Robert M Hoffman

Q: What Schools Are Affiliated With Robert M Hoffman

Robert M Hoffman is affiliated with the following schools: Harvard University, University of Lübeck, University of California, Berkeley, University of Chile, University of California, San Diego, University of California, Los Angeles, Rosalind Franklin University of Medicine and Science, University of Toronto, Osaka University, Massachusetts General Hospital, University of Helsinki, Yale University, University of California, Irvine, Kitasato University, Keio University, Stanford University, Massachusetts Institute of Technology, Yokohama City University, Okayama University

Robert M Hoffman's AcademicInfluence.com Rankings

Robert M Hoffman

Physics

#1996

World Rank

#3010

Historical Rank

physics Degrees

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Physics

Robert M Hoffman's Degrees

PhD Physics University of California, Berkeley
Masters Physics University of California, Berkeley
Bachelors Physics University of California, Berkeley

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Robert M Hoffman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force (2013) (1075)
A Senescence Program Controlled by p53 and p16INK4a Contributes to the Outcome of Cancer Therapy (2002) (1012)
Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. (2010) (728)
The multiple uses of fluorescent proteins to visualize cancer in vivo (2005) (622)
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling (2011) (598)
Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases. (2000) (548)
Orthotopic Metastatic Mouse Models for Anticancer Drug Discovery and Evaluation: a Bridge to the Clinic (2004) (545)
Dissecting p53 tumor suppressor functions in vivo. (2002) (518)
Gene expression profiling predicts clinical outcome of prostate cancer. (2004) (506)
Transdifferentiation of glioblastoma cells into vascular endothelial cells (2011) (480)
Biomimetic amplification of nanoparticle homing to tumors (2007) (419)
Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons. (2005) (403)
A metastatic nude-mouse model of human pancreatic cancer constructed orthotopically with histologically intact patient specimens. (1992) (391)
Identification of Liver Cancer Progenitors Whose Malignant Progression Depends on Autocrine IL-6 Signaling (2013) (387)
Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium. (2005) (369)
Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens. (1991) (367)
Patient-derived orthotopic xenografts: better mimic of metastasis than subcutaneous xenografts (2015) (349)
Glioma tumor stem-like cells promote tumor angiogenesis and vasculogenesis via vascular endothelial growth factor and stromal-derived factor 1. (2009) (348)
Nestin expression in hair follicle sheath progenitor cells (2003) (346)
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis. (1984) (340)
Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves. (2005) (331)
Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein expression. (1997) (293)
Matrix metalloproteinase inhibitor BB-94 (batimastat) inhibits human colon tumor growth and spread in a patient-like orthotopic model in nude mice. (1994) (289)
Targeted therapy with a Salmonella typhimurium leucine-arginine auxotroph cures orthotopic human breast tumors in nude mice. (2006) (272)
Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells. (2004) (269)
Imaging exosome transfer from breast cancer cells to stroma at metastatic sites in orthotopic nude-mouse models. (2013) (265)
Development of real-time subcellular dynamic multicolor imaging of cancer-cell trafficking in live mice with a variable-magnification whole-mouse imaging system. (2006) (255)
Green fluorescent protein imaging of tumour growth, metastasis, and angiogenesis in mouse models. (2002) (244)
Increased expression of apoptosis inhibitor protein XIAP contributes to anoikis resistance of circulating human prostate cancer metastasis precursor cells. (2005) (229)
Clinical applications of the histoculture drug response assay. (1995) (229)
Monotherapy with a tumor-targeting mutant of Salmonella typhimurium cures orthotopic metastatic mouse models of human prostate cancer (2007) (225)
High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine. (1976) (222)
Whole-body imaging with fluorescent proteins (2006) (218)
Nascent blood vessels in the skin arise from nestin-expressing hair-follicle cells. (2004) (217)
Cellular expression of green fluorescent protein, coupled with high-resolution in vivo videomicroscopy, to monitor steps in tumor metastasis. (1999) (215)
A fluorescent orthotopic bone metastasis model of human prostate cancer. (1999) (213)
Potent and highly selective hypoxia-activated achiral phosphoramidate mustards as anticancer drugs. (2008) (211)
The feasibility of targeted selective gene therapy of the hair follicle (1995) (204)
Direct external imaging of nascent cancer, tumor progression, angiogenesis, and metastasis on internal organs in the fluorescent orthotopic model (2002) (200)
Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model. (2002) (198)
Dual-color fluorescence imaging distinguishes tumor cells from induced host angiogenic vessels and stromal cells (2003) (197)
Human ovarian carcinoma metastatic models constructed in nude mice by orthotopic transplantation of histologically-intact patient specimens. (1993) (197)
A new patient‐like metastatic model of human lung cancer constructed orthotopically with intact tissue via thoracotomy in immunodeficient mice (1992) (195)
Visualizing gene expression by whole-body fluorescence imaging. (2000) (193)
Subcellular imaging in the live mouse (2006) (186)
A clinically relevant, syngeneic model of spontaneous, highly metastatic B16 mouse melanoma. (2010) (186)
The metabolic defect of methionine dependence occurs frequently in human tumor cell lines. (1983) (186)
Color-coded fluorescence imaging of tumor-host interactions (2006) (186)
Infrared multiphoton microscopy: subcellular-resolved deep tissue imaging. (2009) (176)
Nude mouse metastatic models of human stomach cancer constructed using orthotopic implantation of histologically intact tissue. (1993) (174)
In vivo-like growth of human tumors in vitro. (1986) (171)
Essential Role for Activation of the Polycomb Group (PcG) Protein Chromatin Silencing Pathway in Metastatic Prostate Cancer (2006) (165)
Altered methionine metabolism occurs in all members of a set of diverse human tumor cell lines (1984) (160)
Cellular Dynamics Visualized in Live Cells in Vitro and in Vivo by Differential Dual-Color Nuclear-Cytoplasmic Fluorescent-Protein Expression (2004) (159)
Therapeutic tumor-specific cell cycle block induced by methionine starvation in vivo. (1993) (158)
Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function (2008) (151)
In vivo-like drug responses of human tumors growing in three-dimensional gel-supported primary culture. (1987) (150)
Prolonged dormancy and site-specific growth potential of cancer cells spontaneously disseminated from nonmetastatic breast tumors as revealed by labeling with green fluorescent protein. (2003) (150)
Role of connexins in metastatic breast cancer and melanoma brain colonization (2013) (150)
Nestin-linked green fluorescent protein transgenic nude mouse for imaging human tumor angiogenesis. (2005) (149)
A novel red fluorescent protein orthotopic pancreatic cancer model for the preclinical evaluation of chemotherapeutics. (2003) (149)
Selective Advantage of Resistant Strains at Trace Levels of Antibiotics: a Simple and Ultrasensitive Color Test for Detection of Antibiotics and Genotoxic Agents (2011) (149)
In vitro sensitivity assays in cancer: A review, analysis, and prognosis (1991) (148)
Characterization of HCT116 human colon cancer cells in an orthotopic model. (2008) (147)
Whole-body and intravital optical imaging of angiogenesis in orthotopically implanted tumors (2001) (146)
A metastatic orthotopic-transplant nude-mouse model of human patient breast cancer. (1993) (145)
Widespread skeletal metastatic potential of human lung cancer revealed by green fluorescent protein expression. (1998) (143)
Overactivated neddylation pathway as a therapeutic target in lung cancer. (2014) (143)
Peptides selected for binding to clotted plasma accumulate in tumor stroma and wounds. (2006) (143)
In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation (2009) (142)
Real-time in vivo dual-color imaging of intracapillary cancer cell and nucleus deformation and migration. (2005) (140)
Overexpression and large-scale production of recombinant L-methionine-alpha-deamino-gamma-mercaptomethane-lyase for novel anticancer therapy. (1997) (139)
Fluorescently labeled chimeric anti‐CEA antibody improves detection and resection of human colon cancer in a patient‐derived orthotopic xenograft (PDOX) nude mouse model (2014) (138)
Development of recombinant methioninase to target the general cancer-specific metabolic defect of methionine dependence: a 40-year odyssey (2015) (138)
CXC‐chemokine/CXCR2 biological axis promotes angiogenesis in vitro and in vivo in pancreatic cancer (2009) (137)
CT features of pulmonary alveolar proteinosis. (2001) (135)
Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models (2014) (134)
Transgenic Nude Mouse with Ubiquitous Green Fluorescent Protein Expression as a Host for Human Tumors (2004) (134)
Cancer metastasis directly eradicated by targeted therapy with a modified Salmonella typhimurium (2009) (132)
Reversible growth arrest in simian virus 40-transformed human fibroblasts. (1980) (131)
Anticancer efficacy in vivo and in vitro, synergy with 5-fluorouracil, and safety of recombinant methioninase. (1998) (130)
Hypomethylation of DNA in human cancer cells: a site-specific change in the c-myc oncogene. (1984) (129)
Successful fluorescence-guided surgery on human colon cancer patient-derived orthotopic xenograft mouse models using a fluorophore-conjugated anti-CEA antibody and a portable imaging system. (2014) (128)
Efficacy of a genetically-modified Salmonella typhimurium in an orthotopic human pancreatic cancer in nude mice. (2009) (128)
Fluorophore-conjugated anti-CEA Antibody for the Intraoperative Imaging of Pancreatic and Colorectal Cancer (2008) (125)
Nutrition and chronic lung disease. (1985) (125)
Two-photon laser-generated microtracks in 3D collagen lattices: principles of MMP-dependent and -independent collective cancer cell invasion (2011) (125)
To do tissue culture in two or three dimensions? that is the question (1993) (125)
Whole-body subcellular multicolor imaging of tumor-host interaction and drug response in real time. (2007) (123)
Monotherapy with a tumor-targeting mutant of S. typhimurium inhibits liver metastasis in a mouse model of pancreatic cancer. (2010) (123)
The bulge area is the origin of nestin‐expressing pluripotent stem cells of the hair follicle (2011) (123)
Transduction of liver cells by lentiviral vectors: analysis in living animals by fluorescence imaging. (2001) (121)
Three-dimensional histoculture: origins and applications in cancer research. (1991) (120)
Systemic targeting of primary bone tumor and lung metastasis of high-grade osteosarcoma in nude mice with a tumor-selective strain of Salmonella typhymurium (2009) (120)
In vivo color-coded imaging of the interaction of colon cancer cells and splenocytes in the formation of liver metastases. (2006) (119)
Expression of the biochemical defect of methionine dependence in fresh patient tumors in primary histoculture. (1993) (116)
Induction of cancer metastasis by cyclophosphamide pretreatment of host mice: an opposite effect of chemotherapy. (2008) (116)
Human hair follicle pluripotent stem (hfPS) cells promote regeneration of peripheral‐nerve injury: An advantageous alternative to ES and iPS cells (2009) (116)
Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice. (2001) (112)
Reduced availability of endogenously synthesized methionine for S-adenosylmethionine formation in methionine-dependent cancer cells. (1982) (112)
Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model (2016) (112)
Site-specific chemosensitivity of human small-cell lung carcinoma growing orthotopically compared to subcutaneously in SCID mice: the importance of orthotopic models to obtain relevant drug evaluation data. (1993) (112)
Efficacy of Salmonella typhimurium A1‐R Versus Chemotherapy on a Pancreatic Cancer Patient‐Derived Orthotopic Xenograft (PDOX) (2014) (110)
Establishment of a Patient-Derived Orthotopic Xenograft (PDOX) Model of HER-2-Positive Cervical Cancer Expressing the Clinical Metastatic Pattern (2015) (110)
Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical implications. (2003) (110)
Enhanced in vitro selective toxicity of chemotherapeutic agents for human cancer cells based on a metabolic defect. (1986) (109)
Efficacy of recombinant methioninase in combination with cisplatin on human colon tumors in nude mice. (1999) (108)
A novel "patient-like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice. (1993) (108)
Elevated overall rates of transmethylation in cell lines from diverse human tumors (1984) (107)
A transgenic red fluorescent protein‐expressing nude mouse for color‐coded imaging of the tumor microenvironment (2009) (107)
Real-time imaging of tumor-cell shedding and trafficking in lymphatic channels. (2007) (107)
Liver colonization competence governs colon cancer metastasis. (1995) (106)
Depth-targeted efficient gene delivery and expression in the skin by pulsed electric fields: an approach to gene therapy of skin aging and other diseases. (1996) (104)
Altered methionine metabolism and transmethylation in cancer. (1985) (104)
Extent of DNA methylation in human tumor cells. (1983) (103)
PEGylation Confers Greatly Extended Half-Life and Attenuated Immunogenicity to Recombinant Methioninase in Primates (2004) (102)
The bulge area is the major hair follicle source of nestin-expressing pluripotent stem cells which can repair the spinal cord compared to the dermal papilla (2011) (101)
KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer. (2012) (101)
Genistein inhibits the growth of human‐patient BPH and prostate cancer in histoculture (1998) (101)
Vessel destruction by tumor-targeting Salmonella typhimurium A1-R is enhanced by high tumor vascularity (2010) (101)
Genetically fluorescent melanoma bone and organ metastasis models. (1999) (100)
Imaging of Primary and Metastatic Pancreatic Cancer Using a Fluorophore-Conjugated Anti-CA19-9 Antibody for Surgical Navigation (2008) (99)
Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression (2010) (99)
Tumor-targeting Salmonella typhimurium A1-R decoys quiescent cancer cells to cycle as visualized by FUCCI imaging and become sensitive to chemotherapy (2014) (99)
Targeting the lymphotoxin-beta receptor with agonist antibodies as a potential cancer therapy. (2006) (99)
The Pluripotency of Hair Follicle Stem Cells (2006) (96)
Knockdown of the β1 integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis (2011) (96)
The challenges posed by cancer heterogeneity (2012) (96)
Orthotopic is orthodox: Why are orthotopic‐transplant metastatic models different from all other models? (1994) (96)
White paper on microbial anti-cancer therapy and prevention (2018) (95)
Viable circulating metastatic cells produced in orthotopic but not ectopic prostate cancer models. (2003) (95)
Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model (2016) (95)
High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model (2016) (93)
Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers. (2010) (91)
Metastatic Recurrence in a Pancreatic Cancer Patient Derived Orthotopic Xenograft (PDOX) Nude Mouse Model Is Inhibited by Neoadjuvant Chemotherapy in Combination with Fluorescence-Guided Surgery with an Anti-CA 19-9-Conjugated Fluorophore (2014) (90)
Neddylation Inhibition Activates the Extrinsic Apoptosis Pathway through ATF4–CHOP–DR5 Axis in Human Esophageal Cancer Cells (2016) (89)
Spatial–temporal imaging of bacterial infection and antibiotic response in intact animals (2001) (88)
Orthotopic growth and metastasis of human prostate carcinoma in nude mice after transplantation of histologically intact tissue. (1992) (88)
Low-dose metronomic cyclophosphamide combined with vascular disrupting therapy induces potent antitumor activity in preclinical human tumor xenograft models (2009) (86)
High in vitro‐in vivo correlation of drug response using sponge‐gel‐supported three‐dimensional histoculture and the MTT end point (1992) (86)
Methioninase cancer gene therapy with selenomethionine as suicide prodrug substrate. (2001) (85)
Determination of clonality of metastasis by cell-specific color-coded fluorescent-protein imaging. (2003) (85)
Inhibition and eradication of human glioma with tumor-targeting Salmonella typhimurium in an orthotopic nude-mouse model (2012) (85)
Hair follicle-derived blood vessels vascularize tumors in skin and are inhibited by Doxorubicin. (2005) (85)
Hair shaft elongation, follicle growth, and spontaneous regression in long-term, gelatin sponge-supported histoculture of human scalp skin. (1992) (84)
Tumor-Targeting Salmonella typhimurium A1-R Arrests a Chemo-Resistant Patient Soft-Tissue Sarcoma in Nude Mice (2015) (83)
Salmonella promoters preferentially activated inside tumors. (2008) (83)
Selective methioninase-induced trap of cancer cells in S/G2 phase visualized by FUCCI imaging confers chemosensitivity (2014) (82)
Bacterial Therapy of Cancer: Promises, Limitations, and Insights for Future Directions (2018) (82)
Topical liposome targeting of dyes, melanins, genes, and proteins selectively to hair follicles. (1998) (81)
Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic xenograft (PDOX) model (2016) (81)
In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation. (2003) (81)
Comparison of efficacy of Salmonella typhimurium A1-R and chemotherapy on stem-like and non-stem human pancreatic cancer cells (2013) (81)
Visualization of the metastatic process by green fluorescent protein expression. (1997) (80)
Reduced free‐methionine in methionine‐dependent SV40‐transformed human fibroblasts synthesizing apparently normal amounts of methionine (1983) (79)
Governing step of metastasis visualized in vitro. (1997) (79)
Role of the tumor microenvironment in pancreatic cancer (2019) (79)
Fluorescence-guided Surgery with a Fluorophore-conjugated Antibody to Carcinoembryonic Antigen (CEA), that Highlights the Tumor, Improves Surgical Resection and Increases Survival in Orthotopic Mouse Models of Human Pancreatic Cancer (2014) (79)
Efficacy of Tumor-Targeting Salmonella A1-R on a Melanoma Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Model (2016) (78)
Broad selective efficacy of recombinant methioninase and polyethylene glycol-modified recombinant methioninase on cancer cells In Vitro. (2010) (78)
Selective efficacy of zoledronic acid on metastasis in a patient‐derived orthotopic xenograph (PDOX) nude‐mouse model of human pancreatic cancer (2015) (77)
Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model (2017) (77)
Visualization of GFP-expressing tumors and metastasis in vivo. (2001) (76)
HB-EGF and PDGF mediate reciprocal interactions of carcinoma cells with cancer-associated fibroblasts to support progression of uterine cervical cancers. (2011) (75)
Polyethylene glycol conjugation of recombinant methioninase for cancer therapy. (1998) (75)
Reversion to methionine independence in simian virus 40-transformed human and malignant rat fibroblasts is associated with altered ploidy and altered properties of transformation. (1979) (75)
Extensive multi‐organ metastasis following orthotopic onplantation of histologically‐intact human bladder carcinoma tissue in nude mice (1991) (74)
Tumor-selective, adenoviral-mediated GFP genetic labeling of human cancer in the live mouse reports future recurrence after resection (2011) (74)
Chronologically-specific metastatic targeting of human pancreatic tumors in orthotopic models (2004) (73)
Dual-color imaging of nuclear-cytoplasmic dynamics, viability, and proliferation of cancer cells in the portal vein area. (2006) (73)
Glowing Tumors Make for Better Detection and Resection (2011) (73)
Follicular penetration and targeting. (2005) (73)
Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model (2016) (72)
On the role of classical and novel forms of vitamin D in melanoma progression and management (2017) (72)
Structure of the antitumour enzyme L-methionine gamma-lyase from Pseudomonas putida at 1.8 A resolution. (2007) (71)
An orthotopic mouse model of remetastasis of human colon cancer liver metastasis. (2000) (71)
Hand-held high-resolution fluorescence imaging system for fluorescence-guided surgery of patient and cell-line pancreatic tumors growing orthotopically in nude mice. (2014) (71)
Human tumors are methionine dependent in vivo. (1995) (70)
Metastatic patterns of lung cancer visualized live and in process by green fluorescence protein expression (1997) (70)
Patient-derived orthotopic xenograft (PDOX) nude mouse model of soft-tissue sarcoma more closely mimics the patient behavior in contrast to the subcutaneous ectopic model. (2015) (70)
Application of GFP imaging in cancer (2014) (70)
Multi‐color palette of fluorescent proteins for imaging the tumor microenvironment of orthotopic tumorgraft mouse models of clinical pancreatic cancer specimens (2012) (69)
Human and mouse hair follicles contain both multipotent and monopotent stem cells (2009) (69)
Anticancer efficacy of methioninase in vivo. (1996) (69)
Surgical orthotopic implantation allows high lung and lymph node metastatic expression of human prostate carcinoma cell line PC‐3 in nude mice (1998) (68)
Facile whole-body imaging of internal fluorescent tumors in mice with an LED flashlight. (2005) (68)
Invading cancer cells are predominantly in G0/G1 resulting in chemoresistance demonstrated by real-time FUCCI imaging (2014) (67)
Augmentation of rat alveolar macrophage migration by surfactant protein. (2015) (67)
Antioxidants and the prevention of coronary heart disease. (1995) (66)
Fluorescence-guided surgery allows for more complete resection of pancreatic cancer, resulting in longer disease-free survival compared with standard surgery in orthotopic mouse models. (2012) (65)
Direct evidence that PTHrP expression promotes prostate cancer progression in bone. (2005) (65)
Selective metastatic tumor labeling with green fluorescent protein and killing by systemic administration of telomerase-dependent adenoviruses (2009) (65)
Antigen-Specific Bacterial Vaccine Combined with Anti-PD-L1 Rescues Dysfunctional Endogenous T Cells to Reject Long-Established Cancer (2013) (64)
Imaging cancer dynamics in vivo at the tumor and cellular level with fluorescent proteins (2008) (64)
Sponge-gel-supported histoculture drug-response assay for head and neck cancer. Correlations with clinical response to cisplatin. (1994) (64)
Mutant PIK3CA-bearing colon cancer cells display increased metastasis in an orthotopic model. (2007) (64)
Pharmacokinetics, Methionine Depletion, and Antigenicity of Recombinant Methioninase in Primates (2004) (64)
Suppression of tumor angiogenesis by targeting the protein neddylation pathway (2014) (63)
Serum methionine depletion without side effects by methioninase in metastatic breast cancer patients. (1996) (63)
Recombinant methioninase infusion reduces the biochemical endpoint of serum methionine with minimal toxicity in high-stage cancer patients. (1997) (63)
The hair follicle as a gene therapy target (2000) (62)
A highly metastatic Lewis lung carcinoma orthotopic green fluorescent protein model (2004) (62)
