Berkeley
Bachelors Chemistry University of California, Berkeley

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Robert G Roeder's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. (1983) (10493)
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain (1997) (2613)
Coactivator condensation at super-enhancers links phase separation and gene control (2018) (1303)
The role of general initiation factors in transcription by RNA polymerase II. (1996) (1067)
Human PAD4 Regulates Histone Arginine Methylation Levels via Demethylimination (2004) (993)
Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia (2008) (956)
Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region (1985) (919)
Eukaryotic gene transcription with purified components. (1983) (856)
Multiple Forms of DNA-dependent RNA Polymerase in Eukaryotic Organisms (1969) (840)
WDR5 Associates with Histone H3 Methylated at K4 and Is Essential for H3 K4 Methylation and Vertebrate Development (2005) (834)
Metabolic regulation of gene expression by histone lactylation (2019) (787)
Specific Inhibition of Nuclear RNA Polymerase II by α-Amanitin (1970) (739)
Regulation of MLL1 H3K4 methyltransferase activity by its core components (2006) (728)
Biochemistry and structural biology of transcription factor IID (TFIID). (1996) (724)
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation (2010) (688)
Physical Association and Coordinate Function of the H3 K4 Methyltransferase MLL1 and the H4 K16 Acetyltransferase MOF (2005) (677)
Chromatin structure analyses identify miRNA promoters. (2008) (666)
Synergistic activation of transcription by CBP and p53 (1997) (647)
Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. (1996) (587)
Crystal structure of a TFIIB–TBP–TATA-element ternary complex (1995) (558)
S Phase Activation of the Histone H2B Promoter by OCA-S, a Coactivator Complex that Contains GAPDH as a Key Component (2003) (538)
Ordered Cooperative Functions of PRMT1, p300, and CARM1 in Transcriptional Activation by p53 (2004) (526)
Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes (1980) (519)
The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. (1990) (490)
RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells (2009) (487)
Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation (2008) (478)
Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. (2005) (466)
The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion. (1998) (466)
Selective and accurate initiation of transcription at the ad2 major late promotor in a soluble system dependent on purified rna polymerase ii and dna (1979) (454)
Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. (1999) (448)
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo. (2004) (438)
Cooperative interaction of an initiator-binding transcription initiation factor and the helix–loop–helix activator USF (1991) (436)
The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2. (2002) (426)
Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay. (1985) (416)
Dynamic regulation of pol II transcription by the mammalian Mediator complex. (2005) (415)
Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle (1983) (410)
Multiple factors required for accurate initiation of transcription by purified RNA polymerase II. (1980) (395)
The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly. (1991) (390)
Regulation of the p300 HAT domain via a novel activation loop (2004) (389)
Human STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo (2001) (388)
Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene (1987) (386)
Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells. (2000) (384)
Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID (1988) (381)
Specific nucleolar and nucleoplasmic RNA polymerases. (1970) (378)
Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation. (2015) (374)
Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation (2013) (373)
Crystal structure of TFIID TATA-box binding protein (1992) (370)
HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF. (2000) (363)
Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes (1994) (355)
Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex (1988) (350)
Transcriptional regulation and the role of diverse coactivators in animal cells (2005) (349)
H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation (2013) (344)
A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins. (1988) (338)
mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression. (2003) (330)
Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II (1987) (322)
30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone eviction. (2008) (314)
A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein (1988) (313)
Metabolic Regulation of Gene Expression by Histone Lysine β‐hydroxybutyrylation (2016) (310)
The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions. (2005) (307)
Transcription of class III genes: formation of preinitiation complexes. (1983) (303)
Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product. (1988) (298)
A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation. (1999) (297)
Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation (1998) (295)
Transcription coactivator TRAP220 is required for PPARγ2-stimulated adipogenesis (2002) (292)
Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. (2000) (290)
Activation of class II gene transcription by regulatory factors is potentiated by a novel activity (1991) (289)
Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia (2012) (284)
Family of proteins that interact with TFIID and regulate promoter activity (1991) (283)
Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B (1995) (283)
Role of DNA-dependent RNA polymerase 3 in the transcription of the tRNA and 5S RNA genes. (1974) (282)
p300 and PCAF Act Cooperatively To Mediate Transcriptional Activation from Chromatin Templates by Notch Intracellular Domains In Vitro (2002) (282)
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. (2004) (280)
Crystal structure of a human TATA box-binding protein/TATA element complex. (1996) (278)
GlcNAcylation of histone H2B facilitates its monoubiquitination (2011) (276)
Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro (1987) (267)
Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies. (1991) (266)
Suppression of the antiviral response by an influenza histone mimic (2012) (266)
Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain (1996) (265)
Direct interaction of human TFIID with the HIV-1 transactivator Tat (1994) (264)
Structural similarity between TAFs and the heterotetrameric core of the histone octamer (1996) (261)
Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III (1999) (259)
Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: implications for active repression. (1993) (256)
The TRAP/SMCC/Mediator complex and thyroid hormone receptor function (2001) (255)
Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha. (2003) (254)
Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID) (1990) (254)
The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes (1996) (252)
c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore (1987) (251)
Direct role for Myc in transcription initiation mediated by interactions with TFII-I (1993) (250)
A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors (1992) (249)
Inducible binding of a factor to the c-fos enhancer (1986) (243)
Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro. (1988) (243)
Multiple factors are required for the accurate transcription of purified genes by RNA polymerase III. (1980) (242)
Xenopus 5S gene transcription factor, TFIIIA: Characterization of a cDNA clone and measurement of RNA levels throughout development (1984) (241)
Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration. (2005) (239)
Physical analysis of transcription preinitiation complex assembly on a class II gene promoter. (1988) (238)
Activating Signal Cointegrator 2 Belongs to a Novel Steady-State Complex That Contains a Subset of Trithorax Group Proteins (2003) (236)
Mechanism of action of a yeast activator: Direct effect of GAL4 derivatives on mammalian TFIID-promoter interactions (1988) (233)
MLL associates specifically with a subset of transcriptionally active target genes. (2005) (233)
Structure and function of the b/HLH/Z domain of USF (1994) (232)
The Human PAF1 Complex Acts in Chromatin Transcription Elongation Both Independently and Cooperatively with SII/TFIIS (2010) (231)
Genetic Analysis of Adipogenesis through Peroxisome Proliferator-activated Receptor γ Isoforms* (2002) (228)
Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box (1989) (226)
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3 (2019) (224)
Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. (2012) (223)
Multiple forms of the human gene-specific transcription factor USF. I. Complete purification and identification of USF from HeLa cell nuclei. (1988) (221)
Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain. (2016) (221)
Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis. (2010) (220)
E Protein Silencing by the Leukemogenic AML1-ETO Fusion Protein (2004) (219)
Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains (2011) (216)
Human transcription factor USF stimulates transcription through the initiator elements of the HIV‐1 and the Ad‐ML promoters. (1993) (214)
Ribosomal RNA synthesis in isolated nuclei. (1972) (213)
Structural organization of yeast and mammalian mediator complexes. (2000) (212)
The Leukemogenicity of AML1-ETO Is Dependent on Site-Specific Lysine Acetylation (2011) (209)
Factors involved in specific transcription in mammalian RNA polymerase II. Functional analysis of initiation factors IIA and IID and identification of a new factor operating at sequences downstream of the initiation site. (1987) (208)
Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II. (1985) (206)
Activator-dependent transcription from chromatin in vitro involving targeted histone acetylation by p300. (2000) (206)
Cloning of an Inr‐ and E‐box‐binding protein, TFII‐I, that interacts physically and functionally with USF1 (1997) (206)
A Human SPT3-TAFII31-GCN5-L Acetylase Complex Distinct from Transcription Factor IID* (1998) (201)
Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion (2014) (197)
A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4 (2009) (195)
Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. (1996) (194)
Multiple sequence elements in the c-fos promoter mediate induction by cAMP. (1989) (193)
Faithful transcription of eukaryotic genes by RNA polymerase III in systems reconstituted with purified DNA templates. (1979) (193)
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas. (2017) (192)
A histone octamer-like structure within TFIID (1996) (190)
Topology and reorganization of a human TFIID–promoter complex (1996) (190)
Isolation and partial characterization of the multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in the mouse myeloma, MOPC 315. (1974) (189)
Spermiogenesis Deficiency in Mice Lacking the Trf2 Gene (2001) (189)
Unique TATA‐binding protein‐containing complexes and cofactors involved in transcription by RNA polymerases II and III. (1993) (185)
Role of general and gene-specific cofactors in the regulation of eukaryotic transcription. (1998) (183)
Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes. (1992) (183)
Association of a 5S gene transcription factor with 5S RNA and altered levels of the factor during cell differentiation (1980) (182)
Regulation of TFIIH ATPase and kinase activities by TFIIE during active initiation complex formation (1994) (181)
Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element. (1988) (179)
Targeted inactivation of MLL3 histone H3–Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis (2008) (176)
GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis (2009) (176)
Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases (2006) (175)
Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters (2016) (174)
Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II. (1993) (174)
Structure and function of the b/HLH/Z domain of USF. (1994) (174)
HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors. (1992) (173)
Multiple ribonucleic acid polymerases and ribonucleic acid synthesis during sea urchin development. (1970) (173)
The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein. (1994) (170)
TATA‐binding protein‐associated factor(s) in TFIID function through the initiator to direct basal transcription from a TATA‐less class II promoter. (1994) (170)
Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE. (1987) (170)
Thyroid hormone receptor-associated proteins and general positive cofactors mediate thyroid hormone receptor function in the absence of the TATA box-binding protein-associated factors of TFIID. (1999) (169)
Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation. (1997) (169)
Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis. (2002) (167)
Crystal Structure of Negative Cofactor 2 Recognizing the TBP-DNA Transcription Complex (2001) (166)
The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1 (1993) (165)
Quantitation of RNA Polymerase II and Its Transcription Factors in an HeLa Cell: Little Soluble Holoenzyme but Significant Amounts of Polymerases Attached to the Nuclear Substructure (1999) (165)
RNA polymerase II–associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II (2015) (165)
Multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in Xenopus laevis. Isolation and partial characterization. (1974) (162)
An alternative pathway for transcription initiation involving TFII-I (1993) (161)
Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract. (1987) (161)
Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro. (1997) (159)
Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes (2011) (157)
The 5S gene internal control region is composed of three distinct sequence elements, organized as two functional domains with variable spacing (1987) (157)
Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III. (1988) (156)
Mechanism of Polymerase II Transcription Repression by the Histone Variant macroH2A (2006) (154)
The sarcomeric actin CArG-binding factor is indistinguishable from the c-fos serum response factor (1989) (153)
Activation of transcription factor IIIC by the adenovirus E1A protein (1988) (153)
Heterogeneous expression and functions of androgen receptor co-factors in primary prostate cancer. (2002) (152)
Role of DNA-dependent RNA polymerases II and III in transcription of the adenovirus genome late in productive infection. (1974) (152)
SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53 (2013) (149)
Definition of a novel promoter for the major adenovirus-associated virus mRNA (1980) (147)
Regional and temporal specialization in the nucleus: a transcriptionally‐active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in the cell cycle (1998) (145)
Interaction of TFIID in the minor groove of the TATA element (1991) (144)
The TRAP/Mediator coactivator complex interacts directly with estrogen receptors α and β through the TRAP220 subunit and directly enhances estrogen receptor function in vitro (2002) (143)
The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactions. (1988) (143)
MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. (2005) (143)
AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. (2014) (142)
A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis (2013) (140)
Formation of a rate-limiting intermediate in 5S RNA gene transcription (1985) (137)
Transcriptional regulation by the immediate early protein of pseudorabies virus during in vitro nucleosome assembly (1988) (136)
Control of transcription by Krüppel through interactions with TFIIB and TFIIEβ (1995) (136)
RUNX1 Is a Key Target in t(4;11) Leukemias that Contributes to Gene Activation through an AF4-MLL Complex Interaction (2013) (135)
CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes. (2008) (135)
Multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in Xenopus laevis. Levels of activity during oocyte and embryonic development. (1974) (135)
The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs. (2000) (133)
Human TFIIIC Relieves Chromatin-Mediated Repression of RNA Polymerase III Transcription and Contains an Intrinsic Histone Acetyltransferase Activity (1999) (133)
Analysis of the role of the transcription factor ATF in the assembly of a functional preinitiation complex (1988) (132)
Repression of HIV-1 transcription by a cellular protein. (1991) (131)
Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1) (2011) (131)
Structure, function and expression of a murine homeobox protein AREC3, a homologue of Drosophila sine oculis gene product, and implication in development. (1996) (129)
Requirement of TRAP/Mediator for Both Activator-Independent and Activator-Dependent Transcription in Conjunction with TFIID-Associated TAFIIs (2002) (129)
Enhancement of RNA polymerase III transcription by the E1A gene product of adenovirus (1985) (129)
Specific inhibition of nuclear RNA polymerase II by alpha-amanitin. (1970) (129)
Eukaryotic Nuclear RNA Polymerases (1976) (129)
A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription. (2017) (127)
Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repression (1996) (127)
Arabidopsis thaliana contains two genes for TFIID (1990) (127)
Proximal sequence element-binding transcription factor (PTF) is a multisubunit complex required for transcription of both RNA polymerase II- and RNA polymerase III-dependent small nuclear RNA genes (1995) (126)
Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genes. (1986) (125)
Purification and analysis of a factor which suppresses nick-induced transcription by RNA polymerase II and its identity with poly(ADP-ribose) polymerase. (1983) (125)
An upstream transcription factor, USF (MLTF), facilitates the formation of preinitiation complexes during in vitro chromatin assembly. (1990) (124)
Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains. (1995) (122)
The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development (2002) (121)
