Robert Hall Michell
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Molecular Biochemist
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Biology
Robert Hall Michell's Degrees
- Bachelors Biochemistry University of California, Berkeley
- PhD Molecular Biology Stanford University
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(Suggest an Edit or Addition)Robert Hall Michell's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Inositol phospholipids and cell surface receptor function. (1975) (2105)
- Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance (2008) (544)
- Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis (1997) (439)
- The polyphosphoinositide phosphodiesterase of erythrocyte membranes. (1981) (436)
- Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones. (1983) (406)
- Hormonal stimulation of phosphatidylinositol breakdown with particular reference to the hepatic effects of vasopressin. (1979) (395)
- The site of diphosphoinositide synthesis in rat liver. (1965) (382)
- The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questions. (1981) (370)
- The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane. (1982) (359)
- Inositol derivatives: evolution and functions (2008) (353)
- Svp1p defines a family of phosphatidylinositol 3,5‐bisphosphate effectors (2004) (315)
- Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. (2002) (306)
- Diacylglycerols and phosphatidates: which molecular species are intracellular messengers? (1998) (295)
- Inositol phospholipids in membrane function (1979) (246)
- Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions. (2006) (228)
- The distributions of some granule-associated enzymes in guinea-pig polymorphonuclear leucocytes. (1970) (226)
- Release of diacylglycerol-enriched vesicles from erythrocytes with increased intracellular [Ca2+] (1976) (217)
- Stepwise enzymatic dephosphorylation of inositol 1,4,5-trisphosphate to inositol in liver (1984) (211)
- The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae (1998) (203)
- Rapid accumulation of inositol phosphates in isolated rat superior cervical sympathetic ganglia exposed to V1-vasopressin and muscarinic cholinergic stimuli. (1984) (194)
- Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function. (2009) (188)
- Phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: lipids in search of a function. (1982) (182)
- A purified plasma membrane fraction isolated from rat liver under isotonic conditions. (1967) (165)
- Estrogenic alkylphenols induce cell death by inhibiting testis endoplasmic reticulum Ca(2+) pumps. (2000) (163)
- Hormone-stimulated metabolism of inositol lipids and its relationship to hepatic receptor function. (1981) (151)
- Similar effects of substance P and related peptides on salivation and on phosphatidylinositol turnover in rat salivary glands. (1980) (146)
- Inhibition of phosphatases and increased Ca2+ channel activity by inositol hexakisphosphate. (1997) (137)
- Why is phosphatidylinositol degraded in response to stimulation of certain receptors (1981) (136)
- Accumulation of 1,2-diacylglycerol in the plasma membrane may lead to echinocyte transformation of erythrocytes (1975) (135)
- Rapid transbilayer diffusion of 1,2-diacylglycerol and its relevance to control of membrane curvature (1978) (134)
- A vasopressin-like peptide in the mammalian sympathetic nervous system (1984) (132)
- Vac14 Controls PtdIns(3,5)P 2 Synthesis and Fab1-Dependent Protein Trafficking to the Multivesicular Body (2002) (132)
- A calcium-activated polyphosphoinositide phosphodiesterase in the plasma membrane of human and rabbit erythrocytes. (1978) (130)
- PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49. (2004) (125)
- Phosphatidylinositol metabolism in cells receiving extracellular stimulation (1973) (114)
- Recovery of membrane micro-vesicles from human erythrocytes stored for transfusion: a mechanism for the erythrocyte discocyte-to-spherocyte shape transformation. (1977) (113)
- Complementation Analysis in PtdInsPKinase-deficient Yeast Mutants Demonstrates ThatSchizosaccharomyces pombe and Murine Fab1p Homologues Are Phosphatidylinositol 3-Phosphate 5-Kinases* (1999) (111)
- A membrane-bound activity catalysing phosphatidylinositol breakdown to 1,2-diacylglycerol, D-myoinositol 1:2-cyclic phosphate an D-myoinositol 1-phosphate. Properties and subcellular distribution in rat cerebral cortex. (1973) (109)
- MEASUREMENT OF RATES OF PHAGOCYTOSIS (1969) (105)
- Phosphatidylinositol metabolism in rat hepatocytes stimulated by vasopressin. (1981) (103)
- Is phosphatidylinositol really out of the calcium gate? (1982) (101)
- Inositol lipid metabolism in dividing and differentiating cells. (1982) (100)
- Interleukin 4 activates human B lymphocytes via transient inositol lipid hydrolysis and delayed cyclic adenosine monophosphate generation (1990) (100)
