Robin Allshire
#122,140
Most Influential Person Now
Scientist
Robin Allshire's AcademicInfluence.com Rankings
Robin Allshirebiology Degrees
Biology
#8560
World Rank
#11657
Historical Rank
Cell Biology
#557
World Rank
#570
Historical Rank
Genetics
#1045
World Rank
#1143
Historical Rank
Molecular Biology
#1751
World Rank
#1780
Historical Rank
Download Badge
Biology
Robin Allshire's Degrees
- PhD Genetics University of Oxford
Why Is Robin Allshire Influential?
(Suggest an Edit or Addition)According to Wikipedia, Robin Campbell Allshire is Professor of Chromosome Biology at University of Edinburgh and a Wellcome Trust Principal Research Fellow. His research group at the Wellcome Trust Centre for Cell Biology focuses on the epigenetic mechanisms governing the assembly of specialised domains of chromatin and their transmission through cell division.
Robin Allshire's Published Works
Published Works
- Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain (2001) (2852)
- Telomere reduction in human colorectal carcinoma and with ageing (1990) (1660)
- RNAi-mediated chromatin silencing in fission yeast. (2008) (1015)
- Requirement of Heterochromatin for Cohesion at Centromeres (2001) (636)
- Methylation of Histone H4 Lysine 20 Controls Recruitment of Crb2 to Sites of DNA Damage (2004) (595)
- Epigenetic regulation of centromeric chromatin: old dogs, new tricks? (2008) (554)
- Regulation of telomere length and function by a Myb-domain protein in fission yeast (1997) (513)
- The case for epigenetic effects on centromere identity and function. (1997) (477)
- Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation. (1995) (475)
- Comparative Functional Genomics of the Fission Yeasts (2011) (439)
- Ten principles of heterochromatin formation and function (2017) (412)
- Transient Inhibition of Histone Deacetylation Alters the Structural and Functional Imprint at Fission Yeast Centromeres (1997) (384)
- Human telomeres contain at least three types of G-rich repeat distributed non-randomly. (1989) (376)
- RNA interference is required for normal centromere function infission yeast (2004) (354)
- Position effect variegation at fission yeast centromeres (1994) (336)
- Hairpin RNAs and Retrotransposon LTRs Effect RNAi and Chromatin-Based Gene Silencing (2003) (333)
- The chromodomain protein Swi6: a key component at fission yeast centromeres (1995) (312)
- Heterochromatin and RNAi Are Required to Establish CENP-A Chromatin at Centromeres (2008) (276)
- Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function. (1996) (260)
- Distinct protein interaction domains and protein spreading in a complex centromere. (2000) (260)
- RNA silencing and genome regulation. (2005) (259)
- Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe (1998) (258)
- Dimerisation of a chromo shadow domain and distinctions from the chromodomain as revealed by structural analysis (2000) (253)
- Human telomeres: fusion and interstitial sites. (1989) (242)
- RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing. (2005) (241)
- Stc1: A Critical Link between RNAi and Chromatin Modification Required for Heterochromatin Integrity (2010) (209)
- Methylation: lost in hydroxylation? (2005) (206)
- Restricted epigenetic inheritance of H3K9 methylation (2015) (203)
- Fission Yeast Scm3: A CENP-A Receptor Required for Integrity of Subkinetochore Chromatin (2009) (202)
- Telomere‐associated chromosome breakage in fission yeast results in variegated expression of adjacent genes. (1994) (184)
- Novel functional requirements for non‐homologous DNA end joining in Schizosaccharomyces pombe (2001) (183)
- Extensive telomere repeat arrays in mouse are hypervariable. (1990) (180)
- cis-Acting DNA from Fission Yeast Centromeres Mediates Histone H3 Methylation and Recruitment of Silencing Factors and Cohesin to an Ectopic Site (2002) (174)
- Telomeric repeat from T. thermophila cross hybridizes with human telomeres (1988) (168)
- The role of heterochromatin in centromere function (2005) (163)
- Localization of the 26S proteasome during mitosis and meiosis in fission yeast (1998) (158)
- Synthetic Heterochromatin Bypasses RNAi and Centromeric Repeats to Establish Functional Centromeres (2009) (158)
- Quantitative single-molecule microscopy reveals that CENP-ACnp1 deposition occurs during G2 in fission yeast (2012) (155)
- Kinetochore and heterochromatin domains of the fission yeast centromere (2004) (151)
- Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe. (2015) (146)
- Common Ancestry of the CENP-A Chaperones Scm3 and HJURP (2009) (143)
- Cloning of human telomeres by complementation in yeast (1989) (141)
- Centromere Silencing and Function in Fission Yeast Is Governed by the Amino Terminus of Histone H3 (2003) (140)
- A histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice (2014) (132)
- Identification of Noncoding Transcripts from within CENP-A Chromatin at Fission Yeast Centromeres* (2011) (129)
- Sim4: a novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation. (2003) (128)
- Splicing Factors Facilitate RNAi-Directed Silencing in Fission Yeast (2008) (124)
- Live analysis of lagging chromosomes during anaphase and their effect on spindle elongation rate in fission yeast. (2000) (115)
- Hsk1–Dfp1 is required for heterochromatin-mediated cohesion at centromeres (2003) (112)
- Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications. (2002) (109)
- RNA-directed transcriptional gene silencing in mammals. (2005) (106)
- Centromeres: getting a grip of chromosomes. (2000) (105)
- Fission yeast mutants that alleviate transcriptional silencing in centromeric flanking repeats and disrupt chromosome segregation. (1999) (103)
- Stretching it: putting the CEN(P-A) in centromere. (2003) (103)
- A NASP (N1/N2)-Related Protein, Sim3, Binds CENP-A and Is Required for Its Deposition at Fission Yeast Centromeres (2007) (103)
- The Kinetochore Proteins Pcs1 and Mde4 and Heterochromatin Are Required to Prevent Merotelic Orientation (2007) (99)
- The Chromatin-Remodeling Factor FACT Contributes to Centromeric Heterochromatin Independently of RNAi (2007) (96)
- A role for DNA polymerase α in epigenetic control of transcriptional silencing in fission yeast (2001) (95)
- The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin (2007) (94)
- The domain structure of centromeres is conserved from fission yeast to humans. (2001) (92)
- Plasticity of Fission Yeast CENP-A Chromatin Driven by Relative Levels of Histone H3 and H4 (2007) (91)
- Sequence Features and Transcriptional Stalling within Centromere DNA Promote Establishment of CENP-A Chromatin (2015) (90)
- Fission yeast genes which disrupt mitotic chromosome segregation when overexpressed. (1996) (82)
- Factors That Promote H3 Chromatin Integrity during Transcription Prevent Promiscuous Deposition of CENP-ACnp1 in Fission Yeast (2012) (82)
- Long non-coding RNA-mediated transcriptional interference of a permease gene confers drug tolerance in fission yeast (2014) (81)
- Gain of function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions (2018) (80)
- RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription (2005) (79)
- The Schizosaccharomyces pombe HIRA-Like Protein Hip1 Is Required for the Periodic Expression of Histone Genes and Contributes to the Function of Complex Centromeres (2004) (78)
- Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA (2009) (78)
- Common ground: small RNA programming and chromatin modifications. (2011) (77)
- The Schizosaccharomyces pombe hst4(+) gene is a SIR2 homologue with silencing and centromeric functions. (1999) (74)
- Centromeres, checkpoints and chromatid cohesion. (1997) (73)
- Those interfering little RNAs! Silencing and eliminating chromatin. (2004) (70)
- SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation (2020) (70)
- Centromeres become unstuck without heterochromatin. (2002) (68)
- Hairpin RNA induces secondary small interfering RNA synthesis and silencing in trans in fission yeast (2010) (68)
- RNAi and Heterochromatin--a Hushed-Up Affair (2002) (67)
- Distinct roles for Sir2 and RNAi in centromeric heterochromatin nucleation, spreading and maintenance (2013) (63)
- Analysis of chromatin in fission yeast. (2004) (61)
- Building centromeres: home sweet home or a nomadic existence? (2010) (61)
- CENP-A confers a reduction in height on octameric nucleosomes (2013) (51)
- The pad1 + Gene Encodes a Subunit of the 26 S Proteasome in Fission Yeast* (1998) (50)
- A fission yeast chromosome can replicate autonomously in mouse cells (1987) (50)
- A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin (2015) (48)
- Genome-Wide Studies of Histone Demethylation Catalysed by the Fission Yeast Homologues of Mammalian LSD1 (2007) (47)
- A New Role for the Transcriptional Corepressor SIN3; Regulation of Centromeres (2003) (44)
- Epigenetic gene silencing by heterochromatin primes fungal resistance (2019) (42)
- The Mal2p Protein Is an Essential Component of the Fission Yeast Centromere (2002) (42)
- Emerging Properties and Functional Consequences of Noncoding Transcription (2017) (41)
- Eic1 links Mis18 with the CCAN/Mis6/Ctf19 complex to promote CENP-A assembly (2014) (38)
- Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant (2013) (38)
- Schizosaccharomyces pombe Git7p, a Member of the Saccharomyces cerevisiae Sgt1p Family, Is Required for Glucose and Cyclic AMP Signaling, Cell Wall Integrity, and Septation (2002) (37)
- A role for DNA polymerase alpha in epigenetic control of transcriptional silencing in fission yeast. (2001) (37)
- Centromere DNA Destabilizes H3 Nucleosomes to Promote CENP-A Deposition during the Cell Cycle (2018) (36)
- A New Member of the Sin3 Family of Corepressors Is Essential for Cell Viability and Required for Retroelement Propagation in Fission Yeast (1999) (36)
- A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis (2019) (36)
- Unusual chromosome structure of fission yeast DNA in mouse cells. (1994) (35)
- Faculty Opinions recommendation of Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array. (2002) (33)
- Centromeric chromatin makes its mark. (2005) (32)
- On the connection between RNAi and heterochromatin at centromeres. (2010) (32)
- TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing (2020) (31)
- Genetic characterisation of hda1+, a putative fission yeast histone deacetylase gene (1998) (31)
- Silencing Mediated by the Schizosaccharomyces pombe HIRA Complex Is Dependent upon the Hpc2-Like Protein, Hip4 (2010) (30)
- Transposon‐driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution (2017) (30)
- Transcription-coupled changes to chromatin underpin gene silencing by transcriptional interference (2016) (30)
- Centromere localization and function of Mis18 requires Yippee‐like domain‐mediated oligomerization (2016) (28)
- Elements of chromosome structure and function in fission yeast. (1995) (28)
- Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe (2017) (28)
- Introduction of large linear minichromosomes into Schizosaccharomyces pombe by an improved transformation procedure. (1990) (28)
- Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein (2016) (28)
- Raf1 Is a DCAF for the Rik1 DDB1-Like Protein and Has Separable Roles in siRNA Generation and Chromatin Modification (2012) (27)
- Erratum (Retracted article): RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription (Nature (2005) 435 (1275-1279)) (2005) (26)
- Molecular biology. RNAi and heterochromatin--a hushed-up affair. (2002) (25)
- A DNA Polymerase α Accessory Protein, Mcl1, Is Required for Propagation of Centromere Structures in Fission Yeast (2008) (24)
- Anarchic centromeres: deciphering order from apparent chaos☆ (2014) (24)
- Telomeric Repeats Facilitate CENP-ACnp1 Incorporation via Telomere Binding Proteins (2013) (24)
- A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast (2014) (23)
- Transcriptional Silencing in the Fission Yeast: A Manifestation of Higher Order Chromosome Structure and Functions (1996) (22)
- Defects in Components of the Proteasome Enhance Transcriptional Silencing at Fission Yeast Centromeres and Impair Chromosome Segregation (1999) (22)
- Structure of bovine papillomavirus type 1 DNA in a transformed mouse cell line. (1986) (21)
- Pausing for Thought on the Boundaries of Imprinting (2000) (21)
- Loss of Dicer fowls up centromeres (2004) (21)
- Interspecies conservation of organisation and function between nonhomologous regional centromeres (2019) (20)
- Explorer Factors That Promote H 3 Chromatin Integrity during Transcription Prevent Promiscuous Deposition of CENP-A ( Cnp 1 ) in Fission Yeast (2012) (19)
- Abo1, a conserved bromodomain AAA‐ATPase, maintains global nucleosome occupancy and organisation (2015) (17)
- RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit (2017) (16)
- A systematic analysis of Trypanosoma brucei chromatin factors identifies novel protein interaction networks associated with sites of transcription initiation and termination (2021) (16)
- Fta2, an essential fission yeast kinetochore component, interacts closely with the conserved Mal2 protein. (2006) (15)
- Hap2–Ino80-facilitated transcription promotes de novo establishment of CENP-A chromatin (2019) (14)
- Retraction: RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription (2005) (13)
- Chromosome Segregation: Clamping down on Deviant Orientations (2003) (12)
- Comparison of methods for introducing vectors based on bovine papillomavirus-1 DNA into mammalian cells (1986) (12)
- DegrAAAded into Silence (2007) (11)
- SpEDIT: A fast and efficient CRISPR/Cas9 method for fission yeast (2020) (11)
- Retraction. Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing. (2005) (10)
- Analysis of small RNA in fission yeast ; centromeric siRNAs are potentially generated via a structured RNA (2009) (10)
- Fitness Landscape of the Fission Yeast Genome (2018) (10)
- Centromere and Kinetochore Structure and Function (2004) (10)
- Large domains of heterochromatin direct the formation of short mitotic chromosome loops (2020) (9)
- RNA interference, heterochromatin, and centromere function. (2004) (9)
- NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells (2021) (7)
- The RFTS Domain of Raf2 Is Required for Cul4 Interaction and Heterochromatin Integrity in Fission Yeast (2014) (6)
- Molecular Biology: Silencing Unlimited (2006) (6)
- A Schizosaccharomyces pombe artificial chromosome large DNA cloning system. (1998) (6)
- Manipulation of large minichromosomes in Schizosaccharomyces pombe with liposome-enhanced transformation. (1992) (6)
- Sim4 (2003) (5)
- Reply to “CENP-A octamers do not confer a reduction in nucleosome height by AFM” (2014) (5)
- Panspecies Small-Molecule Disruptors of Heterochromatin-Mediated Transcriptional Gene Silencing (2014) (5)
- modifications heterochromatin by promoting heterochromatin-specific histone tail Fission yeast CENP-B homologs nucleate centromeric (2002) (4)
- Establishment of centromere identity is dependent on nuclear spatial organization (2021) (4)
- Inter-species conservation of organisation and function between non-homologous regional centromeres (2018) (4)
- Telomere loss and cancer (1991) (4)
- Duplication of a viral enhancer sequence improves the stability of a vector based on BPV-1 DNA. (1986) (4)
- Correction: Telomeric Repeats Facilitate CENP-ACnp1 Incorporation via Telomere Binding Proteins (2013) (4)
- Cell division: Guardian spirit blesses meiosis (2004) (3)
- Centromeric DNA destabilizes H3 nucleosomes to promote CENP-A deposition during the cell cycle (2017) (3)
- Proteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance (2021) (2)
- Dissecting Fission Yeast Centromeres via Silencing (2001) (2)
- Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions (2018) (1)
- Epigenetic gene silencing by heterochromatin primes fungal resistance (2020) (1)
- Explorer The kinetochore proteins Pcs 1 and Mde 4 and heterochromatin are required to prevent merotelic orientation (2017) (1)
- Great chieftain o’ the fungal-race! (2000) (1)
- iNucs: inter-nucleosome interactions (2021) (1)
- The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin (2013) (1)
- Retraction (2005) (1)
- A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast (2014) (1)
- Acknowledgment of Reviewers, 2018 (2018) (0)
- 1 Swr 1 mediated H 2 A . ZPht 1 incorporation designates centromere DNA for de novo CENP-ACnp 1 assembly (2017) (0)
- Chromosome substructure investigation. Telomeres. (1994) (0)
- Explorer The RFTS domain of Raf 2 is required for Cul 4 interaction and heterochromatin integrity in fission yeast (2017) (0)
- Swr1 mediated H2A.ZPht1 incorporation designates centromere DNA for de novo CENP-ACnp1 assembly (2017) (0)
- The SPARC complex defines RNAPII promoters in Trypanosoma brucei (2022) (0)
- Crystal Structure of Mis18 'Yippee-like' Domain (2016) (0)
- Construction and analysis of vectors based on bovine papilloma virus (1985) (0)
- A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis (2019) (0)
- co cept Methylation : lost in hydroxylation ? (2013) (0)
- Cell division: Six degrees of separation (2011) (0)
- Faculty Opinions recommendation of PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin. (2002) (0)
- Interspecies conservation of organisation and function between nonhomologous regional centromeres (2019) (0)
- Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant (2013) (0)
- Explorer A nucleosome turnover map reveals that the stability of histone H 4 Lys 20 methylation depends on histone recycling in transcribed chromatin (2017) (0)
- Faculty Opinions recommendation of Molecular architecture of SMC proteins and the yeast cohesin complex. (2002) (0)
- Faculty Opinions recommendation of Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. (2002) (0)
- Chromo shadow domain from fission yeast swi6 protein. (2000) (0)
- Faculty Opinions recommendation of Characterization of HCP-6, a C. elegans protein required to prevent chromosome twisting and merotelic attachment. (2002) (0)
- Author response: Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe (2017) (0)
- Figure 3, Factors affecting outer repeat and central core silencing (2001) (0)
- deposition occurs during G 2 in fission yeastCnp 1 Quantitative single-molecule microscopy reveals that CENP-A (2012) (0)
- 2PA-165 Tumor suppression of human cell lines by the transduction of Patched virus (2000) (0)
- Chromosome Substructure Investigation (1994) (0)
- Faculty Opinions recommendation of Identification of novel histone post-translational modifications by peptide mass fingerprinting. (2003) (0)
- Supporting Online Material for Comparative Functional Genomics of the Fission Yeasts (2011) (0)
This paper list is powered by the following services:
Other Resources About Robin Allshire
What Schools Are Affiliated With Robin Allshire?
Robin Allshire is affiliated with the following schools: