Robert A. Lamb
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British American virologist
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Biology
Robert A. Lamb's Degrees
- PhD Microbiology University of California, San Francisco
- Bachelors Biology University of California, Santa Cruz
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Why Is Robert A. Lamb Influential?
(Suggest an Edit or Addition)According to Wikipedia, Robert A. Lamb was a British-American virologist. He was the Kenneth F. Burgess Professor at Northwestern University and since 1991, an investigator of the Howard Hughes Medical Institute. From 1990 to 2016, he was the John Evans Professor of Molecular and Cellular Biology at Northwestern University.
Robert A. Lamb's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Orthomyxoviridae: The Viruses and Their Replication. (1996) (3134)
- Influenza virus M2 protein has ion channel activity (1992) (1187)
- Influenza virus assembly and budding. (2011) (622)
- Influenza A virus M2 protein: monoclonal antibody restriction of virus growth and detection of M2 in virions (1988) (540)
- Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block (1993) (498)
- Influenza Virus M2 Protein Mediates ESCRT-Independent Membrane Scission (2010) (487)
- Folding and assembly of viral membrane proteins. (1993) (473)
- Paramyxovirus fusion: a hypothesis for changes. (1993) (442)
- Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation (2006) (399)
- A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity (2008) (398)
- The gene structure and replication of influenza virus. (1983) (394)
- The M2 Proton Channels of Influenza A and B Viruses* (2006) (393)
- Taxonomy of the order Mononegavirales: update 2016 (2016) (389)
- Influenza Virus Assembly and Lipid Raft Microdomains: a Role for the Cytoplasmic Tails of the Spike Glycoproteins (2000) (385)
- Structural basis for paramyxovirus-mediated membrane fusion. (1999) (385)
- Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion (2003) (361)
- Two mRNAs that differ by two nontemplated nucleotides encode the amino coterminal proteins P and V of the paramyxovirus SV5 (1988) (350)
- Influenza virus M2 integral membrane protein is a homotetramer stabilized by formation of disulfide bonds. (1991) (345)
- A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity. (1997) (345)
- Influenza virus M2 protein is an integral membrane protein expressed on the infected-cell surface (1985) (344)
- Influenza virus M2 protein is an integral membrane protein expressed on the infected-cell surface. (1985) (331)
- Sequences of mRNAs derived from genome RNA segment 7 of influenza virus: colinear and interrupted mRNAs code for overlapping proteins. (1981) (315)
- Influenza Virus Hemagglutinin and Neuraminidase, but Not the Matrix Protein, Are Required for Assembly and Budding of Plasmid-Derived Virus-Like Particles (2007) (308)
- Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein. (2005) (300)
- Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion (2001) (295)
- Mechanisms for enveloped virus budding: can some viruses do without an ESCRT? (2008) (292)
- Influenza A virus M2 ion channel protein: a structure-function analysis (1994) (287)
- The synthesis of sendai virus polypeptides in infected cells. (1977) (284)
- Influenza A virus NS1 protein binds p85β and activates phosphatidylinositol-3-kinase signaling (2006) (279)
- Influenza virus hemagglutinin and neuraminidase cytoplasmic tails control particle shape (1997) (265)
- Structural basis of viral invasion: lessons from paramyxovirus F. (2007) (262)
- Sequence of interrupted and uninterrupted mRNAs and cloned DNA coding for the two overlapping nonstructural proteins of influenza virus (1980) (249)
- Activation of the M2 ion channel of influenza virus: a role for the transmembrane domain histidine residue. (1995) (248)
- The Influenza Virus M2 Protein Cytoplasmic Tail Interacts with the M1 Protein and Influences Virus Assembly at the Site of Virus Budding (2008) (246)
- Influenza A Virus M2 Ion Channel Activity Is Essential for Efficient Replication in Tissue Culture (2002) (244)
- Paramyxovirus membrane fusion: Lessons from the F and HN atomic structures (2005) (241)
- Passively transferred monoclonal antibody to the M2 protein inhibits influenza A virus replication in mice (1990) (241)
- Genes and Proteins of the Influenza Viruses (1989) (238)
- The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2. (2001) (238)
- Taxonomy of the order Mononegavirales: update 2019 (2019) (237)
- Taxonomy of the order Mononegavirales: update 2017 (2017) (236)
- The Gate of the Influenza Virus M2 Proton Channel Is Formed by a Single Tryptophan Residue* (2002) (226)
- Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus (2010) (217)
- Influenza virus assembly and budding in raft-derived microdomains: a quantitative analysis of the surface distribution of HA, NA and M2 proteins. (2005) (214)
- Evidence for a ninth influenza viral polypeptide. (1978) (211)
- The V proteins of simian virus 5 and other paramyxoviruses inhibit induction of interferon-beta. (2002) (211)
- Textbook of Influenza (2013) (208)
- The M1 and M2 proteins of influenza A virus are important determinants in filamentous particle formation. (1998) (207)
- Recovery of infectious SV5 from cloned DNA and expression of a foreign gene. (1997) (205)
- The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly. (2014) (204)
- Polypeptides specified by the influenza virus genome I. Evidence for eight distinct gene products specified by fowl plague virus. (1976) (201)
- The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus (1996) (199)
- Recovery of paramyxovirus simian virus 5 with a V protein lacking the conserved cysteine-rich domain: the multifunctional V protein blocks both interferon-beta induction and interferon signaling. (2002) (193)
- Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus (2013) (193)
- The remarkable coding strategy of borna disease virus: a new member of the nonsegmented negative strand RNA viruses. (1995) (192)
- Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose. (2005) (189)
- Biological activity of paramyxovirus fusion proteins: factors influencing formation of syncytia (1992) (184)
- A core trimer of the paramyxovirus fusion protein: parallels to influenza virus hemagglutinin and HIV-1 gp41. (1998) (183)
- Influenza Virus M2 Ion Channel Protein Is Necessary for Filamentous Virion Formation (2010) (182)
- Measles and subacute sclerosing panencephalitis virus proteins: lack of antibodies to the M protein in patients with subacute sclerosing panencephalitis. (1979) (178)
- ICTV Virus Taxonomy Profile: Pneumoviridae. (2017) (178)
- Identification of a second protein (M2) encoded by RNA segment 7 of influenza virus. (1981) (176)
- Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel (2008) (169)
- Segment 8 of the influenza virus genome is unique in coding for two polypeptides. (1979) (164)
- Evidence for a New Viral Late-Domain Core Sequence, FPIV, Necessary for Budding of a Paramyxovirus (2005) (158)
- Characterization of the influenza virus M2 integral membrane protein and expression at the infected-cell surface from cloned cDNA (1985) (156)
- Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel (2009) (156)
- The paramyxovirus SV5 V protein binds two atoms of zinc and is a structural component of virions. (1995) (155)
- Taxonomy of the order Mononegavirales: update 2018 (2018) (155)
- Requirements for Budding of Paramyxovirus Simian Virus 5 Virus-Like Particles (2002) (152)
- Fusion protein of the paramyxovirus simian virus 5: nucleotide sequence of mRNA predicts a highly hydrophobic glycoprotein. (1984) (152)
- Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk (2011) (151)
- The active oligomeric state of the minimalistic influenza virus M2 ion channel is a tetramer. (1997) (151)
- Ion selectivity and activation of the M2 ion channel of influenza virus. (1996) (151)
- Virology: A class act (2004) (150)
- Synthesis of influenza virus proteins in infected cells: translation of viral polypeptides, including three P polypeptides, from RNA produced by primary transcription. (1976) (149)
- Topology of eukaryotic type II membrane proteins: Importance of N-terminal positively charged residues flanking the hydrophobic domain (1991) (149)
- Permeation and Activation of the M2 Ion Channel of Influenza A Virus* (2000) (149)
- Intracellular maturation and transport of the SV5 type II glycoprotein hemagglutinin-neuraminidase: specific and transient association with GRP78-BiP in the endoplasmic reticulum and extensive internalization from the cell surface (1989) (149)
- Influenza B virus BM2 protein has ion channel activity that conducts protons across membranes. (2003) (144)
- The V protein of the paramyxovirus SV5 interacts with damage-specific DNA binding protein. (1998) (141)
- Influenza virus M2 protein ion channel activity stabilizes the native form of fowl plague virus hemagglutinin during intracellular transport (1994) (141)
- Mechanism for Proton Conduction of the M2 Ion Channel of Influenza A Virus* (2000) (138)
- Influenza Virus Hemagglutinin (H3 Subtype) Requires Palmitoylation of Its Cytoplasmic Tail for Assembly: M1 Proteins of Two Subtypes Differ in Their Ability To Support Assembly (2005) (135)
- Fusion protein of the paramyxovirus SV5: destabilizing and stabilizing mutants of fusion activation. (2000) (135)
- ICTV Virus Taxonomy Profile: Paramyxoviridae (2019) (132)
- The synthesis of Sendai virus polypeptides in infected cells. III. Phosphorylation of polypeptides. (1977) (131)
- Escaping from the cell: assembly and budding of negative-strand RNA viruses. (2004) (131)
- Filamentous Influenza Virus Enters Cells via Macropinocytosis (2012) (130)
- Virus Membrane Fusion Proteins: Biological Machines that Undergo a Metamorphosis (2000) (129)
- RNA editing by G-nucleotide insertion in mumps virus P-gene mRNA transcripts (1990) (129)
- Expression at the cell surface of biologically active fusion and hemagglutinin/neuraminidase proteins of the paramyxovirus simian virus 5 from cloned cDNA. (1985) (128)
- Hemagglutinin-neuraminidase protein of the paramyxovirus simian virus 5: nucleotide sequence of the mRNA predicts an N-terminal membrane anchor (1985) (126)
- Eukaryotic coupled translation of tandem cistrons: identification of the influenza B virus BM2 polypeptide. (1990) (126)
- Studies on the fusion peptide of a paramyxovirus fusion glycoprotein: roles of conserved residues in cell fusion (1992) (126)
- The Influenza Virus RNA Segments and Their Encoded Proteins (1983) (125)
- Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2. (2011) (125)
- Activation of paramyxovirus membrane fusion and virus entry. (2014) (124)
- Initial structural and dynamic characterization of the M2 protein transmembrane and amphipathic helices in lipid bilayers (2003) (124)
- Different roles of individual N-linked oligosaccharide chains in folding, assembly, and transport of the simian virus 5 hemagglutinin-neuraminidase (1990) (123)
- Influenza virus assembly and budding at the viral budozone. (2005) (122)
- A previously unrecognized influenza B virus glycoprotein from a bicistronic mRNA that also encodes the viral neuraminidase. (1983) (119)
- Cu(II) Inhibition of the Proton Translocation Machinery of the Influenza A Virus M2 Protein* (1999) (117)
- The Paramyxovirus Simian Virus 5 V Protein Slows Progression of the Cell Cycle (2000) (115)
- Analysis of the posttranslational modifications of the influenza virus M2 protein (1995) (115)
- Growth restriction of influenza A virus by M2 protein antibody is genetically linked to the M1 protein. (1989) (113)
- Quantitative measurement of paramyxovirus fusion: differences in requirements of glycoproteins between simian virus 5 and human parainfluenza virus 3 or Newcastle disease virus (1995) (108)
- Mapping of the two overlapping genes for polypeptides NS1 and NS2 on RNA segment 8 of influenza virus genome. (1980) (107)
- Direct measurement of the influenza A virus M2 protein ion channel activity in mammalian cells. (1994) (107)
- Influenza A Virus Uses Intercellular Connections To Spread to Neighboring Cells (2014) (107)
- A dual-functional paramyxovirus F protein regulatory switch segment (2003) (106)
- The polypeptides of canine distemper virus: synthesis in infected cells and relatedness to the polypeptides of other morbilliviruses. (1980) (105)
- Characterization of the membrane association of the influenza virus matrix protein in living cells. (1996) (105)
- The SH Integral Membrane Protein of the Paramyxovirus Simian Virus 5 Is Required To Block Apoptosis in MDBK Cells (2001) (104)
- The presence of actin in enveloped viruses (1976) (104)
- Polypeptide Synthesis in Simian Virus 5-Infected Cells (1977) (104)
- The molecular biology of influenza viruses and paramyxoviruses (1993) (103)
- Functional studies and modeling of pore-lining residue mutants of the influenza a virus M2 ion channel. (2010) (103)
- Conservation of the influenza virus membrane protein (M1) amino acid sequence and an open reading frame of RNA segment 7 encoding a second protein (M2) in H1N1 and H3N2 strains. (1981) (102)
- Do Vpu and Vpr of human immunodeficiency virus type 1 and NB of influenza B virus have ion channel activities in the viral life cycles? (1997) (102)
- The influenza virus hemagglutinin cytoplasmic tail is not essential for virus assembly or infectivity. (1994) (101)
- Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus. (2009) (100)
- Viral and cellular small integral membrane proteins can modify ion channels endogenous to Xenopus oocytes. (1995) (99)
- Identification and predicted sequence of a previously unrecognized small hydrophobic protein, SH, of the paramyxovirus simian virus 5 (1985) (98)
- Ability of the hydrophobic fusion-related external domain of a paramyxovirus F protein to act as a membrane anchor (1987) (96)
- Analysis and gene assignment of mRNAs of a paramyxovirus, simian virus 5. (1984) (96)
- Refolding of a paramyxovirus F protein from prefusion to postfusion conformations observed by liposome binding and electron microscopy (2006) (96)
- Controlling influenza virus replication by inhibiting its proton channel. (2007) (96)
- Single Amino Acid Substitution in the V Protein of Simian Virus 5 Differentiates Its Ability To Block Interferon Signaling in Human and Murine Cells (2001) (93)
- The cytoplasmic tails of the influenza virus spike glycoproteins are required for normal genome packaging. (2000) (93)
- Effects of antibody to the influenza A virus M2 protein on M2 surface expression and virus assembly. (1995) (93)
- Bimolecular Complementation of Paramyxovirus Fusion and Hemagglutinin-Neuraminidase Proteins Enhances Fusion: Implications for the Mechanism of Fusion Triggering (2009) (92)
- Chemical Rescue of Histidine Selectivity Filter Mutants of the M2 Ion Channel of Influenza A Virus* (2005) (91)
- Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein (2012) (91)
- Structure of the Newcastle disease virus F protein in the post-fusion conformation. (2010) (90)
- Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus. (2013) (89)
- Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein–RNA complex (2015) (86)
- Spliced and unspliced messenger RNAs synthesized from cloned influenza virus M DNA in an SV40 vector: expression of the influenza virus membrane protein (M1). (1982) (85)
- Infection with paramyxoviruses stimulates synthesis of cellular polypeptides that are also stimulated in cells transformed by Rous sarcoma virus or deprived of glucose. (1978) (85)
- Activation of a paramyxovirus fusion protein is modulated by inside-out signaling from the cytoplasmic tail. (2004) (84)
- Virus Replication in Engineered Human Cells That Do Not Respond to Interferons (2003) (84)
- Sequence of RNA segment 7 of the influenza B virus genome: partial amino acid homology between the membrane proteins (M1) of influenza A and B viruses and conservation of a second open reading frame. (1982) (83)
- Determination of the orientation of an integral membrane protein and sites of glycosylation by oligonucleotide-directed mutagenesis: influenza B virus NB glycoprotein lacks a cleavable signal sequence and has an extracellular NH2-terminal region (1986) (83)
- Structure and Mutagenesis of the Parainfluenza Virus 5 Hemagglutinin-Neuraminidase Stalk Domain Reveals a Four-Helix Bundle and the Role of the Stalk in Fusion Promotion (2011) (80)
- Expression of the influenza A virus M2 protein is restricted to apical surfaces of polarized epithelial cells (1992) (80)
- Palmitylation of the influenza virus hemagglutinin (H3) is not essential for virus assembly or infectivity (1996) (79)
- Complete nucleotide sequence of the neuraminidase gene of influenza B virus. (1982) (78)
- Influenza B virus genome: sequences and structural organization of RNA segment 8 and the mRNAs coding for the NS1 and NS2 proteins (1982) (78)
- Studies with cross-linking reagents on the oligomeric form of the paramyxovirus fusion protein. (1994) (78)
- Truncation of the COOH-terminal region of the paramyxovirus SV5 fusion protein leads to hemifusion but not complete fusion (1996) (77)
- Timing is everything: Fine-tuned molecular machines orchestrate paramyxovirus entry (2015) (76)
- Roles for the Cytoplasmic Tails of the Fusion and Hemagglutinin-Neuraminidase Proteins in Budding of the Paramyxovirus Simian Virus 5 (2002) (75)
- Involvement of the Cytoplasmic Domain of the Hemagglutinin-Neuraminidase Protein in Assembly of the Paramyxovirus Simian Virus 5 (1999) (75)
- Influenza B virus BM2 protein is an oligomeric integral membrane protein expressed at the cell surface. (2003) (74)
- Analysis of the relationship between cleavability of a paramyxovirus fusion protein and length of the connecting peptide (1989) (74)
- Diversity of coding strategies in influenza viruses (1991) (74)
- Fusion activation by a headless parainfluenza virus 5 hemagglutinin-neuraminidase stalk suggests a modular mechanism for triggering (2012) (74)
- Flipping in the Pore: Discovery of Dual Inhibitors That Bind in Different Orientations to the Wild-Type versus the Amantadine-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel (2014) (73)
- Autophagy, apoptosis, and the influenza virus M2 protein. (2009) (73)
- Reverse genetics of negative-strand RNA viruses: closing the circle. (1999) (73)
- Membrane Fusion Promoted by Increasing Surface Densities of the Paramyxovirus F and HN Proteins: Comparison of Fusion Reactions Mediated by Simian Virus 5 F, Human Parainfluenza Virus Type 3 F, and Influenza Virus HA (1998) (71)
- The Amphipathic Helix of Influenza A Virus M2 Protein Is Required for Filamentous Bud Formation and Scission of Filamentous and Spherical Particles (2013) (71)
- Conserved Glycine Residues in the Fusion Peptide of the Paramyxovirus Fusion Protein Regulate Activation of the Native State (2004) (70)
- Integration of a small integral membrane protein, M2, of influenza virus into the endoplasmic reticulum: analysis of the internal signal- anchor domain of a protein with an ectoplasmic NH2 terminus (1988) (70)
- Effect of Cytoplasmic Tail Truncations on the Activity of the M2 Ion Channel of Influenza A Virus (1999) (69)
- The synthesis of Sendai virus polypeptides in infected cells. II. Intracellular distribution of polypeptides. (1977) (67)
- Taxonomy of the order Mononegavirales: second update 2018 (2019) (66)
- Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus. (2011) (66)
- Influenza virus is not restricted by tetherin whereas influenza VLP production is restricted by tetherin. (2011) (65)
- Effect of mutations and deletions in a bicistronic mRNA on the synthesis of influenza B virus NB and NA glycoproteins (1989) (65)
- Structure of the Human Metapneumovirus Fusion Protein with Neutralizing Antibody Identifies a Pneumovirus Antigenic Site (2012) (65)
- The influenza virus M2 ion channel protein: probing the structure of the transmembrane domain in intact cells by using engineered disulfide cross-linking. (1999) (64)
- Determination by peptide mapping of the unique polypeptides in Sendai virions and infected cells. (1978) (64)
- Structure of the Parainfluenza Virus 5 (PIV5) Hemagglutinin-Neuraminidase (HN) Ectodomain (2013) (63)
- Death by influenza virus protein (2001) (62)
- The paramyxovirus SV5 small hydrophobic (SH) protein is not essential for virus growth in tissue culture cells. (1998) (62)
- Analysis in vivo of GRP78-BiP/substrate interactions and their role in induction of the GRP78-BiP gene. (1992) (61)
- Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation (2020) (61)
- Functional Analysis of the Transmembrane Domain in Paramyxovirus F Protein-Mediated Membrane Fusion (2008) (61)
- Flux of the paramyxovirus hemagglutinin-neuraminidase glycoprotein through the endoplasmic reticulum activates transcription of the GRP78-BiP gene (1991) (61)
- Fusion Activation through Attachment Protein Stalk Domains Indicates a Conserved Core Mechanism of Paramyxovirus Entry into Cells (2014) (60)
- Molecular mechanisms of antiviral resistance. (1995) (60)
- Alterations to influenza virus hemagglutinin cytoplasmic tail modulate virus infectivity (1992) (59)
- The interplay of functional tuning, drug resistance, and thermodynamic stability in the evolution of the M2 proton channel from the influenza A virus. (2008) (59)
- Structure of the Ulster Strain Newcastle Disease Virus Hemagglutinin-Neuraminidase Reveals Auto-Inhibitory Interactions Associated with Low Virulence (2012) (59)
- Capture and imaging of a prehairpin fusion intermediate of the paramyxovirus PIV5 (2011) (59)
- Recombinant parainfluenza virus 5 (PIV5) expressing the influenza A virus hemagglutinin provides immunity in mice to influenza A virus challenge. (2007) (59)
- Analysis of the Pore Structure of the Influenza A Virus M2 Ion Channel by the Substituted-Cysteine Accessibility Method (2000) (58)
- The role of the cytoplasmic tail region of influenza virus hemagglutinin in formation and growth of fusion pores. (1997) (58)
- Conserved Cysteine-Rich Domain of Paramyxovirus Simian Virus 5 V Protein Plays an Important Role in Blocking Apoptosis (2004) (58)
- 16 The Influenza A Virus M2 Ion Channel Protein and Its Role in the Influenza Virus Life Cycle (1994) (57)
- A specific sub-set of host-cell mRNAs prime influenza virus mRNA synthesis. (1984) (57)
- Easily Accessible Polycyclic Amines that Inhibit the Wild-Type and Amantadine-Resistant Mutants of the M2 Channel of Influenza A Virus (2014) (56)
- Comparison of the relative roles of the F and HN surface glycoproteins of the paramyxovirus simian virus 5 in inducing protective immunity (1987) (56)
- Paramyxovirus fusion (F) protein: a conformational change on cleavage activation. (2001) (56)
- Synthesis of influenza virus polypeptides in cells resistant to alpha-amanitin: evidence for the involvement of cellular RNA polymerase II in virus replication (1977) (56)
- Cell surface expression and orientation in membranes of the 44-amino-acid SH protein of simian virus 5 (1988) (55)
- Deletion of the Cytoplasmic Tail of the Fusion Protein of the Paramyxovirus Simian Virus 5 Affects Fusion Pore Enlargement (2001) (54)
- The CM2 protein of influenza C virus is an oligomeric integral membrane glycoprotein structurally analogous to influenza A virus M2 and influenza B virus NB proteins. (1997) (54)
- Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus (2017) (53)
- Domain architecture and oligomerization properties of the paramyxovirus PIV 5 hemagglutinin-neuraminidase (HN) protein. (2008) (52)
- Role of NH2-terminal positively charged residues in establishing membrane protein topology. (1993) (52)
- Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form (2015) (52)
- An amantadine-sensitive chimeric BM2 ion channel of influenza B virus has implications for the mechanism of drug inhibition (2009) (51)
- Expression and initial structural insights from solid-state NMR of the M2 proton channel from influenza A virus. (2002) (51)
- Characterization of inhibition of M2 ion channel activity by BL-1743, an inhibitor of influenza A virus (1996) (51)
- Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel. (2011) (51)
- Influenza virus proton channels. (2006) (51)
- Inhibitors of the Influenza A Virus M2 Proton Channel Discovered Using a High-Throughput Yeast Growth Restoration Assay (2013) (49)
- Identification of the Pore-lining Residues of the BM2 Ion Channel Protein of Influenza B Virus* (2008) (48)
- Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus. (2011) (48)
- Monitoring single-cell infectivity from virus-particle nanoarrays fabricated by parallel dip-pen nanolithography. (2007) (48)
- The paramyxovirus fusion protein forms an extremely stable core trimer: structural parallels to influenza virus haemagglutinin and HIV-1 gp41. (1999) (47)
- Understanding the mechanism of action of the anti-influenza virus drug amantadine. (1995) (47)
- Influenza C virus CM2 integral membrane glycoprotein is produced from a polypeptide precursor by cleavage of an internal signal sequence. (1998) (47)
- Paramyxovirus fusion protein: characterization of the core trimer, a rod-shaped complex with helices in anti-parallel orientation. (1999) (46)
- Viral membrane scission. (2013) (46)
- Influenza B virus NB glycoprotein is a component of the virion. (1996) (46)
- Expression of unspliced NS1 mRNA, spliced NS2 mRNA, and a spliced chimera mRNA from cloned influenza virus NS DNA in an SV40 vector. (1984) (46)
- Reconstitution of the influenza virus M2 ion channel in lipid bilayers (1994) (46)
- In vitro synthesis of structural and nonstructural proteins of Sendai and SV5 viruses. (1980) (45)
- Paramyxovirus fusion (F) protein and hemagglutinin-neuraminidase (HN) protein interactions: intracellular retention of F and HN does not affect transport of the homotypic HN or F protein. (1997) (45)
- Mutations in the Parainfluenza Virus 5 Fusion Protein Reveal Domains Important for Fusion Triggering and Metastability (2013) (45)
- Polylactosaminoglycan modification of a small integral membrane glycoprotein, influenza B virus NB (1988) (45)
- Individual roles of N-linked oligosaccharide chains in intracellular transport of the paramyxovirus SV5 fusion protein. (1995) (44)
- 3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant. (2013) (44)
- Lateral Organization of Influenza Virus Proteins in the Budozone Region of the Plasma Membrane (2017) (44)
- Comparison of differing cytopathic effects in human airway epithelium of parainfluenza virus 5 (W3A), parainfluenza virus type 3, and respiratory syncytial virus. (2011) (41)
- Probing the paramyxovirus fusion (F) protein-refolding event from pre- to postfusion by oxidative footprinting (2014) (40)
- Nucleotide sequences of influenza A virus RNA segment 7: a comparison of five isolates. (1989) (40)
- The phosphorylation of sendai virus proteins by a virus particle-associated protein kinase. (1975) (39)
- Molecular cloning of the NP and L genes of simian virus 5: identification of highly conserved domains in paramyxovirus NP and L proteins. (1992) (39)
- Defective assembly and intracellular transport of mutant paramyxovirus hemagglutinin-neuraminidase proteins containing altered cytoplasmic domains (1990) (38)
- Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins. (2007) (36)
- Influenza virus budding does not require a functional AAA+ ATPase, VPS4. (2010) (35)
- Influenza B virus RNA segment 8 codes for two nonstructural proteins. (1981) (35)
- The RNA binding region of the paramyxovirus SV5 V and P proteins. (1997) (33)
- Conversion of a class II integral membrane protein into a soluble and efficiently secreted protein: multiple intracellular and extracellular oligomeric and conformational forms (1990) (33)
- The Oligomeric State of the Active BM2 Ion Channel Protein of Influenza B Virus* (2008) (33)
- The paramyxovirus simian virus 5 hemagglutinin-neuraminidase glycoprotein, but not the fusion glycoprotein, is internalized via coated pits and enters the endocytic pathway. (1996) (31)
- Proper spacing between heptad repeat B and the transmembrane domain boundary of the paramyxovirus SV5 F protein is critical for biological activity. (1997) (31)
- Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation (2017) (31)
- Folding and oligomerization properties of a soluble and secreted form of the paramyxovirus hemagglutinin-neuraminidase glycoprotein. (1990) (30)
- Functional Antibody Arrays through Metal Ion‐Affinity Templates (2006) (30)
- Polarized Apical Targeting Directed by the Signal/Anchor Region of Simian Virus 5 Hemagglutinin-Neuraminidase* (1997) (29)
- Problems of classification in the family Paramyxoviridae (2018) (29)
- A Role for Caveolin 1 in Assembly and Budding of the Paramyxovirus Parainfluenza Virus 5 (2010) (29)
- Effect of Inserting Paramyxovirus Simian Virus 5 Gene Junctions at the HN/L Gene Junction: Analysis of Accumulation of mRNAs Transcribed from Rescued Viable Viruses (1999) (29)
- The influenza A virus spliced messenger RNA M mRNA3 is not required for viral replication in tissue culture. (2008) (28)
- Sequence characterization of the membrane protein gene of paramyxovirus simian virus 5. (1990) (28)
- Structure of the Paramyxovirus Parainfluenza Virus 5 Nucleoprotein in Complex with an Amino-Terminal Peptide of the Phosphoprotein (2017) (27)
- Cell surface expression of glycosylated, nonglycosylated, and truncated forms of a cytoplasmic protein pyruvate kinase (1988) (26)
- Asp44 stabilizes the Trp41 gate of the M2 proton channel of influenza A virus. (2013) (26)
- Transposition of domains between the M2 and HN viral membrane proteins results in polypeptides which can adopt more than one membrane orientation (1989) (24)
- A pH-dependent conformational ensemble mediates proton transport through the influenza A/M2 protein. (2010) (23)
- The Nonstructural Proteins of Paramyxoviruses (1991) (22)
- Paramyxovirus fusion: real-time measurement of parainfluenza virus 5 virus-cell fusion. (2006) (22)
- Molecular Dynamics Simulation Directed Rational Design of Inhibitors Targeting Drug-Resistant Mutants of Influenza A Virus M 2 (2011) (21)
- Unwinding with a vengeance (1989) (20)
- Analysis of the pH Requirement for Membrane Fusion of Different Isolates of the Paramyxovirus Parainfluenza Virus 5 (2006) (20)
- The Paramyxovirus Fusion Protein C-Terminal Region: Mutagenesis Indicates an Indivisible Protein Unit (2011) (20)
- Nucleotide sequence of RNA segment 7 of influenza B/Singapore/222/79: maintenance of a second large open reading frame. (1986) (19)
- Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials. (2016) (19)
- Repurposing Papaverine as an Antiviral Agent against Influenza Viruses and Paramyxoviruses (2020) (16)
- Cell Surface Expression of Biologically Active Influenza C Virus HEF Glycoprotein Expressed from cDNA (1999) (16)
- A glycine to alanine substitution in the paramyxovirus SV5 fusion peptide increases the initial rate of fusion. (1997) (16)
- Expression of influenza B virus hemagglutinin containing multibasic residue cleavage sites. (1997) (15)
- Mutants of the paramyxovirus SV5 fusion protein: regulated and extensive syncytium formation. (1995) (15)
- The signal for clathrin-mediated endocytosis of the paramyxovirus SV5 HN protein resides at the transmembrane domain-ectodomain boundary region. (1999) (14)
- Simian virus 5 membrane protein maturation: expression in virus-infected cells and from a eukaryotic vector. (1991) (14)
- Flexibility of the Head-Stalk Linker Domain of Paramyxovirus HN Glycoprotein Is Essential for Triggering Virus Fusion (2016) (14)
- A fluorescence polarization assay using an engineered human respiratory syncytial virus F protein as a direct screening platform. (2011) (13)
- Influenza virus M2 protein ion channel activity is not required to maintain the equine-1 hemagglutinin in its native form in infected cells. (1994) (13)
- The polypeptides and RNA of Sendai virus (1975) (12)
- Viral ion channels as models for ion transport and targets for antiviral drug action. (2004) (12)
- A Chimeric Pneumovirus Fusion Protein Carrying Neutralizing Epitopes of Both MPV and RSV (2016) (12)
- Effect of the host cell on early and late synthesis of influenza virus polypeptides (1978) (11)
- Reversible Inhibition of Fusion Activity of a Paramyxovirus Fusion Protein by an Engineered Disulfide Bond in the Membrane-Proximal External Region (2012) (11)
- Specific non-templated nucleotide addition to a simian virus 5 mRNA: Prediction of a common mechanism by which unrecognized hybrid P-cysteine-rich proteins are encoded by paramyxovirus "P" genes (1989) (11)
- Influenza virus ts61S hemagglutinin is significantly defective in polypeptide folding and intracellular transport at the permissive temperature. (1991) (10)
- Deadly H7N9 influenza virus: a pandemic in the making or a warning lesson? (2013) (10)
- The proton selective ion channels of influenza A and B viruses (2005) (10)
- Identification of a Membrane Targeting and Degradation Signal in the p42 Protein of Influenza C Virus (2000) (10)
- Type II integral membrane protein, TM of J paramyxovirus promotes cell-to-cell fusion (2015) (10)
- Swine-origin influenza virus and the 2009 pandemic. (2010) (9)
- Analysis of parainfluenza virus-5 hemagglutinin-neuraminidase protein mutants that are blocked in internalization and degradation. (2010) (9)
- Probing the Functions of the Paramyxovirus Glycoproteins F and HN with a Panel of Synthetic Antibodies (2014) (8)
- The Structure, Function, and Pathobiology of the Influenza A and B Virus Ion Channels. (2020) (8)
- Extinct 1918 virus comes alive (2005) (8)
- Structure of the Uncleaved Paramyxovirus (hPIV3) Fusion Protein (2005) (7)
- Fundamental Virology, 4th Edition; and Fields Virology, 4th Edition, Volumes I and II:Fundamental Virology, 4th Edition;Fields Virology, 4th Edition, Volumes I and II (2002) (7)
- SV5 and Sendai virus polypeptides: Aspects of composition, synthesis and phosphorylation (1978) (7)
- On the Stability of Parainfluenza Virus 5 F Proteins (2015) (6)
- RNA segment 8 of the influenza virus genome contains two overlapping genes: Mapping the genes for polypeptides NS1 and NS2 (1980) (6)
- In memoriam--Richard M. Elliott (1954-2015). (2015) (5)
- NONVIRAL SEQUENCES IN COMPLETE INFLUENZA VIRAL DNA CLONES AND FUNCTIONAL EXPRESSION OF CLONED DNA CODING FOR THE HEMAGGLUTININ (1981) (5)
- The M2 Proteins of Influenza A and B Viruses are Single-Pass Proton Channels (2005) (5)
- Monoclonal antibodies targeting ST2L Domain 1 or Domain 3 differentially modulate IL-33-induced cytokine release by human mast cell and basophilic cell lines. (2016) (5)
- Proton channels of influenza A and B viruses (2013) (5)
- Mutagenesis of Paramyxovirus Hemagglutinin-Neuraminidase Membrane-Proximal Stalk Region Influences Stability, Receptor Binding, and Neuraminidase Activity (2016) (5)
- The nucleotide sequence of the neuraminidase gene of influenza B virus reveals two overlapping reading frames (1983) (4)
- Structure of the Newcastle Disease Virus F Protein in the Post-Fusion Conformation (2010) (4)
- Resveratrol Inhibits Venezuelan Equine Encephalitis Virus Infection by Interfering with the AKT/GSK Pathway (2021) (4)
- Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins (2016) (4)
- Sequence comparison of paramyxovirus surface glycoproteins (1987) (4)
- The Paramyxovirus SV 5 Small Hydrophobic ( SH ) Protein Is Not Essential for Virus Growth in Tissue Culture Cells (1998) (3)
- Mutations in the parainfluenza virus 5 fusion (F) protein reveal (2013) (3)
- The Sanborn map: a tool for the geographer (1961) (3)
- GENETIC VARIATION OF INFLUENZA A VIRUSES AS STUDIED BY RECOMBINANT DNA TECHNIQUES (1980) (3)
- MULTIPLE mRNAs AND CODING REGIONS DERIVED FROM INDIVIDUAL INFLUENZA A AND B VIRUS RNA SEGMENTS (1981) (2)
- A ninth unique influenza virus-coded polypeptide. (1980) (2)
- Primary structure of the fusion protein and the hemagglutinin-neuraminidase protein of the paramyxovirus SV5 (1985) (2)
- RNA structure. Unwinding with a vengeance. (1989) (2)
- STUDIES ON THE SECOND PROTEIN ENCODED BY THE NEURAMINIDASE GENE OF INFLUENZA B VIRUS (1984) (2)
- Direct characterization of influenza viral NS1 mRNA and related sequences from infected HeLa cells and a cell-free transcription system. (1986) (2)
- The Interplay of Thermodynamic Stability, Functional Tuning, and Drug Resistance in the Evolution of the M2 Proton Channel From the Influenza A Virus (2008) (1)
- A rapid and efficient method for generating anti-variable region monoclonal antibodies using type-1 interferons as immune modulators. (2006) (1)
- Morbilliviruses and neurological diseases (1980) (1)
- Creative Financing of the Infrastructure (1984) (1)
- Effect of influenza A virus M2 protein on virus assembly and release (1996) (1)
- Electrical properties of the M2 ion channel of influenza A virus (1996) (1)
- The Fully Human Antibody CNTO1275 Effectively Inhibits Human IL-12 and IL-23 Mediated Th1 and Th17 Cell Function and Provides Clinical Benefit to Patients with Plaque Psoriasis (2007) (1)
- Expression of biologically active F and HN proteins of the paramyxovirus SV5 from cloned cDNA (1985) (1)
- Reversible inhibition of the influenza virus M2 ion channel by a spirene containing compound, BL-1743 (1996) (1)
- A genetic approach to determining glycoprotein topology: The influenza B NB glycoprotein has an extracellular NH2-terminal domain containing two N-linked carbohydrate chains (1988) (0)
- Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation (2017) (0)
- Interrupted mRNAs and overlapping genes in influenza virus (1981) (0)
- Structure–function relationship of the M2 ion channel of influenza A virus (2001) (0)
- Infection of mouse teratocarcinoma stem cells with influenza virus: normal expression of proteins derived from spliced messenger RNAs. (1983) (0)
- Crystal structure of prefusion Hendra virus F protein (2016) (0)
- Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) (pH 8.0) (2005) (0)
- Alkali blue 5B--a rapid stain for elastin. (1969) (0)
- Crystal structure of the parainfluenza virus 5 nucleoprotein-phosphoprotein complex (2017) (0)
- Crystal structure of the oligomerization domain of phosphoprotein from parainfluenza virus 5 (2020) (0)
- Crystal Structure of Soluble WR PIV5 F-GCNt (2015) (0)
- , Zachary with a Panel of Synthetic Antibodies Paramyxovirus Glycoproteins F and HN Probing the Functions of the (2014) (0)
- PARAMYXOVIRUS SV5 FUSION PROTEIN CORE (1999) (0)
- Xenopus Oocytes (2005) (0)
- High resolution optical microscopy analysis of Influenza Virus A assembly (2009) (0)
- the Role of the Stalk in Fusion Promotion Domain Reveals a Four-Helix Bundle and Hemagglutinin-Neuraminidase Stalk Parainfluenza Virus 5 Structure and Mutagenesis of the (2011) (0)
- Mapping Water Density to Design New Blockers Against a Viral Proton Channel (2012) (0)
- Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand Sialyllactose (soaked with Sialyllactose, pH8.0) (2005) (0)
- Pharmacological Relevant Amantadine Binding Site is in the Pore of Influenza a Virus M2 Proton Channel (2010) (0)
- Influenza A VirusM2Protein: Monoclonal Antibody Restriction of VirusGrowthandDetection ofM2inVirions (1988) (0)
- Structure of the parainfluenza virus 5 nucleocapsid-RNA complex: an insight into paramyxovirus polymerase activity (2015) (0)
- Mapping of the two overlapping gen on RNA segment 8 of influenza virus (Rna genes in different reading frames/nuclease SI mapping/hybr gene structure) (2016) (0)
- Analysis and design of ion channel proteins (1997) (0)
- Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with sialic acid, pH 8.0) (2005) (0)
- Studies on the structure and function of the SV5 fusion protein (1988) (0)
- Polylactosaminoglycan Modification of a Small Integral Membrane (2003) (0)
- 1 2 Structure and mutagenesis of the parainfluenza virus 5 3 hemagglutinin-neuraminidase stalk domain reveals a four-helix 4 bundle and the role of the stalk in fusion promotion 5 6 (2011) (0)
- Probing the functions of the paramyxovirus glycoproteins F and HN 3 with a panel of synthetic antibodies ( sABs ) 4 5 (2014) (0)
- INFLUENZA A VIRUSES AS STUDIED BY RECOMBINANT DNA TECHNIQUES (1982) (0)
- Determining the Functional Core for Proton Transport, Ion Selectivity and Amantadine Sensitivity of the A/M2 Protein from Influenza A Virus (2009) (0)
- Structure, modification, intracellular transport and function of influenza and paramyxovirus integral membrane proteins (1988) (0)
- Problems of classification in the family Paramyxoviridae (2018) (0)
- Editorial overview: Virus structure and functions. (2017) (0)
- Richard Ellis Ford Matthews (1921-1995) (1995) (0)
- Growthrestriction ofinfluenza A virus byM2protein antibody is genetically linked totheM1protein (1989) (0)
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Other Resources About Robert A. Lamb
What Schools Are Affiliated With Robert A. Lamb?
Robert A. Lamb is affiliated with the following schools:
- University of California, San Francisco
- University of Pennsylvania
- University of Cambridge
- University of California, Santa Cruz
- University of Texas Medical Branch
- University of Alabama
- Northwestern University
- University of Oxford
- Northwestern University
- University of Southern California
- Stanford University
- Rockefeller University
- University of Birmingham