- The opening of the inositol 1,4,5-trisphosphate-sensitive Ca2+ channel in rat cerebellum is inhibited by caffeine. (1992) (99)
- Membranes and Their Cellular Functions (1974) (98)
- Phosphatidylinositol metabolism in rat hepatocytes stimulated by glycogenolytic hormones. Effects of angiotensin, vasopressin, adrenaline, ionophore A23187 and calcium-ion deprivation. (1979) (96)
- Production of 1,2-diacylglycerol and phosphatidate in human erythrocytes treated with calcium ions and ionophore A23187. (1976) (90)
- Metabolism of D-myo-inositol 1,3,4,5-tetrakisphosphate by rat liver, including the synthesis of a novel isomer of myo-inositol tetrakisphosphate. (1987) (89)
- The possible involvement of phosphatidylinositol breakdown in the mechanism of stimulus-response coupling at receptors which control cell-surface calcium gates. (1977) (89)
- Breakdown of phosphatidylinositol provoked by muscarinic cholinergic stimulation of rat parotid-gland fragments. (1974) (87)
- Enhanced synthesis de novo of phosphatidylinositol in lymphocytes treated with cationic amphiphilic drugs. (1975) (86)
- Ca2+ and protein kinase C: Two synergistic cellular signals (1983) (84)
- Altered T lymphocyte signaling in rheumatoid arthritis (1995) (82)
- Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts. (1993) (82)
- Inositol phosphates: Profusion and confusion (1986) (79)
- The relationship of calcium to receptor-controlled stimulation of phosphatidylinositol turnover. Effects of acetylcholine, adrenaline, calcium ions, cinchocaine and a bivalent cation ionophore on rat parotid-gland fragments. (1975) (76)
- Complex changes in cellular inositol phosphate complement accompany transit through the cell cycle. (2004) (74)
- Pasteurella multocida toxin, a potent mitogen, increases inositol 1,4,5-trisphosphate and mobilizes Ca2+ in Swiss 3T3 cells. (1991) (70)
- The effects of thimerosal on calcium uptake and inositol 1,4,5-trisphosphate-induced calcium release in cerebellar microsomes. (1993) (69)
- Calcium ion-dependent diacylglycerol accumulation in erythrocytes is associated with microvesiculation but not with efflux of potassium ions. (1977) (69)
- Receptor occupancy dose—response curve suggests that phosphatidyl‐inositol breakdown may be intrinsic to the mechanism of the muscarinic cholinergic receptor (1976) (68)
- Stimulus-response coupling at alpha-adrenergic receptors. (1978) (68)
- Inositol lipids in cellular signalling mechanisms. (1992) (67)
- Cell differentiation and proliferation--simultaneous but independent? (2003) (67)
- Extraction of polyphosphoinositides with neutral and acidified solvents. A comparison of guinea-pig brain and liver, and measurements of rat liver inositol compounds which are resistant to extraction. (1970) (66)
- Stimulation of phosphatidylinositol turnover in various tissues by cholinergic and adrenergic agonists, by histamine and by caerulein. (1979) (66)
- The control by Ca2+ of the polyphosphoinositide phosphodiesterase and the Ca2+-pump ATPase in human erythrocytes. (1982) (63)
- Redistribution of protein kinase C during mitogenesis of human B lymphocytes. (1986) (62)
- Dephosphorylation of myo-inositol 1,4,5-trisphosphate and myo-inositol 1,3,4-triphosphate. (1987) (61)
- Multiple metabolic pools of phosphoinositides and phosphatidate in human erythrocytes incubated in a medium that permits rapid transmembrane exchange of phosphate. (1987) (61)
- Cell Proliferation and CD11b Expression Are Controlled Independently during HL60 Cell Differentiation Initiated by 1,25α-Dihydroxyvitamin D3 or All-trans-Retinoic Acid (2001) (61)
- Characteristics of rat liver phosphatidylinositol kinase and its presence in the plasma membrane. (1967) (61)
- Inositol hexakisphosphate in Schizosaccharomyces pombe: synthesis from Ins(1,4,5)P3 and osmotic regulation. (1998) (61)
- The redirection of glyceride and phospholipid synthesis by drugs including chlorpromazine, fenfluramine, Imipramine, mepyramine and local anaesthetics (1975) (60)
- Incorporation of phosphate into diphosphoinositide by subcellular fractions from liver. (1965) (59)
- Intracellular signaling pathways involved in the induction of apoptosis in immature thymic T lymphocytes. (1996) (58)
- Muscarinic cholinergic stimulation of phosphatidylinositol turnover in the longitudinal smooth muscle of guinea-pig ileum. (1976) (58)
- Phosphatidylinositol cleavage in lymphocytes. Requirement for calcium ions at a low concentration and effects of other cations. (1974) (58)
- Stimulation by acetylcholine of phosphatidylinositol labelling. Subcellular distribution in rat cerebral-cortex slices. (1972) (57)
- POST-RECEPTOR SIGNALLING PATHWAYS (1989) (57)
- The labelling of polyphosphoinositides with [32P]Pi and the accumulation of inositol phosphates in vasopressin-stimulated hepatocytes. (1986) (54)
- Changes in lipid metabolism and cell morphology following attack by phospholipase C (Clostridium perfringens) on red cells or lymphocytes. (1975) (53)
- Production of cyclic inositol phosphate in stimulated tissues. (1972) (52)
- Selective release of plasma-membrane enzymes from rat hepatocytes by a phosphatidylinositol-specific phospholipase C. (1980) (52)
- Potentiation of myeloid differentiation by anti-inflammatory agents, by steroids and by retinoic acid involves a single intracellular target, probably an enzyme of the aldoketoreductase family. (1996) (52)
- Evolution of the diverse biological roles of inositols. (2007) (51)
- Changes in the levels of inositol lipids and phosphates during the differentiation of HL60 promyelocytic cells towards neutrophils or monocytes (1991) (51)
- Phosphatidylinositol cleavage catalysed by the soluble fraction from lymphocytes. Activity at pH5.5 and pH7.0. (1974) (51)
- Polyphosphoinositide breakdown as the initiating reaction in receptor-stimulated inositol phospholipid metabolism. (1983) (50)
- Inositol and its derivatives: their evolution and functions. (2011) (49)
- Drug Redeployment to Kill Leukemia and Lymphoma Cells by Disrupting SCD1-Mediated Synthesis of Monounsaturated Fatty Acids. (2015) (48)
- Indomethacin potentiates the induction of HL60 differentiation to neutrophils, by retinoic acid and granulocyte colony-stimulating factor, and to monocytes, by vitamin D3. (1994) (48)
- Second‐messenger pathways involved in the regulation of survival in germinal‐centre B cells and in burkitt lymphoma lines (1992) (47)
- Hypo-osmotic Stress Activates Plc1p-dependent Phosphatidylinositol 4,5-Bisphosphate Hydrolysis and Inositol Hexakisphosphate Accumulation in Yeast* (2004) (46)
- Membrane protein segregation during release of microvesicles from human erythrocytes (1978) (46)
- Accumulation of inositol phosphates in sympathetic ganglia. Effects of depolarization and of amine and peptide neurotransmitters. (1985) (44)
- Effects of calcium-antagonistic drugs on the stimulation by carbamoylcholine and histamine of phosphatidylinositol turnover in longitudinal smooth muscle of guinea-pig ileum. (1976) (43)
- Stimulated inositol lipid metabolism: an introduction. (1982) (43)
- Rat testicular myoid cells express vasopressin receptors: receptor structure, signal transduction, and developmental regulation. (1995) (43)
- Inositol lipids: from an archaeal origin to phosphatidylinositol 3,5‐bisphosphate faults in human disease (2013) (42)
- Biochemistry: G-protein control of inositol phosphate hydrolysis (1986) (42)
- A possible metabolic explanation for drug‐induced phospholipidosis (1976) (41)
- Basolateral plasma membranes of intestinal epithelial cells. Identification by lactoperoxidase-catalysed iodination and isolation after density perturbation with digitonin. (1975) (40)
- The use of phospholipase c to detect structural changes in the membranes of human erythrocytes aged by storage. (1978) (39)
- Stimulation of phosphatidylinositol turnover by histamine, 5-hydroxytryptamine and adrenaline in the longitudinal smooth muscle of guinea pig ileum. (1976) (39)
- The intracellular distribution of inositol polyphosphates in HL60 promyeloid cells. (1994) (39)
- Inositol 1:2(cyclic),4,5-trisphosphate is not a major product of inositol phospholipid metabolism in vasopressin-stimulated WRK1 cells. (1988) (39)
- A comparison of the effects of phytohaemagglutinin and of calcium ionophore A23187 on the metabolism of glycerolipids in small lymphocytes. (1977) (38)
- Enhanced phosphatidylinositol labelling in rat parotid fragments exposed to alpha-adrenergic stimulation. (1974) (38)
- Partial purification and some properties of rat brain inositol 1,4,5-trisphosphate 3-kinase. (1988) (38)
- Turkey erythrocytes possess a membrane-associated inositol 1,4,5-trisphosphate 3-kinase that is activated by Ca2+ in the presence of calmodulin. (1987) (37)
- Inositol lipids in cell signalling. (1989) (36)
- Monocytically differentiating HL60 cells proliferate rapidly before they mature. (1999) (35)
- The sequential determination model of hematopoiesis. (2007) (35)
- Muscarinic cholinergic stimulation of phosphatidylinositol turnover in isolated rat superior cervical sympathetic ganglia (1976) (35)
- Celluar signalling: A second messenger function for inositol tetrakisphosphate (1986) (34)
- The multiplying roles of inositol lipids and phosphates in cell control processes. (1997) (34)
- Intracellular concentrations of inositol, glycerophosphoinositol and inositol pentakisphosphate increase during haemopoietic cell differentiation. (1994) (33)
- The biosynthesis of triphosphoinositide by rat brain in vitro (1966) (33)
- Up-regulation of steroid sulphatase activity in HL60 promyelocytic cells by retinoids and 1alpha,25-dihydroxyvitamin D3. (2001) (33)
- Novel inositol containing phospholipids and phosphates: their synthesis and possible new roles in cellular signalling (1993) (32)
- PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection (2018) (32)
- Oncogenic intelligence: Oncogenes and inositol lipids (1984) (32)
- Investigation of the relationship between cell-surface calcium-ion gating and phosphatidylinositol turnover by comparison of the effects of elevated extracellular potassium ion concentration on ileium smooth muscle and pancreas. (1976) (32)
- Analysis of the metabolic turnover of the individual phosphate groups of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate. Validation of novel analytical techniques by using 32P-labelled lipids from erythrocytes. (1984) (32)
- Synergism between diacylglycerols and calcium ionophore in the induction of human B cell proliferation mimics the inositol lipid polyphosphate breakdown signals induced by crosslinking surface immunoglobulin. (1985) (31)
- Permeability characteristics of erythrocyte ghosts prepared under isoionic conditions by a glycol-induced osmotic lysis. (1977) (31)
- Human erythrocyte membranes exhibit a cooperative calmodulin-dependent Ca2+-ATPase of high calcium sensitivity (1981) (31)
- HL60 cells halted in G1 or S phase differentiate normally. (2002) (30)
- Inositol 1,2,3-trisphosphate and inositol 1,2- and/or 2,3-bisphosphate are normal constituents of mammalian cells. (1995) (30)
- Variant cell lines from the human promyelocyte line HL60. (1982) (30)
- Hydrolysis of 1,2-diglyceride by membrane-associated lipase activity during phospholipase C treatment of membranes (1973) (29)
- The inositol phosphates in WRK1 rat mammary tumour cells. (1992) (29)
- Preparation of erythrocyte ghosts by a glycol-induced osmotic lysis under isoionic conditions. (1976) (28)
- A Combination of Calcium Ionophore and 12‐O‐Tetradecanoyl‐Phorbol‐13‐Acetate (TPA) Stimulates the Growth of Purified Resting B Cells (1985) (28)
- Synthesis and iron binding studies of myo-inositol 1,2,3-trisphosphate and (+/-)-myo-inositol 1,2-bisphosphate, and iron binding studies of all myo-inositol tetrakisphosphates. (1996) (28)
- Glycerylphosphorylcholine phosphodiesterase in rat liver. Subcellular distribution and localization in plasma membranes. (1972) (28)
- Second Messengers: Sphingolipid signalling (1994) (28)
- Production of 1,2-diacylglycerol in human erythrocyte membranes exposed to low concentrations of calcium ions. (1976) (27)
- Cholinergically stimulated phosphatidylinositol breakdown in parotid-gland fragments is independent of the ionic environment. (1976) (26)
- Modulation of the organization of erythrocyte membrane phospholipids by cytoplasmic ATP. The susceptibility of isoionic human erythrocytes ghosts to attack by detergents and phospholipase C. (1978) (25)
- Enhanced phosphatidylinositol breakdown as a calcium-indepepdnet response of rat parotid fragments to substance P. (1978) (25)
- A simple assay method for determination of the specific radioactivity of the gamma-phosphate group of 32P-labelled ATP. (1983) (25)
- A protein complex that regulates PtdIns(3,5)P2 levels (2009) (25)
- Do inositol supplements enhance phosphatidylinositol supply and thus support endoplasmic reticulum function? (2018) (24)
- Transfer of very low density lipoprotein from hen plasma into egg yolk (1974) (24)
- Studies of receptor-stimulated inositol lipid metabolism should focus upon measurements of inositol lipid breakdown. (1981) (24)
- Receptors and recognition (1978) (23)
- Inositol lipids: receptor-stimulated hydrolysis and cellular lipid pools. (1988) (23)
- Faculty Opinions recommendation of Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling. (2011) (22)
- How do receptors at the cell surface send signals to the cell interior? (1987) (22)
- Preferential localization of rat liver D-myo-inositol 1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase in bile-canalicular plasma membrane and 'late' endosomal vesicles. (1988) (21)
- Thyroid-stimulating hormone rapidly stimulates inositol polyphosphate formation in FRTL-5 thyrocytes without activating phosphoinositidase C. (1996) (21)
- A possible role for phosphatidylinositol breakdown in muscarinic cholinergic stimulus-response coupling. (1977) (21)
- Inositol lipids and phosphates. (1989) (21)
- Are polyphosphoinositides associated with glycophorin in human erythrocyte membranes? (1979) (20)
- The interrelationships of the inositol phosphates formed in vasopressin-stimulated WRK-1 rat mammary tumour cells. (1992) (20)
- Differences in the enzymic, polypeptide, glycopeptide, glycolipid and phospholipid compositions of plasma membranes from the two surfaces of intestinal epithelial cells. (1975) (19)
- Cell proliferation and CD11b expression are controlled independently during HL60 cell differentiation initiated by 1,25 alpha-dihydroxyvitamin D(3) or all-trans-retinoic acid. (2001) (19)
- Inositol lipid breakdown as a step in alpha-adrenergic stimulus-response coupling. (1985) (18)
- Malayan tin tailings - prospects of rehabilitation. (1957) (18)
- Inositol cyclic phosphate as a product of phosphatidylinositol breakdown by phospholipase C (Bacillus cereus) (1975) (18)
- The unknown meaning of receptor-stimulated inositol lipid metabolism (1982) (18)
- Inositol lipid-mediated signalling in response to endothelin and ATP in the mammalian testis (1995) (18)
- Regulation of neurite outgrowth from differentiated human neuroepithelial cells: a comparison of the activities of prothrombin and thrombin. (1995) (17)
- Simultaneous oscillations of cytoplasmic free Ca2+ concentration and Ins(1,4,5)P3 concentration in mouse pancreatic beta-cells. (1994) (17)
- The role of phosphatidylinositol 4,5 bisphosphate breakdown in cell-surface receptor activation. (1984) (17)
- Phosphatidylinositol 4,5‐bisphosphate hydrolysis accompanies T cell receptor‐induced apoptosis of murine thymocytes within the thymus (1995) (16)
- A salt-activated inositol 1, 3, 4, 5-tetrakisphosphate 3-phosphatase at the inner surface of the human erythrocyte membrane (1991) (16)
- Determination of the steady-state turnover rates of the metabolically active pools of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in human erythrocytes. (1989) (16)
- The lethal oxidase of leucocytes (1983) (15)
- First came the link between phosphoinositides and Ca2+ signalling, and then a deluge of other phosphoinositide functions. (2009) (15)
- The pathway of myo-inositol 1,3,4-trisphosphate dephosphorylation in liver. (1987) (15)
- Is vasopressin-stimulated inositol lipid breakdown intrinsic to the mechanism of Ca2+-mobilization at V1 vasopressin receptors? (1983) (14)
- Morton Medal Lecture. New insights into the roles of phosphoinositides and inositol polyphosphates in yeast. (2001) (14)
- Inositol lipids and phosphates in the regulation of the growth and differentiation of haemopoietic and other cells. (1990) (14)
- The use of cells doubly labelled with [14C]inositol and [3H]inositol to search for a hormone-sensitive inositol lipid pool with atypically rapid metabolic turnover. (1989) (13)
- Bovine testis and human erythrocytes contain different subtypes of membrane-associated Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphomonoesterases. (1994) (13)
- Continuing professional development (1989) (13)
- Editors are meant to be judges, not postmen (2003) (13)
- Inositol trisphosphate and tetrakisphosphate phosphomonoesterases of rat liver. (1987) (12)
- The possible role of lipids in control of membrane fusion during secretion. (1979) (12)
- Chapter 1 Isolation, composition and general structure of membranes (1981) (12)
- Inositol phosphates in growing and differentiating HL60 cells (1988) (12)
- Hormone action at membranes (1984) (12)
- Changes in inositol transport during DMSO-induced differentiation of HL60 cells towards neutrophils. (1991) (12)
- Elevation of intracellular calcium ion concentration provokes production of 1,2-diacylglycerol and phosphatidate in human erythrocytes. (1975) (12)
- Inositol lipids and phosphates in growing, stimulated and differentiating cells. (1989) (11)
- G-protein control of inositol phosphate hydrolysis. (1986) (11)
- Early steps along the road to inositol-lipid-based signalling. (1995) (11)
- Inhibition by glucocorticoid and staurosporine of IL‐4‐dependent CD23 production in B lymphocytes is reversed on engaging CD40 (1993) (11)
- Stimulation of the breakdown and resynthesis of of phosphatidylinositol in rat hepatocytes by angiotensin, vasopressin and adrenaline. (1978) (11)
- Calcium uptake by intracellular compartments in permeabilised enterocytes. Effect of inositol 1,4,5 trisphosphate. (1986) (10)
- Effects of acetylcholine on incorporation of [14C]glucose into phosphatidylinositol and on phosphatidylinositol breakdown in subcellular fractions from cerebral cortex (1974) (10)
- Hormone-mediated inositol lipid breakdown in hepatocytes and WRK1 cells: relationship to receptor function. (1985) (10)
- Phosphatidylinositol kinase activity in Saccharomyces cerevisiae. (1972) (10)
- Pleiotypic responses: regulation by programmable messengers or by multiple receptors? (1986) (10)
- Building bodies (1992) (10)
- Phosphatidylinositol 3,5-bisphosphate: a novel lipid that links stress responses to membrane trafficking events. (1999) (9)
- Mitogen-induced phosphorylation of human B-lymphocyte proteins. Relationship to protein kinase C activation. (1989) (9)
- Inositol Phosphates: A Remarkably Versatile Enzyme (2002) (9)
- Levels of inositol metabolites within normal myeloid blast cells and changes during their differentiation towards monocytes (1992) (9)
- Inositol 1,2,3-trisphosphate is a product of InsP6 dephosphorylation in WRK-1 rat mammary epithelial cells and exhibits transient concentration changes during the cell cycle. (1995) (9)
- Do cells contain discrete pools of inositol lipids that are coupled to receptor activation? (1989) (9)
- Biochemical differentiation of the plasma membrane of the intestinal epithelial cell. (1976) (8)
- Dephosphorylation of 1D-myo-inositol 1,4-bisphosphate in rat liver. (1988) (8)
- Versatility and nuances of the architecture of haematopoiesis - Implications for the nature of leukaemia. (2012) (8)
- A second messenger function for inositol tetrakisphosphate. (1986) (8)
- Membranes and their cellular functions 3rd edition (1984) (8)
- Regulation of the interleukin 4 signal in human B-lymphocytes. (1991) (8)
- Two sites for Ca2+ control in one Ca2+ pump (1982) (8)
- Significance of minor glycerolipids in membrane structure and function. (1976) (8)
- Apparent variations in the activation characteristics of human erythrocyte membrane Ca2+-pump ATPase may be caused by variable membrane permeability (1981) (8)
- A link between lithium, lipids and receptors? (1982) (7)
- Nuclear PIPs (1992) (7)
- The relationship between Ca2+-mediated polyphosphoinositide phosphodiesterase activity, 1, 2-diacylglycerol accumulation, and microvesiculation in erythrocytes. (1979) (7)
- Inhibition of porcine brain inositol 1,3,4-trisphosphate kinase by inositol polyphosphates, other polyol phosphates, polyanions and polycations. (1994) (7)
- 1D-myo-inositol 1,4,5-trisphosphate dephosphorylation by rat enterocytes involves an intracellular 5-phosphatase and non-specific phosphatase activity at the cell surface. (1988) (7)
- How may advances in oral rehydration therapy for animals benefit children (2004) (7)
- Inositol lipids and phosphates in erythrocytes and HL60 cells. (1988) (6)
- Measurement of the metabolic turnover of the 4- and 5-phosphates of phosphatidylinositol 4,5-bisphosphate in erythrocytes (1982) (6)
- Faculty Opinions recommendation of VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse. (2008) (6)
- What could Dr Finlay and Mr Herriot learn from each other? (2005) (6)
- Lipase activity against 1,2-diglyceride in rat erythrocyte membranes. (1971) (6)
- Oncogenes and inositol lipids. (1984) (6)
- Stimulation of tyrosine phosphorylation without inositol lipid hydrolysis in human B lymphocytes on engaging CD72 (1993) (6)
- The versatility of haematopoietic stem cells: implications for leukaemia (2010) (6)
- Molecular events following activation of muscarinic receptors: the role of inositol phospholipids. (1982) (6)
- Inositol lipid-dependent functions in Saccharomyces cerevisiae: analysis of phosphatidylinositol phosphates. (2009) (5)
- Metabolism of phosphatidate at the plasma membrane. (1977) (5)
- Diacylglycerols and phosphatidates: which molecular species are (1998) (5)
- Inositol lipids and phosphates in the proliferation and differentiation of lymphocytes and myeloid cells. (1992) (4)
- Dephosphorylation of D-myo-inositol-1,4,5-trisphosphate in testes. (1991) (4)
- Widely Accepted Modern Views of Cell Structure are Fundamentally Correct: A Reply to Hillman and Sartory. (1982) (4)
- Inositol tetrakisphosphates in WRK-1 cells (1988) (4)
- A search for a hormone-sensitive inositol lipid pool in WRK 1 mammary tumour cells (1989) (4)
- Inositol 1:2-Cyclic Phosphate in Tissues (1973) (4)
- Faculty Opinions recommendation of SETH1 and SETH2, two components of the glycosylphosphatidylinositol anchor biosynthetic pathway, are required for pollen germination and tube growth in Arabidopsis. (2004) (4)
- A possible role for 1,2-diacylglycerol in fusion of erythrocytes by Sendai virus. (1976) (4)
- Protein phosphorylation events and changes in inositol metabolism during HL60 cell differentiation. (1991) (3)
- Cellular recognition (1978) (3)
- A comparison of haemoglobin-free human erythrocyte "ghosts" prepared under isoionic and hypoionic conditions [proceedings]. (1977) (3)
- Why shouldn't children benefit from oral rehydration solutions for calves? (2005) (3)
- Revalidation and virtual patients: a vision of the future? (2002) (3)
- Inositol Lipids in Cellular Signaling (1987) (3)
- Receptor-Controlled Phosphatidylinositol 4,5-Bisphosphate Hydrolysis in the Control of Rapid Receptor-Mediated Cellular Responses and of Cellular Proliferation (1985) (3)
- Inositol lipid breakdown and muscarinic mechanisms (1984) (3)
- Inositol lipids and transmembrane signalling : proceedings of a Royal Society discussion meeting held on 2 and 3 December 1987 (1988) (3)
- Inositol lipids and phosphates in the differentiation of blood cells. (1990) (3)
- Oedema in cattle - causes and clinical implications (1996) (3)
- The role of inositol lipid hydrolysis in the selection of immature thymocytes. (1991) (3)
- Cell regulation: editorial overview (1989) (2)
- The inositol 1,4,5-trisphosphate 6-kinase of Schizosaccharomyces pombe. (1997) (2)
- Ca2+-DEPENDENT POLYPHOSPHOINOSITIDE (PPI) BREAKDOWN IN STIMULATED RAT HEPATOCYTES (1981) (2)
- Mike Wakelam: an appreciation (2020) (2)
- Phosphodiesterase-catalysed breakdown of phosphatidylinositol 4,5-bisphosphate initiates receptor-stimulated inositol lipid metabolism (1984) (2)
- A Comment on Nomenclature and Abbreviations (1988) (2)
- The involvement of inositol lipids and phosphates in signalling in the fission yeast Schizosaccharomyces pombe. (1995) (2)
- New direction for health care regulation? (2005) (2)
- Localisation of bradykinin-like immunoreactivity and modulation of bradykinin-evoked phospholipase D activity by 17 beta-oestradiol in human endometrium. (1995) (2)
- Inositol lipid breakdown in receptor-mediated responses of sympathetic ganglia and sympathetically innervated tissues (1985) (2)
- A simple assay for the polyphosphoinositide phosphodiesterase of the human erythrocyte membrane [proceedings]. (1980) (2)
- Transfer of Very-Low-Density Lipoprotein from Hen Plasma into Egg Yolk (1974) (2)
- The relationship between calcium ion gates and the stimulation of phosphatidylinositol turnover. (1977) (2)
- The role of inositol transport in cellular differentiation. (1991) (1)
- Inositol lipid-mediated signalling in the nervous system (1986) (1)
- Endothelin-1 stimulates inositol phosphate production in rat testis. (1993) (1)
- Inhibition of inositol 1,3,4-trisphosphate 5/6-kinase by amino acid modifying agents. (1993) (1)
- THE INFLUENCE OF INTRACELLULAR Ca 2+ ON THE METABOLISM OF INOSITOL PHOSPHOLIPIDS IN LYMPHOCYTES AND ERYTHROCYTES (1978) (1)
- THE RELATIONSHIP BETWEEN Ca2+-STIMULATED POLYPHOSPHOINOSITIDE BREAKDOWN AND THE Ca2+-PUMP ATPase IN HUMAN ERYTHROCYTE MEMBRANES (1981) (1)
- Agonist regulation of α-adrenergic receptor numbers (1979) (1)
- Metabolic pooling of inositol lipids in mature erythrocytes and in hormone-stimulated mammalian cells. (1987) (1)
- In a poetic vein (2012) (1)
- The intracellular distribution of inositol polyphosphates. (1993) (1)
- Science spending (1985) (1)
- DEFRA's proposals on equine dentistry. (2001) (1)
- Obituary: Mabel R. Hokin (1924–2003) (2003) (1)
- FMD and the contiguous cull. (2004) (1)
- Rheumatoid arthritis, then and now (2022) (1)
- Polyphosphoinositides in isolated preparations of human erythrocyte membrane glycophorin [proceedings]. (1979) (1)
- Renal disease and canine hypertension (2010) (1)
- Clinical research and antimicrobial resistance. (2000) (1)
- Ca2+ uptake by intracellular compartments in isolated enterocytes: effect of inositol 1,4,5-trisphosphate (1986) (1)
- Regulation of paraprofessionals. (2004) (0)
- The buck stops with government (1990) (0)
- Current understanding of intracellular signalling pathways - Introduction (1996) (0)
- FMD and the contiguous cull (2005) (0)
- 'Animals under our care'--whose care, and for how long? (1998) (0)
- Dephosphorylation of myo -inositol 1,4,5-trisphosphate (1985) (0)
- FMD control strategies. (2003) (0)
- Role of veterinary nurses. (2001) (0)
- Production of 1,2-diacylglycerol in human erythrocyte 'ghosts' exposed to very low calcium ion concentrations. (1976) (0)
- Relative risk. (1996) (0)
- Membranes and their Cellular Function (2009) (0)
- Faculty Opinions recommendation of The PI(3,5)P2 and PI(4,5)P2 interactomes. (2009) (0)
- Mluscarinic Cholinergic Stimulation of Phosphatidylinositol Turnover in the Longitudinal Smooth Muscle of Guinea-Pig Ileum (2005) (0)
- Canine longevity. (2000) (0)
- Veterinary research. (1997) (0)
- Receptor regulation: edited by R. J. Lefkowitz, Chapman and Hall, 1981. £25 (viii + 253 pages) ISBN 0 412 15930 9 (1982) (0)
- Inositol 1,4,5-Triphosphate and Inositol 1,3,4,5-Tetrakisphosphate: Functions, Metabolism and Interconversion (1991) (0)
- Steroid sulphatase activity is up-regulated during retinoid and vitamin D3-induced differentiation of HL60 cells (2000) (0)
- Faculty Opinions recommendation of A novel biosynthetic pathway of archaetidyl-myo-inositol via archaetidyl-myo-inositol phosphate from CDP-archaeol and D-glucose 6-phosphate in methanoarchaeon Methanothermobacter thermautotrophicus cells. (2009) (0)
- Faculty Opinions recommendation of Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry. (2011) (0)
- ‘Primary’ and ‘secondary’ hormones — is there a sharp distinction? (1979) (0)
- Undergraduate curriculum in veterinary schools (2005) (0)
- Oral rehydration: under- or over-rated? (1999) (0)
- liver, including thesynthesis ofa novel isomer ofmyo-inositol tetrakisphosphate (1987) (0)
- New rules on medicines (1995) (0)
- The reliability of biomedical science: A case history of a maturing experimental field (2022) (0)
- Student numbers and university funding. (1997) (0)
- University costs and graduate remuneration (2014) (0)
- Faculty Opinions recommendation of A study of archaeal enzymes involved in polar lipid synthesis linking amino acid sequence information, genomic contexts and lipid composition. (2005) (0)
- New rules on medicines (1995) (0)
- Identification of phosphoinositide-binding proteins by using phosphoinositide-coupled affinity matrices (2001) (0)
- A MULTI-COPY SUPPRESSOR OF A TEMPERATURE-SENSITIVE ALLELE OF THE S. cerevisiae TYPE III PHOSPHATIDYLINOSITOL PHOSPHATE KINASE Fab1p (2000) (0)
- FMD inquiry. (2001) (0)
- Identification and isolation of basolateral plasma membranes from intestinal epithelial cell sheets. (1975) (0)
- Government and the cascade. (1996) (0)
- More phosphoinositide cookery (1998) (0)
- Stimulation by Acetylcholine of Phosphatidyilnositol Labelling SUBCELLULAR DISTRIBUTION IN RAT CEREBRAL-CORTEX SLICES (2005) (0)
- Proteins related to the red-cell cytoskeleton in non-erythroid cells (1982) (0)
- Calf diarrhoea quiz (1991) (0)
- Therapeutic claims for unlicensed products. (1997) (0)
- Faculty Opinions recommendation of Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules. (2006) (0)
- In a poetic vein (2012) (0)
- 'Omnicompetent' graduates. (1999) (0)
- Synthesis and Iron Binding Studies of myo-Inositol 1,2,3-Trisphosphate and (.+-.)-myo-Inositol 1,2-Bisphosphate, and Iron Binding Studies of All myo-Inositol Tetrakisphosphates. (2010) (0)
- INOSITOL LIPID METABOLISM IN RECEPTOR-STIMULATED AND DEPOLARIZED SYMPATHETIC GANGLIA AND ADRENAL GLANDS (1986) (0)
- THE SOLDIER'S HEART AND THE STRAINED HEART (1916) (0)
- Phosphatidylinositol(3,5)bisphosphate: a novel Inositol lipid linking stress responses to membrane trafficking in yeast (1999) (0)
- Martin Geoffrey Low. 27 July 1950—6 August 2013 (2018) (0)
- Faculty Opinions recommendation of Structure of HDAC3 bound to co-repressor and inositol tetraphosphate. (2012) (0)
- Agonist regulation of alpha-adrenergic receptor numbers. (1979) (0)
- FMD control strategies. (2003) (0)
- Phosphatidylinositol turnover stimulated by acetylcholine: subcellular distribution in rat cerebral cortex. (1972) (0)
- Agriculture at sea. (1999) (0)
- MgATP2- and the molecular organization of erythrocyte membranes [proceedings]. (1978) (0)
- Centre for tropical veterinary medicine. (2002) (0)
- The continuing history of the remarkable tablets of stone (2015) (0)
- Role of glutamine in oral rehydration of calves (2016) (0)
- Effects of alkylating antagonists on the stimulated turnover of phosphatidylinositol produced by a variety of calcium-mobilising receptor systems (1980) (0)
- Society for Veterinary Clinical Research. (2000) (0)
- Methods in inositide research (1992) (0)
- Transport processes through biological membranes (1978) (0)
- MAMMALIAN PtdInsP KINASES: ANALYSIS OF THEIR PtdInsP2 SPECIFICITY IN VIVO BY EXPRESSION IN FAB1-DELETED YEAST (1999) (0)
- Analytical methods to quantify phosphoinositide turnover and related reactions (1986) (0)
- Faculty Opinions recommendation of Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles. (2004) (0)
- Altered protein tyrosine phosphorylation in rheumatoid T cells which is mimicked by hydrogen peroxide. (1997) (0)
- Faculty Opinions recommendation of Evolution of the biosynthesis of di-myo-inositol phosphate, a marker of adaptation to hot marine environments. (2012) (0)
- Calmodulin and cell functions: edited by D. M. Watterson and F. F. Vincenzi, New York Academy of Sciences, 1981. $86.00 (xii + 446 pages) ISBN 0 89766 101 X (1982) (0)
- Hypertension and renal function in dogs (2008) (0)
- Faculty Opinions recommendation of Ca2+ entry through plasma membrane IP3 receptors. (2006) (0)
- Faculty Opinions recommendation of Ent5p is required with Ent3p and Vps27p for ubiquitin-dependent protein sorting into the multivesicular body. (2004) (0)
- Comparative medicine (2012) (0)
- Handbook of experimental pharmacology, vol. 58/1. Cyclic nucleotides, part I, biochemistry (1983) (0)
- Glycerylphosphorylcholine phosphodiesterase in rat liver plasma membranes. (1972) (0)
- Receptor-mediated inositol lipid breakdown provokes Ca2+-mobilization and protein phosphorylation in stimulated cells (1984) (0)
- Transcription enhancer sequences: a novel regulatory element (1982) (0)
- FMD inquiries. (2002) (0)
- FMD control strategies. (2002) (0)
- Dealing with Brexit (2016) (0)
- Teaching at the Centre for Tropical Veterinary Medicine. (2002) (0)
- Recommended reading (1977) (0)
- THE SOLDIER'S HEART (1915) (0)
- RCVS guide to student behaviour (2014) (0)
- 36P PROCEEDINGS OF THE BIOCHEMICAL SOCIETY Glycerylphosphorylcholine Phosphodiesterase in Rat Liver Plasma Membranes (2005) (0)
- Metabolism of Ins(1,3,4)P3 by Rat Liver Homogenates (1989) (0)
- FMD control strategies. (2001) (0)
- Veterinary voice (2008) (0)
- Biosynthesis of diphosphoinositide (1965) (0)
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