Robin Lovell-Badge | Academic Influence

Robin Lovell-Badge's AcademicInfluence.com Rankings

Robin Lovell-Badge

Biology

#2485

World Rank

#3933

Historical Rank

Developmental Biology

#72

World Rank

#78

Historical Rank

Genetics

#453

World Rank

#522

Historical Rank

biology Degrees

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Biology

Why Is Robin Lovell-Badge Influential?

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According to Wikipedia, Robin Howard Lovell-Badge, CBE, FRS FMedSci is a British scientist most famous for his discovery, along with Peter Goodfellow, of the SRY gene on the Y-chromosome that is the determinant of sex in mammals. They shared the 1995 Louis-Jeantet Prize for Medicine for their discovery. He was awarded the 2022 Genetics Society Medal. He is currently a Senior Group Leader and Head of the Laboratory of Stem Cell Biology and Developmental Genetics at the Francis Crick Institute in Central London.

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Robin Lovell-Badge's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif (1990) (3069)
Multipotent cell lineages in early mouse development depend on SOX2 function. (2003) (2408)
Male development of chromosomally female mice transgenic for Sry (1991) (2085)
A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes (1990) (1644)
Circular transcripts of the testis-determining gene Sry in adult mouse testis (1993) (930)
Expression of a candidate sex-determining gene during mouse testis differentiation (1990) (857)
Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds (1996) (806)
Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation (2009) (781)
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer (2008) (601)
Expression of Sry, the mouse sex determining gene. (1995) (574)
Dax1 antagonizes Sry action in mammalian sex determination (1998) (564)
Fgf9 and Wnt4 Act as Antagonistic Signals to Regulate Mammalian Sex Determination (2006) (519)
Sox genes find their feet. (1997) (511)
A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2. (1996) (509)
Sox2 is required for sensory organ development in the mammalian inner ear (2005) (504)
A role for SOX1 in neural determination. (1998) (498)
Generation of purified neural precursors from embryonic stem cells by lineage selection (1998) (490)
Expression of the mouse anti-müllerian hormone gene suggests a role in both male and female sexual differentiation. (1991) (482)
A Model System for Study of Sex Chromosome Effects on Sexually Dimorphic Neural and Behavioral Traits (2002) (477)
DNA binding activity of recombinant SRY from normal males and XY females. (1992) (449)
Targeted Mutagenesis of the Endogenous Mouse Mis Gene Promoter In Vivo Definition of Genetic Pathways of Vertebrate Sexual Development (1999) (442)
SRY and sex determination in mammals. (1993) (419)
SRY, like HMG1, recognizes sharp angles in DNA. (1992) (417)
Mouse Dax1 expression is consistent with a role in sex determination as well as in adrenal and hypothalamus function (1996) (406)
Definition of a consensus DNA binding site for SRY. (1994) (404)
dead end, a Novel Vertebrate Germ Plasm Component, Is Required for Zebrafish Primordial Germ Cell Migration and Survival (2003) (403)
Genetic regulation of pituitary gland development in human and mouse. (2009) (386)
Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells. (2000) (384)
Rapid sequence evolution of the mammalian sex-determining gene SRY (1993) (365)
Mammalian sex determination: a molecular drama. (1999) (363)
Male-specific cell migration into the developing gonad (1997) (359)
Involvement of Sox1, 2 and 3 in the early and subsequent molecular events of lens induction. (1998) (343)
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer (2008) (338)
Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans. (2006) (334)
SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors. (2004) (333)
SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland (2008) (329)
Guidelines for the use of cell lines in biomedical research (2014) (327)
Steroidogenic factor 1 and Dax-1 colocalize in multiple cell lineages: potential links in endocrine development. (1996) (326)
Sex determination and SRY: down to a wink and a nudge? (2009) (310)
XY female mice resulting from a heritable mutation in the primary testis-determining gene, Tdy. (1990) (304)
Sox1 directly regulates the gamma-crystallin genes and is essential for lens development in mice. (1998) (302)
SOX9 induces and maintains neural stem cells (2010) (301)
Sex‐reversing mutations affect the architecture of SRY‐DNA complexes. (1994) (295)
SOX3 is required during the formation of the hypothalamo-pituitary axis (2004) (282)
Involvement of SOX proteins in lens‐specific activation of crystallin genes. (1995) (257)
SOX3 is an X-linked gene related to SRY. (1993) (255)
Over- and underdosage of SOX3 is associated with infundibular hypoplasia and hypopituitarism. (2005) (249)
Tbx6-dependent Sox2 regulation determines neural vs mesodermal fate in axial stem cells (2010) (247)
Evolution of sex determination and the Y chromosome: SRY-related sequences in marsupials (1992) (231)
Identification of SOX3 as an XX male sex reversal gene in mice and humans. (2011) (231)
Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities. (1998) (219)
Oncogenicity of the developmental transcription factor Sox9. (2012) (206)
Inverted repeat structure of the Sry locus in mice. (1992) (203)
Imbalance between neutrophil elastase and its inhibitor α1-antitrypsin in obesity alters insulin sensitivity, inflammation, and energy expenditure. (2013) (188)
The human SRY transcript. (1993) (188)
Zfy gene expression patterns are not compatible with a primary role in mouse sex determination (1989) (176)
Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination (2007) (173)
Preventing the loss of competence for neural induction: HGF/SF, L5 and Sox-2. (1997) (169)
SOX2 plays a critical role in the pituitary, forebrain, and eye during human embryonic development. (2008) (162)
The future for stem cell research (2001) (152)
Inviability of parthenogenones is determined by pronuclei, not egg cytoplasm (1984) (149)
Mobilized Adult Pituitary Stem Cells Contribute to Endocrine Regeneration in Response to Physiological Demand (2013) (149)
Sex reversal following deletion of a single distal enhancer of Sox9 (2018) (134)
Coordination of progenitor specification and growth in mouse and chick spinal cord (2014) (132)
X-chromosome inactivation may explain the difference in viability of XO humans and mice (1991) (129)
Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis (2012) (129)
The expression of murine Hox-2 genes is dependent on the differentiation pathway and displays a collinear sensitivity to retinoic acid in F9 cells and Xenopus embryos. (1991) (127)
CRISPR germline engineering—the community speaks (2015) (124)
p27Kip1 Directly Represses Sox2 during Embryonic Stem Cell Differentiation (2012) (123)
Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene. (1990) (116)
An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism. (2005) (114)
Deletion of Y chromosome sequences located outside the testis determining region can cause XY female sex reversal (1993) (111)
mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance (2016) (106)
Nervous System Regionalization Entails Axial Allocation before Neural Differentiation (2018) (105)
Sex-determining genes in mice: building pathways. (2002) (104)
Early Development of the Pituitary Gland: Induction and Shaping of Rathke’s Pouch (2005) (99)
The origin of the Mullerian duct in chick and mouse. (2007) (97)
Disruption of SoxB1-dependent Sonic hedgehog expression in the hypothalamus causes septo-optic dysplasia. (2012) (96)
PITX2 controls asymmetric gonadal development in both sexes of the chick and can rescue the degeneration of the right ovary (2007) (92)
Reciprocal Repression between Sox3 and Snail Transcription Factors Defines Embryonic Territories at Gastrulation (2011) (91)
Species- and tissue-specific expression of human alpha 1-antitrypsin in transgenic mice. (1987) (90)
The cDNA sequence and chromosomal location of the human SOX2 gene (1994) (90)
Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes (2014) (89)
Novel transcriptional targets of the SRY-HMG box transcription factor SOX4 link its expression to the development of small cell lung cancer. (2012) (89)
Sex determination and the control of Sox9 expression in mammals (2011) (88)
Neuronal Migration and Ventral Subtype Identity in the Telencephalon Depend on SOX1 (2005) (87)
ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update (2021) (82)
Genetic Control of Testis Development (2012) (79)
The HMG box of SRY is a calmodulin binding domain (1996) (79)
Assisted reproductive technologies to prevent human mitochondrial disease transmission (2017) (76)
Sry‐negative XX sex reversal in purebred dogs (1999) (76)
The Vascular Stem Cell Niche (2012) (75)
SOX3 activity during pharyngeal segmentation is required for craniofacial morphogenesis (2007) (73)
Excess DAX1 leads to XY ovotesticular disorder of sex development (DSD) in mice by inhibiting steroidogenic factor-1 (SF1) activation of the testis enhancer of SRY-box-9 (Sox9). (2012) (71)
Nestin-Cre Mice Are Affected by Hypopituitarism, Which Is Not Due to Significant Activity of the Transgene in the Pituitary Gland (2010) (69)
Expression of Sox3 throughout the developing central nervous system is dependent on the combined action of discrete, evolutionarily conserved regulatory elements (2003) (68)
iPS Cells: Mapping the Policy Issues (2009) (66)
Failure of SOX9 Regulation in 46XY Disorders of Sex Development with SRY, SOX9 and SF1 Mutations (2011) (65)
What if stem cells turn into embryos in a dish? (2015) (63)
A role for SOX 1 in neural determination (1998) (62)
Tdy-negative XY, XXY and XYY female mice: breeding data and synaptonemal complex analysis. (1993) (61)
Sry and sex determination: how lazy can it be? (2002) (60)
A MicroRNA (mmu-miR-124) Prevents Sox9 Expression in Developing Mouse Ovarian Cells1 (2013) (58)
Normal structure and expression of Zfy genes in XY female mice mutant in Tdy. (1990) (56)
The molecular genetics of Sry and its role in mammalian sex determination. (1995) (55)
Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone (2017) (55)
Dax1 expression is dependent on steroidogenic factor 1 in the developing gonad. (2002) (55)
Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue (2009) (55)
Differential extra-renal expression of the mouse renin genes. (1989) (54)
Pluripotent Stem Cell-Derived Gametes: Truth and (Potential) Consequences (2009) (54)
Widespread expression of human alpha 1-antitrypsin in transgenic mice revealed by in situ hybridization. (1989) (54)
Living with bad architecture (1995) (53)
The ZFY gene family in humans and mice. (1991) (52)
Optimization of non‐isotopic in situ hybridization on formalin‐fixed, paraffin‐embedded material using digoxigenin‐labelled probes and transgenic tissues (1992) (51)
The genes for a spliceosome protein (SAP62) and the anti-Müllerian hormone (AMH) are contiguous. (1995) (51)
Gonadal Asymmetry and Sex Determination in Birds (2014) (51)
Genome Editing Technologies and Human Germline Genetic Modification: The Hinxton Group Consensus Statement (2015) (49)
Mechanisms of gonadal morphogenesis are not conserved between chick and mouse. (2007) (49)
After the Storm - A Responsible Path for Genome Editing. (2019) (48)
Error-Prone ZW Pairing and No Evidence for Meiotic Sex Chromosome Inactivation in the Chicken Germ Line (2012) (46)
Primary sex determination in birds depends on DMRT1 dosage, but gonadal sex does not determine adult secondary sex characteristics (2021) (45)
The early history of the Sox genes. (2010) (43)
The zebrafish Zf-Sox 19 protein: a novel member of the Sox family which reveals highly conserved motifs outside of the DNA-binding domain. (1995) (43)
Pivotal role of median eminence tanycytes for hypothalamic function and neurogenesis (2017) (42)
Characterization and mapping of the human SOX4 gene (2004) (42)
The role of Sry in mammalian sex determination. (1992) (42)
Evolutionary conservation in the DNA-binding and -bending properties of HMG-boxes from SRY proteins of primates. (1995) (42)
Modulation of gene activity by consecutive gene targeting of one creatine kinase M allele in mouse embryonic stem cells. (1991) (40)
Mutations within Sox 2 / SOX 2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans (2006) (40)
Sex determining gene expression during embryogenesis. (1993) (37)
Revisiting the Warnock rule (2017) (37)
Tissue-specific expression of the human type II collagen gene in mice. (1987) (36)
Increased gene dosage of Ink4/Arf and p53 delays age-associated central nervous system functional decline (2015) (34)
Embryo Research in Pluralistic Europe (2004) (33)
Pituitary Phenotypes of Mice Lacking the Notch Signalling Ligand Delta-Like 1 Homologue (2013) (32)
Changes in protein synthesis during differentiation of embryonal carcinoma cells, and a comparison with embryo cells. (1980) (32)
The Sry Gene and Sex Determination in Mammals (1993) (31)
Human–animal cytoplasmic hybrid embryos, mitochondria, and an energetic debate (2007) (31)
Testis formation in XX individuals resulting from novel pathogenic variants in Wilms’ tumor 1 (WT1) gene (2020) (31)
A promoter trap in embryonic stem (ES) cells selects for integration of DNA into CpG islands (1991) (30)
The regulation of Sox9 expression in the gonad. (2019) (29)
Gonadal supporting cells acquire sex-specific chromatin landscapes during mammalian sex determination. (2019) (28)
Flexibility of Neural Stem Cells (2011) (28)
Setbacks on the road to sexual fulfilment (1994) (28)
Many ways to pluripotency (2007) (28)
Human COL2A1-directed SV40 T antigen expression in transgenic and chimeric mice results in abnormal skeletal development (1995) (28)
Evidence that the testis determination pathway interacts with a non-dosage compensated, X-linked gene. (2001) (26)
Transformation of embryonic stem cells with the human type-II collagen gene and its expression in chimeric mice. (1985) (26)
Oestrogen in the chick embryo can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex that can support oogenesis (2020) (26)
Identification of SOX 3 as an XX male sex reversal gene in mice and humans (2010) (25)
SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary (2016) (25)
In vivo analysis of the regulation of the anti‐Müllerian hormone, as a marker of Sertoli cell differentiation during testicular development, reveals a multi‐step process (2001) (25)
Congenital Hydrocephalus and Abnormal Subcommissural Organ Development in Sox3 Transgenic Mice (2012) (25)
CRISPR babies: a view from the centre of the storm (2019) (24)
The regulation of human embryo and stem-cell research in the United Kingdom (2008) (24)
Sox9 gene regulation and the loss of the XY/XX sex-determining mechanism in the mole vole Ellobius lutescens (2012) (23)
CRISPR: A path through the thicket (2015) (22)
A molecular approach to sex determination in mammals (1997) (22)
Transgenic animals: New advances in the field (1985) (22)
Disruption of the LF‐A1 and LF‐B1 binding sites in the human alpha‐1‐antitrypsin gene has a differential effect during development in transgenic mice. (1991) (21)
Developmental genetics. Living with bad architecture. (1995) (21)
Stem cell research policy and iPS cells (2009) (21)
Predicting the spatiotemporal dynamics of hair follicle patterns in the developing mouse (2014) (20)
Establishment and characterization of conditionally immortalized cells from the mouse urogenital ridge. (1996) (20)
Species- and tissue-specific expression o: human l-antitrypsin in transgenic mi (1987) (20)
High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response (2017) (19)
The development of XO gynogenetic mouse embryos. (1987) (19)
Integrity in International Stem Cell Research Collaborations (2006) (19)
Regulation of mesodermal precursor production by low-level expression of B1 Sox genes in the caudal lateral epiblast (2014) (17)
Two maternally derived X chromosomes contribute to parthenogenetic inviability. (1988) (17)
Sox2 : biology and role in development and disease (2016) (17)
Expression of injected HPRT minigene DNA in mouse embryos and its inhibition by antisense DNA. (1988) (17)
Human Embryo Editing: Opportunities and Importance of Transnational Cooperation. (2017) (17)
SOX3 promotes generation of committed spermatogonia in postnatal mouse testes (2020) (16)
PCR as a rapid screening method for transgenic mice. (1988) (16)
Of sex and determination: marking 25 years of Randy, the sex-reversed mouse (2016) (16)
Regenerative Medicine: Organ recital in a dish (2011) (15)
Testis determination: soft talk and kinky sex. (1992) (14)
Anti-Xistentialism (1999) (14)
NOTCH activity differentially affects alternative cell fate acquisition and maintenance (2018) (12)
Cloning and mapping of the human SOX1: a highly conserved gene expressed in the developing brain (2009) (12)
Micro‐capillary tube in situ hybridisation: A novel method for processing small individual samples (2000) (12)
Correction: Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone (2017) (10)
Characterisation of two identical independent non-homologous integration sites in mouse embryonic stem cells. (1993) (10)
Inference of Gene-Phenotype Associations via Protein-Protein Interaction and Orthology (2013) (10)
Stable transformation of mouse teratocarcinoma stem cells with the dominant selective marker Eco.gpt and retention of their developmental potentialities. (1983) (10)
Aggressive behaviour: contributions from genes on the Y chromosome. (2005) (9)
The SRY protein, like HMG 1, recognizes (CA)n sequences, an abundant repeat sequence in vertebrates. (1995) (9)
The Mouse Y Chromosome (1994) (9)
Establishing and maintaining fertility: the importance of cell cycle arrest (2021) (8)
Banking on spermatogonial stem cells: Frozen assets and foreign investments (1996) (6)
Science and law. Integrity in international stem cell research collaborations. (2006) (6)
CRISPR/Cas9 Deletion of SOX2 Regulatory Region 2 (SRR2) Decreases SOX2 Malignant Activity in Glioblastoma (2021) (6)
Title Human COL 2 A 1-directed SV 40 T antigen expression in transgenic and chimeric mice results in abnormal skeletal development (2002) (6)
Novel Tools and Investigative Approaches for the Study of Oligodendrocyte Precursor Cells (NG2-Glia) in CNS Development and Disease (2021) (6)
Testis determination: soft talk and kinky sex (1992) (6)
17 – Sex Determination and Differentiation (2002) (5)
SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice (2020) (5)
Primary sex determination in chickens depends on DMRT1 dosage, but gonadal sex does not determine secondary sexual characteristics in adult birds (2020) (5)
Applications of genome editing on laboratory animals (2021) (5)
Attitudes toward Embryo Experimentation in Europe (2003) (5)
Debate on Germline Gene Editing. (2016) (5)
Determination and differentiation. (2001) (5)
Safety of medicines and the use of animals in research (2011) (5)
Signal transducer and activator of transcription (STAT) 1 and STAT3 are expressed in the human ovary and have Janus kinase 1-independent functions in the COV434 human granulosa cell line. (2020) (5)
TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway (2022) (5)
Development of a Chromosomally Integrated Metabolite-Inducible Leu3p-α-IPM “Off-On” Gene Switch (2010) (4)
SOX9 Triggers Different Epithelial to Mesenchymal Transition States to Promote Pancreatic Cancer Progression (2022) (4)
Protein synthetic patterns of tissues in the early chick embryo. (1985) (4)
Expression of the α-fetoprotein gene in pluripotent and committed cells (1984) (4)
Erratum: Revisiting the Warnock rule (2017) (4)
Stem cell therapy and research (2002) (3)
Expression of the alpha-fetoprotein gene in pluripotent and committed cells. (1984) (3)
Perspective on Stem Cells in Developmental Biology, with Special Reference to Neuroendocrine Systems (2016) (3)
Stem-cell guidelines: why it was time for an update (2021) (3)
Developmental genetics: Too much sex is bad for males (1998) (3)
Studies of mice deleted for Sox3 and uc482: relevance to X-linked hypoparathyroidism (2020) (3)
In vitro cellular reprogramming to model gonad development and its disorders (2021) (3)
Chapter 1 – Historical Perspectives (2016) (3)
Dentate gyrus development requires a cortical hem-derived astrocytic scaffold (2020) (3)
"Male Development of Chromosomally Female Mice Transgenic for Sry gene" (1991), by (2017) (2)
In the chick embryo, estrogen can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex which supports oogenesis (2019) (2)
A freeze-dryer and a fertile imagination (1998) (2)
Approaches To the Biochemistry of Differentiation of Mouse Embryonal Carcinoma Cells (1983) (2)
Genetic and physical mapping of the murine Sox1 gene. (1996) (2)
Long-Range Regulation of Key Sex Determination Genes (2021) (2)
The Regulation of Embyro Research in Europe: Situation and Prospects (2003) (2)
Sox2 is required for sensory organ development in the inner ear (2005) (2)
SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms. (2022) (2)
Two alternative methods for the retrieval of somatic cell populations from the mouse ovary (2021) (2)
Looking for the niche: substance delivery into the lateral ventricle of the brain: the osmotic minipump system. (2013) (1)
Tumor and Stem Cell Biology Oncogenicity of the Developmental Transcription Factor Sox 9 (2012) (1)
The Properties and Functions of Glial Cell Types of the Hypothalamic Median Eminence (2022) (1)
New guidelines for stem cell and embryo research from the ISSCR. (2021) (1)
ISSCR guidelines uphold human right to science for benefit of all (2021) (1)
Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia. (2022) (1)
Role of SOX2 in the Hypothalamo–Pituitary Axis (2016) (1)
RNA FISH, DNA FISH and Chromosome Painting of Chicken Oocytes. (2016) (1)
Correction: Corrigendum: Assisted reproductive technologies to prevent human mitochondrial disease transmission (2018) (1)
Genetic and physical mapping of the murine Soxl gene (1996) (1)
07-P021 Sox3 deletion in the central nervous system affects pituitary endocrine cell size (2009) (0)
Consensus statement: Science, ethics and policy challenges of pluripotent stem cell-derived gametes - April 11, 2008 (2008) (0)
Sry and the Molecular Genetics of Mammalian Sex Determination (1994) (0)
Crosstalk between NF-kappaB and Wnt/beta-catenin pathways involved in skin appendages development (2009) (0)
Tumor and Stem Cell Biology Oncogenicity of the Developmental Transcription Factor Sox9 (2012) (0)
Functional characterization of the interaction between the stem cell factor SOX2 and the cell cycle regulator P27 in normal and cancerous stem cells (2016) (0)
Front & Back Matter (2021) (0)
09-P033 Expression of SOX3 in the urogenital ridge is associated with XX male sex reversal in mice (2009) (0)
A follistatin-BMP7 feedback circuit controls taste papillae development and patterning in mouse tongue (2009) (0)
09-P032 – Withdrawn (2009) (0)
The SOX9Y440X campomelic dysplasia mutation disrupts endolymph homeostasis (2016) (0)
Sox2 dosage defines the specification and survival of sensory neurons in the inner ear (2012) (0)
X marks the spot (1991) (0)
Regionalization of the nervous system requires axial allocation prior to neural lineage commitment (2017) (0)
Sensorineural deafness in a mouse model of campomelic dysplasia (2007) (0)
High SOX9 Maintains Glioma Stem Cell Activity through a Regulatory Loop Involving STAT3 and PML (2022) (0)
The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX (2022) (0)
Paul S. Burgoyne (1946-2020) (2020) (0)
A New Understanding, Guided by Single-Cell Sequencing, of the Establishment and Maintenance of the Ovarian Reserve in Mammals. (2022) (0)
Dysregulation of Aqp3 and endolymphatic hydrops in a mouse model of campomelic dysplasia (2013) (0)
Sox9 gene regulation and the loss of the XY/XX sex-determining mechanism in the mole vole Ellobius lutescens (2012) (0)
12-P010 Role of LIM homedomain transcription factors LHX7 and ISL1 in the specification of mouse basal forebrain cholinergic neurons (2009) (0)
Cooperation between SOX9 and SOX10 is required for hearing via regulation of genes involved in inner ear fluid homeostasis (2018) (0)
An 'Anti-Testis' Effect of DAX1-Antagonism of the Testis-Specific Enhancer of SOX9. (2010) (0)
A comparison of the properties of So Sox-1 and Sox2 (1996) (0)
Title Pluripotent Stem Cell-Derived Gametes : Truth and ( Potential ) Consequences Permalink (2009) (0)
Ethereal Ethics (2004) (0)
Predicting the establishment of hair follicle patterns in the developing mouse (2012) (0)
Investigating the sex-linked mechanisms of Hirschsprung disease using mouse models (2017) (0)
Corrigendum: Assisted reproductive technologies to prevent human mitochondrial disease transmission (2018) (0)
Title Inference of gene-phenotype associations via protein-proteininteraction and orthology (2013) (0)
Impact of Sox2 dosage on sensory neurogenesis and prosensory versus non-sensory cell fate in the inner ear (2017) (0)
177. A MECHANISM UNDERLYING DISORDERS OF SEX DEVELOPMENT CAUSED BY DAX1 DUPLICATION (2009) (0)
Hypoxia-related and Stem Cell-like Phenotypes of Young, Adult and Aged Intervertebral Disc Cells (2007) (0)
Genetics, Molecular Biology, Evolution, Endocrinology, Embryology and Pathology of Sex Determination and Diff erentiation (2008) (0)
09-P095 FOXL2 is able to repress the testis specific enhancer of SOX9 (2009) (0)
An essential role for Sox2 in inner ear development (2001) (0)
The identification of a gene expression signature of primordial follicle activation in mouse pregranulosa cells (2022) (0)
The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent gene repression of SOX2 (2022) (0)
Final general discussion (2005) (0)
Hearing and balance defects in a mouse model of campomelic dysplasia (2008) (0)
A Novel Minor Spliceosome Defect Associated with Growth Hormone Deficiency (GHD) and Primary Ovarian Insufficiency (POI) (2019) (0)
Contents Vol. 11, 2017 (2018) (0)
22-P015 Chicken oocytes and meiotic silencing (2009) (0)
Genetics of disease sampling a witch's brew, the genetics of complex systems (1999) (0)
Theoretical and Practical Possibilities in Human Embryo Experimentation (2003) (0)
Human COL2A1-directed SV40 T-antigen expression in transgenic mice results in abnormal skeletal development (1993) (0)
(embryonic stem cells/chimeras/transgenic mice/DNA-mediated gene (2016) (0)
Pathogenic Variants in RNPC3 are Associated with Hypopituitarism and Primary Ovarian Insufficiency (2021) (0)
FOXL2 interaction with different binding partners regulates the dynamics of granulosa cell differentiation across ovarian development (2023) (0)
Adult and Embryonic Stem Cells: Clinical Perspectives (2003) (0)
Sox2 regulates hair type specification and pigmentation (2013) (0)
P122. Sox2 dosage defines development and survival of sensory neurons in the inner ear (2010) (0)
Understanding the molecular pathogenesis of SOX9 Y440X campomelic dysplasia (2010) (0)
PMON275 GONAD-on-CHIP to study early gonad development and DSD (2022) (0)
Abnormal chondrocyte differentiation in COL2A1-SV40 T-antigen chimeric mice (1994) (0)
Regulation of Sox9 in the gonad during sex determination (2016) (0)
Follistatin Directs Patterning and Development of Sox2-Expressing Taste Bud Progenitors (2008) (0)
The Key Aspects of New Gene Editing Technology that Raise Broader Issues (2016) (0)
SOX3 promotes generation of committed spermatogonia in postnatal mouse testes (2020) (0)
Toward a Rational Debate on Embryo Research (2003) (0)
Rosa Beddington (1956–2001) (2001) (0)
A mouse model for hearing and balance defects in campomelic dysplasia (2007) (0)
Sox 2 Biology and Role in Development and Disease (2015) (0)
Sex, Stem Cells and Decision of Cell Fate (2014) (0)
Sox2 Is Required Independently in Both Stem and Differentiated Cells for Pituitary Tumour Genesis in P27 Null Mice (2021) (0)
Defects in cochlear structure and function in the Sox9Y440X campomelic dysplasia mouse model (2011) (0)
The Roles of Sox2 and Sox18 in Hair Follicle Specification (2006) (0)
EMBO Practical Course on Molecular Approaches to Mouse Development Max Planck Institute of Biophysical Chemistry, Göttingen, F.R.G. May 2–17,1991 (1991) (0)
A genetic approach for disease gene discovery in the mouse (2001) (0)
Anterior and posterior neural plates from epiblast are derived by distinct molecular mechanisms (2009) (0)
SOX9-positive pituitary stem cells differ according to their position in the gland and maintenance of their progeny depends on context (2023) (0)
S06-04 Molecular and developmental insights into the pathogenesis of the SOX 9 Y 440 X campomelic dysplasia mutation (2009) (0)
Summary sentence: In vitro knock-down experiments show that miR-124 is responsible for SOX9 down-regulation in developing ovarian cells Keywords: microRNA, microarray, miR-124, sex determination, gonad development, ovary, cell transfection, gene expression, regulation of translation. (2013) (0)
Uncovering essential gene function for sensory organ development in the mammalian inner ear (2003) (0)
Tbx6-dependent regulation of Sox2 enhancer N1 determines the neural vs. mesodermal fate of axial stem cells in the caudal lateral epiblast (2010) (0)

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University College London

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