CCAAT binding NF-Y-TBP interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues. (1997) (121)
Human TATA-binding protein-related factor-2 (hTRF2) stably associates with hTFIIA in HeLa cells. (1999) (121)
Human Mediator Enhances Basal Transcription by Facilitating Recruitment of Transcription Factor IIB during Preinitiation Complex Assembly* (2006) (121)
The binding of a transcription factor to deletion mutants of a 5S ribosomal RNA gene (1981) (120)
Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms. (2002) (119)
The n-SET domain of Set1 regulates H2B ubiquitylation-dependent H3K4 methylation. (2013) (119)
Direct Bre1-Paf1 Complex Interactions and RING Finger-independent Bre1-Rad6 Interactions Mediate Histone H2B Ubiquitylation in Yeast* (2009) (118)
Phosphorylation of serum response factor, a factor that binds to the serum response element of the c-FOS enhancer. (1988) (118)
The TFIIIC90 Subunit of TFIIIC Interacts with Multiple Components of the RNA Polymerase III Machinery and Contains a Histone-Specific Acetyltransferase Activity (1999) (116)
Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene (1986) (116)
H3R42me2a is a histone modification with positive transcriptional effects (2013) (115)
Purification of the c-fos enhancer-binding protein (1987) (114)
Factors involved in specific transcription by mammalian RNA polymerase II. Transcription factor IIS stimulates elongation of RNA chains. (1987) (114)
Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation. (1994) (114)
Principal Role of TRAP/Mediator and SWI/SNF Complexes in Kaposi's Sarcoma-Associated Herpesvirus RTA-Mediated Lytic Reactivation (2003) (114)
A dynamic model for PC4 coactivator function in RNA polymerase II transcription. (1998) (114)
OCA‐B integrates B cell antigen receptor‐, CD40L‐ and IL 4‐mediated signals for the germinal center pathway of B cell development (1998) (113)
An AP1-binding site in the c-fos gene can mediate induction by epidermal growth factor and 12-O-tetradecanoyl phorbol-13-acetate (1989) (112)
Molecular cloning of Drosophila TFIID subunits (1994) (112)
Transcriptional regulation of the HIV-1 promoter by NF-kappa B in vitro. (1992) (112)
Inhibition of Androgen Receptor-Mediated Transcription by Amino-Terminal Enhancer of split (2001) (111)
Effects of activation-defective TBP mutations on transcription initiation in yeast (1994) (111)
SYT Associates with Human SNF/SWI Complexes and the C-terminal Region of Its Fusion Partner SSX1 Targets Histones* (2002) (111)
Transcription factor TFIID induces DNA bending upon binding to the TATA element. (1992) (111)
A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA. (1993) (110)
A downstream initiation element required for efficient TATA box binding and in vitro function of TFIID (1990) (110)
Analysis of the role of TFIIE in basal transcription and TFIIH-mediated carboxy-terminal domain phosphorylation through structure-function studies of TFIIE-alpha (1995) (109)
Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia. (2015) (109)
The helix-loop-helix/leucine repeat transcription factor USF can be functionally regulated in a redox-dependent manner. (1992) (109)
Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro (1994) (109)
50+ years of eukaryotic transcription: an expanding universe of factors and mechanisms (2019) (105)
TFIIA induces conformational changes in TFIID via interactions with the basic repeat (1992) (105)
The cell type‐specific octamer transcription factor OTF‐2 has two domains required for the activation of transcription. (1990) (104)
Reconstitution of active human core Mediator complex reveals a pivotal role of the MED14 subunit (2014) (104)
Structural and Functional Organization of TRAP220, the TRAP/Mediator Subunit That Is Targeted by Nuclear Receptors (2004) (102)
Energy requirement for specific transcription initiation by the human RNA polymerase II system. (1984) (102)
Low molecular weight viral RNAs transcribed by RNA polymerase III during adenovirus 2 infection (1976) (101)
Transcription activation via enhanced preinitiation complex assembly in a human cell-free system lacking TAFIIs. (1998) (101)
TIP30 has an intrinsic kinase activity required for up‐regulation of a subset of apoptotic genes (2000) (101)
Functional cooperativity between protein molecules bound at two distinct sequence elements of the immunoglobulin heavy-chain promoter (1989) (101)
Selective requirements for histone H3 and H4 N termini in p300-dependent transcriptional activation from chromatin. (2002) (100)
Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters (1990) (99)
The structure of the human histone genes: Clustered but not tandemly repeated (1981) (99)
DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs (2017) (99)
Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia (2013) (98)
Analysis of structure-function relationships of yeast TATA box binding factor TFIID (1990) (98)
TRAP/SMCC/Mediator-Dependent Transcriptional Activation from DNA and Chromatin Templates by Orphan Nuclear Receptor Hepatocyte Nuclear Factor 4 (2002) (98)
SOX9 interacts with a component of the human thyroid hormone receptor-associated protein complex. (2002) (98)
The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro. (2002) (97)
The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220 (2006) (97)
Role of Mediator in Transcriptional Activation by the Aryl Hydrocarbon Receptor* (2004) (95)
Cloning and expression of cDNA for human poly(ADP-ribose) polymerase. (1987) (95)
Drosophila 230-kD TFIID subunit, a functional homolog of the human cell cycle gene product, negatively regulates DNA binding of the TATA box-binding subunit of TFIID. (1993) (94)
Synergistic Functions of SII and p300 in Productive Activator-Dependent Transcription of Chromatin Templates (2006) (94)
PTEN Represses RNA Polymerase III-Dependent Transcription by Targeting the TFIIIB Complex (2008) (93)
Purification and Identification of a Novel Complex Which Is Involved in Androgen Receptor-Dependent Transcription (2003) (93)
Selective and accurate transcription of the Xenopus laevis 5S RNA genes in isolated chromatin by purified RNA polymerase III. (1977) (93)
A stable complex of a novel transcription factor IIB- related factor, human TFIIIB50, and associated proteins mediate selective transcription by RNA polymerase III of genes with upstream promoter elements. (2000) (93)
Alternative Mechanisms by Which Mediator Subunit MED1/TRAP220 Regulates Peroxisome Proliferator-Activated Receptor γ-Stimulated Adipogenesis and Target Gene Expression (2007) (92)
Multiple factors involved in the transcription of class III genes in Xenopus laevis. (1982) (91)
Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase (2002) (91)
DNA topoisomerase I and PC4 can interact with human TFIIIC to promote both accurate termination and transcription reinitiation by RNA polymerase III. (1998) (91)
p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis. (2018) (90)
RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression. (2011) (90)
Mediator-dependent nuclear receptor function. (2011) (89)
Purified octamer binding transcription factors stimulate RNA polymerase III-mediated transcription of the 7SK RNA gene (1989) (89)
Human transcription factor IIIC (TFIIIC). Purification, polypeptide structure, and the involvement of thiol groups in specific DNA binding. (1989) (89)
TIP30 deficiency increases susceptibility to tumorigenesis. (2003) (87)
Core promoter-specific function of a mutant transcription factor TFIID defective in TATA-box binding. (1995) (86)
Involvement of TFIID and USA Components in Transcriptional Activation of the Human Immunodeficiency Virus Promoter by NF-κB and Sp1 (1998) (86)
Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors. (1995) (86)
Genomic organization and nucleotide sequence of two distinct histone gene clusters from Xenopus laevis. Identification of novel conserved upstream sequence elements. (1985) (85)
SWI/SNF remodeling and p300‐dependent transcription of histone variant H2ABbd nucleosomal arrays (2004) (85)
Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase III from the mouse plasmacytoma, MOPC 315. (1975) (85)
Accurate transcription initiation on a purified mouse β-globin DNA fragment in a cell-free system (1980) (85)
Considerations of transcriptional control mechanisms: do TFIID-core promoter complexes recapitulate nucleosome-like functions? (1997) (85)
Structural motifs and potential a homologies in the large subunit of human general transcription factor TFIIE (1991) (85)
TATA-binding Protein Residues Implicated in a Functional Interplay between Negative Cofactor NC2 (Dr1) and General Factors TFIIA and TFIIB (*) (1995) (85)
3' IgH enhancer elements shift synergistic interactions during B cell development. (1998) (84)
Expression and purification of general transcription factors by FLAG epitope-tagging and peptide elution. (1993) (84)
RNA Polymerase III Transcription Repressed by Rb through Its Interactions with TFIIIB and TFIIIC2* (1997) (84)
Fos and jun cooperate in transcriptional regulation via heterologous activation domains (1990) (84)
The ts13 mutation in the TAF(II)250 subunit (CCG1) of TFIID directly affects transcription of D-type cyclin genes in cells arrested in G1 at the nonpermissive temperature (1997) (84)
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. (2012) (83)
The primary structure and expression of four cloned human histone genes. (1983) (83)
OcaB Is Required for Normal Transcription and V(D)J Recombination of a Subset of Immunoglobulin κ Genes (2002) (83)
Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma (2019) (82)
The Cyclin-dependent Kinase-activating Kinase (CAK) Assembly Factor, MAT1, Targets and Enhances CAK Activity on the POU Domains of Octamer Transcription Factors* (1997) (82)
A Mediator-responsive form of metazoan RNA polymerase II. (2006) (81)
Factors involved in specific transcription by mammalian RNA polymerase II: purification and characterization of general transcription factor TFIIE. (1990) (81)
Cloning of the Schizosaccharomyces pombe TFIID gene reveals a strong conservation of functional domains present in Saccharomyces cerevisiae TFIID. (1990) (80)
Identification of an autonomously initiating RNA polymerase III holoenzyme containing a novel factor that is selectively inactivated during protein synthesis inhibition. (1997) (79)
Recombinant 43-kDa USF binds to DNA and activates transcription in a manner indistinguishable from that of natural 43/44-kDa USF (1991) (79)
Stability of transcription complexes on class II genes (1989) (79)
RNA polymerase II cofactor PC2 facilitates activation of transcription by GAL4-AH in vitro (1994) (78)
PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1 (2015) (78)
A novel RNA polymerase II‐containing complex potentiates Tat‐enhanced HIV‐1 transcription (1999) (78)
Engrailed, a homeodomain protein, can repress in vitro transcription by competition with the TATA box-binding protein transcription factor IID. (1990) (77)
A subunit of the mediator complex regulates vertebrate neuronal development (2006) (77)
GAS41 Is Required for Repression of the p53 Tumor Suppressor Pathway during Normal Cellular Proliferation (2006) (77)
Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation (2010) (75)
Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II. (2012) (75)
Octamer transcription factors 1 and 2 each bind to two different functional elements in the immunoglobulin heavy-chain promoter (1989) (75)
A cofactor, TIP30, specifically enhances HIV-1 Tat-activated transcription. (1998) (75)
Functional dissection of TFIIB domains required for TFIIB–TFIID–promoter complex formation and basal transcription activity (1993) (75)
Novel Cofactors and TFIIA Mediate Functional Core Promoter Selectivity by the Human TAFII150-Containing TFIID Complex (1998) (75)
Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription. (1995) (74)
Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis (1984) (74)
Phosphorylation negatively regulates the function of coactivator PC4. (1994) (73)
Altered levels of a 5 S gene-specific transcription factor (TFIIIA) during oogenesis and embryonic development of Xenopus laevis. (1984) (73)
Interaction between the N-terminal domain of the 230-kDa subunit and the TATA box-binding subunit of TFIID negatively regulates TATA-box binding. (1994) (73)
Conserved sequence motifs in the small subunit of human general transcription factor TFIIE (1991) (72)
Distinct nuclear and cytoplasmic functions of androgen receptor cofactor p44 and association with androgen-independent prostate cancer (2008) (72)
Recombinant yeast TFIID, a general transcription factor, mediates activation by the gene-specific factor USF in a chromatin assembly assay. (1990) (72)
Cloning and Characterization of Two Evolutionarily Conserved Subunits (TFIIIC102 and TFIIIC63) of Human TFIIIC and Their Involvement in Functional Interactions with TFIIIB and RNA Polymerase III (1999) (72)
Purification and characterization of two forms of human transcription factor IIIC. (1992) (72)
Distinct transcription factors bind specifically to two regions of the human histone H4 promoter. (1986) (71)
TIP30 Interacts with an Estrogen Receptor α-interacting Coactivator CIA and Regulates c-myc Transcription* (2004) (71)
Sequence of general transcription factor TFIIB and relationships to other initiation factors. (1991) (71)
Transcripts of the adeno-associated virus genome: mapping of the major RNAs (1980) (70)
DNA-dependent RNA polymerase levels during the response of human peripheral lymphocytes to phytohemagglutinin (1975) (70)
Thyroid hormone-induced juxtaposition of regulatory elements/factors and chromatin remodeling of Crabp1 dependent on MED1/TRAP220. (2005) (70)
Potential RNA polymerase II-induced interactions of transcription factor TFIIB (1993) (70)
A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism (2010) (70)
Transcription of cloned Xenopus 5S RNA genes by X. laevis RNA polymerase III in reconstituted systems. (1979) (69)
Complex Regulation of the Transactivation Function of Hypoxia-inducible Factor-1α by Direct Interaction with Two Distinct Domains of the CREB-binding Protein/p300* (2009) (69)
MED14 Tethers Mediator to the N-Terminal Domain of Peroxisome Proliferator-Activated Receptor γ and Is Required for Full Transcriptional Activity and Adipogenesis (2010) (69)
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors (2015) (69)
Cloning and characterization of a TFIIIC2 subunit (TFIIIC beta) whose presence correlates with activation of RNA polymerase III-mediated transcription by adenovirus E1A expression and serum factors. (1995) (68)
MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C. (2016) (68)
A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms (2020) (67)
Activator-dependent transcription by mammalian RNA polymerase II: in vitro reconstitution with general transcription factors and cofactors. (1996) (67)
Purification of a yeast TATA box-binding protein that exhibits human transcription factor IID activity. (1989) (66)
Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription (2010) (66)
A plant DNA-binding protein increases the number of active preinitiation complexes in a human in vitro transcription system. (1990) (66)
TFIIIC1 acts through a downstream region to stabilize TFIIIC2 binding to RNA polymerase III promoters (1996) (66)
Interaction between Cell Cycle Regulator, E2F-1, and NF-κB Mediates Repression of HIV-1 Gene Transcription* (1997) (66)
Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation (2010) (65)
Striking homology of the 'variable' N-terminal as well as the 'conserved core' domains of the mouse and human TATA-factors (TFIID). (1991) (64)
Multivalent Binding of p53 to the STAGA Complex Mediates Coactivator Recruitment after UV Damage (2008) (64)
Drosophila TAF(II)230 and the transcriptional activator VP16 bind competitively to the TATA box-binding domain of the TATA box-binding protein. (1997) (64)
Distinct Transcriptional Activation Functions of STAT1α and STAT1β on DNA and Chromatin Templates* (2003) (63)
Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein (1996) (63)
Analysis of the Role of TFIIE in Transcriptional Regulation through Structure-Function Studies of the TFIIEβ Subunit* (1998) (63)
Role of OCA-B in 3′-IgH Enhancer Function1 (2000) (62)
Reconstitution and transcriptional analysis of chromatin in vitro. (2004) (62)
The eukaryotic transcriptional machinery: complexities and mechanisms unforeseen (2003) (62)
Multiple Forms of RNA Polymerase in Xenopus laevis: Their Relationship to RNA Synthesis in vivo and Their Fidelity of Transcription in vitro (1970) (62)
Distinct molecular structures of nuclear class I, II, and III DNA-dependent RNA polymerases. (1975) (61)
Binding site-dependent direct activation and repression of in vitro transcription by Drosophila homeodomain proteins (1990) (61)
Identification of human TFIID components and direct interaction between a 250-kDa polypeptide and the TATA box-binding protein (TFIID tau). (1992) (61)
Purification and characterization of multiple nuclear factors that bind to the TAX-inducible enhancer within the human T-cell leukemia virus type 1 long terminal repeat (1989) (60)
Definition of the transcriptional activation domain of recombinant 43-kilodalton USF (1992) (59)
Interaction of the human T-cell lymphotropic virus type 1 tax transactivator with transcription factor IIA (1996) (59)
Direct interactions of OCA-B and TFII-I regulate immunoglobulin heavy-chain gene transcription by facilitating enhancer-promoter communication. (2011) (58)
Impaired cell fate through gain-of-function mutations in a chromatin reader (2019) (58)
Cell-type-specific transcription of an immunoglobulin kappa light chain gene in vitro. (1986) (58)
Linker Histone H1.2 cooperates with Cul4A and PAF1 to drive H4K31 ubiquitylation-mediated transactivation. (2013) (58)
Positive and Negative TAFII Functions That Suggest a Dynamic TFIID Structure and Elicit Synergy with TRAPs in Activator-Induced Transcription (2001) (58)
Transcription of human histone genes in extracts from synchronized HeLa cells. (1984) (57)
Factors involved in specific transcription by mammalian RNA polymerase II: identification of general transcription factor TFIIG. (1990) (57)
Dynamic interactions and cooperative functions of PGC-1alpha and MED1 in TRalpha-mediated activation of the brown-fat-specific UCP-1 gene. (2009) (56)
USF1 and hSET1A Mediated Epigenetic Modifications Regulate Lineage Differentiation and HoxB4 Transcription (2013) (56)
Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC (1994) (56)
MCEF, the Newest Member of the AF4 Family of Transcription Factors Involved in Leukemia, Is a Positive Transcription Elongation Factor-b-Associated Protein (2002) (55)
The Hepatitis B Virus X Protein Is a Co-activator of Activated Transcription That Modulates the Transcription Machinery and Distal Binding Activators* (1998) (55)
Nuclear RNA polymerases: role of general initiation factors and cofactors in eukaryotic transcription. (1996) (54)
Control of class II gene transcription during in vitro nucleosome assembly. (1991) (54)
Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95 (2013) (54)
The STAGA Subunit ADA2b Is an Important Regulator of Human GCN5 Catalysis (2008) (53)
Structural and Functional Characterization of PC2 and RNA Polymerase II-Associated Subpopulations of Metazoan Mediator (2005) (53)
Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia (2008) (52)
Epitopes of the p70 and p80 (Ku) lupus autoantigens. (1991) (52)
Histone H3K27 Trimethylation Inhibits H3 Binding and Function of SET1-Like H3K4 Methyltransferase Complexes (2013) (52)
Coactivation by OCA-B: Definition of Critical Regions and Synergism with General Cofactors (1998) (52)
Isolation and functional characterization of the TRAP/mediator complex. (2003) (52)
Crystal structure of the C-terminal domain of the RAP74 subunit of human transcription factor IIF (2001) (52)
cDNA clone encoding Drosophila transcription factor TFIID. (1990) (52)
The regulatory enzymes and protein substrates for the lysine β-hydroxybutyrylation pathway (2021) (51)
Transcription factor TFIIB sites important for interaction with promoter-bound TFIID. (1993) (51)
A bipartite DNA binding domain composed of direct repeats in the TATA box binding factor TFIID. (1992) (51)
Specific Interactions and Potential Functions of Human TAFII100* (1997) (50)
Identification of TFIID components required for transcriptional activation by upstream stimulatory factor. (1993) (50)
Histone H1 acetylation at lysine 85 regulates chromatin condensation and genome stability upon DNA damage (2018) (49)
Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF (2003) (49)
Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription. (2016) (48)
Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma. (2018) (48)
Positive and negative regulation of the gene for transcription factor IIIA in Xenopus laevis oocytes. (1989) (48)
Enhancer-promoter communication and transcriptional regulation of Igh. (2011) (48)
Assembly and DNA binding of recombinant Ku (p70/p80) autoantigen defined by a novel monoclonal antibody specific for p70/p80 heterodimers. (1994) (47)
TATA-Binding Protein (TBP)-Like Factor (TLF) Is a Functional Regulator of Transcription: Reciprocal Regulation of the Neurofibromatosis Type 1 and c-fos Genes by TLF/TRF2 and TBP (2005) (46)
Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes (2012) (46)
The C-terminal domain-phosphorylated IIO form of RNA polymerase II is associated with the transcription repressor NC2 (Dr1/DRAP1) and is required for transcription activation in human nuclear extracts. (2000) (46)
Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets (2018) (46)
p53 requires an intact C-terminal domain for DNA binding and transactivation. (2012) (45)
Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth (2012) (45)
Cloning and Characterization of Human TAF20/15 (1996) (45)
A quick procedure for purification of functional recombinant proteins over-expressed in E.coli. (1991) (44)
TFII-I Regulates Induction of Chromosomally Integrated Human Immunodeficiency Virus Type 1 Long Terminal Repeat in Cooperation with USF (2005) (44)
Characterization of the human β-globin downstream promoter region (2003) (44)
The Xenopus B1 factor is closely related to the mammalian activator USF and is implicated in the developmental regulation of TFIIIA gene expression. (1991) (44)
TATA-Binding Protein-Interacting Protein 120, TIP120, Stimulates Three Classes of Eukaryotic Transcription via a Unique Mechanism (1999) (43)
A Novel LBP-1-mediated Restriction of HIV-1 Transcription at the Level of Elongation in Vitro(*) (1995) (43)
Transcriptional activation in yeast by the proline-rich activation domain of human CTF1. (1993) (42)
Transcription of adenovirus type 2 genes in a cell-free system: apparent heterogeneity of initiation at some promoters (1981) (42)
The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain (2006) (42)
RNA polymerase III in Cajal bodies and lampbrush chromosomes of the Xenopus oocyte nucleus. (2002) (41)
The conserved carboxy-terminal domain of Saccharomyces cerevisiae TFIID is sufficient to support normal cell growth (1991) (41)
Xenopus laevis histone genes: Variant H1 genes are present in different clusters (1980) (40)
The Mediator subunit MED1/TRAP220 is required for optimal glucocorticoid receptor-mediated transcription activation (2007) (40)
Cloning and characterization of the beta subunit of human proximal sequence element-binding transcription factor and its involvement in transcription of small nuclear RNA genes by RNA polymerases II and III (1996) (40)
Cell- and stage-specific high-level expression of TBP-related factor 2 (TRF2) during mouse spermatogenesis (2001) (40)
The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing. (2019) (40)
Molecular cloning, expression, and characterization of the Drosophila 85-kilodalton TFIID subunit (1993) (40)
In vitro stimulation of specific RNA polymerase II-mediated transcription by the pseudorabies virus immediate early protein (1985) (39)
Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin (2015) (39)
Physical properties and DNA-binding stoichiometry of a 5 S gene-specific transcription factor. (1984) (39)
Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase III from the posterior silk gland of Bombyx mori. (1976) (39)
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis (2022) (39)
Viral RNA Synthesis and Levels of DNA-Dependent RNA Polymerases During Replication of Adenovirus 2 (1976) (39)
The SANT Domain of p400 ATPase Represses Acetyltransferase Activity and Coactivator Function of TIP60 in Basal p21 Gene Expression (2010) (39)
Encephalomyocarditis Virus Infection of Mouse Plasmacytoma Cells II. Effect on Host RNA Synthesis and RNA Polymerases (1974) (38)
Nontranscriptional Regulation of SYK by the Coactivator OCA-B Is Required at Multiple Stages of B Cell Development (2006) (38)
Gene-Specific Control of tRNA Expression by RNA Polymerase II. (2020) (38)
Utilization of signal transduction pathway by the human T-cell leukemia virus type I transcriptional activator tax (1989) (38)
The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter. (1989) (38)
The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis. (2003) (38)
Direct link between metabolic regulation and the heat-shock response through the transcriptional regulator PGC-1α (2015) (38)
TATA Box Mimicry by TFIID Autoinhibition of Pol II Transcription (1998) (37)
Transcription of specific genes in isolated nuclei by exogenous RNA polymerases (1977) (37)
Different Functional Modes of p300 in Activation of RNA Polymerase III Transcription from Chromatin Templates (2008) (37)
The upstream stimulatory factor functionally interacts with the Alzheimer amyloid beta-protein precursor gene. (1995) (36)
Nuclear factor 1 (NF1) affects accurate termination and multiple‐round transcription by human RNA polymerase III (2000) (36)
Acetylation of p 53 augments its site-specific DNA binding both in vitro and in vivo (2004) (36)
Transcription of viral genes by RNA polymerase II in nuclei isolated from adenovirus 2 transformed cells. (1978) (36)
Interaction of the B Cell-specific Transcriptional Coactivator OCA-B and Galectin-1 and a Possible Role in Regulating BCR-mediated B Cell Proliferation* (2006) (36)
Roles of histone H3-lysine 4 methyltransferase complexes in NR-mediated gene transcription. (2009) (35)
Mediator Subunits MED1 and MED24 Cooperatively Contribute to Pubertal Mammary Gland Development and Growth of Breast Carcinoma Cells (2012) (35)
Identification and characterization of a novel OCA-B isoform. implications for a role in B cell signaling pathways. (2001) (34)
Transcripts of the adenovirus-associated virus genome: multiple polyadenylated RNAs including a potential primary transcript (1980) (34)
Sarkosyl defines three intermediate steps in transcription initiation by RNA polymerase III: application to stimulation of transcription by E1A. (1990) (34)
Purification, properties, and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase III from uninfected and adenovirus 2-infected KB cells. (1977) (34)
The Mediator subunit MED23 couples H2B mono‐ubiquitination to transcriptional control and cell fate determination (2015) (33)
A Feed-Forward Repression Mechanism Anchors the Sin3/Histone Deacetylase and N-CoR/SMRT Corepressors on Chromatin (2006) (33)
Upstream stimulating factor affects human immunodeficiency virus type 1 (HIV-1) long terminal repeat-directed transcription in a cell-specific manner, independently of the HIV-1 subtype and the core-negative regulatory element. (2001) (33)
DNA sequences and transcription factor interactions of active and inactive forms of mammalian 5 S RNA genes. (1984) (33)
The role of transcriptional coactivator TRAP220 in myelomonocytic differentiation (2005) (33)
The major histocompatibility complex class II Ea promoter requires TFIID binding to an initiator sequence (1996) (32)
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF (2019) (32)
Isolation and characterization of a cDNA encoding Drosophila transcription factor TFIIB. (1992) (30)
A TAF4 coactivator function for E proteins that involves enhanced TFIID binding. (2013) (29)
Direct Association of p300 with Unmodified H3 and H4 N Termini Modulates p300-dependent Acetylation and Transcription of Nucleosomal Templates* (2003) (29)
CTD-like sequences are important for transcriptional activation by the proline-rich activation domain of CTF1. (1994) (29)
Transcription of the β-like globin genes and pseudogenes of the goat in a cell-free system (1981) (29)
Identification of transcription coactivator OCA-B-dependent genes involved in antigen-dependent B cell differentiation by cDNA array analyses (2003) (29)
Gene-Specific H1 Eviction through a Transcriptional Activator→p300→NAP1→H1 Pathway. (2019) (28)
Transcriptionally active immediate-early protein of pseudorabies virus binds to specific sites on class II gene promoters (1989) (28)
Distinct transcriptional activation functions of STAT1alpha and STAT1beta on DNA and chromatin templates. (2003) (28)
The GAS41-PP2Cβ Complex Dephosphorylates p53 at Serine 366 and Regulates Its Stability* (2011) (27)
A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass (2018) (27)
Functional Analysis of the OCA-B Promoter1 (2000) (27)
Purification and characterization of human transcription factor IIIA. (1994) (26)
The Drosophila 110-kDa transcription factor TFIID subunit directly interacts with the N-terminal region of the 230-kDa subunit. (1993) (26)
Serum response factor affects preinitiation complex formation by TFIID in vitro. (1991) (26)
Expression of the autonomous parvovirus H1 genome: Evidence for a single transcriptional unit and multiple spliced polyadenylated transcripts (1979) (26)
Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase II from the mouse plasmacytoma, MOPC 315. (1975) (25)
DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2. (1982) (25)
Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1 (2018) (25)
Multiple forms of DNA-dependent RNA polymerases in Xenopus laevis. Rapid purification and structural and immunological properties. (1983) (25)
Identification of an octamer-binding site in the mouse kappa light-chain immunoglobulin enhancer (1989) (25)
Isolation and characterization of monoclonal antibodies directed against subunits of human RNA polymerases I, II, and III. (2000) (24)
Involvement of the basic repeat domain of TATA-binding protein (TBP) in transcription by RNA polymerases I, II, and III. (1994) (24)
Characterization of the human beta-globin downstream promoter region. (2003) (24)
Core promoter-selective function of HMGA1 and Mediator in Initiator-dependent transcription. (2011) (24)
Activation of the adenovirus EIIa late promoter by a single-point mutation which enhances binding of transcription factor IID. (1988) (24)
Transcriptional regulation of c-fos. (1988) (23)
Transformation by homeobox genes can be mediated by selective transcriptional repression. (1994) (23)
Transcription Factor (TF)-like Nuclear Regulator, the 250-kDa Form of Homo sapiens TFIIIB″, Is an Essential Component of Human TFIIIC1 Activity* (2004) (23)
Structural relationships of low molecular weight viral RNAs synthesized by RNA polymerase III in nuclei from adenovirus 2-infected cells. (1978) (23)
Stable transcription complex on a class III gene in a minichromosome (1985) (22)
Transcription of specific adenovirus genes in isolated nuclei by exogenous RNA polymerases. (1977) (22)
Isolation and genomic arrangement of active and inactive forms of mammalian 5 S RNA genes. (1984) (21)
Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout (2021) (21)
Nucleosomal H2B ubiquitylation with purified factors. (2011) (21)
Genomics and transcription analysis of human TFIID (1998) (20)
Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation. (2018) (20)
Mediator: A Drawbridge across the Enhancer-Promoter Divide. (2016) (20)
Regulation of RNA polymerase III transcription during transformation of human IMR90 fibroblasts with defined genetic elements (2018) (20)
MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition (2019) (20)
A novel TBP-TAF complex on RNA Polymerase II-transcribed snRNA genes (2012) (20)
Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation. (2006) (20)
Genetic and biochemical analyses of yeast TATA-binding protein mutants. (1993) (20)
The transcriptional role of host DNA-dependent RNA polymerases in adenovirus-infected KB cells. (1975) (19)
Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase I from the mouse myeloma, MOPC 315. (1974) (19)
Faithful gene transcription by eukaryotic RNA polymerases in reconstructed systems. (1978) (19)
Multiple proteins bind to VA RNA genes of adenovirus type 2 (1987) (18)
ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase. (2020) (18)
p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis. (2018) (18)
Independent control of transcription initiations from two sites by an initiator‐like element and TATA box in the human c‐erb B‐2 promoter (1994) (17)
B-cell-specific coactivator OCA-B: biochemical aspects, role in B-cell development and beyond. (1999) (17)
Conserved structural motifs within the N-terminal domain of TFIID tau from Xenopus, mouse and human. (1992) (17)
Downstream Promoter Sequences Facilitate the Formation of a Specific Transcription Factor IID-Promoter Complex Topology Required for Efficient Transcription from the Megalin/Low Density Lipoprotein Receptor-related Protein 2 Promoter* (2000) (17)
AID–RNA polymerase II transcription-dependent deamination of IgV DNA (2019) (17)
Genetic Analyses of NFKB1 and OCA-B Function: Defects in B Cells, Serum IgM Level, and Antibody Responses in Nfkb1−/−Oca-b−/− Mice1 (2000) (17)
Multivalent Role of Human TFIID in Recruiting Elongation Components at the Promoter-Proximal Region for Transcriptional Control. (2019) (17)
Function, structure, and regulation of eukaryotic nuclear RNA polymerases. (1976) (16)
E2A-PBX1 functions as a coactivator for RUNX1 in acute lymphoblastic leukemia. (2020) (16)
Identification of USF as the ubiquitous murine factor that binds to and stimulates transcription from the immunoglobulin lambda 2-chain promoter. (1992) (16)
Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology (2018) (15)
DOT1L complex regulates transcriptional initiation in human erythroleukemic cells (2021) (15)
Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis (2018) (15)
Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage. (2020) (15)
The Human Homologue of Drosophila TRF-proximal Protein Is Associated with an RNA Polymerase II-SRB Complex* (1999) (15)
The gene-specific initiation factor USF (upstream stimulatory factor) bound at the adenovirus type 2 major late promoter: mass and three-dimensional structure. (1987) (14)
Functions of paralogous RNA polymerase III subunits POLR3G and POLR3GL in mouse development (2020) (14)
Anti-IgM antibodies down modulate mu-enhancer activity and OTF2 levels in LPS-stimulated mouse splenic B-cells. (1991) (14)
Conserved structural motifs between Xenopus and human TFIIB. (1991) (14)
Interactions of the HIV-1 Tat and RAP74 proteins with the RNA polymerase II CTD phosphatase FCP1. (2005) (14)
Parvovirus H-1 expression: mapping of the abundant cytoplasmic transcripts and identification of promoter sites and overlapping transcription units (1986) (14)
The use of monoclonal antibodies for the characterization of a 5 S gene-specific transcription factor (IIIA) from Xenopus laevis. (1983) (13)
The Transcriptional Mediator Subunit MED1/TRAP220 in Stromal Cells Is Involved in Hematopoietic Stem/Progenitor Cell Support through Osteopontin Expression (2010) (13)
Transcription of in vitro assembled chromatin templates in a highly purified RNA polymerase II system. (2009) (13)
CCAR1/CoCoA pair‐mediated recruitment of the Mediator defines a novel pathway for GATA1 function (2014) (12)
Major transitions in histone gene expression do not occur during development in Xenopus laevis. (1986) (12)
Mediator subunit MED1 is required for E2A-PBX1–mediated oncogenic transcription and leukemic cell growth (2021) (12)
Nucleotide and amino acid sequence of RAP30. (1991) (12)
Identification of a novel factor that interacts with an immunoglobulin heavy-chain promoter and stimulates transcription in conjunction with the lymphoid cell-specific factor OTF2. (1990) (12)
AFF1 acetylation by p300 temporally inhibits transcription during genotoxic stress response (2019) (11)
Yeast transcription factor IID participates in cell-free transcription of a mammalian ribosomal protein TATA-less promoter. (1992) (11)
Overlapping transcription by RNA polymerases II and III of the Xenopus TFIIIA gene in somatic cells. (1994) (11)
Neonatal induction of a nuclear protein that binds to the c-fos enhancer. (1989) (11)
Epigenetics? Mediator does that too! (2008) (11)
Transcription factor OTF-1 interacts with two distinct DNA elements in the A gamma-globin gene promoter. (1991) (11)
Role of DNA-Dependent RNA Polymerase III in the Transcription of the tRNA and 5 S RNA Genes ( mouse myeloma cells / isolated nuclei / a-amanitin ) (11)
Multiple forms of DNA-dependent RNA polymerases in Xenopus laevis. Properties, purification, and subunit structure of class III RNA polymerases. (1983) (9)
Identification of human TFIID components and direct interaction between a 250-kDa polypeptide and the TATA box-binding protein ( TFIIDT ) ( RNA polymerase li / transcriptional action / tr ti inittion / subunit structure ) (9)
Functional significance of the TATA element major groove in transcription initiation by RNA polymerase II. (1997) (9)
Elucidation of three putative structural subdomains by comparison of primary structure of Xenopus and human RAP74. (1992) (9)
Direct binding of yeast transcription factor (TFIID) to the ribosomal protein L32 (rpL32) TATA‐less promoter sequence (1993) (9)
FGF7 supports hematopoietic stem and progenitor cells and niche-dependent myeloblastoma cells via autocrine action on bone marrow stromal cells in vitro. (2013) (9)
The STAGA Subunit ADA 2 b Is an Important Regulator of Human GCN 5 Catalysis † (2008) (9)
Periostin supports hematopoietic progenitor cells and niche-dependent myeloblastoma cells in vitro. (2016) (9)
MLL-AF 9 – and HOXA 9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD 1 C (2018) (9)
FACTORS INVOLVED IN THE TRANSCRIPTION OF PURIFIED GENES BY RNA POLYMERASE III (1979) (9)
Delineation of DNA sequences that are important for in vitro transcription from the adenovirus EIIa late promoter (1988) (8)
Genes for human general transcription initiation factors TFIIIB, TFIIIB-associated proteins, TFIIIC2 and PTF/SNAPC: functional and positional candidates for tumour predisposition or inherited genetic diseases? (2001) (8)
Two forms of transcription factor TFIIIC in extracts from HeLa cells (1987) (8)
Three organizations of human DNA. (1983) (8)
Structural conservation of putative functional motifs between Xenopus and human TFILLE-β (1992) (8)
Functional partitioning of transcriptional regulators by patterned charge blocks (2022) (8)
Human GLI-2 Is a Tat Activation Response Element-Independent Tat Cofactor (2001) (7)
Characterization of the highly conserved TFIIA small subunit from Drosophila melanogaster. (1994) (7)
OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity (2021) (7)
Characterization of the nucleotide requirement for elimination of the rate-limiting step in 5 S RNA gene transcription. (1986) (7)
Characterization of the Core Promoter of the Na+/K+-ATPase α1 Subunit Gene (1996) (7)
Function and Regulation of RNA Polymerases II and III in Adenovirus-infected KB Cells (1976) (6)
SELECTIVE TRANSCRIPTION OF THE 5S RNA GENES IN ISOLATED CHROMATIN BY RNA POLYMERASE III (1976) (6)
STRUCTURE, FUNCTION, AND REGULATION OF RNA POLYMERASES IN ANIMAL CELLS (1975) (6)
Destabilization of AETFC through C/EBPα-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation (2019) (6)
Oscillatory stress stimulation uncovers an Achilles ’ heel of the yeast MAPK signaling network (2016) (6)
An RNA Polymerase III-defective Mutation in TATA-binding Protein Disrupts Its Interaction with a Transcription Factor IIIB Subunit inDrosophila Cells* (1997) (6)
Identification of two large subdomains in TFIIE-alpha on the basis of homology between Xenopus and human sequences. (1992) (6)
Novobiocin interferes with the binding of transcription factors TFIIIA and TFIIIC to the promoters of class III genes. (1987) (6)
Molecular Structures of Eukaryotic Class III RNA Polymerases (1976) (6)
A PRC2-Kdm5b axis sustains tumorigenicity of acute myeloid leukemia (2022) (5)
Retraction: GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis (2013) (5)
Transcriptional regulation of the HIV-1 promoter by NF-KB in vitro (2007) (5)
Transcription of viral genes in chromatin from adenovirus 2 transformed cells by exogenous eukaryotic RNA polymerases. (1979) (5)
Transcriptional down-regulation of metabolic genes by Gdown1 ablation induces quiescent cell re-entry into the cell cycle (2020) (5)
A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor γ Binding Properties and Biological Activities. (2020) (5)
ANALYSIS OF EUKARYOTIC GENE TRANSCRIPTION IN VITRO (1981) (5)
Anupstreamtranscription factor, USF(MLTF), facilitates theformation ofpreinitiation complexes during invitro chromatin assembly (1990) (5)
A histone-like motif in yellow fever virus contributes to viral replication (2020) (4)
Transcription of the beta-like globin genes and pseudogenes of the goat in a cell-free system. (1981) (4)
Critical Role of the Second Stirrup Region of the TATA-binding Protein for Transcriptional Activation Both in Yeast and Human* (1997) (4)
Induced RPB1 depletion reveals a direct gene-specific control of RNA Polymerase III function by RNA Polymerase II (2019) (4)
Regulation of hepatocyte cell cycle re-entry by RNA polymerase II-associated Gdown1 (2020) (4)
The Long and the Short of BRD4: Two Tales in Breast Cancer. (2020) (4)
Severely Impaired Erythropoiesis in Mice Lacking Mediator Subunit Med1/TRAP220. (2004) (3)
Two target gene activation pathways for orphan ERR nuclear receptors (2023) (3)
Efficacy of a small molecule inhibitor of the transcriptional cofactor PC4 in prevention and treatment of non-small cell lung cancer (2020) (3)
Critical roles of transcriptional coactivator MED1 in the formation and function of mouse adipose tissues (2021) (3)
Role of dna-dependent rna polymerase iii in 5s and 4s rna synthesis. Abstr. (1974) (3)
Initiator element binding protein TFII-I: a tale of two sites. (1994) (3)
Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling (2021) (3)
Inhibition of Adhesion Molecule Gene Expression and Cell Adhesion by the Metabolic Regulator PGC-1α (2016) (3)
Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter. (2013) (2)
Selective Requirements for Histone H 3 and H 4 N Termini in p 300-Dependent Transcriptional Activation (2002) (2)
transcription factor IIA . virus type 1 tax transactivator with Interaction of the human T-cell lymphotropic (1996) (2)
The CTD Is Not Essential for the Post-Initiation Control of pol II Activity. (2020) (2)
Robert G. Roeder Receives 2003 Albert Lasker Award for Basic Medical Research (2004) (2)
Structural conservation of putative functional motifs between Xenopus and human TFIIE-beta. (1992) (2)
The SANT Domain of p 400 ATPase Represses Acetyltransferase Activity and Coactivator Function of TIP 60 in Basal p 21 Gene Expression (2010) (2)
CHAPTER 271 – Regulation of Basal Transcription by RNA Polymerase II (2003) (2)
USF 1 and hSET 1 A Mediated Epigenetic Modifications Regulate Lineage Differentiation and HoxB 4 Transcription (2013) (2)
Imperfect conservation of a sigma factor-like subregion in Xenopus general transcription factor RAP30. (1992) (2)
A non-canonical-PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass (2018) (2)
DOT1L Complex Regulates Transcriptional Initiation in Human Cells (2020) (2)
Proline-rich activator CTF 1 targets the TFIIB assembly step during transcriptional activation ( transcription / regulation / protenprotein (2004) (2)
Imperfect conservation of a sigma factor-like subregion in Xenopus general transcription factor RAP30 (1992) (2)
5 – Animal Nuclear RNA Polymerases (1977) (2)
Chromatin and Transcriptional Tango on the Immune Dance Floor (2014) (2)
HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA (1996) (1)
Targeting chromatin kinases reveals their role in inducible transcription of inflammatory genes (2016) (1)
Periostin Supports Hematopoietic Stem/Progenitor Cells and Niche-Dependent Myeloblastoma Cells In Vitro (2016) (1)
Characterization of the core promoter of the Na+/K(+)-ATPase alpha 1 subunit gene. Elements required for transcription by RNA polymerase II and RNA polymerase III in vitro. (1996) (1)
Eukaryotic transcription mechanisms: from nuclear RNA polymerases to general initiation factors, gene‐specific activators, coactivators and chromatin (2016) (1)
The HTLV‐I Tax‐Inducible Enhancer Is Responsive to Various Inducing Agents (1989) (1)
Transcription of chromatin in isolated nuclei by exogenous RNA polymerases (1978) (1)
The CTD is not essential for the post-initiation control of RNA Polymerase II activity (2020) (1)
A direct comparison between AML1-ETO and ETO2-GLIS2 leukemia fusion proteins reveals context-dependent binding and regulation of target genes and opposite functions in cell differentiation (2022) (1)
Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains (2011) (1)
Control of Secreted Protein Gene Expression and the Mammalian Secretome by the Metabolic Regulator PGC-1α* (2016) (1)
Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts (2021) (1)
Cloning and expression of cDNA for human poly(ADP-ribose) (2016) (1)
50+ years of eukaryotic transcription: an expanding universe of factors and mechanisms (2019) (0)
Metabolic markers expressed in mice where MED1 nuclear receptor recognition motifs are defeated (2017) (0)
Issue Information (2022) (0)
Transcription of Class III Genes: Formation of Preinitiation Complexes (2019) (0)
Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes (1992) (0)
Issue Information (2021) (0)
PML–RARα induces all-trans retinoic acid-dependent transcriptional activation through interaction with MED1 (2019) (0)
Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B cell fate decisions and yields T cell-depleted lymphomas (2023) (0)
The Role of Transcriptional Coactivator TRAP220/MED1 in Nuclear Receptor-Mediated Myelomonocytic Differentiation. (2005) (0)
Issue Information (2021) (0)
Selective and accurate transcription of the Xenopus laevis 5 S RNA genes in isolated chromatin by purified RNA polymerase III * ( Xenopus laevis oocytes / homologous and heterologous RNA polymerases / discrete products / asymmetric transcription ) (0)
Ubiquitylation in Yeast Interactions Mediate Histone H 2 B RING Finger-independent Bre 1-Rad 6 Direct Bre 1-Paf 1 Complex Interactions and Epigenetics : Transcription , Chromatin (2009) (0)
Have Your PIC! (2013) (0)
Issue Information (2022) (0)
Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO (2006) (0)
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis (2022) (0)
A Unified Nomenclature for Protein Subunits of Mediator Complexes Conserved from Fungi to Humans: Med6/pmc5/arc/ Drip33/trap32, Med7/arc/drip/trap34/crsp33, Linking Transcriptional Regulators to Rna Polymerase Ii Arc/crsp/drip150/trap170, Soh1/trap18 (note That Soh1 Has Not Been yet Identified in Pu (0)
Issue Information (2022) (0)
RNA Pol II(G) (2019) (0)
function ofamutanttranscription factor TFIIDdefective inTATA-boxbinding (1995) (0)
Issue Information (2021) (0)
Issue Information (2021) (0)
The source file for unprocessed immuno-blots for MOLECULAR-CELL-D-17-01671 (2018) (0)
DNA sequences affecting, specific ii from the EIII promoter of adenovir (2016) (0)
Utilization ofSignal Transduction PathwaybytheHumanT-Cell Leukemia VirusTypeITranscriptional Activator tax (1989) (0)
核レセプター,癌抑制遺伝子p53,およびB細胞分化特異的シグナルによる転写調節の機構 (1999) (0)
Correction for Malik et al., “Structural and Functional Organization of TRAP220, the TRAP/Mediator Subunit That Is Targeted by Nuclear Receptors” (2022) (0)
Transcriptional Regulation of the Neurofibromatosis Type 1 Gene (2003) (0)
Cell Cycle Progression and Signal Transduction in Normal and IgM Transgenic B Cells (1995) (0)
LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML (2022) (0)
TCL1 sensitizes B cells to transformation by a pathway requiring germinal center passage and induction of genomic instability (2006) (0)
Mediator-Dependent Transcriptional Activation by Estrogen Receptor Bound to Distal Enhancers (2015) (0)
Issue Information (2021) (0)
Recombinant 43-Kilodalton USF (0)
Identification and Purification of Multiple HTLV‐I Tax‐Inducible Enhancer Binding Proteins (1989) (0)
Transcriptional Regulatory Mechanisms in Animal Cells (2010) (0)
Issue Information (2022) (0)
Issue Information (2021) (0)
An OCT2 / OCA-B / MEF2B Ternary Complex Controls the Activity and Architecture of an Essential Locus Control Region for Normal and Malignant Germinal Center B-Cells. (2019) (0)
Role of TRAP/Mediator complex in nuclear receptor functions and morphogenesis (2004) (0)
The Acetylation of AML1-ETO Is Required for Leukemogenesis. (2010) (0)
The Three E Proteins Define a Heterogeneity of the AML1-ETO-Containing Transcription Factor Complex (AETFC) and Differentially Regulate t(8;21) Leukemogenesis (2018) (0)
Binding Site-Dependent Dimct Activation and Fkpssion of In Vitro liranscriptiun by a Homeodomain Proteins (1990) (0)
Cloning of the Schizosaccharomyces pombe TF.IID gene reveals a strong conservauon of functional domains present in Saccharomyces cerevisiae (2007) (0)
TFIIB (HUMAN CORE DOMAIN)/TBP (A.THALIANA)/TATA ELEMENT TERNARY COMPLEX (1996) (0)
Crystal Structure of the NC2-TBP-DNA Ternary Complex (2001) (0)
Contents continued (2022) (0)
Proteinsa Subset of Trithorax Group a Novel Steady-State Complex That Activating Signal Cointegrator 2 Belongs to (2014) (0)
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3 (2019) (0)
Impaired cell fate through gain-of-function mutations in a chromatin reader (2019) (0)
A Glycine-Dependent Riboswitch That Uses Cooperative Binding to Control Gene Expression (0)
INITIATION OF TRANSCRIPTION IN EUKARYOTES (1981) (0)
RoleofDNA-Dependent RNA Polymerase IIIintheTranscription of thetRNAand5SRNA Genes (mousemyelomacells/isolated nuclei/a-amanitin) (1974) (0)
The Xenopus B1 factor is closely related to the mammalian activator USF and is implicated in the developmental regulation of TFIIIA gene expression (1991) (0)
regulation Myc enhancer-mediated Role of SWI / SNF in acute leukemia maintenance and Material Supplemental (2013) (0)
Genetic Analyses of NFKB1 and OCA-B (2000) (0)
Issue Information (2021) (0)
The acute myeloid leukemia fusion protein AML1-ETO targets E-proteins via a PAH-like TAFH domain (2006) (0)
Initiation of Eukaryotic Gene Transcription in Vitro (1981) (0)
MED1 independent activation of endogenous target genes by PPARα (2008) (0)
Nfkb 1 Level , and Antibody Responses in Function : Defects in B Cells , Serum IgM Genetic Analyses of NFKB 1 and OCA-B (2000) (0)
This information is current as-IgH Enhancer Function ′ Role of OCA-B in 3 and (2000) (0)
Non-Catalytic Role of SETD1A Regulates DNA Repair in Leukemia (2016) (0)
Structural basis of human SNAPc recognizing proximal sequence element of snRNA promoter (2022) (0)
MED1 regulates mobilization of IL-33 induced type 2 innate lymphoid cells (2017) (0)
Issue Information (2021) (0)
Cloning and Characterization of the (cid:98) Subunit of Human Proximal Sequence Element-Binding Transcription Factor and Its Involvement in Transcription of Small Nuclear RNA Genes by RNA Polymerases II and III (1996) (0)
Targeting Pre-B Cell Receptor and BCL6 In TCF3-PBX1 B-Lineage Acute Lymphoblastic Leukemia (2013) (0)
Nuclear receptor binding capacity of MED1 is required for maintaining body temperature at cold environment (2017) (0)
Role of hSET1 Complex in Epigenetic Controls of HoxB4 Expression and Development of Hematopoietic Stem Cells (2011) (0)
Metabolic Regulation of G ene Expression by Histone Lysine b-Hydroxybutyrylation Graphical Abstract Highlights (2016) (0)
Issue Information (2023) (0)
and 12-O-tetradecanoyl phorbol-13-acetate. mediate induction by epidermal growth factor An AP1-binding site in the c-fos gene can (2013) (0)
Phosphorylated MED1 links transcription recycling and cancer growth (2022) (0)
TIP 30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes molecular mechanism by which the CC 3 gene mediates (2013) (0)
Octamer Transcription Factors 1and2EachBindtoTwoDifferent Functional Elements intheImmunoglobulin Heavy-Chain Promoter (1989) (0)
Self-Enforcing Feedback Activation Between BCL6 and Tonic Pre-B Cell Receptor Signaling in Acute Lymphoblastic Leukemia (2014) (0)
Identification of a novel factor that interacts with an immunoglobulin heavy-chain promoter and stimulates transcription in conjunction with the lymphoid cell-specific factor OTF2 (1990) (0)
Issue Information (2021) (0)
The Deletion of NHR1 Region of the AML1-ETO Protein Significantly Decreases Its Ability To Promote Proliferation and Self-Renewal of Early Hematopoietic Cells in Culture. (2006) (0)
TIP30 acts as a tumor suppressor in hepatocarcinogenesis (2004) (0)
C1-Tetrahydrofolate synthase stabilizes HIF-1a by disrupting the interaction with the von Hippel Lindau tumor suppressor gene product (2007) (0)
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF (2019) (0)
Medical News : Post-op treatment * % tor heart irregularity shows promise O Music : Gateway Festival Orchestra begins free summer concerts July 10 Washington People (2014) (0)
Biochemistry. In the article “The TRAP220 component of a thyroid hormone receptor-associated protein (TRAP) coac- tivator complex interacts directly with nuclear receptors in a ligand-dependent fashion” by (1998) (0)
DROSOPHILA TBP ASSOCIATED FACTORS DTAFII42/DTAFII62 HETEROTETRAMER (1996) (0)
Crystal structure of RAP74 C-terminal domain complexed with FCP1 C-terminal peptide (2003) (0)
Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1 (2018) (0)
Distinct Molecular Structures ofNuclear Class I,II, andIIIDNA-Dependent RNAPolymerases* (mouseplasmacytoma/Xenopus laevis/comparative electrophoretic analyses/common subunits) (1975) (0)
PAF1 and FACT cooperate with MLL-AF4 to drive enhancer activity in leukemia (2022) (0)
Recombinant 43-kDaUSF BindstoDNA andActivates Transcription ina MannerIndistinguishabl e from ThatofNatural 43/44-kDa USF (1991) (0)

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