Robert I. Haddad
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Philosophy Biology
Robert I. Haddad's Degrees
- Doctorate Medicine Harvard University
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(Suggest an Edit or Addition)Robert I. Haddad's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Comprehensive genomic characterization of head and neck squamous cell carcinomas (2015) (2860)
- Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck. (2016) (1900)
- Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. (2007) (1535)
- Recent advances in head and neck cancer. (2008) (880)
- Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort (2016) (651)
- Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trial. (2013) (567)
- Nivolumab vs investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck: 2-year long-term survival update of CheckMate 141 with analyses by tumor PD-L1 expression. (2018) (477)
- Pembrolizumab for Platinum- and Cetuximab-Refractory Head and Neck Cancer: Results From a Single-Arm, Phase II Study. (2017) (457)
- Head and Neck Cancers, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology. (2020) (454)
- Survival and human papillomavirus in oropharynx cancer in TAX 324: a subset analysis from an international phase III trial. (2011) (437)
- NCCN Guidelines Insights: Head and Neck Cancers, Version 1.2018. (2018) (381)
- Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial. (2011) (352)
- Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors (2018) (342)
- Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial. (2015) (335)
- Racial Survival Disparity in Head and Neck Cancer Results from Low Prevalence of Human Papillomavirus Infection in Black Oropharyngeal Cancer Patients (2009) (297)
- Characterization of HPV and host genome interactions in primary head and neck cancers (2014) (296)
- NCCN Guidelines Insights: Head and Neck Cancers, Version 2.2017. (2017) (285)
- Efficacy and safety of pembrolizumab in recurrent/metastatic head and neck squamous cell carcinoma: pooled analyses after long-term follow-up in KEYNOTE-012 (2018) (277)
- Nivolumab versus standard, single-agent therapy of investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141): health-related quality-of-life results from a randomised, phase 3 trial. (2017) (276)
- Response and acquired resistance to everolimus in anaplastic thyroid cancer. (2014) (264)
- Vandetanib (100 mg) in patients with locally advanced or metastatic hereditary medullary thyroid cancer. (2010) (243)
- Dose to larynx predicts for swallowing complications after intensity-modulated radiotherapy. (2008) (224)
- Genomic Analysis of Metastatic Cutaneous Squamous Cell Carcinoma (2015) (221)
- Herceptin in patients with advanced or metastatic salivary gland carcinomas. A phase II study. (2003) (216)
- A phase II study of gefitinib in patients with advanced thyroid cancer. (2007) (210)
- NCCN Guidelines Insights: Thyroid Carcinoma, Version 2.2018. (2018) (200)
- Radiation treatment breaks and ulcerative mucositis in head and neck cancer. (2008) (191)
- Head and Neck Cancers, Version 1.2015. (2015) (186)
- HER2 Expression in Salivary Gland Carcinomas (2004) (183)
- Head and neck cancers: Clinical practice guidelines in oncology (2011) (178)
- Thyroid carcinoma, version 2.2014. (2014) (176)
- Frameshift events predict anti-PD-1/L1 response in head and neck cancer. (2018) (173)
- Durvalumab with or without tremelimumab in patients with recurrent or metastatic head and neck squamous cell carcinoma: EAGLE, a randomized, open-label phase III study. (2020) (172)
- NCCN Guidelines® Insights: Head and Neck Cancers, Version 1.2022. (2022) (165)
- Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. (2013) (161)
- Trastuzumab for the treatment of salivary duct carcinoma. (2013) (150)
- Oral human papillomavirus (HPV) infection in HPV-positive patients with oropharyngeal cancer and their partners. (2014) (148)
- Head and neck cancers, version 2.2013. Featured updates to the NCCN guidelines. (2013) (147)
- Head and Neck Cancers, Version 2.2014 (2014) (145)
- Biomarkers of HPV in head and neck squamous cell carcinoma. (2012) (138)
- Small-cell carcinoma of the lung: derivation of a prognostic staging system. (1991) (138)
- Sequential therapy for the locally advanced larynx and hypopharynx cancer subgroup in TAX 324: survival, surgery, and organ preservation. (2009) (138)
- Avelumab plus standard-of-care chemoradiotherapy versus chemoradiotherapy alone in patients with locally advanced squamous cell carcinoma of the head and neck: a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial. (2021) (136)
- Head and Neck Cancers, Version 2.2013 (2013) (132)
- Neoadjuvant Nivolumab or Nivolumab Plus Ipilimumab in Untreated Oral Cavity Squamous Cell Carcinoma: A Phase 2 Open-Label Randomized Clinical Trial. (2020) (130)
- Intensive treatment and survival outcomes in NUT midline carcinoma of the head and neck (2016) (128)
- Marital status and head and neck cancer outcomes (2015) (122)
- Head and neck cancers, Version 2.2014. Clinical practice guidelines in oncology. (2014) (114)
- Antitumor activity and safety of pembrolizumab in patients (pts) with advanced squamous cell carcinoma of the head and neck (SCCHN): Preliminary results from KEYNOTE-012 expansion cohort. (2015) (112)
- Phase I study of gefitinib plus celecoxib in recurrent or metastatic squamous cell carcinoma of the head and neck. (2005) (107)
- Salivary gland tumors treated with adjuvant intensity-modulated radiotherapy with or without concurrent chemotherapy. (2012) (106)
- The role of oral hygiene in head and neck cancer: results from International Head and Neck Cancer Epidemiology (INHANCE) consortium. (2016) (100)
- Oral epithelial dysplasia and squamous cell carcinoma following allogeneic hematopoietic stem cell transplantation: clinical presentation and treatment outcomes (2011) (100)
- Docetaxel, cisplatin, and 5‐fluorouracil‐based induction chemotherapy in patients with locally advanced squamous cell carcinoma of the head and neck (2003) (100)
- Incidence and Demographic Burden of HPV-Associated Oropharyngeal Head and Neck Cancers in the United States (2019) (98)
- Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma: CSCO and ASCO Guideline. (2021) (96)
- Nivolumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: Efficacy and Safety in CheckMate 141 by Prior Cetuximab Use (2019) (95)
- Positron emission tomography with 18F‐fluorodeoxyglucose to predict pathologic response after induction chemotherapy and definitive chemoradiotherapy in head and neck cancer (2004) (95)
- Gene expression changes in peripheral blood cells provide insight into the biological mechanisms associated with regimen-related toxicities in patients being treated for head and neck cancers. (2007) (94)
- Phase 1b, multicenter, single blinded, placebo‐controlled, sequential dose escalation study to assess the safety and tolerability of topically applied AG013 in subjects with locally advanced head and neck cancer receiving induction chemotherapy (2013) (93)
- Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial (2020) (91)
- Dysphagia after Sequential Chemoradiation Therapy for Advanced Head and Neck Cancer (2006) (86)
- Anaplastic Thyroid Carcinoma, Version 2.2015. (2015) (85)
- Prognostic Implication of Persistent Human Papillomavirus Type 16 DNA Detection in Oral Rinses for Human Papillomavirus-Related Oropharyngeal Carcinoma. (2015) (83)
- Randomized phase 2 study of concomitant chemoradiotherapy using weekly carboplatin/paclitaxel with or without daily subcutaneous amifostine in patients with locally advanced head and neck cancer (2009) (82)
- Induction chemotherapy in locally advanced squamous cell carcinoma of the head and neck: role, controversy, and future directions (2018) (81)
- Clinical practice guidance for radiotherapy planning after induction chemotherapy in locoregionally advanced head-and-neck cancer. (2009) (81)
- Efficacy and toxicity of reirradiation using intensity‐modulated radiotherapy for recurrent or second primary head and neck cancer (2010) (79)
- Importance of clinical staging in limited small-cell lung cancer: a valuable system to separate prognostic subgroups. The University of Toronto Lung Oncology Group. (1993) (79)
- Incidence and timing of common adverse events in Lenvatinib-treated patients from the SELECT trial and their association with survival outcomes (2017) (78)
- Examining the need for neck dissection in the era of chemoradiation therapy for advanced head and neck cancer. (2006) (78)
- Targeted therapies for squamous cell carcinoma of the head and neck: current knowledge and future directions. (2014) (78)
- Induction chemotherapy in locally advanced squamous cell cancer of the head and neck: evolution of the sequential treatment approach. (2004) (75)
- Overcoming resistance to EGFR inhibitor in head and neck cancer: a review of the literature. (2012) (74)
- Plasma HPV cell-free DNA monitoring in advanced HPV-associated oropharyngeal cancer (2018) (74)
- Second primary malignancies following diagnosis of small-cell lung cancer. (1992) (72)
- Phase II trial of the histone deacetylase inhibitor romidepsin in patients with recurrent/metastatic head and neck cancer. (2012) (70)
- An Anatomical Site and Genetic-Based Prognostic Model for Patients With Nuclear Protein in Testis (NUT) Midline Carcinoma: Analysis of 124 Patients (2019) (69)
- Immune Profiling of Adenoid Cystic Carcinoma: PD-L2 Expression and Associations with Tumor-Infiltrating Lymphocytes (2016) (68)
- Effect of Adding Motolimod to Standard Combination Chemotherapy and Cetuximab Treatment of Patients With Squamous Cell Carcinoma of the Head and Neck: The Active8 Randomized Clinical Trial (2018) (68)
- Genomic Correlates of Response to Everolimus in Aggressive Radioiodine-refractory Thyroid Cancer: A Phase II Study (2018) (68)
- Vandetanib for the Treatment of Medullary Thyroid Cancer (2012) (68)
- Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer (2011) (66)
- beta-Tubulin-II expression strongly predicts outcome in patients receiving induction chemotherapy for locally advanced squamous carcinoma of the head and neck: a companion analysis of the TAX 324 trial. (2009) (64)
- Biomarkers predict enhanced clinical outcomes with afatinib versus methotrexate in patients with second-line recurrent and/or metastatic head and neck cancer (2017) (64)
- CheckMate 141: 1-Year Update and Subgroup Analysis of Nivolumab as First-Line Therapy in Patients with Recurrent/Metastatic Head and Neck Cancer. (2018) (63)
- Head and neck cancer (2021) (63)
- Treatment of oral cavity squamous cell carcinoma with adjuvant or definitive intensity-modulated radiation therapy. (2011) (62)
- Definitive chemoradiation alters the immunologic landscape and immune checkpoints in head and neck cancer (2016) (62)
- Endoscopic Management of Hypopharyngeal Stenosis after Organ Sparing Therapy for Head and Neck Cancer (2004) (62)
- Chemoradiotherapy for Adenoid Cystic Carcinoma: Preliminary Results of an Organ Sparing Approach (2006) (59)
- Docetaxel, cisplatin, 5-fluorouracil (TPF)-based induction chemotherapy for head and neck cancer and the case for sequential, combined-modality treatment. (2003) (57)
- Nivolumab treatment beyond RECIST‐defined progression in recurrent or metastatic squamous cell carcinoma of the head and neck in CheckMate 141: A subgroup analysis of a randomized phase 3 clinical trial (2019) (56)
- Phase I study of C-TPF in patients with locally advanced squamous cell carcinoma of the head and neck. (2009) (56)
- Serum concentrations of interleukin-8, vascular endothelial growth factor, and epidermal growth factor receptor in patients with squamous cell cancer of the head and neck. (2005) (56)
- Patient‐reported receipt of and interest in smoking‐cessation interventions after a diagnosis of cancer (2011) (55)
- Phase I dose-finding study of paclitaxel with panitumumab, carboplatin and intensity-modulated radiotherapy in patients with locally advanced squamous cell cancer of the head and neck. (2010) (54)
- A randomized phase II study of docetaxel with or without vandetanib in recurrent or metastatic squamous cell carcinoma of head and neck (SCCHN). (2013) (53)
- Tipifarnib in Head and Neck Squamous Cell Carcinoma With HRAS Mutations (2021) (53)
- Further evaluations of nivolumab (nivo) versus investigator’s choice (IC) chemotherapy for recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): CheckMate 141. (2016) (52)
- Predictors of response and survival after concurrent chemotherapy and radiation for locally advanced squamous cell carcinomas of the head and neck (2001) (51)
- Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors (2018) (51)
- Efficacy and safety of pembrolizumab in recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC): Pooled analyses after long-term follow-up in KEYNOTE-012. (2016) (50)
- Erythropoietin to treat anaemia in patients with head and neck cancer (2004) (48)
- Management of elderly patients with locoregionally confined head and neck cancer. (2017) (48)
- Relationship between radiation treatment time and overall survival after induction chemotherapy for locally advanced head-and-neck carcinoma: a subset analysis of TAX 324. (2011) (47)
- Organ Preservation and Treatment Toxicity With Induction Chemotherapy Followed by Radiation Therapy or Chemoradiation for Advanced Laryngeal Cancer (2005) (47)
- Efficacy and toxicity of chemoradiotherapy using intensity-modulated radiotherapy for unknown primary of head and neck. (2011) (47)
- Incorporation of Next-Generation Sequencing into Routine Clinical Care to Direct Treatment of Head and Neck Squamous Cell Carcinoma (2016) (47)
- Genomic determinants of response to pembrolizumab in head and neck squamous cell carcinoma (HNSCC). (2017) (45)
- Defining an inflamed tumor immunophenotype in recurrent, metastatic squamous cell carcinoma of the head and neck. (2017) (44)
- 910O Primary results of the phase III JAVELIN head & neck 100 trial: Avelumab plus chemoradiotherapy (CRT) followed by avelumab maintenance vs CRT in patients with locally advanced squamous cell carcinoma of the head and neck (LA SCCHN) (2020) (42)
- A Phase II Clinical and Pharmacodynamic Study of E7070 in Patients with Metastatic, Recurrent, or Refractory Squamous Cell Carcinoma of the Head and Neck (2004) (42)
- The PARADIGM trial: A phase III study comparing sequential therapy (ST) to concurrent chemoradiotherapy (CRT) in locally advanced head and neck cancer (LANHC). (2012) (42)
- Factors associated with smoking abstinence among smokers and recent-quitters with lung and head and neck cancer. (2012) (42)
- Open-label, long-term safety study of cevimeline in the treatment of postirradiation xerostomia. (2007) (41)
- Best Practice in Systemic Therapy for Head and Neck Squamous Cell Carcinoma (2019) (41)
- Abstract CT099: Nivolumab (nivo) vs investigator's choice (IC) for recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC): CheckMate-141 (2016) (41)
- Management of treatment-related toxicities in advanced medullary thyroid cancer. (2018) (40)
- Cancer Care Disparities during the COVID-19 Pandemic: COVID-19 and Cancer Outcomes Study (2020) (39)
- HPV16 transmission between a couple with HPV-related head and neck cancer. (2008) (39)
- Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors (2020) (38)
- Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy (2022) (38)
- Afatinib versus methotrexate in older patients with second-line recurrent and/or metastatic head and neck squamous cell carcinoma: subgroup analysis of the LUX-Head & Neck 1 trial† (2016) (38)
- Polymerase chain reaction detection of HPV in squamous carcinoma of the oropharynx. (2010) (38)
- Abstract LB-339: Biomarkers predictive of response to pembrolizumab in head and neck cancer (HNSCC) (2018) (37)
- Thyroid carcinoma. (2010) (36)
- A phase II open-label study of vandetanib in patients with locally advanced or metastatic hereditary medullary thyroid cancer (2008) (35)
- Multidisciplinary approach to cancer treatment: focus on head and neck cancer. (2008) (35)
- Combined antegrade and retrograde esophageal dilation for head and neck cancer‐related complete esophageal stenosis (2010) (35)
- Comparative Analysis of MicroRNA Expression among Benign and Malignant Tongue Tissue and Plasma of Patients with Tongue Cancer (2017) (33)
- Acupuncture for Dysphagia After Chemoradiation Therapy in Head and Neck Cancer: A Case Series Report (2010) (33)
- Mouthwash use and cancer of the head and neck: a pooled analysis from the International Head and Neck Cancer Epidemiology Consortium (2016) (33)
- Biologic predictors of serologic responses to HPV in oropharyngeal cancer: The HOTSPOT study. (2015) (33)
- 1043OTreatment beyond progression with nivolumab in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) in the phase 3 checkmate 141 study: A biomarker analysis and updated clinical outcomes (2017) (32)
- Chemoradiation‐Induced Cell Loss in Human Submandibular Glands (2005) (32)
- EAGLE: A phase 3, randomized, open-label study of durvalumab (D) with or without tremelimumab (T) in patients (pts) with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC). (2019) (31)
- Concurrent weekly docetaxel and concomitant boost radiation therapy in the treatment of locally advanced squamous cell cancer of the head and neck. (2006) (31)
- Biomarkers and response to pembrolizumab (pembro) in recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC). (2016) (31)
- Medullary carcinoma: Clinical practice guidelines in oncology™ (2010) (31)
- The Use of Hyperbaric Oxygen for the Prevention and Management of Osteoradionecrosis of the Jaw: A Dana‐Farber/Brigham and Women's Cancer Center Multidisciplinary Guideline (2017) (31)
- The Use of Hyperbaric Oxygen for the Prevention and Management of Osteoradionecrosis of the Jaw: A Dana-Farber/Brigham and Women's Cancer Center Multidisciplinary Guideline. (2017) (30)
- Phase II study of induction chemotherapy with paclitaxel, ifosfamide, and carboplatin (TIC) for patients with locally advanced squamous cell carcinoma of the head and neck (2003) (29)
- Salivary HPV DNA informs locoregional disease status in advanced HPV-associated oropharyngeal cancer. (2019) (28)
- Novel biomarker panel predicts prognosis in human papillomavirus‐negative oropharyngeal cancer (2012) (28)
- Induction chemotherapy for locoregionally advanced head and neck cancer: past, present, future? (2013) (28)
- Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck (2021) (27)
- Medullary carcinoma. (2010) (27)
- Efficacy and Safety of Vandetanib in Progressive and Symptomatic Medullary Thyroid Cancer: Post Hoc Analysis From the ZETA Trial (2020) (26)
- Nivolumab (Nivo) vs investigator’s choice (IC) in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): Efficacy and safety in CheckMate 141 by prior cetuximab use. (2017) (26)
- Human papillomavirus (HPV) 16 antibodies at diagnosis of HPV-related oropharyngeal cancer and antibody trajectories after treatment. (2017) (26)
- Oral Immune-Related Adverse Events Associated with PD-1 Inhibitor Therapy: A Case Series. (2020) (26)
- Cabozantinib in Patients with Advanced Merkel Cell Carcinoma. (2018) (25)
- Barriers to clinical trial recruitment in head and neck cancer. (2015) (25)
- Evaluating the Utility and Prevalence of HPV Biomarkers in Oral Rinses and Serology for HPV-related Oropharyngeal Cancer (2019) (25)
- CDKN2A Alterations and Response to Immunotherapy in Solid Tumors (2021) (24)
- The effects of somatostatin and octreotide on experimental and human acute pancreatitis. (2000) (24)
- Success of endoscopic pharyngoesophageal dilation after head and neck cancer treatment (2013) (24)
- A Pilot Surrogate Endpoint Biomarker Study of Celecoxib in Oral Premalignant Lesions (2008) (24)
- Rate of pathologic complete responses to docetaxel, cisplatin, and fluorouracil induction chemotherapy in patients with squamous cell carcinoma of the head and neck. (2006) (24)
- Afatinib vs Placebo as Adjuvant Therapy After Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck: A Randomized Clinical Trial. (2019) (24)
- Acupuncture for dysphagia after chemoradiation in head and neck cancer: rationale and design of a randomized, sham-controlled trial. (2012) (24)
- Swallowing Function following Postchemoradiotherapy Neck Dissection (2011) (23)
- Induction chemotherapy in locally advanced head and neck cancer: a new standard of care? (2008) (23)
- Plasma-based tumor mutational burden (bTMB) as predictor for survival in phase III EAGLE study: Durvalumab (D) ± tremelimumab (T) versus chemotherapy (CT) in recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) after platinum failure. (2020) (23)
- The Benefits of Adjuvant Trastuzumab for HER-2-Positive Salivary Gland Cancers. (2020) (22)
- A randomized, open-label, phase 3 study of nivolumab in combination with ipilimumab vs extreme regimen (cetuximab + cisplatin/carboplatin + fluorouracil) as first-line therapy in patients with recurrent or metastatic squamous cell carcinoma of the head and neck-CheckMate 651 (2016) (22)
- Preliminary results from KEYNOTE-055: Pembrolizumab after platinum and cetuximab failure in head and neck squamous cell carcinoma (HNSCC). (2016) (22)
- A phase II study of nivolumab (N) plus ipilimumab (I) in radioidine refractory differentiated thyroid cancer (RAIR DTC) with exploratory cohorts in anaplastic (ATC) and medullary thyroid cancer (MTC). (2020) (21)
- Photodynamic therapy of cancer of the esophagus using systemic aminolevulinic acid and a non laser light source: a phase I/II study. (1999) (21)
- Photodynamic therapy of murine colon cancer and melanoma using systemic aminolevulinic acid as a photosensitizer. (2000) (21)
- Behavior of oral squamous cell carcinoma in subjects with prior lichen planus (2007) (21)
- Everolimus in Anaplastic Thyroid Cancer: A Case Series (2019) (21)
- A phase II study of everolimus in patients with aggressive RAI refractory (RAIR) thyroid cancer (TC). (2013) (20)
- Nivolumab (Nivo) vs investigator’s choice (IC) for platinum-refractory (PR) recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN; Checkmate 141): Outcomes in first-line (1L) R/m patients and updated safety and efficacy. (2017) (20)
- Long-term outcomes and clinicogenomic correlates in recurrent, metastatic adenoid cystic carcinoma. (2020) (20)
- Rationale and design of LUX-Head & Neck 1: a randomised, Phase III trial of afatinib versus methotrexate in patients with recurrent and/or metastatic head and neck squamous cell carcinoma who progressed after platinum-based therapy (2014) (20)
- Phase III, randomized, open-label study of durvalumab (MEDI4736) monotherapy, or durvalumab + tremelimumab, versus standard of care (SoC), in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): eagle (2015) (20)
- Mucosal melanoma of the head and neck. (2012) (19)
- Influence of tumor mutational burden, inflammatory gene expression profile, and PD-L1 expression on response to pembrolizumab in head and neck squamous cell carcinoma (2022) (19)
- JAVELIN head and neck 100: A phase 3 trial of avelumab in combination with chemoradiotherapy (CRT) vs CRT for 1st-line treatment of locally advanced squamous cell carcinoma of the head and neck (LA SCCHN). (2017) (19)
- Abstract CT022: Evaluation of oral microbiome profiling as a response biomarker in squamous cell carcinoma of the head and neck: Analyses from CheckMate 141 (2017) (19)
- Evaluating the PD-1 Axis and Immune Effector Cell Infiltration in Oropharyngeal Squamous Cell Carcinoma. (2018) (19)
- Acupuncture for Chemoradiation Therapy-Related Dysphagia in Head and Neck Cancer: A Pilot Randomized Sham-Controlled Trial. (2016) (18)
- Integration of chemotherapy in the curative treatment of locally advanced head and neck cancer (2003) (18)
- Salivary and serum HPV antibody levels before and after definitive treatment in patients with oropharyngeal squamous cell carcinoma. (2017) (18)
- Head and neck cancers. (2011) (18)
- Phase II randomized study of concomitant chemoradiation using weekly carboplatin/paclitaxel with or without daily subcutaneous amifostine in patients with newly diagnosed locally advanced squamous cell carcinoma of the head and neck. (2003) (18)
- Preoperative pulmonary function tests do not predict outcome after coronary artery bypass. (1997) (18)
- Novel agents for the treatment of mucositis. (2007) (18)
- Improved outcomes in PI3K-pathway-altered metastatic HPV oropharyngeal cancer. (2018) (17)
- Oropharynx cancer (OPC) in TAX 324: Human papillomavirus (HPV) and survival. (2010) (17)
- Abstract CT021: Tumor-associated immune cell PD-L1 expression and peripheral immune profiling: Analyses from CheckMate 141 (2017) (17)
- Phase I study of panitumumab + chemoradiotherapy (CRT) for head and neck cancer (HNC) (2008) (16)
- Treatment of oropharyngeal squamous cell carcinoma with IMRT: patterns of failure after concurrent chemoradiotherapy and sequential therapy. (2012) (16)
- Phase I study of panitumumab, chemotherapy and intensity-modulated radiotherapy (IMRT) for head and neck cancer (HNC): Early results (2007) (16)
- Organ preservation for adenoid cystic carcinoma of the larynx. (2013) (16)
- Benefits of radioimmunoguided surgery for pelvic recurrence. (2001) (16)
- Human papillomavirus-associated adenocarcinoma of the base of the tongue. (2013) (16)
- Human Papillomavirus-Associated Oropharynx Cancer (HPV-OPC): Treatment Options (2014) (16)
- Biomarker analysis in recurrent and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC) patients (pts) treated with second-line afatinib versus methotrexate (MTX): LUX-Head & Neck 1 (LUX-H&N1). (2015) (15)
- Weekly paclitaxel, carboplatin, cetuximab, and cetuximab, docetaxel, cisplatin, and fluorouracil, followed by local therapy in previously untreated, locally advanced head and neck squamous cell carcinoma (2019) (15)
- Palliative chemotherapy in patients with salivary gland neoplasms and preliminary reports of 2 recent phase II studies with trastuzumab and gemcitabine. (2003) (15)
- Randomized phase II trial of cixutumumab alone or with cetuximab for refractory recurrent/metastatic head and neck squamous cell carcinoma. (2018) (15)
- Utilizing computed tomography as a road map for designing selective and superselective neck dissection after chemoradiotherapy (2010) (15)
- Seeking alternative biological therapies: the future of targeted molecular treatment. (2009) (15)
- Enhanced pathologic tumor response with two cycles of neoadjuvant pembrolizumab in surgically resectable, locally advanced HPV-negative head and neck squamous cell carcinoma (HNSCC). (2021) (15)
- Effects of definitive chemoradiation on circulating immunologic angiogenic cytokines in head and neck cancer patients (2016) (15)
- Chromosome 3q arm gain linked to immunotherapy response in advanced cutaneous squamous cell carcinoma. (2019) (14)
- A phase II trial of all-trans retinoic acid (ATRA) in advanced adenoid cystic carcinoma. (2021) (14)
- Thyroid Carcinoma Clinical Practice Guidelines in Oncology (2010) (14)
- Cetuximab added to docetaxel, cisplatin, 5-fluorouracil Induction chemotherapy (C-TPF) in patients with newly diagnosed locally advanced head and neck cancer: A phase I study (2008) (14)
- Thyroid Carcinoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology. (2022) (14)
- Patterns of failure after reirradiation with intensity-modulated radiation therapy and the competing risk of out-of-field recurrences. (2016) (14)
- Long term survival with adjuvant carboplatin, paclitaxel, and radiation therapy in anaplastic thyroid cancer. (2005) (14)
- Cost-effectiveness analysis of nivolumab for the treatment of squamous cell carcinoma of the head and neck in the United States (2020) (14)
- KEYNOTE-689: Phase 3 study of adjuvant and neoadjuvant pembrolizumab combined with standard of care (SOC) in patients with resectable, locally advanced head and neck squamous cell carcinoma. (2019) (14)
- How to incorporate new tyrosine kinase inhibitors in the treatment of patients with medullary thyroid cancer. (2013) (13)
- Aggressive treatment and survival outcomes in NUT midline carcinoma (NMC) of the head and neck (HN). (2014) (13)
- IMvoke010: Randomized phase III study of atezolizumab (atezo) as adjuvant monotherapy after definitive therapy of squamous cell carcinoma of the head and neck (SCCHN). (2018) (13)
- Inhibitor-Sensitive FGFR 2 and FGFR 3 Mutations in Lung Squamous Cell Carcinoma (2013) (12)
- LUX-head and neck 2: Randomized, double-blind, placebo-controlled, phase III trial of afatinib as adjuvant therapy after chemoradiation (CRT) in primary unresected, high/intermediate-risk, squamous cell cancer of the head and neck (HNSCC) patients (pts). (2017) (12)
- Continuous Intravenous Octreotide Treatment for Acute Experimental Pancreatitis (1999) (12)
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- LBA29_PRAFATINIB VERSUS METHOTREXATE (MTX) AS SECOND-LINE TREATMENT FOR PATIENTS WITH RECURRENT AND/OR METASTATIC (R/M) HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC) WHO PROGRESSED AFTER PLATINUM-BASED THERAPY: PRIMARY EFFICACY RESULTS OF LUX-HEAD & NECK 1, A PHASE III TRIAL (2014) (11)
- Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus-Unrelated Head and Neck Cancer: A Multicenter, Phase 2 Trial (2020) (11)
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- Dose to the Larynx Predicts for Swallowing Complications Following IMRT and Chemotherapy (2007) (10)
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- Ensuring head and neck oncology patients receive recommended pretreatment dental evaluations. (2015) (10)
- Larynx preservation: a debate worth preserving. (2013) (10)
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- POSITRON EMISSION TOMOGRAPHY WITH 18 F-FLUORODEOXYGLUCOSE TO PREDICT PATHOLOGIC RESPONSE AFTER INDUCTION CHEMOTHERAPY AND DEFINITIVE CHEMORADIOTHERAPY IN HEAD AND NECK CANCER (2004) (10)
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- Phase II study of CC-486 (oral azacitidine) in previously treated patients with locally advanced or metastatic nasopharyngeal carcinoma. (2019) (9)
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- New developments in thyroid cancer. (2013) (9)
- Double-blind, two-arm, phase 2 study of nivolumab (nivo) in combination with ipilimumab (ipi) versus nivo and ipi-placebo (PBO) as first-line (1L) therapy in patients (pts) with recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN)—CheckMate 714 (2016) (9)
- Two-year Update From CheckMate 141: Outcomes With Nivolumab (Nivo) vs Investigator's Choice (IC) in Recurrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN) in the Overall Population and PD-L1 Subgroups (2018) (9)
- Phase I study of gefitinib plus celecoxib in patients with metastatic and/or locally recurrent squamous cell carcinoma of the head and neck (SCCHN) (2004) (9)
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- Care disruptions among patients with lung cancer: A COVID-19 and cancer outcomes study (2021) (8)
- Metastatic human papillomavirus-positive nasopharyngeal carcinoma with an unusual pattern of aggressive hematogenous spread. (2012) (8)
- Optimizing Tobacco Cessation Resource Awareness Among Patients and Providers. (2016) (8)
- Oral HPV infection in HPV-positive oropharyngeal cancer cases and their spouses. (2013) (8)
- IMRT‐based treatment of unknown primary malignancy of the head and neck: Outcomes and improved toxicity with decreased mucosal dose and larynx sparing (2019) (8)
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- KEYNOTE-055: A phase II trial of single agent pembrolizumab in patients (pts) with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) who have failed platinum and cetuximab. (2015) (8)
- Oncology clinical trial disruption during the COVID-19 pandemic: a COVID-19 and cancer outcomes study (2022) (8)
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- Long-term results from TAX324: A phase III trial of sequential therapy comparing TPF to PF in locally advanced (LA) squamous cell cancer of the head and neck (HNC). (2010) (7)
- A Phase 1 Study of Afatinib in Combination with Postoperative Radiation Therapy with and Without Weekly Docetaxel in Intermediate- and High-Risk Patients with Resected Squamous Cell Carcinoma of the Head and Neck. (2019) (7)
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- Comprehensive Immunoprofiling of High-Risk Oral Proliferative and Localized Leukoplakia (2021) (6)
- Weekly paclitaxel, carboplatin, cetuximab (PCC), and cetuximab, docetaxel, cisplatin, and fluorouracil (C-TPF), followed by risk-based local therapy in previously untreated, locally advanced head and neck squamous cell carcinoma (LAHNSCC). (2015) (6)
- 2866 Antitumor activity of the Anti-PD-1 antibody pembrolizumab in subgroups of patients with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC): Exploratory analyses from KEYNOTE-012 (2015) (5)
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- Nivolumab Plus Ipilimumab Versus EXTREME Regimen as First-Line Treatment for Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck: The Final Results of CheckMate 651 (2022) (5)
- Integrating novel agents into the curative treatment of head and neck cancer (2006) (5)
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- Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–unrelated Head and Neck Cancer: A Multicenter, Phase II Trial (2021) (2)
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- Tumor Biomarker Association With Clinical Outcomes in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) Patients (Pts) Treated With Afatinib Versus Methotrexate (MTX): LUX-Head & Neck 1 (LHN1) (2016) (2)
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- Local Control following Combination Hypofractionated Radiotherapy and Pembrolizumab in A Phase II Trial of Recurrent or Metastatic Adenoid Cystic Carcinoma Patients (2019) (0)
- Head and Neck CancersPractice Guidelines in Oncology (2011) (0)
- PIK-ing out an intermediate-risk subgroup in advanced adenoid cystic carcinoma (2020) (0)
- 2378 : Use Of Peripheral Blood Monocytes (PBM) To Define Changes in Gene Expression Associated With Amifostine Treatment and Their Association With Oral Mucositis (OM) in Patients Being Treated With Chemoradiotherapy for Squamous Cell Carcinoma of the Head and Neck(SCCHN) (2006) (0)
- Abstract S06-02: Disruption to care of patients with thoracic malignancies: A COVID-19 and cancer outcomes study (2021) (0)
- Immunotherapy and head and neck cancer: Focus on recurrent and metastatic disease (2018) (0)
- Abstract 902: Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer (2011) (0)
- Recurrent or metastatic head and neck squamous cell carcinoma that is not responsive to platinum-based chemotherapy progresses very rapidly , and patients have a very poor prognosis , ” (2016) (0)
- Long-term symptom burden and orodental health of oropharyngeal cancer (OPC) survivors following treatment with chemoradiotherapy (CRT) or sequential therapy (ST). (2013) (0)
- A Phase 2/3, Randomized, Open-Label Study of Bempegaldesleukin Plus Pembrolizumab vs. Pembrolizumab Alone in First-Line Treatment of Patients with Metastatic or Recurrent Head and Neck Squamous Cell Carcinoma with PD-L1-Expressing Tumors (PROPEL-36) (2022) (0)
- Experimental Design: We performed targeted sequencing of 504 cancer-associated genes on lymph node metastases in 29 patients with cSCC and identified mutations and somatic copy number alterations associated with metastatic cSCC (2015) (0)
- Patterns of Failure After Reirradiation (reRT) With Intensity Modulated Radiation Therapy (IMRT): Not Just a Local Issue (2015) (0)
- Toxicity and Survival After Reirradiation (reRT) With IMRT for Recurrent Squamous Cell Cancer of the Head and Neck (SCCHN) (2014) (0)
- Abstract 4497: Biomarkers of HPV in head and neck squamous cell carcinoma (2012) (0)
- Poster ViewingOutcomes and Patterns of Failure After Postoperative or Definitive Intensity-modulated Radiation Therapy for Oral Cavity Squamous Cell Carcinoma (2017) (0)
- PET/CT imaging in patients with suspected recurrence of pancreatic cancer. (2009) (0)
- Chemotherapy outcomes following immunotherapy failure in advanced squamous cell carcinoma of the head and neck (2020) (0)
- Abstract CT236: INTERLINK-1: A phase 3, randomized, double-blind, placebo-controlled, multicenter, global study of monalizumab in combination with cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma previously treated with an immune checkpoint inhibitor (2022) (0)
- 10:40 AM: Behavior of Oral SCCA in Subjects with Prior Lichen Planus (2006) (0)
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