Robert J Schwartz
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Engineering Computer Science
Robert J Schwartz's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
- Bachelors Computer Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Robert J Schwartz's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Dysregulation of Cardiogenesis, Cardiac Conduction, and Cell Cycle in Mice Lacking miRNA-1-2 (2007) (1457)
- The cardiac transcription factors Nkx2‐5 and GATA‐4 are mutual cofactors (1997) (699)
- Myogenic Vector Expression of Insulin-like Growth Factor I Stimulates Muscle Cell Differentiation and Myofiber Hypertrophy in Transgenic Mice (*) (1995) (668)
- MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. (2008) (629)
- Thymosin β4 induces adult epicardial progenitor mobilization and neovascularization (2007) (628)
- Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning (2005) (496)
- Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size (2011) (476)
- Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-κB activation in response to tumor necrosis factor α (1998) (446)
- Cloning and sequencing of a deoxyribonucleic acid copy of glyceraldehyde-3-phosphate dehydrogenase messenger ribonucleic acid isolated from chicken muscle. (1983) (428)
- Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability (2006) (405)
- Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract (2004) (370)
- TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice (2000) (355)
- A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf–Hirschhorn syndrome (2009) (343)
- GATA-4 and Nkx-2.5 Coactivate Nkx-2 DNA Binding Targets: Role for Regulating Early Cardiac Gene Expression (1998) (334)
- Identification of Novel DNA Binding Targets and Regulatory Domains of a Murine Tinman Homeodomain Factor, nkx-2.5(*) (1995) (315)
- Multiple roles for Sox2 in the developing and adult mouse trachea (2009) (307)
- Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation (1988) (306)
- Embryonic expression of an Nkx2‐5/Cre gene using ROSA26 reporter mice (2001) (305)
- Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription (1996) (302)
- Essential role of GATA-4 in cell survival and drug-induced cardiotoxicity. (2004) (288)
- Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis. (2003) (282)
- Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-kappaB activation in response to tumor necrosis factor alpha. (1998) (280)
- Hop Is an Unusual Homeobox Gene that Modulates Cardiac Development (2002) (276)
- Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein. (2004) (268)
- Morphogenesis of the right ventricle requires myocardial expression of Gata4. (2005) (256)
- Cysteine-rich LIM-only proteins CRP1 and CRP2 are potent smooth muscle differentiation cofactors. (2003) (238)
- Synthetic muscle promoters: activities exceeding naturally occurring regulatory sequences (1999) (231)
- Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling. (2004) (230)
- Fgf8 is required for anterior heart field development (2006) (226)
- Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2. (2000) (223)
- Rho kinases play an obligatory role in vertebrate embryonic organogenesis. (2001) (221)
- Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis (2006) (220)
- Impaired vascular contractility and blood pressure homeostasis in the smooth muscle α‐actin null mouse (2000) (211)
- Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal alpha-actin transcription in embryonic myoblasts. (1992) (209)
- Cardiac Tissue Enriched Factors Serum Response Factor and GATA-4 Are Mutual Coregulators (2000) (203)
- Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription. (1999) (203)
- Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors (2012) (199)
- SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development. (2010) (197)
- Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis (2006) (196)
- Retinoic acid deficiency alters second heart field formation (2008) (192)
- Avian serum response factor expression restricted primarily to muscle cell lineages is required for alpha-actin gene transcription. (1996) (191)
- Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus (1983) (186)
- Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function (2012) (181)
- The Cardiac Determination Factor, Nkx2-5, Is Activated by Mutual Cofactors GATA-4 and Smad1/4 via a Novel Upstream Enhancer* (2004) (176)
- Combinatorial Expression of GATA4, Nkx2-5, and Serum Response Factor Directs Early Cardiac Gene Activity* (2002) (175)
- Cardiac-Specific Ablation of G-Protein Receptor Kinase 2 Redefines Its Roles in Heart Development and &bgr;-Adrenergic Signaling (2006) (174)
- The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium (1996) (174)
- Defective erythroid differentiation in miR-451 mutant mice mediated by 14-3-3zeta. (2010) (173)
- Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries (2013) (171)
- RhoA Signaling via Serum Response Factor Plays an Obligatory Role in Myogenic Differentiation* (1998) (169)
- Transforming growth factor-beta response elements of the skeletal alpha-actin gene. Combinatorial action of serum response factor, YY1, and the SV40 enhancer-binding protein, TEF-1. (1994) (163)
- Local insulin‐like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice (1999) (162)
- A role for serum response factor in coronary smooth muscle differentiation from proepicardial cells. (1999) (160)
- Sequential expression of chicken actin genes during myogenesis (1986) (159)
- Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells (2007) (156)
- Signaling via the Tgf-beta type I receptor Alk5 in heart development. (2008) (153)
- Cardiac Muscle Plasticity in Adult and Embryo by Heart‐Derived Progenitor Cells (2004) (152)
- Organization and Myogenic Restricted Expression of the Murine Serum Response Factor Gene (1997) (151)
- Insulin-like Growth Factor-I Extends in VitroReplicative Life Span of Skeletal Muscle Satellite Cells by Enhancing G1/S Cell Cycle Progression via the Activation of Phosphatidylinositol 3′-Kinase/Akt Signaling Pathway* (2000) (146)
- Genetic Fate Mapping Identifies Second Heart Field Progenitor Cells As a Source of Adipocytes in Arrhythmogenic Right Ventricular Cardiomyopathy (2009) (145)
- Conditional Mutagenesis of the Murine Serum Response Factor Gene Blocks Cardiogenesis and the Transcription of Downstream Gene Targets* (2005) (143)
- Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development (2007) (139)
- Elements of the smooth muscle alpha-actin promoter required in cis for transcriptional activation in smooth muscle. Evidence for cell type-specific regulation. (1992) (134)
- Threshold-specific requirements for Bmp4 in mandibular development. (2005) (132)
- Identification of upstream regulatory regions in the heart-expressed homeobox gene Nkx2-5. (1999) (130)
- Activation of skeletal alpha-actin gene transcription: the cooperative formation of serum response factor-binding complexes over positive cis-acting promoter serum response elements displaces a negative-acting nuclear factor enriched in replicating myoblasts and nonmyogenic cells (1991) (130)
- Serum response factor micromanaging cardiogenesis. (2007) (128)
- The vascular smooth muscle alpha-actin gene is reactivated during cardiac hypertrophy provoked by load. (1991) (127)
- Prox1 maintains muscle structure and growth in the developing heart (2009) (126)
- Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements. (1996) (124)
- Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development. (2010) (122)
- COUP-TFII is essential for radial and anteroposterior patterning of the stomach (2005) (120)
- Targeted Expression of IGF‐1 Transgene to Skeletal Muscle Accelerates Muscle and Motor Neuron Regeneration (2003) (120)
- Bifunctional transcriptional properties of YY1 in regulating muscle actin and c-myc gene expression during myogenesis. (1994) (119)
- SRF and TEF-1 control of chicken skeletal alpha-actin gene during slow-muscle hypertrophy. (1996) (119)
- A combination of closely associated positive and negative cis-acting promoter elements regulates transcription of the skeletal alpha-actin gene (1990) (117)
- Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation. (2002) (112)
- Myogenic expression of an injectable protease-resistant growth hormone–releasing hormone augments long-term growth in pigs (1999) (111)
- Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis (2011) (110)
- Transcriptional regulation of a mouse Clara cell-specific protein (mCC10) gene by the NKx transcription factor family members thyroid transciption factor 1 and cardiac muscle-specific homeobox protein (CSX) (1996) (109)
- SUMO-1 Modification Activated GATA4-dependent Cardiogenic Gene Activity* (2004) (107)
- Delimitation and characterization of cis-acting DNA sequences required for the regulated expression and transcriptional control of the chicken skeletal alpha-actin gene (1986) (106)
- Serum Response Factor Mediates AP-1-dependent Induction of the Skeletal -Actin Promoter in Ventricular Myocytes (*) (1996) (106)
- Insulin-like growth factor-I extends in vitro replicative life span of skeletal muscle satellite cells by enhancing G1/S cell cycle progression via the activation of phosphatidylinositol 3'-kinase/Akt signaling pathway. (2000) (106)
- Dominant Negative Murine Serum Response Factor: Alternative Splicing within the Activation Domain Inhibits Transactivation of Serum Response Factor Binding Targets (1999) (105)
- Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart (2008) (103)
- Regulation of muscle differentiation: cloning of sequences from alpha-actin messenger ribonucleic acid. (1980) (101)
- Differential regulation of skeletal alpha-actin transcription in cardiac muscle by two fibroblast growth factors. (1990) (98)
- The developmentally regulated expression of serum response factor plays a key role in the control of smooth muscle-specific genes. (1998) (96)
- Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation. (2008) (94)
- Complete sequence of the chicken glyceraldehyde-3-phosphate dehydrogenase gene. (1985) (94)
- TNF‐α regulates early differentiation of C2C12 myoblasts in an autocrine fashion (2001) (94)
- The Smooth Muscle γ-Actin Gene Promoter Is a Molecular Target for the Mouse bagpipe Homologue, mNkx3-1, and Serum Response Factor* (2000) (94)
- Msx2 and Necdin Combined Activities Are Required for Smooth Muscle Differentiation in Mesoangioblast Stem Cells (2004) (92)
- Transforming Growth Factor-β Induction of Smooth Muscle Cell Phenotpye Requires Transcriptional and Post-transcriptional Control of Serum Response Factor* (2002) (92)
- Overexpression of IGF-I in skeletal muscle of transgenic mice does not prevent unloading-induced atrophy. (1998) (91)
- Identification of Direct Serum-response Factor Gene Targets during Me2SO-induced P19 Cardiac Cell Differentiation* (2005) (90)
- Gene switching in myogenesis: differential expression of the chicken actin multigene family. (1981) (87)
- Calcium/Calmodulin-dependent Protein Kinase Activates Serum Response Factor Transcription Activity by Its Dissociation from Histone Deacetylase, HDAC4 (2003) (87)
- Myocardin Sumoylation Transactivates Cardiogenic Genes in Pluripotent 10T1/2 Fibroblasts (2006) (85)
- T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfβ2 expression and endocardial cushion formation (2009) (85)
- Evidence for a role of Smad6 in chick cardiac development. (1999) (84)
- Inhibitory Cardiac Transcription Factor, SRF-N, Is Generated by Caspase 3 Cleavage in Human Heart Failure and Attenuated by Ventricular Unloading (2003) (83)
- Regulation of skeletal alpha-actin promoter in young chickens during hypertrophy caused by stretch overload. (1995) (82)
- Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity (2013) (81)
- Myoepithelial Cell Contraction and Milk Ejection Are Impaired in Mammary Glands of Mice Lacking Smooth Muscle Alpha-Actin1 (2011) (78)
- Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development. (2009) (77)
- A 29-nucleotide DNA segment containing an evolutionarily conserved motif is required in cis for cell-type-restricted repression of the chicken alpha-smooth muscle actin gene core promoter (1988) (77)
- Serum response factor MADS box serine-162 phosphorylation switches proliferation and myogenic gene programs. (2006) (75)
- Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice. (2006) (72)
- Defective sumoylation pathway directs congenital heart disease. (2011) (71)
- Sumoylation and regulation of cardiac gene expression. (2010) (70)
- Effects of estrogen on gene expression in the chick oviduct. IV. Initiation of RNA synthesis on DNA and chromatin. (1975) (70)
- Chicken Nkx-2.8: a novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm. (1997) (70)
- Physical Interaction between the MADS Box of Serum Response Factor and the TEA/ATTS DNA-binding Domain of Transcription Enhancer Factor-1* (2001) (70)
- Hemogenic endocardium contributes to transient definitive hematopoiesis (2013) (69)
- Novel chicken actin gene: third cytoplasmic isoform (1985) (69)
- Heterodimers of myogenic helix-loop-helix regulatory factors and E12 bind a complex element governing myogenic induction of the avian cardiac alpha-actin promoter (1991) (68)
- MicroRNA-17-92, a Direct Ap-2α Transcriptional Target, Modulates T-Box Factor Activity in Orofacial Clefting (2013) (68)
- miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification (2016) (67)
- Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation. (2011) (67)
- βl integrin and organized actin filaments facilitate cardiomyocyte‐specific RhoA‐dependent activation of the skeletal α‐actin promoter (2001) (67)
- Frs2α-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis (2008) (66)
- Competition between negative acting YY1 versus positive acting serum response factor and tinman homologue Nkx-2.5 regulates cardiac alpha-actin promoter activity. (1997) (65)
- Intron-dependent evolution of chicken glyceraldehyde phosphate dehydrogenase gene (1985) (64)
- Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment (2007) (63)
- Isolation and characterization of six different chicken actin genes (1984) (62)
- Regulation of gene expression in eucaryotes. (1977) (62)
- Recruitment of the Androgen Receptor via Serum Response Factor Facilitates Expression of a Myogenic Gene* (2005) (62)
- Serum Response Factor, an Enriched Cardiac Mesoderm Obligatory Factor, Is a Downstream Gene Target for Tbx Genes* (2005) (62)
- TNF-alpha regulates early differentiation of C2C12 myoblasts in an autocrine fashion. (2001) (62)
- Enhanced growth by ectopic expression of growth hormone releasing hormone using an injectable myogenic vector (1997) (60)
- Effect of estrogen on gene expression in the chick oviduct. V. Changes in the number of RNA polymerase binding and initiation sites in chromatin. (1975) (60)
- Effects of estrogen on gene expression in chick oviduct: nuclear receptor levels and initiation of transcription. (1975) (59)
- Regulation of organ development by the NKX-homeodomain factors: an NKX code. (2005) (59)
- Positive and negative control of the skeletal alpha-actin promoter in cardiac muscle. A proximal serum response element is sufficient for induction by basic fibroblast growth factor (FGF) but not for inhibition by acidic FGF. (1992) (57)
- Thymosin β‐4 Is Essential for Coronary Vessel Development and Promotes Neovascularization via Adult Epicardium (2007) (57)
- Growth and Tissue Accretion Rates of Swine Expressing an Insulin-like Growth Factor I Transgene (2004) (57)
- GATA-4 and Serum Response Factor Regulate Transcription of the Muscle-specific Carnitine Palmitoyltransferase I β in Rat Heart* (2001) (56)
- SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin (2009) (55)
- Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation (2014) (54)
- Cardiovascular abnormalities in Folr1 knockout mice and folate rescue. (2007) (54)
- Structure and complete nucleotide sequence of the chicken alpha-smooth muscle (aortic) actin gene. An actin gene which produces multiple messenger RNAs. (1986) (53)
- Persistent IGF-I overexpression in skeletal muscle transiently enhances DNA accretion and growth. (2003) (52)
- A review of regulation of gene expression by steroid hormone receptors. (1976) (52)
- Conditional Ablation of Ezh2 in Murine Hearts Reveals Its Essential Roles in Endocardial Cushion Formation, Cardiomyocyte Proliferation and Survival (2012) (52)
- Regulation of Cardiac Specific nkx2.5 Gene Activity by Small Ubiquitin-like Modifier* (2008) (51)
- Utility of firefly luciferase as a reporter gene for promoter activity in transgenic mice. (1988) (51)
- Tissue restricted and stage specific transcription is maintained within 411 nucleotides flanking the 5' end of the chicken alpha-skeletal actin gene. (1986) (50)
- Disruption of Rho signaling results in progressive atrioventricular conduction defects while ventricular function remains preserved (2004) (50)
- The avian cardiac alpha-actin promoter is regulated through a pair of complex elements composed of E boxes and serum response elements that bind both positive- and negative-acting factors. (1994) (49)
- Effect of estrogen on gene expression in the chick oviduct. In vitro transcription of the ovalbumin gene in chromatin. (1976) (49)
- SRF protein is upregulated during stretch-induced hypertrophy of rooster ALD muscle. (1999) (49)
- The complete sequence of the chicken α-cardiac actin gene: a highly conserved vertebrate gene (1985) (48)
- Whole animal knockout of smooth muscle alpha‐actin does not alter excisional wound healing or the fibroblast‐to‐myofibroblast transition (2013) (47)
- Complex cardiac Nkx2-5 gene expression activated by noggin-sensitive enhancers followed by chamber-specific modules. (2005) (47)
- Progesterone-binding components of chick oviduct. In vitro effect of receptor subunits on gene transcription. (1976) (45)
- LIM-only protein, CRP2, switched on smooth muscle gene activity in adult cardiac myocytes (2007) (44)
- The FGF-BMP Signaling Axis Regulates Outflow Tract Valve Primordium Formation by Promoting Cushion Neural Crest Cell Differentiation (2010) (43)
- A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice. (1998) (41)
- Phorbol esters selectively downregulate contractile protein gene expression in terminally differentiated myotubes through transcriptional repression and message destabilization (1991) (39)
- Cellular localization of muscle and nonmuscle actin mRNAs in chicken primary myogenic cultures: the induction of alpha-skeletal actin mRNA is regulated independently of alpha-cardiac actin gene expression (1988) (39)
- Mechanism of fibrotic cardiomyopathy in mice expressing truncated Rho‐associated coiled‐coil protein kinase 1 (2012) (38)
- Alterations in iodinated cell surface proteins during myogenesis. (1978) (38)
- Smyd1 Facilitates Heart Development by Antagonizing Oxidative and ER Stress Responses (2015) (38)
- Transient Expression of FRNK Reveals Stage-Specific Requirement for Focal Adhesion Kinase Activity in Cardiac Growth (2009) (38)
- Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis (2013) (38)
- Single-Cell Lineage Tracing Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification. (2016) (37)
- beta1 integrin and organized actin filaments facilitate cardiomyocyte-specific RhoA-dependent activation of the skeletal alpha-actin promoter. (2001) (37)
- Epistatic Rescue of Nkx2.5 Adult Cardiac Conduction Disease Phenotypes by Prospero-Related Homeobox Protein 1 and HDAC3 (2012) (37)
- Enhanced animal growth via ligand regulated GHRH myogenic injectable vectors (2002) (36)
- Inactivation of Cdc42 in neural crest cells causes craniofacial and cardiovascular morphogenesis defects. (2013) (35)
- Brief Report: Oct4 and Canonical Wnt Signaling Regulate the Cardiac Lineage Factor Mesp1 Through a Tcf/Lef‐Oct4 Composite Element (2013) (34)
- Intervening sequences in evolution and development (1990) (33)
- Deletion of Smooth Muscle α-Actin Alters Blood–Retina Barrier Permeability and Retinal Function (2006) (33)
- Persistent IGF‐I overexpression in skeletal muscle transiently enhances DNA accretion and growth 1 (2002) (33)
- Decreased expression of smooth muscle alpha-actin results in decreased contractile function of the mouse bladder. (2004) (31)
- Expression of Insulin-like Growth Factor-I in Skeletal Muscle of Transgenic Swine (1999) (30)
- Progesterone-binding components of chick oviduct. In vitro effects of purified hormone-receptor complexes on the initiation of RNA synthesis in chromatin. (1976) (29)
- Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. (2016) (29)
- β1-Integrin and PI 3-kinase regulate RhoA-dependent activation of skeletal α-actin promoter in myoblasts (2000) (29)
- The chicken skeletal alpha-actin gene promoter region exhibits partial dyad symmetry and a capacity to drive bidirectional transcription (1988) (29)
- Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1 gene activity (2007) (28)
- Genome‐Wide Identification of MESP1 Targets Demonstrates Primary Regulation Over Mesendoderm Gene Activity (2015) (28)
- Identification of a novel role of ZIC3 in regulating cardiac development. (2006) (28)
- Overexpression of IGF-I in skeletal muscle of transgenic mice does not prevent unloading-induced atrophy. (1998) (27)
- Long-term insulin-like growth factor-I expression in skeletal muscles attenuates the enhanced in vitro proliferation ability of the resident satellite cells in transgenic mice (2001) (27)
- Protein Tyrosine Phosphatase-Like A Regulates Myoblast Proliferation and Differentiation through MyoG and the Cell Cycling Signaling Pathway (2011) (27)
- Cytoplasmic β‐actin promoter produces germ cell and preimplantation embryonic transgene expression (1993) (26)
- A cell-autonomous role of Cited2 in controlling myocardial and coronary vascular development (2012) (26)
- Functional analysis of limb transcriptional enhancers in the mouse (2014) (25)
- Phased cis-acting promoter elements interact at short distances to direct avian skeletal alpha-actin gene transcription. (1991) (25)
- Mesp1 Marked Cardiac Progenitor Cells Repair Infarcted Mouse Hearts (2013) (25)
- Increased level and duration of expression in muscle by co-expression of a transactivator using plasmid systems (1999) (25)
- Mouse myofibers lacking the SMYD1 methyltransferase are susceptible to atrophy, internalization of nuclei and myofibrillar disarray (2016) (25)
- Developmental expression of serum response factor in the rat central nervous system. (2002) (25)
- Delimitation andCharacterization ofcis-Acting DNA Sequences Required fortheRegulated Expression andTranscriptional Control oftheChicken Skeletal ox-Actin Gene (1986) (24)
- Post-Translational Modification (2020) (24)
- Steroid control of genomic expression in embryonic chick retina. (1972) (24)
- Novel phosphorylation target in the serum response factor MADS box regulates alpha-actin transcription. (2003) (24)
- Skeletal muscle protein and amino acid metabolism in hereditary mouse muscular dystrophy. Accelerated protein turnover and increased alanine and glutamine formation and release. (1980) (23)
- Thymosin beta 4 is essential for coronary vessel development and promotes neovascularisation via adult epicardium (2007) (23)
- Control of glutamine synthetase synthesis in the embryonic chick neural retina. A caution in the use of actinomycin D. (1973) (22)
- Regulation of muscle differentiation: isolation and purification of chick actin messenger ribonucleic acid and quantitation with complementary deoxyribonucleic acid probes. (1980) (21)
- Hhex and Cer1 Mediate the Sox17 Pathway for Cardiac Mesoderm Formation in Embryonic Stem Cells (2014) (21)
- Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis (2016) (20)
- Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development (2018) (20)
- Mice harboring Gnrhr E90K, a mutation that causes protein misfolding and hypogonadotropic hypogonadism in humans, exhibit testis size reduction and ovulation failure. (2012) (19)
- Transient cardiac expression of the tinman-family homeobox gene, XNkx2-10 (2000) (19)
- Brief report: SRF‐dependent MiR‐210 silences the sonic hedgehog signaling during cardiopoesis (2013) (18)
- Using proteases to avoid false identification of DNA-protein complexes in gel shift assays. (1992) (17)
- beta(1)-integrin and PI 3-kinase regulate RhoA-dependent activation of skeletal alpha-actin promoter in myoblasts. (2000) (17)
- Expression of Nkx2‐5‐GFP bacterial artificial chromosome transgenic mice closely resembles endogenous Nkx2‐5 gene activity (2003) (17)
- Serum Response Factor-NK Homeodomain Factor Interactions, Role in Cardiac Development (1999) (17)
- Fkbp 1 a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch 1 activity (2013) (16)
- Regulation of alternative polyadenylation by Nkx2-5 and Xrn2 during mouse heart development (2016) (16)
- Expression of an Nkx3.1‐CRE gene using ROSA26 reporter mice (2006) (16)
- Isolation and purification of a hen nuclear oestrogen receptor and its effect on transcription of chick chromatin. (1979) (15)
- Differentiation of pharyngeal endoderm from mouse embryonic stem cell. (2010) (14)
- YY1 Expression Is Sufficient for the Maintenance of Cardiac Progenitor Cell State (2017) (14)
- Regulation of tropomyosin gene expression during myogenesis (1981) (14)
- The Myogenic Regulatory Factor MRF4 Represses the Cardiac α-Actin Promoter through a Negative-acting N-terminal Protein Domain* (1996) (14)
- Protein synthesis during Ilyanassa embryogenesis. (1969) (13)
- Conversion of human cardiac progenitor cells into cardiac pacemaker-like cells. (2020) (13)
- Chips ahoy: gene expression in failing hearts surveyed by high-density microarrays. (2000) (13)
- Steroid Receptor Coactivator-2 Is a Dual Regulator of Cardiac Transcription Factor Function* (2014) (13)
- A Highly Conductive 3D Cardiac Patch Fabricated Using Cardiac Myocytes Reprogrammed from Human Adipogenic Mesenchymal Stem Cells (2020) (13)
- Nonhereditary enhancement of progeny growth. (2002) (12)
- Weighing in on heart failure: the role of SERCA2a SUMOylation. (2012) (12)
- Prox1 maintains muscle structure and growth in the developing heart (2009) (12)
- Regulatory avian skeletal α-actin directs expression of insulin-like growth factor-I to skeletal muscle of transgenic pigs (1996) (12)
- Differential detection of multiple DNA-binding complexes using dissimilar polyanion competitors (1992) (12)
- Changes in Protein Synthesis in the Morphogenesis of Fundulus heteroclitus (1973) (12)
- Targeted Expression of Cre Recombinase Provokes Placental-Specific DNA Recombination in Transgenic Mice (2012) (11)
- Steroid hormone receptor fraction stimulation of RNA synthesis: a caution. (1976) (11)
- Correction: MicroRNA-17-92, a Direct Ap-2α Transcriptional Target, Modulates T-Box Factor Activity in Orofacial Clefting (2013) (11)
- 3D Bioprinting the Cardiac Purkinje System Using Human Adipogenic Mesenchymal Stem Cell Derived Purkinje Cells (2020) (11)
- The complete sequence of the chicken alpha-cardiac actin gene: a highly conserved vertebrate gene. (1985) (11)
- EFFECT OF PROGESTERONE RECEPTORS ON TRANSCRIPTION * (1977) (10)
- HIRA deficiency in muscle fibers causes hypertrophy and susceptibility to oxidative stress (2017) (10)
- Carcass composition and skeletal muscle morphology of swine expressing an insulin-like growth factor I transgene § (2007) (10)
- The CSRP2BP histone acetyltransferase drives smooth muscle gene expression (2016) (10)
- Electrical Stimulation of Artificial Heart Muscle: A Look Into the Electrophysiologic and Genetic Implications (2017) (10)
- PKG-1α mediates GATA4 transcriptional activity. (2016) (9)
- CAMTA in Cardiac Hypertrophy (2006) (9)
- Transient Mesp1 expression (2013) (9)
- Differentiation of actin-containing filaments during chick skeletal myogenesis. (1979) (8)
- CRISPR‐Cas9–induced IGF1 gene activation as a tool for enhancing muscle differentiation via multiple isoform expression (2020) (7)
- Transgenic research to enhance growth and lean carcass composition in swine. (2001) (7)
- Cloning of contractile protein genes. (1983) (7)
- β‐Adrenergic stimuli and rotating suspension culture enhance conversion of human adipogenic mesenchymal stem cells into highly conductive cardiac progenitors (2019) (7)
- TGF-beta 1 and fibroblast growth factors selectively up-regulate tissue-specific fetal genes in cardiac muscle cells. (1991) (7)
- Summary Tbx 1 has a dual role in the morphogenesis of the cardiac outflow tract (2004) (6)
- Skeletal muscle myocytes undergo protein loss and reactive oxygen‐mediated NF‐κB activation in response to tumor necrosis factorα (1998) (6)
- Feature article: Discovery of vascular Rho kinase (ROCK) inhibitory peptides (2019) (6)
- Generation of Transgenic Mice that Conditionally Overexpress Tenascin-C (2021) (5)
- Heart or hand? Unmasking the basis for specific Holt-Oram phenotypes. (1999) (5)
- Persistent Noggin arrests cardiomyocyte morphogenesis and results in early in utero lethality (2015) (5)
- RERE deficiency leads to decreased expression of GATA4 and the development of ventricular septal defects (2018) (5)
- Smyd1 Orchestrates Early Heart Development Through Positive and Negative Gene Regulation (2021) (5)
- Double‐inducible gene activation system for caspase 3 and 9 in epidermis (2007) (4)
- Analysis of a CR1 (chicken repeat) sequence flanking the 5' end of the gene encoding alpha-skeletal actin. (1990) (4)
- The expression and chromatin structure of the chicken glyceraldehyde-3-phosphate dehydrogenase gene in mouse cells. (1985) (4)
- Novel phosphorylation target in the serum response factor MADS box regulates α-actin transcription (Biochemistry (2003) 42, 24, (7477-7486)) (2008) (4)
- STEMIN and YAP5SA synthetic modified mRNAs regenerate and repair infarcted mouse hearts (2022) (4)
- Identification of cis-acting regulatory elements of the chicken skeletal α-actin gene promoter (1989) (4)
- The cardiac transcription factors Nkx 2-5 and GATA-4 are mutual cofactors have been shown to alter transcription of target genes via (2013) (4)
- Vascular Smooth Muscle-Specific Gene Expression (1995) (4)
- Progesterone-receptor mediation of chromatin RNA transcription in a cell-free system. (1976) (3)
- Novel use of a polymeric chromophore in detecting sequence-specific DNA-binding proteins. (1993) (3)
- Electrical Stimulation of Artificial Heart Muscle: a look into the electrophysiological and genetic implications. (2016) (3)
- Pax 3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor out fl ow tract septation (2011) (3)
- An evolutionarily conserved motif is required in cis for cell-type restricted repression of the chicken α-smooth muscle actin gene core promoter (1987) (3)
- Associations between the Rho kinase-1 catalytic and PH domain regulatory unit. (2013) (3)
- Aberrant expression of embryonic mesendoderm factor MESP1 promotes tumorigenesis (2019) (3)
- Quantitation of actin mRNA content in muscle cell cultures. (1981) (3)
- Reprogrammed cardiac fibroblasts to the rescue of heart failure. (2012) (3)
- TheChicken Skeletal ot-Actin GenePromoter Region Exhibits Partial DyadSymmetry anda Capacity ToDrive Bidirectional Transcription (1988) (3)
- Airways in smooth muscle α-actin null mice experience a compensatory mechanism that modulates their contractile response. (2012) (3)
- Erratum: A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice (Developmental Biology (1998) 199:1 (72-79)) (1998) (3)
- MECHANISM OF STEROID HORMONE ACTION: IN VITRO CONTROL OF GENE EXPRESSION IN CHICK OVIDUCT CHROMATIN BY PURIFIED STEROID RECEPTOR COMPLEXES (1976) (3)
- The Spatiotemporal Expression of Notch1 and Numb and Their Functional Interaction during Cardiac Morphogenesis (2021) (2)
- Serum Response Factor and Co-Factors, Roles in Cardiac Development (2010) (2)
- Mutant SRF and YAP synthetic modified mRNAs drive cardiomyocyte nuclear replication (2022) (2)
- Cardiac Homing, Differentiation, and Fusion by Progenitor Cells from Adult Heart (2003) (2)
- Cardiac-Specific Ablation of G-Protein Receptor Kinase 2 Redefines Its Roles in Heart Development and (cid:1) -Adrenergic Signaling Integrative Physiology (2006) (2)
- High performance purification of glycolytic enzymes and creatine kinase from chicken breast muscle and preparation of their specific immunological probes. (1987) (2)
- RNA polymerase II C-terminal domain kinases in heart failure (2003) (2)
- Differential expression of the actin multi gene family (1981) (2)
- OVER-EXPRESSION OF IGF-I IN SKELETAL MUSCLE DOES NOT PREVENT UNLOADING-INDUCED ATROPHY 385 (1997) (2)
- GW26-e1078 A Molecular Switch Regulating Heart and Pancreatic Development (2015) (1)
- Abstract 887: Cardiac-Specific Ablation of GRK2 Re-Defines its Roles in Heart Development and Beta-Adrenergic Signaling (2006) (1)
- Author response: Regulation of alternative polyadenylation by Nkx2-5 and Xrn2 during mouse heart development (2016) (1)
- H19X‐encoded miR‐322(424)/miR‐503 regulates muscle mass by targeting translation initiation factors (2021) (1)
- Erratum: Prox1 maintains muscle structure and growth in the developing heart (Development (2008) vol. 136 (495-505)) (2009) (1)
- Long Range Regulatory Sequences Delimited by Progressive Deletions of a Mouse Nkx2-5-GFP-BAC Clone: A New Approach to Identify Distal Gene Regulators in Evolutionarily Conserved Non-Coding Sequences (2005) (1)
- TGF-β1 and fibroblast growth factors selectively up-regulate tissue-specific fetal genes in cardiac muscle cells (1991) (1)
- The All-Chemical Approach: A Solution for Converting Fibroblasts Into Myocytes. (2016) (1)
- Molecular Regulation of Cardiac Myofibrillogenesis: Roles of Serum Response Factor, Nkx2-5, and GATA-4 (2002) (1)
- Epiblastic Cited2 function explains pleiotropy and penetrance of cardiac malformation resulting from its deficiency (2007) (1)
- Regulatory elements of the chicken alpha-skeletal actin gene direct high level and tissue-specific expression of a hIGF-I cDNA in cultured myogenic cells and transgenic mice resulting in enhanced myogenesis and pronounced muscle hypertrophy (1994) (1)
- CHICKEN α-ACTIN SRE1 IS AN IMPORTANT REGULATOR DURING STRETCH OVERLOAD INDUCED HYPERTROPHY.: 24 (1995) (1)
- SKELETAL ??-ACTIN PROMOTER ACTIVITY DURING HYPERTROPHY OF CULTURED MUSCLE CELLS 599 (1996) (0)
- Abstract 19676: A Molecular Switch Regulating Heart and Pancreatic Development (2014) (0)
- Single-Cell Lineage Tracin g Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification Graphical Abstract Highlights (2016) (0)
- Cardiovascular LIM-only proteins, CRP1 and CRP2, are potent smooth muscle differentiation cofactors (2003) (0)
- Abstract 14000: miR-322/503 Cluster Drives Cardiac Differentiation by Inhibiting CUG-binding Protein 1 (2014) (0)
- Targeting of gene expression to skeletal and cardiac muscle of trangenic animals. (1991) (0)
- Mechanisms of cardiac pleiotropy in Cited2 deficiency (2008) (0)
- C.B‐17 SCID mice develop epicardial calcinosis with unaltered cardiac function (2018) (0)
- Serum Response Factor Micro-Managing Cardiogenesis (2009) (0)
- The All-Chemical Approach (2016) (0)
- Serum response factor and are candidate trans-acting factors for basal, and growth factor-dependent transcription of the skeletal α-actin gene in cardiac muscle cells (1992) (0)
- Blood–retina barrier and retinal function are altered in smooth muscle –actin null mice (2004) (0)
- GW26-e1037 Tanshinones IIA Attenuated Oxidative Stress and Restored Balance between Pro- and Anti-inflammatory Cytokines in Hypothalamic Paraventricular Nucleus Contribute to Sympathoexcitation in Chronic High-Salt Intake Induced Hypertension (2015) (0)
- The Chicken Skeletal ot-Actin Gene Promoter Region Exhibits (0)
- Cardiac-specific deletion of Cited2 reveals a cell autonomous role in positively regulating vegfa expression in the developing heart (2007) (0)
- Regulation ofTropomyosin GeneExpression During Myogenesis (1981) (0)
- Abstract 290: Haemogenic Endocardium Contribute To Definitive Hematopoiesis During Cardiogenesis (2013) (0)
- Abstract 5437: MESP1 cooperates with loss of ARF in malignant transformation (2018) (0)
- The TGFbeta-activated kinase, TAK1, is activated in the myocardium by pressure-overload and is sufficient to trigger heart failure in transgenic mice (1999) (0)
- GH/IGF-I Transgene Expression on Muscle Homeostasis (1999) (0)
- Direct reprogramming of cardiomyocytes into cardiac Purkinje-like cells (2022) (0)
- Abstract 1066: Serum Response Factor Orchestrates Cardiac Myogenesis: Advanced from Embryonic Models to ES Cell Rescue in a Cofactor Specific Fashion (2006) (0)
- The skeletal α-actin gene promoter is regulated by combinatorial and possible competitive interactions between cis-acting elements (1990) (0)
- in situ localization of actin mRNA in early avian embryos (1987) (0)
- United States Patent ( 19 ) Schwartz et al . ( 54 ) MYOGENIC VECTOR SYSTEMS 75 ) Inventors : (2017) (0)
- and man Developmental anatomy of the heart: a tale of mice (2015) (0)
- Conversion of adipogenic mesenchymal stem cells into mature cardiac myocytes (2015) (0)
- Correction for Lin et al., “Protein Tyrosine Phosphatase-Like A Regulates Myoblast Proliferation and Differentiation through MyoG and the Cell Cycling Signaling Pathway” (2017) (0)
- Glycolytic enzymes gene expression in myogenesis purification of enzymes and immunological probes (1983) (0)
- 137 A cited2->Vegfa pathway couples myocardial and coronary vascular growth in the developing mouse heart (2011) (0)
- TNF-?? ACCELERATES DIFFERENTIATION OF SKELETAL MUSCLE MYOBLASTS (1999) (0)
- Modulation of cardiac phenotype by transforming and fibroblast growth factors resembles the induction of fetal cardiac genes during pressure-overload hypertrophy (1991) (0)
- 3SY07-2 Cardiovascular LIM-only proteins are potent transcription coadaptor proteins that promote smooth muscle differentiation (2003) (0)
- Growth factor signal transduction in the cardiac myocyte: functions of the serum response element (1993) (0)
- Response to Zhao and Huang's Commentary Letter, "Conversion of Human Cardiac Progenitor Cells using Reprogramming Factors into Heterogeneous Cardiac Pacemaker-like Cells", regarding our Manuscript on the: Conversion of Human Cardiac Progenitor Cells into Cardiac Pacemaker-like Cells. (2020) (0)
- Effects of steroid hormone receptors on gene transcription. (1977) (0)
- Cardiac Gene Expression Binding Targets: Role for Regulating Early GATA-4 and Nkx-2.5 Coactivate Nkx-2 DNA (2013) (0)
- REGION D'ACTIVATEUR MUTEE PROVENANT DU GENE D'ACTINE α DU SQUELETTE DE POULET (1990) (0)
- Abstract 578: Hex is Essential for Cardiac Myogenesis in Differentiating Embryonic Stem Cells (2007) (0)
- Abstract 473: Genetic Fate Mapping Identifies Second Heart Field Epicardial Progenitor Cells as a Source of Adipocytes in Arrhythmogenic Right Ventricular Cardiomyopathy (2008) (0)
- Regulation of transcription of the eucaryotic genome. (1976) (0)
- Pro-Epicardial Cells are Heterogeneous with Specified Smooth Muscle-Like and Pacemaker Progenitor Cells (2021) (0)
- Abstract 226: Mutual Interactive Factors β-Catenin and Oct4 Regulate Mesp1 Transcription (2012) (0)
- Abstract 18239: Yy1 Expression is Sufficient for the Mantenance of Cardiac Progenitor Cell State (2014) (0)
- Mutations in the muscle LIM protein (MLP) gene in dilated cardiomyopathy (2004) (0)
- Combination of Closely Associated Positive and Negative cis-Acting Promoter Elements Regulates Transcription (0)
- Abstract 311: Genome-wide Dissection of Wnt- and BMP-dependent Pathways: Identification of Sox17 as Essential for Cardiac Myocyte Formation by Embryonic Stem Cells (2006) (0)
- A CAUTION IN THE USE OF ACTINOMYCIN D Control of Glutamine Synthetase Synthesis in the Embryonic Chick Neural Retina (2002) (0)
- The Role of GH/IGF-I Axis in Muscle Homeostasis During Weightlessness (1997) (0)
- 531 CHIMERIC GENE EXPRESSION FROM ELEMENTS IN THE FIRST 98 BASE PAIRS OF THE ??-ACTIN PROMOTER DURING HYPERTROPHY (1994) (0)
- Transient Transgenics: An Efficient Method to Identify Gene Regulatory Elements. (2021) (0)
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What Schools Are Affiliated With Robert J Schwartz?
Robert J Schwartz is affiliated with the following schools:
