R. Obert Huber

R. Obert Huber's AcademicInfluence.com Rankings

R. Obert Huber

Physics

#1520

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#2329

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Biophysics

#29

World Rank

#31

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Physics

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R. Obert Huber's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution (1985) (2726)
Accurate Bond and Angle Parameters for X-ray Protein Structure Refinement (1991) (2491)
Structure of 20S proteasome from yeast at 2.4Å resolution (1997) (2245)
X-ray structure analysis of a membrane protein complex. Electron density map at 3 A resolution and a model of the chromophores of the photosynthetic reaction center from Rhodopseudomonas viridis. (1984) (1597)
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. (1995) (1506)
The complete genome of the hyperthermophilic bacterium Aquifex aeolicus (1998) (1091)
Natural protein proteinase inhibitors and their interaction with proteinases. (1992) (979)
A gated channel into the proteasome core particle (2000) (808)
The refined 1.9 A crystal structure of human alpha‐thrombin: interaction with D‐Phe‐Pro‐Arg chloromethylketone and significance of the Tyr‐Pro‐Pro‐Trp insertion segment. (1989) (747)
Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function. (1984) (665)
Proteasome from Thermoplasma acidophilum: a threonine protease. (1995) (650)
The structure of a complex of recombinant hirudin and human alpha-thrombin. (1990) (646)
The 3.2-Å crystal structure of the human IgG1 Fc fragment–FcγRIII complex (2000) (630)
Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity. (2003) (630)
Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1 (1997) (606)
Structural basis of the activation and action of trypsin (1978) (599)
The refined 2.15 A X‐ray crystal structure of human liver cathepsin B: the structural basis for its specificity. (1991) (547)
The 2.0 A X‐ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases. (1988) (530)
The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors (1983) (507)
Thermotoga maritima sp. nov. represents a new genus of unique extremely thermophilic eubacteria growing up to 90°C (1986) (501)
Handbook of metalloproteins (2006) (499)
Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. II. Crystallographic refinement at 1.9 A resolution. (1974) (488)
Hyperthermophilic archaea are thriving in deep North Sea and Alaskan oil reservoirs (1993) (472)
The refined 2.4 A X‐ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction. (1990) (450)
Aquifex pyrophilus gen. nov. sp. nov., Represents a Novel Group of Marine Hyperthermophilic Hydrogen-Oxidizing Bacteria (1992) (426)
Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 A resolution. (1984) (421)
Structure and mechanism of the aberrant ba3‐cytochrome c oxidase from Thermus thermophilus (2000) (414)
Crystallographic refinement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 A and 1.0 A resolution. (1980) (409)
HTRA proteases: regulated proteolysis in protein quality control (2011) (409)
Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine (2002) (407)
Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. Crystal structure determination and stereochemistry of the contact region. (1973) (406)
Crystal Structure of the Thermosome, the Archaeal Chaperonin and Homolog of CCT (1998) (405)
The blue oxidases, ascorbate oxidase, laccase and ceruloplasmin. Modelling and structural relationships. (1990) (402)
X-ray crystal structures of cytosolic glutathione S-transferases. Implications for protein architecture, substrate recognition and catalytic function. (1994) (386)
Crystal Structure of a Carbon Monoxide Dehydrogenase Reveals a [Ni-4Fe-5S] Cluster (2001) (384)
Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5.5 and pH 9.0. A pH-induced conformational transition involves a peptide bond flip. (1991) (379)
Crystallographic structure studies of an IgG molecule and an Fc fragment (1976) (373)
The genome sequence of the extreme thermophile Thermus thermophilus (2004) (372)
Refined crystal structure of ascorbate oxidase at 1.9 A resolution. (1992) (366)
The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium. (2000) (363)
Crystal Structure of the Xanthine Oxidase-Related Aldehyde Oxido-Reductase from D. gigas (1995) (362)
Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes. (1993) (355)
Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1. (1998) (355)
Phosphotransferase and substrate binding mechanism of the cAMP‐dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5‐24). (1993) (350)
Structure of human des(1-45) factor Xa at 2.2 A resolution. (1993) (347)
Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme. (1998) (342)
The crystal and molecular structure of human annexin V, an anticoagulant protein that binds to calcium and membranes. (1990) (340)
X-ray crystal structure of the blue oxidase ascorbate oxidase from zucchini. Analysis of the polypeptide fold and a model of the copper sites and ligands. (1989) (328)
Refined structure of the hirudin-thrombin complex. (1991) (325)
X-ray crystallographic structure of the light-harvesting biliprotein C-phycocyanin from the thermophilic cyanobacterium Mastigocladus laminosus and its resemblance to globin structures. (1985) (317)
The structures of HslU and the ATP-dependent protease HslU–HslV (2000) (315)
Structure of bovine pancreatic trypsin inhibitor (1984) (315)
Structural basis for the anticoagulant activity of the thrombin–thrombomodulin complex (2000) (305)
Crystal structure of calcium-depleted Bacillus licheniformis alpha-amylase at 2.2 A resolution. (1995) (304)
Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer. (1994) (303)
A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism (2008) (293)
Pyrobaculum aerophilum sp. nov., a novel nitrate-reducing hyperthermophilic archaeum (1993) (291)
Structure of cytochrome c nitrite reductase (1999) (286)
The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. The refined crystal structures of the bovine trypsinogen-pancreatic trypsin inhibitor complex and of its ternary complex with Ile-Val at 1.9 A resolution. (1978) (283)
The X‐ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity. (1994) (281)
The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study. (1999) (279)
The three‐dimensional structure of class pi glutathione S‐transferase in complex with glutathione sulfonate at 2.3 A resolution. (1991) (278)
The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism (2003) (278)
Refined three-dimensional structures of two cyanobacterial C-phycocyanins at 2.1 and 2.5 A resolution. A common principle of phycobilin-protein interaction. (1987) (275)
Crystal structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of beta-lactone ring opening and a mechanism for irreversible binding. (2006) (275)
Transcriptional silencing and longevity protein Sir 2 is an NAD-dependent histone deacetylase (272)
Catalysis at a dinuclear [CuSMo(O)OH] cluster in a CO dehydrogenase resolved at 1.1-Å resolution (2002) (272)
Structural basis of the endoproteinase-protein inhibitor interaction. (2000) (272)
The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex. (2000) (271)
Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases (1992) (270)
Structural homology of reaction centers from Rhodopseudomonas sphaeroides and Rhodopseudomonas viridis as determined by x-ray diffraction. (1986) (267)
Contribution of Proteasomal β-Subunits to the Cleavage of Peptide Substrates Analyzed with Yeast Mutants* (1998) (263)
Crystal Structures of Catalytic Subunit of cAMP-dependent Protein Kinase in Complex with Isoquinolinesulfonyl Protein Kinase Inhibitors H7, H8, and H89 (1996) (262)
Crystal Structure of Epoxomicin:20S Proteasome reveals a molecular basis for selectivity of alpha,beta-Epoxyketone Proteasome Inhibitors (2000) (261)
X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B. (1995) (258)
X‐ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor. (1986) (245)
Mechanism of the six-electron reduction of nitrite to ammonia by cytochrome c nitrite reductase. (2002) (242)
A structural basis of light energy and electron transfer in biology (1989) (240)
Human β-tryptase is a ring-like tetramer with active sites facing a central pore (1998) (239)
Crystal structures of the membrane-binding C2 domain of human coagulation factor V (1999) (238)
The molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-A resolution. (1975) (236)
Crystal structure of the first dissimilatory nitrate reductase at 1.9 A solved by MAD methods. (1999) (235)
Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation (2003) (228)
Methanopyrus kandleri, gen. and sp. nov. represents a novel group of hyperthermophilic methanogens, growing at 110°C (1991) (225)
Activation of Bacillus licheniformis alpha-amylase through a disorder-->order transition of the substrate-binding site mediated by a calcium-sodium-calcium metal triad. (1998) (224)
Crystal structure analysis and refinement at 2.5 A of hexameric C-phycocyanin from the cyanobacterium Agmenellum quadruplicatum. The molecular model and its implications for light-harvesting. (1986) (219)
Three-dimensional structure of class pi glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 A resolution. (1992) (219)
Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. (1999) (219)
Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis (2004) (215)
Isolation of a hyperthermophilic archaeum predicted by in situ RNA analysis (1995) (214)
A novel group of abyssal methanogenic archaebacteria (Methanopyrus) growing at 110 °C (1989) (213)
The calcium binding sites in human annexin V by crystal structure analysis at 2.0 A resolution Implications for membrane binding and calcium channel activity (1990) (212)
Crystal and molecular structure of human annexin V after refinement. Implications for structure, membrane binding and ion channel formation of the annexin family of proteins. (1992) (210)
The 2.8 A crystal structure of Gla‐domainless activated protein C. (1996) (209)
Structure of the stapled p53 peptide bound to Mdm2. (2012) (207)
Respiration of arsenate and selenate by hyperthermophilic archaea. (2000) (206)
Crystal structure and mechanism of CO dehydrogenase, a molybdo iron-sulfur flavoprotein containing S-selanylcysteine. (1999) (204)
Isolation, crystallization, crystal structure analysis and refinement of constitutive C-phycocyanin from the chromatically adapting cyanobacterium Fremyella diplosiphon at 1.66 A resolution. (1991) (204)
Crystal structure of bovine trypsinogen at 1-8 A resolution. II. Crystallographic refinement, refined crystal structure and comparison with bovine trypsin. (1977) (204)
Molecular structure of the bilin binding protein (BBP) from Pieris brassicae after refinement at 2.0 A resolution. (1987) (203)
Crystal and molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI. (1974) (202)
X-ray Structure of Active Site-inhibited Clotting Factor Xa (1996) (201)
A functional Ni-Ni-[4Fe-4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans. (2004) (198)
On the disordered activation domain in trypsinogen: chemical labelling and low‐temperature crystallography (1982) (196)
Crystal structure of phage P22 tailspike protein complexed with Salmonella sp. O-antigen receptors. (1996) (195)
Molecular Machines for Protein Degradation (2005) (195)
Isolation, crystallization, crystal structure analysis and refinement of allophycocyanin from the cyanobacterium Spirulina platensis at 2.3 A resolution. (1995) (192)
Crystal structure of dimethyl sulfoxide reductase from Rhodobacter capsulatus at 1.88 A resolution. (1996) (192)
Detergent structure in crystals of a bacterial photosynthetic reaction centre (1989) (192)
Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach. (2004) (190)
Comparison of two highly refined structures of bovine pancreatic trypsin inhibitor. (1987) (189)
Three-dimensional structure of glutathione S-transferase from Arabidopsis thaliana at 2.2 A resolution: structural characterization of herbicide-conjugating plant glutathione S-transferases and a novel active site architecture. (1996) (189)
The 2.5 A X‐ray crystal structure of the acid‐stable proteinase inhibitor from human mucous secretions analysed in its complex with bovine alpha‐chymotrypsin. (1988) (186)
The crystal structure of the proprotein processing proteinase furin explains its stringent specificity (2003) (186)
Functional significance of flexibility in proteins (1982) (186)
Thermocrinis ruber gen. nov., sp. nov., a Pink-Filament-Forming Hyperthermophilic Bacterium Isolated from Yellowstone National Park (1998) (186)
Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution. (1985) (185)
The interaction of thrombin with fibrinogen. A structural basis for its specificity. (1992) (185)
The ornithodorin‐thrombin crystal structure, a key to the TAP enigma? (1996) (185)
Substrate access and processing by the 20S proteasome core particle. (2003) (184)
Signature Lipids and Stable Carbon Isotope Analyses of Octopus Spring Hyperthermophilic Communities Compared with Those ofAquificales Representatives (2001) (182)
Crystal structure of heat shock locus V (HslV) from Escherichia coli. (1997) (181)
Expansion of the genetic code enables design of a novel "gold" class of green fluorescent proteins. (2003) (179)
The structures of HsIU and the ATP-dependent protease HsIU-HsIV. (2000) (177)
Novel 16S rRNA gene sequences retrieved from highly saline brine sediments of Kebrit Deep, Red Sea (1999) (173)
A structure-based catalytic mechanism for the xanthine oxidase family of molybdenum enzymes. (1996) (171)
Structural transition of α1‐antitrypsin by a peptide sequentially similar to β‐strand s4A (1990) (170)
Three-dimensional structure of the complex between pancreatic secretory trypsin inhibitor (Kazal type) and trypsinogen at 1.8 A resolution. Structure solution, crystallographic refinement and preliminary structural interpretation. (1982) (169)
Crystal structure of the 20 S proteasome:TMC-95A complex: a non-covalent proteasome inhibitor. (2001) (168)
The crystal structure of the proprotein processing proteinase furin explains its stringent specificity (2003) (168)
Crystal structure determination, refinement and the molecular model of the alpha-amylase inhibitor Hoe-467A. (1986) (167)
Tachylectin‐2: crystal structure of a specific GlcNAc/GalNAc‐binding lectin involved in the innate immunity host defense of the Japanese horseshoe crab Tachypleus tridentatus (1999) (166)
Cytochrome c Nitrite Reductase from Wolinella succinogenes (2000) (165)
Crystal structure of gingipain R: an Arg‐specific bacterial cysteine proteinase with a caspase‐like fold (1999) (164)
Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin. (1995) (164)
The refined 2.0 Å X‐ray crystal structure of the complex formed between bovine β‐trypsin and CMTI‐I, a trypsin inhibitor from squash seeds (Cucurbita maxima) Topological similarity of the squash seed inhibitors with the carboxypeptidase A inhibitor from potatoes (1989) (163)
Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA (2000) (161)
Organic solutes in hyperthermophilic archaea (1997) (161)
Fluoroprolines as Tools for Protein Design and Engineering. (2001) (161)
Towards the ecology of hyperthermophiles: biotopes, new isolation strategies and novel metabolic properties. (2000) (160)
X-ray structures and mechanistic implications of three functional derivatives of ascorbate oxidase from zucchini. Reduced, peroxide and azide forms. (1994) (160)
Early evolution of cytochrome bc complexes. (2000) (159)
Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. (2003) (157)
Crystal structure of human annexin I at 2.5 Å resolution (1993) (156)
Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors. (1995) (155)
Crystallization, crystal structure analysis and atomic model of the complex formed by a human Fc fragment and fragment B of protein A from Staphylococcus aureus. (1978) (154)
Three-dimensional structure of membrane-bound annexin V. A correlative electron microscopy-X-ray crystallography study. (1994) (152)
A novel strategy for inhibition of α-amylases: yellow meal worm α-amylase in complex with the Ragi bifunctional inhibitor at 2.5 å resolution (1998) (149)
Structural Basis of Fosmidomycin Action Revealed by the Complex with 2-C-Methyl-d-erythritol 4-phosphate Synthase (IspC) (2003) (149)
Crystal structure of plakalbumin, a proteolytically nicked form of ovalbumin. Its relationship to the structure of cleaved alpha-1-proteinase inhibitor. (1990) (148)
Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential. (1997) (147)
Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins. (1991) (147)
Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and X-ray refinement of crystal form II. (1984) (145)
Mutational studies on HslU and its docking mode with HslV. (2000) (145)
The 2.0-Å crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems (2001) (144)
Crystal structure of the pyridoxal-5'-phosphate dependent cystathionine beta-lyase from Escherichia coli at 1.83 A. (1996) (144)
Refined three-dimensional structure of phycoerythrocyanin from the cyanobacterium Mastigocladus laminosus at 2.7 A. (1990) (143)
Structure analysis and molecular model of the selenoenzyme glutathione peroxidase at 2.8 A resolution. (1979) (143)
Probing structural determinants specifying high thermostability in Bacillus licheniformis alpha-amylase. (2000) (142)
Gene sequence and the 1.8 A crystal structure of the tungsten-containing formate dehydrogenase from Desulfovibrio gigas. (2002) (140)
Crystallization, crystal structure analysis and preliminary molecular model of the bilin binding protein from the insect Pieris brassicae. (1987) (140)
Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly. (2000) (139)
Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins (2006) (139)
Comparison of the high-resolution structures of the alpha-amylase inhibitor tendamistat determined by nuclear magnetic resonance in solution and by X-ray diffraction in single crystals. (1989) (138)
X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design. (1995) (138)
The 1.8 A crystal structure of human cathepsin G in complex with Suc‐Val‐Pro‐PheP‐(OPh)2: a Janus‐faced proteinase with two opposite specificities. (1996) (137)
The ternary microplasmin–staphylokinase–microplasmin complex is a proteinase–cofactor–substrate complex in action (1998) (136)
Isolation, crystallization, crystal structure analysis and refinement of B-phycoerythrin from the red alga Porphyridium sordidum at 2.2 A resolution. (1992) (136)
Structural analysis at 2.2 A of orthorhombic crystals presents the asymmetry of the allophycocyanin-linker complex, AP.LC7.8, from phycobilisomes of Mastigocladus laminosus. (1999) (134)
Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug. (1997) (133)
Robo-Lector – a novel platform for automated high-throughput cultivations in microtiter plates with high information content (2009) (133)
Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein (2003) (132)
Hyperthermostabilization of Bacillus licheniformis α-amylase and modulation of its stability over a 50°C temperature range (2003) (132)
Refined 2.0 A X-ray crystal structure of the snake venom zinc-endopeptidase adamalysin II. Primary and tertiary structure determination, refinement, molecular structure and comparison with astacin, collagenase and thermolysin. (1994) (132)
Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins (2008) (130)
Three‐dimensional structure of porcine procarboxypeptidase B: a structural basis of its inactivity. (1991) (130)
Crystallographic refinement of Japanese quail ovomucoid, a Kazal-type inhibitor, and model building studies of complexes with serine proteases. (1982) (130)
Structure of the human antibody molecule Kol (immunoglobulin G1): an electron density map at 5 A resolution. (1976) (130)
The atomic structure of erythrocruorin in the light of the chemical sequence and its comparison with myoglobin. (1971) (129)
Heavy riboflavin synthase from Bacillus subtilis. Crystal structure analysis of the icosahedral beta 60 capsid at 3.3 A resolution. (1988) (129)
Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG. (2004) (129)
The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator. (1996) (128)
Kinetic Stabilization of Bacillus licheniformis α-Amylase through Introduction of Hydrophobic Residues at the Surface* (2003) (128)
Induction of the bovine trypsinogen—trypsin transition by peptides sequentially similar to the N‐terminus of trypsin (1976) (128)
Reaction mechanism of Escherichia coli dihydrodipicolinate synthase investigated by X-ray crystallography and NMR spectroscopy. (1997) (126)
The crystal structure of dihydrodipicolinate synthase from Escherichia coli at 2.5 A resolution. (1995) (126)
Refined 1.8 A X-ray crystal structure of astacin, a zinc-endopeptidase from the crayfish Astacus astacus L. Structure determination, refinement, molecular structure and comparison with thermolysin. (1994) (124)
New isolates and physiological properties of the Aquificales and description of Thermocrinis albus sp. nov. (2002) (124)
Thermosipho africanus gen. nov., Represents a New Genus of Thermophilic Eubacteria within the “Thermotogales” (1989) (123)
Hyperthermophilic archaebacteria within the crater and open-sea plume of erupting Macdonald Seamount (1990) (123)
Carbonate Dissolution in the Deep-Sea: Methods, Quantification and Paleoceanographic Application (1999) (122)
Crystal structure of three consecutive laminin-type epidermal growth factor-like (LE) modules of laminin gamma1 chain harboring the nidogen binding site. (1996) (122)
The crystal structure of porcine pancreatic alpha-amylase in complex with the microbial inhibitor Tendamistat. (1995) (121)
The structure of residues 7-16 of the A alpha-chain of human fibrinogen bound to bovine thrombin at 2.3-A resolution. (1994) (121)
Proteasome beta-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function. (1999) (121)
Crystal structure analysis and molecular model of human C3a anaphylatoxin. (1980) (121)
The 1.9-Å crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link (2002) (120)
Conformational constraints for protein self-cleavage in the proteasome. (1998) (120)
Zinc plays a key role in human and bacterial GTP cyclohydrolase I. (2000) (119)
The crystal structure and ion channel activity of human annexin II, a peripheral membrane protein. (1996) (119)
Crystal structure of yellow meal worm alpha-amylase at 1.64 A resolution. (1998) (118)
Characterization and crystal structure of zinc azurin, a by-product of heterologous expression in Escherichia coli of Pseudomonas aeruginosa copper azurin. (1992) (117)
Active site topology and reaction mechanism of GTP cyclohydrolase I. (1995) (116)
Structural implications for the role of the N terminus in the ‘superactivation’ of collagenases (1994) (116)
Thermotoga neapolitana sp. nov. of the extremely thermophilic, eubacterial genus Thermotoga (1988) (115)
Formation of ammonium from nitrate during chemolithoautotrophic growth of the extremely thermophilic bacterium ammonifex degensii gen. nov. sp. nov. (1996) (115)
X-ray crystal structure of the two site-specific mutants His35Gln and His35Leu of azurin from Pseudomonas aeruginosa. (1991) (115)
Crystal structures of transcription factor NusG in light of its nucleic acid‐ and protein‐binding activities (2002) (114)
Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding. (1999) (114)
Closed structure of phosphoglycerate kinase from Thermotoga maritima reveals the catalytic mechanism and determinants of thermal stability. (1997) (114)
Crystal structures of MMP-9 complexes with five inhibitors: contribution of the flexible Arg424 side-chain to selectivity. (2007) (113)
Lactate dehydrogenase from the hyperthermophilic bacterium thermotoga maritima: the crystal structure at 2.1 A resolution reveals strategies for intrinsic protein stabilization. (1998) (113)
Enzymes of the reductive citric acid cycle in the autotrophic eubacterium Aquifex pyrophilus and in the archaebacterium Thermoproteus neutrophilus (1993) (113)
Application of NMR in structural proteomics: screening for proteins amenable to structural analysis. (2002) (113)
Carbohydrate and protein-based inhibitors of porcine pancreatic alpha-amylase: structure analysis and comparison of their binding characteristics. (1996) (113)
HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues (2010) (112)
Catalytic Domain Structures of MT-SP1/Matriptase, a Matrix-degrading Transmembrane Serine Proteinase* (2002) (112)
Crystal structure and mechanism of human L‐arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis (1998) (112)
Atomic structure of GTP cyclohydrolase I. (1995) (112)
Structural basis of the adaptive molecular recognition by MMP9. (2002) (112)
The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder. (2011) (111)
The unique structure of archaeal ‘hami’, highly complex cell appendages with nano‐grappling hooks (2005) (111)
Activation of snake venom metalloproteinases by a cysteine switch‐like mechanism (1993) (111)
Crystal structure of Pseudomonas aeruginosa apo‐azurin at 1.85 Å resolution (1992) (111)
Annexin V: the key to understanding ion selectivity and voltage regulation? (1994) (111)
Protein quality control in the bacterial periplasm. (2011) (109)
Crystallographic structural studies of a human Fc fragment. II. A complete model based on a Fourier map at 3.5 A resolution. (1976) (109)
X-ray analysis and spectroscopic characterization of M121Q azurin. A copper site model for stellacyanin. (1993) (109)
Structure–kinetic relationship study of CDK8/CycC specific compounds (2013) (108)
Crystal structure of 12-oxophytodienoate reductase 3 from tomato: Self-inhibition by dimerization (2006) (108)
The 1.8-Å Crystal Structure of a Matrix Metalloproteinase 8-Barbiturate Inhibitor Complex Reveals a Previously Unobserved Mechanism for Collagenase Substrate Recognition* (2001) (108)
Three-dimensional structure of annexins (1997) (106)
Small structural changes account for the high thermostability of 1[4Fe-4S] ferredoxin from the hyperthermophilic bacterium Thermotoga maritima. (1996) (104)
Structures of deoxy- and carbonmonoxy-erythrocruorin. (1970) (103)
Flavin Mononucleotide-Based Fluorescent Reporter Proteins Outperform Green Fluorescent Protein-Like Proteins as Quantitative In Vivo Real-Time Reporters (2010) (103)
Halorhabdus tiamatea sp. nov., a non-pigmented, extremely halophilic archaeon from a deep-sea, hypersaline anoxic basin of the Red Sea, and emended description of the genus Halorhabdus. (2008) (101)
Crystal structure of herbicide-detoxifying maize glutathione S-transferase-I in complex with lactoylglutathione: evidence for an induced-fit mechanism. (1997) (101)
Lysine 156 promotes the anomalous proenzyme activity of tPA: X‐ray crystal structure of single‐chain human tPA (1997) (101)
The crystal and molecular structure of the third domain of silver pheasant ovomucoid (OMSVP3). (1985) (101)
Studies on the lumazine synthase/riboflavin synthase complex of Bacillus subtilis: crystal structure analysis of reconstituted, icosahedral beta-subunit capsids with bound substrate analogue inhibitor at 2.4 A resolution. (1995) (101)
X-ray structure of 12-oxophytodienoate reductase 1 provides structural insight into substrate binding and specificity within the family of OYE. (2001) (101)
The crystal structure of the novel snake venom plasminogen activator TSV-PA: a prototype structure for snake venom serine proteinases. (1998) (101)
Prokaryotic phylogenetic diversity and corresponding geochemical data of the brine-seawater interface of the Shaban Deep, Red Sea. (2002) (100)
Crystal structure of Citrobacter freundii restriction endonuclease Cfr10I at 2.15 A resolution. (1996) (100)
Interactions of phage P22 tails with their cellular receptor, Salmonella O-antigen polysaccharide. (1996) (100)
A model for the association of bovine pancreatic trypsin inhibitor with chymotrypsin and trypsin. (1972) (100)
Structure-based optimization of novel azepane derivatives as PKB inhibitors. (2004) (98)
2,6,10,15,19-Pentamethylicosenes in Methanolobus bombayensis, a marine methanogenic archaeon, and in Methanosarcina mazei (1997) (98)
Crystal structure of a DNA-dependent RNA polymerase (DNA primase) (2001) (97)
Design of anti- and pro-aggregation variants to assess the effects of methionine oxidation in human prion protein (2009) (97)
Structure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nuclease. (2005) (95)
An extended RNA binding surface through arrayed S1 and KH domains in transcription factor NusA. (2001) (95)
Cytochrome c Nitrite Reductase from Desulfovibrio desulfuricans ATCC 27774 (2003) (94)
Three-dimensional structure of porcine pancreatic procarboxypeptidase A. A comparison of the A and B zymogens and their determinants for inhibition and activation. (1992) (94)
Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure. (2001) (94)
Crystal structure of the peptidyl‐cysteine decarboxylase EpiD complexed with a pentapeptide substrate (2000) (93)
Crystal structure of bovine trypsinogen at 1-8 A resolution. I. Data collection, application of patterson search techniques and preliminary structural interpretation. (1976) (93)
Structure of soluble and membrane-bound human annexin V. (1991) (92)
Bivalency as a principle for proteasome inhibition. (1999) (91)
The Cfr10I restriction enzyme is functional as a tetramer. (1999) (91)
The structural basis of photosynthetic light reactions in bacteria (1985) (91)
The structure of recombinant human annexin VI in crystals and membrane-bound. (1996) (91)
Hyperthermostable mutants of Bacillus licheniformis alpha-amylase: thermodynamic studies and structural interpretation. (1997) (91)
Crystal structure of the hydrogenase maturating endopeptidase HYBD from Escherichia coli. (1999) (90)
Escherichia coli dihydrodipicolinate synthase. Identification of the active site and crystallization. (1992) (90)
The crystal structure of dihydrofolate reductase from Thermotoga maritima: molecular features of thermostability. (2000) (90)
Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase. (1998) (90)
The Crystal Structures of Zea mays and Arabidopsis 4-Hydroxyphenylpyruvate Dioxygenase (2004) (89)
Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition (2009) (88)
Conformational flexibility and its functional significance in some protein molecules (1979) (87)
Crystal structure of the tricorn protease reveals a protein disassembly line (2001) (87)
Specific inhibition of insect α-amylases: yellow meal worm α-amylase in complex with the Amaranth α-amylase inhibitor at 2.0 Å resolution (1999) (87)
Investigations on the maturation and regulation of archaebacterial proteasomes. (2003) (87)
Structure-function analysis of the ion channel selectivity filter in human annexin V. (1993) (86)
The thrombin E192Q–BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin (1997) (85)
Refined crystal structure of phycoerythrin from Porphyridium cruentum at 0.23-nm resolution and localization of the gamma subunit. (1993) (85)
Crystal structure analysis and molecular model of a complex of citrate synthase with oxaloacetate and S-acetonyl-coenzyme A. (1984) (85)
Determination of the three-dimensional structure of the bifunctional alpha-amylase/trypsin inhibitor from ragi seeds by NMR spectroscopy. (1995) (85)
Thermotoga thermarum sp. nov. and Thermotoga neapolitana occurring in African continental solfataric springs (1989) (85)
Structure of dihydrodipicolinate synthase of Nicotiana sylvestris reveals novel quaternary structure. (1997) (84)
Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design. (1996) (84)
Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations. (2005) (84)
Pyrobaculum gen. nov., a new genus of neutrophilic, rod-shaped archaebacteria from continental solfataras growing optimally at 100°C (1987) (84)
Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site. (2006) (84)
Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin (1995) (84)
The crystal structure of human alpha1-tryptase reveals a blocked substrate-binding region. (2002) (83)
Human beta-tryptase is a ring-like tetramer with active sites facing a central pore. (1998) (82)
Divining the serpin inhibition mechanism: a suicide substrate 'springe'? (1995) (82)
Structural basis for the regulation of insulin-like growth factors by IGF binding proteins. (2006) (82)
Structure quality and target parameters (2006) (81)
Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor. (1996) (81)
Thermodynamic stability of annexin V E17G: equilibrium parameters from an irreversible unfolding reaction. (1997) (81)
The 0.25-nm X-ray structure of the Bowman-Birk-type inhibitor from mung bean in ternary complex with porcine trypsin. (1993) (81)
Probing structural determinants distal to the site of hydrolysis that control substrate specificity of the 20S proteasome. (2002) (81)
Structural basis of the zinc inhibition of human tissue kallikrein 5. (2007) (81)
Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 A resolution. (1998) (80)
Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration. (1999) (80)
Refined crystal structure of porcine class Pi glutathione S-transferase (pGST P1-1) at 2.1 A resolution. (1994) (80)
Isolation, characterization and electron microscopic single particle analysis of the NADH:ubiquinone oxidoreductase (complex I) from the hyperthermophilic eubacterium Aquifex aeolicus. (2003) (79)
Site‐directed mutagenesis and structural interpretation of the nidogen binding site of the laminin gamma1 chain. (1996) (79)
Atomic mutations at the single tryptophan residue of human recombinant annexin V: effects on structure, stability, and activity. (1999) (78)
Advances in metallo-procarboxypeptidases. Emerging details on the inhibition mechanism and on the activation process. (1993) (78)
Crystal structure of Escherichia coli cystathionine γ‐synthase at 1.5 Å resolution (1998) (78)
Ligand binding: proteinase-protein inhibitor interactions (1991) (78)
Crystal Structure of Klebsiella aerogenesUreE, a Nickel-binding Metallochaperone for Urease Activation* (2001) (78)
Crystal structure of desulforedoxin from Desulfovibrio gigas determined at 1.8 A resolution: a novel non-heme iron protein structure. (1995) (77)
Hydrothermal vents in Lake Tanganyika, East African, Rift system (1993) (77)
The refined 2.2-A (0.22-nm) X-ray crystal structure of the ternary complex formed by bovine trypsinogen, valine-valine and the Arg15 analogue of bovine pancreatic trypsin inhibitor. (1984) (76)
Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2 (2000) (76)
Conformational variability of chicken cystatin. Comparison of structures determined by X-ray diffraction and NMR spectroscopy. (1993) (76)
Structures of herbicides in complex with their detoxifying enzyme glutathione S-transferase - explanations for the selectivity of the enzyme in plants. (1998) (76)
Chymotryptic specificity determinants in the 1.0 Å structure of the zinc-inhibited human tissue kallikrein 7 (2007) (75)
Cloning, sequencing, crystallization and X-ray structure of glutathione S-transferase-III from Zea mays var. mutin: a leading enzyme in detoxification of maize herbicides. (1997) (75)
The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa. (1997) (75)
Natural Communities of Novel Archaea and Bacteria with a String-of-Pearls-Like Morphology: Molecular Analysis of the Bacterial Partners (2002) (75)
Structural basis for Ca2+-independence and activation by homodimerization of tomato subtilase 3 (2009) (74)
The proteasome. (1999) (73)
Crystal structure of the human CCA-adding enzyme: insights into template-independent polymerization. (2003) (73)
The persisting challenge of selective and specific proteasome inhibition (2009) (73)
Glutaconate CoA-transferase from Acidaminococcus fermentans: the crystal structure reveals homology with other CoA-transferases. (1997) (73)
Thermus thermophilus cytochrome-c552: A new highly thermostable cytochrome-c structure obtained by MAD phasing. (1997) (72)
Human High Temperature Requirement Serine Protease A1 (HTRA1) Degrades Tau Protein Aggregates* (2012) (72)
Pancreatic Trypsin Inhibitor (Kunitz) Part I: Structure and function (1972) (71)
Annexin 24 from Capsicum annuum (2000) (71)
Residue-specific bioincorporation of non-natural, biologically active amino acids into proteins as possible drug carriers: structure and stability of the per-thiaproline mutant of annexin V. (1998) (71)
Crystal structures of active SRC kinase domain complexes. (2005) (70)
Global replacement of tryptophan with aminotryptophans generates non-invasive protein-based optical pH sensors. (2002) (70)
A dissimilatory sirohaem-sulfite-reductase-type protein from the hyperthermophilic archaeon Pyrobaculum islandicum. (1998) (70)
The Three-dimensional Structure of Recombinant Leech-derived Tryptase Inhibitor in Complex with Trypsin (1997) (69)
Crystal structure of MunI restriction endonuclease in complex with cognate DNA at 1.7 Å resolution (1999) (69)
High Thermostability and Lack of Cooperative DNA Binding Distinguish the p63 Core Domain from the Homologous Tumor Suppressor p53* (2001) (69)
Evidence for the extent of insertion of the active site loop of intact alpha 1 proteinase inhibitor in beta-sheet A. (1992) (68)
A New Lineage of Halophilic, Wall-Less, Contractile Bacteria from a Brine-Filled Deep of the Red Sea (2008) (68)
Crystal structure of the human α‐thrombin–haemadin complex: an exosite II‐binding inhibitor (2000) (68)
Crystallization, crystal structure analysis and molecular model of the third domain of Japanese quail ovomucoid, a Kazal type inhibitor. (1981) (68)
Reverse gyrase in thermophilic eubacteria (1991) (67)
The core structure of TMC-95A is a promising lead for reversible proteasome inhibition. (2002) (67)
Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism (2016) (67)
Nickel serves as a substrate recognition motif for the endopeptidase involved in hydrogenase maturation. (2000) (67)
Sulfur-inhibited Thermosphaera aggregans sp. nov., a new genus of hyperthermophilic archaea isolated after its prediction from environmentally derived 16S rRNA sequences. (1998) (66)
Phylum All. Euryarchaeota phy. nov. (2001) (66)
Salinisphaerashabanensis gen. nov., sp. nov., a novel, moderately halophilic bacterium from the brine–seawater interface of the Shaban Deep, Red Sea (2003) (66)
Structural Mapping of the Active Site Specificity Determinants of Human Tissue-type Plasminogen Activator (1997) (66)
Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I. (2003) (66)
Structures of class pi glutathione S-transferase from human placenta in complex with substrate, transition-state analogue and inhibitor. (1997) (65)
The substrate translocation channel of the proteasome. (2001) (65)
Ecology and microbial structures of archaeal/bacterial strings-of-pearls communities and archaeal relatives thriving in cold sulfidic springs. (2004) (64)
Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions. (2002) (64)
The Role of Se, Mo and Fe in the Structure and Function of Carbon Monoxide Dehydrogenase (2000) (64)
Active site geometry and substrate recognition of the molybdenum hydroxylase quinoline 2-oxidoreductase. (2004) (64)
Thermococcus chitonophagus sp. nov., a novel, chitin-degrading, hyperthermophilic archaeum from a deep-sea hydrothermal vent environment (1995) (63)
Bifunctional inhibitors of the trypsin-like activity of eukaryotic proteasomes. (1999) (63)
Fervidobacterium islandicum sp. nov., a new extremely thermophilic eubacterium belonging to the “Thermotogales” (1990) (63)
Inhibition of carboxypeptidase A by excess zinc: analysis of the structural determinants by X‐ray crystallography (1997) (63)
Crystal structure of the cystine C-S lyase from Synechocystis: stabilization of cysteine persulfide for FeS cluster biosynthesis. (2000) (63)
Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY) (2002) (63)
Crystal structure of the dinuclear zinc aminopeptidase PepV from Lactobacillus delbrueckii unravels its preference for dipeptides. (2002) (63)
Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution. (1992) (63)
Slow-binding inhibition of Escherichia coli cystathionine beta-lyase by L-aminoethoxyvinylglycine: a kinetic and X-ray study. (1997) (63)
Crystal Structure of the Caspase Activator Human Granzyme B, a Proteinase Highly Specific for an Asp-P1 Residue (2000) (63)
The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase. (2002) (63)
Inhibitor-binding mode of homobelactosin C to proteasomes: new insights into class I MHC ligand generation. (2006) (62)
Bioincorporation of telluromethionine into proteins: a promising new approach for X-ray structure analysis of proteins. (1997) (62)
Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence. (2002) (62)
The effect of intracellular molybdenum in Hydrogenophaga pseudoflava on the crystallographic structure of the seleno-molybdo-iron-sulfur flavoenzyme carbon monoxide dehydrogenase. (2000) (62)
Structure and function of molybdopterin containing enzymes. (1997) (62)
Ta6Br122+, a tool for phase determination of large biological assemblies by X-ray crystallography (1997) (62)
Hydroxyureas as noncovalent proteasome inhibitors. (2012) (61)
Syringolin A Selectively Labels the 20 S Proteasome in Murine EL4 and Wild‐Type and Bortezomib‐Adapted Leukaemic Cell Lines (2009) (61)
Crystal structure determination, refinement and molecular model of creatine amidinohydrolase from Pseudomonas putida. (1988) (61)
The Order Thermotogales (1992) (61)
The lumazine synthase/riboflavin synthase complex of Bacillus subtilis. X-ray structure analysis of hollow reconstituted beta-subunit capsids. (1994) (61)
X‐ray structures of Sap1 and Sap5: Structural comparison of the secreted aspartic proteinases from Candida albicans (2008) (60)
(4-aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase. (2000) (60)
In situ growth of the novel SM1 euryarchaeon from a string-of-pearls-like microbial community in its cold biotope, its physical separation and insights into its structure and physiology (2003) (60)
Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. (2004) (60)
Studies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8-ribityllumazine. (2002) (59)
Carbonate preservation records of the past 3 Myr in the Norwegian–Greenland Sea and the northern North Atlantic: implications for the history of NADW production (2002) (59)
The S variant of human α1-antitrypsin, structure and implications for function and metabolism (1990) (59)
A porin‐type protein is the main constituent of the cell envelope of the ancestral eubacterium Thermotoga maritima (1990) (58)
Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli. (2009) (58)
A rapid and efficient purification method for recombinant annexin V for biophysical studies (1993) (58)
Utilizing high-throughput experimentation to enhance specific productivity of an E.coli T7 expression system by phosphate limitation (2011) (57)
The isolation and characterization of cytochrome c nitrite reductase subunits (NrfA and NrfH) from Desulfovibrio desulfuricans ATCC 27774. Re-evaluation of the spectroscopic data and redox properties. (2003) (57)
Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex (2001) (57)
The three-dimensional structures of tick carboxypeptidase inhibitor in complex with A/B carboxypeptidases reveal a novel double-headed binding mode. (2005) (56)
Functional properties of native and reconstituted hemoglobins from Chironomus thummi thummi. (1972) (56)
Cytochrome-c552 from Thermus thermophilus: a functional and crystallographic investigation. (1997) (56)
The three‐dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C. (1995) (56)
Class π glutathione S-transferase from pig lung (1991) (56)
Life in hot springs and hydrothermal vents (1993) (55)
1.2 A crystal structure of the serine carboxyl proteinase pro-kumamolisin; structure of an intact pro-subtilase. (2004) (55)
Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin. (2004) (54)
Modeling the intact form of the α1-proteinase inhibitor (1990) (54)
Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV. (2006) (54)
Molecular structure of the rod domain of dictyostelium filamin. (2004) (54)
Pancreatic trypsin inhibitor. A new crystal form and its analysis. (1983) (54)
The effect of metal binding on the structure of annexin V and implications for membrane binding. (1992) (54)
A robust metallo‐oxidase from the hyperthermophilic bacterium Aquifex aeolicus (2007) (54)
[NiFe]-Hydrogenase maturation endopeptidase: structure and function. (2005) (53)
Structure refinement of the aldehyde oxidoreductase from Desulfovibriogigas (MOP) at 1.28 Å (2001) (53)
Purification, crystallization, and X-ray analysis of the yeast 20S proteasome. (2005) (53)
Crystal structure of Schizosaccharomyces pombe riboflavin kinase reveals a novel ATP and riboflavin-binding fold. (2003) (53)
Peptidyl prolyl cis/trans-isomerases: comparative reactivities of cyclophilins, FK506-binding proteins, and parvulins with fluorinated oligopeptide and protein substrates. (2005) (53)
Marinobacter salsuginis sp. nov., isolated from the brine-seawater interface of the Shaban Deep, Red Sea. (2007) (53)
Structure of human cyclin-dependent kinase inhibitor p19INK4d: comparison to known ankyrin-repeat-containing structures and implications for the dysfunction of tumor suppressor p16INK4a. (1998) (53)
Gene sequence and crystal structure of the aldehyde oxidoreductase from Desulfovibrio desulfuricans ATCC 27774. (2000) (52)
New Insights into the Lifestyle of the Cold-Loving SM1 Euryarchaeon: Natural Growth as a Monospecies Biofilm in the Subsurface (2006) (52)
Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants. (2005) (52)
Crystal structure of the human Fab fragment Kol and its comparison with the intact Kol molecule. (1978) (52)
Structure of chicken annexin V at 2.25-A resolution. (1993) (50)
Towards New Protein Engineering: In Vivo Building and Folding of Protein Shuttles for Drug Delivery and Targeting by the Selective Pressure Incorporation (SPI) Method (2000) (50)
Crystal structure of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Bacillus subtilis. (2003) (50)
Lactate dehydrogenase from the extreme thermophile Thermotoga maritima. (1990) (50)
Open and Closed Structures of the UDP-glucose Pyrophosphorylase from Leishmania major* (2007) (50)
Convergent Synthesis and Biological Evaluation of Syringolin A and Derivatives as Eukaryotic 20S Proteasome Inhibitors (2010) (50)
Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite (2009) (50)
Structural and functional characterisation of the voltage sensor in the ion channel human annexin V. (1996) (49)
Crystal structure of the plant PPC decarboxylase AtHAL3a complexed with an ene-thiol reaction intermediate. (2003) (49)
Mutants of protein kinase A that mimic the ATP-binding site of protein kinase B (AKT). (2003) (49)
The three-dimensional structure of cystathionine beta-lyase from Arabidopsis and its substrate specificity. (2001) (49)
Crystallographic structural studies of a human Fc-fragment. I. An electron-density map at 4 A resolution and a partial model. (1976) (49)
Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter. (1995) (49)
Molecular cloning and sequence analysis of the gene of the molybdenum-containing aldehyde oxido-reductase of Desulfovibrio gigas. The deduced amino acid sequence shows similarity to xanthine dehydrogenase. (1994) (48)
Enzymatic mechanism of creatine amidinohydrolase as deduced from crystal structures. (1990) (48)
The multicopper oxidase from the archaeon Pyrobaculum aerophilum shows nitrous oxide reductase activity (2010) (48)
Sulfide:quinone oxidoreductase in membranes of the hyperthermophilic bacterium Aquifexaeolicus (VF5) (2000) (48)
The crystal structure of murine CMP-5-N-acetylneuraminic acid synthetase. (2003) (48)
Determinants of structural and functional plasticity of a widely conserved protease chaperone complex (2010) (48)
Structural basis of substrate specificity of plant 12-oxophytodienoate reductases. (2009) (47)
Structure-based redesign of the catalytic/metal binding site of Cfr10I restriction endonuclease reveals importance of spatial rather than sequence conservation of active centre residues. (1998) (47)
Recent and Pleistocene carbonate dissolution in sediments of the Norwegian–Greenland Sea (2000) (47)
Inhibitory activity and conformational transition of alpha 1-proteinase inhibitor variants. (1991) (46)
The structure of oxy-erythrocruorin at 1.4 X resolution. (1978) (46)
Nobel lecture. A structural basis of light energy and electron transfer in biology. (1989) (46)
Crystal structure analysis and refinement at 2.15 A resolution of amicyanin, a type I blue copper protein, from Thiobacillus versutus. (1994) (46)
The 2.0 A crystal structure and substrate specificity of the KDEL-tailed cysteine endopeptidase functioning in programmed cell death of Ricinus communis endosperm. (2004) (46)
Structures of the tricorn‐interacting aminopeptidase F1 with different ligands explain its catalytic mechanism (2002) (46)
Brain morphology and turbidity preference in Notropis and related genera (Cyprinidae, Teleostei) (2004) (46)
Crystal structure of transcription factor MalT domain III: a novel helix repeat fold implicated in regulated oligomerization. (2001) (46)
Crystal structure of the catalytic domain of human tumor necrosis factor-a-converting enzyme (1998) (45)
Structure of MrsD, an FAD-binding protein of the HFCD family. (2003) (45)
Atomic mutations in annexin V--thermodynamic studies of isomorphous protein variants. (1998) (45)
Conformational flexibility in protein molecules (1979) (45)
Mutational substitution of residues implicated by crystal structure in binding the substrate glutathione to human glutathione S-transferase pi. (1992) (45)
Isolation of the globular region of the subcomponent q of the C1 component of complement. (1979) (45)
The domains of protein S from Myxococcus xanthus: structure, stability and interactions. (1999) (45)
Extremely thermophilic sulfur-metabolizing archaebacteria (1986) (45)
Binding of Flavin Adenine Dinucleotide to Molybdenum-containing Carbon Monoxide Dehydrogenase from Oligotropha carboxidovorans (2000) (45)
Nuclear magnetic resonance solution and X-ray structures of squash trypsin inhibitor exhibit the same conformation of the proteinase binding loop. (1989) (45)
Binding Mode of TMC‐95A Analogues to Eukaryotic 20S Proteasome (2004) (44)
Gene Transfer and Genome Plasticity in Thermotoga maritima, a Model Hyperthermophilic Species (2005) (44)
Catalytic domain structure of vampire bat plasminogen activator: a molecular paradigm for proteolysis without activation cleavage. (1997) (44)
Crystal structure of holo inorganic pyrophosphatase from Escherichia coli at 1.9 A resolution. Mechanism of hydrolysis. (1997) (44)
20S Proteasome Inhibition: Designing Noncovalent Linear Peptide Mimics of the Natural Product TMC‐95A (2010) (44)
Discovery of hyperthermophilic microorganisms. (2001) (44)
Complete sequential 1H and 15N nuclear magnetic resonance assignments and solution secondary structure of the blue copper protein azurin from Pseudomonas aeruginosa. (1992) (44)
Histidine 179 Mutants of GTP Cyclohydrolase I Catalyze the Formation of 2-Amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone Triphosphate* (1999) (44)
Structure and Properties of an Engineered Transketolase from Maize1 (2003) (43)
Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer (2018) (43)
New enzyme lineages by subdomain shuffling. (1998) (43)
Enzyme catalysis via control of activation entropy: site-directed mutagenesis of 6,7-dimethyl-8-ribityllumazine synthase. (2003) (43)
Electrostatic evidence for the activation of the glutathione thiol by Tyr7 in pi-class glutathione transferases. (1993) (43)
The 1.4 a crystal structure of kumamolysin: a thermostable serine-carboxyl-type proteinase. (2002) (43)
The cell envelope of the hyperthermophilic archaebacterium Pyrobaculum organotrophum consists of two regularly arrayed protein layers: three‐dimensional structure of the outer layer (1991) (42)
Shell size variation of the planktonic foraminifer Neogloboquadrina pachyderma sin. in the Norwegian–Greenland Sea during the last 1.3 Myrs: implications for paleoceanographic reconstructions (2000) (42)
Conformational analysis of a IgG1 hinge peptide derivative in solution determined by NMR spectroscopy and refined by restrained molecular dynamics simulations (1991) (42)
Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera. (2001) (42)
The Protein Kinase C Inhibitor Bisindolyl Maleimide 2 Binds with Reversed Orientations to Different Conformations of Protein Kinase A* (2004) (42)
Serotonin depletion by 5,7-dihydroxytryptamine alters deutocerebral development in the lobster, Homarus americanus. (1997) (42)
Crystallographic evidence for the tetrameric subunit structure of L-asparaginase from Escherichia coli. (1971) (42)
Evolution of vitamin B2 biosynthesis. A novel class of riboflavin synthase in Archaea. (2004) (41)
The annexin A3-membrane interaction is modulated by an N-terminal tryptophan. (2000) (41)
Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain. (2007) (41)
Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation (2010) (41)
Crystal Structure and Substrate Binding Modeling of the Uroporphyrinogen-III Decarboxylase from Nicotiana tabacum (2001) (41)
Design, synthesis, and evaluation of 6-carboxyalkyl and 6-phosphonoxyalkyl derivatives of 7-oxo-8-ribitylaminolumazines as inhibitors of riboflavin synthase and lumazine synthase. (2002) (40)
Crystal structure determination and refinement of pike 4.10 parvalbumin (minor component from Esox lucius). (1988) (40)
Distribution of Complex and Core Lipids within New Hyperthermophilic Members of the Archaea Domain (1992) (40)
The α‐amylase from the yellow meal worm: complete primary structure, crystallization and preliminary X‐ray analysis (1997) (40)
Some observations of a correlation between the symmetry of large heavy-atom complexes and their binding sites on proteins. (1987) (39)
Physiological fIXa Activation Involves a Cooperative Conformational Rearrangement of the 99-Loop* (2003) (39)
Structural and spectral response of Aequorea victoria green fluorescent proteins to chromophore fluorination. (2005) (39)
Flt3 is a target of coumestrol in protecting against UVB-induced skin photoaging. (2015) (39)
A new 15,16-dimethyl-30-glyceryloxytriacontanoic acid from lipids of Thermotoga maritima (1988) (39)
Structural analysis of the human fibroblast growth factor receptor 4 kinase. (2014) (39)
Catalytic mechanism of the 20S proteasome of Thermoplasma acidophilum revealed by X-ray crystallography. (1995) (38)
X-ray crystallographic characterisation of type-2-depleted ascorbate oxidase from zucchini. (1992) (38)
Demyelinating Myelin Oligodendrocyte Glycoprotein-Specific Autoantibody Response Is Focused on One Dominant Conformational Epitope Region in Rodents12 (2008) (38)
Rack-induced metal binding vs. flexibility: Met121His azurin crystal structures at different pH. (1998) (38)
The basic trypsin inhibitor of bovine pancreas (1970) (38)
Heavy riboflavin synthase from Bacillus subtilis. Particle dimensions, crystal packing and molecular symmetry. (1986) (38)
Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family (2007) (37)
Crystal structure of L-arginine:inosamine-phosphate amidinotransferase StrB1 from Streptomyces griseus: an enzyme involved in streptomycin biosynthesis. (1998) (37)
Incorporation of β-selenolo[3,2-b]pyrrolyl-alanine into proteins for phase determination in protein X-ray crystallography (2001) (37)
Crystal structure of the carboxyltransferase subunit of the bacterial sodium ion pump glutaconyl‐coenzyme A decarboxylase (2003) (37)
The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin A (2007) (37)
Structure of malonic acid‐based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data (1998) (37)
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe. (2002) (37)
Crystal structure analysis, refinement and enzymatic reaction mechanism of N-carbamoylsarcosine amidohydrolase from Arthrobacter sp. at 2.0 A resolution. (1992) (36)
The endoproteinase furin contains two essential Ca2+ ions stabilizing its N-terminus and the unique S1 specificity pocket. (2005) (36)
A cryptic miniplasmid from the hyperthermophilic bacterium Thermotoga sp. strain RQ7 (1994) (36)
New insights into the thermostability of bacterial ferredoxins: high-resolution crystal structure of the seven-iron ferredoxin from Thermus thermophilus (2001) (36)
The crystal structure of the Physarum polycephalum actin–fragmin kinase: an atypical protein kinase with a specialized substrate‐binding domain (1999) (36)
Crystal Structure of Paprika Ferredoxin-NADP+Reductase (2001) (36)
Mutations that stabilize folding intermediates of phage P22 tailspike protein: folding in vivo and in vitro, stability, and structural context. (1995) (36)
A cold-loving crenarchaeon is a substantial part of a novel microbial community in cold sulphidic marsh water. (2006) (36)
Crystal structure analysis of the tetragonal crystal form are preliminary molecular model of pig-heart citrate synthase. (1979) (36)
Pulse-radiolysis studies on the oxidised form of the multicopper enzyme ascorbate oxidase: evidence for two intramolecular electron-transfer steps (1993) (35)
A variant of the hyperthermophile Archaeoglobus fulgidus adapted to grow at high salinity. (2003) (35)
Equalizing growth in high‐throughput small scale cultivations via precultures operated in fed‐batch mode (2009) (34)
X‐ray Structures of Human Neutrophil Collagenase Complexed with Peptide Hydroxamate and Peptide Thiol Inhibitors (1995) (34)
The typically disordered N-terminus of PKA can fold as a helix and project the myristoylation site into solution. (2004) (34)
Solution of the phase problem in the X-ray diffraction method for proteins with the nuclear magnetic resonance solution structure as initial model. Patterson search and refinement for the alpha-amylase inhibitor tendamistat. (1989) (34)
The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity. (1999) (34)
Structure of the nidogen binding LE module of the laminin gamma1 chain in solution. (1996) (34)
Proteinase-protein inhibitor interaction. (1991) (34)
[Elucidation of the molecular structure of insect hemoglobin]. (1969) (34)
Recombinant expression and isolation of human L-arginine:glycine amidinotransferase and identification of its active-site cysteine residue. (1997) (33)
The complex structures of ATP sulfurylase with thiosulfate, ADP and chlorate reveal new insights in inhibitory effects and the catalytic cycle. (2001) (33)
S100A1 and S100B interactions with annexins. (2000) (33)
Noninvasive tracing of recombinant proteins with "fluorophenylalanine-fingers". (2000) (33)
The crystal structure of cystathionine gamma-synthase from Nicotiana tabacum reveals its substrate and reaction specificity. (1999) (33)
X-ray structure of isoaspartyl dipeptidase from E.coli: a dinuclear zinc peptidase evolved from amidohydrolases. (2003) (33)
Snapshots of the Cystine Lyase C-DES during Catalysis (2003) (33)
Structure and Function of Threonine Synthase from Yeast* (2002) (33)
A precisely positioned MED12 activation helix stimulates CDK8 kinase activity (2020) (33)
Dynamics of the aromatic amino acid residues in the globular conformation of the basic pancreatic trypsin inhibitor (BPTI) (1976) (32)
Substrate Oxidation in the Active Site of Xanthine Oxidase and Related Enzymes. A Model Density Functional Study (1998) (32)
Crystal Structure of an Archaeal Pentameric Riboflavin Synthase in Complex with a Substrate Analog Inhibitor (2006) (32)
Phylum BI. Aquificae phy. nov. (2001) (32)
Three-Dimensional Structure of the Crystalline Protein Envelope Layer of the Hyperthermophilic Archaebacterium Pyrobaculum islandicum (1990) (32)
The 2.0A resolution structure of the catalytic portion of a cyanobacterial membrane-bound manganese superoxide dismutase. (2002) (32)
Structure and function of the xanthine-oxidase family of molybdenum enzymes (1998) (31)
Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements* (2005) (31)
Antibody–antigen flexibility (1987) (31)
Simultaneous refinement of the structure of BPTI against NMR data measured in solution and X-ray diffraction data measured in single crystals. (1994) (31)
Biosynthesis of riboflavin: structure and properties of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase of Methanocaldococcus jannaschii. (2006) (31)
Proteasome: from structure to function. (1996) (31)
Structural and functional analysis of the natural JNK1 inhibitor quercetagetin. (2013) (31)
Elucidation of the α-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition. (2011) (30)
The structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor (1975) (30)
Engineering the thermostability of Bacillus licheniformis alpha-amylase (2002) (30)
Flexibility and Rigidity of Proteins and Protein–Pigment Complexes (1988) (30)
Engineering the thermostability of Bacillus licheniformis -amylase (2002) (30)
Mechanism of interaction of cysteine proteinases and their protein inhibitors as compared to the serine proteinase-inhibitor interaction. (1990) (30)
The influence of residue 190 in the S1 site of trypsin‐like serine proteases on substrate selectivity is universally conserved (2002) (30)
Molecular architecture of the Spire–actin nucleus and its implication for actin filament assembly (2011) (29)
Detection of cell viability in cultures of hyperthermophiles (1997) (29)
Isolation and characterization of the prokaryotic proteasome homolog HslVU (ClpQY) from Thermotoga maritima and the crystal structure of HslV. (2002) (29)
Primary structure of a novel subunit in ba3‐cytochrome oxidase from thermus thermophilus (2000) (29)
Flexibility and rigidity, requirements for the function of proteins and protein pigment complexes. Eleventh Keilin memorial lecture. (1987) (28)
Predictive tool for recombinant protein production in Escherichia coli Shake‐Flask cultures using an on‐line monitoring system (2012) (28)
Voltage dependent binding of annexin V, annexin VI and annexin VII-core to acidic phospholipid membranes. (1997) (28)
Structural basis for the interaction of Escherichia coli NusA with protein N of phage lambda. (2004) (28)
Potential anti-infective targets in pathogenic yeasts: structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans. (2004) (27)
The environment of the haem group in erythrocruorin (Chironomus thummi). (1969) (27)
Interactions of Benzodiazepine Derivatives with Annexins* (1998) (27)
Glycolipids from Thermotoga maritima, a hyperthermophilic microorganism belonging to Bacteria domain. (1992) (27)
Structure of 3,4-Dihydroxy-2-butanone 4-Phosphate Synthase from Methanococcus jannaschii in Complex with Divalent Metal Ions and the Substrate Ribulose 5-Phosphate (2003) (27)
Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding (2014) (27)
Annexin V and vesicle membrane electroporation (1997) (27)
The role of hyperthermophilic prokaryotes in oil fields (1999) (26)
Reaction mechanism of GTP cyclohydrolase I: single turnover experiments using a kinetically competent reaction intermediate. (2002) (26)
The calcium-dependent binding of annexin V to phospholipid vesicles influences the bilayer inner fluidity gradient. (1998) (26)
Altered specificity mutations define residues essential for substrate positioning in xanthine dehydrogenase. (1998) (26)
Phylum BII. Thermotogae phy. nov. (2001) (26)
X-ray crystal structure of the two site-specific mutants Ile7Ser and Phe110Ser of azurin from Pseudomonas aeruginosa. (1996) (26)
Refined X-ray crystal structures of the reactive site modified ovomucoid inhibitor third domains from silver pheasant (OMSVP3*) and from Japanese quail (OMJPQ3*). (1991) (26)
Biosynthesis of Riboflavin in Archaea Studies on the Mechanism of 3,4-Dihydroxy-2-butanone-4-phosphate Synthase of Methanococcus jannaschii * (2002) (26)
Interaction of human alpha 1-proteinase inhibitor with chymotrypsinogen A and crystallization of a proteolytically modified alpha 1-proteinase inhibitor. (1982) (26)
Crystal structure of an oligomer of proteolytic zymogens: detailed conformational analysis of the bovine ternary complex and implications for their activation. (1997) (26)
Hyperthermophilic Archaea and Bacteria Occurring within Indonesian Hydrothermal Areas (1991) (25)
Navigation inside a protease: substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum. (2002) (25)
Structural basis for the function of pyridoxine 5'-phosphate synthase. (2001) (25)
Structural basis of charge transfer complex formation by riboflavin bound to 6,7-dimethyl-8-ribityllumazine synthase. (2004) (25)
X-ray Structures of Free and Leupeptin-complexed Human αI-Tryptase Mutants: Indication for an α→β-Tryptase Transition (2006) (24)
Phosphorylation and flexibility of cyclic-AMP-dependent protein kinase (PKA) using (31)P NMR spectroscopy. (2002) (24)
The crystal structure of the rare-cutting restriction enzyme SdaI reveals unexpected domain architecture. (2006) (24)
Transdisciplinary EU science institute needs funds urgently (2010) (24)
Cloning and sequencing of the gene coding for topoisomerase I from the extremely thermophilic eubacterium, Thermotoga maritima. (1995) (24)
Impact of protein-protein contacts on the conformation of thrombin-bound hirudin studied by comparison with the nuclear magnetic resonance solution structure of hirudin(1-51). (1992) (24)
Replication methods and tools in high-throughput cultivation processes - recognizing potential variations of growth and product formation by on-line monitoring (2010) (24)
Structural basis of CTP-dependent peptide bond formation in coenzyme A biosynthesis catalyzed by Escherichia coli PPC synthetase. (2004) (24)
The molybdenum and tungsten cofactors: a crystallographic view. (2002) (24)
Increased product formation induced by a directed secondary substrate limitation in a batch Hansenula polymorpha culture (2010) (24)
Low‐temperature protein crystallography. Effect on flexibility, temperature factor, mosaic spread, extinction and diffuse scattering in two examples: bovine trypsinogen and Fc fragment (1980) (23)
Crystal structure of the C-terminal tetrad repeat from synexin (annexin VII) of Dictyostelium discoideum. (1997) (23)
The structure of γ‐N‐methylasparagine in C‐phycocyanin from Mastigocladus laminosus and Agmenellum quadruplicatum (1988) (23)
Three-dimensional Reconstruction of the Surface Protein of the Extremely Thermophilic Archaebacterium Archaeoglobus fulgidus (1990) (23)
Crystallographic and fluorescence studies of ligand binding to N-carbamoylsarcosine amidohydrolase from Arthrobacter sp. (1996) (23)
A novel strategy for inhibition of alpha-amylases: yellow meal worm alpha-amylase in complex with the Ragi bifunctional inhibitor at 2.5 A resolution. (1998) (23)
Chemical modification of GSH transferase P1-1 confirms the presence of Arg-13, Lys-44 and one carboxylate group in the GSH-binding domain of the active site. (1993) (23)
Unusual reactivity of Tyr-7 of GSH transferase P1-1. (1993) (23)
Di-myo-inositol phosphate and novel UDP-sugars accumulate in the extreme hyperthermophile Pyrolobus fumarii (2008) (23)
Acid induced equilibrium unfolding of annexin V wild type shows two intermediate states (1998) (23)
Biosynthesis of riboflavin: structure and mechanism of lumazine synthase. (1996) (22)
Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor. (2001) (22)
Crystal structure of Escherichia coli cystathionine gamma-synthase at 1.5 A resolution. (1998) (22)
Preliminary X-ray crystallographic study of the proteasome from Thermoplasma acidophilum. (1993) (22)
Prediction of Alternative Structures of the Molybdenum Site in the Xanthine Oxidase-Related Aldehyde Oxido Reductase (1997) (22)
Structural and functional studies of the yeast class II Hda1 histone deacetylase complex. (2009) (22)
Quantitative histological study of the optic nerve in species of minnows (Cyprinidae, Teleostei) inhabiting clear and turbid water. (1992) (22)
Correlation of metal decoration and topochemistry on protein surfaces. (1991) (22)
Structure of the Complex Formed by Bovine Trypsin and Bovine Pancreatic Trypsin Inhibitor Refinement of the Crystal Structure Analysis (1974) (22)
The 1.1 A resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity. (2005) (22)
X-ray Snapshots of Peptide Processing in Mutants of Tricorn-interacting Factor F1 from Thermoplasma acidophilum* (2005) (22)
Structure and Function of the Tetrameric Restriction Enzymes (2004) (21)
Annexin V membrane interaction: an electrostatic potential study (2004) (21)
Ribosomes of the extremely thermophilic eubacterium Thermotoga maritima are uniquely insensitive to the miscoding-inducing action of aminoglycoside antibiotics (1988) (21)
Progress toward forecasting product quality and quantity of mammalian cell culture processes by performance‐based modeling (2015) (21)
Incorporation of an amide into 5-phosphonoalkyl-6-D-ribitylaminopyrimidinedione lumazine synthase inhibitors results in an unexpected reversal of selectivity for riboflavin synthase vs lumazine synthase. (2002) (21)
Characterization of the residues involved in the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor. (2002) (21)
Crystallographic Evidence for Isomeric Chromophores in 3‐Fluorotyrosyl‐Green Fluorescent Protein (2004) (20)
Thermococcus chitonophagus sp. nov., a novel, chitin-degrading, hyperthermophilic archaeum from a deep-sea hydrothermal vent environment (1995) (20)
Structure refinement of the aldehyde oxidoreductase from Desulfovibrio gigas (MOP) at 1.28 Å. (2001) (20)
Subunit composition, crystallization and preliminary crystallographic studies of the Desulfovibrio gigas aldehyde oxidoreductase containing molybdenum and [2Fe-2S] centers. (1993) (20)
Structure and evolution of the genetic code viewed from the perspective of the experimentally expanded amino acid repertoire in vivo (1999) (20)
Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments (2003) (20)
Biosynthesis of tetrahydrofolate in plants: crystal structure of 7,8-dihydroneopterin aldolase from Arabidopsis thaliana reveals a novel adolase class. (2004) (20)
Crystal structure of Escherichia coli inorganic pyrophosphatase complexed with SO4 2− (1997) (20)
Revealing nutritional requirements of MICP-relevant Sporosarcina pasteurii DSM33 for growth improvement in chemically defined and complex media (2020) (20)
Methyl-coenzyme M reductase and other enzymes involved in methanogenesis from CO2 and H2 in the extreme thermophile Methanopyrus kandleri (2004) (19)
Structure of lumazine protein, an optical transponder of luminescent bacteria. (2008) (19)
Structure of the complex of the antistasin-type inhibitor bdellastasin with trypsin and modelling of the bdellastasin-microplasmin system. (1999) (19)
A New Efficient Synthesis of Acetyltelluro- and Acetylselenomethionine and Their Use in the Biosynthesis of Heavy-Atom Protein Analogs (1996) (19)
12. SEA-SURFACE GRADIENTS BETWEEN THE NORTH ATLANTIC AND THE NORWEGIAN SEA DURING THE LAST 3.1 M.Y.: COMPARISON OF SITES 982 AND 985 1 (1999) (19)
Plasticity and steric strain in a parallel β‐helix: Rational mutations in the P22 tailspike protein (2000) (19)
The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study. (1999) (18)
Advanced online monitoring of cell culture off‐gas using proton transfer reaction mass spectrometry (2014) (18)
Phylum Al. Crenarchaeota phy. nov. (2001) (18)
The proton‐pumping NADH:ubiquinone oxidoreductase (complex I) of Aquifex aeolicus (2002) (18)
Elucidation of crystal packing by X-ray diffraction and freeze-etching electron microscopy. Studies on GTP cyclohydrolase I of Escherichia coli. (1995) (18)
PROTEASOME FROM THERMOPLASMA ACIDOPHILUM (1996) (18)
Crystal structure of 7,8-dihydroneopterin triphosphate epimerase. (1999) (18)
Proteinase — Protein inhibitor interactions (1994) (18)
Expression of alpha 1-proteinase inhibitor in Escherichia coli: effects of single amino acid substitutions in the active site loop on aggregate formation. (1994) (17)
The methyl group of N(alpha)(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage. (2002) (17)
Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond. (2005) (17)
ATP-independent DNA topoisomerase from Fervidobacterium islandicum. (1993) (17)
Kinetics and Inhibition of Recombinant Human Cystathionine γ-Lyase (1999) (17)
Influence of loop shortening on the metal binding site of cupredoxin pseudoazurin. (2007) (16)
STRUCTURAL STUDIES ON THE PANCREATIC TRYPSIN INHIBITOR – TRYPSIN COMPLEX AND ITS FREE COMPONENTS: STRUCTURE AND FUNCTION RELATIONSHIP IN SERINE PROTEASE INHIBITION AND CATALYSIS (1976) (16)
Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis. (2002) (16)
Crystal structures of modified apo-His117Gly and apo-His46Gly mutants of Pseudomonas aeruginosa azurin. (1997) (16)
Specific inhibition of insect alpha-amylases: yellow meal worm alpha-amylase in complex with the amaranth alpha-amylase inhibitor at 2.0 A resolution. (1999) (16)
X-Ray Crystal Structures of Human α-Thrombin and of the Human Thrombin-Hirudin Complex (1992) (16)
Mutations improving the folding of phage P22 tailspike protein affect its receptor binding activity. (1999) (16)
Hyperthermostabilization of Bacillus licheniformis alpha-amylase and modulation of its stability over a 50 degrees C temperature range. (2003) (16)
Electron microscopy of decorated crystals for the determination of crystallographic rotation and translation parameters in large protein complexes. (1992) (15)
Search for hyperhermophilic microorganisms in fluidsobtained from the KTB pump test (1994) (15)
Conversion of a regulatory into a degradative protease. (2010) (15)
Comparison of the NMR solution structure with the X-ray crystal structure of the activation domain from procarboxypeptidase B (1992) (15)
Role of electrostatic interaction in the stability of the hexamer of constitutive phycocyanin from Fremyella diplosiphon. (1991) (15)
Isolation, cloning, sequence analysis and localization of the operon encoding dimethyl sulfoxide/trimethylamine N-oxide reductase from Rhodobacter capsulatus. (1996) (15)
Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues (2018) (14)
The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism. (1989) (14)
The molybdenum site in the xanthine oxidase-related aldehyde oxidoreductase from Desulfovibrio gigas and a catalytic mechanism for this class of enzymes (1997) (14)
Structural transition of alpha 1-antitrypsin by a peptide sequentially similar to beta-strand s4A. (1990) (14)
Crystallization and crystallographic data of rabbit muscle phosphorylase a and b (1972) (13)
A polyunsaturated irregular acyclic C25 isoprenoid in a methanogenic archaeon (1997) (13)
Cloning, expression, crystallization and initial crystallographic analysis of the C-terminal domain of the amyloid precursor protein APP. (2004) (13)
Structure and function of the ion channel model system annexin V. (2006) (13)
Pancreatic procarboxypeptidases: their activation processes related to the structural features of the zymogens and activation segments. (1992) (13)
Molecular machines for protein degradation. Protein Degradation (2005) (13)
X-ray structures of free and leupeptin-complexed human alphaI-tryptase mutants: indication for an alpha-->beta-tryptase transition. (2006) (13)
Similarities of the heme environment in vertebrate and non‐vertebrate oxygen‐binding hemoproteins (1972) (13)
Crystallization of phycoerythrin 545 of Rhodomonas lens using detergents and unusual additives (1998) (12)
reply: Docking of components in a bacterial complex (2000) (12)
Cloning, purification, and crystallization of Escherichia coli cystathionine β‐lyase (1996) (12)
Crystallization and preliminary X-ray analysis of the tungsten-dependent acetylene hydratase from Pelobacter acetylenicus. (2005) (12)
Structural and Functional Consequences of Mutations in 6-Pyruvoyltetrahydropterin Synthase Causing Hyperphenylalaninemia in Humans PHOSPHORYLATION IS A REQUIREMENT FOR IN VIVO ACTIVITY* (1995) (12)
The substrate translocation channel of the proteasome. (2001) (12)
Life above the boiling point of water? (1986) (12)
Crystal structure of rat GTP cyclohydrolase I feedback regulatory protein, GFRP. (2001) (11)
Role of tachylectins in host defense of the Japanese horseshoe crab Tachypleus tridentatus. (2001) (11)
Substrate binding and catalysis by L-arginine:glycine amidinotransferase--a mutagenesis and crystallographic study. (1997) (11)
Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies (2021) (11)
L-Isoaspartate 115 of porcine beta-trypsin promotes crystallization of its complex with bdellastasin. (2000) (10)
Correlation of Amino Acid Sequence with Inhibitor Activity and Specificity of Protein Inhibitors of Serine Proteinases (1981) (10)
Incorporation of beta-selenolo[3,2-b]pyrrolyl-alanine into proteins for phase determination in protein X-ray crystallography. (2001) (10)
Screening for enzyme activity in turbid suspensions with scattered light (2011) (10)
Chemical Biology Approaches Reveal Conserved Features of a C‐Terminal Processing PDZ Protease (2012) (10)
Crystal structure and mechanism of action of the xanthine oxidase-related aldehyde oxidoreductase from Desulfovibrio gigas. (1997) (10)
Aerobic and Anaerobic Extremely Thermophilic Autotrophs (1987) (10)
Biochemical/spectroscopic characterization and preliminary X-ray analysis of a new aldehyde oxidoreductase isolated from Desulfovibrio desulfuricans ATCC 27774. (2000) (9)
Purification and crystallization of human anaphylatoxin, C3a. (1980) (9)
Male-male pairs in Greylag Geese (Anser anser) (1993) (9)
Structure of the molybdenum-cofactor biosynthesis protein MoaB of Escherichia coli. (2004) (9)
A novel, fully saturated cyclic menaquinone in the archaebacterium Pyrobaculum organotrophum (1991) (9)
CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST AT 2.4 ANGSTROMS RESOLUTION (1998) (8)
ZZE -Configuration of Chromophore β-153 in C-Phycocyanin from Mastigocladus laminosus (1987) (8)
STRUCTURE OF GLUTATHIONE S-TRANSFERASE (1997) (8)
The alpha-amylase from the yellow meal worm: complete primary structure, crystallization and preliminary X-ray analysis. (1997) (8)
Cutting at the right place--the importance of selective limited proteolysis in the activation of proproteinase E. (1998) (8)
The quaternary arrangement of HslU and HslV in a cocrystal: a response to Wang, Yale. (2001) (8)
Crystallographic evidence for structurally similar domains in the human kappa-type Bence-Jones protein Rei. (1972) (8)
Activation by substoichiometric inhibition (2020) (8)
Liposomes in assessment of annexin-membrane interactions. (2003) (8)
Pancreatic trypsin inhibitor (Kunitz). I. Structure and function. (1972) (8)
Structural Conservation and Functional Versatility: Allostery as a Common Annexin Feature (2003) (8)
The Atomic Structure of the Basic Trypsin Inhibitor of Bovine Organs. (Kallikrein Inactivator) (1971) (8)
corrigendum: Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine (2002) (7)
Structure and Properties of an Engineered Transketolase from Maize 1 Structure of Transketolase from Maize (2003) (7)
Structure and mechanism of GTP cyclohydrolase I of Escherichia coli. (1996) (7)
Crystallization and preliminary crystallographic characterization of GTP cyclohydrolase I from Escherichia coli. (1992) (7)
Herbicide detoxification by glutathione S-transferases as implicated from X-ray structures† (1999) (6)
[Crystal structure analysis of met-erythrocruorin at 5.5 Angstrom resolution]. (1968) (6)
Composition of Hydrothermal Vent Microbial Communities as Revealed by Analyses of Signature Lipids, Stable Carbon Isotopes and Aquificales Cultures (2001) (6)
Crystal Structure of cystathionine gamma-lyase from yeast (2002) (6)
Crystallization and preliminary X-ray crystallographic analysis of PdxJ, the pyridoxine 5'-phosphate synthesizing enzyme. (2000) (6)
Crystals of the NC1 domain of human type IV collagen. (1990) (6)
SYNTHASE/RIBOFLAVIN SYNTHASE COMPLEX OF BACILLUS SUBTILIS (1996) (6)
X-Ray Diffraction Analysis of Immunoglobulin Structure (1976) (6)
Class pi glutathione S-transferase from pig lung. Purification, biochemical characterization, primary structure and crystallization. (1991) (6)
Quantitative histological studies of the optic tectum in six species of Notropis and Cyprinella (Cyprinidae, Teleostei). (1991) (6)
Crystal structure of the soluble human Fc-gamma Receptor III (2000) (6)
Formation of metal nanoclusters on specific surface sites of protein molecules. (2002) (6)
Structural Investigations of the Highly Flexible Recombinant Ribosomal Protein L12 from Thermotoga maritima (2000) (5)
Crystal structure of 3,4-Dihydroxy-2-butanone 4-phosphate Synthase of Candida albicans (2004) (5)
The Ligand-induced Structural Changes of Humanl-Arginine:Glycine Amidinotransferase (1999) (5)
Pancreatic Trypsin Inhibitor (Kunitz) Part II: Complexes with Proteinases (1972) (5)
Proceedings: X-ray diffraction analysis of immunoglobulin structure. (1976) (5)
Oxygen-dependent coproporphyrinogen-III oxidase from Escherichia coli: one-step purification and biochemical characterisation. (2003) (5)
Sensitivity of ribosomes of the hyperthermophilic bacterium Aquifex pyrophilus to aminoglycoside antibiotics (1996) (4)
The Structure of the Photochemical Reaction Center of Rhodopseudomonas viridis and Its Implications for Function (1989) (4)
[22] X-ray structure methods for glutathione binding (1995) (4)
The 1 . 8 Angstrom Crystal Structure of an MMP 8-Barbiturate Inhibitor Complex Reveals a Previously Unobserved Mechanism for Collagenase Substrate Recognition (2001) (4)
Expression of wild-type and mutated Drosophila melanogaster xanthine dehydrogenases in Aspergillus nidulans. (1997) (4)
Influence of Initial pH Values on the Lag Phase of Escherichia coli and Bacillus licheniformis Batch Cultures (2013) (4)
Interaction between Chymotrypsin (Trypsin) and the Pancreatic Trypsin Inhibitor (Kallikrein Inactivator) (1972) (4)
Varshavsky's Contributions (2004) (4)
Design, Synthesis, and Biological Evaluation of Quercetagetin Analogues as JNK1 Inhibitors. (2015) (4)
Tobacco uroporphyrinogen-III decarboxylase: characterization, crystallization and preliminary X-ray analysis. (2001) (4)
Aldheyde oxidoreductase from D. gigas contains a molybdopterin cytosine dinucleotide (1995) (4)
Site-directed mutagenesis and structural interpretation of the nidogen binding site of the laminin γl chain (1997) (4)
Serpin structures. (1993) (4)
pH-induced structural change in erythrocruorin. (1971) (3)
BACILLUS LICHENIFORMIS ALPHA-AMYLASE (1999) (3)
Caspase activator human granzyme B, crystal structure and implications in apoptosis (2002) (3)
The 2.0 A crystal structure of the KDEL-tailed cysteine endopeptidase functioning in programmed cell death of Ricinus communis endosperm (2004) (3)
Synthesis, Kinetic Characterization and X-Ray Analysis of Peptide Aldehydes as Inhibitors of the 20S Proteasomes from Thermoplasma acidophilum and Saccharomyces cerevisiae (1997) (3)
Tectonic stress in the southwestern Arabian shield (1986) (3)
CARBON MONOXIDE DEHYDROGENASE FROM HYDROGENOPHAGA PSEUDOFLAVA (2000) (3)
Structural Basis of Fosmidomycin Action revealed by the Complex with IspC: Implications for the Catalytic Mechanism and Anti-Malaria Drug Development (2003) (3)
X-ray structure methods for glutathione binding. (1995) (2)
"How I chose research on proteases or, more correctly, how it chose me". (2013) (2)
4-Hydroxyphenylpyruvate Dioxygenase (2004) (2)
Crystallographic studies and biochemical characterization of the desulfovibrio gigas aldehyde oxido-reductase, an enzyme containing a molybdopterin co-factor and two [2FE-2S] centers (1993) (2)
X-Ray Crystallography of Biological Macromolecules (2000) (2)
Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation (2010) (2)
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Conformational Epitope Region in Rodents Response Is Focused on One Dominant Glycoprotein-Specific Autoantibody Demyelinating Myelin Oligodendrocyte (2008) (2)
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CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN L4 (2000) (2)
X-ray crystallographic characterisation of type-2 depleted ascorbate oxidase from zucchini (1991) (2)
Advanced off-gas measurement using proton transfer reaction mass spectrometry to predict cell culture parameters (2013) (2)
Acold-loving crenarchaeon is a substantial partofa novelmicrobial community in cold sulphidicmarshwater (2006) (2)
Crystal structure of uninhibited factor VIIa (2002) (2)
Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair (2020) (2)
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Crystal structure of 12-oxophytodienoate reductase 3 (OPR3) from tomato (2001) (2)
Carbon and carbonate concentrations of recent and Pleistocene sediments of the Norwegian-Greenland Sea (2000) (2)
Cyclic biphenyl ether tripeptides as proteasome inhibitors (2003) (1)
DPP9 bound to a dipeptide (MP) from the N-terminus of BRCA2 (2020) (1)
Structure of a multicopper protein: Ascorbate oxidase (1989) (1)
Crystal structure of the tricorn protease (2001) (1)
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3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii (2004) (1)
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CRYSTAL STRUCTURE OF THE CYSTINE C-S LYASE C-DES (2000) (1)
PEPTIDYL-CYSTEINE DECARBOXYLASE EPID (2001) (1)
Modeling the intact form of the alpha 1-proteinase inhibitor. (1990) (1)
Corrigendum to "Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side Chain to Selectivity" (Journal of Molecular Biology, vol 371, pg 989, 2007) (2009) (1)
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ATP SULFURYLASE FROM S. CEREVISIAE (2001) (1)
Studies on the Reaction Mechanism of GTP Cyclohydrolase I (2002) (1)
REFINED CRYSTAL STRUCTURE OF ASCORBATE OXIDASE AT 1.9 ANGSTROMS RESOLUTION (1993) (1)
Crystal structure of NusA from Thermotoga maritima (2001) (1)
2 The Refined X-Ray Crystal Structures of Human and Rat Liver Cathepsin B (1994) (1)
Structural analysis at 2.2 Å of orthorhombic crystals presents the asymmetry of the allophycocyanin-linker complex, APzL C , from phycobilisomes of Mastigocladus laminosus (cyanobacteriaylinker polypeptidesycrystallizationyphotosynthesisyenergy transfer) (1999) (1)
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Electron microscopy and X-ray diffraction studies on heavy riboflavin synthase from Bacillus subtilis (1984) (1)
7,8-DIHYDRONEOPTERIN TRIPHOSPHATE EPIMERASE (2000) (1)
CYSTATHIONINE GAMMA-SYNTHASE FROM NICOTIANA TABACUM (1999) (1)
CRYSTAL STRUCTURE OF THE MT1-MMP--TIMP-2 COMPLEX (1999) (1)
CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V (1999) (1)
Crystal structure of the thermostable serine-carboxyl type proteinase, kumamolisin (KSCP) - complex with Ac-Ile-Ala-Phe-cho (2002) (1)
Human b-tryptase isa ring-like tetramerwithactive sites facingacentral pore (1)
CRYSTAL STRUCTURE OF SOLUBLE HUMAN IGG1 FC FRAGMENT-FC-GAMMA RECEPTOR III COMPLEX (2000) (1)
Crystal structure of DPP8 in complex with the EIL peptide (SLRFLFEGQRIADNH) (2021) (0)
Intracellular protease machines, structures, mechanisms and drug development (2012) (0)
The molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-A resolution. (1975) (0)
Crystal structure of human CDK8/CYCC in complex with compound 1 (N-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-4-[2-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)ethyl]piperazine-1-carboxamide) (2013) (0)
COMPLEX OF 3-MERCAPTO-2-BENZYLPROPANOYL-ALA-GLY-NH2 WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) (1996) (0)
Crystal structure of F1-mutant S105A complex with PCK (2005) (0)
STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D70N (1997) (0)
Phosphopantothenoylcysteine synthetase from E. coli (2004) (0)
CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI (1998) (0)
alpha-ring from the proteasome from archaeoglobus fulgidus (2003) (0)
3,4-dihydroxy-2-butanone 4-phosphate synthase from M. jannaschii (2003) (0)
E.coli NAD Synthetase, DND (2005) (0)
Maximum diameter of Neogloboquadrina pachyderma sinistral from surface sediment samples from the Norwegian-Greenland Sea (2019) (0)
Crystal structure of human CDK8/CYCC in complex with compound 5 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[3-(morpholin-4-yl)propyl]urea) (2013) (0)
Crystal structure of the yeast 20S proteasome in complex with ligand 2c (2011) (0)
The Crystal Structure of Allophycocyanin and Its Comparison to C-Phycocyanin and b-Phycoerythrin (1996) (0)
PIG ALPHA-AMYLASE (1996) (0)
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE, DELETIONMUTANT ATDELTAM302 (1999) (0)
Technologietransfer Ausgründung: SuppreMol GmbH – Innovationen kann man nicht planen. (2009) (0)
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Porcine dipeptidyl peptidase IV (CD26) in complex with 7-Benzyl-1,3-dimethyl-8-piperazin-1-yl-3,7-dihydro-purine-2,6-dione (BDPX) (2006) (0)
Structural determinants for 20S proteasome inhibition by TMC-95A (2005) (0)
Crystal Structure and Mechanism of the Xanthine Oxidase-Related Aldehyde Oxido-Reductase from D. gigas (1997) (0)
PORCINE FACTOR IXA (1996) (0)
E.coli NAD Synthetase (2005) (0)
CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT (E.C.2.7.1.37) (PROTEIN KINASE A) COMPLEXED WITH PROTEIN KINASE INHIBITOR PEPTIDE FRAGMENT 5-24 (PKI(5-24) ISOELECTRIC VARIANT CA) AND MN2+ ADENYLYL IMIDODIPHOSPHATE (MNAMP-PNP) AT PH 5.6 AND 7C AND 4C (1995) (0)
Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 8 (2005) (0)
Structure of the unliganded form of the proprotein convertase furin. (2016) (0)
(Table 3) Morphometric measurements of Neogloboquadrina pachyderma sin. from ODP Site 151-909 in the Fram Strait (2000) (0)
GLUTATHIONE S-TRANSFERASE I FROM MAIS IN COMPLEX WITH ATRAZINE GLUTATHIONE CONJUGATE (1998) (0)
A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation (2005) (0)
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Proteases and their regulation - from structures to mechanisms and new concepts for intervention (2005) (0)
CRYSTAL STRUCTURE OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE (2001) (0)
Structure of 6,7-Dimthyl-8-ribityllumazine synthase from Schizosaccharomyces pombe mutant W27Y with bound ligand 6-carboxyethyl-7-oxo-8-ribityllumazine (2005) (0)
Porcine dipeptidyl peptidase IV (CD26) in complex with the tripeptide tert-butyl-Gly-L-Pro-L-Ile (tBu-GPI) (2006) (0)
High-resolution crystal structure of C-Phycocyanin and polarized optical spectra of single crystals (1988) (0)
(Table 3) Morphometric measurements of Neogloboquadrina pachyderma sin. from ODP Site 151-907 on the Iceland Plateau (2000) (0)
COMPLEX OF BDELLASTASIN WITH PORCINE TRYPSIN (2000) (0)
PIG PANCREATIC ALPHA-AMYLASE COMPLEXED WITH THE OLIGOSACCHARIDE V-1532 (1996) (0)
A pharmaceutical composition comprising sFcRgamma IIb or III sFcRgamma (2001) (0)
Crystal Structure of human CDK8/CycC (2011) (0)
Methanopyraceae fam. nov. (2015) (0)
Crystal Structure of Protoporphyrinogen IX Oxidase (2004) (0)
The Crystal and Molecular Structure of C-Phycocyanin (1985) (0)
nov . , a new genus of hyperthermophilic archaea isolated after i ts prediction from environmentally derived 16 s rRNA sequences (2008) (0)
Crystal structure of human CDK8/CYCC in complex with compound 2 (tert-butyl [3-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)propyl]carbamate) (2013) (0)
Crystal Structure of Threonine Synthase from Yeast (2002) (0)
Structure of A Catalytically Inactive Mutant (K223A) of C-DES with a Substrate (Cystine) Linked to the Co-Factor (2003) (0)
TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C (1997) (0)
Novel aspects of copper (azorin and ascorbate oxidase) and zink proteins (procarboxypeptidase) and the structure of a calcium, membrane binding protein (annexin). (1991) (0)
Crystal structure of Src kinase domain (2006) (0)
Complexes of the proteolytic machinery from Thermoplasma acidophilum (2004) (0)
The2.0A X-raycrystal structure ofchicken egg white cystatin anditspossible modeofinteraction with cysteine proteinases (1988) (0)
DUAL BINDING MODE OF BISINDOLYLMALEIMIDE 2 TO PROTEIN KINASE A (PKA) (2004) (0)
HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues (2010) (0)
Crystal structure of Src kinase domain in complex with CGP77675 (2006) (0)
Structural and functional studies of the yeast class II Hda1 HDAC complex (2009) (0)
The Three-Dimensional Structure of Allophycocyanin (1995) (0)
(Table 3) Morphometric measurements of Neogloboquadrina pachyderma sin. from ODP Site 162-985 in the Norway Basin (2000) (0)
PKA triple mutant model of PKB (2003) (0)
Cutting complexity down to size: Structural and mutational studies of the eukaryotic 20S proteasome (2000) (0)
Crystal Structure of the Carboxypeptidase A from Helicoverpa Armigera (2002) (0)
TAILSPIKE PROTEIN, MUTANT A334I (2000) (0)
Crystal Structure of DegP (HtrA) (2002) (0)
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Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition (2011) (0)
X-RAY Structure of 2,5-diamino-6-ribosylamino-4(3h)-pyrimidinone 5-phosphate reductase (2006) (0)
Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 4 (2005) (0)
Phosphopantothenoylcysteine synthetase from E. coli, CMP complex (2004) (0)
X-raySnapshotsofPeptideProcessinginMutantsof Tricorn-interactingFactorF1fromThermoplasmaacidophilum * (2005) (0)
Crystal structure of active site F1-mutant Y205F complex with inhibitor PCK (2005) (0)
Crystal structure of the thrombin-thrombomodulin complex (2000) (0)
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Structure the proprotein convertase furin in complex with meta-guanidinomethyl-Phac-RVR-Amba at 2.0 Angstrom resolution. (2016) (0)
Crystal structures of recombinant wild-type azurin from Pseudomonas aeruginosa and site-specific mutants (1991) (0)
Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 5 (2005) (0)
UROKINASE PLASMINOGEN ACTIVATOR B-CHAIN INHIBITOR COMPLEX (2000) (0)
Crystal structure of a human IgG1 Fc-fragment,high salt condition (2003) (0)
COMPLEX BETWEEN THE CYSTINE C-S LYASE C-DES AND ITS REACTION PRODUCT CYSTEINE PERSULFIDE. (2000) (0)
CRYSTAL STRUCTURE OF ANNEXIN 24(CA32) FROM CAPSICUM ANNUUM (2000) (0)
Domain truncation, point mutation, and surrogation for structure based kinase inhibitor design (2005) (0)
Phosphopantothenoylcysteine synthetase from E. coli, 4'-phosphopantothenoyl-CMP complex (2004) (0)
N-glycosylation of the Fc-fragment of human IgG1 is crucial for its structural integrity and Fcg-receptor affinity (2002) (0)
Aerobic and anaerobic life on carbon monoxide (2003) (0)
Table of Contents (1991) (0)
Correction for Sitar et al., Molecular architecture of the Spire–actin nucleus and its implication for actin filament assembly (2016) (0)
DPP8 - SLRFLYEG, space group 19 (2018) (0)
STRUCTURE OF CDK INHIBITOR P19INK4D (1998) (0)
Crystal Structure of the Tricorn Interacting Factor F1 Complex with PCK (2002) (0)
Cofactor-and substrate-assisted activation of factor VIIa (2002) (0)
Table of Contents (1991) (0)
Crystal structure of Aquifex aeolicus N-utilization substance G (NusG), Space group I222 (2003) (0)
Carbon and carbonate concentrations of ODP Hole 162-985A in the Norwegian-Greenland Sea (2000) (0)
Crystal structure of Isoaspartyl Dipeptidase (2004) (0)
CRYSTAL STRUCTURE OF CYSTALYSIN FROM TREPONEMA DENTICOLA CONTAINS A PYRIDOXAL 5'-PHOSPHATE COFACTOR (2000) (0)
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A Real-space Electron Crystallographic Method for Elucidation of Crystal Packing of a Large, Symmetric Protein Complex (1992) (0)
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ATP SULFURYLASE FROM S. CEREVISIAE: THE TERNARY PRODUCT COMPLEX WITH APS AND PPI (2001) (0)
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Queen Honeybee and Me: Forever Young? Conserved Pathways for Longevity (2013) (0)
The Turkwel hydropower project near the Kenyan Rift Valley (East Africa) (1990) (0)
Table of Contents (1996) (0)
GLUTATHIONE S-TRANSFERASE IN COMPLEX WITH MEISENHEIMER COMPLEX (1998) (0)
STRUCTURE OF PORCINE TRYPSIN COMPLEXED WITH BDELLASTASIN, AN ANTISTASIN-TYPE INHIBITOR (2001) (0)
Crystal Structure of an archaeal pentameric riboflavin synthase Complex with a Substrate analog inhibitor (2005) (0)
STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D65N (1997) (0)
Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Dithionite reduced state (2002) (0)
CRYSTAL STRUCTURE OF DESULFOREDOXIN FROM DESULFOVIBRIO GIGAS AT 1.8 A RESOLUTION (1997) (0)
MACDONALD SEAMOUNT (*) (28゜59'S, 140゜15'W) South Central Pacific (1994) (0)
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CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI IN COMPLEX WITH AMINOETHOXYVINYLGLYCINE (1998) (0)
STRUCTURE OF LIGHT HARVESTING COMPLEX OF ALLOPHYCOCYANIN ALPHA AND BETA CHAINS/CORE-LINKER COMPLEX AP*LC7.8 (1999) (0)
(Table 3) Morphometric measurements of Neogloboquadrina pachyderma sin. from ODP Site 104-643 on the outer Voring Plateau (2000) (0)
BOVINE THROMBIN--BM14.1248 COMPLEX (1997) (0)
20S proteasome in complex with calpain-Inhibitor I from archaeoglobus fulgidus (2003) (0)
Pseudoazurin with engineered amicyanin ligand loop, oxidized form, pH 5.5 (2007) (0)
Lumazine Synthase from S.pombe bound to carboxyethyllumazine (2002) (0)
Crystal Structure of MMP8-Barbiturate Complex Reveals Mechanism for Collagen Substrate Recognition (2001) (0)
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Huber, R.; Sondermann, P.; Jacob, U.; Wendt, K.; Chiara, C.; Moroder, L. Substance binding human Igg FC Receptor IIB (FCYRIIB). US Patent: US 08853363 (2014) (0)
High resolution analysis of proteolytic substrate processing (2022) (0)
The Thermotogales: Hyperthermophilic and Extremely Thermophilic Bacteria (2021) (0)
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PKA double mutant model of PKB (2003) (0)
Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Cyanide-inactivated Form (2002) (0)
PKA double mutant model of PKB in complex with MgATP (2003) (0)
CRYSTAL STRUCTURE OF GLUTACONATE COENZYME A-TRANSFERASE FROM ACIDAMINOCOCCUS FERMENTANS TO 2.55 ANGSTOMS RESOLUTION (1998) (0)
A withproproteinase Eand chymotrypsinogen C (1995) (0)
Protein kinase A variant complex with completely ordered N-terminal helix (2004) (0)
Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 1 (2005) (0)
Crystal structure of inactive F1-mutant G37A (2005) (0)
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CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH ALPHA-AMINO BUTYRIC ACID (1999) (0)
Table of Contents (1995) (0)
TETRAMERIC RESTRICTION ENDONUCLEASE NGOMIV IN COMPLEX WITH CLEAVED DNA (2001) (0)
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH L-NORVALINE (1999) (0)
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Crystal Structure of the Tricorn Interacting Factor F1 (2002) (0)
How to achieve reproducible inocula in shaken bioreactors (2012) (0)
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CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN L12 FROM THERMOTOGA MARITIMA (2000) (0)
Table of Contents (1995) (0)
Crystal structure of F1-mutant S105A complex with PHE-LEU (2005) (0)
Crystalline, in the asymmetric unit at least one involved in catalysis (Sub) -Domaine a human m-calpain, exhibiting polypeptide, methods for identifying compounds by using the same, processes for the crystallization and method for displaying a 3-dimensional structure of this peptide (1999) (0)
pyrophilus to aminoglycoside antibiotics. hyperthermophilic bacterium Aquifex Sensitivity of ribosomes of the (2013) (0)
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Crystal structure of HslV from Thermotoga maritima (2003) (0)
Targeted grazing of slopes and alpine meadows. (2010) (0)
Table of Contents (1996) (0)
DPP8 bound to a dipeptide (MP) from the N-terminus of BRCA2 (2020) (0)
Quantitative neuroanatomical studies of minnows in Notropis and related genera (Cyprinidae, Teleostei), with emphasis on the visual system (1989) (0)
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Annexin V: Analysis of mutants of a voltage-gated calcium channel (1993) (0)
Structural basis for a NusA- protein N interaction (2004) (0)
CO DEHYDROGENASE FROM OLIGOTROPHA CARBOXIDOVORANS (1999) (0)
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BOVINE THROMBIN--BM12.1700 COMPLEX (1997) (0)
Table of Contents (1996) (0)
Structural implications for substrate binding byPyrococcus furiosusDNA primase (2002) (0)
COAGULATION FACTOR XA-TRYPSIN CHIMERA INHIBITED WITH D-PHE-PRO-ARG-CHLOROMETHYLKETONE (1998) (0)
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A method for identifying inhibitors of 20S and 26S proteasome (2002) (0)
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Crystal structure of 7,8-dihydroneopterin aldolase in complex with guanine (2004) (0)
CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH STAUROSPORINE (1998) (0)
Shell size variation of Neogloboquadrina pachyderma sin. in the Norwegian-Greenland Sea during the last 1.3 Myr (2000) (0)
CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V: DIMERIC CRYSTAL FORM (1999) (0)
STRUCTURE OF TAILSPIKE-PROTEIN (1997) (0)
THERMOSOME FROM T. ACIDOPHILUM (1999) (0)
MrsD from Bacillus sp. HIL-Y85/54728 (2003) (0)
CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PROTEIN S (2000) (0)
STRUCTURE OF SERINE PROTEINASE (1997) (0)
Crystal structure of the E291K mutant of 12-oxophytodienoate reductase 3 (OPR3) from tomato (2006) (0)
CRYSTAL STRUCTURE OF ZINC-CONTAINING E.COLI GTP CYCLOHYDROLASE I (2001) (0)
Inhibition of yeast 20S proteasome by biaryl- and biaryl ether cross-bridged tripeptide derivatives as TMC-95A analogs (2005) (0)
Crystal Structure of Human m-Calpain Form II (2001) (0)
CRYSTAL STRUCTURE OF HUMAN GTP CYCLOHYDROLASE I (2000) (0)
Structure of 6,7-Dimethyl-8-ribityllumazine synthase from Schizosaccharomyces pombe mutant W27Y with bound riboflavin (2005) (0)
HYDROGENASE MATURATING ENDOPEPTIDASE HYBD FROM E. COLI (2000) (0)
CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN (2003) (0)
SUBLACUSTRINE HYDROTHERMAL ACTIVITY AND MASSIVE SULFIDES FROM THE NORTH TANGANYIKA TROUGH, EAST-AFRICAN RIFT - 1991 TANGANYDRO EXPEDITION. (1992) (0)
Crystal Structure of an archaeal pentameric riboflavin synthase (2005) (0)
CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR CTCPO (2001) (0)
X-ray structure of clotting factor IXa: Active site and module structure related to Xase activity and hemophilia B (x-ray (2005) (0)
Crystal structure of DPP8 in complex with 1G244 (2021) (0)
STRUCTURE OF CHICKEN ANNEXIN V AT 2.25-ANGSTROMS RESOLUTION (1993) (0)
Enzyme-analogue substrate complex of Pyridoxine 5'-Phosphate Synthase (2003) (0)
Structural insights into the multiple sclerosis autoantigen myelin oligodendrocyte glycoprotein and its complex with a pathogenic autoantibody (2004) (0)
Mutant enzyme W63Y/L119F Lumazine Synthase from S.pombe (2002) (0)
Crystal structure of human CCA-adding enzyme (2003) (0)
Enzyme-Phosphate2 Complex of Pyridoxine 5'-Phosphate synthase (2003) (0)
Supporting Information for Crystallographic Evidence For Chromophore Isomerisation In 3-Fluorotyrosyl-Green Fluorescent Protein (2003) (0)
TAILSPIKE PROTEIN FROM PHAGE P22, V331A MUTANT (1999) (0)
PIG PANCREATIC ALPHA-AMYLASE IN COMPLEX WITH THE PROTEINACEOUS INHIBITOR TENDAMISTAT (1998) (0)
tricorn protease in complex with a tridecapeptide chloromethyl ketone derivative (2002) (0)
Table of Contents (1993) (0)
Structure of bovine pancreatic trypsin inhibitor: joint refinement with high-resolution X-ray and neutron data (1984) (0)
Crystallographic studies of 12-oxophytodienoate reductases from tomato (2002) (0)
HUMAN FC GAMMA RECEPTOR IIB ECTODOMAIN (CD32) (2000) (0)
BOVINE THROMBIN--BM51.1011 COMPLEX (1997) (0)
Tryptophan analogues into proteins, peptides and peptide lead compounds (2000) (0)
E.coli NAD Synthetase, AMP (2005) (0)
GLUTATHIONE S-TRANSFERASE IN COMPLEX WITH P-BROMOBENZYLGLUTATHIONE (1997) (0)
Crystal structure of the Y364F mutant of 12-oxophytodienoate reductase 3 from tomato (2006) (0)
Crystal Structure of the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans (2003) (0)
Structure at 2.25Å resolution of the aldehyde oxido-reductase from Desulfovibrio gigas, a member of the xanthine oxidase protein family containing molybdopterin and iron-sulfur centers (1995) (0)
The Catalytic Subunit of cAMP-dependent Protein Kinase (PKA) in Complex with Rho-kinase Inhibitor Y-27632 (2003) (0)
GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP (1999) (0)
THERMOSTABLE B TYPE DNA POLYMERASE FROM THERMOCOCCUS GORGONARIUS (1999) (0)
Crystal structure of the thermostable serine-carboxyl type proteinase, kumamolysin (kscp) (2002) (0)
CRYSTAL STRUCTURE OF HSLV (CLPQ) AT 3.8 ANGSTROMS RESOLUTION (1998) (0)
Crystal structures of the Tricorn interacting Factor F3 from Thermoplasma acidophilum (2005) (0)
FIGHT STRATEGIES DIFFERWITH SIZE ANDALLOMETRIC GROWTHOF CLAWS IN CRAYFISH , ORCONECTESRUSTICUS (2004) (0)
Crystal structure of active site F1-mutant E213Q soaked with peptide Pro-Leu-Gly-Gly (2005) (0)
Crystal structure of yeast 20S proteasome in complex with ligand 2a (2011) (0)
DPP8 - Apo, space group 20 (2018) (0)
Improvement of the structure determination of biological aggregates in the X-ray crystallography (1997) (0)
Crystal Structure of 3,4-Dihydroxy-2-butanone 4-phosphate Synthase of Candida albicans in complex with Ribulose-5-phosphate (2004) (0)
CRYSTAL STRUCTURE OF CYSTALYSIN FROM TREPONEMA DENTICOLA CONTAINS A PYRIDOXAL 5'-PHOSPHATE-L-AMINOETHOXYVINYLGLYCINE COMPLEX (2000) (0)
LE (LAMININ-TYPE EGF-LIKE) MODULE GIII4 IN SOLUTION AT PH 3.5 AND 290 K, NMR, 14 STRUCTURES (1997) (0)
INOSAMINE-PHOSPHATE AMIDINOTRANSFERASE STRB1 FROM STREPTOMYCES GRISEUS (1999) (0)
156 Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single chain human tPA and vampire bat plasminogen activator (1997) (0)
Maize Transketolase in complex with TPP (2003) (0)
Secreted aspartic proteinase (Sap) 3 from Candida albicans (2007) (0)
Table of Contents (1996) (0)
CRYSTAL STRUCTURE OF 12-OXOPHYTODIENOATE REDUCTASE 1 FROM TOMATO COMPLEXED WITH 9R,13R-OPDA (2001) (0)
IspC apo structure (2003) (0)
Proteasome in complex with hydroxyurea derivative HU10 (2011) (0)
Maximum diameter of Neogloboquadrina pachyderma sinistral of ODP Hole 162-987D in the Norwegian-Greenland Sea (2000) (0)
DPP8 - SLRFLYEG, space group 20 (2018) (0)
CRYSTAL STRUCTURE OF THE ALDEHYDE OXIDOREDUCTASE FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 (2000) (0)
Convergent Synthesis and Biological Evaluation of Syringolin A and Derivatives as Eukaryotic 20S Proteasome Inhibitors (Eur. J. Org. Chem. 21/2010) (2010) (0)
Multiple Conformations of Cystatin, Mung Bean Inhibitor, and Serpins (1994) (0)
Serines proteases chimeres (1998) (0)
Hyperthermophilic Bacterial Communities within Terrestrial and Marine Hydrothermal Areas (1989) (0)
High-throughput experimentation for microscale cultivations and recombinant protein expression (2010) (0)
Human alpha1-tryptase (2003) (0)
This interaction seems to be largely independent of the structure or sequence of the substrate proteins (1998) (0)
Structure of SdaI restriction endonuclease (2006) (0)
Structure of CAMP-dependent protein kinase, alpha-catalytic subunit in complex with H8 protein kinase inhibitor [N-(2-methylamino)ethyl]-5-isoquinolinesulfonamide (1997) (0)
STRUCTURE OF GLUTATHIONE S-TRANSFERASE III IN APO FORM (1998) (0)
Crystal structure of the yeast 20S proteasome in complex with 2b (2011) (0)
(Table 3) Morphometric measurements of Neogloboquadrina pachyderma sin. from ODP Site 162-987 on the Greenland Margin (2000) (0)
The Crystal Structure of the p130Cas SH3 Domain at 1.1 A Resolution (2005) (0)
CRYSTAL STRUCTURE OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE IN COMPLEX WITH PYRIDOXINE 5'-PHOSPHATE AND INORGANIC PHOSPHATE (2001) (0)
Porcine dipeptidyl peptidase IV (CD26) in complex with L-Pro-boro-L-Pro (boroPro) (2006) (0)
Agent tryptase inhibitors. (1999) (0)
Structure of the aldehyde oxidoreductase fromDesulfofibrio gigas: a member of the xanthine oxidase protein family (1996) (0)
The Catalytic Subunit of cAMP-dependent Protein Kinase in Complex with Rho-kinase Inhibitor Fasudil (HA-1077) (2003) (0)
Crystal structure of human MMP-12 (Macrophage Elastase) at true atomic resolution (2001) (0)
Crystal structure of Pseudomonas aeruginosa apo-azurin at resolution (1992) (0)
MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND SEPIAPTERIN (1999) (0)
A Polyunsaturated Irregular Acyclic C25 Isoprenoid in a Methanogenic Archaeon. (1997) (0)
Lumazine Synthase from S.pombe bound to nitropyrimidinedione (2002) (0)
DPP8 - Apo, space group 19 (2018) (0)
Complex of IGFBP-5 with IGF-I (2002) (0)
HUMAN ANNEXIN V WITH PROLINE SUBSTITUTION BY THIOPROLINE (1998) (0)
Secreted aspartic proteinase (Sap) 1 from Candida albicans (2008) (0)
Isoaspartyl Dipeptidase with bound inhibitor (2004) (0)
TACHYLECTIN 5A FROM TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB) (1999) (0)
STRUCTURE OF OXIDOREDUCTASE (NADP+(A),FERREDOXIN(A)) (1996) (0)
IspC Mn2+ complex (2003) (0)
THROMBIN INHIBITOR FROM TRIATOMA PALLIDIPENNIS (1998) (0)
The thermostable serine-carboxyl type proteinase, kumamolisin (KSCP) - complex with Ac-Ile-Pro-Phe-cho (2002) (0)
High Resolution Crystal Structure of Mutant W129A of Kumamolisin, a Sedolisin Type Proteinase (previously called Kumamolysin or KSCP) (2004) (0)
Crystal structure of the yeast 20S proteasome in complex with syringolin B (2009) (0)
Myelin Oligodendrocyte Glycoprotein-(8-18C5) Fab-complex (2003) (0)
Crystal Structure of the Mo,Cu-CO Dehydrogenase (CODH), n-butylisocyanide-bound state (2002) (0)
Crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV: Stabilization via a novel type of covalent Met-Lys cross-link (2002) (0)
Crystal Structure of ATP Sulfurylase in complex with ADP (2001) (0)
GLUTATHIONE S-TRANSFERASE IN COMPLEX WITH GLUTATHIONE (1998) (0)
Crystal structure of pepV (2002) (0)
E.coli NAD Synthetase, AMP.PP (2005) (0)
Lumazine Synthase from S.pombe bound to riboflavin (2002) (0)
Methanopyrales ord. nov (2015) (0)
University of Groningen 2,6,10,15,19-Pentamethylicosenes in Methanolobus bombayensis, a marine methanogenic archaeon, and in Methanosarcina mazei VanderMaarel, (2003) (0)
Crystal structure of MoaB from Escherichia coli (2004) (0)
MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND OXALOACETATE (1999) (0)
Crystal Structure of the Recombinant Human Alpha I Tryptase Mutant K192Q/D216G in Complex with Leupeptin (2006) (0)
STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH H89 PROTEIN KINASE INHIBITOR N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE (1997) (0)
Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Carbon monoxide reduced state (2002) (0)
COMPLEX OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR WITH PORCINE TRYPSIN (1998) (0)
Structural and functional analysis of quercetagetin, a natural JNK1 inhibitor (2012) (0)
Secreted aspartic proteinase (Sap) 5 from Candida albicans (2008) (0)
Crystal structure of C19A/C43A mutant of leech carboxypeptidase inhibitor in complex with bovine carboxypeptidase A (2006) (0)
TITLE OF TAILSPIKE-PROTEIN (1997) (0)
NIFS-LIKE PROTEIN (2000) (0)
STRUCTURE OF TENEBRIO MOLITOR LARVAL ALPHA-AMYLASE (1998) (0)
SEPIAPTERIN REDUCTASE COMPLEXED WITH N-ACETYL SEROTONIN (1999) (0)
Crystal Structure of ATP Sulfurylase in complex with thiosulfate (2001) (0)
Annexin V: Structure-function analysis of a voltage-gated, calcium-selective ion channel (1995) (0)
Crystal structure of DESC1, a new member of the type II transmembrane serine proteinases family (2007) (0)
CRYSTAL STRUCTURE OF THE HUMAN IGG1 FC-FRAGMENT,GLYCOFORM (M3N2F)2 (2003) (0)
Structures of the Yeast Proteasome Core Particle in Complex with Inhibitors (2004) (0)
Summary of foraminifer and ice rafted debris counts from ODP Site 162-985 (2017) (0)
ATP SULFURYLASE FROM S. CEREVISIAE: THE BINARY PRODUCT COMPLEX WITH APS (2001) (0)
Carbon and carbonate concentrations of ODP Hole 162-987D in the Norwegian-Greenland Sea (2000) (0)
Crystal Structure of the Tricorn Interacting Factor Selenomethionine-F1 (2002) (0)
Hydrogenase maturation endopeptidase (2004) (0)
Determination of nutritional requirements of calcite precipitating Sporosarcina pasteurii to increase biomass yield for biocementation (2020) (0)
ACTIN-FRAGMIN KINASE, CATALYTIC DOMAIN FROM PHYSARUM POLYCEPHALUM (1999) (0)
CRYSTAL STRUCTURE OF THE ABERRANT BA3-CYTOCHROME-C OXIDASE FROM THERMUS THERMOPHILUS (2001) (0)
IspC complex with Mn2+ and fosmidomycin (2003) (0)
CRYSTAL STRUCTURE OF A NI-CONTAINING CARBON MONOXIDE DEHYDROGENASE FROM CARBOXYDOTHERMUS HYDROGENOFORMANS (2001) (0)
HUMAN COAGULATION FACTOR IXA IN COMPLEX WITH P-AMINO BENZAMIDINE (1999) (0)
The crystal structure of the carboxytransferase subunit of glutaconyl-CoA decarboxylase (2002) (0)
STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D97N (1997) (0)
CRYSTAL STRUCTURE OF OXIDIZED CYTOCHROME C6 FROM THE GREEN ALGAE SCENEDESMUS OBLIQUUS (2000) (0)
JAPANESE HORSESHOE CRAB COAGULOGEN (1997) (0)
IPP:DMAPP isomerase type II apo structure (2003) (0)
CYTOCHROME C NITRITE REDUCTASE FROM WOLINELLA SUCCINOGENES-SULFATE COMPLEX (2001) (0)
CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V: COMPLEX WITH PHENYLMERCURY (1999) (0)
Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) (2003) (0)
Ascaris suum carboxypeptidase inhibitor in complex with human carboxypeptidase A1 (2008) (0)
The Bowman-Birk type inhibitor from mung bean in ternary complex with porcine trypsin (2010) (0)
Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a Peptidomimetic Inhibitor (2003) (0)

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What Schools Are Affiliated With R. Obert Huber?

R. Obert Huber is affiliated with the following schools:

Kyushu University
Newcastle University
University of Tokyo
University of Regensburg
Cardiff University
RWTH Aachen University
University of Bayreuth
Technical University of Munich
University of Connecticut
University of Karachi
Leiden University
University of Duisburg-Essen
Heidelberg University

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