Reversion to methionine independence by malignant rat and SV40-transformed human fibroblasts. (1978) (62)
Development of a high metastatic orthotopic model of human renal cell carcinoma in nude mice: benefits of fragment implantation compared to cell-suspension injection (1999) (62)
Orthotopic Transplant Mouse Models with Green Fluorescent Protein-expressing Cancer Cells to Visualize Metastasis and Angiogenesis (1998) (61)
Correlation of histology and drug response of human tumors grown in native-state three-dimensional histoculture and in nude mice. (1991) (61)
Non-invasive fluorescent-protein imaging of orthotopic pancreatic-cancer-patient tumorgraft progression in nude mice. (2012) (61)
UV light killing efficacy of fluorescent protein‐expressing cancer cells in vitro and in vivo (2010) (60)
Marker expression in circulating cancer cells of pancreatic cancer patients. (2011) (60)
Spatial–temporal FUCCI imaging of each cell in a tumor demonstrates locational dependence of cell cycle dynamics and chemoresponsiveness (2014) (60)
Efficacy of camptothecin analog DX-8951f (Exatecan Mesylate) on human pancreatic cancer in an orthotopic metastatic model. (2003) (59)
Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model (2017) (59)
Tumor-targeting Salmonella typhimurium A1-R arrests growth of breast-cancer brain metastasis (2014) (59)
Synergistic Inhibitory Effect of Traditional Chinese Medicine Astragaloside IV and Curcumin on Tumor Growth and Angiogenesis in an Orthotopic Nude-Mouse Model of Human Hepatocellular Carcinoma. (2017) (59)
A Genetically Engineered Oncolytic Adenovirus Decoys and Lethally Traps Quiescent Cancer Stem–like Cells in S/G2/M Phases (2013) (59)
Advances in cellular, subcellular, and nanoscale imaging in vitro and in vivo (2010) (59)
Modifiable risk factors for incident heart failure in the coronary artery surgery study. (1994) (58)
A general native-state method for determination of proliferation capacity of human normal and tumor tissues in vitro. (1989) (58)
Tumor-specific fluorescence antibody imaging enables accurate staging laparoscopy in an orthotopic model of pancreatic cancer. (2011) (58)
Topical liposome delivery of molecules to hair follicles in mice. (1997) (57)
Tumor‐Targeting Salmonella typhimurium A1‐R Sensitizes Melanoma With a BRAF‐V600E Mutation to Vemurafenib in a Patient‐Derived Orthotopic Xenograft (PDOX) Nude Mouse Model (2017) (57)
Serum and lavage lactate dehydrogenase isoenzymes in pulmonary alveolar proteinosis. (1991) (57)
The potential of nestin-expressing hair follicle stem cells in regenerative medicine (2007) (57)
Fluorescence-guided surgery of human colon cancer increases complete resection resulting in cures in an orthotopic nude mouse model. (2013) (57)
Human Breast Cancer Cell Lines Co-Express Neuronal, Epithelial, and Melanocytic Differentiation Markers In Vitro and In Vivo (2010) (57)
Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRβ/B-RAF (2010) (56)
Cancer-cell killing by engineered Salmonella imaged by multiphoton tomography in live mice. (2012) (55)
Skin toxicity determined in vitro by three-dimensional, native-state histoculture. (1991) (55)
Efficacy of Tumor‐Targeting Salmonella Typhimurium A1‐R on Nude Mouse Models of Metastatic and Disseminated Human Ovarian Cancer (2014) (55)
Determination of the optimal route of administration of Salmonella typhimurium A1-R to target breast cancer in nude mice. (2012) (55)
In vivo tumor delivery of the green fluorescent protein gene to report future occurrence of metastasis (2000) (54)
Metronomic Gemcitabine in Combination with Sunitinib Inhibits Multisite Metastasis and Increases Survival in an Orthotopic Model of Pancreatic Cancer (2010) (54)
A patient-like orthotopic implantation nude mouse model of highly metastatic human ovarian cancer (1998) (54)
Intraperitoneal administration of tumor-targeting Salmonella typhimurium A1-R inhibits disseminated human ovarian cancer and extends survival in nude mice (2015) (54)
Color-coding cancer and stromal cells with genetic reporters in a patient-derived orthotopic xenograft (PDOX) model of pancreatic cancer enhances fluorescence-guided surgery (2015) (54)
Tumor-Targeting Salmonella typhimurium A1-R in Combination with Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived Mouse Models (2015) (54)
Real‐time imaging of single cancer‐cell dynamics of lung metastasis (2009) (53)
Tumor-specific cell-cycle decoy by Salmonella typhimurium A1-R combined with tumor-selective cell-cycle trap by methioninase overcome tumor intrinsic chemoresistance as visualized by FUCCI imaging (2016) (53)
Recombinant methioninase in combination with doxorubicin (DOX) overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma. (2018) (53)
Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug (2016) (53)
Near Infra-Red Photoimmunotherapy with Anti-CEA-IR700 Results in Extensive Tumor Lysis and a Significant Decrease in Tumor Burden in Orthotopic Mouse Models of Pancreatic Cancer (2015) (53)
Imageable fluorescent metastasis resulting in transgenic GFP mice orthotopically implanted with human-patient primary pancreatic cancer specimens. (2012) (53)
Orthotopic metastatic (MetaMouse) models for discovery and development of novel chemotherapy. (2005) (53)
Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer. (2018) (53)
An LED light source and novel fluorophore combinations improve fluorescence laparoscopic detection of metastatic pancreatic cancer in orthotopic mouse models. (2012) (53)
Optically imageable metastatic model of human breast cancer (2004) (53)
Intra-arterial administration of tumor-targeting Salmonella typhimurium A1-R regresses a cisplatin-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model (2017) (53)
Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation. (2017) (53)
Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: decoy, trap and kill chemotherapy moves toward the clinic (2018) (52)
Real‐time whole‐body imaging of an orthotopic metastatic prostate cancer model expressing red fluorescent protein (2005) (52)
Fluorescent LYVE-1 antibody to image dynamically lymphatic trafficking of cancer cells in vivo. (2009) (52)
Ovarian Tumor Attachment, Invasion, and Vascularization Reflect Unique Microenvironments in the Peritoneum: Insights from Xenograft and Mathematical Models (2013) (51)
An imageable highly metastatic orthotopic red fluorescent protein model of pancreatic cancer (2004) (51)
The role of hair follicle nestin‐expressing stem cells during whisker sensory‐nerve growth in long‐term 3D culture (2013) (51)
Improvement in alveolar macrophage migration after therapeutic whole lung lavage in pulmonary alveolar proteinosis. (1989) (50)
Development of the transgenic cyan fluorescent protein (CFP)‐expressing nude mouse for “Technicolor” cancer imaging (2009) (50)
High-level expression and bulk crystallization of recombinant l-methionine γ-lyase, an anticancer agent (2006) (49)
High-throughput screening for salmonella avirulent mutants that retain targeting of solid tumors. (2010) (49)
From hair to heart: nestin-expressing hair-follicle-associated pluripotent (HAP) stem cells differentiate to beating cardiac muscle cells (2015) (49)
Ratiometric Activatable Cell-Penetrating Peptides Label Pancreatic Cancer, Enabling Fluorescence-Guided Surgery, Which Reduces Metastases and Recurrence in Orthotopic Mouse Models (2014) (49)
Real-Time In Vivo Green Fluorescent Protein Imaging of a Murine Leishmaniasis Model as a New Tool for Leishmania Vaccine and Drug Discovery (2008) (48)
Hypomethylation of HeLa cell DNA and the absence of 5-methylcytosine in SV40 and adenovirus (type 2) DNA: analysis by HPLC. (1982) (48)
Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy (2016) (48)
Tumor-seeking Salmonella amino acid auxotrophs. (2011) (48)
Exploiting methionine restriction for cancer treatment. (2018) (47)
An ultra-metastatic model of human colon cancer in nude mice (1999) (47)
Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma (2015) (47)
Magnetic resonance and fluorescence imaging of doxorubicin-loaded nanoparticles using a novel in vivo model. (2010) (47)
Promotion of tumor-associated macrophages infiltration by elevated neddylation pathway via NF-κB-CCL2 signaling in lung cancer (2019) (47)
Methionine starvation modulates the efficacy of cisplatin on human breast cancer in nude mice. (1996) (47)
Advantages of multi-color fluorescent proteins for whole-body and in vivo cellular imaging. (2005) (47)
Anticoagulant drugs increase natural killer cell activity in lung cancer. (2005) (47)
High correlation of whole-body red fluorescent protein imaging and magnetic resonance imaging on an orthotopic model of pancreatic cancer. (2005) (47)
Dual-Color-Coded Imaging of Viable Circulating Prostate Carcinoma Cells Reveals Genetic Exchange between Tumor Cells In Vivo, Contributing to Highly Metastatic Phenotypes (2006) (47)
Protein-tyrosine Pseudokinase 7 (PTK7) Directs Cancer Cell Motility and Metastasis* (2014) (46)
Involvement of CXCR4 Chemokine Receptor in Metastastic HER2-Positive Esophageal Cancer (2012) (46)
Advantages of fluorescence-guided laparoscopic surgery of pancreatic cancer labeled with fluorescent anti-carcinoembryonic antigen antibodies in an orthotopic mouse model. (2014) (46)
In vitro/in vivo biorecognition of lectin-immobilized fluorescent nanospheres for human colorectal cancer cells. (2009) (46)
Patient-derived orthotopic xenograft (PDOX) mouse model of adult rhabdomyosarcoma invades and recurs after resection in contrast to the subcutaneous ectopic model (2017) (46)
Host organ specifically determines cancer progression. (1995) (46)
Complementarity of ultrasound and fluorescence imaging in an orthotopic mouse model of pancreatic cancer (2009) (46)
A patient-like metastasizing model of human lung adenocarcinoma constructed via thoracotomy in nude mice. (1992) (45)
Time-Course Imaging of Therapeutic Functional Tumor Vascular Normalization by Antiangiogenic Agents (2011) (45)
Oral Recombinant Methioninase Combined with Caffeine and Doxorubicin Induced Regression of a Doxorubicin-resistant Synovial Sarcoma in a PDOX Mouse Model (2018) (45)
to the Outcome of Cancer Therapy (2002) (45)
A new patient-like metastatic model of human small-cell lung cancer constructed orthotopically with intact tissue via thoracotomy in nude mice. (1992) (45)
VEGF receptor antisense therapy inhibits angiogenesis and peritoneal dissemination of human gastric cancer in nude mice (2002) (45)
Nestin‐positive hair follicle pluripotent stem cells can promote regeneration of impinged peripheral nerve injury (2012) (45)
Chemotherapy targets the hair-follicle vascular network but not the stem cells. (2007) (44)
Tumor Cells Genetically Labeled with GFP in the Nucleus and RFP in the Cytoplasm for Imaging Cellular Dynamics (2006) (44)
Minimal antiproliferative effect of recombinant müllerian inhibiting substance on gynecological tumor cell lines and tumor explants. (1989) (44)
A better fluorescent protein for whole-body imaging. (2008) (43)
Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation (2017) (43)
Efficacy against lung metastasis with a tumor-targeting mutant of Salmonella typhimurium in immunocompetent mice (2012) (43)
Chemosensitivity of breast cancer lymph node metastasis compared to the primary tumor from individual patients tested in the histoculture drug response assay. (2000) (43)
In vitro assays for chemotherapy sensitivity. (1993) (43)
Bax-induction gene therapy of pancreatic cancer. (2002) (42)
Imaging tumor angiogenesis with fluorescent proteins. (2004) (42)
Total-homocysteine enzymatic assay. (2000) (42)
Use of histoculture and green fluorescent protein to visualize tumor cell host interaction (1997) (42)
Salmonella typhimurium A1-R targeting of a chemotherapy-resistant BRAF-V600E melanoma in a patient-derived orthotopic xenograft (PDOX) model is enhanced in combination with either vemurafenib or temozolomide (2017) (42)
Cisplatin sensitivity of ovarian cancer in the histoculture drug response assay correlates to clinical response to combination chemotherapy with cisplatin, doxorubicin and cyclophosphamide. (2000) (41)
The role of the intravascular microenvironment in spontaneous metastasis development (2010) (41)
Gene Therapy of Pancreatic Cancer With Green Fluorescent Protein and Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Fusion Gene Expression Driven by a Human Telomerase Reverse Transcriptase Promoter (2003) (41)
High‐malignancy orthotopic nude mouse model of human prostate cancer LNCaP (1999) (41)
Oncogenic miRNAs Identified in Tear Exosomes From Metastatic Breast Cancer Patients (2020) (41)
Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models (2017) (41)
Partial purification of proteins from pea leaflets that inhibit Ascochyta pisi endopolygalacturonase (1982) (41)
Experimental Curative Fluorescence-guided Surgery of Highly Invasive Glioblastoma Multiforme Selectively Labeled With a Killer-reporter Adenovirus. (2015) (41)
Selective antimetastatic activity of cytosine analog CS-682 in a red fluorescent protein orthotopic model of pancreatic cancer. (2003) (40)
Multiphoton tomography visualizes collagen fibers in the tumor microenvironment that maintain cancer‐cell anchorage and shape (2013) (40)
Nestin-Expressing Stem Cells Promote Nerve Growth in Long-Term 3-Dimensional Gelfoam®-Supported Histoculture (2013) (40)
Improved Resection and Outcome of Colon-Cancer Liver Metastasis with Fluorescence-Guided Surgery Using In Situ GFP Labeling with a Telomerase-Dependent Adenovirus in an Orthotopic Mouse Model (2016) (40)
The advantages of hair follicle pluripotent stem cells over embryonic stem cells and induced pluripotent stem cells for regenerative medicine. (2010) (39)
Methioninase gene therapy of human cancer cells is synergistic with recombinant methioninase treatment. (2000) (39)
Imaging the efficacy of UVC irradiation on superficial brain tumors and metastasis in live mice at the subcellular level (2013) (39)
Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer (2015) (39)
In Vitro Culture and Characterization of Human Lung Cancer Circulating Tumor Cells Isolated by Size Exclusion from an Orthotopic Nude-Mouse Model Expressing Fluorescent Protein (2014) (39)
The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago (2017) (39)
Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R (2014) (39)
Dual-color imaging of nascent blood vessels vascularizing pancreatic cancer in an orthotopic model demonstrates antiangiogenesis efficacy of gemcitabine. (2006) (39)
High Efficacy of Pazopanib on an Undifferentiated Spindle‐Cell Sarcoma Resistant to First‐Line Therapy Is Identified With a Patient‐Derived Orthotopic Xenograft (PDOX) Nude Mouse Model (2017) (39)
Whole-body imaging of bacterial infection and antibiotic response (2006) (38)
Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention (2018) (38)
Imaging the recruitment of cancer‐associated fibroblasts by liver‐metastatic colon cancer (2011) (38)
Methionine-depletion modulates the efficacy of 5-fluorouracil in human gastric cancer in nude mice. (1997) (38)
In vivo imaging with fluorescent proteins: the new cell biology. (2004) (38)
Current status and future perspectives of fluorescence-guided surgery for cancer (2016) (38)
Efficacy of Recombinant Methioninase (rMETase) on Recalcitrant Cancer Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models: A Review (2019) (38)
Collective cancer invasion forms an integrin-dependent radioresistant niche (2019) (38)
A clinical nude mouse metastatic model for highly malignant human pancreatic cancer. (1996) (38)
In Vivo Fluorescence Imaging Reveals the Promotion of Mammary Tumorigenesis by Mesenchymal Stromal Cells (2013) (38)
Multipotent nestin‐expressing hair follicle stem cells (2009) (38)
Labeling the Stroma of a Patient‐Derived Orthotopic Xenograft (PDOX) Mouse Model of Undifferentiated Pleomorphic Soft‐Tissue Sarcoma With Red Fluorescent Protein for Rapid Non‐Invasive Imaging for Drug Screening (2017) (37)
MEK inhibitors cobimetinib and trametinib, regressed a gemcitabine-resistant pancreatic-cancer patient-derived orthotopic xenograft (PDOX) (2017) (37)
The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing’s sarcoma with a FUS-ERG fusion and CDKN2A deletion: Direction for third-line patient therapy (2017) (37)
Methods for the development of tumor-targeting bacteria (2014) (37)
5-FU-induced apoptosis correlates with efficacy against human gastric and colon cancer xenografts in nude mice. (1997) (37)
Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells. (2020) (37)
Fluorescence-guided surgery, but not bright-light surgery, prevents local recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) model resistant to neoadjuvant chemotherapy (NAC). (2015) (37)
Relevance of Vitamin D in Melanoma Development, Progression and Therapy (2020) (37)
Human RT‐4 bladder carcinoma is highly metastatic in nude mice and comparable ras‐H‐transformed RT‐4 when orthotopically onplanted as histologically intact tisuee (1992) (37)
A patient-derived orthotopic xenograft (PDOX) mouse model of a cisplatinum-resistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications for precision oncology. (2017) (37)
Effective Therapeutic Targeting of the Overexpressed HER-2 Receptor in a Highly Metastatic Orthotopic Model of Esophageal Carcinoma (2010) (37)
Occurrence and specificity of an endopolygalacturonase inhibitor in Pisum sativum (1984) (36)
Complementary use of fluorescence and magnetic resonance imaging of metastatic esophageal cancer in a novel orthotopic mouse model (2010) (36)
Depletion of serum methionine by methioninase in mice. (1993) (36)
Myc is a prognostic biomarker and potential therapeutic target in osteosarcoma (2020) (36)
Unbalanced transmethylation and the perturbation of the differentiated state leading to cancer (1990) (36)
Direct transplantation of uncultured hair‐follicle pluripotent stem (hfPS) cells promotes the recovery of peripheral nerve injury (2010) (36)
In vivo cell biology of cancer cells visualized with fluorescent proteins. (2005) (35)
In vivo gene transfer between interacting human osteosarcoma cell lines is associated with acquisition of enhanced metastatic potential (2009) (35)
In Vivo Fluorescence Imaging of Gastrointestinal Stromal Tumors Using Fluorophore-Conjugated Anti-KIT Antibody (2013) (35)
Parathyroid Hormone Related-Protein Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer (2014) (35)
A patient-like human malignant pleural mesothelioma nude-mouse model. (1996) (35)
Circulating human prostate cancer cells from an orthotopic mouse model rapidly captured by immunomagnetic beads and imaged by GFP expression. (2011) (35)
Antimetastatic efficacy of adjuvant gemcitabine in a pancreatic cancer orthotopic model (2004) (35)
Tumor imaging with multicolor fluorescent protein expression (2011) (35)
Tumor-targeting Salmonella typhimurium A1-R prevents experimental human breast cancer bone metastasis in nude mice (2014) (35)
In vivo transdermal delivery of large molecules by pressure-mediated electroincorporation and electroporation: a novel method for drug and gene delivery☆ (1997) (35)
Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone (2018) (35)
The Bisphosphonate Olpadronate Inhibits Skeletal Prostate Cancer Progression in a Green Fluorescent Protein Nude Mouse Model (2006) (35)
Nestin-Expressing Hair Follicle-Accessible Pluripotent Stem Cells for Nerve and Spinal Cord Repair (2015) (34)
The Preparation of Endotoxin-Free L-Methionine-α-deamino-γ-mercaptomethane-lyase (L-Methioninase) from Pseudomonas putida (1993) (34)
Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore (2018) (34)
Multipotent nestin-expressing stem cells capable of forming neurons are located in the upper, middle and lower part of the vibrissa hair follicle (2012) (34)
Patient-Derived Mouse Models of Cancer (2017) (34)
An Imageable Metastatic Treatment Model of Nasopharyngeal Carcinoma (2007) (34)
Fluorescence laparoscopy imaging of pancreatic tumor progression in an orthotopic mouse model (2010) (34)
Watching stem cells in the skin of living mice noninvasively (2011) (34)
Solid tumors provide niche-specific conditions that lead to preferential growth of Salmonella (2016) (33)
Comparison of a chimeric anti-carcinoembryonic antigen antibody conjugated with visible or near-infrared fluorescent dyes for imaging pancreatic cancer in orthotopic nude mouse models (2013) (33)
Stromal-cell and cancer-cell exosomes leading the metastatic exodus for the promised niche (2013) (33)
Comparison of the selective targeting efficacy of Salmonella typhimurium A1-R and VNP20009 on the Lewis lung carcinoma in nude mice (2015) (33)
Conversion of highly malignant colon cancer from an aggressive to a controlled disease by oral administration of a metalloproteinase inhibitor (1997) (33)
Acquisition of multidrug resistance in recurrent breast cancer demonstrated by the histoculture drug response assay. (2001) (33)
Magnetic resonance and fluorescence-protein imaging of the anti-angiogenic and anti-tumor efficacy of selenium in an orthotopic model of human colon cancer. (2011) (33)
Effective fluorescence‐guided surgery of liver metastasis using a fluorescent anti‐CEA antibody (2016) (33)
Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model. (2019) (33)
Development of a green fluorescent protein metastatic-cancer chick-embryo drug-screen model (2004) (33)
The wayward methyl group and the cascade to cancer (2017) (32)
Color-coded fluorescent protein imaging of angiogenesis: the AngioMouse models. (2008) (32)
Survival Efficacy of Adjuvant Cytosine-Analogue CS-682 in a Fluorescent Orthotopic Model of Human Pancreatic Cancer (2004) (32)
Cancer cells mimic in vivo spatial-temporal cell-cycle phase distribution and chemosensitivity in 3-dimensional Gelfoam® histoculture but not 2-dimensional culture as visualized with real-time FUCCI imaging (2015) (32)
Liposome targeting of high molecular weight DNA to the hair follicles of histocultured skin: A model for gene therapy of the hair growth processes (1993) (32)
Monitoring of skeletal progression of prostate cancer by GFP imaging, X‐ray, and serum OPG and PTHrP (2005) (32)
Methioninase gene therapy with selenomethionine induces apoptosis in bcl-2-overproducing lung cancer cells (2003) (32)
Real-time GFP imaging of spontaneous HT-1080 fibrosarcoma lung metastases (2004) (32)
Electroporation therapy of human larynx tumors HEp-2 implanted in nude mice. (1998) (32)
Precise navigation surgery of tumours in the lung in mouse models enabled by in situ fluorescence labelling with a killer-reporter adenovirus (2015) (31)
3‐Dimensional Tissue Is Formed From Cancer Cells In Vitro on Gelfoam®, But Not on MatrigelTM (2014) (31)
Green fluorescent protein imaging of tumor cells in mice. (2002) (31)
Cancer biology for individualized therapy: correlation of growth fraction index in native-state histoculture with tumor grade and stage. (1990) (31)
Oral dosing of Recombinant Methioninase Is Associated With a 70% Drop in PSA in a Patient With Bone-metastatic Prostate Cancer and 50% Reduction in Circulating Methionine in a High-stage Ovarian Cancer Patient (2020) (31)
Is DNA methylation the new guardian of the genome? (2017) (31)
Extensive liver metastasis from human colon cancer in nude and scid mice after orthotopic onplantation of histologically-intact human colon carcinoma tissue. (1992) (31)
Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression (2002) (31)
In vivo imaging of metastatic cancer with fluorescent proteins (2002) (31)
Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models (2018) (31)
Real-time confocal imaging of trafficking of nestin-expressing multipotent stem cells in mouse whiskers in long-term 3-D histoculture (2012) (31)
Characterization of nerve conduits seeded with neurons and Schwann cells derived from hair follicle neural crest stem cells. (2011) (31)
Real-time imaging of individual fluorescent-protein color-coded metastatic colonies in vivo (2004) (31)
Imaging the Interaction of Pancreatic Cancer and Stellate Cells in the Tumor Microenvironment during Metastasis. (2015) (31)
The distinction of small cell and non-small cell lung cancer by growth in native-state histoculture. (1990) (31)
Electroporation enhances therapeutic efficacy of anticancer drugs: treatment of human pancreatic tumor in animal model. (1998) (30)
Efficacy of the Chinese traditional medicinal herb Celastrus orbiculatus Thunb on human hepatocellular carcinoma in an orthothopic fluorescent nude mouse model. (2012) (30)
Early resection of primary orthotopically-growing human colon tumor in nude mouse prevents liver metastasis: further evidence for patient-like hematogenous metastatic route. (1993) (30)
Tumor-educated macrophages promote tumor growth and peritoneal metastasis in an orthotopic nude mouse model of human pancreatic cancer. (2012) (30)
Patient-Derived Orthotopic Xenograft (PDOX) Models of Melanoma † (2017) (30)
Photoimmunotherapy lowers recurrence after pancreatic cancer surgery in orthotopic nude mouse models. (2015) (29)
Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer (2018) (29)
Combination of gemcitabine and docetaxel regresses both gastric leiomyosarcoma proliferation and invasion in an imageable patient-derived orthotopic xenograft (iPDOX) model (2017) (29)
Minimal liver resection strongly stimulates the growth of human colon cancer in the liver of nude mice (2004) (29)
Dual-color imaging of nascent angiogenesis and its inhibition in liver metastases of pancreatic cancer. (2006) (29)
A nude mouse model of massive liver and lymph node metastasis of human colon cancer. (2000) (29)
A "patient-like" nude mouse model of parietal pleural human lung adenocarcinoma. (1994) (28)
Homogeneous, nonradioactive, enzymatic assay for plasma pyridoxal 5-phosphate. (2002) (28)
Multi-organ metastatic capability of Chinese hamster ovary cells revealed by green fluorescent protein (GFP) expression (1999) (28)
High lung-metastatic variant of human osteosarcoma cells, selected by passage of lung metastasis in nude mice, is associated with increased expression of α(v)β(3) integrin. (2013) (28)
Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma (2019) (28)
The camptothecin derivative CPT-11 inhibits angiogenesis in a dual-color imageable orthotopic metastatic nude mouse model of human colon cancer. (2007) (28)
High efficiency genetic modification of hair follicles and growing hair shafts (2002) (28)
Imaging the Different Mechanisms of Prostate Cancer Cell-killing by Tumor-targeting Salmonella typhimurium A1-R. (2015) (28)
Fluorescence lifetime microscopy of tumor cell invasion, drug delivery, and cytotoxicity. (2012) (28)
Combination Efficacy of Astragalus membranaceus and Curcuma wenyujin at Different Stages of Tumor Progression in an Imageable Orthotopic Nude Mouse Model of Metastatic Human Ovarian Cancer Expressing Red Fluorescent Protein. (2015) (28)
Color-coded real-time cellular imaging of lung T-lymphocyte accumulation and focus formation in a mouse asthma model. (2010) (28)
Growth of doxorubicin‐resistant undifferentiated spindle‐cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase (2018) (28)
Methionine dependence in cancer cells — A review (1982) (28)
Pioglitazone, an agonist of PPARγ, reverses doxorubicin-resistance in an osteosarcoma patient-derived orthotopic xenograft model by downregulating P-glycoprotein expression. (2019) (28)
Two-photon laser-generated microtracks in 3D collagen lattices: principles of MMP-dependent and -independent collective cancer cell invasion (2011) (28)
Tumor-targeting amino acid auxotrophic Salmonella typhimurium (2009) (27)
Surgically-Induced Multi-organ Metastasis in an Orthotopic Syngeneic Imageable Model of 4T1 Murine Breast Cancer. (2015) (27)
Neoadjuvant chemoradiotherapy of pancreatic cancer induces a favorable immunogenic tumor microenvironment associated with increased major histocompatibility complex class I‐related chain A/B expression (2017) (27)
The combination of oral-recombinant methioninase and azacitidine arrests a chemotherapy-resistant osteosarcoma patient-derived orthotopic xenograft mouse model (2019) (27)
Efficacy of oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil on primary colon cancer in a patient-derived orthotopic xenograft mouse model. (2019) (27)
Isoproterenol directs hair follicle-associated pluripotent (HAP) stem cells to differentiate in vitro to cardiac muscle cells which can be induced to form beating heart-muscle tissue sheets (2016) (27)
Fluorescence-Guided Surgery in Combination with UVC Irradiation Cures Metastatic Human Pancreatic Cancer in Orthotopic Mouse Models (2014) (27)
Fluorescence‐guided surgery improves outcome in an orthotopic osteosarcoma nude‐mouse model (2014) (27)
Visualization of nascent tumor angiogenesis in lung and liver metastasis by differential dual-color fluorescence imaging in nestin-linked-GFP mice (2007) (27)
Physicochemical and pharmacokinetic characterization of highly potent recombinant L-methionine gamma-lyase conjugated with polyethylene glycol as an antitumor agent. (2006) (27)
Fluorescent proteins enhance UVC PDT of cancer cells. (2012) (27)
A rapid HPLC method for the measurement of ultra-low plasma methionine concentrations applicable to methionine depletion therapy. (2005) (27)
A novel alkylating agent, glufosfamide, enhances the activity of gemcitabine in vitro and in vivo. (2007) (27)
Liposomes can specifically target entrapped melanin to hair follicles in histocultured skin (1993) (26)
GFP-fluorescence-guided UVC irradiation inhibits melanoma growth and angiogenesis in nude mice. (2010) (26)
Chemoprevention by Quercetin of Oral Squamous Cell Carcinoma by Suppression of the NF-κB Signaling Pathway in DMBA-treated Hamsters. (2017) (26)
Tumor-targeting Salmonella typhimurium A1-R is a highly effective general therapeutic for undifferentiated soft tissue sarcoma patient-derived orthotopic xenograft nude-mouse models. (2018) (26)
Metabolic targeting with recombinant methioninase combined with palbociclib regresses a doxorubicin-resistant dedifferentiated liposarcoma. (2018) (26)
Effect of verapamil on the expression of EGFR and NM23 in A549 human lung cancer cells. (2009) (26)
Fluorescence-Guided Surgery and Fluorescence Laparoscopy for Gastrointestinal Cancers in Clinically-Relevant Mouse Models (2013) (26)
Correlation of proteolytic activities of organ cultured intact mouse skin with defined hair cycle stages. (1994) (26)
“Patient‐Like” nude mouse metastatic model of advanced human pleural cancer (1994) (26)
Comparison of Efficacy and Toxicity of Traditional Chinese Medicine (TCM) Herbal Mixture LQ and Conventional Chemotherapy on Lung Cancer Metastasis and Survival in Mouse Models (2014) (25)
Cell-cycle fate-monitoring distinguishes individual chemosensitive and chemoresistant cancer cells in drug-treated heterogeneous populations demonstrated by real-time FUCCI imaging (2015) (25)
Circulating Half-Life of PEGylated Recombinant Methioninase Holoenzyme Is Highly Dose Dependent on Cofactor Pyridoxal-5′-Phosphate (2004) (25)
Traditional Chinese Medicine (TCM) Astragalus Membranaceus and Curcuma Wenyujin Promote Vascular Normalization in Tumor-derived Endothelial Cells of Human Hepatocellular Carcinoma (2019) (25)
Parathyroid Hormone-related Protein as a Novel Tumor Marker in Pancreatic Adenocarcinoma (2002) (25)
Product-delivering liposomes specifically target hair follicles in histocultured intact skin (1992) (25)
Polyethylene Glycol (PEG) Linked to Near Infrared (NIR) Dyes Conjugated to Chimeric Anti-Carcinoembryonic Antigen (CEA) Antibody Enhances Imaging of Liver Metastases in a Nude-Mouse Model of Human Colon Cancer (2014) (25)
Paclitaxel nanosuspensions for targeted chemotherapy – nanosuspension preparation, characterization, and use (2014) (25)
Reversible inhibition of IL-8 receptor B mRNA expression and proliferation in non-small cell lung cancer by antisense oligonucleotides. (1996) (25)
Visualization of xenotransplanted human rhabdomyosarcoma after transfection with red fluorescent protein. (2006) (25)
The development of fluorescence guided surgery for pancreatic cancer: from bench to clinic (2018) (25)
Combination therapy of tumor-targeting Salmonella typhimurium A1-R and oral recombinant methioninase regresses a BRAF-V600E-negative melanoma. (2018) (24)
The cyan fluorescent protein nude mouse as a host for multicolor-coded imaging models of primary and metastatic tumor microenvironments. (2012) (24)
Survival efficacy of the combination of the methioninase gene and methioninase in a lung cancer orthotopic model (2000) (24)
Cancer seed and soil can be highly selective: human-patient colon tumor lung metastasis grows in nude mouse lung but not colon or subcutis. (1995) (24)
Cell-cycle-dependent drug-resistant quiescent cancer cells induce tumor angiogenesis after chemotherapy as visualized by real-time FUCCI imaging (2017) (24)
Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis (2017) (24)
Oral Recombinant Methioninase Overcomes Colorectal-cancer Liver Metastasis Resistance to the Combination of 5-Fluorouracil and Oxaliplatinum in a Patient-derived Orthotopic Xenograft Mouse Model (2019) (24)
Measurement of androgen sensitivity in the human prostate in in vitro three‐dimensional histoculture (1992) (24)
Photoimmunotherapy Inhibits Tumor Recurrence After Surgical Resection on a Pancreatic Cancer Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model (2015) (24)
Drug response of head and neck tumors in native-state histoculture. (1991) (24)
THE FORMATION OF VITAMIN D BY CATHODE RAYS (1936) (24)
Nestin‐expressing interfollicular blood vessel network contributes to skin transplant survival and wound healing (2010) (24)
Relationship between home glucose testing and hemoglobin Alc in type II diabetes patients. (1997) (24)
Regulation of methionine adenosyltransferase in normal diploid and simian virus 40-transformed human fibroblasts. (1980) (24)
Color-coded real-time subcellular fluorescence imaging of the interaction between cancer and host cells in live mice. (2012) (24)
Temozolomide combined with irinotecan caused regression in an adult pleomorphic rhabdomyosarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model. (2017) (24)
PPARγ Agonist Pioglitazone in Combination With Cisplatinum Arrests a Chemotherapy-resistant Osteosarcoma PDOX Model (2019) (24)
In vitro photodynamic therapy of childhood rhabdomyosarcoma. (2007) (24)
P-Glycoprotein Overexpression Is Associated With Cisplatin Resistance in Human Osteosarcoma (2019) (24)
Real‐Time GFP Intravital Imaging of the Differences in Cellular and Angiogenic Behavior of Subcutaneous and Orthotopic Nude‐Mouse Models of Human PC‐3 Prostate Cancer (2016) (24)
Blockage of autophagy pathway enhances Salmonella tumor-targeting (2016) (23)
Traditional Chinese Medicine Curcumin Sensitizes Human Colon Cancer to Radiation by Altering the Expression of DNA Repair-related Genes. (2018) (23)
Nanoparticle albumin-bound-paclitaxel: a limited improvement under the current therapeutic paradigm of pancreatic cancer (2015) (23)
Combining Tumor-Selective Bacterial Therapy with Salmonella typhimurium A1-R and Cancer Metabolism Targeting with Oral Recombinant Methioninase Regressed an Ewing’s Sarcoma in a Patient-Derived Orthotopic Xenograft Model (2019) (23)
Upregulation of thrombospondin-1 and angiogenesis in an aggressive human pancreatic cancer cell line selected for high metastasis (2009) (23)
Robo1-specific CAR-NK Immunotherapy Enhances Efficacy of 125I Seed Brachytherapy in an Orthotopic Mouse Model of Human Pancreatic Carcinoma (2019) (23)
Simultaneous color‐coded imaging to distinguish cancer “stem‐like” and non‐stem cells in the same tumor (2010) (23)
Combination Treatment With Sorafenib and Everolimus Regresses a Doxorubicin-resistant Osteosarcoma in a PDOX Mouse Model (2019) (23)
MUC1 Selectively Targets Human Pancreatic Cancer in Orthotopic Nude Mouse Models (2015) (23)
Tumor-Targeting Salmonella typhimurium A1-R: An Overview. (2016) (23)
Cryopreservation of the Hair Follicle Maintains Pluripotency of Nestin-Expressing Hair Follicle-Associated Pluripotent Stem Cells. (2015) (23)
Metastatic human pleural ovarian cancer model constructed by orthotopic implantation of fresh histologically-intact patient carcinoma in nude mice. (1993) (23)
Gene and stem cell therapy of the hair follicle. (2005) (22)
Skin histoculture assay for studying the hair cycle (1992) (22)
Imaging UVC‐induced DNA damage response in models of minimal cancer (2013) (22)
Efficacy of dietary antioxidants combined with a chemotherapeutic agent on human colon cancer progression in a fluorescent orthotopic mouse model. (2009) (22)
Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model (2017) (22)
Long-working-distance fluorescence microscope with high-numerical-aperture objectives for variable-magnification imaging in live mice from macro- to subcellular. (2010) (22)
Hair follicle-associated-pluripotent (HAP) stem cells (2017) (22)
Prostate Cancer Heterogeneous High-Metastatic Multi-Organ-Colonizing Chemo-Resistant Variants Selected by Serial Metastatic Passage in Nude Mice Are Highly Enriched for Multinucleate Giant Cells (2015) (22)
Advantages of patient‐derived orthotopic mouse models and genetic reporters for developing fluorescence‐guided surgery (2018) (22)
Automated enzymatic assay for homocysteine. (2003) (22)
The three-dimensional question: can clinically relevant tumor drug resistance be measuredin vitro? (1994) (22)
Clinical course of human epithelial-type malignant pleural mesothelioma replicated in an orthotopic-transplant nude mouse model. (1996) (21)
Dynamic color‐coded fluorescence imaging of the cell‐cycle phase, mitosis, and apoptosis demonstrates how caffeine modulates cisplatinum efficacy (2013) (21)
Imaging the inhibition by anti‐β1 integrin antibody of lung seeding of single osteosarcoma cells in live mice (2012) (21)
Surgical and Oncological Factors Affecting the Successful Engraftment of Patient-derived Xenografts in Pancreatic Ductal Adenocarcinoma. (2016) (21)
Common bile duct injection as a novel method for establishing red fluorescent protein (RFP)-expressing human pancreatic cancer in nude mice. (2006) (21)
Efficacy of glycogen synthase kinase-3β targeting against osteosarcoma via activation of β-catenin (2016) (21)
Effective Electroporation Therapy of Human Pancreatic Tumors Implanted in Nude Mice. (1997) (21)
A rapid imageable in vivo metastasis assay for circulating tumor cells. (2011) (21)
Submillimeter-resolution fluorescence laparoscopy of pancreatic cancer in a carcinomatosis mouse model visualizes metastases not seen with standard laparoscopy. (2011) (21)
Histocultures and Their Use (2010) (21)
Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models (2020) (21)
The preclinical discovery of bacterial therapy for the treatment of metastatic cancer with unique advantages (2012) (21)
Cytotoxic synergism of methioninase in combination with 5-fluorouracil and folinic acid. (2001) (21)
Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis. (2002) (20)
Lentivirus-based DsRed-2-transfected pancreatic cancer cells for deep in vivo imaging of metastatic disease. (2009) (20)
Dual-color imaging of angiogenesis and its inhibition in bone and soft tissue sarcoma. (2007) (20)
Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model (2018) (20)
Comparison of UVB and UVC Effects on the DNA Damage‐Response Protein 53BP1 in Human Pancreatic Cancer (2014) (20)
Eradication of osteosarcoma by fluorescence‐guided surgery with tumor labeling by a killer‐reporter adenovirus (2016) (20)
Moesin Expression Is Associated with Glioblastoma Cell Proliferation and Invasion. (2017) (20)
Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model. (2020) (20)
Sorafenib and Palbociclib Combination Regresses a Cisplatinum-resistant Osteosarcoma in a PDOX Mouse Model (2019) (20)
A color‐coded orthotopic nude‐mouse treatment model of brain‐metastatic paralyzing spinal cord cancer that induces angiogenesis and neurogenesis (2009) (20)
Methionine depletion modulates the antitumor and antimetastatic efficacy of ethionine. (1996) (20)
Efficacy comparison of traditional Chinese medicine LQ versus gemcitabine in a mouse model of pancreatic cancer (2013) (20)
Cervical Cancer Patient-Derived Orthotopic Xenograft (PDOX) Is Sensitive to Cisplatinum and Resistant to Nab-paclitaxel. (2017) (20)
Near-infrared-conjugated humanized anti-carcinoembryonic antigen antibody targets colon cancer in an orthotopic nude-mouse model. (2017) (20)
High Expression, Purification, and Properties of Recombinant Homocysteine α,γ-Lyase (1998) (19)
A simultaneous colorimetric assay of free and protein-coupled polyethylene glycol. (2003) (19)
Cimetidine: An inhibitor or promoter of tumor growth? (1999) (19)
Effective Metabolic Targeting of Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models with Recombinant Methioninase. (2017) (19)
Bone Marrow Mesenchymal Stem Cells Reverse Liver Damage in a Carbon Tetrachloride-induced Mouse Model of Chronic Liver Injury. (2016) (19)
The activity of camptothecin analogues is enhanced in histocultures of human tumors and human tumor xenografts by modulation of extracellular pH (2003) (19)
Hair growth in vitro from histocultured skin (1992) (19)
Engineered mesenchymal stem-cell-sheets patches prevents postoperative pancreatic leakage in a rat model (2018) (19)
In vivo serial selection of human pancreatic cancer cells in orthotopic mouse models produces high metastatic variants irrespective of Kras status. (2013) (19)
Single cell time-lapse imaging of focus formation by the DNA damage-response protein 53BP1 after UVC irradiation of human pancreatic cancer cells. (2013) (19)
Anomalous hepatic venous drainage into the left atrium: an unusual cause of hypoxemia. (2003) (19)
MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model. (2018) (19)
Detection of early colorectal cancer imaged with peanut agglutinin-immobilized fluorescent nanospheres having surface poly(N-vinylacetamide) chains. (2010) (19)
Clinical Studies of Methionine-Restricted Diets for Cancer Patients. (2019) (19)
Human tumor growth in nude mice is associated with decreased plasma cysteine and homocysteine. (2008) (19)
GFP-expressing vascularization of Gelfoam as a rapid in vivo assay of angiogenesis stimulators and inhibitors. (2007) (18)
The Tumor-Educated-Macrophage Increase of Malignancy of Human Pancreatic Cancer Is Prevented by Zoledronic Acid (2014) (18)
Comparison of three approaches to doxorubicin therapy: free doxorubicin, liposomal doxorubicin, and beta-glucuronidase-activated prodrug (HMR 1826). (2000) (18)
"Seed" to "soil" is a return trip in metastasis. (1995) (18)
DNA methylation levels in normal and chemically-transformed mouse 3T3 cells. (1982) (18)
Mobilization of bone marrow stem cells with StemEnhance improves muscle regeneration in cardiotoxin-induced muscle injury. (2010) (18)
MyD88 Regulates LPS-induced NF-ĸB/MAPK Cytokines and Promotes Inflammation and Malignancy in Colorectal Cancer Cells (2019) (18)
New sensitive discovery histoculture model for growth‐inhibition studies in prostate cancer and BPH (1998) (18)
Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence (2016) (18)
Ultrasound Microbubble Delivery Targeting Intraplaque Neovascularization Inhibits Atherosclerotic Plaque in an APOE-deficient Mouse Model (2018) (18)
A patient-derived orthotopic xenograft (PDOX) mouse model of a cisplatinum-resistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications for precision oncology (2017) (18)
Improved disease‐free survival and overall survival after fluorescence‐guided surgery of liver metastasis in an orthotopic nude mouse model (2015) (18)
Hair-follicle-associated pluripotent stem cells derived from cryopreserved intact human hair follicles sustain multilineage differentiation potential (2019) (18)
Dual-color, whole-body imaging in mice (2005) (18)
Dynamic subcellular imaging of cancer cell mitosis in the brain of live mice. (2013) (18)
Recent advances on in vivo imaging with fluorescent proteins. (2008) (18)
Subcellular real-time imaging of the efficacy of temozolomide on cancer cells in the brain of live mice. (2013) (17)
Antimetastatic activity of the new platinum analog [Pt(cis-dach) (DPPE).2NO3] in a metastatic model of human bladder cancer. (1997) (17)
Mitomycin C and cisplatin increase survival in a human pancreatic cancer metastatic model. (1997) (17)
Detection of Metastasis in a Patient-derived Orthotopic Xenograft (PDOX) Model of Undifferentiated Pleomorphic Sarcoma with Red Fluorescent Protein (2018) (17)
Managed care and the infectious diseases specialist. (1996) (17)
Doxorubicin-resistant pleomorphic liposarcoma with PDGFRA gene amplification is targeted and regressed by pazopanib in a patient-derived orthotopic xenograft mouse model. (2018) (17)
Back to the Future: Are Tumor-Targeting Bacteria the Next-Generation Cancer Therapy? (2015) (17)
Primer dosing of S. typhimurium A1-R potentiates tumor-targeting and efficacy in immunocompetent mice. (2013) (17)
Eribulin Suppressed Cisplatinum- and Doxorubicin-resistant Recurrent Lung Metastatic Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model (2019) (17)
Real-time imaging of apoptosis induction of human breast cancer cells by the traditional Chinese medicinal herb tubeimu. (2012) (17)
High-Resolution Magnetic Resonance Imaging of the Efficacy of the Cytosine Analogue 1-[2-C-Cyano-2-deoxy-β-d-arabino-pentofuranosyl]-N4-palmitoyl Cytosine (CS-682) in a Liver-Metastasis Athymic Nude Mouse Model (2003) (17)
Bugging tumors. (2012) (16)
Imaging the microenvironment of pancreatic cancer patient-derived orthotopic xenografts (PDOX) growing in transgenic nude mice expressing GFP, RFP, or CFP. (2016) (16)
Osteosarcoma Cells Enhance Angiogenesis Visualized by Color‐Coded Imaging in the In Vivo Gelfoam® Assay (2014) (16)
In vivo and in vitro effects of androgen on fibroblast growth factor‐2 concentrations in the human prostate (1994) (16)
Locally-applied 5-fluorouracil-loaded slow-release patch prevents pancreatic cancer growth in an orthotopic mouse model (2017) (16)
Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model (2018) (16)
Human hair-follicle associated pluripotent (hHAP) stem cells differentiate to cardiac-muscle cells (2017) (16)
Analysis of Two Complementary Single-Gene Deletion Mutant Libraries of Salmonella Typhimurium in Intraperitoneal Infection of BALB/c Mice (2016) (16)
Anti-metastatic Efficacy of Traditional Chinese Medicine (TCM) Ginsenoside Conjugated to a VEFGR-3 Antibody on Human Gastric Cancer in an Orthotopic Mouse Model. (2017) (16)
The hair follicle and its stem cells as drug delivery targets (2006) (16)
Imaging In Mice With Fluorescent Proteins: From Macro To Subcellular (2008) (16)
A combination of irinotecan/cisplatinum and irinotecan/temozolomide or tumor-targeting Salmonella typhimurium A1-R arrest doxorubicin- and temozolomide-resistant myxofibrosarcoma in a PDOX mouse model. (2018) (16)
Salmonella typhimurium A1-R tumor targeting in immunocompetent mice is enhanced by a traditional Chinese medicine herbal mixture. (2013) (16)
Regorafenib regressed a doxorubicin-resistant Ewing’s sarcoma in a patient-derived orthotopic xenograft (PDOX) nude mouse model (2019) (16)
Targeting neddylation inhibits intravascular survival and extravasation of cancer cells to prevent lung-cancer metastasis (2019) (16)
A novel anionic-phosphate-platinum complex effectively targets an undifferentiated pleomorphic sarcoma better than cisplatinum and doxorubicin in a patient-derived orthotopic xenograft (PDOX). (2017) (16)
Comparison of Nestin‐Expressing Multipotent Stem Cells in the Tongue Fungiform Papilla and Vibrissa Hair Follicle (2014) (15)
Imaging of Nucleolar Dynamics During the Cell Cycle of Cancer Cells in Live Mice (2007) (15)
Broad selective efficacy of rMETase and PEG-rMETase on cancer cells in vitro. (2010) (15)
Improved antibody-guided surgery with a near-infrared dye on a PEGylated linker for CEA-positive tumors (2019) (15)
A highly sensitive single-enzyme homocysteine assay (2008) (15)
Efficacy of Tumor-Targeting Salmonella typhimurium A1-R against Malignancies in Patient-Derived Orthotopic Xenograft (PDOX) Murine Models (2019) (15)
Methioninase: a therapeutic for diseases related to altered methionine metabolism and transmethylation: cancer, heart disease, obesity, aging, and Parkinson's disease. (1997) (15)
Green fluorescent protein to visualize cancer progression and metastasis. (1999) (15)
Temozolomide combined with irinotecan caused regression in an adult pleomorphic rhabdomyosarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model (2017) (15)
A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts (2016) (15)
The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model (2019) (15)
Real-Time Determination of the Cell-Cycle Position of Individual Cells within Live Tumors Using FUCCI Cell-Cycle Imaging (2018) (15)
Oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil regressed a colon cancer growing on the peritoneal surface in a patient-derived orthotopic xenograft mouse model. (2019) (15)
Isolation and culture of hair follicle pluripotent stem (hfPS) cells and their use for nerve and spinal cord regeneration. (2010) (15)
VEGF-C ShRNA inhibits pancreatic cancer growth and lymphangiogenesis in an orthotopic fluorescent nude mouse model. (2013) (15)
Development of a Clinically-Precise Mouse Model of Rectal Cancer (2013) (15)
Novel targets identified by integrated cancer-stromal interactome analysis of pancreatic adenocarcinoma. (2020) (15)
Stem‐like and non‐stem human pancreatic cancer cells distinguished by morphology and metastatic behavior (2011) (15)
Patient-derived orthotopic xenograft models of sarcoma. (2020) (15)
Intraoperative imaging of metastatic lymph nodes using a fluorophore-conjugated antibody in a HER2/neu-expressing orthotopic breast cancer mouse model. (2013) (15)
Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model (2018) (15)
Tumor‐Targeting Salmonella typhimurium A1‐R Promotes Tumoricidal CD8+ T Cell Tumor Infiltration and Arrests Growth and Metastasis in a Syngeneic Pancreatic‐Cancer Orthotopic Mouse Model (2018) (15)
Recombinant human interferon alpha-2a increases 5-fluorouracil efficacy by elevating fluorouridine concentration in tumor tissue. (1994) (15)
DNA methylation in normal and SV40-transformed human fibroblasts. (1981) (15)
Color-coded imaging of splenocyte-pancreatic cancer cell interactions in the tumor microenvironment (2008) (15)
Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models (2015) (14)
Similarity of serum-tumor pharmacokinetics of antitumor agents in man and nude mice. (1993) (14)
Fluorescence-guided hepatobiliary surgery with long and short wavelength fluorophores. (2020) (14)
Enhanced resection of orthotopic red-fluorescent-protein-expressing human glioma by fluorescence-guided surgery in nude mice. (2013) (14)
Tumor-targeting Salmonella typhimurium A1-R inhibits human prostate cancer experimental bone metastasis in mouse models (2015) (14)
Pilot Phase I Clinical Trial of Methioninase on High-Stage Cancer Patients: Rapid Depletion of Circulating Methionine. (2019) (14)
Analysis of Stroma Labeling During Multiple Passage of a Sarcoma Imageable Patient‐Derived Orthotopic Xenograft (iPDOX) in Red Fluorescent Protein Transgenic Nude Mice (2017) (14)
Strategies for In Vivo Imaging Using Fluorescent Proteins (2017) (14)
Chemo-resistant Gastric Cancer Associated Gene Expression Signature: Bioinformatics Analysis Based on Gene Expression Omnibus (2019) (14)
Ethanolic Extract of Traditional Chinese Medicine (TCM) Gamboge Inhibits Colon Cancer via the Wnt/Beta-Catenin Signaling Pathway in an Orthotopic Mouse Model. (2018) (14)
Combination efficacy of doxorubicin and adenoviral methioninase gene therapy with prodrug selenomethionine. (2003) (14)
Imaging of cell trafficking and metastases of paediatric rhabdomyosarcoma (2008) (14)
Maintenance of expression of tumor antigens in three-dimensional in vitro human tumor gel-supported histoculture. (1991) (14)
Therapeutic Efficacy of the Traditional Chinese Medicine Baishaoqiwu on TNBS-induced Colitis is Associated with Down-regulation of the TLR4/MyD88/NF-κB Signaling Pathway. (2016) (14)
Whole-body fluorescence imaging with green fluorescence protein. (2002) (14)
A Dual-Color Genetically Engineered Mouse Model for Multispectral Imaging of the Pancreatic Microenvironment (2013) (14)
Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model. (2019) (14)
Double-negative T Cells Inhibit Proliferation and Invasion of Human Pancreatic Cancer Cells in Co-culture (2019) (14)
Oral Methioninase Inhibits Recurrence in a PDOX Mouse Model of Aggressive Triple-negative Breast Cancer (2020) (14)
The Experience of Greece as a Model to Contain COVID-19 Infection Spread (2021) (14)
Hair Follicle-Associated Pluripotent(HAP) Stem Cells. (2018) (14)
FUCCI Real-Time Cell-Cycle Imaging as a Guide for Designing Improved Cancer Therapy: A Review of Innovative Strategies to Target Quiescent Chemo-Resistant Cancer Cells (2020) (13)
Fluorescent-Antibody Targeting of Insulin-Like Growth Factor-1 Receptor Visualizes Metastatic Human Colon Cancer in Orthotopic Mouse Models (2016) (13)
Tumor targeting Salmonella typhimurium A1-R in combination with gemcitabine (GEM) regresses partially GEM-resistant pancreatic cancer patient-derived orthotopic xenograft (PDOX) nude mouse models (2018) (13)
Use of fluorescent proteins and color-coded imaging to visualize cancer cells with different genetic properties (2016) (13)
Color-coded Live Imaging of Heterokaryon Formation and Nuclear Fusion of Hybridizing Cancer Cells. (2016) (13)
L-[Methyl-11C] Methionine-Positron-Emission Tomography (MET-PET). (2019) (13)
Aurora-A/NF-ĸB Signaling Is Associated With Radio-resistance in Human Lung Adenocarcinoma (2019) (13)
The combination of 5-FU, leucovorin and CPT-11 (FOLFIRI) prolongs survival through inhibition of metastasis in an orthotopic model of colon cancer. (2010) (13)
Temozolomide regresses a doxorubicin‐resistant undifferentiated spindle‐cell sarcoma patient‐derived orthotopic xenograft (PDOX): precision‐oncology nude‐mouse model matching the patient with effective therapy (2018) (13)
Future of Bacterial Therapy of Cancer. (2016) (13)
Oral-recombinant Methioninase Converts an Osteosarcoma from Docetaxel-resistant to -Sensitive in a Clinically-relevant Patient-derived Orthotopic-xenograft (PDOX) Mouse Model (2021) (13)
Nestin-expressing stem cells from the hair follicle can differentiate into motor neurons and reduce muscle atrophy after transplantation to injured nerves. (2013) (13)
Visualizing portal vein metastatic trafficking to the liver with green fluorescent protein-expressing tumor cells. (2004) (13)
Syngeneic lymph-node-targeting model of green fluorescent protein-expressing Lewis lung carcinoma (2005) (13)
Implanted hair-follicle-associated pluripotent (HAP) stem cells encapsulated in polyvinylidene fluoride membrane cylinders promote effective recovery of peripheral nerve injury (2017) (13)
Fluorescence-guided surgery of prostate cancer bone metastasis. (2014) (13)
Oral Recombinant Methioninase Prevents Obesity in Mice on a High-fat Diet (2020) (13)
The cyan fluorescent protein (CFP) transgenic mouse as a model for imaging pancreatic exocrine cells. (2009) (13)
Genetic and metabolic comparison of orthotopic and heterotopic patient-derived pancreatic-cancer xenografts to the original patient tumors (2017) (13)
Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model (2015) (13)
Eribulin regresses a doxorubicin‐resistant Ewing's sarcoma with a FUS‐ERG fusion and CDKN2A‐deletion in a patient‐derived orthotopic xenograft (PDOX) nude mouse model (2018) (13)
Gemcitabine combined with docetaxel precisely regressed a recurrent leiomyosarcoma peritoneal metastasis in a patient-derived orthotopic xenograft (PDOX) model. (2019) (13)
Fluorescent proteins as visible in vivo sensors. (2013) (13)
Enhancement of Wound Healing by the Traditional Chinese Medicine Herbal Mixture Sophora flavescens in a Rat Model of Perianal Ulceration. (2017) (12)
A patient‐derived orthotopic xenograft (PDOX) nude‐mouse model precisely identifies effective and ineffective therapies for recurrent leiomyosarcoma (2019) (12)
Patterns of sensitivity to a panel of drugs are highly individualised for undifferentiated/unclassified soft tissue sarcoma (USTS) in patient-derived orthotopic xenograft (PDOX) nude-mouse models (2018) (12)
Pathological Validity of Using Near-infrared Fluorescence Imaging for Securing Surgical Margins During Liver Resection (2020) (12)
Tumor imaging technologies in mouse models. (2015) (12)
Tumor-specific near-infrared nanobody probe rapidly labels tumors in an orthotopic mouse model of pancreatic cancer. (2020) (12)
Embryonic development of hair follicle pluripotent stem (hfPS) cells (2010) (12)
Tumor relapse prevented by combining adoptive T cell therapy with Salmonella typhimurium (2016) (12)
Interferon gamma is highly effective against orthotopically-implanted human pleural adenocarcinoma in nude mice. (1996) (12)
Inhibition of growth and metastasis of triple-negative breast cancer targeted by Traditional Chinese Medicine Tubeimu in orthotopic mice models. (2018) (12)
BRCAness and Prognosis in Triple-Negative Breast Cancer Patients Treated with Neoadjuvant Chemotherapy (2016) (12)
High accuracy of mesoscopic epi-fluorescence tomography for non-invasive quantitative volume determination of fluorescent protein-expressing tumours in mice (2012) (12)
Color-coded intravital imaging demonstrates a transforming growth factor-β (TGF-β) antagonist selectively targets stromal cells in a human pancreatic-cancer orthotopic mouse model (2017) (12)
Major liver resection stimulates stromal recruitment and metastasis compared with repeated minor resection. (2012) (12)
Individualized doxorubicin sensitivity testing of undifferentiated soft tissue sarcoma (USTS) in a patient-derived orthotopic xenograft (PDOX) model demonstrates large differences between patients (2018) (12)
High antimetastatic efficacy of MEN4901/T-0128, a novel camptothecin carboxymethyldextran conjugate. (2011) (12)
S-adenosylmethionine synthetase in cultured normal and oncogenically-transformed human and rat cells. (1983) (12)
Lowering and Stabilizing PSA Levels in Advanced-prostate Cancer Patients With Oral Methioninase (2021) (12)
Comparative chemosensitivity of circulating human prostate cancer cells and primary cancer cells. (2012) (12)
Extended-working-distance multiphoton micromanipulation microscope for deep-penetration imaging in live mice and tissue. (2009) (12)
High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models (2016) (12)
Hypoxia Enhances Differentiation of Hair Follicle‐Associated‐Pluripotent (HAP) Stem Cells to Cardiac‐Muscle Cells (2017) (12)
Epstein-Barr HR-1 Virion DNA Is Very Highly Methylated (1983) (11)
Color-coded Imaging of the Fate of Cancer-cell-derived Exosomes During Pancreatic Cancer Metastases in a Nude-mouse Model (2019) (11)
Early Reporting of Apoptosis by Real-time Imaging of Cancer Cells Labeled with Green Fluorescent Protein in the Nucleus and Red Fluorescent Protein in the Cytoplasm. (2015) (11)
In vivo real‐time imaging of nuclear‐cytoplasmic dynamics of dormancy, proliferation and death of cancer cells (2008) (11)
Anti-Claudin-1 Conjugated to a Near-Infrared Fluorophore Targets Colon Cancer in PDOX Mouse Models. (2019) (11)
Osteosarcoma Patient-derived Orthotopic Xenograft (PDOX) Models Used to Identify Novel and Effective Therapeutics: A Review (2021) (11)
Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models (2016) (11)
Site‐specific cytomorphology of disseminated PC‐3 prostate cancer cells visualized in vivo with fluorescent proteins (2013) (11)
In vivo imaging of pancreatic cancer with fluorescent proteins in mouse models. (2012) (11)
Prostate Cancer Metastases Are Strongly Inhibited by Agonistic Epha2 Ligands in an Orthotopic Mouse Model (2020) (11)
A novel approach to gene therapy of albino hair in histoculture with a retroviral streptomyces tyrosinase gene. (2000) (11)
Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model. (2019) (11)
In Vivo Isolation of a Highly-aggressive Variant of Triple-negative Human Breast Cancer MDA-MB-231 Using Serial Orthotopic Transplantation. (2016) (11)
Histoculture and the immunodeficient mouse come to the cancer clinic - rational approaches to individualizing cancer-therapy and new drug-evaluation (review). (1992) (11)
Antimetastatic intraoperative chemotherapy of human colon tumors in the livers of nude mice. (2000) (11)
The preparation of endotoxin-free L-methionine-alpha-deamino-gamma-mercaptomethane-lyase (L-methioninase) from Pseudomonas putida. (1993) (11)
Efficacy of new platinum analog DPPE in an orthotopic nude mouse model of human colon cancer. (1999) (11)
Traditional Chinese medicine herbal mixture LQ arrests FUCCI-expressing HeLa cells in G0/G1 phase in 2D plastic, 2.5D Matrigel®, and 3D Gelfoam® culture visualized with FUCCI imaging (2015) (10)
Comparison of GFP-Expressing Imageable Mouse Models of Human Esophageal Squamous Cell Carcinoma Established in Various Anatomical Sites. (2015) (10)
Cellular and subcellular imaging in live mice using fluorescent proteins. (2012) (10)
Antimetastatic efficacy of oral 5-FU imaged by green fluorescent protein in real time. (2003) (10)
Real-time imaging of αv integrin molecular dynamics in osteosarcoma cells in vitro and in vivo. (2013) (10)
Combination Methionine-methylation-axis Blockade: A Novel Approach to Target the Methionine Addiction of Cancer (2021) (10)
Homogeneous enzymatic colorimetric assay for total cysteine. (2004) (10)
Comparison of μCT, MRI and optical reflectance imaging for assessing the growth of GFP/RFP-expressing tumors. (2011) (10)
Oral Methioninase for Covid-19 Methionine-restriction Therapy. (2020) (10)
Interleukin-6 production in primary histoculture by normal human kidney and renal tumor tissues. (1997) (10)
The preparation of [35S]homocysteine thiolactone free of [35S]methionine. (1982) (10)
Inhibition of metastasis of circulating human prostate cancer cells in the chick embryo by an extracellular matrix produced by foreskin fibroblasts in culture. (2012) (10)
A color-coded imaging model of the interaction of αv integrin-GFP expressed in osteosarcoma cells and RFP expressing blood vessels in Gelfoam® vascularized in vivo. (2013) (10)
Model of selective gene therapy of hair growth: Liposome targeting of the active lac-z gene to hair follicles of histocultured skin (2007) (10)
Regorafenib regresses an imatinib-resistant recurrent gastrointestinal stromal tumor (GIST) with a mutation in exons 11 and 17 of c-kit in a patient-derived orthotopic xenograft (PDOX) nude mouse model (2018) (10)
Comparison of glucose-consumption and thymidine-incorporation endpoints in histocultured human superficial bladder tumors. (1994) (10)
Lectin-immobilized fluorescent nanospheres for targeting to colorectal cancer from a physicochemical perspective. (2011) (10)
Tumor-targeting Salmonella typhimurium A1-R suppressed an imatinib-resistant gastrointestinal stromal tumor with c-kit exon 11 and 17 mutations (2018) (10)
A Color-coded Imageable Syngeneic Mouse Model of Stromal-cell Recruitment by Metastatic Lymphoma. (2015) (10)
Extent and Instability of Trimethylation of Histone H3 Lysine Increases With Degree of Malignancy and Methionine Addiction (2021) (10)
Choline-Deficient-Diet-Induced Fatty Liver Is a Metastasis-Resistant Microenvironment. (2017) (10)
Near-infrared photoimmunotherapy is effective treatment for colorectal cancer in orthotopic nude-mouse models (2020) (9)
Fluorescence-Guided Surgery of Retroperitoneal-Implanted Human Fibrosarcoma in Nude Mice Delays or Eliminates Tumor Recurrence and Increases Survival Compared to Bright-Light Surgery (2015) (9)
Temozolomide targets and arrests a doxorubicin-resistant follicular dendritic-cell sarcoma patient-derived orthotopic xenograft mouse model. (2019) (9)
Noncolorimetric measurement of cell activity in three-dimensional histoculture using the tetrazolium dye 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide: the pixel image analysis of formazan crystals. (1992) (9)
Specific tumor labeling enhanced by polyethylene glycol linkage of near infrared dyes conjugated to a chimeric anti-carcinoembryonic antigen antibody in a nude mouse model of human pancreatic cancer (2014) (9)
Tumor-targeting Salmonella typhimurium A1-R overcomes nab-paclitaxel resistance in a cervical cancer PDOX mouse model (2019) (9)
Triple-Methyl Blockade With Recombinant Methioninase, Cycloleucine, and Azacitidine Arrests a Pancreatic Cancer Patient-Derived Orthotopic Xenograft Model (2021) (9)
A novel anionic-phosphate-platinum complex effectively targets an undifferentiated pleomorphic sarcoma better than cisplatinum and doxorubicin in a patient-derived orthotopic xenograft (PDOX) (2017) (9)
Response of Triple-negative Breast Cancer Liver Metastasis to Oral Recombinant Methioninase in a Patient-derived Orthotopic Xenograft (PDOX) Model (2020) (9)
Lowered Respiratory Response to Adenosine Diphosphate of Mitochondria Isolated from a Mutant B Strain of Schizophyllum commune (1972) (9)
Chapter 2. Color-coded fluorescent mouse models of cancer cell interactions with blood vessels and lymphatics. (2008) (9)
Andrographolide Induces Noxa-Dependent Apoptosis by Transactivating ATF4 in Human Lung Adenocarcinoma Cells (2021) (9)
Bacterial Therapy of Cancer (2016) (9)
Nestin-driven green fluorescent protein as an imaging marker for nascent blood vessels in mouse models of cancer. (2011) (9)
Comparison of cancer-cell seeding, viability and deformation in the lung, muscle and liver, visualized by subcellular real-time imaging in the live mouse. (2011) (9)
Expression of anti-aging type-XVII collagen (COL17A1/BP180) in hair follicle-associated pluripotent (HAP) stem cells during differentiation. (2019) (9)
Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models (2015) (9)
Toxicology and efficacy of tumor-targeting Salmonella typhimurium A1-R compared to VNP 20009 in a syngeneic mouse tumor model in immunocompetent mice. (2017) (9)
siRNA Targeting of MDR1 Reverses Multidrug Resistance in a Nude Mouse Model of Doxorubicin-resistant Human Hepatocellular Carcinoma. (2016) (9)
Antimetastatic Efficacy of the Combination of Caffeine and Valproic Acid on an Orthotopic Human Osteosarcoma Cell Line Model in Nude Mice. (2017) (9)
Fluorescence‐guided surgery of human prostate cancer experimental bone metastasis in nude mice using anti‐CEA DyLight 650 for tumor illumination (2016) (8)
The First Mouse Model of Primary Osteosarcoma of the Breast (2021) (8)
Imaging the Role of Multinucleate Pancreatic Cancer Cells and Cancer-Associated Fibroblasts in Peritoneal Metastasis in Mouse Models. (2017) (8)
Fertile Seed and Rich Soil (1997) (8)
Toxicology and efficacy of tumor-targeting Salmonella typhimurium A1-R compared to VNP 20009 in a syngeneic mouse tumor model in immunocompetent mice (2017) (8)
RT-PCR of peritoneal washings predicts peritoneal pancreatic cancer recurrence. (2018) (8)
Tumor-targeting Salmonella typhimurium A1-R overcomes partial carboplatinum-resistance of a cancer of unknown primary (CUP). (2018) (8)
Specificity of lectin-immobilized fluorescent nanospheres for colorectal tumors in a mouse model which better resembles the clinical disease. (2015) (8)
Aging hair follicles rejuvenated by transplantation to a young subcutaneous environment (2016) (8)
Peritoneal Metastases in a Patient-derived Orthotopic Xenograft (PDOX) Model of Colon Cancer Imaged Non-invasively via Red Fluorescent Protein Labeled Stromal Cells (2019) (8)
Clinically-relevent orthotopic metastatic models of pancreatic cancer imageable with fluorescent genetic reporters. (2009) (8)
Imaging of the interaction of cancer cells and the lymphatic system. (2011) (8)
An mTOR and VEGFR inhibitor combination arrests a doxorubicin resistant lung metastatic osteosarcoma in a PDOX mouse model (2021) (8)
Co-implantation of Tumor and Extensive Surrounding Tissue Improved the Establishment Rate of Surgical Specimens of Human-Patient Cancer in Nude Mice: Toward the Goal of Universal Individualized Cancer Therapy (2020) (8)
The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model. (2019) (8)
In Vivo Selection of Intermediately- and Highly-Malignant Variants of Triple-negative Breast Cancer in Orthotopic Nude Mouse Models. (2016) (8)
Non-toxic Efficacy of the Combination of Caffeine and Valproic Acid on Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models. (2016) (8)
Linkage of methionine addiction, histone lysine hypermethylation, and malignancy (2022) (8)
Humanized Anti-Tumor-Associated Glycoprotein-72 for Submillimeter Near-Infrared Detection of Colon Cancer in Metastatic Mouse Models. (2020) (8)
High-Mobility Group Box 1 expression predicts survival of patients after resection of adenocarcinoma of the ampulla of Vater (2019) (8)
Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Can Extensively Differentiate to Tyrosine-Hydroxylase-Expressing Dopamine-Secreting Neurons (2021) (8)
In vivo imaging of nuclear‐cytoplasmic deformation and partition during cancer cell death due to immune rejection (2012) (8)
TRAF6-Mediated Inflammatory Cytokines Secretion in LPS-induced Colorectal Cancer Cells Is Regulated by miR-140 (2019) (8)
Peripheral-Nerve and Spinal-Cord Regeneration in Mice Using Hair-Follicle-Associated Pluripotent (HAP) Stem Cells. (2016) (8)
Osimertinib Regresses an EGFR-Mutant Cisplatinum- Resistant Lung Adenocarcinoma Growing in the Brain in Nude Mice (2019) (8)
Biological ablation of sentinel lymph node metastasis in submucosally invaded early gastrointestinal cancer. (2015) (8)
Decreased Expression of Tumor-suppressor Gene LKB1 Correlates with Poor Prognosis in Human Gastric Cancer. (2016) (8)
Splenectomy is associated with an aggressive tumor growth pattern and altered host immunity in an orthotopic syngeneic murine pancreatic cancer model (2017) (8)
Efficacy of Oral Recombinant Methioninase and Eribulin on a PDOX Model of Triple-negative Breast Cancer (TNBC) Liver Metastasis (2021) (8)
Correlation of drug response in human tumors histocultured in vitro with an image-analysis MTT end point and in vivo xenografted in nude mice. (1992) (8)
Efficacy of intra-hepatectomy 5-FU on recurrence and metastasis of human hepatocellular carcinoma in nude mice. (2001) (8)
The disintegrin echistatin in combination with doxorubicin targets high-metastatic human osteosarcoma overexpressing αvβ3 integrin in chick embryo and nude mouse models (2016) (8)
Blood-bank testing for infectious diseases: how safe is blood transfusion? (2002) (8)
Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Encapsulated on Polyvinylidene Fluoride Membranes (PFM) Promote Functional Recovery from Spinal Cord Injury (2018) (8)
Specific route mapping visualized with GFP of single‐file streaming contralateral and systemic metastasis of Lewis lung carcinoma cells beginning within hours of orthotopic implantion (2013) (8)
High-resolution magnetic resonance imaging of the efficacy of the cytosine analogue 1-[2-C-cyano-2-deoxy-beta-D-arabino-pentofuranosyl]-N(4)-palmitoyl cytosine (CS-682) in a liver-metastasis athymic nude mouse model. (2003) (8)
The combination of gemcitabine and docetaxel arrests a doxorubicin-resistant dedifferentiated liposarcoma in a patient-derived orthotopic xenograft model. (2019) (7)
Color coding cancer cells with fluorescent proteins to visualize in vivo cellular interaction in metastatic colonies. (2004) (7)
β-Catenin Expression Correlates With Prognosis in Hepatocellular Carcinoma Patients Treated With Transcatheter Arterial Chemoembolization (2019) (7)
Selective induction of apoptosis in the hamster flank sebaceous gland organ by a topical liposome 5‐α‐reductase inhibitor: A treatment strategy for acne (2010) (7)
Traditional Chinese Medicine Brucea Javanica Oil Enhances the Efficacy of Anlotinib in a Mouse Model of Liver-Metastasis of Small-cell Lung Cancer (2021) (7)
Fangchinoline Inhibits Human Esophageal Cancer by Transactivating ATF4 to Trigger Both Noxa-Dependent Intrinsic and DR5-Dependent Extrinsic Apoptosis (2021) (7)
Genetic Impairment of Energy Conservation in Development of Schizophyllum: Efficient Mitochondria in Energy-starved Cells (1974) (7)
The combination of olaratumab with gemcitabine and docetaxel arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft mouse model (2019) (7)
Early-age-dependent selective decrease of differentiation potential of hair-follicle-associated pluripotent (HAP) stem cells to beating cardiac-muscle cells (2016) (7)
Eribulin Regresses a Cisplatinum-resistant Rare-type Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft Mouse Model (2020) (7)
Alveolar macrophage migration after lung transplantation. (1991) (7)
Real-time imaging of tumor progression in a fluorescent orthotopic mouse model of thyroid cancer. (2010) (7)
AMMECR1 Inhibits Apoptosis and Promotes Cell-cycle Progression and Proliferation of the A549 Human Lung Cancer Cell Line (2019) (7)
Protein carboxyl amidation increases the potential extent of protein polyethylene glycol conjugation. (2004) (7)
The Anti-oxidant Monoterpene p-Cymene Reduced the Occurrence of Colorectal Cancer in a Hyperlipidemia Rat Model by Reducing Oxidative Stress and Expression of Inflammatory Cytokines (2021) (7)
Transgenic nude mice ubiquitously expressing fluorescent proteins for color-coded imaging of the tumor microenvironment. (2014) (7)
Effect of the polygalacturonase inhibitor from pea on the hydrolysis of pea cell walls by the endopolygalacturonase from Ascochyta pisi (1985) (7)
Color-Coded Imaging of Syngeneic Orthotopic Malignant Lymphoma Interacting with Host Stromal Cells During Metastasis. (2016) (7)
Multipotent Stem Cells of the Hair Follicle (2016) (7)
Altered Methionine Metabolism in Cancer Cells. (2019) (7)
Fluorescent Orthotopic Mouse Model of Pancreatic Cancer. (2016) (7)
Color‐Coded Fluorescence Imaging of Lymph‐Node Metastasis, Angiogenesis, and Its Drug‐Induced Inhibition (2014) (7)
High Efficacy of Recombinant Methioninase on Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Cancer. (2019) (7)
Eradication of melanoma in vitro and in vivo via targeting with a Killer-Red-containing telomerase-dependent adenovirus (2017) (7)
Nonradioactive enzymatic assay for plasma and serum vitamin B6 (2008) (7)
Pazopanib Inhibits Tumor Growth, Lymph-node Metastasis and Lymphangiogenesis of an Orthotopic Mouse of Colorectal Cancer (2020) (7)
Knockdown of Histone Methyltransferase WHSC1 Induces Apoptosis and Inhibits Cell Proliferation and Tumorigenesis in Salivary Adenoid Cystic Carcinoma (2019) (7)
Protocols for Cryopreservation of Intact Hair Follicle That Maintain Pluripotency of Nestin-Expressing Hair-Follicle-Associated Pluripotent (HAP) Stem Cells. (2016) (7)
Enhancing magnetic resonance imaging tumor detection with fluorescence intensity and lifetime imaging. (2010) (7)
Crystallization and preliminary crystallographic characterization of recombinant l-methionine-α-deamino-γ-mercaptomethane lyase (methioninase) (2000) (7)
Enhanced Metastatic Recurrence Via Lymphatic Trafficking of a High‐Metastatic Variant of Human Triple‐Negative Breast Cancer After Surgical Resection in Orthotopic Nude Mouse Models (2017) (7)
A Novel Anionic-phosphate-platinum Complex Effectively Targets a Cisplatinum-resistant Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model (2020) (7)
The Use of Living Cancer Cells Expressing Green Fluorescent Protein in the Nucleus and Red Fluorescence Protein in the Cytoplasm for Real-time Confocal Imaging of Chromosome and Cytoplasmic Dynamics During Mitosis. (2015) (7)
Fluorescence-Guided Surgery of Liver Metastasis in Orthotopic Nude-Mouse Models (2015) (7)
Color-coded Imaging of the Circulating Tumor Cell Microenvironment (2018) (6)
Complementarity of variable-magnification and spectral-separation fluorescence imaging systems for noninvasive detection of metastasis and intravital detection of single cancer cells in mouse models. (2015) (6)
Detection of colon cancer metastases with fluorescence laparoscopy in orthotopic nude mouse models. (2012) (6)
A Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft (PDOX) Mouse Model Is Sensitive to Bevacizumab and Vinorelbine, Regressed by Eribulin and Resistant to Olaparib (2020) (6)
NEDD8-conjugating enzyme UBC12 as a novel therapeutic target in esophageal squamous cell carcinoma (2020) (6)
Real Time Metastatic Route Tracking of Orthotopic PC‐3‐GFP Human Prostate Cancer Using Intravital Imaging (2016) (6)
Independence of cytotoxic drug sensitivity profiles and receptor subtype of invasive ductal breast carcinoma demonstrated by the histoculture drug response assay (HDRA). (2014) (6)
Effects of siRNA Silencing of TUG1 and LCAL6 Long Non-coding RNAs on Patient-derived Xenograft of Non-small Cell Lung Cancer. (2018) (6)
A Novel Color-Coded Liver Metastasis Mouse Model to Distinguish Tumor and Adjacent Liver Segment. (2021) (6)
A novel patient-derived orthotopic xenograft (PDOX) mouse model of highly-aggressive liver metastasis for identification of candidate effective drug-combinations (2020) (6)
Induction of Metastasis by Low-dose Gemcitabine in a Pancreatic Cancer Orthotopic Mouse Model: An Opposite Effect of Chemotherapy (2019) (6)
Tumor-Specific S/G2-Phase Cell Cycle Arrest of Cancer Cells by Methionine Restriction. (2019) (6)
Effective targeting of the ubiquitin-like modifier NEDD8 for lung adenocarcinoma treatment (2020) (6)
Development of Recombinant Methioninase for Cancer Treatment. (2019) (6)
Comment re: Preclinical model of spontaneous melanoma metastasis. (2009) (6)
Imaging nuclear - cytoplasm dynamics of cancer cells in the intravascular niche of live mice. (2013) (6)
Extensive Hair-Shaft Elongation by Isolated Mouse Whisker Follicles in Very Long-Term Gelfoam® Histoculture (2015) (6)
Live cell imaging in live animals with fluorescent proteins. (2012) (6)
Efficacy In Vitro of Caffeine and Valproic Acid on Patient-Derived Undifferentiated Pleomorphic Sarcoma and Rhabdomyosarcoma Cell Lines. (2017) (6)
Tumor-Specific Fluorescent Antibody Imaging Enables Accurate Staging Laparoscopy in an Orthotopic Model of Pancreatic Cancer (2014) (6)
Color-coded imaging of spontaneous vessel anastomosis in vivo. (2013) (6)
Oral Recombinant Methioninase Inhibits Diabetes Onset in Mice on a High-fat Diet (2020) (6)
In Vivo Cellular Imaging Using Fluorescent Proteins (2012) (6)
Visualizing the Tumor Microenvironment by Color-coded Imaging in Orthotopic Mouse Models of Cancer. (2018) (6)
Over-methylation of Histone H3 Lysines Is a Common Molecular Change Among the Three Major Types of Soft-tissue Sarcoma in Patient-derived Xenograft (PDX) Mouse Models (2021) (6)
Indocyanine Green Labels an Orthotopic Nude-Mouse Model of Very-Early Colon-Cancer Liver Metastases (2020) (6)
Heterogeneous cell-cycle behavior in response to UVB irradiation by a population of single cancer cells visualized by time-lapse FUCCI imaging (2015) (6)
ISOLATION AND PARTIAL CHARCTERIZATION OF A MUTANT OF PENICILLIUM FOR THE SACCHARIFICATION OF STRAW (1985) (6)
APELA/ELA32 Reduces Iodixanol-induced Apoptosis, Inflammatory Response and Mitochondrial and DNA Damage in Renal Tubular Epithelial Cells (2020) (6)
Extensive Hair Shaft Growth after Mouse Whisker Follicle Isolation, Cryopreservation and Transplantation in Nude Mice (2015) (6)
Combination of CDK4/6 and mTOR Inhibitors Suppressed Doxorubicin-resistant Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model: A Translatable Strategy for Recalcitrant Disease (2021) (6)
Imaging metastatic cell trafficking at the cellular level in vivo with fluorescent proteins. (2014) (6)
Real-Time Fluorescence Image-Guided Oncolytic Virotherapy for Precise Cancer Treatment (2021) (6)
Tumor growth control with IDO-silencing Salmonella--letter. (2013) (6)
Oral Recombinant Methioninase Prevents Nonalcoholic Fatty Liver Disease in Mice on a High Fat Diet (2020) (6)
Moesin Up-regulation Is Associated with Enhanced Tumor Progression Imaged Non-invasively in an Orthotopic Mouse Model of Human Glioblastoma (2018) (6)
Oral Recombinant Methioninase Sensitizes a Bladder Cancer Orthotopic Xenograft Mouse Model to Low-dose Cisplatinum and Prevents Metastasis (2020) (5)
Exquisite Tumor Targeting by Salmonella A1-R in Combination with Caffeine and Valproic Acid Regresses an Adult Pleomorphic Rhabdomyosarcoma Patient-Derived Orthotopic Xenograft Mouse Model (2019) (5)
Surgical and histological boundary of the hepatic hilar plate system: basic study relevant to surgery for hilar cholangiocarcinoma regarding the “true” proximal ductal margin (2019) (5)
Tumor‐targeting Salmonella typhimurium A1‐R arrests a doxorubicin‐resistant PDGFRA‐amplified patient‐derived orthotopic xenograft mouse model of pleomorphic liposarcoma (2018) (5)
Color-coded Imaging Enables Fluorescence-guided Surgery to Resect the Tumor Along with the Tumor Microenvironment in a Syngeneic Mouse Model of EL-4 Lymphoma. (2016) (5)
Clinical Factors That Affect the Establishment of Soft Tissue Sarcoma Patient-Derived Orthotopic Xenografts: A University of California, Los Angeles, Sarcoma Program Prospective Clinical Trial. (2017) (5)
Genetic Recombination Between Stromal and Cancer Cells Results in Highly Malignant Cells Identified by Color‐Coded Imaging in a Mouse Lymphoma Model (2017) (5)
Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy, and tumor-targeting S. typhimurium A1-R is superior to first-line chemotherapy (2018) (5)
A Novel Procedure for Orthotopic Tibia Implantation for Establishment of a More Clinical Osteosarcoma PDOX Mouse Model (2021) (5)
Use of GFP for in vivo imaging: concepts and misconceptions (2008) (5)
Efficacy of the platinum analog [Pt(cis-dach)(DPPE)-2NO3] on histocultured human patient bladder tumors and cancer cell lines. (1996) (5)
Reversion from Methionine Addiction to Methionine Independence Results in Loss of Tumorigenic Potential of Highly-malignant Lung-cancer Cells (2021) (5)
Color-coded Imaging Distinguishes Cancer Cells, Stromal Cells, and Recombinant Cancer-stromal Cells in the Tumor Microenvironment During Metastasis (2018) (5)
Brucea javanica Increases Survival and Enhances Gemcitabine Efficacy in a Patient-derived Orthotopic Xenograft (PDOX) Mouse Model of Pancreatic Cancer (2020) (5)
Combined effect of 5-fluorouracil and carboplatin against human gastric cancer cell lines in vitro and in vivo. (1994) (5)
Imaging the interaction of αv integrin‐GFP in osteosarcoma cells with RFP‐expressing host stromal cells and tumor‐scaffold collagen in the primary and metastatic tumor microenvironment (2018) (5)
Therapeutic Cell‐Cycle‐Decoy Efficacy of a Telomerase‐Dependent Adenovirus in an Orthotopic Model of Chemotherapy‐Resistant Human Stomach Carcinomatosis Peritonitis Visualized With FUCCI Imaging (2016) (5)
Abstract 4373: Color-coded real-time imaging of the interaction of mesenchymal stem cells and cancer cells (2011) (5)
A Single Low Dose of Eribulin Regressed a Highly Aggressive Triple-negative Breast Cancer in a Patient-derived Orthotopic Xenograft Model (2020) (5)
Oral-recombinant Methioninase Converts an Osteosarcoma from Methotrexate-resistant to -sensitive in a Patient-derived Orthotopic-xenograft (PDOX) Mouse Model (2022) (5)
Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models (2016) (5)
Adjuvant Oral Recombinant Methioninase Inhibits Lung Metastasis in a Surgical Breast-Cancer Orthotopic Syngeneic Model (2020) (5)
Clinical Correlation of the Histoculture Drug Response Assay for Head and Neck Cancer. (2018) (5)
Folate polyglutamate and monoglutamate accumulation in normal and SV40‐transformed human fibroblasts (1981) (5)
Methionine Restriction: Ready for Prime Time in the Cancer Clinic? (2022) (5)
Tumor-sealing Surgical Orthotopic Implantation of Human Colon Cancer in Nude Mice Induces Clinically-relevant Metastases Without Early Peritoneal Carcinomatosis (2019) (5)
Temozolomide and Pazopanib Combined with FOLFOX Regressed a Primary Colorectal Cancer in a Patient-derived Orthotopic Xenograft Mouse Model (2020) (5)
Cancer-specific overmethylation of histone H3 lysines is necessary for methionine addiction and malignancy (2020) (5)
Metastatic orthotopic mouse models of lung cancer. (2003) (5)
High expression, purification, and properties of recombinant homocysteine alpha, gamma-lyase. (1998) (5)
Comparison of Tumor Recurrence After Resection of Highly- and Poorly-Metastatic Triple-negative Breast Cancer in Orthotopic Nude-Mouse Models. (2017) (5)
Real-time subcellular imaging in live animals: new visible targets for cancer drug discovery. (2006) (5)
Real‐Time In Vivo Confocal Fluorescence Imaging of Prostate Cancer Bone‐Marrow Micrometastasis Development at the Cellular Level in Nude Mice (2016) (5)
The stem cell mobilizer StemEnhance does not promote tumor growth in an orthotopic model of human breast cancer. (2009) (5)
3D Sponge-Matrix Histoculture: An Overview. (2018) (5)
Study of action of cyclophosphamide and extract of mycelium of Pleurotus ostreatus in vivo on mice, bearing melanoma B16-F0-GFP (2005) (5)
The Advantages of Using Fluorescent Proteins for In Vivo Imaging (2017) (5)
The cancer-inhibitory effects of proliferating tumor-residing fibroblasts (2021) (5)
High-metastatic triple-negative breast-cancer variants selected in vivo become chemoresistant in vitro (2017) (5)
Combination of Trabectedin With Oxaliplatinum and 5-Fluorouracil Arrests a Primary Colorectal Cancer in a Patient-derived Orthotopic Xenograft Mouse Model (2019) (4)
Sutureless Surgical Orthotopic Implantation Technique of Primary and Metastatic Cancer in the Liver of Mouse Models (2020) (4)
Potential of immunotherapy for sarcoma (2017) (4)
Whole-body subcellular multicolor imaging (2007) (4)
Fluorescence Molecular Targeting of Colon Cancer to Visualize the Invisible (2022) (4)
Clinical Correlation of the Histoculture Drug Response Assay in Gastrointestinal Cancer. (2018) (4)
Expression of prostate-specific antigen in human prostate specimens in in vitro three-dimensional histoculture (1993) (4)
Shedding (killer) light on tumors. (2012) (4)
Regarding the applications of fusion-fluorescence imaging using indocyanine green in laparoscopic hepatectomy. (2017) (4)
A review of tumor-specific fluorescence-guided surgery for colorectal cancer. (2020) (4)
Rapid tumor‐labeling kinetics with a site‐specific near‐infrared anti‐CEA nanobody in a patient‐derived orthotopic xenograft mouse model of colon cancer (2021) (4)
Is the Hoffman Effect for Methionine Overuse Analogous to the Warburg Effect for Glucose Overuse in Cancer? (2019) (4)
Comparison of label-free and GFP multiphoton imaging of hair follicle-associated pluripotent (HAP) stem cells in mouse whiskers (2015) (4)
Abstract 4167: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop to drive pancreatic cancer growth, metastasis and therapy resistance (2012) (4)
In vitro histoculture of human tumors with fluorescent dye end-points measured by confocal microscopy: high correlation of in vitro and in vivo chemosensitivity. (1992) (4)
Osteosarcoma of the Breast in a Patient Derived Orthotopic Xenograft (PDOX) Mouse Model Is Arrested by both Cisplatinum and Eribulin (2021) (4)
Eribulin Inhibits Osteosarcoma in a Clinically-accurate Bone-tumor-insertion PDOX Mouse Model (2021) (4)
In silico-designed mutations increase variable new-antigen receptor single-domain antibodies for VEGF165 neutralization (2018) (4)
Andrographolide, a diterpene lactone from the Traditional Chinese Medicine Andrographis paniculate, induces senescence in human lung adenocarcinoma via p53/p21 and Skp2/p27. (2022) (4)
Neddylation Regulates Macrophages and Implications for Cancer Therapy (2021) (4)
Comparison of in vitro invasiveness of high- and low-metastatic triple-negative human breast cancer visualized by color-coded imaging (2017) (4)
Tumor-targeting Salmonella typhimurium A1-R Inhibits Osteosarcoma Angiogenesis in the In Vivo Gelfoam® Assay Visualized by Color-coded Imaging. (2018) (4)
GFP labeling kinetics of triple-negative human breast cancer by a killer-reporter adenovirus in 3D Gelfoam® histoculture (2017) (4)
Cryopreservation of Hair-Follicle Associated Pluripotent (HAP) Stem Cells Maintains Differentiation and Hair-Growth Potential. (2016) (4)
Safety and Toxicity of Recombinant Methioninase and Polyethylene Glycol (PEG) Recombinant Methioninase in Primates. (2019) (4)
Dual-color imaging of tumor angiogenesis. (2009) (4)
Doxazosin-to-terazosin switch for benign prostatic hyperplasia. (1999) (4)
Methionine Restriction and Life-Span Extension. (2019) (4)
The Use of Fluorescent Anti-CEA Antibodies to Label, Resect and Treat Cancers: A Review (2021) (4)
Enzymatic assay for total plasma Cys (2008) (4)
Fluorescent Anti-MUC5AC Brightly Targets Pancreatic Cancer in a Patient-derived Orthotopic Xenograft (2021) (4)
Orthotopic Mouse Models of Tumor Metastasis Expressing Fluorescent Reporters Produce Imageable Circulating Tumor Cells (2014) (4)
Unchecked DNA synthesis and blocked cell division induced by methionine deprivation in a human prostate cancer cell line (1993) (4)
Model of Pancreatic Cancer Imaging and Magnetic Resonance Imaging on an Orthotopic High Correlation of Whole-Body Red Fluorescent Protein (2005) (4)
PHOTOCHEMICAL TECHNIQUE. III. QUARTZ CAPILLARY ARC LAMPS OF BISMUTH, CADMIUM, LEAD, MERCURY, THALLIUM AND ZINC (1932) (4)
Lack of influence of c-Ha-ras expression on the drug sensitivity of human bladder cancer histocultured in three-dimensions. (1993) (4)
Five‐day water‐only fasting decreased metabolic‐syndrome risk factors and increased anti‐aging biomarkers without toxicity in a clinical trial of normal‐weight individuals (2021) (4)
Long-Term Extensive Ectopic Hair Growth on the Spinal Cord of Mice from Transplanted Whisker Follicles (2015) (4)
Recruitment of Cancer-Associated Fibroblasts and Blood Vessels by Orthotopic Liver Tumors Imaged in Red Fluorescent Protein (RFP) Transgenic Nude Mice. (2015) (4)
In vivo growth patterns of human lung tumors in three-dimensional histoculture (1991) (4)
Immune reactions in skin and hair follicle gene therapy. (2003) (4)
Analysis of Anticancer Activity and Chemical Sensitization Effects of Dendropanax morbifera and Commersonia bartramia Extracts (2018) (3)
Efficacy of a Cell-Cycle Decoying Killer Adenovirus on 3-D Gelfoam®-Histoculture and Tumor-Sphere Models of Chemo-Resistant Stomach Carcinomatosis Visualized by FUCCI Imaging (2016) (3)
Constitutive behavior of methionyl-tRNA synthetase compared to repressible behavior of methionine adenosyltransferase in mammalian cells. (1981) (3)
Visualization of Metastasis in Orthotopic Mouse Models with Green Fluorescent Protein (1999) (3)
In Vivo-Like Growth Patterns of Multiple Types of Tumors in Gelfoam® Histoculture. (2018) (3)
Prospective Clinical Correlation of the Histoculture Drug Response Assay for Ovarian Cancer. (2018) (3)
The clinical benefit of the histoculture drug response assay. (2000) (3)
Nestin-Expressing Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Promote Whisker Sensory-Nerve Growth in Long-Term 3D-Gelfoam® Histoculture. (2016) (3)
Watching real-time metastasis in vivo. (2002) (3)
Afterword: Oral Methioninase-Answer to Cancer and Fountain of Youth? (2019) (3)
Abstract 4311: Fluorescence-guided surgery of pancreatic cancer using activatable cell penetrating peptides (ACPPs) in orthotopic mouse models (2014) (3)
Hyperthermia generated by magnetic nanoparticles for effective treatment of disseminated peritoneal cancer in an orthotopic nude-mouse model (2021) (3)
Eribulin Regresses a Doxorubicin-resistant Dedifferentiated Liposarcoma in a Patient-derived Orthotopic Xenograft Mouse Model (2020) (3)
A Non-invasive Imageable GFP-expressing Mouse Model of Orthotopic Human Bladder Cancer (2020) (3)
Differential Organ-targeting and Cellular Characteristics of Metastatic Human Pancreatic Cancer Cell Lines in Mouse Models. (2018) (3)
The Mucin Family of Proteins: Candidates as Potential Biomarkers for Colon Cancer (2023) (3)
The linkage of methionine addiction, overmethylation of histone H3 lysines and malignancy demonstrated when cancer cells revert to methionine-independence (2020) (3)
Orthotopic Metastatic Mouse Models of Prostate Cancer (2008) (3)
Osimertinib regressed an EGFR-mutant lung-adenocarcinoma bone-metastasis mouse model and increased long-term survival (2020) (3)
The future of tumour-specific fluorescence-guided surgery for pancreatic cancer. (2020) (3)
Laparoscopic Fluorescence Imaging for Identification and Resection of Pancreatic and Hepatobiliary Cancer (2013) (3)
Methioninase Cell-Cycle Trap Cancer Chemotherapy. (2019) (3)
Histone H3 lysine-trimethylation markers are decreased by recombinant methioninase and increased by methotrexate at concentrations which inhibit methionine-addicted osteosarcoma cell proliferation (2021) (3)
Abstract 2677: Determination of the optimal route of administration ofSalmonella typhimuriumA1-R to target breast cancer in nude mice (2012) (3)
Noninvasive imaging for evaluation of the systemic delivery of capsid‐modified adenovirus in an orthotopic model of advanced lung cancer (2007) (3)
In vivo cellular imaging using fluorescent proteins : methods and protocols (2012) (3)
Fluorophore-conjugated Helicobacter pylori recombinant membrane protein (HopQ) labels primary colon cancer and metastases in orthotopic mouse models by binding CEA-related cell adhesion molecules (2020) (3)
Real-time Non-invasive Spectral Imaging of Orthotopic Red Fluorescent Protein-expressing Lung Tumor Growth in Nude Mice. (2015) (3)
Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation (2022) (3)
Introduction to Hair-Follicle-Associated Pluripotent Stem Cells. (2016) (3)
Multikinase-Inhibitor Screening in Drug-resistant Osteosarcoma Patient-derived Orthotopic Xenograft Mouse Models Identifies the Clinical Potential of Regorafenib (2021) (3)
Clinically accurate orthotopic mouse models of cancer. (2001) (3)
Evaluation of an Enzymatic Method to Measure Total Homocysteine in Plasma (2002) (3)
TRAF6 regulates the signaling pathway influencing colorectal cancer function through ubiquitination mechanisms (2022) (3)
Development of New Spontaneous Metastatic Heterotopic Model of Lewis Lung Carcinoma Imaged by GFP Expression (2011) (3)
Fluorescence-guided Surgery with Splenic Preservation Prevents Tumor Recurrence in an Orthotopic Nude-mouse Model of Human Pancreatic Cancer. (2018) (3)
Color‐Coded Imaging of Breast Cancer Metastatic Niche Formation in Nude Mice (2015) (3)
Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model. (2019) (3)
Overexpressed NEDD8 as a potential therapeutic target in esophageal squamous cell carcinoma (2021) (3)
Ligation Method to Specifically Label a Liver Segment With Indocyanine Green in an Orthotopic Nude-Mouse Liver-Metastasis Model (2020) (3)
Therapeutic targeting of tumors with imageable GFP-expressing Salmonella typhimurium auxotrophic mutants (2008) (3)
Small Animal Whole-Body Optical Imaging Based on Genetically Engineered Probes (2008) (3)
Recombinant Methioninase Combined With Tumor-targeting Salmonella typhimurium A1-R Induced Regression in a PDOX Mouse Model of Doxorubicin-resistant Dedifferentiated Liposarcoma (2020) (3)
Crystal structure of L-methionine-lyase from Pseudomonas (2007) (3)
Toward Curative Fluorescence-Guided Surgery of Pancreatic Cancer. (2015) (3)
Anti-mucin 4 fluorescent antibody brightly targets colon cancer in patient-derived orthotopic xenograft mouse models: A proof-of-concept study for future clinical applications. (2022) (3)
Abstract 5547: Oral delivery of tumor-targetingSalmonella typhimuriumA1-R is effective therapeutically (2012) (2)
Tail spontaneous metastatic mouse model: comparison of metastatic potential of orthotopic and heterotopic models imaged by GFP and RFP protein. (2011) (2)
Chronic spinal cord injury functionally repaired by direct implantation of encapsulated hair-follicle-associated pluripotent (HAP) stem cells in a mouse model: Potential for clinical regenerative medicine (2022) (2)
Efficacy of YAP1-gene Knockdown to Inhibit Alveolar-Epithelial-Cell Senescence and Alleviate Idiopathic Pulmonary Fibrosis (IPF). (2021) (2)
3-Deazaadenosine, a stabilizer of whole-blood homocysteine content, does not interfere with the single-enzyme homocysteine assay while totally inhibiting the enzyme conversion homocysteine immunoassay. (2004) (2)
Modified Liver Hanging Maneuver for En-bloc Right-sided Hepatectomy Combined with Total Caudate Lobectomy for Colon-Cancer Liver Metastasis and Hepatocellular Carcinoma. (2016) (2)
Cancer, Methionine, and Transmethylation (1986) (2)
Histone H3K4me3 and H3K9me3 are super over-methylated in soft tissue sarcoma compared to normal muscle in patient-derived xenograft (PDX) mouse models: an indicator of cancer methionine addiction (2021) (2)
A Universal Gelfoam 3-D Histoculture Method to Establish Patient-derived Cancer Cells (3D-PDCC) Without Fibroblasts from Patient-derived Xenografts (2020) (2)
Hair-follicle-associated pluripotent (HAP) stem cells (2016) (2)
Angiotensin II type I receptor blocker, Losartan, inhibits fibrosis in liver by suppressing TGF-beta1 production (2016) (2)
Use of αv Integrin Linked to Green Fluorescent Protein in Osteosarcoma Cells and Confocal Microscopy to Image Molecular Dynamics During Lung Metastasis in Nude Mice. (2016) (2)
3D Sponge-Matrix Histoculture (2018) (2)
Targeting antibodies to live tumor tissue in 3-D histoculture (1992) (2)
Orthotopic Implantation of Intact Tumor Tissue Leads to Metastasis of OCUM-2MD3 Human Gastric Cancer in Nude Mice Visualized in Real Time by Intravital Fluorescence Imaging. (2016) (2)
A Gemcitabine Plus 5-Fluorouracil Combination Inhibits Gastric-Cancer Liver Metastasis in a PDOX Model: A Novel Treatment Strategy (2020) (2)
Abstract 2678: Traditional Chinese Medicine (TCM) in combination withS. typhimuriumA1-R for cancer treatment (2012) (2)
Orthotopic mouse models expressing fluorescent proteins for cancer drug discovery (2010) (2)
Green fluorescent protein: new light to visualize metastasis and angiogenesis in cancer (1999) (2)
Abstract 712: Salmonella typhimurium A1-R inhibits surgically induced breast cancer metastasis (2014) (2)
Abstract 547: A function-blocking monoclonal antibody directed against the collagen-binding α2integrin subunit inhibits primary tumor growth and metastasis in a fluorescent orthotopic mouse model of pancreatic cancer (2011) (2)
Lentivirus-based DsRed-2-transfected pancreatic cancer cells for deep in vivo imaging of metastatic disease. (2012) (2)
Sensitive assay of tumor S-adenosyl-methionine and S-adenosyl-homocysteine (2005) (2)
Methionine Dependency Determination of Human Patient Tumors in Gelfoam® Histoculture. (2018) (2)
Survival efficacy of adjuvant cytosine analog CS-682 treatment of human pancreatic cancer in an orthotopic metastatic model monitored by fluorescence whole-body imaging (2004) (2)
Efficacy of the Combination of a PARP Inhibitor and UVC on Cancer Cells as Imaged by Focus Formation by the DNA Repair-related Protein 53BP1 Linked to Green Fluorescent Protein. (2016) (2)
Fluorescent Anti-CEA Nanobody for Rapid Tumor-Targeting and Imaging in Mouse Models of Pancreatic Cancer (2022) (2)
Vascular Normalization by Antiangiogenic Agents Time-Course Imaging of Therapeutic Functional Tumor (2011) (2)
Human Hair Follicle Associated-Pluripotent (hHAP) Stem Cells Differentiate to Cardiac Muscle Cells. (2019) (2)
Hair Growth and Hair Follicle Cell Proliferation in Histocultured Mouse Skin (1991) (2)
Abstract 4750: Real-time imaging of 3-dimensional cancer cell movement in tissues (2011) (2)
Clinical Usefulness of the Histoculture Drug Response Assay for Prostate Cancer and Benign Prostate Hypertrophy (BPH). (2018) (2)
Imaging Nuclear-Cytoplasmic Dynamics in Primary and Metastatic Colon Cancer in Nude Mice. (2016) (2)
Salmonella typhimurium A1-R and Cell-Cycle Decoy Therapy of Cancer. (2016) (2)
Subcellular imaging of cancer cells in live mice. (2007) (2)
Real‐Time Fluorescence Imaging of the DNA Damage Repair Response During Mitosis (2015) (2)
Exosome Transfer Between Pancreatic-cancer Cells Is Associated With Metastasis in a Nude-mouse Model (2021) (2)
Abstract 4563: Monotherapy with a tumor-targeting mutant ofSalmonella typhimuriuminhibits human glioma in an orthotopic model in nude mice (2012) (2)
The use of transgenic fluorescent mouse strains, fluorescent protein coding vectors, and innovative imaging techniques in the life sciences (2008) (2)
Real-time in vivo cellular imaging of graft-versus-host disease and its reaction to immunomodulatory reagents. (2012) (2)
Efficacy of Methionine-Restricted Diets on Cancers In Vivo. (2019) (2)
metastatic mouse models of human prostate cancer cures orthotopicSalmonella typhimuriumMonotherapy with a tumor-targeting mutant of (2007) (2)
Glucose consumption end point in primary histoculture indicates recovery of human tumors from drug treatment (1992) (2)
Fluorescent angiogenesis models using gelfoam® implanted in transgenic mice expressing fluorescent proteins. (2014) (2)
Unique Benefits of Tumor-Specific Nanobodies for Fluorescence Guided Surgery (2021) (2)
Effective Tumor Targeting by EphA2-Agonist-Biotin-Streptavidin Conjugates (2021) (2)
Oral 5-FU is a more effective antimetastatic agent than UFT. (2004) (2)
Immuno-hyperthermia effected by antibody-conjugated nanoparticles selectively targets and eradicates individual cancer cells (2021) (2)
Antitumor activity of (2''R)-4'-O-tetrahydropyranyl adriamycin on human gastric cancer cell lines in vitro and in vivo. (1994) (2)
Methylation of intact chromosomes by bacterial methylases in agarose plugs suitable for pulsed-field electrophoresis. Methylation of intact chromosomes in agarose by methylases. (1990) (2)
Imageable clinically relevant mouse models of metastasis. (2014) (2)
Salmonella Typhimurium Mutants Selected to Grow Only in Tumors to Eradicate Them in Nude Mouse Models (2010) (2)
Disintegrin targeting of an αvβ3 integrin-over-expressing high-metastatic human osteosarcoma with echistatin inhibits cell proliferation, migration, invasion and adhesion in vitro (2016) (2)
Obesity Strongly Promotes Growth of Mouse MC38 Colon Cancer in an Orthotopic-syngeneic C57BL/6 Mouse Model (2022) (2)
Characterization of HCT 116 Human Colon Cancer Cells in an Orthotopic Model 1 (2008) (2)
Choline-deficient-diet Decreases Fibroblasts in the Circulating Tumor Cell (CTC) Microenvironment (2019) (2)
Development of the Histoculture Drug Response Assay (HDRA). (2018) (2)
In Vivo-Like Cell-Cycle Phase Distribution of Cancer Cells in Gelfoam® Histoculture Observed in Real Time by FUCCI Imaging. (2018) (2)
Dietary Methionine Restriction-Based Cancer Chemotherapy in Rodents. (2019) (2)
Hair Follicle Pluripotent Stem (hfPS) Cells (2009) (2)
High efficiency liposome-mediated transfection of the tyrosinase gene to cultured cells: A model for the gene therapy of hair color restoration (1994) (2)
Morphological and gene-expression characterization of viable heterogeneous circulating tumor cells size-captured and cultured from triple-negative breast cancer mouse models (2016) (2)
Dual-color fluorescence imaging of tumor/host interaction with green and red fluorescent proteins (2004) (2)
Color-Coded Imaging of Cancer and Stromal-Cell Interaction in the Pancreatic-Cancer Tumor Microenvironment (TME). (2021) (2)
Deletion of MTAP Highly Sensitizes Osteosarcoma Cells to Methionine Restriction With Recombinant Methioninase (2022) (1)
Cell Markers: Green Fluorescent Protein (2013) (1)
Traditional Chinese Medicine Xihuang Wan Inhibited Lewis Lung Carcinoma in a Syngeneic Model, Equivalent to Cytotoxic Chemotherapy, by Altering Multiple Signaling Pathways (2021) (1)
Development of a humanized anti-CEA antibody for fluorescent guided surgery of GI cancers (2019) (1)
Staging of metastatic pancreatic cancer in orthotopic mouse models by fluorescence laparoscopy is improved by an LED light source (2011) (1)
Mode of action of estra-1,3,5(10)-triene-3, 17 beta-diol, 3-benzoate, 17[4-[4-[bis(2-chloroethyl)amino]phenyl]-1-oxobutoxy] acetate] (KM2210) on MCF-7 human breast tumours transplanted into nude mice. (1993) (1)
Humanized Fluorescent Tumor-associated Glycoprotein-72 Antibody Selectively Labels Colon-cancer Liver Metastases in Orthotopic Mouse Models (2020) (1)
Histoculture radiometric in vitro hair growth assay (1993) (1)
Metastatic Pancreatic Cancer Staged By Fluorescence Laparoscopy In A Fluorescent Carcinomatosis Mouse Model (2011) (1)
Fluorescence-Guided Surgery of Human Colon Cancer Increases Disease-Free Survival in an Orthotopic Nude Mouse Model (2012) (1)
Is DNA methylation the new guardian of the genome? (2017) (1)
Parathyroid hormone-related protein expression in human pancreatic adenocarcinoma (2000) (1)
Abstract 5: Real-timein vivoimaging of osteosarcoma angiogenesis (2014) (1)
Targeted expression of GFP in the hair follicle using ex vivo viral transduction. (2008) (1)
Spectrally Distinct Double Labeling of Colon-Cancer Liver Metastases and Adjacent Liver Segment with a Near-Infrared-labeled Anti-Carcinoembryonic Antigen (CEA) Antibody and Indocyanine Green in an Orthotopic Mouse Model (2021) (1)
The Hair Follicle Stem Cell as the Paradigm Multipotent Adult Stem Cell (2008) (1)
Comparison of traditional Chinese medicine (TCM) herbal mixture LQ and paclitaxel on the phase of cancer cell cycle blockage and cancer cell invasion. (2013) (1)
Total Methionine Restriction Treatment of Cancer. (2019) (1)
Proof of concept of improved fluorescence-guided surgery of colon cancer liver metastasis using color-coded imaging of a tumor-labeling fluorescent antibody and indocyanine green restricted to the adjacent liver segment. (2022) (1)
CXC-Chemokines/CXCR2 mediate a novel pathway of angiogenesis in pancreatic cancer (2007) (1)
Imaging of Angiogenesis In Vivo with Fluorescent Proteins (2005) (1)
Abstract 1674: Significant reduction of primary growth and metastases through combined CXCR4 and HER-2 inhibition in an esophageal carcinoma orthotopic model (2011) (1)
Methods for rapid extraction of high‐quality RNA from FFPE cancer tissue (1048.14) (2014) (1)
Peripheral blood monocyte migration in lung transplant recipients. (1993) (1)
Green fluorescent protein for metastasis research. (2001) (1)
Protocols for Gelfoam(®) Histoculture of Hair-Shaft-Producing Mouse Whisker Follicles Containing Nestin-GFP-Expressing Hair-Follicle-Associated Pluripotent (HAP) Stem Cells for Long Time Periods. (2016) (1)
Protocols for Efficient Differentiation of Hair Follicle-Associated Pluripotent (HAP) Stem Cells to Beating Cardiac Muscle Cells. (2016) (1)
Imaging the role of the tumor microenvironment in tumor progression and metastasis (2016) (1)
Abstract A41: Cancer cells invade or divide, not both (2013) (1)
Pro-senescence neddylation inhibitor combined with a senescence activated β-galactosidase prodrug to selectively target cancer cells (2022) (1)
Non-invasively Imageable Tibia-tumor-fragment Implantation Experimental-bone-metastasis Mouse Model of GFP-expressing Prostate Cancer (2022) (1)
Abstract 1218: Telomerase-specific GFP-expressing adenovirus enables fluorescence-guided surgery (FGS) for patient-derived orthotopic xenograft (PDOX) in nude mice (2014) (1)
Combination of Trabectedin With Irinotecan, Leucovorin and 5-Fluorouracil Arrests Primary Colorectal Cancer in an Imageable Patient-derived Orthotopic Xenograft Mouse Model (2019) (1)
Abstract 1441: Use of RFP and GFP transgenic nude mice to study the tumor microenvironment of liver metastasis (2010) (1)
Prostate Cancer Metastasis Precursor Cells Contributes to Anoikis Resistance of Circulating Human Increased Expression of Apoptosis Inhibitor Protein XIAP (2005) (1)
Abstract 4306: Bioconjugation of near infrared dyes by PEGylation improves pharmacokinetics and allows for better labeling and imaging of human gastrointestinal cancers (2014) (1)
Abstract 5208: Simultaneous color-coded imaging to distinguish colon cancer stem-like and non-stem cells in the same tumor (2011) (1)
Subcellular imaging in vivo: the next GFP revolution. (2012) (1)
Correction: Involvement of CXCR4 Chemokine Receptor in Metastastic HER2-Positive Esophageal Cancer (2013) (1)
Abstract 101: Surgical orthotopic implantation (SOI) lung cancer model with 95% survival and 100% take rate for spectral imaging (2014) (1)
Abstract 4221: Imaging formation of the tumor microenvironment in orthotopic liver tumors in red fluorescent protein (RFP) transgenic nude mice (2016) (1)
Governing step of metastasis visualized in vitro (tumor colonizationylung canceryhost lungysponge-gel histocultureygreen f luorescent protein) (1997) (1)
Imaging enhancement of malignancy by cyclophosphamide: surprising chemotherapy opposite effects (2008) (1)
High Incidence of Lymph-node Metastasis in a Pancreatic-cancer Patient-derived Orthotopic Xenograft (PDOX) NOG-Mouse Model (2022) (1)
Methods for Tumor Targeting with Salmonella typhimurium A1-R. (2016) (1)
Linkage of Methionine Dependence and Other Features of Malignancy. (2019) (1)
Color-Coded Imaging of the Tumor Microenvironment (TME) in Human Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models. (2021) (1)
A Mouse Model of Fluorescent Protein-expressing Disseminated Peritoneal Lymphoma for Fluorescence-guided Surgery. (2016) (1)
Erratum: Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progession (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 24 (10920-10925) DOI: 10.1073/pnas.0914776107) (2010) (1)
Inhibition of pancreatic cancer-cell growth and metastasis in vivo by a pyrazole compound characterized as a cell-migration inhibitor by an in vitro chemotaxis assay. (2022) (1)
The chemical synthesis of high specific-activity [35S]adenosylhomocysteine. (1986) (1)
Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation (2022) (1)
Abstract 5530: Fluorescence laparoscopy improves metastatic detection in both early and advanced colon cancer (2012) (1)
Bevacizumab-IRDye800 Is an Effective Alternative to Anti-Carcinoembryonic Antigen (CEA) for Labeling Low CEA-Expressing Colorectal Tumors (2017) (1)
Clinical Usefulness of the Histoculture Drug Response Assay for Breast Cancer. (2018) (1)
In vivo fluorescence of medullary carcinoma of the thyroid: a technology with potential to improve visualization of malignant tissue at surgical resection. (2008) (1)
Creation of ultra-rare restriction sites in intact eucaryotic chromosomes mediated by bacterial methylases: an approach to sequencing and analyzing tumor and normal genomes. (1993) (1)
Subcellular real-time in vivo imaging of intralymphatic and intravascular cancer-cell trafficking (2008) (1)
Fluorescence-guided surgery: it is the cure that matters: in reply to Giorgakis and colleagues. (2015) (1)
Circulating tumour cells go green (2014) (1)
Hair-Shaft Growth in Gelfoam® Histoculture of Skin and Isolated Hair Follicles. (2018) (1)
193 Topical liposome targeting of melanin and dyes to the hair follicle in human studies (1997) (1)
Interstitial lung disease in an adult with Fanconi anemia: clues to the pathogenesis. (1997) (1)
Abstract 1695: Imaging of the interaction of pancreatic cancer and stellate cells during liver metastasis (2012) (1)
Nestin expression in hair follicle stem cells (2002) (1)
Recombinant Methioninase as a DNA Demethylation Agent. (2019) (1)
A Novel Orthotopic Mouse Model of Lung Metastasis Using Fluorescent Patient-derived Osteosarcoma Cells (2021) (1)
Noninvasive imaging in vivo with fluorescent proteins from centimeters to micrometers (2008) (1)
Taking chemotherapy from random to rational with the histoculture drug response assay. (1997) (1)
Near-Infrared Tumor-Specific Fluorescence Imaging of Pancreatic Cancer in Orthotopic Mouse Models Using the Da-Vinci Firefly Imaging System (2017) (1)
A real-time fluorescent model of human pancreatic cancer growth, progression, and metastases in the nude mouse (2000) (1)
Fluorophore-conjugated antibodies improve surgical resection of pancreatic cancer leading to prolonged disease-free survival and overall survival in orthotopic mouse models (2012) (1)
Abstract 1690: Tumor-educated macrophages promote tumor growth and peritoneal metastasis in an orthotopic nude mouse model of human pancreatic cancer (2012) (1)
Angiomouse: Imageable Models of Angiogenesis (2007) (1)
Drug exposure in a metastatic human lung adenocarcinoma cell line gives rise to cells with differing adhesion, proliferation, and gene expression: Implications for cancer chemotherapy (2015) (1)
Abstract 5529: Fluorescence-guided navigation surgery for resection of human glioma in an orthotopic model in nude mice (2012) (1)
Specific in vivo labeling with GFP retroviruses, lentiviruses, and adenoviruses for imaging (2008) (1)
GFP-Expressing Metastatic-Cancer Mouse Models (2002) (1)
Abstract 5900: Transforming growth factor-beta (TGF-β) inhibitor modulates cancer stroma in a pancreatic cancer orthotopic mouse model (2017) (1)
Abstract 3983: Real-time imaging of human thyroid cancer progression in a fluorescent orthotopic nude mouse model (2010) (1)
Use of high-resolution fluorescence laparoscopy with fluorophore-conjugated tumor-specific antibodies for the detection of pancreatic cancer metastasis invisible with standard laparoscopy. (2012) (1)
A Patient-Derived Orthotopic Xenograft Model of Gastroesophageal-Junction Adenocarcinoma Translated to the Clinic by Tumor-Targeting Fluorescent Antibodies to Carcinoembryonic-Antigen-Related Cell-Adhesion Molecules (2021) (1)
Review: Precise sarcoma patient-derived orthotopic xenograft (PDOX) mouse models enable identification of novel effective combination therapies with the cyclin-dependent kinase inhibitor palbociclib: A strategy for clinical application (2022) (1)
Abstract A41: Patient-Derived Fluorescent Orthotopic Xenografts (PDOX™) models for personalized anti-metastatic cancer therapy and drug discovery (2014) (1)
Survival efficacy of adjuvant cytosine-analog CS-682 in a fluorescent orthotopic model of human pancreatic cancer. (2004) (1)
Why Patient-Derived Mouse Models Need to Be Orthotopic (2017) (1)
Use of αv Integrin Linked to GFP to Image Molecular Dynamics in Trafficking Cancer‐Cell Emboli (2017) (1)
In Memoriam: Jørgen Rygaard (1934–2016), Father of Patient-Derived Mouse Models of Cancer and Modern Cancer Research (2017) (1)
Dual color, in vivo imaging of gene expression in a pancreatic cancer model (2003) (1)
Stromal-cell and cancer-cell exosomes leading the metastatic exodus for the promised niche (2013) (1)
Comparison of in vitro invasiveness of high- and low-metastatic triple-negative human breast cancer visualized by color-coded imaging (2016) (1)
Monotherapy with a tumor-targeting mutant of S. typhimurium cures orthotopic metastatic mouse models of human prostate cancer (2007) (1)
Abstract 1445: Metastasis-resistant fatty liver induced by a choline-deficient diet (2018) (0)
GFP labeling kinetics of triple-negative human breast cancer by a killer-reporter adenovirus in 3D Gelfoam® histoculture (2017) (0)
ASSOCIATION FOR ACADEMIC SURGERY, 2004 Characterization of HCT116 Human Colon Cancer Cells in an Orthotopic Model 1 (2008) (0)
Abstract 2403: Imaging of UVB and UVC-induced DNA damage repair in cancer cells in Gelfoam histoculture and minimal cancer in mice (2014) (0)
Salmonella typhimurium A1-R Exquisitely Targets and Arrests a Matrix-producing Triple-negative Breast Carcinoma in a PDOX Model (2021) (0)
Abstract 437: Longitudinal imaging of the pancreatic cancer tumor microenvironment (2011) (0)
Dual-color imaging of tumor cell and nuclear shape changes during extravasation in living mice (2005) (0)
Abstract 5183: Raster-image-correlation spectroscopy of paxillin-GFP-expressing breast cancer cell in vitro and in vivo (2012) (0)
Abstract 2679: Color-coded selective chemotherapy of methioninase-synchronized S-phase cancer cells expressing cell-cycle-specific fluorescent reporters: A general approach to the treatment of cancer (2012) (0)
Abstract 1758: Cancer cell location in tumor determines cell cycle position and dormancy. (2013) (0)
IN THE SPOTLIGHT Bugging Tumors (2012) (0)
Abstract A92: Killing quiescent cancer cells in vitro and in vivo with tumor targetingSalmonella typhimuriumA1-R (2013) (0)
Hair follicle associated pluripotent (HAP) stem cells jump from transplanted whiskers to pelage follicles and stimulate hair growth (2022) (0)
2032 Recombinant methioninase (rMETase) as a novel radiation sensitizer (1999) (0)
Abstract 5112: Traditional Chinese medicine formula LQ inhibits spontaneous and cyclophosphamide-enhanced metastasis. (2013) (0)
Abstract 4128: Extensive morphological heterogeneity of circulating and selected high metastatic variants and differential chemosensitivity of human prostate cancer in mouse models (2015) (0)
Reversion of Cancer Cells From Methionine-Addiction to Methionine Independence Results in Loss of Histone Lysine Overmethylation and Malignancy (2021) (0)
Abstract 4375: UVC irradiation in combination with fluorescence-guided surgery cures metastatic human pancreatic cancer in orthotopic mouse models (2014) (0)
Abstract 1456: Efficacy of photo-immunotherapy in combination with surgical resection on a pancreatic cancer patient derived orthotopic xenograft (PDOX) (2015) (0)
W1827 Fluorophore-Conjugated Anti-CEA Antibody for Intraoperative Imaging of Pancreatic and Colorectal Cancer (2008) (0)
Title Metronomic gemcitabine in combination with sunitinib inhibits multisite metastasis and increases survival in an orthotopic model of pancreatic cancer (2015) (0)
1089 CHARACTERIZATION AND IMAGING OF CD133+ LIVER CANCER STEM CELLS (2013) (0)
Genetically altered Salmonella typhimurium profoundly increases survival in nude mice with metastatic PC-3 prostate tumors. (2006) (0)
Cyclophosphamide-induced renal damage in nude mice prevented by traditional Chinese medicine (TCM) herbal mixture LQ. (2013) (0)
Abstract 4903: Microarray gene expression analysis of human prostate cancer PC-3 cells targeted by Salmonella typhimurium A1-R (2015) (0)
Abstract 3110: Heterokaryon formation and nuclear fusion of hybridizing cancer cells visualized in real time by color-coded imaging (2018) (0)
A hand-held portable imaging system for effective fluorescence-guided surgery of a pancreatic patient-derived orthotopic xenograft (PDOX) in nude mice. (2014) (0)
Abstract 2688: Color-coded imaging of the pre-metastatic niche in the lung and liver indicates the involvement of cancer-associated fibroblasts (2012) (0)
A triple-negative matrix-producing breast carcinoma is arrested by tumor-targeting Salmonella typhimurium A1-R in a PDOX model (2021) (0)
Expression and Targeting of Tumor Markers in Gelfoam® Histoculture: Potential Individualized Assays for Immuno-Oncology. (2018) (0)
Abstract IA06: Patient-derived orthotopic xenografts (PDOX): Better mimic the patient than subcutaneous xenografts (2016) (0)
Highly Metastatic Chemoresistant Stem-like Cells Selected by Serial Passage of Human Pancreatic Cancer Cells in Orthotopic Mouse Models (2014) (0)
Histocultures and Organ Cultures (2001) (0)
Speaker Bio's and abstracts (2017) (0)
External optical imaging of freely moving mice with green fluorescent protein-expressing metastatic tumors (2000) (0)
Hair Follicle-Associated Pluripotent (HAP) Stem Cells in Gelfoam® Histoculture for Use in Spinal Cord Repair. (2018) (0)
Abstract 4336: Fluorescence laparoscopy for high-resolution pancreatic tumor imaging in an orthotopic mouse model (2010) (0)
Abstract 2680: Characterization of cultured circulating melanoma cells for individualized therapy (2012) (0)
Abstract 372: Disease-free survival and overall survival from colon cancer is improved with fluorescence-guided surgery in metastatic mouse models (2012) (0)
Real-Time Optical Imaging of Primary Tumor Growth and Multiple Metastatic Events in a Pancreatic Cancer Orthotopic Model 1 (2002) (0)
Peanut Agglutinin-Immobilized Fluorescent Nanospheres with Surface Poly(N-vinylacetamide) Chains as a Novel Colonoscopic Imaging Agent (2010) (0)
Hair-follicle-associated pluripotent stem cells derived from cryopreserved intact human hair follicles sustain multilineage differentiation potential (2019) (0)
Future Directions: The Known and Unknown Roles of Hair-Follicle Stem Cell Types (2010) (0)
Abstract 4220: Tumor-targeting Salmonella typhimurium A1-R efficacy on colon cancer liver metastasis alone and in combination with fluorescence-guided surgery (2016) (0)
Abstract 4280: Color-codedin vivoimaging of tumor stem cells and co-implanted non-stem cancer cells (2010) (0)
An Improved Encapsulation Method for Cryopreserving Hepatocytes for Functional Transplantation Using a Thermo-reversible Gelation Polymer (2020) (0)
Use of Patient-Derived Orthotopic Xenografts (PDOX) to Evaluate Transformative Cancer Therapeutics (2017) (0)
A novel alkylateing agent, glufosfamide, enhances activity of gemcitabine in models of pancreatic cancer (2006) (0)
Targeting neddylation inhibits intravascular survival and extravasation of cancer cells to prevent lung-cancer metastasis (2019) (0)
Abstract 1872: Fluorescence-guided surgery in the tumor microenvironment in a syngeneic mouse model of EL-4 lymphoma (2017) (0)
Direct implantation of hair-follicle-associated pluripotent (HAP) stem cells repairs intracerebral hemorrhage and reduces neuroinflammation in mouse model (2023) (0)
Abstract 580: Bone marrow cells trafficking afterSalmonella typhimuriumA1-R tumor targeting (2010) (0)
Real-time confocal imaging of trafficking of nestin-expressing multipotent stem cells in mouse whiskers in long-term 3-D histoculture (2012) (0)
Abstract 5182: Real-time molecular imaging of αv-integrin GFP-expression in osteosarcoma cellsin vitroandin vivo (2012) (0)
Abstract 386: Real-time noninvasive optical imaging of angiogenesis and vasculogenesis inhibition and normalization (2010) (0)
1394 Hair-follicle-associated pluripotent (HAP) stem cells captured on polyvinylidene fluoride membranes promote functional recovery of spinal cord injury (2018) (0)
Increased Metastasis in an Orthotopic Model-Bearing Colon Cancer Cells Display PIK 3 CA Mutant (2007) (0)
Dual-color imaging of tumor cell and nuclear deformation in the living animal (2005) (0)
Fluorescent antibody tagging of colon cancer in the nude mouse; a model for improved surgical accuracy in the oncologic patient. (2006) (0)
895 Isoproterenol directs human hair follicle-associated pluripotent (hHAP) stem cells to differentiate to cardiac muscle cells (2017) (0)
Determinative Structural Features Identified With Probe-based Confocal Endomicroscopy for the Accurate Diagnosis of Gallbladder Malignancy (2021) (0)
Abstract 2684: Imaging lung colony formation by osteosarcoma cells expressing αvintegrin-GFP in nude mice (2012) (0)
Imaging capillary migration of tumor cells in live animals (2005) (0)
Techniques for Surgical Orthotopic Implantation of Human Tumors to Immunodeficient Mice (2017) (0)
Abstract 466: Bone marrow and cancer cells mutually affect each other (2011) (0)
Abstract 579: Chinese herbal mixture LQ inhibits tumor growth and metastasis and increases survival in orthotopic and other mouse models of human and mouse cancer (2010) (0)
Abstract 2786: Color-coded fluorescence-guided surgery in a patient-derived orthotopic xenograft (PDOX) nude mouse model of colon-cancer liver metastasis with ICG and a fluorescent antibody (2020) (0)
Making Patient Tumors Glow in Nude Mice by Coloring the Stroma with Fluorescent Proteins (2012) (0)
Abstract 726: Fluorophore-conjugated antibodies improve surgical resection of pancreatic cancer leading to prolonged disease-free survival and overall survival in orthotopic mouse models. (2013) (0)
In vitro drug response assays for entry into the rational era cancer chemotherapy. (1995) (0)
Effect of adoptive T-cell therapy and intratumoral heat-killed bacteria on large tumors. (2014) (0)
Correction for Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progession (2010) (0)
Effect of specific targeting of a modified salmonella typhymurium on cancer metastases. (2010) (0)
Micro RNA miR-1303 Promotion of Proliferation, Migration and Invasion of Human Liver Cancer Cells Is Enhanced by Low Talin 1 (TLN1) Expression (2022) (0)
An improved optically imageable metastatic model of human colon cancer orthotopically implanted on the cecum (2005) (0)
Abstract B17: Stem-like cells selected by serial in vivo orthotopic passage of human pancreatic cancer cells (2014) (0)
Abstract 1458: Orthotopic imageable peritoneal carcinomatosis GFP nude mouse model of human esophageal cancer (2010) (0)
Abstract 1757: Gelfoam® histoculture enables cancer cells to mimicin vivocell cycle behavior. (2013) (0)
Abstract 2019: Photoimmunotherapy with an anti-EGFR antibody conjugated to an IRDye700 results in extensive and rapid cell death in vitro and in vivo in human pancreatic cancer cell lines (2015) (0)
Abstract 1356: Real-timein vivocolor-coded imaging of the interaction between immunocytes and tumor cells during cancer therapy (2010) (0)
Cancer Therapy : Preclinical A Genetically Engineered Oncolytic Adenovirus Decoys and Lethally Traps Quiescent Cancer Stem – like Cells in S / G 2 / M Phases (2013) (0)
From Hair to Heart: Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Can Simultaneously Differentiate Into Mature Cardiomyocytes and Atrial Myocytes (2021) (0)
Novel reconstruction using tumor-containing autologous bone grafts frozen in liquid nitrogen. (2010) (0)
Abstract 2804: Anti-tumor and anti-metastatic efficacy of TCM on prostate cancer in orthotopic model of metastatic cancer. (2013) (0)
Effect of methionine-depletion via methioninase-treatment on cancer cells in S/G2 phase and chemosensitivity. (2015) (0)
Abstract 1230: Efficacy of Salmonella typhimurium A1-R and anti-VEGF therapy on a patient-derived orthotopic xenograft (PDOX) pancreatic cancer model (2014) (0)
Abstract 4312: Seamless fluorescence guided surgery for pancreatic cancer is facilitated by a hand held electrocautery pencil with excitation light source (2014) (0)
152d: FLUORESCENT MUCIN 5AC ANTIBODY BRIGHTLY LABELS COLONIC POLYPS CONTAINING INTRAMUCOSAL ADENOCARCINOMA IN CPC-APC MICE: TECHNOLOGY FOR IMPROVED COLONOSCOPY (2022) (0)
Abstract 3437: GFP imaging of angiogenesis in lymph node metastasis (2010) (0)
Targeting of primary lung metastasis of high-grade osteosarcoma in nude mice with a modified strain of Salmonella typhymurium (2008) (0)
Abstract 4583: Comparison of repeated minor liver resection and major resection on lung metastasis growth in mice (2012) (0)
Specific Targeting and Labeling of Colonic Polyps in CPC-APC Mice with Mucin 5AC Fluorescent Antibodies: A Model for Detection of Early Colon Cancer (2023) (0)
The role of nestin-expressing cells during whisker sensory-nerves extention in long-term 3D cultureand in vivo (2016) (0)
Abstract 1385: Real-time imaging of paxillin-GFP expression in breast cancer cells in vitro and in vivo (2011) (0)
Abstract 4151: Real-time imaging of inter-cellular communication via exosomes (2012) (0)
Abstract 500: Efficacy of UVC irradiation on GFP-expressing melanoma growth and vascularity in the ear of nude mice (2010) (0)
Fluorescence Imaging of Tumors in Human Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models (2017) (0)
Abstract 4201: Development of a syngeneic metastatic mouse model of malignant lymphoma (2015) (0)
Abstract 4232: GFP imaging of DNA repair after UV irradiation of cancer cells (2012) (0)
Multipotent nestin-expressing hair follicle stem cells HAIR FOLLICLE (2009) (0)
IS6. Biomarker * Developmental Therapeutics (2012) (0)
Abstract 5533: Imaging stromal recruitment during liver metastasis formation in the GFP-MUP-uPA mouse (2012) (0)
21 Non-invasive single-photon and multi-photon imaging of stem cells and cancer cells in mouse models (2018) (0)
Abstract 3733: Development of photoimmunotherapy for colon cancer in nude mice models (2019) (0)
Abstract 710: The efficacy of tumor-targeting Salmonella typhimurium A1-R on bone metastasis (2014) (0)
Imaging the Governing Step of Metastasis in Gelfoam® Histoculture. (2018) (0)
Hair-follicle-associated pluripotent (HAP) stem cells differentiate into mature beating cardiomyocyte sheets on flexible substrates in vitro (2022) (0)
Color-coded double labeling of colon-cancer liver metastasis and the adjacent liver segment with a tumor-specific fluorescent antibody and indocyanine green (2022) (0)
Is Methioninase Useful for the Prevention of Hyperhomocysteinemia-Associated Cardiovascular Disease? (1997) (0)
Chemotherapy of methioninase-synchronized S/G2 phase-blocked cancer cells identified by cell cycle-specific fluorescent reporters. (2012) (0)
Inhibition of soft-tissue sarcoma lung metastasis by tumor-targeting Salmonella typhimurium A1-R. (2015) (0)
The effect of PEGylation on the enzyme kinetics of recombinant methioninase (2006) (0)
Abstract 5279: Imaging of pancreatic cancer with activated cell penetrating peptide dendrimers (2011) (0)
Fluorescence-guided surgery for primary and metastatic bone tumors in orthotopic nude mouse models (2020) (0)
Abstract 3412: Imaging of methioninase-induced S/G2-phase-trapping for subsequent effective chemotherapy. (2013) (0)
Synergy of oral recombinant methioninase (rMETase) and 5-fluorouracil on poorly differentiated gastric cancer. (2022) (0)
Abstract 366: Enhanced tumor detection of fluoroscence laparoscopy improves laparoscopic resection of primary pancreatic cancer in mouse models (2012) (0)
Abstract 3385: A craniectomy open window model for longitudinal subcellular imaging of cancer cell nuclear-cytoplasmic dynamics in the brain (2010) (0)
Spontaneous and cyclophosphamide-enhanced metastasis inhibited by traditional Chinese medicine (TCM) herbal mixture LQ. (2013) (0)
Abstract 3388: Selective GFP labeling of disseminated cancer with a telomerase-specific adenovirus (OBP-401) to report recurrence after resection (2010) (0)
Abstract 2802:Salmonella typhimuriumA1-R inhibits brain metastasis in an orthotropic breast cancer nude-mouse model. (2013) (0)
Oncogenes and Methionine Addiction of Cancer: Role of c-MYC (2023) (0)
Precise surgery of in the lung in mouse models enabled by in situ fluorescence labelling with a adenovirus. (2015) (0)
Abstract 4138: Fluorescence laparoscopy with an LED light source enables fluorescence-guided resection of pancreatic cancer, labeled with fluorophore-conjugated antibodies, in mouse models. (2013) (0)
Diagnosis of early colorectal cancer using lectin-immobilized fluorescent nanospheres (2010) (0)
Abstract 1658: Anti-CEACAM binding protein for fluorescence visualization of primary colon cancer in patient-derived orthotopic xenograph mouse models (2020) (0)
Color-coded labeling of colon cancer liver metastasis and adjacent liver segment for image guided metastasectomy: a proof of concept review of clinical translatability (2022) (0)
Patient-derived orthotopic xenograft models for osteosarcoma individualized precision treatment and effective drug discovery (2020) (0)
Methioninase Gene Therapy. (2019) (0)
Bile-duct obstruction model imaged at the single-cell level (2005) (0)
Abstract 1691: A primer dose followed by low-bolus dose schedule of tumor-targeting ofS. typhimuriumA1-R is effective for tumor-targeted therapy (2012) (0)
Abstract 3130: Zoledronic acid inhibits proliferation and metastasis of human pancreatic cancer in the patient-derived orthotopic xenograft (PDOX) model by targeting tumor-educated macrophages (2014) (0)
Abstract 2442: A precise orthotopic rectal tumor model for evaluating therapeutic response of cancer treatment (2012) (0)
Abstract 1769: Real-time imaging demonstrates cancer cells exposed to UV irradiation either repair their DNA or die. (2013) (0)
Abstract 375: Fluorescence-guided surgery leads to improved resection of primary pancreatic cancer and prolonged survival (2012) (0)
Reply to "Dual-color, whole-body imaging in mice" (2005) (0)
O2-9-2PANCREATIC CANCER PATIENT-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) CURED BY FLUORESCENCE-GUIDED SURGERY FOLLOWED BY UVC (2014) (0)
The Combination of Cisplatinum and Doxorubicin Regressed Primary Osteosarcoma of the Breast in a PDOX Mouse Model (2021) (0)
S4-6 Non-Invasive Visualization of Fluorescent Tumors In Intact Animals (2002) (0)
High-metastatic triple-negative breast-cancer variants selected in vivo become chemoresistant in vitro (2017) (0)
Abstract B60: FUCCI cell cycle imaging identifies drug-resistant quiescent cancer cells within tumors. (2013) (0)
Use of fluorescent proteins and color-coded imaging to visualize cancer cells with different genetic properties (2016) (0)
In Vitro Culture and Characterization of Human Lung Cancer Circulating Tumor Cells Isolated by Size Exclusion from an Orthotopic Nude-Mouse Model Expressing Fluorescent Protein (2014) (0)
Abstract 1694: Imaging cell cycle progression in gastric cancer lymph node metastasis indicates large fraction of proliferating cancer cells (2012) (0)
Abstract 1454: Telomerase-specific adenoviral labeling and treatment of hepatocellular carcinoma (2010) (0)
Abstract 4911: Aggressive variants isolated from human pancreatic cancer passaging in mice are enriched in stem cell markers and PEAK1 expression. (2013) (0)
Fluorophore-Conjugated Chimeric Anti-CEA Antibodies for Fluorescence-Guided Surgery of Gastrointestinal (GI) Tumors (2015) (0)
Abstract 13: Color-coded imaging of vessel anastomosisin vivousing RFP and CFP transgenic mice (2014) (0)
Abstract 1570: Novel strategy for eradicating lymph node metastasis of early-stage colorectal cancers using telomerase-dependent replicating adenoviral agent. (2013) (0)
Characterization of the nestin-driven-GFP (ND-GFP) nude mouse and its uses in cancer research (2005) (0)
Fluorescence imaging of angiogenesis in green fluorescent protein-expressing tumors (2002) (0)
Corrigendum (2015) (0)
Abstract 2380: Fluorescence labeling of human gastric cancer using novel tumor specific near infrared labeled antibodies (2023) (0)
Hair follicle associated pluripotent (HAP) stem cell from young mice have the greatest potential to differentiate to cardiac muscle cells (2017) (0)
Abstract 1638: Imaging the interaction of αvintegrin-GFP in osteosarcoma cells with RFP-expressing host stromal cells and tumor scaffold collagen in nude mice. (2013) (0)
Cancer Drives Metastatic Growth and Therapy Resistance in Pancreatic KRas Induces a Src / PEAK 1 / ErbB 2 Kinase Amplification Loop (2012) (0)
Determination of protein expression of lineage markers in cultured MDA-MB-435 cells. (2013) (0)
Dual-color imaging of nascent angiogenesis of pancreatic cancer in an orthotopic model (2006) (0)
Altered Methionine Metabolism and Unbalanced Transmethylation: A Possible Basis for the Dynamic Phenotype of Cancer (2018) (0)
of Uterine Cervical Cancers Cells with Cancer-Associated Fibroblasts to Support Progression HB-EGF and PDGF Mediate Reciprocal Interactions of Carcinoma (2011) (0)
Abstract 5176: Imaging αvintegrin-GFP during tumor blood vessel interaction in the chick CAM (2012) (0)
Abstract B13: Salmonella typhimurium A1-R targets human pancreatic cancer patient-derived orthotopic xenograft (PDOX) in nude mice. (2013) (0)
Abstract 728: Fluorescence-guided surgery for human-patient colon cancer tumorgrafts using a fluorophore-conjugated anti-CEA antibody. (2013) (0)
Abstract 5230: Development of a series of genetically fluorescent human osteosarcoma cell lines with increasing spontaneous metastatic capability (2011) (0)
Abstract 2384: Time-lapse imaging of response to DNA damage occuring during mitosis (2014) (0)
Evodiamine inhibits ESCC by inducing M-phase cell-cycle arrest via CUL4A/p53/p21 axis and activating noxa-dependent intrinsic and DR4-dependent extrinsic apoptosis. (2022) (0)
Abstract 514: A novel dual color mouse model for studying the tumor microenvironment of pancreatic adenocarcinoma (2011) (0)
Abstract 2689: Inhibition of metastasis of circulating tumor cells by extracellular matrix secreted by human embryonic cells (2012) (0)
Abstract 3951: Imaging exosome transfer from colon cancer cells to stroma at liver metastatic sites in nude mouse. (2013) (0)
Afterward: The Future of Patient-Derived Models of Cancer (2017) (0)
Abstract 5111: Protective effect of Traditional Chinese Medicine formula LQ against cyclophosphamide-induced renal damage in nude mice. (2013) (0)
Use of tumor-targeting salmonella typhimurium to eradicate human glioma in an orthotopic model in nude mice. (2012) (0)
Abstract 3486: Efficacy of neoadjuvant chemotherapy in combination with fluorescence-guided surgery on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) (2014) (0)
Abstract 4284: Combined magnetic resonance and fluorescence-protein imaging to simultaneously assess the anti-tumor and anti-angiogenesis efficacy of selenium (2011) (0)
Abstract 432: A tissue engineered human extra cellular matrix (hECM) inhibits tumor growth (2011) (0)
Abstract A40: Pancreatic cancer patient-derived orthotopic xenograft (PDOX™) is effectively targeted bySalmonella typhimuriumA1-R (2014) (0)
Abstract 1686: Low dose metronomic gemcitabine has high antimetastatic efficacy in an orthotopic mouse model of pancreatic cancer (2010) (0)
Fluorescent Protein-Expressing Transgenic Nude Mice as Hosts for Patient Tumors (2017) (0)
Imaging the Steps of Metastasis at the Macro and Cellular Level with Fluorescent Proteins in Real Time (2011) (0)
Abstract 1686: Effect of echistatin on proliferation, migration, invasion and angiogenesis of integrin αvβ3-expressing human osteosarcoma (2011) (0)
POTENTIAL OF NESTIN-EXPRESSION HAIR FOLLICLE CELLS TO FORM NEURONS AND BLOOD VESSELS (2004) (0)
Proof of Principle of Combining Fluorescence-Guided Surgery with Photoimmunotherapy to Improve the Outcome of Pancreatic Cancer Therapy in an Orthotopic Mouse Model (2022) (0)
Abstract 703: Caffeine modulates the cell cycle in cancer cells to enhance cisplatin efficacy. (2013) (0)
Abstract 1756: Intravital imaging of cancer cell cycle in the bone marrow. (2013) (0)
Effects of drugs on cellular dynamics visualized in live cells labeled with GFP in the nucleus and RFP in the cytoplasm (2005) (0)
Abstract 1315: Real-time imaging of nuclear-cytoplasmic dynamics in UV light killing of cancer cells expressing fluorescent proteins (2010) (0)
192 Transplanted hair follicles give rise to blood vessels in skin visualized in nestin-driven GFP mice (2004) (0)
Comparison of the Efficacy of EGFR Tyrosine Kinase Inhibitors Erlotinib and Low-dose Osimertinib on a PC-9-GFP EGFR Mutant Non-small-cell Lung Cancer Growing in the Brain of Nude Mice (2020) (0)
Abstract 2409: A precise orthotopic metastatic model of rectal cancer (2011) (0)
Cell-cycle fate-monitoring to identify individual chemosensitive and chemoresistant cancer cells in heterogeneous cancer populations. (2015) (0)
Effect of dormant cancer cells on angiogenesis after resisting chemotherapy. (2013) (0)
Abstract 711: Salmonella typhimurium A1-R induces quiescent FUCCI-expressing cancer cells to cycle and become chemosensitive (2014) (0)
Abstract 3375: In vivo passaging of primary pancreatic tumor enriches for stem cells and PEAK expression (2012) (0)
Fluorescence Lifetime Imaging Microcopy of Extravasating Cancer Cells in the Mouse Microenvironment (2012) (0)
Abstract 4111: Imaging of colon cancer-cell mitosis within liver metastasis in nude mice (2016) (0)
Abstract 1983: Real-time imaging of exosomes dynamic of cross-talking and cell trafficking in 3D Gelfoam® histoculture (2014) (0)
Abstract 1661: Temozolomide suppresses a doxorubicin resistant follicular dendritic cell sarcoma in a patient derived orthotopic xenograft mouse model (2020) (0)
Myc-driven lymphomas respond with both apoptosis and senescence to anticancer treatment in vivo (2001) (0)
Chapter 8 Hair Follicle Pluripotent Stem ( hfPS ) Cells (2009) (0)
Comparison of fluorescence-labeling strategies of colon cancer for fluorescence-guided surgery of liver metastasis in orthotopic mouse models (2020) (0)
Targeting Cancer with Amino-Acid Auxotroph Salmonella typhimurium A1-R (2012) (0)
Prevention of experimental human breast cancer bone metastasis in nude mice by tumor-targeting Salmonella typhimurium A1-R. (2015) (0)
Real-Time Multi-Color Sub-Cellular Imaging in Live Mice (2006) (0)
Effect of anti-β1 integrin antibody on lung seeding of osteosarcoma cells in live mice visualized by single-cell in vivo imaging. (2012) (0)
Multi-Color Imaging of In Vivo with Fluorescent Proteins: The New Cell Biology (2005) (0)
Chemotactic Enhancement by Lavaged Proteins (1988) (0)
Nestin-expressing multipotent hair follicle stem cells for regenerative medicine (2013) (0)
Optimization of Chimeric Anti-CEA Antibody Labeling with Visable and Near-Infrared Dyes for High Resolution Imaging of Pancreatic Cancer in Orthotopic Nude Mouse Models (2014) (0)
Abstract 5398: A primer dose followed by low-bolus dose schedule for safe and efficacious bacterial tumor targeting withS. typhimuriumA1-R (2011) (0)
Abstract 5553: Real-time imaging of αvintegrin-GFP expression in osteosarcoma cells trafficking in blood vessels of nude mice (2012) (0)
Publisher Correction: Is DNA methylation the new guardian of the genome? (2018) (0)
The role of RANK-signaling in breast cancer development and metastasis (2008) (0)
Effective targeting of the ubiquitin-like modifier NEDD8 for lung adenocarcinoma treatment (2020) (0)
598 Chimeric Antibodies to CEA Improve Detection of Human Colon Cancer in Orthotopic Mouse Models (2013) (0)
The Photolysis of β-Caryophyllene Nitrosite1 (1934) (0)
Abstract 2687: Imaging sub-cellular dynamics of proliferating intra- and extra-vascular cancer cells (2012) (0)
In vitro culturing of circulating tumor cells in lung cancer management (2012) (0)
Abstract 3009: Membrane pseudokinase PTK7 regulates metastasis (2014) (0)
The Revival of Patient-Derived Xenograft Mouse Models of Cancer: Way Back to the Future (2017) (0)
M1672 An Analysis of CD133 Positive Bone Marrow in Oval Cell Induced Model and a Role of CD133 Bone Marrow in Mice With Liver Fibrosis (2010) (0)
Abstract 2371: Comparison of repeated minor liver resection and major resection on lung metastasis growth in mice (2011) (0)
Front Matter: Volume 6868 (2008) (0)
From hair to heart: Nestin-expressing hair follicle associated pluripotent (HAP) stem cells differentiate to beating cardiac muscle cells (2016) (0)
Salmonella typhimurium A1-R prolongs survival of aggressive pancreatic cancer in orthotopic nude mouse models. (2013) (0)
Abstract 2681: Multicolor imageable orthotopic tumorgraft models of human patient pancreatic cancer (2012) (0)
Abstract 4313: Efficacy of fluorescence-guided surgery on primary human osteosarcoma (2014) (0)
O1-13-5REAL TIME COLOR CODED IMAGING OF CELL CYCLE PHASE DEMONSTRATES WHY INVASIVE METASTATIC CANCER CELLS ARE DRUG RESISTANT (2014) (0)
Trafficking of nestin-expressing cells within the mouse whisker in 3D Gelfoam® histoculture imaged in real time with confocal microscopy (2013) (0)
Abstract 1982: Invading cancer cells are mostly in G0/G1 and resist chemotherapy demonstrated by real-time FUCCI imaging of cell-cycle kinetics in Gelfoam® histoculture (2014) (0)
Whisker follicles transplanted to the spine of nude mice for spinal cord repair generate extensive ectopic hair growth (2016) (0)
Abstract 1143: The circulating tumor cell (CTC) microenvironment visualized by color coded imaging (2019) (0)
Neural potential of stem cells in the hair follicle (2005) (0)
Abstract 1641: Color-coded imaging of interaction between RFP-expressing blood vessels and αvintegrin-GFP expressing osteosarcoma cells. (2013) (0)
Altered Regulation of Transmethylation and Loss of Organotypic Behavior in Cancer (1991) (0)
52 Attenuated immunogenicity and toxicity of PEGylated recombinant methioninase (PEG-rMETase) in primates (2004) (0)
Abstract 1229: The advantages of patient-derived orthotopic xenograft (PDOX) of metastatic cervical cancer for individualized therapy compared to the PDX model (2014) (0)
Abstract 1754: Dormant cancer cells are resistant to conventional therapies and induce tumor vessels after chemotherapy. (2013) (0)
Imaging cellular dynamics in vivo with multicolor fluorescent proteins (2005) (0)
Abstract 4281: Real-time imaging of the cell-cycle in vivo (2011) (0)
Nestin-expressing stem cells form the whisker sensory nerve in 3D Gelfoam® histoculture (2013) (0)
Abstract 1148: Recombinant cancer-stromal cells Identified in the metastatic tumor microenvironment By color-coded imaging (2019) (0)
Subcellular imaging tracks cancer cells in mice (2006) (0)
RE: "Intraoperative Near-infrared Imaging Can Identify Neoplasms and Aid in Real-time Margin Assessment During Pancreatic Resection". (2019) (0)
Abstract 1412: Two-photon imaging of cancer cell extravasation in live mice (2011) (0)
Abstract 438: The CFP nude mouse as a host for color-coded imaging of the tumor microenvironment (2011) (0)
Abstract 4960: Serial in vivo orthotopic passage of human pancreatic cancer cells selects for increased stem cell-like behavior (2014) (0)
P5-02-05: Real-Time Subcellular Imaging of Breast Cancer Cell Attachment in Blood Vessels Using GFP-Labeled Paxillin in Live Mice. (2011) (0)
Fluorescent Proteins as Sensors for Cellular Behavior in Mice. (2018) (0)
TRAF6 regulates the abundance of RIPK1 and inhibits the RIPK1/RIPK3/MLKL necroptosis signaling pathway and affects the progression of colorectal cancer (2023) (0)
Abstract 5114: Multi-organ metastatic capability of 4T1 mammary carcinoma cells after surgical resection of primary orthotopic tumor. (2013) (0)
Abstract 1294: Inhibition of angiogenesis in lymph node metastasis (2010) (0)
Tri-color imaging of the interaction between GFP host macrophages and lymphocytes with human HT-1080 GFP-RFP tumor cells in live GFP-transgenic immunocompetent mice (2006) (0)
Beating Heart Cells from Hair-Follicle-Associated Pluripotent (HAP) Stem Cells. (2018) (0)
Ischemia reperfusion-induced metastasis is resistant to PPARγ agonist pioglitazone in a murine model of colon cancer (2020) (0)
Identification of tumor-specific promoters of Salmonella Typhimurium. (2007) (0)
Abstract 1539: Tumor-educated macrophages promote proliferation of human pancreatic cancer cellsin vitroandin vivo. (2013) (0)
Growth of doxorubicin-resistant undifferentiated spindle-cell sarcoma PDOX is arrested metabolic targeting with recombinant methioninase † Running title : Recombinant methioninase arrests a doxorubicin-resistant spindle-cell sarcoma (2017) (0)
CAOCER, METHIONINE, AID 'IRANSMElHYIATION (1986) (0)
Abstract 709: Efficacy of Salmonella typhimurium A1-R on experimental breast cancer brain metastasis (2014) (0)
Abstract 1314: Real-time imaging of individual cancer cell nuclear-cytoplasmic dynamics of UV-induced apoptosis of cancer cells in the brain (2010) (0)
Comparison of "Dimensionality" of Cancer Cell Culture in Gelfoam® Histoculture and Matrigel. (2018) (0)
Abstract 219: Fluorescence-guided surgery with an anti-CA 19-9-conjugated fluorophore in combination with neoadjuvant chemotherapy inhibits metastatic recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) nude mouse model (2015) (0)
Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Encapsulated on Polyvinylidene Fluoride Membranes (PFM) Promote Functional Recovery from Spinal Cord Injury (2018) (0)
Abstract 2874: Inhibition of tumor angiogenesis bySalmonella typhimuriumA1-R in thein vivoGelfoam color-coded imaging assay (2017) (0)
Marked efficacy of the novel camptothecin MEN4901/T-0128 in orthotopic and metastatic human tumor xenograft models (2006) (0)
Abstract 1204: Establishment of a patient-derived orthotopic xenograft (PDOX) model of patient cervical cancer (2014) (0)
P2-11-2EFFICACY OF TUMOR-TARGETING SALMONELLA TYPHIMURIUM A1-R ON HIGHLY METASTATIC HUMAN PANCREATIC CANCER IN NUDE MICE (2014) (0)
Effect of genistein and genistein analogs on growth of human prostate tissue in vitro. (1999) (0)
Abstract 588: Effect of antibiotic treatment onSalmonella typhimuriumA1-R tumor targeting of prostate cancer (2010) (0)
Rational design and physiological selection of a RAF pathway inhibitor that disrupts angiogenesis and tumor growth (2008) (0)
Abstract 5552: Macrophages increase brain metastasis in a chick embryo model (2012) (0)
Abstract 5546: UVC irradiation inhibits superficial tumor growth in the brain of nude mice (2012) (0)
Sa1215 - Majority of Patients with Gastrointestinal Amyloidosis have Upper Gut Mucosal Involvement on Biopsy and Improve with Small Bowel Bacterial Overgrowth Treatment (2018) (0)
Abstract 5323: Staging of metastatic pancreatic cancer is facilitated by fluorescence laparoscopy (2011) (0)
Abstract 1632: Anti-β1 integrin antibody inhibits osteosarcoma lung seeding and metastasis (2011) (0)
Abstract LB-507: A color coded fluorescent transgenic mouse model of spontaneous pancreatic cancer for imaging spectrally distinct cancer cells and stroma (2012) (0)
148. Fluorescent LYVE1 Antibody for Visualization of Real Time Intralymphatic Tumor Cell Trafficking (2008) (0)
List of contributors (2020) (0)
Human hair-follicle associated pluripotent (HAP) stem cells differentiate to cardiac muscle cells (2017) (0)
Novel mouse glioma model: cell-type and region specific activation of oncogenes using lentiviral vectors (2008) (0)
Abstract 1408: Tumor-targeting Salmonella typhimurium A1-R promotes CD8+ T cell infiltration in pancreatic cancer in an orthotopic syngeneic mouse model (2016) (0)
Abstract 4025: Combination strategy of endoscopic resection and telomerase-targeting oncolytic virus for eradicating lymph node metastasis of submucosal invasive colorectal cancer (2014) (0)
Indocyanine Green Fluorescence Image-guided Laparoscopic Hepatectomy Enabled Resection of a Tumor Invisible With Ultrasonography (2021) (0)
Total-Homocysteine Enzymatic Assay, Yuying Tan, Li (2000) (0)
The First Mouse Model of Meckel’s Diverticulum Carcinoma (2022) (0)
Abstract 1980: Fusion of cancer and stromal cells imaged by color -coded imaging of metasasis (2017) (0)
Diagnosis and Pathological Analysis of Patient Cancers by Detection of Proliferating Cells in Gelfoam® Histoculture. (2018) (0)
Abstract 2686: Methioninase S-phase block of cancer cells imaged in real time by cell-cycle-specific fluorescence reporters (2012) (0)
Cover Image, Volume 118, Number 1, January 2017 (2017) (0)
Histoculture radiometric in vitro hair growth assay. (1993) (0)
New platinum complex compounds with reduced nephrotoxicity discovered in long-term histoculture of human renal cortical tissue. (1995) (0)
Are CTCs metastatic precursors (2012) (0)
Abstract 3: Imaging of stromal cells during hepatocellular metastasis formation in the RFP-MUP-uPA mouse (2014) (0)
Abstract 5123:In vitroculture for characterization of circulating GFP-expressing tumor cells in orthotopic lung cancer models . (2013) (0)
Abstract 731:In vivofluorescence labeling of gastrointestinal stromal tumor (GIST) . (2013) (0)
Multicolor fluorescence imaging of subcellular dynamics of cancer cells in live mice (2006) (0)
Abstract 369: Tumor detection and surgical navigation with fluorescence laparoscopy is enhanced with combinations of differently labeled fluorophore-conjugated antibodies and fluorescent proteins (2012) (0)
Abstract 1755: Invasive cancer cells are mostly in the G0/G1phase of the cell cycle. (2013) (0)
Guanylate-binding Protein 2 Expression Is Associated With Poor Survival and Malignancy in Clear-cell Renal Cell Carcinoma (2022) (0)
Abstract 5123: Curative fluorescence-guided surgery of pancreatic cancer in combination with UVC irradiation in orthotopic mouse models (2015) (0)
Imaging tumor angiogenesis with fluorescent proteins (2004) (0)
Multicolor Imaging with Fluorescent Proteins in Mice (2010) (0)
4.03 – Fluorescent Proteins (2014) (0)
Abstract 3729: Tumor-specific antibody labeling of pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model using a fluorescent humanized anti-CEA antibody (2017) (0)
ASO Visual Abstract: Proof of Principle of Combining Fluorescence-Guided Surgery with Photoimmunotherapy to Improve the Outcome of Pancreatic Cancer Therapy in an Orthotopic Mouse Model (2022) (0)
Cervical Cancer PDOX Models (2017) (0)
Abstract 2265: Sub-fractions of conditioned medium, from hypoxia-induced cells with multipotent potential, exhibit a significant anti-oncogenic activity (2014) (0)
Chapter 2 3 D Sponge-Matrix Histoculture : An Overview (0)
Abstract 2685: Imaging the various mechanisms of cancer-cell killing bySalmonella typhimuriumA1-R (2012) (0)
Imageable orthothopic metastatic mouse models for the identification of the antitumor and antimetastatic efficacy of traditional Chinese medicine (TCM). (2012) (0)
Abstract 702: Chinese Medicine formulation LQ inhibits FUCCI-expressing HeLa cells at the G0/G1phase in 2D and 3D culture and invasion with Gelfoam®3D culture. (2013) (0)
Abstract B01: A portable imaging system for fluorescence-guided surgery on a human colon cancer patient-derived orthotopic xenograft (PDOX™) nude mouse model (2014) (0)
High-Resolution Magnetic Resonance Imaging of the Efficacy of the Cytosine Analogue 1-[2-C-Cyano-2-deoxy- -D-arabino-pentofuranosyl]-N-palmitoyl Cytosine (CS-682) in a Liver-Metastasis Athymic Nude Mouse Model (2003) (0)
Rapid isolation of imageable circulating tumor cells. (2011) (0)
Abstract A40: Cancer cells form in vivo-like tumors in Gelfoam histoculture (2013) (0)
Abstract 216: Pancreatic cancer fluorescence-guided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA) improves surgical resection and increases disease-free and overall survival in orthotopic mouse models (2015) (0)
The First Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Cancer: Cancer of the Colon, Pancreas, Lung, Breast, Ovary, and Mesothelioma (2017) (0)
343 Salmonella typhimurium A1-R effectively targets experimental breast cancer brain metastasis (2014) (0)
Abstract 3317: Efficacy ofSalmonella typhimuriumA1-R treatment on human patient pancreatic tumorgrafts. (2013) (0)
Abstract 4282: Real-time subcellular imaging of cancer cell nuclear dynamics in the brain of live mice (2011) (0)
Abstract 3071: Size-based isolation of circulating tumor cells (CTCs) in mouse tumor models (2014) (0)
Determining the metastatic potential of circulating tumor cells. (2012) (0)
A mouse model of rectal cancer that mimics the clinical disease. (2011) (0)
Efficacy of a genetically modified Salmonella typhymurium against metastatic osteosarcoma in an orthotopic mouse model. (2016) (0)
Abstract 704: Comparison of Salmonella typhimurium A1-R and VNP20009 on the Lewis Lung carcinoma (2014) (0)
Imaging capillary tumor-cell migration, deformation and extravasation in live mice (2005) (0)
376 Tumor-targeting Salmonella typhimurium A1-R enhances gemcitabine–bevacizumab efficacy on a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model (2014) (0)
657 Expression of the stem cell associated and intermediate filament protein nestin during organogenesis of the prostate (2012) (0)
Efficacy of the combination of fluorescence-guided surgery and adjuvant therapy in orthotopic nude mouse models of cancer (2020) (0)
Imaging DNA Repair After UV Irradiation Damage of Cancer Cells in Gelfoam® Histoculture. (2018) (0)
Precision medicine for recalcitrant cancers with the patient-derived orthotopic xenograft (PDOX) mouse models for identification of effective therapy. (2017) (0)
New Approaches to Cancer Therapy Using in vivo Fluorescent-Protein Imaging (2019) (0)
Abstract 1390: In vivo tracking of cancer-cell-derived exosomes (2012) (0)
Abstract 710: Telomerase-specific oncolytic adenovirus OBP-301 kills quiescent peritonially disseminated cancer cells. (2013) (0)
Fluorescence-guided tumor resection using a telomerase-dependent adenoviral GFP for cancer-specific labeling. (2010) (0)
Methionine dependence in cancer cells — A review (2007) (0)
Preclinical fluorescent mouse models of pancreatic cancer (2007) (0)
Abstract 2676: A secreted tissue engineered extracellular matrix (shECM) prevents recurrence in post-resection pancreatic cancer models (2012) (0)
The measurement of glucose consumption in histoculture to determine effects of doxorubicin and cisplatinum on human gastric carcinoma. (1993) (0)
Abstract 3957: Cardiac metastasis in mice with primary breast carcinoma. (2013) (0)
Tumor-Educated Macrophages Stimulate Tumor Progression in an Orthotopic Human Pancreatic Cancer Nude Mouse Model (2012) (0)
Abstract 419: A comparison between the OV100 and Maestro fluorescence imaging systems for noninvasive detection of metastasis. (2013) (0)
Abstract 3319:Salmonella typhimuriumA1-R inhibits aggressive pancreatic tumor growth and prolongs survival. (2013) (0)
Abstract 585:Salmonella typhimuriumA1-R targets quiescent cancer cells. (2013) (0)
Human cancer growth in the nude mice model is associated with impaired metabolism of the methionine cycle (2008) (0)
Induced fluorescence of breast cancer in the mouse model: A simple technology to improve visualization of malignant tissue during breast cancer surgery. (2016) (0)
Abstract 729: Chimeric antibodies to tumor antigen CEA improve detection of human colon cancer for fluorescence-guided surgery. (2013) (0)
S2008 CXC-Chemokine/CXCR2 Biological Axis Promotes Angiogenesis In Vitro and In Vivo in Pancreatic Cancer (2009) (0)
Effect of fluorescence-guided surgery followed by UVC on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) in nude mice. (2014) (0)
Effect of Salmonella typhimurium A1-R on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) in nude mice. (2014) (0)
Abstract PR14: Real-time in-vivo image-guided cell-cycle perturbation to increase tumor chemosensitivity (2016) (0)
Hair-follicle Topical Targeting of Liposome-entrapped Melanin, Genes and Proteins(第300回北里医学会招待学術講演会要旨) (1998) (0)
Abstract 597: Bacteria targeting and tumor vascular destruction byS. typhimuriumA1-R depend on the vascularity of the tumor site (2010) (0)
Abstract 722: Evaluation of a chimeric anti CEA-conjugated antibody with AlexaFlour or Dylight fluorescent dyes for imaging pancreatic cancer in orthotopic nude mouse models. (2013) (0)
Nerve Growth and Interaction in Gelfoam® Histoculture: A Nervous System Organoid. (2018) (0)
Crystal Structure of L-methionine alpha-, gamma-lyase (2004) (0)
Abstract 2791: mTOR inhibitor and VEGFR inhibitor combination therapy regress a doxorubicin resistant osteosarcoma in a patient-derived orthotopic xenograft model andin vivoangiogenesis assay model (2020) (0)
P2-11-1FLUORESCENCE-GUIDED SURGERY OF PANCREATIC PATIENT-DERIVED ORTHOTOPIC XENOGRAFT(PDOX) WITH A PORTABLE IMAGING SYSTEM (2014) (0)
Development of fluorescence-guided surgery for colorectal cancer in orthotopic mouse models using fluorescent tumor-specific antibodies to increase survival (2020) (0)
Final technical report, August 15, 1971--August 14, 1972 (1972) (0)
Breast-tumor-targeted therapy with a Salmonella typhimurium LEU-ARG auxotroph (2006) (0)
Abstract LB-263: Analysis of microenvironment effects on pancreatic cancer biomarker expression using a novel method for FFPE RNA extraction (2016) (0)
Publisher Correction: Is DNA methylation the new guardian of the genome? (2018) (0)
Multi-color imaging of angiogenesis of orthotopic human tumors in the nestin-driven GFP nude mouse (2005) (0)
Molecular surgery using a novel biological agent, OBP-301, for lymph node micrometastasis in human colorectal cancer. (2014) (0)
Abstract 5095: Real-time FUCCI imaging of cell cycle phase in tumors demonstrates why cancer chemotherapy is not effective in solid cancers (2014) (0)
Fluorescence-guided surgery using patient-derived orthotopic xenograft models of cancer (2020) (0)
Serial In Vivo Passaging of Human Pancreatic Tumors in Nude Mice Results in Aggressive Variants Enriched in Stem Cell Markers and PEAK1 Expression (2013) (0)
269 Selective in vivo therapeutic targeting of prostate cancer with a specific double-amino-acid auxotroph of Salmonella typhimurium (2004) (0)
Salmonella typhimurium A1-R targets chemoresistant stem-like human pancreatic cancer cells. (2013) (0)
The Use of Patient-Derived Orthotopic Xenograft (PDOX) Models to Develop Curative Fluorescence-Guided Surgery of Cancer (2017) (0)
Discovery of HAP Stem Cells. (2016) (0)
Long-chain Non-coding RNA MIR4435-2HG Expression Correlates With Size of Intestinal Polyps in Children and With Metastasis of Colon Cancer (2022) (0)
The relationship between tumor size and chemosensitivity of murine bladder cancer. (1994) (0)
Abstract 3306: Traditional Chinese Medicine (TCM) enhances efficacy and reduces toxicity of tumor-targetingS. typhimuriumA1-R in a syngeneic breast cancer metastatic mouse model. (2013) (0)
Abstract 5177: Molecular targeting of αvβ3integrin by echistatin inhibits tumor progression and metastasis in osteosarcoma (2012) (0)
Abstract 2322: Knockdown of the beta 1 integrin subunit inhibits tumor growth and metastasis in an orthotopic mouse model of pancreatic cancer (2010) (0)
Corrigendum to Cancer cells mimic in vivo spatial-temporal cell-cycle phase distribution and chemosensitivity in 3-dimensional Gelfoam® histoculture but not 2-dimensional culture as visualized with real-time FUCCI imaging (Cell Cycle, 14, 6 (808-819), 10.1080/15384101.2014.1000685) (2015) (0)
Novel Cardiac Biopsy Scoring Tool to Predict Clinical Outcomes in Cardiac Light Chain (AL) Amyloidosis (2017) (0)
Eradication of soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model by tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin. (2016) (0)
Effect of major liver resection on colon cancer metastasis in the lung and liver. (2012) (0)
Synergy of Patient-Derived Orthotopic Xenografts (PDOX) Models and Molecular Profiling for Optimal Therapy (2017) (0)
Protocols for Ectopic Hair Growth from Transplanted Whisker Follicles on the Spinal Cord of Mice. (2016) (0)
In Memoriam: Joseph Leighton, 1921-1999-Father of 3-Dimensional Tissue Culture. (2018) (0)
Abstract B171: Traditional Chinese medicine (TCM) herbal mixture LQ targets lung cancer metastasis. (2013) (0)
Fluorophore-conjugated antibodies for imaging and resection of GI tumors (2016) (0)
Effect of salmonella typhimurium A1-R on quiescent cancer cells that do not respond to standard chemotherapy. (2013) (0)
Lung metastasis targeting by a tumor-killing Salmonella typhimurium mutant. (2010) (0)
Abstract 3896: Alteration of malignancy and histone-H3 lysine-methylation status in osteosarcoma cells which acquire methotrexate resistance in vitro (2023) (0)
Abstract 877: Efficacy ofSalmonella typhimuriumA1-R on chemoresistant stem-like human pancreatic cancer cells. (2013) (0)
Abstract 3311:In vivoselection of S.typhimuriumA1-R enhanced tumor-targeting variants. (2013) (0)
Crystallization and preliminary crystallographic characterization of recombinant L-methionine-alpha-deamino-gamma-mercaptomethane lyase (methioninase). (2000) (0)
Hair-follicle associated pluripotent (HAP) stem cells differentiate to beating cardiac tissue sheets (2016) (0)
Induced fluorescence of medullary carcinoma of the thyroid: A technology with potential to improve visualization of malignant tissue at the time of surgical resection. (2016) (0)
Abstract 1975: Real-time FUCCI imaging demonstrates targeting dormant cancer cells (2014) (0)
Abstract 4110: Color-coded imaging of the tumor microenvironment of malignant lymphoma in a syngeneic mouse model (2016) (0)
Precise recurrence-free fluorescence-guided surgery with color-coded cancer and stromal cells in a patient-derived orthotopic xenograft model of pancreatic cancer (2020) (0)
Abstract 849: Detection of circulating micrometastasis in pancreatic cancer patients by immunomagnetic nanoparticles combined with RT-PCR (2010) (0)
Anti-inflammatory and Anti-thrombotic Efficacy of Targeted Ultrasound Microbubbles on LPS-induced HUVEC Cells (2021) (0)
Abstract 4027: Traditional Chinese Medicine herbal mixture LQ prevents cyclophosphamide-induced metastasis and toxicity (2014) (0)
Crystal Structure of Homocysteine alpha-, gamma-lyase at 1.8 Angstroms (2004) (0)
Abstract 1979: Three-dimensional Gelfoam® histoculture enables cancer cells to mimicin vivocancer cell cycling as visualized with FUCCI imaging (2014) (0)
Synergy of Combining Methionine Restriction and Chemotherapy: The Disruptive Next Generation of Cancer Treatment (2023) (0)
Color‐coded chemotherapy: S/G2‐phase‐trapping by methioninase pre‐treatment, indicated by FUCCI imaging, enables highly effective cancer chemotherapy (923.11) (2014) (0)
Abstract 583: Treatment of human liver cancer in nude mice with a tumor-targetingSalmonella typhimuriumauxotroph (2010) (0)
Fluorescence-guided surgery improved long-term survival in orthotopic nude mouse models of cancer (2020) (0)
Oral Installation of Recombinant Methioninase-producing Escherichia coli into the Microbiome Inhibits Colon-cancer Growth in a Syngeneic Mouse Model (2022) (0)
Salmonella typhimurium A1-R effectively targets human-patient pancreatic tumorgrafts in nude mice. (2013) (0)
Abstract 4300: Selective GFP labeling of cancer with a telomerase-specific adenovirus (OBP-401) to report future recurrence after resection (2011) (0)
Patient-Like Orthotopic Metastatic Models of Human Cancer (2004) (0)
292 Salmonella typhimurium A1-R decoys quiescent cancer cells to cycle rendering them chemosensitive (2014) (0)

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What Schools Are Affiliated With Robert M Hoffman?

Robert M Hoffman is affiliated with the following schools: